NCBI Taxonomy: 44249
Paenibacillus (ncbi_taxid: 44249)
found 129 associated metabolites at genus taxonomy rank level.
Ancestor: Paenibacillaceae
Child Taxonomies: Paenibacillus alvei, Paenibacillus durus, Paenibacillus lautus, Paenibacillus larvae, Paenibacillus pabuli, Paenibacillus validus, Paenibacillus peoriae, Paenibacillus polymyxa, Paenibacillus apiarius, Paenibacillus kobensis, Paenibacillus macerans, Paenibacillus apii, Paenibacillus pini, Paenibacillus alba, Paenibacillus caui, Paenibacillus humi, Paenibacillus soli, Paenibacillus apis, Paenibacillus vini, Paenibacillus piri, Paenibacillus zeae, Paenibacillus agri, Paenibacillus edaphicus, Paenibacillus chibensis, Paenibacillus ihuae, Paenibacillus ripae, Paenibacillus antri, Paenibacillus elymi, Paenibacillus rigui, Paenibacillus lacus, Paenibacillus albus, Paenibacillus horti, Paenibacillus aceti, Paenibacillus dauci, Paenibacillus pueri, Paenibacillus bovis, Paenibacillus soyae, Paenibacillus sputi, Paenibacillus elgii, Paenibacillus lentus, Paenibacillus puerhi, Paenibacillus hordei, Paenibacillus sabuli, Paenibacillus oceani, Paenibacillus populi, Paenibacillus silvae, Paenibacillus tyrfis, Paenibacillus vortex, Paenibacillus agilis, Paenibacillus ihumii, Paenibacillus luteus, Paenibacillus solani, Paenibacillus lutrae, Paenibacillus abyssi, Paenibacillus wynnii, Paenibacillus lemnae, Paenibacillus velaei, Paenibacillus cookii, Paenibacillus glebae, Paenibacillus faecis, Paenibacillus brevis, Paenibacillus aceris, Paenibacillus tumbae, Paenibacillus nuruki, Paenibacillus lupini, Paenibacillus lactis, Paenibacillus etheri, Paenibacillus typhae, Paenibacillus oralis, Paenibacillus oryzae, Paenibacillus roseus, Paenibacillus terrae, Paenibacillus zeisoli, Paenibacillus mobilis, Paenibacillus tritici, Paenibacillus filicis, Paenibacillus segetis, Paenibacillus marinum, Paenibacillus sabinae, Paenibacillus terreus, Paenibacillus tundrae, Paenibacillus paridis, Paenibacillus tuaregi, Paenibacillus harenae, Paenibacillus selenii, Paenibacillus arenosi, Paenibacillus silagei, Paenibacillus insulae, Paenibacillus cremeus, Paenibacillus humicus, Paenibacillus albidus, Paenibacillus quercus, Paenibacillus ottowii, Paenibacillus jamilae, Paenibacillus cineris, environmental samples, Paenibacillus residui, Paenibacillus ihbetae, Paenibacillus amylolyticus, Paenibacillus phytorum, Paenibacillus germinis, Paenibacillus enshidis, Paenibacillus mangrovi, Paenibacillus gorillae, Paenibacillus catalpae, Paenibacillus pinihumi, Paenibacillus borealis, Paenibacillus nanensis, Paenibacillus cavernae, Paenibacillus algicola, Paenibacillus faecalis, Paenibacillus spiritus, Paenibacillus urinalis, Paenibacillus vulneris, Paenibacillus limicola, Paenibacillus glycinis, Paenibacillus mendelii, Paenibacillus sophorae, Paenibacillus agricola, Paenibacillus herberti, Paenibacillus cymbidii, Paenibacillus polygoni, Paenibacillus puernese, Paenibacillus tylopili, Paenibacillus swuensis, Paenibacillus telluris, Paenibacillus mellifer, Paenibacillus jilunlii, Paenibacillus pinisoli, Paenibacillus uliginis, Paenibacillus paeoniae, Paenibacillus arcticus, Paenibacillus spongiae, Paenibacillus sinensis, Paenibacillus sepulcri, Paenibacillus graminis, Paenibacillus odorifer, Paenibacillus foliorum, Paenibacillus mucilaginosus, Paenibacillus alginolyticus, Paenibacillus chondroitinus, Paenibacillus illinoisensis, Paenibacillus dendrobii, Paenibacillus vandeheii, Paenibacillus siamensis, Paenibacillus stellifer, Paenibacillus cathormii, Paenibacillus helianthi, Paenibacillus sediminis, Paenibacillus castaneae, Paenibacillus monticola, Paenibacillus profundus, Paenibacillus sedimenti, Paenibacillus aestuarii, Paenibacillus arachidis, Paenibacillus sanguinis, Paenibacillus thalictri, Paenibacillus phoenicis, Paenibacillus piscarius, Paenibacillus oryzisoli, Paenibacillus camelliae, Paenibacillus ehimensis, Paenibacillus caespitis, Paenibacillus fujiensis, Paenibacillus intestini, Paenibacillus brassicae, Paenibacillus terrigena, Paenibacillus koreensis, Paenibacillus glacialis, Paenibacillus ferrarius, Paenibacillus popilliae, Paenibacillus eucommiae, Paenibacillus wenxiniae, Paenibacillus terricola, Paenibacillus chinensis, Paenibacillus aurantius, Paenibacillus fonticola, Paenibacillus plantarum, Paenibacillus