Garlon (BioDeep_00000001593)

   

human metabolite blood metabolite


代谢物信息卡片


Triclopyr-(3,5,6-trichloro-2-pyridl-oxyacetic acid)

化学式: C7H4Cl3NO3 (254.92567640000001)
中文名称: 绿草定
谱图信息: 最多检出来源 Viridiplantae(plant) 97.37%

分子结构信息

SMILES: C1=C(C(=NC(=C1Cl)Cl)OCC(=O)O)Cl
InChI: InChI=1S/C7H4Cl3NO3/c8-3-1-4(9)7(11-6(3)10)14-2-5(12)13/h1H,2H2,(H,12,13)

描述信息

CONFIDENCE standard compound; INTERNAL_ID 59; DATASET 20200303_ENTACT_RP_MIX502; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4237; ORIGINAL_PRECURSOR_SCAN_NO 4232
CONFIDENCE standard compound; INTERNAL_ID 59; DATASET 20200303_ENTACT_RP_MIX502; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4245; ORIGINAL_PRECURSOR_SCAN_NO 4242
CONFIDENCE standard compound; INTERNAL_ID 59; DATASET 20200303_ENTACT_RP_MIX502; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4244; ORIGINAL_PRECURSOR_SCAN_NO 4241
CONFIDENCE standard compound; EAWAG_UCHEM_ID 2946
EAWAG_UCHEM_ID 2946; CONFIDENCE standard compound
D010575 - Pesticides > D006540 - Herbicides
D016573 - Agrochemicals

同义名列表

10 个代谢物同义名

Triclopyr-(3,5,6-trichloro-2-pyridl-oxyacetic acid); 2-[(3,5,6-trichloropyridin-2-yl)oxy]acetic acid; 3,5,6-trichloro-2-Pyridyloxyacetic acid; Triclopyr triethylamine salt; Triclopyr butoxyethyl ester; Release brand OF triclopyr; Triclopyr-triethylammonium; Trichlopyr; TRICLOPYR; Garlon



