Exact Mass: 456.3451
Exact Mass Matches: 456.3451
Found 500 metabolites which its exact mass value is equals to given mass value 456.3451,
within given mass tolerance error 0.05 dalton. Try search metabolite list with more accurate mass tolerance error
0.01 dalton.
Ursolic acid
Ursolic acid is a ubiquitous triterpenoid in plant kingdom, medicinal herbs, and is an integral part of the human diet. During the last decade over 700 research articles have been published on triterpenoids research, reflecting tremendous interest and progress in our understanding of these compounds. This included the isolation and purification of these tritepernoids from various plants and herbs, the chemical modifications to make more effective and water soluble derivatives, the pharmacological research on their beneficial effects, the toxicity studies, and the clinical use of these triterpenoids in various diseases including anticancer chemotherapies. Ursolic acid (UA), a pentacyclic triterpene acid, has been isolated from many kinds of medicinal plants, such as Eriobotrya japonica, Rosmarinns officinalis, Melaleuca leucadendron, Ocimum sanctum and Glechoma hederaceae. UA has been reported to produce antitumor activities and antioxidant activity, and is reported to have an antioxidant activity. UA may play an important role in regulating the apoptosis induced by high glucose presumably through scavenging of ROS (reactive oxygen species). It has been found recently that ursolic acid treatment affects growth and apoptosis in cancer cells. (PMID: 15994040, 17516235, 17213663). Ursolic acid is a pentacyclic triterpenoid that is urs-12-en-28-oic acid substituted by a beta-hydroxy group at position 3. It has a role as a plant metabolite and a geroprotector. It is a pentacyclic triterpenoid and a hydroxy monocarboxylic acid. It derives from a hydride of an ursane. Ursolic acid is a natural product found in Gladiolus italicus, Freziera, and other organisms with data available. Ursolic Acid is a pentacyclic triterpenoid found in various fruits, vegetables and medicinal herbs, with a variety of potential pharmacologic activities including anti-inflammatory, antioxidative, antiviral, serum lipid-lowering, and antineoplastic activities. Upon administration, ursolic acid may promote apoptosis and inhibit cancer cell proliferation through multiple mechanisms. This may include the regulation of mitochondrial function through various pathways including the ROCK/PTEN and p53 pathways, the suppression of the nuclear factor-kappa B (NF-kB) pathways, and the increase in caspase-3, caspase-8 and caspase-9 activities. See also: Holy basil leaf (part of); Jujube fruit (part of); Lagerstroemia speciosa leaf (part of). D018501 - Antirheumatic Agents > D000894 - Anti-Inflammatory Agents, Non-Steroidal > D016861 - Cyclooxygenase Inhibitors A pentacyclic triterpenoid that is urs-12-en-28-oic acid substituted by a beta-hydroxy group at position 3. C274 - Antineoplastic Agent > C129839 - Apoptotic Pathway-targeting Antineoplastic Agent Found in wax of apples, pears and other fruits. V. widely distributed in plants D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents D002491 - Central Nervous System Agents > D000700 - Analgesics C26170 - Protective Agent > C275 - Antioxidant D000893 - Anti-Inflammatory Agents D000890 - Anti-Infective Agents D000970 - Antineoplastic Agents D004791 - Enzyme Inhibitors 3-Epiursolic Acid is a triterpenoid that can be isolated from Eriobotrya japonica, acts as a competitive inhibitor of cathepsin L (IC50, 6.5 μM; Ki, 19.5 μM), with no obvious effect on cathepsin B[1]. 3-Epiursolic Acid is a triterpenoid that can be isolated from Eriobotrya japonica, acts as a competitive inhibitor of cathepsin L (IC50, 6.5 μM; Ki, 19.5 μM), with no obvious effect on cathepsin B[1]. Ursolic acid (Prunol) is a natural pentacyclic triterpenoid carboxylic acid, exerts anti-tumor effects and is an effective compound for cancer prevention and therapy. Ursolic acid (Prunol) is a natural pentacyclic triterpenoid carboxylic acid, exerts anti-tumor effects and is an effective compound for cancer prevention and therapy.
