Exact Mass: 472.3301
Exact Mass Matches: 472.3301
Found 500 metabolites which its exact mass value is equals to given mass value 472.3301,
within given mass tolerance error 0.05 dalton. Try search metabolite list with more accurate mass tolerance error
0.01 dalton.
Echinocystic
Echinocystic acid is a triterpenoid. Echinocystic acid is a natural product found in Cucurbita foetidissima, Eclipta alba, and other organisms with data available. Echinocystic acid is a pentacyclic triterpene extracted from the fruit of Honey Locust. It has strong antioxidant, anti-inflammatory and anti-tumor properties. Echinocystic acid is a pentacyclic triterpene extracted from the fruit of Honey Locust. It has strong antioxidant, anti-inflammatory and anti-tumor properties.
Maslinic acid
Maslinic acid is a compound derived from dry olive-pomace oil (an olive skin wax) which is a byproduct of olive oil extraction. It is a member of the group of triterpenes known as oleananes.; Maslinic acid is a pentacyclic triterpene, found in the non-glyceride fraction of olive pomace oil (Olive pomace oil, also known as "orujo" olive oil, is a blend of refined-pomace oil and virgin olive oil, fit for human consumption). Pentacyclic triterpenes are natural compounds which are widely distributed in plants. These natural products have been demonstrated to possess anti-inflammatory properties. Triterpenoids have been reported to possess antioxidant properties, since they prevent lipid peroxidation and suppress superoxide anion generation. The triterpenes have a history of medicinal use in many Asian countries. Maslinic acid exhibits both pro- and anti-inflammatory properties depending on chemical structure and dose and may be useful in modulating the immune response; further studies are required to confirm the immunomodulatory behaviour of this triterpenoid, and characterise the mechanisms underlying the biphasic nature of some aspects of the inflammatory response. (PMID: 17292619) Maslinic acid is a pentacyclic triterpene, found in the non-glyceride fraction of olive pomace oil (Olive pomace oil, also known as "orujo" olive oil, is a blend of refined-pomace oil and virgin olive oil, fit for human consumption). Pentacyclic triterpenes are natural compounds which are widely distributed in plants. These natural products have been demonstrated to possess anti-inflammatory properties. Triterpenoids have been reported to possess antioxidant properties, since they prevent lipid peroxidation and suppress superoxide anion generation. The triterpenes have a history of medicinal use in many Asian countries. Maslinic acid exhibits both pro- and anti-inflammatory properties depending on chemical structure and dose and may be useful in modulating the immune response; further studies are required to confirm the immunomodulatory behaviour of this triterpenoid, and characterise the mechanisms underlying the biphasic nature of some aspects of the inflammatory response. (PMID: 17292619). Maslinic acid is a pentacyclic triterpenoid that is olean-12-ene substituted by hydroxy groups at positions 2 and 3 and a carboxy group at position 28 (the 2alpha,3beta stereoisomer). It is isolated from Olea europaea and Salvia canariensis and exhibits anti-inflammatory, antioxidant and antineoplastic activity. It has a role as an antioxidant, an antineoplastic agent, an anti-inflammatory agent and a plant metabolite. It is a pentacyclic triterpenoid and a dihydroxy monocarboxylic acid. It derives from a hydride of an oleanane. Maslinic acid is a natural product found in Chaenomeles speciosa, Salvia tomentosa, and other organisms with data available. See also: Centaurium erythraea whole (part of). A pentacyclic triterpenoid that is olean-12-ene substituted by hydroxy groups at positions 2 and 3 and a carboxy group at position 28 (the 2alpha,3beta stereoisomer). It is isolated from Olea europaea and Salvia canariensis and exhibits anti-inflammatory, antioxidant and antineoplastic activity. Maslinic acid can inhibit the DNA-binding activity of NF-κB p65 and abolish the phosphorylation of IκB-α, which is required for p65 activation. Maslinic acid can inhibit the DNA-binding activity of NF-κB p65 and abolish the phosphorylation of IκB-α, which is required for p65 activation.
Alisol
Alisol B is a triterpenoid. Alisol B is a natural product found in Alisma, Alisma plantago-aquatica, and other organisms with data available. Alisol B is a potentially novel therapeutic compound for bone disorders by targeting the differentiation of osteoclasts as well as their functions. IC50 Value: Target: In vitro: The in vitro cultured human renal tubular epithelial HK-2 cells were intervened with 5 ng/mL transforming growth factor-beta (TGF-beta), 0.1 micromol C3a, and 0.1 micromol C3a + 10 micromol alisol B, respectively. Exogenous C3a could induce renal tubular EMT. Alisol B was capable of suppressing C3a induced EMT [1]. Alisol-B strongly inhibited RANKL-induced osteoclast formation when added during the early stage of cultures, suggesting that alisol-B acts on osteoclast precursors to inhibit RANKL/RANK signaling. Among the RANK signaling pathways, alisol-B inhibited the phosphorylation of JNK, which are upregulated in response to RANKL in bone marrow macrophages, alisol-B also inhibited RANKL-induced expression of NFATc1 and c-Fos, which are key transcription factors for osteoclastogenesis. In addition, alisol-B suppressed the pit-forming activity and disrupted the actin ring formation of mature osteoclasts [2]. Alisol B induced calcium mobilization from internal stores, leading to autophagy through the activation of the CaMKK-AMPK-mammalian target of rapamycin pathway. Moreover, the disruption of calcium homeostasis induces endoplasmic reticulum stress and unfolded protein responses in alisol B-treated cells, leading to apoptotic cell death. Finally, by computational virtual docking analysis and biochemical assays, it was showed that the molecular target of alisol B is the sarcoplasmic/endoplasmic reticulum Ca(2+) ATPase [3]. In vivo: Alisol B is a potentially novel therapeutic compound for bone disorders by targeting the differentiation of osteoclasts as well as their functions. IC50 Value: Target: In vitro: The in vitro cultured human renal tubular epithelial HK-2 cells were intervened with 5 ng/mL transforming growth factor-beta (TGF-beta), 0.1 micromol C3a, and 0.1 micromol C3a + 10 micromol alisol B, respectively. Exogenous C3a could induce renal tubular EMT. Alisol B was capable of suppressing C3a induced EMT [1]. Alisol-B strongly inhibited RANKL-induced osteoclast formation when added during the early stage of cultures, suggesting that alisol-B acts on osteoclast precursors to inhibit RANKL/RANK signaling. Among the RANK signaling pathways, alisol-B inhibited the phosphorylation of JNK, which are upregulated in response to RANKL in bone marrow macrophages, alisol-B also inhibited RANKL-induced expression of NFATc1 and c-Fos, which are key transcription factors for osteoclastogenesis. In addition, alisol-B suppressed the pit-forming activity and disrupted the actin ring formation of mature osteoclasts [2]. Alisol B induced calcium mobilization from internal stores, leading to autophagy through the activation of the CaMKK-AMPK-mammalian target of rapamycin pathway. Moreover, the disruption of calcium homeostasis induces endoplasmic reticulum stress and unfolded protein responses in alisol B-treated cells, leading to apoptotic cell death. Finally, by computational virtual docking analysis and biochemical assays, it was showed that the molecular target of alisol B is the sarcoplasmic/endoplasmic reticulum Ca(2+) ATPase [3]. In vivo:
Alphitolsaure
2alpha,3beta-dihydroxy-20(29)-lupen-28-oic acid is a pentacyclic triterpenoid that is betulinic acid carrying an additional alpha-hydroxy group at position 2. It has been isolated from Breynia fruticosa. It has a role as a plant metabolite. It is a pentacyclic triterpenoid and a dihydroxy monocarboxylic acid. It is functionally related to a betulinic acid. It derives from a hydride of a lupane. Alphitolic acid is a natural product found in Quercus aliena, Alphitonia petriei, and other organisms with data available. A pentacyclic triterpenoid that is betulinic acid carrying an additional alpha-hydroxy group at position 2. It has been isolated from Breynia fruticosa.
