Trametenolic acid B (BioDeep_00000034844)

Secondary id: BioDeep_00000619818

human metabolite PANOMIX_OTCML-2023 Endogenous

代谢物信息卡片

(2R)-2-[(2S,5S,7R,11R,14R,15R)-5-hydroxy-2,6,6,11,15-pentamethyltetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadec-1(10)-en-14-yl]-6-methylhept-5-enoic acid

化学式: C30H48O3 (456.36032579999994)
中文名称:
谱图信息: 最多检出来源 Chinese Herbal Medicine(otcml) 85.71%

分子结构信息

SMILES: C1[C@@H](C([C@H]2[C@](C1)(C1=C(CC2)[C@]2([C@](CC1)([C@H](CC2)[C@H](C(=O)O)CCC=C(C)C)C)C)C)(C)C)O
InChI: InChI=1S/C30H48O3/c1-19(2)9-8-10-20(26(32)33)21-13-17-30(7)23-11-12-24-27(3,4)25(31)15-16-28(24,5)22(23)14-18-29(21,30)6/h9,20-21,24-25,31H,8,10-18H2,1-7H3,(H,32,33)/t20-,21-,24+,25+,28-,29-,30+/m1/s1

描述信息

Trametenolic acid B is found in mushrooms. Trametenolic acid B is a metabolite of Ganoderma tsugae (red reishi
Metabolite of Ganoderma tsugae (red reishi). Trametenolic acid B is found in mushrooms.
Trametenolic acid is a lanostanol glycoside that isolated from the EtOH extract of the fruit bodies of Laetiporus versisporus[1].
Trametenolic acid is a lanostanol glycoside that isolated from the EtOH extract of the fruit bodies of Laetiporus versisporus[1].

同义名列表

8 个代谢物同义名

(2R)-2-[(2S,5S,7R,11R,14R,15R)-5-hydroxy-2,6,6,11,15-pentamethyltetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadec-1(10)-en-14-yl]-6-methylhept-5-enoic acid; (2R)-2-[(2S,5S,7R,11R,14R,15R)-5-Hydroxy-2,6,6,11,15-pentamethyltetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadec-1(10)-en-14-yl]-6-methylhept-5-enoate; 3-Hydroxy-(3beta)-lanosta-8,24-dien-21-Oic acid; 3beta-Hydroxylanosta-8,24-dien-21-oic acid; (+)-Trametenolic acid B; Trametenolic acid B; Trametenolic acid; Trametenolate b

数据库引用编号

9 个数据库交叉引用编号

ChEBI: CHEBI:173148
PubChem: 12309443
HMDB: HMDB0035511
ChEMBL: CHEMBL387689
KNApSAcK: C00023783
foodb: FDB014201
chemspider: 10193870
CAS: 24160-36-9
medchemexpress: HY-N4169

分类词条

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

11 个相关的物种来源信息

40483 - Fomitopsis pinicola:
1050263 - Fuscoporia senex: 10.1039/P19750000451
34467 - Ganoderma tsugae:
139427 - Gloeophyllum odoratum:
9606 - Homo sapiens: -
167356 - Inonotus obliquus:
5630 - Laetiporus sulphureus:
447507 - Laetiporus versisporus: 10.1021/NP980456I
1040649 - Pappia fissilis:
113602 - Tricholoma saponaceum: 10.1248/CPB.50.1603
81056 - Wolfiporia cocos:

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

文献列表

Junzhi Wang, Ailing Wang, Haibo He, Xinxin She, Yumin He, Shi Li, Lanqing Liu, Tao Luo, Nianyu Huang, Huajun Luo, Kun Zou. Trametenolic acid B protects against cerebral ischemia and reperfusion injury through modulation of microRNA-10a and PI3K/Akt/mTOR signaling pathways. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2019 Apr; 112(?):108692. doi: 10.1016/j.biopha.2019.108692. [PMID: 30798122]
Qiaoyin Zhang, Nianyu Huang, Junzhi Wang, Huajun Luo, Haibo He, Mingruo Ding, Wei-Qiao Deng, Kun Zou. The H+/K+-ATPase inhibitory activities of Trametenolic acid B from Trametes lactinea (Berk.) Pat, and its effects on gastric cancer cells. Fitoterapia. 2013 Sep; 89(?):210-7. doi: 10.1016/j.fitote.2013.05.021. [PMID: 23742858]
Tomoko Nakata, Takeshi Yamada, Sayaka Taji, Hirofumi Ohishi, Shun-Ichi Wada, Harukuni Tokuda, Kazuo Sakuma, Reiko Tanaka. Structure determination of inonotsuoxides A and B and in vivo anti-tumor promoting activity of inotodiol from the sclerotia of Inonotus obliquus. Bioorganic & medicinal chemistry. 2007 Jan; 15(1):257-64. doi: 10.1016/j.bmc.2006.09.064. [PMID: 17049251]