Betulinic acid
Betulinic acid is a pentacyclic triterpenoid that is lupane having a double bond at position 20(29) as well as 3beta-hydroxy and 28-carboxy substituents. It is found in the bark and other plant parts of several species of plants including Syzygium claviflorum. It exhibits anti-HIV, antimalarial, antineoplastic and anti-inflammatory properties. It has a role as an EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor, an anti-HIV agent, an antimalarial, an anti-inflammatory agent, an antineoplastic agent and a plant metabolite. It is a pentacyclic triterpenoid and a hydroxy monocarboxylic acid. It derives from a hydride of a lupane. Betulinic Acid has been used in trials studying the treatment of Dysplastic Nevus Syndrome. Betulinic acid is a natural product found in Ficus auriculata, Gladiolus italicus, and other organisms with data available. Betulinic Acid is a pentacyclic lupane-type triterpene derivative of betulin (isolated from the bark of Betula alba, the common white birch) with antiinflammatory, anti-HIV and antineoplastic activities. Betulinic acid induces apoptosis through induction of changes in mitochondrial membrane potential, production of reactive oxygen species, and opening of mitochondrial permeability transition pores, resulting in the release of mitochondrial apogenic factors, activation of caspases, and DNA fragmentation. Although originally thought to exhibit specific cytotoxicity against melanoma cells, this agent has been found to be cytotoxic against non-melanoma tumor cell types including neuroectodermal and brain tumor cells. A lupane-type triterpene derivative of betulin which was originally isolated from BETULA or birch tree. It has anti-inflammatory, anti-HIV and antineoplastic activities. See also: Jujube fruit (part of); Paeonia lactiflora root (part of). Betulinic acid is found in abiyuch. Betulinic acid is a naturally occurring pentacyclic triterpenoid which has anti-retroviral, anti-malarial, and anti-inflammatory properties, as well as a more recently discovered potential as an anticancer agent, by inhibition of topoisomerase. It is found in the bark of several species of plants, principally the white birch (Betula pubescens) from which it gets its name, but also the Ber tree (Ziziphus mauritiana), the tropical carnivorous plants Triphyophyllum peltatum and Ancistrocladus heyneanus, Diospyros leucomelas a member of the persimmon family, Tetracera boiviniana, the jambul (Syzygium formosanum), flowering quince (Chaenomeles sinensis), Rosemary, and Pulsatilla chinensis. Controversial is a role of p53 in betulinic acid-induced apoptosis. Fulda suggested p53-independent mechanism of the apoptosis, basing on fact of no accumulation of wild-type p53 detected upon treatment with the betulinic acid, whereas wild-type p53 protein strongly increased after treatment with doxorubicin. The suggestion is supported by study of Raisova. On the other hand Rieber suggested that betulinic acid exerts its inhibitory effect on human metastatic melanoma partly by increasing p53 A pentacyclic triterpenoid that is lupane having a double bond at position 20(29) as well as 3beta-hydroxy and 28-carboxy substituents. It is found in the bark and other plant parts of several species of plants including Syzygium claviflorum. It exhibits anti-HIV, antimalarial, antineoplastic and anti-inflammatory properties. C308 - Immunotherapeutic Agent > C2139 - Immunostimulant Betulinic acid is a natural pentacyclic triterpenoid, acts as a eukaryotic topoisomerase I inhibitor, with an IC50 of 5 μM, and possesses anti-HIV, anti-malarial, anti-inflammatory and anti-tumor properties[1][2][3][4]. Betulinic acid is a natural pentacyclic triterpenoid, acts as a eukaryotic topoisomerase I inhibitor, with an IC50 of 5 μM, and possesses anti-HIV, anti-malarial, anti-inflammatory and anti-tumor properties[1][2][3][4]. Epibetulinic acid exhibits potent inhibitory effects on NO and prostaglandin E2 (PGE2) production in mouse macrophages (RAW 264.7) stimulated with bacterial endotoxin with IC50s of 0.7 and 0.6 μM, respectively. Anti-inflammatory activity[1].