Corosolic acid
Colosolic acid is a natural product found in Rhododendron brachycarpum, Psidium, and other organisms with data available.
Pomolic acid
Constituent of apple peel. Pomolic acid is found in many foods, some of which are rosemary, lemon balm, pomes, and spearmint. Pomolic acid is found in apple. Pomolic acid is a constituent of apple peel Randialic acid A (Pomolic acid) is a pentacyclic triterpene isolated from?Euscaphis japonica?(Tunb.). Randialic acid A (Pomolic acid) inhibits tumor cells growth and induces cell apoptosis. Randialic acid A (Pomolic acid) has a potential for the treatment of prostate cancer (PC)[2]. Randialic acid A (Pomolic acid) is a pentacyclic triterpene isolated from?Euscaphis japonica?(Tunb.). Randialic acid A (Pomolic acid) inhibits tumor cells growth and induces cell apoptosis. Randialic acid A (Pomolic acid) has a potential for the treatment of prostate cancer (PC)[2].
Sebiferenic acid
Sebiferenic acid is found in fats and oils. Sebiferenic acid is a constituent of Sapium sebiferum (Chinese tallowtree) Constituent of Sapium sebiferum (Chinese tallowtree). Sebiferenic acid is found in fats and oils.
(3b,22S,24E)-3,22-Dihydroxycycloart-24-en-26-oic acid
(3b,22S,24E)-3,22-Dihydroxycycloart-24-en-26-oic acid is found in fruits. (3b,22S,24E)-3,22-Dihydroxycycloart-24-en-26-oic acid is a constituent of Mangifera indica (mango)
Lucidumol A
Lucidumol A is found in mushrooms. Lucidumol A is a constituent of Ganoderma lucida (reishi). Constituent of Ganoderma lucida (reishi). Lucidumol A is found in mushrooms.
Methyl (7Z,9Z,9'Z)-6'-apo-y-caroten-6'-oate
Methyl (7Z,9Z,9Z)-6-apo-y-caroten-6-oate is isolated from the seeds of Bixa orellana (annatto). Constituent of the seeds of Bixa orellana (annatto).
(3beta,17alpha,23R)-17,23-Epoxy-3,29-dihydroxy-27-norlanost-8-ene-15,24-dione
(3beta,17alpha,23R)-17,23-Epoxy-3,29-dihydroxy-27-norlanost-8-ene-15,24-dione is found in herbs and spices. (3beta,17alpha,23R)-17,23-Epoxy-3,29-dihydroxy-27-norlanost-8-ene-15,24-dione is a constituent of Muscari comosum (tassel hyacinth)
Ganodermanontriol
Ganodermanontriol is found in mushrooms. Ganodermanontriol is a constituent of Ganoderma lucidum (reishi) Constituent of Ganoderma lucidum (reishi). Ganodermanontriol is found in mushrooms.
20beta-Hydroxyursolic acid
20beta-Hydroxyursolic acid is found in pomes. 20beta-Hydroxyursolic acid is a constituent of apple skin and elder blossoms Constituent of apple skin and elder blossoms. 20beta-Hydroxyursolic acid is found in pomes and black elderberry.
Queretaroic acid
Queretaroic acid is found in cereals and cereal products. Queretaroic acid is a constituent of Chenopodium quinoa (quinoa), Stenocereus thurberi (organ pipe cactus) Constituent of Chenopodium quinoa (quinoa), Stenocereus thurberi (organ pipe cactus). Queretaroic acid is found in cereals and cereal products and fruits.
Ganoderiol E
Ganoderiol E is found in mushrooms. Ganoderiol E is a metabolite of Ganoderma lucidum (reishi). Metabolite of Ganoderma lucidum (reishi). Ganoderiol E is found in mushrooms.
Reticulataxanthin
Reticulataxanthin is found in citrus. Peel constituent of tangerine (Citrus reticulata) and the tangerine hybrid (Minneola tangor). Peel constituent of tangerine (Citrus reticulata) and the tangerine hybrid (Minneola tangor). Reticulataxanthin is found in citrus.
27-Hydroxyisomangiferolic acid
27-Hydroxymangiferolic acid is found in fruits. 27-Hydroxymangiferolic acid is a constituent of the stem bark of Mangifera indica (mango).
Azukisapogenol
Azukisapogenol is found in adzuki bean. Azukisapogenol is isolated from Vigna angularis (azuki bean). Isolated from Vigna angularis (azuki bean). Azukisapogenol is found in pulses and adzuki bean.
Rubitic acid
Rubitic acid is found in fruits. Rubitic acid is a constituent of Rubus fruticosus (blackberry). Constituent of Rubus fruticosus (blackberry). Rubitic acid is found in fruits.
