Butenal (BioDeep_00000176887)
human metabolite blood metabolite
代谢物信息卡片
METHACROLEIN
化学式: C4H6O (70.0418626)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC=CC=O
InChI: InChI=1S/C4H6O/c1-2-3-4-5/h2-4H,1H3
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
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Analytica chimica acta.
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Bulletin of experimental biology and medicine.
2012 Jul; 153(3):375-7. doi:
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Carcinogenesis.
2012 Apr; 33(4):804-9. doi:
10.1093/carcin/bgs026. [PMID: 22298640] - Dan Li, Michele Ferrari, Elizabeth M Ellis. Human aldo-keto reductase AKR7A2 protects against the cytotoxicity and mutagenicity of reactive aldehydes and lowers intracellular reactive oxygen species in hamster V79-4 cells.
Chemico-biological interactions.
2012 Jan; 195(1):25-34. doi:
10.1016/j.cbi.2011.09.007. [PMID: 22001351] - Thomas W Kensler, Derek Ng, Steven G Carmella, Menglan Chen, Lisa P Jacobson, Alvaro Muñoz, Patricia A Egner, Jian Guo Chen, Geng Sun Qian, Tao Yang Chen, Jed W Fahey, Paul Talalay, John D Groopman, Jian-Min Yuan, Stephen S Hecht. Modulation of the metabolism of airborne pollutants by glucoraphanin-rich and sulforaphane-rich broccoli sprout beverages in Qidong, China.
Carcinogenesis.
2012 Jan; 33(1):101-7. doi:
10.1093/carcin/bgr229. [PMID: 22045030] - Seung Eun Lee, Hana Yang, Seong Il Jeong, Young-Ho Jin, Cheung-Seog Park, Yong Seek Park. Induction of heme oxygenase-1 inhibits cell death in crotonaldehyde-stimulated HepG2 cells via the PKC-δ-p38-Nrf2 pathway.
PloS one.
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PloS one.
2012; 7(1):e29930. doi:
10.1371/journal.pone.0029930. [PMID: 22238677] - Eşref Demir, Bülent Kaya, Carolina Soriano, Amadeu Creus, Ricard Marcos. Genotoxic analysis of four lipid-peroxidation products in the mouse lymphoma assay.
Mutation research.
2011 Dec; 726(2):98-103. doi:
10.1016/j.mrgentox.2011.07.001. [PMID: 21763450] - Hauh-Jyun Candy Chen, Wen-Peng Lin. Quantitative analysis of multiple exocyclic DNA adducts in human salivary DNA by stable isotope dilution nanoflow liquid chromatography-nanospray ionization tandem mass spectrometry.
Analytical chemistry.
2011 Nov; 83(22):8543-51. doi:
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Journal of proteomics.
2011 Oct; 74(11):2417-29. doi:
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Journal of the American Chemical Society.
2011 Jun; 133(24):9140-3. doi:
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Mutation research.
2011 Jun; 711(1-2):13-27. doi:
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Toxicology letters.
2011 Mar; 201(3):240-8. doi:
10.1016/j.toxlet.2011.01.006. [PMID: 21238556] - Olav A Christophersen, Anna Haug. Animal products, diseases and drugs: a plea for better integration between agricultural sciences, human nutrition and human pharmacology.
Lipids in health and disease.
2011 Jan; 10(?):16. doi:
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Journal of toxicology.
2011; 2011(?):645361. doi:
10.1155/2011/645361. [PMID: 21776264] - Xing-Yu Liu, Zhi-Hua Yang, Xiu-Jie Pan, Mao-Xiang Zhu, Jian-Ping Xie. Gene expression profile and cytotoxicity of human bronchial epithelial cells exposed to crotonaldehyde.
Toxicology letters.
2010 Aug; 197(2):113-22. doi:
10.1016/j.toxlet.2010.05.005. [PMID: 20471460] - Xing-yu Liu, Zhi-hua Yang, Xiu-jie Pan, Mao-xiang Zhu, Jian-ping Xie. Crotonaldehyde induces oxidative stress and caspase-dependent apoptosis in human bronchial epithelial cells.
Toxicology letters.
2010 May; 195(1):90-8. doi:
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Acta histochemica et cytochemica.
2010 May; 43(2):69-75. doi:
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Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.
2010 May; 19(5):1185-92. doi:
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Planta.
2010 Apr; 231(5):1077-88. doi:
10.1007/s00425-010-1112-2. [PMID: 20157726] - Lina Yin, Jun'ichi Mano, Shiwen Wang, Wataru Tsuji, Kiyoshi Tanaka. The involvement of lipid peroxide-derived aldehydes in aluminum toxicity of tobacco roots.
Plant physiology.
2010 Mar; 152(3):1406-17. doi:
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Antioxidants & redox signaling.
2010 Mar; 12(3):349-64. doi:
10.1089/ars.2009.2806. [PMID: 19686037] - Hauh-Jyun Candy Chen, Wen-Peng Lin. Simultaneous quantification of 1,N2-propano-2'-deoxyguanosine adducts derived from acrolein and crotonaldehyde in human placenta and leukocytes by isotope dilution nanoflow LC nanospray ionization tandem mass spectrometry.