Oleanolic acid
Oleanolic acid is a pentacyclic triterpene, found in the non-glyceride fraction of olive pomace oil (Olive pomace oil, also known as "orujo" olive oil, is a blend of refined-pomace oil and virgin olive oil, fit for human consumption). Pentacyclic triterpenes are natural compounds which are widely distributed in plants. These natural products have been demonstrated to possess anti-inflammatory properties. Triterpenoids have been reported to possess antioxidant properties, since they prevent lipid peroxidation and suppress superoxide anion generation. The triterpenes have a history of medicinal use in many Asian countries. Oleanolic acid exhibits both pro- and anti-inflammatory properties depending on chemical structure and dose and may be useful in modulating the immune response; further studies are required to confirm the immunomodulatory behaviour of this triterpenoid, and characterise the mechanisms underlying the biphasic nature of some aspects of the inflammatory response. Oleanolic acid is a ubiquitous triterpenoid in plant kingdom, medicinal herbs, and is an integral part of the human diet. During the last decade over 700 research articles have been published on triterpenoids research, reflecting tremendous interest and progress in our understanding of these compounds. This included the isolation and purification of these tritepernoids from various plants and herbs, the chemical modifications to make more effective and water soluble derivatives, the pharmacological research on their beneficial effects, the toxicity studies, and the clinical use of these triterpenoids in various diseases including anticancer chemotherapies. (PMID:17292619, 15522132, 15994040). Oleanolic acid is a pentacyclic triterpenoid that is olean-12-en-28-oic acid substituted by a beta-hydroxy group at position 3. It has a role as a plant metabolite. It is a pentacyclic triterpenoid and a hydroxy monocarboxylic acid. It is a conjugate acid of an oleanolate. It derives from a hydride of an oleanane. Oleanolic acid is a natural product found in Ophiopogon japonicus, Freziera, and other organisms with data available. A pentacyclic triterpene that occurs widely in many PLANTS as the free acid or the aglycone for many SAPONINS. It is biosynthesized from lupane. It can rearrange to the isomer, ursolic acid, or be oxidized to taraxasterol and amyrin. See also: Holy basil leaf (part of); Jujube fruit (part of); Paeonia lactiflora root (part of) ... View More ... Occurs as glycosides in cloves (Syzygium aromaticum), sugar beet (Beta vulgaris), olive leaves, etc. Very widely distributed aglycone A pentacyclic triterpenoid that is olean-12-en-28-oic acid substituted by a beta-hydroxy group at position 3. [Raw Data] CBA90_Oleanolic-acid_neg_50eV.txt [Raw Data] CBA90_Oleanolic-acid_neg_20eV.txt [Raw Data] CBA90_Oleanolic-acid_neg_10eV.txt [Raw Data] CBA90_Oleanolic-acid_neg_30eV.txt [Raw Data] CBA90_Oleanolic-acid_neg_40eV.txt Oleanolic acid (Caryophyllin) is a natural compound from plants with anti-tumor activities. Oleanolic acid (Caryophyllin) is a natural compound from plants with anti-tumor activities.
alpha-Elemolic acid
alpha-Elemolic acid is found in herbs and spices. alpha-Elemolic acid is a constituent of elemi resin (from Canarium species). alpha-Elemolic acid is a flavouring agent Constituent of elemi resin (from Canarium subspecies). Flavouring agent. alpha-Elemolic acid is found in herbs and spices.
Soyasapogenol E
Constituent of soya bean (Glycine max). Soyasapogenol E is found in many foods, some of which are sapodilla, strawberry guava, purple mangosteen, and napa cabbage. Soyasapogenol E is found in pulses. Soyasapogenol E is a constituent of soya bean (Glycine max)
Glycyrrhetol
Saponin from licorice (Glycyrrhiza glabra). Glycyrrhetol is found in tea and herbs and spices. Glycyrrhetol is found in herbs and spices. Saponin from licorice (Glycyrrhiza glabra).
4alpha-Carboxy-stigmasta-7,24(24(1))-dien-3beta-ol
Boswellic acid
Boswellic acid (BA) is an active component of Boswellia serrata (also known as Salai guggul). Extensive research in the past 30 years identified the active component of this resin as BA (a pentacyclic triterpenic acid) and its derivatives (acetyl-beta-boswellic acid, 11-keto-beta-boswellic acid and acetyl-11-keto-beta-boswellic acid). In animal models of inflammation, BA has been shown to be an effective adjuvant mitigating bovine serum albumin-induced arthritis and osteoarthritis. The anti-arthritic potential of BA is a result of its anti-inflammatory activity, mediated through inhibition of NF-kB, COX-2 and 5-LOX. ((PMID: 17475558, 3429205). Boswellic acid is a triterpenoid. beta-Boswellic acid is a natural product found in Cyclocarya paliurus, Boswellia papyrifera, and other organisms with data available. D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents D002491 - Central Nervous System Agents > D000700 - Analgesics D000893 - Anti-Inflammatory Agents D018501 - Antirheumatic Agents β-Boswellic acid is isolated from the gum resin of Boswellia serrata. β-Boswellic acid is a nonreducing-type inhibitor of the 5-lipoxygenase (5-LO) product formation either interacting directly with the 5-LO or blocking its translocation[1]. β-Boswellic acid inhibits the synthesis of DNA, RNA and protein in human leukemia HL-60 cells[2]. β-Boswellic acid is isolated from the gum resin of Boswellia serrata. β-Boswellic acid is a nonreducing-type inhibitor of the 5-lipoxygenase (5-LO) product formation either interacting directly with the 5-LO or blocking its translocation[1]. β-Boswellic acid inhibits the synthesis of DNA, RNA and protein in human leukemia HL-60 cells[2]. β-Boswellic acid is isolated from the gum resin of Boswellia serrata. β-Boswellic acid is a nonreducing-type inhibitor of the 5-lipoxygenase (5-LO) product formation either interacting directly with the 5-LO or blocking its translocation[1]. β-Boswellic acid inhibits the synthesis of DNA, RNA and protein in human leukemia HL-60 cells[2].