glucanolyticus, Paenibacillus taihuensis, Paenibacillus tarimensis, Paenibacillus nicotianae, Paenibacillus shunpengii, Paenibacillus albicereus, Paenibacillus whitsoniae, Paenibacillus forsythiae, Paenibacillus mesophilus, Paenibacillus tibetensis, Paenibacillus albiflavus, Paenibacillus favisporus, Paenibacillus aquistagni, Paenibacillus gansuensis, Paenibacillus rhizoryzae, Paenibacillus maysiensis, Paenibacillus hispanicus, Paenibacillus ruminocola, Paenibacillus timonensis, Paenibacillus hunanensis, Paenibacillus panacihumi, Paenibacillus silvestris, Paenibacillus protaetiae, Paenibacillus purispatii, Paenibacillus kribbensis, Paenibacillus assamensis, Paenibacillus periandrae, Paenibacillus vorticalis, Paenibacillus chartarius, Paenibacillus solisilvae, Paenibacillus turicensis, Paenibacillus zanthoxyli, Paenibacillus gallinarum, Paenibacillus prosopidis, Paenibacillus phocaensis, Paenibacillus dakarensis, Paenibacillus oenotherae, Paenibacillus thiaminolyticus, Paenibacillus curdlanolyticus, Paenibacillus marchantiae, Paenibacillus antarcticus, Paenibacillus dokdonensis, Paenibacillus koleovorans, Paenibacillus translucens, Paenibacillus pseudetheri, Paenibacillus tianmuensis, Paenibacillus tezpurensis, Paenibacillus auburnensis, Paenibacillus donghaensis, Paenibacillus turpanensis, Paenibacillus contaminans, Paenibacillus brasilensis, Paenibacillus flagellatus, Paenibacillus wooponensis, Paenibacillus endoradicis, Paenibacillus lycopersici, Paenibacillus ginsengagri, Paenibacillus fukuinensis, Paenibacillus qingshengii, Paenibacillus medicaginis, Paenibacillus yunnanensis, Paenibacillus doosanensis, Paenibacillus konkukensis, Paenibacillus triticisoli, Paenibacillus seodonensis, Paenibacillus anaericanus, Paenibacillus chinjuensis, Paenibacillus ginsengarvi, Paenibacillus agarexedens, Paenibacillus athensensis, Paenibacillus granivorans, Paenibacillus darwinianus, Paenibacillus motobuensis, Paenibacillus salinicaeni, Paenibacillus triticicola, Paenibacillus glycinicola, Paenibacillus montanisoli, Paenibacillus susongensis, Paenibacillus yonginensis, Paenibacillus albilobatus, Paenibacillus anseongense, Paenibacillus taiwanensis, Paenibacillus rubinfantis, Paenibacillus bryophyllum, Paenibacillus lentimorbus, Paenibacillus azoreducens, Paenibacillus konsidensis, Paenibacillus azotifigens, Paenibacillus aurantiacus, Paenibacillus andongensis, Paenibacillus rhizoplanae, Paenibacillus rhizophilus, Paenibacillus planticolens, Paenibacillus pasadenensis, Paenibacillus panaciterrae, Paenibacillus daejeonensis, Paenibacillus methanolicus, Paenibacillus qinlingensis, Paenibacillus solanacearum, Paenibacillus nebraskensis, Paenibacillus ourofinensis, Paenibacillus tepidiphilus, Paenibacillus plantiphilus, Paenibacillus xylanexedens, Paenibacillus provencensis, Paenibacillus radicibacter, Paenibacillus arenilitoris, Paenibacillus rhizovicinus, Paenibacillus vietnamensis, Paenibacillus pocheonensis, Paenibacillus xylanivorans, unclassified Paenibacillus, Paenibacillus woosongensis, Paenibacillus massiliensis, Paenibacillus lignilyticus, Paenibacillus alkaliterrae, Paenibacillus cisolokensis, Paenibacillus sacheonensis, Paenibacillus senegalensis, Paenibacillus hodogayensis, Paenibacillus beijingensis, Paenibacillus sambharensis, Paenibacillus kyungheensis, Paenibacillus endophyticus, Paenibacillus hamazuiensis, Paenibacillus dongdonensis, Paenibacillus nematophilus, Paenibacillus sonchi group, Paenibacillus crassostreae, Paenibacillus cf. polymyxa, Paenibacillus barengoltzii, Paenibacillus tianjinensis, Paenibacillus ginsengihumi, Paenibacillus abekawaensis, Paenibacillus phytohabitans, Paenibacillus xylanisolvens, Paenibacillus camerounensis, Paenibacillus macquariensis, Paenibacillus montaniterrae, Paenibacillus thailandensis, Paenibacillus campinasensis, Paenibacillus farraposensis, Paenibacillus lutimineralis, Paenibacillus pinistramenti, Paenibacillus oleatilyticus, Paenibacillus xylanilyticus, Paenibacillus taichungensis, Paenibacillus esterisolvens, Paenibacillus shenyangensis, Paenibacillus rhizosphaerae, Paenibacillus xinjiangensis, Paenibacillus yanchengensis, Paenibacillus wulumuqiensis, Paenibacillus artemisiicola, Paenibacillus agaridevorans, Paenibacillus relictisesami, Paenibacillus liaoningensis, Paenibacillus chungangensis, Paenibacillus