CHALCOMYCIN (BioDeep_00000010830)

   


代谢物信息卡片


(1R,2R,3R,6E,8S,9S,10S,12S,14E,16R)-12-hydroxy-2-[[(2R,3R,4R,5R,6R)-5-hydroxy-3,4-dimethoxy-6-methyloxan-2-yl]oxymethyl]-9-[(2S,3R,4S,6R)-3-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-3,8,10,12-tetramethyl-4,17-dioxabicyclo[14.1.0]heptadeca-6,14-diene-5,13-dione

化学式: C35H56O14 (700.367)
中文名称:
谱图信息: 最多检出来源 not specific(not specific) 0%

分子结构信息

SMILES: CC1CC(C(C(O1)OC2C(CC(C(=O)C=CC3C(O3)C(C(OC(=O)C=CC2C)C)COC4C(C(C(C(O4)C)O)OC)OC)(C)O)C)O)OC
InChI: InChI=1S/C35H56O14/c1-17-10-13-26(37)46-20(4)22(16-44-34-32(43-9)31(42-8)27(38)21(5)47-34)30-23(48-30)11-12-25(36)35(6,40)15-18(2)29(17)49-33-28(39)24(41-7)14-19(3)45-33/h10-13,17-24,27-34,38-40H,14-16H2,1-9H3/b12-11+,13-10+/t17-,18-,19+,20+,21+,22+,23+,24-,27+,28+,29+,30+,31+,32+,33-,34+,35-/m0/s1



数据库引用编号

10 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 2 CALR, RPL17
Peripheral membrane protein 1 HSD17B6
Endoplasmic reticulum membrane 1 CALR
Nucleus 2 CALR, RPL17
cytosol 2 CALR, RPL17
Early endosome membrane 1 HSD17B6
Multi-pass membrane protein 1 CACNA1I
cell surface 1 CALR
glutamatergic synapse 1 CALR
postsynapse 1 CALR
smooth endoplasmic reticulum 1 CALR
Cytoplasm, cytosol 1 CALR
acrosomal vesicle 1 CALR
plasma membrane 1 CACNA1I
Membrane 2 CACNA1I, CALR
extracellular exosome 1 CALR
Lumenal side 1 HSD17B6
endoplasmic reticulum 2 CALR, HSD17B6
extracellular space 1 CALR
perinuclear region of cytoplasm 1 CALR
intracellular membrane-bounded organelle 1 HSD17B6
Microsome membrane 1 HSD17B6
extracellular region 1 CALR
external side of plasma membrane 1 CALR
Secreted, extracellular space, extracellular matrix 1 CALR
focal adhesion 1 CALR
collagen-containing extracellular matrix 1 CALR
phagocytic vesicle membrane 1 CALR
nuclear envelope 1 CALR
endoplasmic reticulum quality control compartment 1 CALR
endoplasmic reticulum lumen 1 CALR
voltage-gated calcium channel complex 1 CACNA1I
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 CALR
Sarcoplasmic reticulum lumen 1 CALR
lumenal side of endoplasmic reticulum membrane 1 CALR
MHC class I peptide loading complex 1 CALR
cytosolic ribosome 1 RPL17
endocytic vesicle lumen 1 CALR
ribosome 1 CALR
cytosolic large ribosomal subunit 1 RPL17
Cytoplasmic vesicle, secretory vesicle, Cortical granule 1 CALR
cortical granule 1 CALR
Cytolytic granule 1 CALR
large ribosomal subunit 1 RPL17


文献列表

  • Ping Dai, Chuan-Xi Wang, Hao Gao, Qiao-Zhen Wang, Xiao-Long Tang, Guo-Dong Chen, Kui Hong, Dan Hu, Xin-Sheng Yao. Characterization of Methyltransferase AlmCII in Chalcomycin Biosynthesis: The First TylF Family O-Methyltransferase Works on a 4'-Deoxysugar. Chembiochem : a European journal of chemical biology. 2017 08; 18(15):1510-1517. doi: 10.1002/cbic.201700216. [PMID: 28488816]
  • Shutai Jiang, Lili Zhang, Xuechang Pei, Fang Deng, Dan Hu, Guodong Chen, Chuanxi Wang, Kui Hong, Xinsheng Yao, And Hao Gao. Chalcomycins from Marine-Derived Streptomyces sp. and Their Antimicrobial Activities. Marine drugs. 2017 May; 15(6):. doi: 10.3390/md15060153. [PMID: 28555051]
  • Chuan-Xi Wang, Rong Ding, Shu-Tai Jiang, Jin-Shan Tang, Dan Hu, Guo-Dong Chen, Feng Lin, Kui Hong, Xin-Sheng Yao, Hao Gao. Aldgamycins J-O, 16-Membered Macrolides with a Branched Octose Unit from Streptomycetes sp. and Their Antibacterial Activities. Journal of natural products. 2016 10; 79(10):2446-2454. doi: 10.1021/acs.jnatprod.6b00200. [PMID: 27690254]