3-Epioleanolic acid
3-epioleanolic acid is a triterpenoid. It has a role as a metabolite. 3-Epioleanolic acid is a natural product found in Conandron ramondioides, Gardenia ternifolia, and other organisms with data available. 3-Epioleanolic acid is found in common sage. 3-Epioleanolic acid is isolated from sage Salvia officinalis and other plants. Isolated from sage Salvia officinalis and other plants. 3-Epioleanolic acid is found in common sage. A natural product found in Radermachera boniana. 3-Epioleanolic acid is an active component of Verbena officinalis Linn, with anti-inflammatory activity[1]. 3-Epioleanolic acid is an active component of Verbena officinalis Linn, with anti-inflammatory activity[1].
3alpha-3-Hydroxytirucalla-7,24-dien-21-oic acid
3alpha-3-Hydroxytirucalla-7,24-dien-21-oic acid is found in herbs and spices. 3alpha-3-Hydroxytirucalla-7,24-dien-21-oic acid is a constituent of elemi resin (from Canarium species). 3alpha-3-Hydroxytirucalla-7,24-dien-21-oic acid is a flavouring agent 3alpha-3-Hydroxytirucalla-7,24-dien-21-oic acid is a triterpenoid.
beta-Elemolic acid
beta-Elemolic acid is found in herbs and spices. beta-Elemolic acid is a constituent of elemi resin. beta-Elemolic acid is a flavouring agent Constituent of elemi resin. Flavouring agent. beta-Elemolic acid is found in herbs and spices.
Isomangiferolic acid
Mangiferolic acid is found in fruits. Mangiferolic acid is a constituent of Mangifera indica (mango)
3-Epimasticadienolic acid
Masticadienolic acid is found in fruits. Masticadienolic acid is isolated from terebinth (Pistacia terebinthus). Isolated from terebinth (Pistacia terebinthus). 3-Epimasticadienolic acid is found in fruits.
3-Hydroxy-28,13-lupanolide
3-Hydroxy-28,13-lupanolide is found in beverages. 3-Hydroxy-28,13-lupanolide is a constituent of Dillenia indica (elephant apple). Constituent of Dillenia indica (elephant apple). 3-Hydroxy-28,13-lupanolide is found in beverages and fruits.
Ganodermatriol
Ganodermatriol is found in mushrooms. Ganodermatriol is a constituent of Ganoderma lucidum (reishi).
Ganoderic acid Z
Ganoderic acid Z is found in mushrooms. Ganoderic acid Z is isolated from Ganoderma lucidum (reishi). Isolated from Ganoderma lucidum (reishi). Ganoderic acid Z is found in mushrooms.
Oxyallobetulin
Oxyallobetulin is found in fruits. Oxyallobetulin is isolated from Diospyros lotus (date plum).
Katonic acid
Katonic acid is found in fruits. Katonic acid is a constituent of Sandoricum koetjape (santol) Constituent of Sandoricum koetjape (santol). Katonic acid is found in fruits.
3-Hydroxycycloart-24-en-21-oic acid
3-Hydroxycycloart-24-en-21-oic acid is found in fruits. 3-Hydroxycycloart-24-en-21-oic acid is a constituent of Lansium domesticum (langsat). Constituent of Lansium domesticum (langsat). 3-Hydroxycycloart-24-en-21-oic acid is found in fruits.
Lucidadiol
Lucidadiol is found in mushrooms. Lucidadiol is isolated from Ganoderma lucidum (reishi).
Epoxyganoderiol C
Epoxyganoderiol C is found in mushrooms. Epoxyganoderiol C is a metabolite of Ganoderma lucidum (reishi Metabolite of Ganoderma lucidum (reishi). Epoxyganoderiol C is found in mushrooms.
3beta-Hydroxy-28,13-ursanolide
3beta-Hydroxy-28,13-ursanolide is found in herbs and spices. 3beta-Hydroxy-28,13-ursanolide is isolated from Helichrysum italicum (curry plant). Isolated from Helichrysum italicum (curry plant). Ursolic acid lactone is found in tea and herbs and spices.
Bryonolic acid
Constituent of Sandoricum indicum (santol). Bryonolic acid is found in many foods, some of which are olive, calabash, towel gourd, and fruits. Bryonolic acid is found in calabash. Bryonolic acid is a constituent of Sandoricum indicum (santol).