数据库引用编号

30 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Fitri Widhiastuti, William Rajendram, Biplob Kumar Pramanik. Understanding the risk of using herbicides for tree root removal into wastewater treatment plant performance. Chemosphere. 2023 Jun; 337(?):139345. doi: 10.1016/j.chemosphere.2023.139345. [PMID: 37379978]
  • Chelsea L Voinorosky, Katherine M Standen, Katherine J Stewart. Environmental Impact of Triclopyr on Habitat Quality in Boreal Rights-of-Way. Environmental toxicology and chemistry. 2022 12; 41(12):2955-2967. doi: 10.1002/etc.5475. [PMID: 36039969]
  • Susan M Barlow, Claire Terry, Sean Gehen, Marco Corvaro. Reproductive and developmental evaluations of triclopyr acid, triclopyr butoxyethyl ester and triclopyr triethylamine salt in the rat. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2022 Mar; 161(?):112806. doi: 10.1016/j.fct.2021.112806. [PMID: 34995710]
  • Amanda N Curtis, Maria Gabriela Bidart. Increased Temperature Influenced Growth and Development of Lithobates pipiens Tadpoles Exposed to Leachates of the Invasive Plant European Buckthorn (Rhamnus cathartica) and a Triclopyr Herbicide. Environmental toxicology and chemistry. 2021 09; 40(9):2547-2558. doi: 10.1002/etc.5142. [PMID: 34143893]
  • Enrica Bianchi, Eduardo Costa, Zhongyu June Yan, Lynea Murphy, Jessica Howell, Donna Anderson, Push Mukerji, Anand Venkatraman, Claire Terry, Kamin J Johnson. A rat subchronic study transcriptional point of departure estimates a carcinogenicity study apical point of departure. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2021 Jan; 147(?):111869. doi: 10.1016/j.fct.2020.111869. [PMID: 33217531]
  • K Z Isoardi, C B Page, M S Roberts, G K Isbister. Life-threatening triclopyr poisoning due to diethylene glycol monoethyl ether solvent. Clinical toxicology (Philadelphia, Pa.). 2021 Jan; 59(1):61-64. doi: 10.1080/15563650.2020.1757103. [PMID: 32336161]
  • Michael Bartels, Colin Brown, Git Chung, Melissa Chan, Claire Terry, Sean Gehen, Marco Corvaro. Review of the pharmacokinetics and metabolism of triclopyr herbicide in mammals: Impact on safety assessments. Regulatory toxicology and pharmacology : RTP. 2020 Oct; 116(?):104714. doi: 10.1016/j.yrtph.2020.104714. [PMID: 32640299]
  • Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. Molecular pharmacology. 2019 11; 96(5):629-640. doi: 10.1124/mol.119.115964. [PMID: 31515284]
  • Amanda N Curtis, M Gabriela Bidart. Effects of chemical management for invasive plants on the performance of Lithobates pipiens tadpoles. Environmental toxicology and chemistry. 2017 11; 36(11):2958-2964. doi: 10.1002/etc.3859. [PMID: 28498523]
  • Amy E Yahnke, Christian E Grue, Marc P Hayes, Schuyler Pearman-Gillman. Effects of the herbicide triclopyr on metamorphic northern red-legged frogs. Environmental toxicology and chemistry. 2017 09; 36(9):2316-2326. doi: 10.1002/etc.3767. [PMID: 28186362]
  • Krystal M Isbister, Eric G Lamb, Katherine J Stewart. Herbicide Toxicity Testing with Non-Target Boreal Plants: The Sensitivity of Achillea millefolium L. and Chamerion angustifolium L. to Triclopyr and Imazapyr. Environmental management. 2017 07; 60(1):136-156. doi: 10.1007/s00267-017-0867-7. [PMID: 28424880]
  • Pablo Souza-Alonso, Alejandra Guisande, Luís González. Structural changes in soil communities after triclopyr application in soils invaded by Acacia dealbata Link. Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes. 2015; 50(3):184-9. doi: 10.1080/03601234.2015.982419. [PMID: 25602151]
  • David F Spencer. Evaluation of stem injection for managing giant reed (Arundo donax). Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes. 2014; 49(9):633-8. doi: 10.1080/03601234.2014.922397. [PMID: 25035911]
  • John D Stark, Xue Dong Chen, Catherine S Johnson. Effects of herbicides on Behr's metalmark butterfly, a surrogate species for the endangered butterfly, Lange's metalmark. Environmental pollution (Barking, Essex : 1987). 2012 May; 164(?):24-7. doi: 10.1016/j.envpol.2012.01.011. [PMID: 22310058]
  • Christine Böttcher, Paul K Boss, Christopher Davies. Acyl substrate preferences of an IAA-amido synthetase account for variations in grape (Vitis vinifera L.) berry ripening caused by different auxinic compounds indicating the importance of auxin conjugation in plant development. Journal of experimental botany. 2011 Aug; 62(12):4267-80. doi: 10.1093/jxb/err134. [PMID: 21543520]
  • Jerry M Green, Micheal D K Owen. Herbicide-resistant crops: utilities and limitations for herbicide-resistant weed management. Journal of agricultural and food chemistry. 2011 Jun; 59(11):5819-29. doi: 10.1021/jf101286h. [PMID: 20586458]
  • Xiaofei Zhang, Sandra Acevedo, Yingfu Chao, Zhenshan Chen, Travis Dinoff, Jeffrey Driver, John Ross, Ryan Williams, Robert Krieger. Concurrent 2,4-D and triclopyr biomonitoring of backpack applicators, mixer/loader and field supervisor in forestry. Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes. 2011; 46(4):281-93. doi: 10.1080/03601234.2011.559424. [PMID: 21500074]