puldeungensis, Paenibacillus barcinonensis, Paenibacillus dendritiformis, Paenibacillus shirakamiensis, Paenibacillus caseinilyticus, Paenibacillus sinopodophylli, Paenibacillus tengchongensis, Paenibacillus guangzhouensis, Paenibacillus glycanilyticus, Paenibacillus darangshiensis, Paenibacillus pectinilyticus, Paenibacillus chitinolyticus, Paenibacillus phyllosphaerae, Paenibacillus taohuashanense, Paenibacillus ginsengiterrae, Paenibacillus nasutitermitis, Paenibacillus alkalitolerans, Paenibacillus septentrionalis, Paenibacillus algorifonticola, Paenibacillus allorhizoplanae, Paenibacillus xylaniclasticus, Paenibacillus gelatinilyticus, Paenibacillus physcomitrellae, Paenibacillus marinisediminis, Paenibacillus baekrokdamisoli, Paenibacillus hemerocallicola, Paenibacillus xanthinilyticus, Paenibacillus oceanisediminis, Paenibacillus xanthanilyticus, Paenibacillus antibioticophila, Paenibacillus melissococcoides, Paenibacillus selenitireducens, Paenibacillus thermoaerophilus, Paenibacillus frigoriresistens, Paenibacillus rhizolycopersici, Paenibacillus cellulosilyticus, Paenibacillus xerothermodurans, Paenibacillus psychroresistens, Paenibacillus allorhizosphaerae, Candidatus Paenibacillus aerius, Paenibacillus naphthalenovorans, Paenibacillus cellulositrophicus, Candidatus Paenibacillus hominis, Paenibacillus marchantiophytorum, Paenibacillus bouchesdurhonensis, Paenibacillus polysaccharolyticus, Candidatus Paenibacillus infantis, Paenibacillus senegalimassiliensis, Candidatus Paenibacillus ilicicola, Candidatus Paenibacillus castillanus, Candidatus Paenibacillus mageritense, Candidatus Paenibacillus valencianus, Candidatus Paenibacillus pamplonensis, Candidatus Paenibacillus pericardicum, Candidatus Paenibacillus hispaniensis, Candidatus Paenibacillus intestinavium, Candidatus Paenibacillus guadalajarensis, Paenibacillus radicis (ex Xue et al. 2023), Paenibacillus cucumis (ex Ahn et al. 2014), Paenibacillus radicis (ex Gao et al. 2016), Paenibacillus cucumis (ex Kampfer et al. 2016)
Benzoic acid
Benzoic acid appears as a white crystalline solid. Slightly soluble in water. The primary hazard is the potential for environmental damage if released. Immediate steps should be taken to limit spread to the environment. Used to make other chemicals, as a food preservative, and for other uses.
Benzoic acid is a compound comprising a benzene ring core carrying a carboxylic acid substituent. It has a role as an antimicrobial food preservative, an EC 3.1.1.3 (triacylglycerol lipase) inhibitor, an EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor, a plant metabolite, a human xenobiotic metabolite, an algal metabolite and a drug allergen. It is a conjugate acid of a benzoate.
A fungistatic compound that is widely used as a food preservative. It is conjugated to GLYCINE in the liver and excreted as hippuric acid. As the sodium salt form, sodium benzoate is used as a treatment for urea cycle disorders due to its ability to bind amino acids. This leads to excretion of these amino acids and a decrease in ammonia levels. Recent research shows that sodium benzoate may be beneficial as an add-on therapy (1 gram/day) in schizophrenia. Total Positive and Negative Syndrome Scale scores dropped by 21\\\\\% compared to placebo.
Benzoic acid is a Nitrogen Binding Agent. The mechanism of action of benzoic acid is as an Ammonium Ion Binding Activity.
Benzoic acid, C6H5COOH, is a colourless crystalline solid and the simplest aromatic carboxylic acid. Benzoic acid occurs naturally free and bound as benzoic acid esters in many plant and animal species. Appreciable amounts have been found in most berries (around 0.05\\\\\%). Cranberries contain as much as 300-1300 mg free benzoic acid per kg fruit. Benzoic acid is a fungistatic compound that is widely used as a food preservative. It often is conjugated to glycine in the liver and excreted as hippuric acid. Benzoic acid is a byproduct of phenylalanine metabolism in bacteria. It is also produced when gut bacteria process polyphenols (from ingested fruits or beverages).
A fungistatic compound that is widely used as a food preservative. It is conjugated to GLYCINE in the liver and excreted as hippuric acid.
See also: Salicylic Acid (active moiety of); Benzoyl Peroxide (active moiety of); Sodium Benzoate (active moiety of) ... View More ...