Ganodermanondiol
Ganodermanondiol is found in mushrooms. Ganodermanondiol is a constituent of Ganoderma lucidum (reishi). Constituent of Ganoderma lucidum (reishi). Ganodermanondiol is found in mushrooms.
Citranaxanthin
Citranaxanthin is found in citrus. Citranaxanthin is a constituent of Sinton citrangequat (a Citrus-Poncirus-Fortunella hybrid) Citranaxanthin is a carotenoid pigment used as a food additive under the E number E161i as a food coloring. There are natural sources of citranaxanthin, but it is generally prepared synthetically. It is used as an animal feed additive to impart a yellow color to chicken fat and egg yolks. Constituent of Sinton citrangequat (a Citrus-Poncirus-Fortunella hybrid)
Sandosapogenol
Sapogenin from French bean (Phaseolus vulgaris) seed. Sandosapogenol is found in pulses, yellow wax bean, and green bean. Sandosapogenol is found in pulses. Sapogenin from French bean (Phaseolus vulgaris) see
(+-)-Ethyl 3-hydroxy-2-methylbutyrate
(+-)-Ethyl 3-hydroxy-2-methylbutyrate is used as a food additive [EAFUS] ("EAFUS: Everything Added to Food in the United States. [http://www.eafus.com/]") It is used as a food additive .
3-Epikatonic acid
3-Epikatonic acid is found in pulses. 3-Epikatonic acid is a constituent of Cyamopsis tetragonoloba (guar) Constituent of Cyamopsis tetragonoloba (guar). 3-Epikatonic acid is found in pulses.
Trametenolic acid B
Trametenolic acid B is found in mushrooms. Trametenolic acid B is a metabolite of Ganoderma tsugae (red reishi Metabolite of Ganoderma tsugae (red reishi). Trametenolic acid B is found in mushrooms. Trametenolic acid is a lanostanol glycoside that isolated from the EtOH extract of the fruit bodies of Laetiporus versisporus[1]. Trametenolic acid is a lanostanol glycoside that isolated from the EtOH extract of the fruit bodies of Laetiporus versisporus[1].
11-Deoxoglycyrrhetinic acid
11-Deoxoglycyrrhetinic acid is found in herbs and spices. 11-Deoxoglycyrrhetinic acid is isolated from roots of Glycyrrhiza glabra (licorice Isolated from roots of Glycyrrhiza glabra (licorice). 11-Deoxoglycyrrhetinic acid is found in tea and herbs and spices.
Carissic acid
Ustiloxin E is found in cereals and cereal products. Ustiloxin E is isolated from the false smut balls caused by Ustilaginoidea virens on rice. Constituent of Carissa carandas (karanda). Carissic acid is found in beverages and fruits.
N-Docosahexaenoyl Lysine
N-docosahexaenoyl lysine belongs to the class of compounds known as N-acylamides. These are molecules characterized by a fatty acyl group linked to a primary amine by an amide bond. More specifically, it is a Docosahexaenoyl amide of Lysine. It is believed that there are more than 800 types of N-acylamides in the human body. N-acylamides fall into several categories: amino acid conjugates (e.g., those acyl amides conjugated with amino acids), neurotransmitter conjugates (e.g., those acylamides conjugated with neurotransmitters), ethanolamine conjugates (e.g., those acylamides conjugated to ethanolamine), and taurine conjugates (e.g., those acyamides conjugated to taurine). N-Docosahexaenoyl Lysine is an amino acid conjugate. N-acylamides can be classified into 9 different categories depending on the size of their acyl-group: 1) short-chain N-acylamides; 2) medium-chain N-acylamides; 3) long-chain N-acylamides; and 4) very long-chain N-acylamides; 5) hydroxy N-acylamides; 6) branched chain N-acylamides; 7) unsaturated N-acylamides; 8) dicarboxylic N-acylamides and 9) miscellaneous N-acylamides. N-Docosahexaenoyl Lysine is therefore classified as a very long chain N-acylamide. N-acyl amides have a variety of signaling functions in physiology, including in cardiovascular activity, metabolic homeostasis, memory, cognition, pain, motor control and others (PMID: 15655504). N-acyl amides have also been shown to play a role in cell migration, inflammation and certain pathological conditions such as diabetes, cancer, neurodegenerative disease, and obesity (PMID: 23144998; PMID: 25136293; PMID: 28854168).N-acyl amides can be synthesized both endogenously and by gut microbiota (PMID: 28854168). N-acylamides can be biosynthesized via different routes, depending on the parent amine group. N-acyl ethanolamines (NAEs) are formed via the hydrolysis of an unusual phospholipid precursor, N-acyl-phosphatidylethanolamine (NAPE), by a specific phospholipase D. N-acyl amino acids are synthesized via a circulating peptidase M20 domain containing 1 (PM20D1), which can catalyze the bidirectional the condensation and hydrolysis of a variety of N-acyl amino acids. The degradation of N-acylamides is largely mediated by an enzyme called fatty acid amide hydrolase (FAAH), which catalyzes the hydrolysis of N-acylamides into fatty acids and the biogenic amines. Many N-acylamides are involved in lipid signaling system through interactions with transient receptor potential channels (TRP). TRP channel proteins interact with N-acyl amides such as N-arachidonoyl ethanolamide (Anandamide), N-arachidonoyl dopamine and others in an opportunistic fashion (PMID: 23178153). This signaling system has been shown to play a role in the physiological processes involved in inflammation (PMID: 25136293). Other N-acyl amides, including N-oleoyl-glutamine, have also been characterized as TRP channel antagonists (PMID: 29967167). N-acylamides have also been shown to have G-protein-coupled receptors (GPCRs) binding activity (PMID: 28854168). The study of N-acylamides is an active area of research and it is likely that many novel N-acylamides will be discovered in the coming years. It is also likely that many novel roles in health and disease will be uncovered for these molecules.
