Saikogenin F (BioDeep_00000310650)
PANOMIX_OTCML-2023
代谢物信息卡片
化学式: C30H48O4 (472.3552408)
中文名称: 柴胡皂苷元 F
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC1(C)CCC23COC4(C=CC5C6(C)CCC(O)C(C)(CO)C6CCC5(C)C4(C)CC2O)C3C1
InChI: InChI=1S/C30H48O4/c1-24(2)13-14-29-18-34-30(21(29)15-24)12-8-20-25(3)10-9-22(32)26(4,17-31)19(25)7-11-27(20,5)28(30,6)16-23(29)33/h8,12,19-23,31-33H,7,9-11,13-18H2,1-6H3/t19-,20-,21-,22+,23+,25+,26+,27-,28+,29-,30+/m1/s1
描述信息
Saikogenin F is a natural product found in Bupleurum falcatum with data available.
Saikogenin F exhibits anti-cancer activity[1].
Saikogenin F exhibits anti-cancer activity[1].
同义名列表
数据库引用编号
6 个数据库交叉引用编号
- PubChem: 21594261
- PubChem: 12315174
- MeSH: saikogenin F
- CAS: 14356-59-3
- medchemexpress: HY-N7670
- PMhub: MS000081494
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
2 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Congcong Chen, Junshen Tian, Xiaoxia Gao, Xuemei Qin, Guanhua Du, Yuzhi Zhou. An integrated strategy to study the combination mechanisms of Bupleurum chinense DC and Paeonia lactiflora Pall for treating depression based on correlation analysis between serum chemical components profiles and endogenous metabolites profiles.
Journal of ethnopharmacology.
2023 Apr; 305(?):116068. doi:
10.1016/j.jep.2022.116068
. [PMID: 36574791] - Yue Li, Dongming Yan, Jingyi Jin, Bo Tan, Xi Chen, Bin Zou, Guochao Song, Fengyi Weng, Chenghai Liu, Furong Qiu. Clarify the potential cholestatic hepatotoxicity components from Chinese Herb Medicine and metabolism's role via hBSEP vesicles and S9/hBSEP vesicles.
Toxicology in vitro : an international journal published in association with BIBRA.
2022 Apr; 80(?):105324. doi:
10.1016/j.tiv.2022.105324
. [PMID: 35101544] - Dan-Qi Li, Le Zhou, Di Wang, Jie Wu, Ling-Zhi Li, Xiao-Xiao Huang, Qing-Bo Liu, Ying-Ying Wu, Song Lin, Jing-Yu Yang, Shao-Jiang Song, Chun-Fu Wu. Neuroprotective oleanane triterpenes from the roots of Bupleurum chinense.
Bioorganic & medicinal chemistry letters.
2016 Mar; 26(6):1594-1598. doi:
10.1016/j.bmcl.2016.02.004
. [PMID: 26883148] - Biao Zeng, Guang-Da Liu, Bao-Bao Zhang, Shan-shan Wang, Rui Ma, Bei-Shan Zhong, Bai-qiu He, Yan Liang, Fei-Hua Wu. A new triterpenoid saponin from Clinopodium chinense (Benth.) O. Kuntze.
Natural product research.
2016; 30(9):1001-8. doi:
10.1080/14786419.2015.1095745
. [PMID: 26511166] - Guoqiang Liu, Yuan Tian, Geng Li, Lei Xu, Rui Song, Zunjian Zhang. Metabolism of saikosaponin a in rats: diverse oxidations on the aglycone moiety in liver and intestine in addition to hydrolysis of glycosidic bonds.
Drug metabolism and disposition: the biological fate of chemicals.
2013 Mar; 41(3):622-33. doi:
10.1124/dmd.112.048975
. [PMID: 23277344] - Hyun-Ju Jung, Sei-Gun Kim, Jung-Hwan Nam, Kwang-Kyun Park, Won-Yun Chung, Won-Bae Kim, Kyung-Tae Lee, Jong-Heon Won, Jong-Won Choi, Hee-Juhn Park. Isolation of saponins with the inhibitory effect on nitric oxide, prostaglandin E2 and tumor necrosis factor-alpha production from Pleurospermum kamtschaticum.
Biological & pharmaceutical bulletin.
2005 Sep; 28(9):1668-71. doi:
10.1248/bpb.28.1668
. [PMID: 16141537] - Y Wang, S Xing, Y Yano, T Nomura. [Saponins in Bupleurum smithii Wolff var. parvifolium Shan et Y. Li].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
1998 Feb; 23(2):96-8, 128. doi:
"
. [PMID: 11596268]