Momordicin I
Momordicin I is found in bitter gourd. Momordicin I is a constituent of leaves and vines of Momordica charantia (bitter melon)
Ganoderic acid U
Ganoderic acid U is found in mushrooms. Ganoderic acid U is a constituent of Ganoderma lucidum (reishi) Constituent of Ganoderma lucidum (reishi). Ganoderic acid U is found in mushrooms.
(3beta,23xi)-3,23-Dihydroxycycloart-24-en-26-oic acid
(3beta,23xi)-3,23-Dihydroxycycloart-24-en-26-oic acid is found in fruits. (3beta,23xi)-3,23-Dihydroxycycloart-24-en-26-oic acid is a constituent of Mangifera indica (mango)
3alpha-Corosolic acid
3alpha-Corosolic acid is found in herbs and spices. 3alpha-Corosolic acid is a constituent of Boswellia serrata (Indian olibanum). Constituent of Boswellia serrata (Indian olibanum). (2a,3a)-Dihydroxy-12-ursen-24-oic acid is found in herbs and spices.
Priverogenin A
Sapogenin from Primula veris (cowslip). Priverogenin A is found in tea and herbs and spices. Priverogenin A is found in herbs and spices. Sapogenin from Primula veris (cowslip
(17alpha,23S)-Epoxy-28,29-dihydroxy-27-norlanost-8-ene-3,24-dione
Aglycone from Muscari comosum (tassel hyacinth). (17alpha,23S)-Epoxy-28,29-dihydroxy-27-norlanost-8-ene-3,24-dione is found in herbs and spices. (17alpha,23S)-Epoxy-28,29-dihydroxy-27-norlanost-8-ene-3,24-dione is found in herbs and spices. Aglycone from Muscari comosum (tassel hyacinth
Albigenic acid
Albigenic acid is found in fats and oils. Albigenic acid is a constituent of Codonopsis lanceolata (todok) and from Helianthus annuus (sunflower). Constituent of Codonopsis lanceolata (todok) and from Helianthus annuus (sunflower). Albigenic acid is found in fats and oils.
delta-Maslinic acid
delta-Maslinic acid is found in fruits. delta-Maslinic acid is isolated from leaves of Olea europaea (olive). Isolated from leaves of Olea europaea (olive). delta-Maslinic acid is found in fruits.
(23S,24S)-17,23-Epoxy-24,29-dihydroxy-27-norlanost-8-ene-3,15-dione
(23S,24S)-17,23-Epoxy-24,29-dihydroxy-27-norlanost-8-ene-3,15-dione is found in herbs and spices. (23S,24S)-17,23-Epoxy-24,29-dihydroxy-27-norlanost-8-ene-3,15-dione is a constituent of Muscari comosum (tassel hyacinth) Constituent of Muscari comosum (tassel hyacinth). (23S,24S)-17,23-Epoxy-24,29-dihydroxy-27-norlanost-8-ene-3,15-dione is found in herbs and spices.
Epoxyganoderiol A
Epoxyganoderiol A is found in mushrooms. Epoxyganoderiol A is a metabolite of Ganoderma lucidum (reishi Metabolite of Ganoderma lucidum (reishi). Epoxyganoderiol A is found in mushrooms.
23-Hydroxybetulinic acid
Bredemolic acid
Corosolic acid
Corosolic acid, also known as corosolate, is a member of the class of compounds known as triterpenoids. Triterpenoids are terpene molecules containing six isoprene units. Corosolic acid is practically insoluble (in water) and a weakly acidic compound (based on its pKa). Corosolic acid can be found in guava, loquat, and olive, which makes corosolic acid a potential biomarker for the consumption of these food products. Corosolic acid is a pentacyclic triterpene acid found in Lagerstroemia speciosa. It is similar in structure to ursolic acid, differing only in the fact that it has a 2-alpha-hydroxy attachment . Corosolic acid (Colosolic acid) isolated from the fruit of Cratoegus pinnatifida var. psilosa, was reported to have anticancer activity. Corosolic acid (Colosolic acid) isolated from the fruit of Cratoegus pinnatifida var. psilosa, was reported to have anticancer activity.
Echinocystic acid
Echinocystic acid, also known as echinocystate, is a member of the class of compounds known as triterpenoids. Triterpenoids are terpene molecules containing six isoprene units. Echinocystic acid is practically insoluble (in water) and a weakly acidic compound (based on its pKa). Echinocystic acid can be found in sunflower, which makes echinocystic acid a potential biomarker for the consumption of this food product. Echinocystic acid is a pentacyclic triterpene extracted from the fruit of Honey Locust. It has strong antioxidant, anti-inflammatory and anti-tumor properties. Echinocystic acid is a pentacyclic triterpene extracted from the fruit of Honey Locust. It has strong antioxidant, anti-inflammatory and anti-tumor properties.
Hederagenin
Hederagenin is a member of the class of compounds known as triterpenoids. Triterpenoids are terpene molecules containing six isoprene units. Hederagenin is practically insoluble (in water) and a weakly acidic compound (based on its pKa). Hederagenin can be found in a number of food items such as rye, dill, european cranberry, and black salsify, which makes hederagenin a potential biomarker for the consumption of these food products. Hederagenin is the aglycone part of numerous saponins found in Hedera helix (common ivy). The most prevalent of these being hederacoside C and alpha-hederin. It is also one of three primary triterpenoids extracted from the Chenopodium quinoa plant categorized by the EPA as a biopesticide. HeadsUp Plant Protectant is made up of approximately equal ratios of the saponin aglycones oleanolic acid, hederagenin, and phytolaccagenic acid and is intended for use as a seed treatment on tuber (e.g. potato seed pieces), legume, and cereal seeds or as a pre-plant root dip for roots of transplants, at planting, to prevent fungal growth, bacterial growth, and viral plant diseases .