Widespread in plants especies in essential oils and fruits, mostly in esterified formand is also present in butter, cooked meats, pork fat, white wine, black and green tea, mushroom and Bourbon vanilla. It is used in foodstuffs as antimicrobial and flavouring agent and as preservative. In practical food preservation, the Na salt of benzoic acid is the most widely used form (see
Indole-3-carboxaldehyde
Indole-3-carboxaldehyde (IAld or I3A), also known as 3-formylindole or 3-indolealdehyde, belongs to the class of organic compounds known as indoles. Indoles are compounds containing an indole moiety, which consists of a pyrrole ring fused to benzene to form 2,3-benzopyrrole. In humans, I3A is a biologically active metabolite which acts as a receptor agonist at the aryl hydrocarbon receptor in intestinal immune cells. It stimulates the production of interleukin-22 which facilitates mucosal reactivity (PMID:27102537). I3A is a microbially derived tryptophan metabolite produced by Clostridium and Lactobacillus (PMID:30120222, 27102537). I3A has also been found in the urine of patients with untreated phenylketonuria (PMID:5073866). I3A has been detected, but not quantified, in several different foods, such as beans, Brussels sprouts, cucumbers, cereals and cereal products, and white cabbages. This could make I3A a potential biomarker for the consumption of these foods. Indole-3-carbaldehyde is a heteroarenecarbaldehyde that is indole in which the hydrogen at position 3 has been replaced by a formyl group. It has a role as a plant metabolite, a human xenobiotic metabolite, a bacterial metabolite and a marine metabolite. It is a heteroarenecarbaldehyde, an indole alkaloid and a member of indoles. Indole-3-carboxaldehyde is a natural product found in Euphorbia hirsuta, Derris ovalifolia, and other organisms with data available. A heteroarenecarbaldehyde that is indole in which the hydrogen at position 3 has been replaced by a formyl group. Found in barley and tomato seedlings and cotton Indole-3-carboxaldehyde. CAS Common Chemistry. CAS, a division of the American Chemical Society, n.d. https://commonchemistry.cas.org/detail?cas_rn=487-89-8 (retrieved 2024-07-02) (CAS RN: 487-89-8). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0). Indole-3-carboxaldehyde (3-Formylindole), a banlangen extract, is the product of the oxidative degradation of indole-3-acetic acid (IAA) by crude enzyme preparations from etiolated pea seedlings. Indole-3-carboxaldehyde (3-Formylindole) is a biochemical used to prepare analogs of the indole phytoalexin cyclobrassinin[1]. Indole-3-carboxaldehyde (3-Formylindole), a banlangen extract, is the product of the oxidative degradation of indole-3-acetic acid (IAA) by crude enzyme preparations from etiolated pea seedlings. Indole-3-carboxaldehyde (3-Formylindole) is a biochemical used to prepare analogs of the indole phytoalexin cyclobrassinin[1].
2-Aminobenzoic acid
2-Aminobenzoic acid, also known as anthranilic acid or O-aminobenzoate, belongs to the class of organic compounds known as aminobenzoic acids. These are benzoic acids containing an amine group attached to the benzene moiety. Within humans, 2-aminobenzoic acid participates in a number of enzymatic reactions. In particular, 2-aminobenzoic acid and formic acid can be biosynthesized from formylanthranilic acid through its interaction with the enzyme kynurenine formamidase. In addition, 2-aminobenzoic acid and L-alanine can be biosynthesized from L-kynurenine through its interaction with the enzyme kynureninase. It is a substrate of enzyme 2-Aminobenzoic acid hydroxylase in benzoate degradation via hydroxylation pathway (KEGG). In humans, 2-aminobenzoic acid is involved in tryptophan metabolism. Outside of the human body, 2-Aminobenzoic acid has been detected, but not quantified in several different foods, such as mamey sapotes, prairie turnips, rowals, natal plums, and hyacinth beans. This could make 2-aminobenzoic acid a potential biomarker for the consumption of these foods. 2-Aminobenzoic acid is a is a tryptophan-derived uremic toxin with multidirectional properties that can affect the hemostatic system. Uremic syndrome may affect any part of the body and can cause nausea, vomiting, loss of appetite, and weight loss. Chronic exposure of uremic toxins can lead to a number of conditions including renal damage, chronic kidney disease and cardiovascular disease. It can also cause changes in mental status, such as confusion, reduced awareness, agitation, psychosis, seizures, and coma. 2-Aminobenzoic acid is an organic compound. It is a substrate of enzyme anthranilate hydroxylase [EC 1.14.13.35] in benzoate degradation via hydroxylation pathway (KEGG). [HMDB]. Anthranilic acid is found in many foods, some of which are butternut squash, sunflower, ginger, and hyssop. Acquisition and generation of the data is financially supported in part by CREST/JST. D002491 - Central Nervous System Agents > D000927 - Anticonvulsants CONFIDENCE standard compound; INTERNAL_ID 8844 CONFIDENCE standard compound; INTERNAL_ID 8009 CONFIDENCE standard compound; INTERNAL_ID 115 KEIO_ID A010
Tryptophol
Tryptophol, also known as indole-3-ethanol, is an indolyl alcohol that is ethanol substituted by a 1H-indol-3-yl group at position 2. It has a role as a Saccharomyces cerevisiae metabolite, an auxin and a plant metabolite. Tryptophol is a catabolite of tryptophan converted by the gut microbiota. After absorption through the intestinal epithelium, tryptophan catabolites enter the bloodstream and are later excreted in the urine (PMID:30120222). Tryptophol production was negatively associated with interferon-gamma production (IFNγ) which suggests that tryptophol has anti-inflammatory properties (PMID:27814509). Tryptophol has also been identified as the hypnotic agent in trypanosomal sleeping sickness, and because it is formed in vivo after ethanol or disulfiram treatment, it is also associated with the study of alcoholism (PMID:7241135). Indole-3-ethanol is a dietary indole present in cruciferous vegetables that has been shown to influence estradiol metabolism in humans and may provide a new chemopreventive approach to estrogen-dependent diseases. (PMID 2342128) Tryptophol. CAS Common Chemistry. CAS, a division of the American Chemical Society, n.d. https://commonchemistry.cas.org/detail?cas_rn=526-55-6 (retrieved 2024-06-29) (CAS RN: 526-55-6). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0). Tryptophol (Indole-3-ethanol) is an endogenous metabolite. Tryptophol (Indole-3-ethanol) is an endogenous metabolite.