Epibetulinic acid
Betulinic acid is a naturally occurring pentacyclic triterpenoid which has anti-retroviral, anti-malarial, and anti-inflammatory properties, as well as a more recently discovered potential as an anticancer agent, by inhibition of topoisomerase. It is found in the bark of several species of plants, principally the white birch (Betula pubescens) from which it gets its name, but also the Ber tree (Ziziphus mauritiana), the tropical carnivorous plants Triphyophyllum peltatum and Ancistrocladus heyneanus, Diospyros leucomelas a member of the persimmon family, Tetracera boiviniana, the jambul (Syzygium formosanum), flowering quince (Chaenomeles sinensis), Rosemary, and Pulsatilla chinensis.; Controversial is a role of p53 in betulinic acid-induced apoptosis. Fulda suggested p53-independent mechanism of the apoptosis, basing on fact of no accumulation of wild-type p53 detected upon treatment with the betulinic acid, whereas wild-type p53 protein strongly increased after treatment with doxorubicin. The suggestion is supported by study of Raisova. On the other hand Rieber suggested that betulinic acid exerts its inhibitory effect on human metastatic melanoma partly by increasing p53. Betulinic acid is a natural pentacyclic triterpenoid, acts as a eukaryotic topoisomerase I inhibitor, with an IC50 of 5 μM, and possesses anti-HIV, anti-malarial, anti-inflammatory and anti-tumor properties[1][2][3][4]. Betulinic acid is a natural pentacyclic triterpenoid, acts as a eukaryotic topoisomerase I inhibitor, with an IC50 of 5 μM, and possesses anti-HIV, anti-malarial, anti-inflammatory and anti-tumor properties[1][2][3][4].
b-Boswellic acid
Constituent of frankincense (Boswellia subspecies) and olibanum oil β-Boswellic acid is isolated from the gum resin of Boswellia serrata. β-Boswellic acid is a nonreducing-type inhibitor of the 5-lipoxygenase (5-LO) product formation either interacting directly with the 5-LO or blocking its translocation[1]. β-Boswellic acid inhibits the synthesis of DNA, RNA and protein in human leukemia HL-60 cells[2]. β-Boswellic acid is isolated from the gum resin of Boswellia serrata. β-Boswellic acid is a nonreducing-type inhibitor of the 5-lipoxygenase (5-LO) product formation either interacting directly with the 5-LO or blocking its translocation[1]. β-Boswellic acid inhibits the synthesis of DNA, RNA and protein in human leukemia HL-60 cells[2]. β-Boswellic acid is isolated from the gum resin of Boswellia serrata. β-Boswellic acid is a nonreducing-type inhibitor of the 5-lipoxygenase (5-LO) product formation either interacting directly with the 5-LO or blocking its translocation[1]. β-Boswellic acid inhibits the synthesis of DNA, RNA and protein in human leukemia HL-60 cells[2].