nortestosterone laurate
Pseudojujubogenin
Saikogenin A
triterpenoids
2alpha,3alpha-Dihydroxyolean-12-en-28-oic acid
2alpha,3alpha-dihydroxyolean-12-en-28-oic acid, also known as 2alpha,3alpha-dihydroxyolean-12-en-28-oate, is a member of the class of compounds known as triterpenoids. Triterpenoids are terpene molecules containing six isoprene units. 2alpha,3alpha-dihydroxyolean-12-en-28-oic acid is practically insoluble (in water) and a weakly acidic compound (based on its pKa). 2alpha,3alpha-dihydroxyolean-12-en-28-oic acid can be found in common sage, which makes 2alpha,3alpha-dihydroxyolean-12-en-28-oic acid a potential biomarker for the consumption of this food product. 2alpha,3alpha-dihydroxyolean-12-en-28-oic acid, also known as 2α,3α-dihydroxyolean-12-en-28-oate, is a member of the class of compounds known as triterpenoids. Triterpenoids are terpene molecules containing six isoprene units. 2alpha,3alpha-dihydroxyolean-12-en-28-oic acid is practically insoluble (in water) and a weakly acidic compound (based on its pKa). 2alpha,3alpha-dihydroxyolean-12-en-28-oic acid can be found in common sage, which makes 2alpha,3alpha-dihydroxyolean-12-en-28-oic acid a potential biomarker for the consumption of this food product.
Ursolic acid (2-alpha-hydroxy-)
Corosolic_acid
Corosolic acid is a triterpenoid. It has a role as a metabolite. Corosolic acid is a natural product found in Ternstroemia gymnanthera, Cunila lythrifolia, and other organisms with data available. See also: Lagerstroemia speciosa leaf (part of). A natural product found particularly in Rhododendron species and Eriobotrya japonica. Corosolic acid (Colosolic acid) isolated from the fruit of Cratoegus pinnatifida var. psilosa, was reported to have anticancer activity. Corosolic acid (Colosolic acid) isolated from the fruit of Cratoegus pinnatifida var. psilosa, was reported to have anticancer activity.
saikogenin A
Saikogenin A is a natural product found in Bupleurum falcatum with data available. Saikogenin D is a natural product found in Bupleurum and Bupleurum falcatum with data available. Saikogenin D is isolated from?Bupleurum chinense, has anti-inflammatory effects. Saikogenin D activates epoxygenases that converts arachidonic acid to epoxyeicosanoids and dihydroxyeicosatrienoic acids, and the metabolites secondarily inhibit prostaglandin E2 (PGE2) production. Saikogenin D results in an elevation of [Ca2+]i due to Ca2+ release from intracellular stores[1][2].
Anemosapogenin
23-Hydroxybetulinic acid is a triterpenoid. It has a role as a metabolite. It derives from a hydride of a lupane. 23-Hydroxybetulinic acid is a natural product found in Salvia, Syzygium sandwicense, and other organisms with data available. A natural product found in Paeonia rockii subspeciesrockii. 23-hydroxybetulinic acid is one of the bioactive components responsible for its anticancer activity. In vitro: 23-hydroxybetulinic acid also shows different proliferation inhibitory activity against B16, HeLa, and HUVEC, with the IC50 value of 78.5, 80, and 94.8 uM, respectively. 23-hydroxybetulinic acid can promote cell cycle arrest at S phase and induce apoptosis via intrinsic pathway. 23-hydroxybetulinic acid disrupts mitochondrial membrane potential significantly (p<0.01) and selectively downregulates the levels of Bcl-2, survivin and upregulates Bax, cytochrome C, cleaved caspase-9 23-hydroxybetulinic acid can induce apoptosis in K562 cells. [1] 23-hydroxybetulinic acid enhances sensitivity of doxorubicin (DOX, ADR) on MCF-7/ADR cell lines, indicating its potential to be developed as a novel MDR modulator.[2] 23-HBA significantly improve the sensitivity of the tumor to doxorubicin. [3] 23-hydroxybetulinic acid is one of the bioactive components responsible for its anticancer activity. In vitro: 23-hydroxybetulinic acid also shows different proliferation inhibitory activity against B16, HeLa, and HUVEC, with the IC50 value of 78.5, 80, and 94.8 uM, respectively. 23-hydroxybetulinic acid can promote cell cycle arrest at S phase and induce apoptosis via intrinsic pathway. 23-hydroxybetulinic acid disrupts mitochondrial membrane potential significantly (p<0.01) and selectively downregulates the levels of Bcl-2, survivin and upregulates Bax, cytochrome C, cleaved caspase-9 23-hydroxybetulinic acid can induce apoptosis in K562 cells. [1] 23-hydroxybetulinic acid enhances sensitivity of doxorubicin (DOX, ADR) on MCF-7/ADR cell lines, indicating its potential to be developed as a novel MDR modulator.[2] 23-HBA significantly improve the sensitivity of the tumor to doxorubicin. [3]
Hederagenin
Hederagenin is a sapogenin that is olean-12-en-28-oic acid substituted by hydroxy groups at positions 3 and 23 (the 3beta stereoisomer). It has a role as a plant metabolite. It is a pentacyclic triterpenoid, a dihydroxy monocarboxylic acid and a sapogenin. It is functionally related to an oleanolic acid. It is a conjugate acid of a hederagenin(1-). It derives from a hydride of an oleanane. Hederagenin is a natural product found in Zygophyllum obliquum, Sapindus emarginatus, and other organisms with data available. See also: Paeonia lactiflora root (part of); Caulophyllum robustum Root (part of); Medicago sativa whole (part of). A sapogenin that is olean-12-en-28-oic acid substituted by hydroxy groups at positions 3 and 23 (the 3beta stereoisomer). Hederagenin is a triterpenoid saponin that can inhibit the expression of iNOS, COX-2, and NF-κB in cells caused by LPS stimulation. Hederagenin is a triterpenoid saponin that can inhibit the expression of iNOS, COX-2, and NF-κB in cells caused by LPS stimulation.
Corosolic acid
Annotation level-1 Corosolic acid (Colosolic acid) isolated from the fruit of Cratoegus pinnatifida var. psilosa, was reported to have anticancer activity. Corosolic acid (Colosolic acid) isolated from the fruit of Cratoegus pinnatifida var. psilosa, was reported to have anticancer activity.
Rubiarbonone B
A pentacyclic triterpenoid of the class of arborinane-type terpenoids isolated from the roots of Rubia yunnanensis.
(5R,8S,9S,10S,11S,14R)-17-[(2R,4S,5S)-4,5-dihydroxy-6-methylhept-6-en-2-yl]-11-hydroxy-4,4,8,10,14-pentamethyl-1,2,5,6,7,9,11,12,15,16-decahydrocyclopenta[a]phenanthren-3-one
Wilforic acid C
A pentacyclic triterpenoid with formula C30H48O4, originally isolated from Tripterygium doianum.
