Biological Pathway: BioCyc:META_PWY0-1336

NADH to fumarate electron transfer related metabolites

find 15 related metabolites which is associated with the biological pathway NADH to fumarate electron transfer

this pathway object is a conserved pathway across multiple organism.

View the spectrum consensus network of the metabolites related with current biological pathway.

2-heptyl-4-hydroxyquinoline N-oxide

2-Heptyl-4-hydroxyquinoline N-oxide

C16H21NO2 (259.1572)


HQNO, secreted by P. aeruginosa, is a potent electron transport chain inhibitor with a Kd of 64 nM for complex III[1]. HQNO is a potent inhibitor of mitochondrial NDH-2 in many species[2]. HQNO, secreted by P. aeruginosa, is a potent electron transport chain inhibitor with a Kd of 64 nM for complex III[1]. HQNO is a potent inhibitor of mitochondrial NDH-2 in many species[2].

   

Hydrogen Ion

Hydrogen cation

H+ (1.0078)


Hydrogen ion, also known as proton or h+, is a member of the class of compounds known as other non-metal hydrides. Other non-metal hydrides are inorganic compounds in which the heaviest atom bonded to a hydrogen atom is belongs to the class of other non-metals. Hydrogen ion can be found in a number of food items such as lowbush blueberry, groundcherry, parsley, and tarragon, which makes hydrogen ion a potential biomarker for the consumption of these food products. Hydrogen ion exists in all living organisms, ranging from bacteria to humans. In humans, hydrogen ion is involved in several metabolic pathways, some of which include cardiolipin biosynthesis cl(i-13:0/a-25:0/a-21:0/i-15:0), cardiolipin biosynthesis cl(a-13:0/a-17:0/i-13:0/a-25:0), cardiolipin biosynthesis cl(i-12:0/i-13:0/a-17:0/a-15:0), and cardiolipin biosynthesis CL(16:1(9Z)/22:5(4Z,7Z,10Z,13Z,16Z)/18:1(11Z)/22:5(7Z,10Z,13Z,16Z,19Z)). Hydrogen ion is also involved in several metabolic disorders, some of which include de novo triacylglycerol biosynthesis TG(20:3(8Z,11Z,14Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)/22:5(7Z,10Z,13Z,16Z,19Z)), de novo triacylglycerol biosynthesis TG(18:2(9Z,12Z)/20:0/20:4(5Z,8Z,11Z,14Z)), de novo triacylglycerol biosynthesis TG(18:4(6Z,9Z,12Z,15Z)/18:3(9Z,12Z,15Z)/18:4(6Z,9Z,12Z,15Z)), and de novo triacylglycerol biosynthesis TG(24:0/20:5(5Z,8Z,11Z,14Z,17Z)/24:0). A hydrogen ion is created when a hydrogen atom loses or gains an electron. A positively charged hydrogen ion (or proton) can readily combine with other particles and therefore is only seen isolated when it is in a gaseous state or a nearly particle-free space. Due to its extremely high charge density of approximately 2×1010 times that of a sodium ion, the bare hydrogen ion cannot exist freely in solution as it readily hydrates, i.e., bonds quickly. The hydrogen ion is recommended by IUPAC as a general term for all ions of hydrogen and its isotopes. Depending on the charge of the ion, two different classes can be distinguished: positively charged ions and negatively charged ions . Hydrogen ion is recommended by IUPAC as a general term for all ions of hydrogen and its isotopes. Depending on the charge of the ion, two different classes can be distinguished: positively charged ions and negatively charged ions. Under aqueous conditions found in biochemistry, hydrogen ions exist as the hydrated form hydronium, H3O+, but these are often still referred to as hydrogen ions or even protons by biochemists. [Wikipedia])

   

Pyo II

2-n-Heptyl-4-hydroxyquinoline N-oxide

C16H21NO2 (259.1572)


HQNO, secreted by P. aeruginosa, is a potent electron transport chain inhibitor with a Kd of 64 nM for complex III[1]. HQNO is a potent inhibitor of mitochondrial NDH-2 in many species[2]. HQNO, secreted by P. aeruginosa, is a potent electron transport chain inhibitor with a Kd of 64 nM for complex III[1]. HQNO is a potent inhibitor of mitochondrial NDH-2 in many species[2].

   

Nicotinamide adenine dinucleotide

[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl] [(2R,3S,4R,5R)-5-(3-carbamoylpyridin-1-ium-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphate

C21H26N7O14P2- (662.1013)


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fumarate

fumarate

C4H2O4-2 (113.9953)


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Oxalacetate

Oxalacetate

C4H2O5-2 (129.9902)


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Pentachlorophenolate

Pentachlorophenolate

C6Cl5O- (262.8392)


A phenolate anion that is the conjugate base of pentachlorophenol; major species at pH 7.3.

   

IronSULFUR CLUSTER

IronSULFUR CLUSTER

Fe4H4S4-4 (355.6593)


   

Malonate

Malonate

C3H2O4-2 (101.9953)


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Succinate

Succinate

C4H4O4-2 (116.011)


   

beta-NADH

beta-NADH

C21H27N7O14P2-2 (663.1091)


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FAD trianion

FAD trianion

C27H30N9O15P2-3 (782.1337)


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Iron;iron(2+);sulfanide

Iron;iron(2+);sulfanide

Fe3H4S4-2 (299.7244)


   

FE2/S2 (Inorganic) cluster

FE2/S2 (Inorganic) cluster

Fe2H2S2 (177.8297)


   

Hydrogen cation

Hydrogen cation

H+ (1.0078)