Indoleacetic acid
Indoleacetic acid (IAA) is a breakdown product of tryptophan metabolism and is often produced by the action of bacteria in the mammalian gut. Higher levels of IAA are associated with bacteria from Clostridium species including C. stricklandii, C. lituseburense, C. subterminale, and C. putrefaciens (PMID: 12173102). IAA can be found in Agrobacterium, Azospirillum, Bacillus, Bradyrhizobium, Clostridium, Enterobacter, Pantoea, Pseudomonas, Rhizobium (PMID: 12173102, PMID: 17555270, PMID: 12147474, PMID: 19400643, PMID: 9450337, PMID: 21397014) (https://link.springer.com/chapter/10.1007/978-1-4612-3084-7_7) (https://escholarship.org/uc/item/1bf1b5m3). Some endogenous production of IAA in mammalian tissues also occurs. It may be produced by the decarboxylation of tryptamine or the oxidative deamination of tryptophan. IAA frequently occurs at low levels in urine and has been found in elevated levels in the urine of patients with phenylketonuria (PMID: 13610897). IAA has also been identified as a uremic toxin according to the European Uremic Toxin Working Group (PMID: 22626821). Using material extracted from human urine, it was discovered by Kogl in 1933 that indoleacetic acid is also an important plant hormone (PMID: 13610897). Specifically, IAA is a member of the group of phytohormones called auxins. IAA is generally considered to be the most important native auxin. Plant cells synthesize IAA from tryptophan (Wikipedia). IAA and some derivatives can be oxidized by horseradish peroxidase (HRP) into cytotoxic species. IAA is only toxic after oxidative decarboxylation; the effect of IAA/HRP is thought to be due in part to the formation of methylene-oxindole, which may conjugate with DNA bases and protein thiols. IAA/HRP could be used as the basis for targeted cancer, a potential new role for plant auxins in cancer therapy (PMID: 11163327). 1h-indol-3-ylacetic acid, also known as (indol-3-yl)acetate or heteroauxin, belongs to indole-3-acetic acid derivatives class of compounds. Those are compounds containing an acetic acid (or a derivative) linked to the C3 carbon atom of an indole. 1h-indol-3-ylacetic acid is slightly soluble (in water) and a weakly acidic compound (based on its pKa). 1h-indol-3-ylacetic acid is a mild, odorless, and sour tasting compound and can be found in a number of food items such as sweet bay, chinese bayberry, winter squash, and linden, which makes 1h-indol-3-ylacetic acid a potential biomarker for the consumption of these food products. 1h-indol-3-ylacetic acid can be found primarily in most biofluids, including blood, feces, saliva, and urine, as well as throughout most human tissues. 1h-indol-3-ylacetic acid exists in all living species, ranging from bacteria to humans. In humans, 1h-indol-3-ylacetic acid is involved in the tryptophan metabolism. Moreover, 1h-indol-3-ylacetic acid is found to be associated with appendicitis and irritable bowel syndrome. 1h-indol-3-ylacetic acid is a non-carcinogenic (not listed by IARC) potentially toxic compound. Chronic Exposure: Kidney dialysis is usually needed to relieve the symptoms of uremic syndrome until normal kidney function can be restored. CONFIDENCE standard compound; INTERNAL_ID 190; DATASET 20200303_ENTACT_RP_MIX501; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3375; ORIGINAL_PRECURSOR_SCAN_NO 3371 CONFIDENCE standard compound; INTERNAL_ID 190; DATASET 20200303_ENTACT_RP_MIX501; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3366; ORIGINAL_PRECURSOR_SCAN_NO 3363 CONFIDENCE standard compound; INTERNAL_ID 190; DATASET 20200303_ENTACT_RP_MIX501; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3365; ORIGINAL_PRECURSOR_SCAN_NO 3361 CONFIDENCE standard compound; INTERNAL_ID 190; DATASET 20200303_ENTACT_RP_MIX501; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3395; ORIGINAL_PRECURSOR_SCAN_NO 3391 DATA_PROCESSING MERGING RMBmix ver. 0.2.7; CONFIDENCE standard compound; INTERNAL_ID 190; DATASET 20200303_ENTACT_RP_MIX501; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3366; ORIGINAL_PRECURSOR_SCAN_NO 3363 CONFIDENCE standard compound; INTERNAL_ID 190; DATASET 20200303_ENTACT_RP_MIX501; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3369; ORIGINAL_PRECURSOR_SCAN_NO 3366 CONFIDENCE standard compound; INTERNAL_ID 190; DATASET 20200303_ENTACT_RP_MIX501; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3385; ORIGINAL_PRECURSOR_SCAN_NO 3380 D006133 - Growth Substances > D010937 - Plant Growth Regulators > D007210 - Indoleacetic Acids Acquisition and generation of the data is financially supported in part by CREST/JST. IPB_RECORD: 275; CONFIDENCE confident structure CONFIDENCE standard compound; INTERNAL_ID 2796 CONFIDENCE standard compound; INTERNAL_ID 166 COVID info from COVID-19 Disease Map Corona-virus KEIO_ID I038 Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS 3-Indoleacetic acid (Indole-3-acetic acid) is the most common natural plant growth hormone of the auxin class. It can be added to cell culture medium to induce plant cell elongation and division. 3-Indoleacetic acid (Indole-3-acetic acid) is the most common natural plant growth hormone of the auxin class. It can be added to cell culture medium to induce plant cell elongation and division.