Kuguacin R
Salaspermic acid
A hexacyclic triterpenoid that is D:A-friedooleanan-29-oic acid substituted by a hydroxy group at position 3 and an epoxy group across positions 3 and 24 (the (3beta,20alpha stereoisomer). Isolated from Salacia macrosperma and Tripterygium wilfordii, it exhibits anti-HIV activity.
13-(2-hydroxy-2,5,5,8a-tetramethyl-6-oxo-1,3,4,4a,7,8-hexahydronaphthalen-1-yl)-2,6,10-trimethyltrideca-2,6,10-trienoic acid
3alpha-Hydroxy-2-oxofriedelane-20alpha-carboxylic acid
Maslinic Acid
A pentacyclic triterpenoid that is 3alpha-hydroxy epimer of maslinic acid. Isolated from Prunella vulgaris and Isodon japonicus, it exhibits anti-inflammatory activity. Annotation level-1 Maslinic acid can inhibit the DNA-binding activity of NF-κB p65 and abolish the phosphorylation of IκB-α, which is required for p65 activation. Maslinic acid can inhibit the DNA-binding activity of NF-κB p65 and abolish the phosphorylation of IκB-α, which is required for p65 activation.
Triptocallic acid C
A hexacyclic triterpenoid with formula C30H48O4, originally isolated from Tripterygium wilfordii and Tripterygium hypoglaucum.
Triptocallic acid D
A pentacyclic triterpenoid with formula C30H48O4, originally isolated from Tripterygium wilfordii and Tripterygium hypoglaucum.
Triptotriterpenic acid B
A pentacyclic triterpenoid with formula C30H48O4, originally isolated from Tripterygium hypoglaucum.
23-Hydroxyursolic acid
A pentacyclic triterpenoid that is ursolic acid substituted by an additional hydroxy group at position 23. It has been isolated from Lagerstroemia speciosa and Juglans sinensis.
Mesembryanthemoidigenic acid
A pentacyclic triterpenoid with formula C30H48O4, originally isolated from Akebia quinata and Stauntonia hexaphylla.
27-Hydroxyisomangiferolic acid
Hecogenin acetate
Hecogenin acetate is a steroidal sapogenin-acetylated with anti-inflammatory and antinociceptive. Hecogenin acetate shows potential antihyperalgesic activity, inhibiting descending pain and acting in opioid receptors[1][2]. Hecogenin acetate is a steroidal sapogenin-acetylated with anti-inflammatory and antinociceptive. Hecogenin acetate shows potential antihyperalgesic activity, inhibiting descending pain and acting in opioid receptors[1][2].
3beta,6beta-dihydroxyurs-12-en-27-oic acid|3beta-hydroxyurs-12-en-27-oic acid|astilbotriterpenic acid
(-)-(23E)-25-hydroperoxytirucalla-8,23-dien-3beta-ol-7-one
(-)-(24S)-24-hydroperoxytirucalla-8,25-dien-3beta-ol-7-one
3alpha-(5-methyldodeca-2E,4E,6E-trienoyloxy)-9alpha,13-dihydroxy-10alphaH-eremophil-8-one-8-O-methylacetal|3alpha-<5-methyldodeca-2E,4E,6E-trienoyloxy>-9alpha,13-dihydroxy-10alphaH-eremophil-8-one-8-O-methylacetal
(22R,23S)-17alpha,23-epoxy-22,29-dihydroxy-27-norlanost-8-en-3,24-dione
3alpha-acetoxy-12alpha-hydroxy-20,24-dimethyl-25-norscalar-17-ene-18,24-carbolactone|phyllolactone C
25-hydroxy-23-oxo-3,4-seco-9betaH-lanost-4(28),7-dien-3-oic acid|seco-coccinic acid C
(24R)-7??,24,25-Trihydroxy-9,19-cycloart-1-en-3-one
(1alpha,3beta,11alpha)-1,3,11-Trihydroxygorgost-5-en-18-al
(20R*,23E)-25-hydroperoxyeupha-7,23-dien-16beta-ol-3-one|meliasenin J
2alpha,3beta,23-trihydroxy-30-noroleana-12,20-dien-28-oic acid|2??,3??,23-Trihydroxy-30-noroleana-12,20(21)-dien-28-oic acid
3beta,16alpha,28-Trihydroxy-olean-12-en-21-on|3beta,16alpha,28-trihydroxy-olean-12-en-21-one|Armillarigenin, 3beta.16alpha.28-Trihydroxy-21-oxo-Delta12-oleanen
3beta,6beta-dihydrolean-12-en-27-oic acid|3beta,6beta-dihydroxy-olean-12-en-27-oic acid|3beta,6beta-dihydroxyolean-12-en-27-oic acid|Astilbic acid
17,24-Dihydroxy-28,22-hopanolide|17,24-dihydroxyhopan-28,22-olide
(2alpha,19alpha)-2,19-dihydroxy-3-oxo-24-norolean-12-en-28-oic acid
4-(2-eicosyloxycarbonyl-vinyl)-benzoic acid and 4-(2-docosyloxycarbonyl-vinyl)-benzoic acid
(20S,24S)-20-acetoxy-12beta-hydroxy-20,23-dimethyl-25-norscarlar-17-ene-18,24-carbolactone|20-Ac-12,20-Dihydroxy-20,24-dimethyl-17-scalaren-25,24-olide
2-oxo-3beta,19alpha-dihydroxy-24-nor-urs-12-en-28-oic acid
1alpha,3beta-dihydroxyimberbic acid|1alpha,3beta-dihydroxyolean-12-en-29-oic acid|imberbic acid
(3beta,7beta)-ergost-5,24(28)-diene-3beta,7beta,19-triol 7-acetate|24-methyl-7beta-acetoxycholesta-5,24(28)-diene-3beta,19-diol|24-Methyl-7??-acetoxycholesta-5,24(28)-diene-3??,19-diol|7beta-acetoxy-24-methylcholesta-5-24(28)-diene-3,19-diol
3alpha,29-Dihydroxyolean-12-en-27-oic acid|3alpha-3,29-Dihydroxy-12-oleanen-27-oic acid
Saikogenin F
Saikogenin F is a natural product found in Bupleurum falcatum with data available. Saikogenin F exhibits anti-cancer activity[1]. Saikogenin F exhibits anti-cancer activity[1].