Analytical chemistry.
2009 Dec; 81(23):9812-8. doi:
10.1021/ac9019472. [PMID: 19899782] - Akira Tani, C Nicholas Hewitt. Uptake of aldehydes and ketones at typical indoor concentrations by houseplants.
Environmental science & technology.
2009 Nov; 43(21):8338-43. doi:
10.1021/es9020316. [PMID: 19924966] - Ana Paula M Loureiro, Wenbing Zhang, Fekadu Kassie, Siyi Zhang, Peter W Villalta, Mingyao Wang, Stephen S Hecht. Mass spectrometric analysis of a cyclic 7,8-butanoguanine adduct of N-nitrosopyrrolidine: comparison to other N-nitrosopyrrolidine adducts in rat hepatic DNA.
Chemical research in toxicology.
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10.1021/tx900238t. [PMID: 19761253] - Beata Janowska, Marek Komisarski, Paulina Prorok, Beata Sokołowska, Jarosław Kuśmierek, Celina Janion, Barbara Tudek. Nucleotide excision repair and recombination are engaged in repair of trans-4-hydroxy-2-nonenal adducts to DNA bases in Escherichia coli.
International journal of biological sciences.
2009 Sep; 5(6):611-20. doi:
10.7150/ijbs.5.611. [PMID: 19834545] - Linlin Zhong, Ziwen Liu, Ruilan Yan, Stephen Johnson, Yupei Zhao, Xiubin Fang, Deliang Cao. Aldo-keto reductase family 1 B10 protein detoxifies dietary and lipid-derived alpha, beta-unsaturated carbonyls at physiological levels.
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2009 Sep; 387(2):245-50. doi:
10.1016/j.bbrc.2009.06.123. [PMID: 19563777] - Jun'ichi Mano, Fumitaka Miyatake, Eiji Hiraoka, Masahiro Tamoi. Evaluation of the toxicity of stress-related aldehydes to photosynthesis in chloroplasts.
Planta.
2009 Sep; 230(4):639-48. doi:
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2009 May; 22(5):759-78. doi:
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Journal of the American Chemical Society.
2009 Apr; 131(16):5994-6002. doi:
10.1021/ja900545m. [PMID: 19382815] - Steven G Carmella, Menglan Chen, Shaomei Han, Anna Briggs, Joni Jensen, Dorothy K Hatsukami, Stephen S Hecht. Effects of smoking cessation on eight urinary tobacco carcinogen and toxicant biomarkers.
Chemical research in toxicology.
2009 Apr; 22(4):734-41. doi:
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Biochemistry.
2009 Feb; 48(4):800-9. doi:
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2008 Sep; 21(9):1733-8. doi:
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2008 Jul; 41(7):793-804. doi:
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Free radical research.
2008 Apr; 42(4):344-53. doi:
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Cancer research.
2007 Dec; 67(23):11117-22. doi:
10.1158/0008-5472.can-07-3028. [PMID: 18056434] - Urmila Nair, Helmut Bartsch, Jagadeesan Nair. Lipid peroxidation-induced DNA damage in cancer-prone inflammatory diseases: a review of published adduct types and levels in humans.
Free radical biology & medicine.
2007 Oct; 43(8):1109-20. doi:
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Microbiology (Reading, England).
2007 Aug; 153(Pt 8):2613-2620. doi:
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Neuropathology : official journal of the Japanese Society of Neuropathology.
2007 Feb; 27(1):49-61. doi:
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Human & experimental toxicology.
2007 Jan; 26(1):37-47. doi:
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Inhalation toxicology.
2006 Sep; 18(10):821-9. doi:
10.1080/08958370600747945. [PMID: 16774872] - G Luna, M T Morales, R Aparicio. Changes induced by UV radiation during virgin olive oil storage.
Journal of agricultural and food chemistry.
2006 Jun; 54(13):4790-4. doi:
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Acta neuropathologica.
2006 May; 111(5):422-9. doi:
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Medical hypotheses.
2006; 67(1):151-6. doi:
10.1016/j.mehy.2005.10.034. [PMID: 16564645] - Tetsuji Hirao, Motoji Takahashi. Carbonylation of cornified envelopes in the stratum corneum.
FEBS letters.
2005 Dec; 579(30):6870-4. doi:
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Biochemical pharmacology.
2005 Jun; 69(12):1879-90. doi:
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Przeglad lekarski.
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Acta biochimica Polonica.
2005; 52(1):149-65. doi:
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Organic & biomolecular chemistry.
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Journal of immunology (Baltimore, Md. : 1950).
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Plant & cell physiology.
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Chemico-biological interactions.
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Biochimica et biophysica acta.
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Cellular & molecular biology letters.
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Cancer letters.
2002 Nov; 185(1):13-9. doi:
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Chemical research in toxicology.
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Mutation research.
2002 Apr; 516(1-2):81-9. doi:
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Chemical research in toxicology.
2002 Mar; 15(3):367-72. doi:
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Mutation research.
2001 Nov; 483(1-2):65-72. doi:
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The Journal of biological chemistry.
2001 Jun; 276(26):23903-13. doi:
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Biochimica et biophysica acta.
2001 Apr; 1531(3):188-208. doi:
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