Indole-3-lactic acid
Indolelactic acid (CAS: 1821-52-9) is a tryptophan metabolite found in human plasma, serum, and urine. Tryptophan is metabolized by two major pathways in humans, either through kynurenine or via a series of indoles, and some of its metabolites are known to be biologically active. Indolelactic acid is present in various amounts, significantly higher in umbilical fetal plasma than in maternal plasma in the protein-bound form (PMID 2361979, 1400722, 3597614, 11060358, 1400722). Indolelactic acid is also a microbial metabolite; urinary indole-3-lactate is produced by Clostridium sporogenes (PMID: 29168502). Indolelactic acid is a tryptophan metabolite found in human plasma and serum and normal urine. Tryptophan is metabolized by two major pathways in humans, either through kynurenine or via a series of indoles, and some of its metabolites are known to be biologically active. Indolelactic acid is present in various amounts, significantly higher in umbilical foetal plasma than in maternal plasma in the protein-bound form. (PMID 2361979, 1400722, 3597614, 11060358, 1400722) [HMDB] Indolelactic acid (Indole-3-lactic acid) is a tryptophan (Trp) catabolite in Azotobacter vinelandii cultures. Indolelactic acid has anti-inflammation and potential anti-viral activity[1][3][4].
Indole-3-carboxylic acid
Indole-3-carboxylic acid, also known as 3-carboxyindole or 3-indolecarboxylate, belongs to the class of organic compounds known as indolecarboxylic acids and derivatives. Indolecarboxylic acids and derivatives are compounds containing a carboxylic acid group (or a derivative thereof) linked to an indole. Naphthylmethylindoles: Any compound containing a 1H-indol-3-yl-(1-naphthyl)methane structure with substitution at the nitrogen atom of the indole ring by an alkyl, haloalkyl, alkenyl, cycloalkylmethyl, cycloalkylethyl, 1-(N-methyl-2-piperidinyl)methyl, or 2-(4-morpholinyl)ethyl group whether or not further substituted in the indole ring to any extent and whether or not substituted in the naphthyl ring to any extent. One example given is JWH-250. Outside of the human body, indole-3-carboxylic acid has been detected, but not quantified in several different foods, such as brassicas, broccoli, pulses, common beets, and barley. This could make indole-3-carboxylic acid a potential biomarker for the consumption of these foods. Notice the pentyl group substituted onto the nitrogen atom of the indole ring. Note that this definition encompasses only those compounds that have OH groups attached to both the phenyl and the cyclohexyl rings, and so does not include compounds such as O-1871 which lacks the cyclohexyl OH group, or compounds such as JWH-337 or JWH-344 which lack the phenolic OH group. Present in plants, e.g. apple (Pyrus malus), garden pea (Pisum sativum) and brassicas Indole-3-carboxylic acid is a normal urinary indolic tryptophan metabolite and has been found elevated in patients with liver diseases[1][2]. Indole-3-carboxylic acid is a normal urinary indolic tryptophan metabolite and has been found elevated in patients with liver diseases[1][2].
Indole
Indole is an aromatic heterocyclic organic compound. It has a bicyclic structure, consisting of a six-membered benzene ring fused to a five-membered nitrogen-containing pyrrole ring. The participation of the nitrogen lone electron pair in the aromatic ring means that indole is not a base, and it does not behave like a simple amine. Indole is a microbial metabolite and it can be produced by bacteria as a degradation product of the amino acid tryptophan. It occurs naturally in human feces and has an intense fecal smell. At very low concentrations, however, indole has a flowery smell and is a constituent of many flower scents (such as orange blossoms) and perfumes. As a volatile organic compound, indole has been identified as a fecal biomarker of Clostridium difficile infection (PMID: 30986230). Natural jasmine oil, used in the perfume industry, contains around 2.5\\\\\% of indole. Indole also occurs in coal tar. Indole has been found to be produced in a number of bacterial genera including Alcaligenes, Aspergillus, Escherichia, and Pseudomonas (PMID: 23194589, 2310183, 9680309). Indole plays a role in bacterial biofilm formation, bacterial motility, bacterial virulence, plasmid stability, and antibiotic resistance. It also functions as an intercellular signalling molecule (PMID: 26115989). Recently, it was determined that the bacterial membrane-bound histidine sensor kinase (HK) known as CpxA acts as a bacterial indole sensor to facilitate signalling (PMID: 31164470). It has been found that decreased indole concentrations in the gut promote bacterial pathogenesis, while increased levels of indole in the gut decrease bacterial virulence gene expression (PMID: 31164470). As a result, enteric pathogens sense a gradient of indole concentrations in the gut to migrate to different niches and successfully establish an infection. Constituent of several flower oils, especies of Jasminum and Citrus subspecies (Oleaceae) production of bacterial dec. of proteins. Flavouring ingredientand is also present in crispbread, Swiss cheese, Camembert cheese, wine, cocoa, black and green tea, rum, roasted filbert, rice bran, clary sage, raw shrimp and other foodstuffs Indole. CAS Common Chemistry. CAS, a division of the American Chemical Society, n.d. https://commonchemistry.cas.org/detail?cas_rn=120-72-9 (retrieved 2024-07-16) (CAS RN: 120-72-9). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0). Indole is an endogenous metabolite. Indole is an endogenous metabolite.