2alpha-hydroxy-3-oxo-D:A-friedooleanan-28-ioic acid|2alpha-hydroxy-3-oxo-D:A-friedooleanan-28-oic acid
2beta-hydroxy-4,7-diketo-A-norcholest-5-en-2-oic acid ethyl ester
Triptotriterpenic acid A
(6S,25)-dihydroxy-29-nor-3,4-seco-cycloart-4(30),23-dien-3-oic acid methyl ester
2alpha,3alpha,16alpha-trihydroxy-24-nor-olean-4(23),12-dien-28-oic acid
(1S,4S,5aS,5bR,7aS,11aS,11bR,13aS,13bR)-1,4,5,5a,5b,6,7,7a,8,9,10,11,11a,11b,12,13,13a,13b-octadecahydro-5b,8,8,11a,13a-pentamethylchryseno[1,2-c]furan-1,4-diol diacetate|hyrtiosin E
(3beta,6beta)-3,6-Dihydroxy-18-oleanen-28-oic acid
29,30-dinor-3beta-acetoxy-18,19-dioxo-18,19-secolupane
2,3-secoolean-12-en-3-oic-2,11-olide|dysoxyhainic acid D
(2alpha,3beta,20S)-20,24-epoxydammar-12,24-dien-2,3,29-triol|santolin B
3beta-hydroxy-20-oxo-30-nor-lupanoic acid-(28)-methyl ester|3beta-Hydroxy-20-oxo-30-nor-lupansaeure-(28)-methylester|methyl 3beta-hydroxy-20-oxo-30-norlupan-28-oate|methyl platanate|platanic acid methyl ester|Plataninsaeure-methylester|Platansaeure-methylester, 3beta-Hydroxy-20-oxo-30-norlupansaeure-(28)-methylester
20R-3beta-hydroxy-29-oxolupan-28-oic acid|Messagenic acid C
Alisol B|Alisol B, 24.25-Didesoxy-24-oxo-23xi-alisol A
(20R,24S)-3beta,25-dihydroxylanost-8-en-20,24-olide|inonotsulide A
(24R)-11-acetoxy-3beta-hydroxy-24-methyl-9,11-secocholest-5,22E-dien-9-one|leptosterol B
17S-(2-(1,2-dihydroxy-2-methylpropyl)-(20S,21S,23R)-4-hydroxycyclobutyl)-4,4,10,13,14-pentamethyl-4,5R,6,9R,10R,11,12,13S,14S,15,16,17S-dodecahydro-1H-cyclopenta[a]phenanthren-3(2H)-one|capulin
3beta,11alpha-dihydroxy-17,22-seco-17(28),12-ursadien-22-oic acid
(3beta,7alpha)-3,20-dihydroxyergosta-5,24(28)-dien-7-yl acetate|(3S,7S,8S,9S,10R,13S,14S,17S)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3-hydroxy-17-[(2S)-2-hydroxy-6-methyl-5-methylideneheptan-2-yl]-10,13-dimethyl-1H-cyclopenta[a]phenanthren-7-yl acetate
2alpha,3beta-dihydroxy-taraxer-20-en-28-oic acid|psiguanin A
(24E)-3β-hydroxy-9α-hydroxy-17,14-friedolanosta-14,24-dien-26-oic acid|garcihombronane K
3alpha-acetoxy-21beta-methoxy-24,25,26,27-tetranortirucall-7-ene-23(21)-lactone
1-[(1R,2S,3S,4S)-3-(hydroxymethyl)-2-(3-hydroxypropyl)-4-methyl-3-{(3E,5E)-4-methyl-6-[ (1R,5S)-2,5,6,6-tetramethylcyclohex-2-en-1-yl]hexa-3,5-dien-1-yl}-7-oxabicyclo[2.2.1]hept-1-yl]ethanone|irigermanone
3beta,15alpha,26,27-tetrahydroxy-5alpha-lanosta-7,9(11),24-trien|ganodermatetraol
(24E,3beta,22alpha)-3,22-dihydroxylanosta-8,24-dien-26-oic acid|astraodoric acid C
3beta,16beta,26,29-tetrahydroxy-5alpha-stigmasta-7,9(11),24(28)(Z)-trien-6-one
3,4-seco-29-nortirucalla-4,23-dione-7-ene-3-oic acid 3-methyl ester|aphanamgrandin H
3beta,7beta,25-trihydroxycucurbita-5,(23E)-dien-19-al
(2E,6E,10E)-14,15-dihydroxy-1-(2,5-dimethoxy-3-methylphenyl)-3,7,11,15-tetramethylhexadeca-2,6,10-trien-5-one|cystoazorol A
6beta-hydroxybetulinic acid|6??-Hydroxybetulinic acid
(20S,23S)-3beta,20-dihydroxyldammarane-24-ene-21-oic acid-21, 23-lactone
(5alpha,6beta,15beta,22E)-6-ethoxy-5,15-dihydroxyergosta-7,22-dien-3-one
(17R,20R)-27,29-dihydroxycycloart-24-en-3-olide|(1R,3aS,3bS,5aR,10aR,11aS,13aR)-tetradecahydro-6-(hydroxymethyl)-1-[(2R,5Z)-7-hydroxy-6-methylhept-5-en-2-yl]-3a,6,13a-trimethyl-8H-cyclopenta[5,6]cyclopropa[1,8a]naphtho[2,1-c]oxepin-8-one|gummiferartane-8
3alpha-hydroxy-2-oxo-D:A-friedooleanan-28-ioic acid|3alpha-hydroxy-2-oxo-D:A-friedooleanan-28-oic acid
5alpha-lanosta-7,9(11)-diene-3beta,25-diol-28-carboxylic acid|sexangulic acid
11-Ac-3beta-3,11-Dihydroxy-9,11-secoergosta-5,24(28)-dien-9-one|3beta-hydroxy-11-acetoxy-24-methylene-9,11-secocholest-5-en-9-one
6beta,12-dihydroxy-11alpha-methoxy-24-norurs-12-en-3-one
12alpha-acetoxy-20,24-dimethyl-24-oxoscalar-16-en-25beta-oic acid