Nandrolone laurate
Testosterone undecanoate
alpha-Boswellic acid
alpha-Boswellic acid is a natural product found in Cyclocarya paliurus, Boswellia sacra, and other organisms with data available. alpha-Boswellic acid (α-Boswellic acid) is a pentacyclic triterpene compound from extracts of Frankincense, has anticonvulsant and anti-cancer properties[1]. alpha-Boswellic acid prevents and decreases the progression of Alzheimer’s hallmarks in vivo and can be used for Alzheimer’s disease research[2]. alpha-Boswellic acid (α-Boswellic acid) is a pentacyclic triterpene compound from extracts of Frankincense, has anticonvulsant and anti-cancer properties[1]. alpha-Boswellic acid prevents and decreases the progression of Alzheimer’s hallmarks in vivo and can be used for Alzheimer’s disease research[2]. alpha-Boswellic acid. CAS Common Chemistry. CAS, a division of the American Chemical Society, n.d. https://commonchemistry.cas.org/detail?cas_rn=471-66-9 (retrieved 2024-08-21) (CAS RN: 471-66-9). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).
Gadermandiol
Ganodermanondiol is a triterpenoid. (5R,10S,13R,14R,17R)-17-[(2R,5S)-5,6-dihydroxy-6-methylheptan-2-yl]-4,4,10,13,14-pentamethyl-1,2,5,6,12,15,16,17-octahydrocyclopenta[a]phenanthren-3-one is a natural product found in Ganoderma lucidum with data available.
Merotaine
3-Epiursolic acid is a natural product found in Pavetta indica, Conandron ramondioides, and other organisms with data available. 3-Epiursolic Acid is a triterpenoid that can be isolated from Eriobotrya japonica, acts as a competitive inhibitor of cathepsin L (IC50, 6.5 μM; Ki, 19.5 μM), with no obvious effect on cathepsin B[1]. 3-Epiursolic Acid is a triterpenoid that can be isolated from Eriobotrya japonica, acts as a competitive inhibitor of cathepsin L (IC50, 6.5 μM; Ki, 19.5 μM), with no obvious effect on cathepsin B[1].
α-Boswellic acid
alpha-Boswellic acid is a natural product found in Cyclocarya paliurus, Boswellia sacra, and other organisms with data available. alpha-Boswellic acid (α-Boswellic acid) is a pentacyclic triterpene compound from extracts of Frankincense, has anticonvulsant and anti-cancer properties[1]. alpha-Boswellic acid prevents and decreases the progression of Alzheimer’s hallmarks in vivo and can be used for Alzheimer’s disease research[2]. alpha-Boswellic acid (α-Boswellic acid) is a pentacyclic triterpene compound from extracts of Frankincense, has anticonvulsant and anti-cancer properties[1]. alpha-Boswellic acid prevents and decreases the progression of Alzheimer’s hallmarks in vivo and can be used for Alzheimer’s disease research[2].
α-boswellic acid
alpha-Boswellic acid (α-Boswellic acid) is a pentacyclic triterpene compound from extracts of Frankincense, has anticonvulsant and anti-cancer properties[1]. alpha-Boswellic acid prevents and decreases the progression of Alzheimer’s hallmarks in vivo and can be used for Alzheimer’s disease research[2]. alpha-Boswellic acid (α-Boswellic acid) is a pentacyclic triterpene compound from extracts of Frankincense, has anticonvulsant and anti-cancer properties[1]. alpha-Boswellic acid prevents and decreases the progression of Alzheimer’s hallmarks in vivo and can be used for Alzheimer’s disease research[2].
Ursolic acid lactone
Ursolic Acid
Origin: Plant; SubCategory_DNP: Triterpenoids relative retention time with respect to 9-anthracene Carboxylic Acid is 1.636 relative retention time with respect to 9-anthracene Carboxylic Acid is 1.640 relative retention time with respect to 9-anthracene Carboxylic Acid is 1.638 relative retention time with respect to 9-anthracene Carboxylic Acid is 1.642 Ursolic acid (Prunol) is a natural pentacyclic triterpenoid carboxylic acid, exerts anti-tumor effects and is an effective compound for cancer prevention and therapy. Ursolic acid (Prunol) is a natural pentacyclic triterpenoid carboxylic acid, exerts anti-tumor effects and is an effective compound for cancer prevention and therapy.
CC12CCC(O)C(C)(C)C1CCC(C1(C)CC3=O)(C)C2CCC11OCC32CCC(C)(C)CC21
Secaubryenol
Lansiolic acid
A triterpenoid of the class of onoceranoid-type terpenoids isolated from the twigs of Lansium domesticum.