Indole-3-acetamide
Indole-3-acetamide, also known as 2-(3-indolyl)acetamide or IAM, belongs to the class of organic compounds known as 3-alkylindoles. 3-Alkylindoles are compounds containing an indole moiety that carries an alkyl chain at the 3-position. Indole-3-acetamide has been detected, but not quantified, in several different foods, such as Alaska wild rhubarbs, lingonberries, butternut squash, pineapples, and agaves. Indole-3-acetamide is also found in the common pea and has been isolated from the etiolated seedlings of the black gram (Phaseolus mungo). Isolated from etiolated seedlings of the black gram (Phaseolus mungo). 1H-Indole-3-acetamide is found in many foods, some of which are elderberry, barley, american cranberry, and herbs and spices. D006133 - Growth Substances > D010937 - Plant Growth Regulators > D007210 - Indoleacetic Acids KEIO_ID I030 Indole-3-acetamide is a biosynthesis intermediate of indole-3-acetic acid (HY-18569). Indole-3-acetic acid is the most common natural plant growth hormone of the auxin class[1].
1-Deoxynojirimycin
1-Deoxynojirimycin is found in fruits. 1-Deoxynojirimycin is an alkaloid from Morus specie Alkaloid from Morus subspecies 1-Deoxynojirimycin is found in fruits. Same as: D09605 1-Deoxynojirimycin (Duvoglustat) is a potent and orally active α-glucosidase inhibitor. 1-Deoxynojirimycin suppresses postprandial blood glucose and is widely used for diabetes mellitus. 1-Deoxynojirimycin possesses antihyperglycemic, anti-obesity, and antiviral features[1][2]. 1-Deoxynojirimycin (Duvoglustat) is a potent and orally active α-glucosidase inhibitor. 1-Deoxynojirimycin suppresses postprandial blood glucose and is widely used for diabetes mellitus. 1-Deoxynojirimycin possesses antihyperglycemic, anti-obesity, and antiviral features[1][2].
Polymyxin B Sulfate
Polymyxin B sulfate is a mixture of polymyxins B1 and B2, obtained from Bacillus polymyxa strains. They are basic polypeptides of about eight amino acids and have cationic detergent action on cell membranes. Polymyxin B is used for infections with gram-negative organisms, but may be neurotoxic and nephrotoxic. All gram-positive bacteria, fungi, and the gram-negative cocci, N. gonorrhea and N. menigitidis, are resistant. It is appropriate for treatment of infections of the urinary tract, meninges, and blood stream, caused by susceptible strains of Pseudomonas aeruginosa. D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D011113 - Polymyxins D000890 - Anti-Infective Agents > D023181 - Antimicrobial Cationic Peptides
Indoleacetic acid
D006133 - Growth Substances > D010937 - Plant Growth Regulators > D007210 - Indoleacetic Acids COVID info from COVID-19 Disease Map Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS 3-Indoleacetic acid (Indole-3-acetic acid) is the most common natural plant growth hormone of the auxin class. It can be added to cell culture medium to induce plant cell elongation and division. 3-Indoleacetic acid (Indole-3-acetic acid) is the most common natural plant growth hormone of the auxin class. It can be added to cell culture medium to induce plant cell elongation and division.
1H-Indole-3-carboxylic acid
IPB_RECORD: 302; CONFIDENCE confident structure CONFIDENCE confident structure; IPB_RECORD: 302
3-Indolecarboxylic acid
An indole-3-carboxylic acid carrying a carboxy group at position 3. Acquisition and generation of the data is financially supported in part by CREST/JST. IPB_RECORD: 2301; CONFIDENCE confident structure Indole-3-carboxylic acid is a normal urinary indolic tryptophan metabolite and has been found elevated in patients with liver diseases[1][2]. Indole-3-carboxylic acid is a normal urinary indolic tryptophan metabolite and has been found elevated in patients with liver diseases[1][2].