(3beta,22beta)-3,22,24-Trihydroxy-12-oleanen-19-one|3beta,22beta,24-Trihydroxyolean-12-en-19-on|Sapogenin III
3beta,28alpha-dihydroxy-16-oxo-13beta,28-oxydooleanane
24-methylenecholestan-3-one-5alpha,6beta-diol-6-acetate
(25R)-3beta-Acetoxy-5alpha-spirostan-6-on|(25R)-3beta-acetoxy-5alpha-spirostan-6-one
2alpha,3alpha,19alpha-trihydroxy-24-norurs-4(23),12-dien-28-oic acid|2??,3??,19??-Trihydroxy-24-norurs-4(23),12-dien-28-oic acid
3beta,21beta,22beta-trihydroxyurs-12-en-28-al|cordianal C
(23R,24E)-3beta,23-dihydroxy-9beta-lanosta-7,24-dien-26-oic acid|abiesatrine F
3beta,21beta,24-trihydroxy-30-noroleana-12,20(29)-dien-28-oic acid
2alpha,3beta,23-trihydroxy-30-noroleana-12,20(29)-dien-28-oic acid|2??,3??,23-Trihydroxy-30-noroleana-12,20(29)-dien-28-oic acid|Norarjunolic acid|Norarjunolinsaeure
2-ethoxycarbonyl-2beta,6beta-dihydroxy-A-nor-cholesta-5,22(E)-dien-4-one
Ala Val Lys Arg
Hecogenin acetate
HECOGENIN ACETATE is a triterpenoid. Hecogenin acetate is a steroidal sapogenin-acetylated with anti-inflammatory and antinociceptive. Hecogenin acetate shows potential antihyperalgesic activity, inhibiting descending pain and acting in opioid receptors[1][2]. Hecogenin acetate is a steroidal sapogenin-acetylated with anti-inflammatory and antinociceptive. Hecogenin acetate shows potential antihyperalgesic activity, inhibiting descending pain and acting in opioid receptors[1][2].
Siraitic Acid A
3-Hydroxyspirostan-12-one (3beta,5alpha,25R)-form, Ac
Origin: Plant; SubCategory_DNP: The sterols, Cholestanes
Ala Lys Arg Val
Ala Lys Val Arg
Ala Arg Lys Val
Ala Arg Val Lys
Ala Val Arg Lys
Gly Ile Lys Arg
Gly Ile Arg Lys
Gly Lys Ile Arg
Gly Lys Leu Arg
Gly Lys Arg Ile
Gly Lys Arg Leu
Gly Leu Lys Arg
Gly Leu Arg Lys
Gly Arg Ile Lys
Gly Arg Lys Ile
Gly Arg Lys Leu
Gly Arg Leu Lys
Ile Gly Lys Arg
Ile Gly Arg Lys
Ile Lys Gly Arg
Ile Lys Arg Gly
Ile Arg Gly Lys
Ile Arg Lys Gly
Lys Ala Arg Val
Lys Ala Val Arg
Lys Gly Ile Arg
Lys Gly Leu Arg
Lys Gly Arg Ile
Lys Gly Arg Leu
Lys Ile Gly Arg
Lys Ile Arg Gly
Lys Lys Val Val
Lys Leu Gly Arg
Lys Leu Arg Gly
Lys Arg Ala Val
Lys Arg Gly Ile
Lys Arg Gly Leu
Lys Arg Ile Gly
Lys Arg Leu Gly
Lys Arg Val Ala
Lys Val Ala Arg
Lys Val Lys Val
Lys Val Arg Ala
Lys Val Val Lys
Leu Gly Lys Arg
Leu Gly Arg Lys
Leu Lys Gly Arg
Leu Lys Arg Gly
Leu Arg Gly Lys
Leu Arg Lys Gly
Arg Ala Lys Val
Arg Ala Val Lys
Arg Gly Ile Lys
Arg Gly Lys Ile
Arg Gly Lys Leu
Arg Gly Leu Lys
Arg Ile Gly Lys
Arg Ile Lys Gly
Arg Lys Ala Val
Arg Lys Gly Ile
Arg Lys Gly Leu
Arg Lys Ile Gly
Arg Lys Leu Gly
Arg Lys Val Ala
Arg Leu Gly Lys
Arg Leu Lys Gly
Arg Val Ala Lys
Arg Val Lys Ala
Val Ala Lys Arg
Val Ala Arg Lys
Val Lys Ala Arg
Val Lys Lys Val
Val Lys Arg Ala
Val Lys Val Lys
Val Arg Ala Lys
Val Arg Lys Ala
Val Val Lys Lys
Methyl 6'-apo-9'Z-lycopen-6'-oate
(3beta,17alpha,23R)-17,23-Epoxy-3,29-dihydroxy-27-norlanost-8-ene-15,24-dione
17a,23S-Epoxy-28,29-dihydroxy-27-norlanost-8-ene-3,24-dione
(23S,24S)-17,23-Epoxy-24,29-dihydroxy-27-norlanost-8-ene-3,15-dione
Reticulaxanthin
Spirostan-12-one, 3-(acetyloxy)-, (3beta,5alpha,25R)-
[3-carboxy-2-[(10E,15E)-9,12,13-trihydroxyoctadeca-10,15-dienoyl]oxypropyl]-trimethylazanium
20-[(2R,3R,5R,6S)-3,5-dihydroxy-6-methyloxan-2-yl]oxy-3-oxoicosanoic acid
(19R)-19-[(2R,3R,5R,6S)-3,5-dihydroxy-6-methyloxan-2-yl]oxy-3-oxoicosanoic acid
(1-butanoyloxy-3-hydroxypropan-2-yl) (4Z,7Z,10Z,13Z,16Z,19Z)-docosa-4,7,10,13,16,19-hexaenoate
[(1R,2S,4S,5S,6R,7S,8R,9S,12S,13S,16S,18S)-5,7,9,13-tetramethyl-10-oxospiro[5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icosane-6,2-oxane]-16-yl] acetate
(Z)-12,13-Bis[(trimethylsilyl)oxy]-9-octadecenoic acid methyl ester