Ganodermanondiol
14beta,15beta-Epoxy-21beta-hydroxyserratan-3-one
Anwuweizic acid
Isomangiferolic acid
3-Hydroxycycloart-24-en-21-oic acid
(23Xi)-3alpha,23-dihydroxy-tirucalla-7,24-dien-21-al
20alpha-dimethylamino-16beta-hydroxy-3-senecioylamino-5alpha-pregn-2-en-4-one|pachysamine N
(12beta,23E)-12,20-dihydroxydammara-23,25-dien-3-one|cylindrictone A
4,4-Dimethyl-24-methylenecholesta-8,14-diene-3,11,12-triol
(24Z)-3a-oxa-3a-homo-27-hydroxy-7,24-tirucalladien-3-one
(22R)-22-hydroxy-24-methylene-3-norlanost-8-en-28-oic acid|gilvsin D
3alpha-hydroxy-bauer-7-en-28-oic acid|Myrtifolsaeure
D:A-Friedooleanane-1,3-dione, 7-hydroxy-, (7.alpha.)-
3beta-hydroxylup-20(29)-en-30-oic acid|betulinic acid
(4aR,6aR,6aR,6bR,8aR,10S,12aR,14bR)-10-hydroxy-2,2,4a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-6a-carboxylic acid
(22alpha,20?鈥?-form-20,29-Epoxy-22-hydroxy-3-lupanone
(3beta)-3-hydroxy-18(13->12beta)-abeo-lanosta-13(17),24-dien-18-oic acid|(3beta,5alpha,12beta)-17-[(1R)-1,5-dimethylhex-4-en-1-yl]-3-hydroxy-4,4,10,14-tetramethylgon-13(17)-ene-12-carboxylic acid|fornicatin C
D:A-friedo-3-oxo-oleanane-27-carboxylic acid|Trichadonic acid
20(R)-21,24-Cyclo-3??,25-dihydroxyldammar-23(24)-en-21-one
21beta-hydroxy-3,4-seco-lupa-4(23),20(29)-dien-3-oic acid|lippiolic acid
3-[(3S,3aR,5aR,6S,7S,9aR,9bR)-6,9a,9b-trimethyl-3-[(2S,5S)-2-methyl-5-prop-1-en-2-yloxolan-2-yl]-7-prop-1-en-2-yl-1,2,3,3a,4,5,5a,7,8,9-decahydrocyclopenta[a]naphthalen-6-yl]propanoic acid
28,30-dihydroxy-3-oxolup-20(29)-ene|28,30-dihydroxylup-20(29)-en-3-one|28,30-dihydroxylup-20(29)-ene-3-one
3beta-hydroxy-D:A-friedo-oleanan-27,16alpha-lactone
3beta,11alpha-dihydroxy-4alpha,14alpha-dimethyl-5alpha-ergosta-8,24(28)-dien-7-one
3beta,24-dihydroxyolean-12-en-21-one|Soyasapogenol-E
(22R)-3beta,22-dihydroxylanosta-8,24-dien-11-one|3beta,22-dihydroxylanosta-8,24-dien-11-one|inonotsuoxodiol A
3,4-seco-cycloart-4(29),25-dien-24-hydroxy-3-oic acid|coccinetane F
3-oxo-D:A-friedooleanan-28-oic acid|3-oxofriedelan-28-oic acid|7beta-hydroxy-3-oxofriedelan-28-oic acid|canophyllic acid|Friedelin-28-saeure|oxocanophyllic acid
26-hydroxy-1,3-friedelanedione|26-hydroxyfriedelane-1,3-dione
(14beta,21beta)-14,26-Epoxy-21-hydroxy-3-serratanone|21beta-hydroxy-14beta,26-epoxy-serratane-3-one
3beta,7alpha-dihydroxy-4alpha,14alpha-dimethyl-5alpha-ergosta-8,24(28)-dien-11-one
3-beta-28-Carboxylic acid-12-Lupen-3,28-diol|3beta-3-Hydroxy-12-lupen-28-oic acid
12,13-dihydromicromeric acid|18betaH-urs-20(30)-en-3beta-ol-28-oic acd
1alpha,3beta-dihydroxy-5alpha-cycloart-24-en-23-one|thailandiol
(23R,25R)-3alpha-Hydroxy-9,19-cyclo-9beta-lanostan-26,23-olide
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Citranaxanthin
D020011 - Protective Agents > D000975 - Antioxidants > D002338 - Carotenoids
ascr#35
An (omega-1)-hydroxy fatty acid ascaroside obtained by formal condensation of the alcoholic hydroxy group of (2E,19R)-19-hydroxyicos-2-enoic acid with ascarylopyranose (the alpha anomer). It is a metabolite of the nematode Caenorhabditis elegans.
oscr#35
An omega-hydroxy fatty acid ascaroside obtained by formal condensation of the alcoholic hydroxy group of (2E)-20-hydroxyicos-2-enoic acid with ascarylopyranose (the alpha anomer). It is a metabolite of the nematode Caenorhabditis elegans.