3-Indoleacetic acid
A monocarboxylic acid that is acetic acid in which one of the methyl hydrogens has been replaced by a 1H-indol-3-yl group. D006133 - Growth Substances > D010937 - Plant Growth Regulators > D007210 - Indoleacetic Acids COVID info from COVID-19 Disease Map Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS MS2 deconvoluted using MS2Dec from all ion fragmentation data, MetaboLights identifier MTBLS1040; SEOVTRFCIGRIMH-UHFFFAOYSA-N_STSL_0200_3-Indoleacetic Acid_2000fmol_180831_S2_L02M02_62; Spectrum acquired as described in Naz et al 2017 PMID 28641411. Preparation and submission to MassBank of North America by Chaleckis R. and Tada I. MS2 deconvoluted using CorrDec from all ion fragmentation data, MetaboLights identifier MTBLS1040; Spectrum acquired as described in Naz et al 2017 PMID 28641411. Preparation and submission to MassBank of North America by Chaleckis R. and Tada I. 3-Indoleacetic acid (Indole-3-acetic acid) is the most common natural plant growth hormone of the auxin class. It can be added to cell culture medium to induce plant cell elongation and division. 3-Indoleacetic acid (Indole-3-acetic acid) is the most common natural plant growth hormone of the auxin class. It can be added to cell culture medium to induce plant cell elongation and division.
Tryptophol
An indolyl alcohol that is ethanol substituted by a 1H-indol-3-yl group at position 2. Tryptophol (Indole-3-ethanol) is an endogenous metabolite. Tryptophol (Indole-3-ethanol) is an endogenous metabolite.
Anthranilic acid
An aminobenzoic acid that is benzoic acid having a single amino substituent located at position 2. It is a metabolite produced in L-tryptophan-kynurenine pathway in the central nervous system. D002491 - Central Nervous System Agents > D000927 - Anticonvulsants
Indole-3-carboxaldehyde
Indole-3-carboxaldehyde (3-Formylindole), a banlangen extract, is the product of the oxidative degradation of indole-3-acetic acid (IAA) by crude enzyme preparations from etiolated pea seedlings. Indole-3-carboxaldehyde (3-Formylindole) is a biochemical used to prepare analogs of the indole phytoalexin cyclobrassinin[1]. Indole-3-carboxaldehyde (3-Formylindole), a banlangen extract, is the product of the oxidative degradation of indole-3-acetic acid (IAA) by crude enzyme preparations from etiolated pea seedlings. Indole-3-carboxaldehyde (3-Formylindole) is a biochemical used to prepare analogs of the indole phytoalexin cyclobrassinin[1].
Benzoic Acid
Benzoic acid is an aromatic alcohol existing naturally in many plants and is a common additive to food, drinks, cosmetics and other products. It acts as preservatives through inhibiting both bacteria and fungi. Benzoic acid is an aromatic alcohol existing naturally in many plants and is a common additive to food, drinks, cosmetics and other products. It acts as preservatives through inhibiting both bacteria and fungi.
indole-3-acetamide
A member of the class of indoles that is acetamide substituted by a 1H-indol-3-yl group at position 2. It is an intermediate in the production of plant hormone indole acetic acid (IAA). D006133 - Growth Substances > D010937 - Plant Growth Regulators > D007210 - Indoleacetic Acids Indole-3-acetamide is a biosynthesis intermediate of indole-3-acetic acid (HY-18569). Indole-3-acetic acid is the most common natural plant growth hormone of the auxin class[1].
2-aminobenzoic acid
MS2 deconvoluted using MS2Dec from all ion fragmentation data, MetaboLights identifier MTBLS1040; RWZYAGGXGHYGMB-UHFFFAOYSA-N_STSL_0017_Anthranilic Acid_8000fmol_180410_S2_LC02_MS02_91; Spectrum acquired as described in Naz et al 2017 PMID 28641411. Preparation and submission to MassBank of North America by Chaleckis R. and Tada I. MS2 deconvoluted using CorrDec from all ion fragmentation data, MetaboLights identifier MTBLS1040; Spectrum acquired as described in Naz et al 2017 PMID 28641411. Preparation and submission to MassBank of North America by Chaleckis R. and Tada I.
771-50-6
Indole-3-carboxylic acid is a normal urinary indolic tryptophan metabolite and has been found elevated in patients with liver diseases[1][2]. Indole-3-carboxylic acid is a normal urinary indolic tryptophan metabolite and has been found elevated in patients with liver diseases[1][2].
AI3-52407
Indole-3-carboxaldehyde (3-Formylindole), a banlangen extract, is the product of the oxidative degradation of indole-3-acetic acid (IAA) by crude enzyme preparations from etiolated pea seedlings. Indole-3-carboxaldehyde (3-Formylindole) is a biochemical used to prepare analogs of the indole phytoalexin cyclobrassinin[1]. Indole-3-carboxaldehyde (3-Formylindole), a banlangen extract, is the product of the oxidative degradation of indole-3-acetic acid (IAA) by crude enzyme preparations from etiolated pea seedlings. Indole-3-carboxaldehyde (3-Formylindole) is a biochemical used to prepare analogs of the indole phytoalexin cyclobrassinin[1].
3-IAA
D006133 - Growth Substances > D010937 - Plant Growth Regulators > D007210 - Indoleacetic Acids COVID info from COVID-19 Disease Map Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS 3-Indoleacetic acid (Indole-3-acetic acid) is the most common natural plant growth hormone of the auxin class. It can be added to cell culture medium to induce plant cell elongation and division. 3-Indoleacetic acid (Indole-3-acetic acid) is the most common natural plant growth hormone of the auxin class. It can be added to cell culture medium to induce plant cell elongation and division.
Indole-3-lactic Acid
Indolelactic acid (Indole-3-lactic acid) is a tryptophan (Trp) catabolite in Azotobacter vinelandii cultures. Indolelactic acid has anti-inflammation and potential anti-viral activity[1][3][4].