(Z)-9,10-Bis[(trimethylsilyl)oxy]-12-octadecenoic acid methyl ester
[2-[(E)-dec-4-enoyl]oxy-3-hydroxypropyl] (5E,7E,9E,11E,13E)-hexadeca-5,7,9,11,13-pentaenoate
[2-[(4E,7E)-deca-4,7-dienoyl]oxy-3-hydroxypropyl] (7E,9E,11E,13E)-hexadeca-7,9,11,13-tetraenoate
[3-[3-acetyloxy-2-[(Z)-tridec-9-enoyl]oxypropoxy]-1-carboxypropyl]-trimethylazanium
(17alpha,23S)-Epoxy-28,29-dihydroxy-27-norlanost-8-ene-3,24-dione
3-{[(3r,3ar,5as,6r,7r,9as,9br)-3-(dimethoxymethyl)-3,3a,6,7,9a-pentamethyl-octahydro-1h-cyclopenta[a]naphthalen-6-yl]methyl}-4-hydroxybenzoic acid
(4e)-6-(2,5-dimethoxy-3-methylphenyl)-1-[(1s,2s)-2-(4-hydroxy-4-methylpentanoyl)-1,2-dimethylcyclopentyl]-4-methylhex-4-en-2-one
(3e,7e,11e)-13-(2,5-dimethoxy-3-methylphenyl)-1-(3,3-dimethyloxiran-2-yl)-3,7,11-trimethyltrideca-3,7,11-triene-2,9-diol
(1r,4s,5r,8r,9s,11r,13s,14s,17r,18s,21s,24r)-9,21-dihydroxy-5,8,11,14,17,24-hexamethyl-22-oxahexacyclo[19.2.1.0¹,¹⁸.0⁴,¹⁷.0⁵,¹⁴.0⁸,¹³]tetracosane-10,23-dione
3-(3,4-dimethoxyphenyl)prop-2-en-1-yl 18-hydroxyoctadeca-9,12-dienoate
6-(2,5-dimethoxy-3-methylphenyl)-1-[2-(4-hydroxy-4-methylpentanoyl)-1,2-dimethylcyclopentyl]-4-methylhex-4-en-2-one
2-acetyl-12-(acetyloxy)-7-ethyl-4b,7,10a,12a-tetramethyl-1,4,4a,5,6,6a,8,9,10,10b,11,12-dodecahydrochrysene-1-carboxylic acid
(1r,5s,8r,9r,12r,19r)-19-ethoxy-5,9,17,17-tetramethyl-8-[(2r)-4-oxopentan-2-yl]-18-oxapentacyclo[10.5.2.0¹,¹³.0⁴,¹².0⁵,⁹]nonadecane-3,16-dione
6,6-bis(hydroxymethyl)-3',3a,9a,11a-tetramethyl-5'-propanoyl-3,4,5,5a,8,9,10,11-octahydro-2h-spiro[cyclopenta[a]phenanthrene-1,2'-oxolan]-7-one
(3s,5br,8r,9r,11ar,13s,13as)-8-ethyl-13-hydroxy-3,5b,8,11a,13a-pentamethyl-1-oxo-3h,4h,5h,5ah,6h,7h,7ah,9h,10h,11h,11bh,12h,13h-chryseno[1,2-c]furan-9-yl acetate
1,10,11-trihydroxy-1,2,6a,6b,12a-pentamethyl-9-methylidene-2,3,4,5,6,7,8,8a,10,11,12,12b,13,14b-tetradecahydropicene-4a-carboxylic acid
5,10,11-trihydroxy-2,2,6a,6b,12a-pentamethyl-9-methylidene-1,3,4,5,6,7,8,8a,10,11,12,12b,13,14b-tetradecahydropicene-4a-carboxylic acid
9-hydroxy-9a-methoxy-4a,5-dimethyl-3-methylidene-octahydro-2h-naphtho[2,3-b]furan-6-yl 5-methyldodeca-2,4,6-trienoate
(3e,6r,10e,12r,14e)-16-(2,5-dimethoxy-3-methylphenyl)-2,12-dihydroxy-2,6,10,14-tetramethylhexadeca-3,10,14-trien-5-one
2α,3α,19α-trihydroxy-24-norurs-4(23),12-dien-28-oicacid
{"Ingredient_id": "HBIN005167","Ingredient_name": "2\u03b1,3\u03b1,19\u03b1-trihydroxy-24-norurs-4(23),12-dien-28-oicacid","Alias": "NA","Ingredient_formula": "C29H44O5","Ingredient_Smile": "CC1(CCC2(C(C1)C3=CCC4C(C3(CC2O)C)(CCC5C4(CC(C(C5=C)O)O)C)C)C(=O)O)C","Ingredient_weight": "NA","OB_score": "NA","CAS_id": "NA","SymMap_id": "NA","TCMID_id": "21801","TCMSP_id": "NA","TCM_ID_id": "NA","PubChem_id": "NA","DrugBank_id": "NA"}
2α,3β,23-trihydroxy-30-noroleana-12,20(21)-dien-28-oicacid
{"Ingredient_id": "HBIN005207","Ingredient_name": "2\u03b1,3\u03b2,23-trihydroxy-30-noroleana-12,20(21)-dien-28-oicacid","Alias": "NA","Ingredient_formula": "C29H44O5","Ingredient_Smile": "CC12CCC3C(C1CC=C4C2(CCC5(C4CC(=C)CC5)C(=O)O)C)(CC(C(C3(C)CO)O)O)C","Ingredient_weight": "NA","OB_score": "NA","CAS_id": "NA","SymMap_id": "NA","TCMID_id": "21796","TCMSP_id": "NA","TCM_ID_id": "NA","PubChem_id": "NA","DrugBank_id": "NA"}
2α,3β,23-trihydroxy-30-noroleana-12,20(29)-dien-28-oicacid
{"Ingredient_id": "HBIN005208","Ingredient_name": "2\u03b1,3\u03b2,23-trihydroxy-30-noroleana-12,20(29)-dien-28-oicacid","Alias": "NA","Ingredient_formula": "C29H44O5","Ingredient_Smile": "CC12CCC3C(C1CC=C4C2(CCC5(C4CC(=C)CC5)C(=O)O)C)(CC(C(C3(C)CO)O)O)C","Ingredient_weight": "NA","OB_score": "NA","CAS_id": "NA","SymMap_id": "NA","TCMID_id": "21797","TCMSP_id": "NA","TCM_ID_id": "NA","PubChem_id": "NA","DrugBank_id": "NA"}