  • Boris Eyheraguibel, Claire Richard, Gérard Ledoigt, Alexandra Ter Halle. Photoprotection by plant extracts: a new ecological means to reduce pesticide photodegradation. Journal of agricultural and food chemistry. 2010 Sep; 58(17):9692-6. doi: 10.1021/jf101792h. [PMID: 20707341]
  • William A Battaglin, Karen C Rice, Michael J Focazio, Sue Salmons, Robert X Barry. The occurrence of glyphosate, atrazine, and other pesticides in vernal pools and adjacent streams in Washington, DC, Maryland, Iowa, and Wyoming, 2005-2006. Environmental monitoring and assessment. 2009 Aug; 155(1-4):281-307. doi: 10.1007/s10661-008-0435-y. [PMID: 18677547]
  • Robin M Whyatt, Robin Garfinkel, Lori A Hoepner, Howard Andrews, Darrell Holmes, Megan K Williams, Andria Reyes, Diurka Diaz, Frederica P Perera, David E Camann, Dana B Barr. A biomarker validation study of prenatal chlorpyrifos exposure within an inner-city cohort during pregnancy. Environmental health perspectives. 2009 Apr; 117(4):559-67. doi: 10.1289/ehp.0800041. [PMID: 19440494]
  • Boris Eyheraguibel, Alexandra Ter Halle, Claire Richard. Photodegradation of bentazon, clopyralid, and triclopyr on model leaves: importance of a systematic evaluation of pesticide photostability on crops. Journal of agricultural and food chemistry. 2009 Mar; 57(5):1960-6. doi: 10.1021/jf803282f. [PMID: 19222158]
  • Jenny R Lenkowski, J Michael Reed, Lisa Deininger, Kelly A McLaughlin. Perturbation of organogenesis by the herbicide atrazine in the amphibian Xenopus laevis. Environmental health perspectives. 2008 Feb; 116(2):223-30. doi: 10.1289/ehp.10742. [PMID: 18288322]
  • E W Carney, R Billington, S M Barlow. Developmental toxicity evaluation of triclopyr butoxyethyl ester and triclopyr triethylamine salt in the CD rat. Reproductive toxicology (Elmsford, N.Y.). 2007 Feb; 23(2):165-74. doi: 10.1016/j.reprotox.2006.11.009. [PMID: 17194567]
  • Lingtian Xie, Kelly Thrippleton, Mary Ann Irwin, Geoffrey S Siemering, Abdou Mekebri, David Crane, Kevin Berry, Daniel Schlenk. Evaluation of estrogenic activities of aquatic herbicides and surfactants using an rainbow trout vitellogenin assay. Toxicological sciences : an official journal of the Society of Toxicology. 2005 Oct; 87(2):391-8. doi: 10.1093/toxsci/kfi249. [PMID: 16049272]
  • Nathalie H Gosselin, Robert C Brunet, Gaétan Carrier, Amssétou Dosso. Worker exposures to triclopyr: risk assessment through measurements in urine samples. The Annals of occupational hygiene. 2005 Jul; 49(5):415-22. doi: 10.1093/annhyg/meh106. [PMID: 15703284]
  • Brian V Ottis, John D Mattice, Ronald E Talbert. Determination of antagonism between cyhalofop-butyl and other rice (Oryza sativa) herbicides in barnyardgrass (Echinochloa crus-galli). Journal of agricultural and food chemistry. 2005 May; 53(10):4064-8. doi: 10.1021/jf050006d. [PMID: 15884840]
  • Tapas K Sar, Biplab Bagchi, Shyamal K Das, Tapan K Mandal, Animesh K Chakraborty, Anjan Bhattacharyya, Ashim Choudhury. Toxicokinetics, recovery, and metabolism of triclopyr butotyl (ACTP) ester in goats. Journal of agricultural and food chemistry. 2002 Jul; 50(15):4202-9. doi: 10.1021/jf011350n. [PMID: 12105946]
  • Eiki Watanabe, Ryoko Hoshino, Yukiko Kanzaki, Hiroshi Tokumoto, Hiroaki Kubo, Hiroyuki Nakazawa. New approach to immunochemical determinations for triclopyr and 3,5,6-trichloro-2-pyridinol by using a bifunctional hapten, and evaluation of polyclonal antiserum. Journal of agricultural and food chemistry. 2002 Jun; 50(13):3637-46. doi: 10.1021/jf0114684. [PMID: 12059137]
  • Allan J Cessna, Raj Grover, Don T Waite. Environmental fate of triclopyr. Reviews of environmental contamination and toxicology. 2002; 174(?):19-48. doi: 10.1007/978-1-4757-4260-2_2. [PMID: 12132342]
  • C Timchalk, R J Nolan. Pharmacokinetics of triclopyr (3,5,6-trichloro-2-pyridinyloxyacetic acid) in the beagle dog and rhesus monkey: perspective on the reduced capacity of dogs to excrete this organic acid relative to the rat, monkey, and human. Toxicology and applied pharmacology. 1997 Jun; 144(2):268-78. doi: 10.1006/taap.1997.8136. [PMID: 9194410]
  • C Timchalk, D R Finco, J F Quast. Evaluation of renal function in rhesus monkeys and comparison to beagle dogs following oral administration of the organic acid triclopyr (3,5,6-trichloro-2-pyridinyloxyacetic acid). Fundamental and applied toxicology : official journal of the Society of Toxicology. 1997 Mar; 36(1):47-53. doi: 10.1006/faat.1996.2285. [PMID: 9073466]
  • C Timchalk, M D Dryzga, P E Kastl. Pharmacokinetics and metabolism of triclopyr 3,5,6-trichloro-2-pyridinyloxyacetic acid) in Fischer 344 rats. Toxicology. 1990 May; 62(1):71-87. doi: 10.1016/0300-483x(90)90032-c. [PMID: 2343458]
  • N G Carmichael, R J Nolan, J M Perkins, R Davies, S J Warrington. Oral and dermal pharmacokinetics of triclopyr in human volunteers. Human toxicology. 1989 Nov; 8(6):431-7. doi: 10.1177/096032718900800602. [PMID: 2591984]