Exact Mass: 441.24748800000003
Exact Mass Matches: 441.24748800000003
Found 406 metabolites which its exact mass value is equals to given mass value 441.24748800000003
,
within given mass tolerance error 0.05 dalton. Try search metabolite list with more accurate mass tolerance error
0.01 dalton.
Lisinopril dihydrate
C21H31N3O5. 2H2O (441.24748800000003)
Therapeutic category: 2144 2179
Leukotriene E3
C23H39NO5S (441.25488040000005)
Leukotriene E3 is an eicosanoid derived from 8,11,14-Eicosatrienoic acid by the 5-Lipoxygenase-Leukotriene Pathway. The eicosanoids are a diverse family of molecules that have powerful effects on cell function. They are best known as intercellular messengers, having autocrine and paracrine effects following their secretion from the cells that synthesize them. The diversity of possible products that can be synthesized from eicosatrienoic acid is due, in part to the variety of enzymes that can act on it. Studies have placed many, but not all, of these enzymes at or inside the nucleus. In some cases, the nuclear import or export of eicosatrienoic acid-processing enzymes is highly regulated. Furthermore, nuclear receptors that are activated by specific eicosanoids are known to exist. Taken together, these findings indicate that the enzymatic conversion of eicosatrienoic acid to specific signaling molecules can occur in the nucleus, that it is regulated, and that the synthesized products may act within the nucleus. Leukotriene E3 is also a by-product of the metabolism of leukotriene C3. Although they are primarily known for their roles in asthma, pain, fever and vascular responses, present evidence indicates that eicosanoids exert relevant effects on immune/inflammatory, as well as structural, cells pertinent to fibrogenesis. (PMID: 7306127, 8142566, 16574479, 15896193)Leukotrienes are eicosanoids. The eicosanoids consist of the prostaglandins (PGs), thromboxanes (TXs), leukotrienes (LTs), and lipoxins (LXs). The PGs and TXs are collectively identified as prostanoids. Prostaglandins were originally shown to be synthesized in the prostate gland, thromboxanes from platelets (thrombocytes), and leukotrienes from leukocytes, hence the derivation of their names. All mammalian cells except erythrocytes synthesize eicosanoids. These molecules are extremely potent, able to cause profound physiological effects at very dilute concentrations. All eicosanoids function locally at the site of synthesis, through receptor-mediated G-protein linked signalling pathways. Leukotriene E3 is an eicosanoid derived from 8,11,14-Eicosatrienoic acid by the 5-Lipoxygenase-Leukotriene Pathway. The eicosanoids are a diverse family of molecules that have powerful effects on cell function. They are best known as intercellular messengers, having autocrine and paracrine effects following their secretion from the cells that synthesize them. The diversity of possible products that can be synthesized from eicosatrienoic acid is due, in part to the variety of enzymes that can act on it. Studies have placed many, but not all, of these enzymes at or inside the nucleus. In some cases, the nuclear import or export of eicosatrienoic acid-processing enzymes is highly regulated. Furthermore, nuclear receptors that are activated by specific eicosanoids are known to exist. Taken together, these findings indicate that the enzymatic conversion of eicosatrienoic acid to specific signaling molecules can occur in the nucleus, that it is regulated, and that the synthesized products may act within the nucleus. Leukotriene E3 is also a by-product of the metabolism of leukotriene C3. Although they are primarily known for their roles in asthma, pain, fever and vascular responses, present evidence indicates that eicosanoids exert relevant effects on immune/inflammatory, as well as structural, cells pertinent to fibrogenesis. (PMID: 7306127, 8142566, 16574479, 15896193)
Vilazodone
Vilazodone is a novel compound with combined high affinity and selectivity for the 5-hydroxytryptamine (5-HT) transporter and 5-HT(1A) receptors. It has been shown to be equally efficacious as other antidepressants with similar gastrointestinal side effects and possibly with reduced sexual side effects and weight gain. Vilazodone is an antidepressant agent that can used as an alternative for patients who cannot tolerate therapy with other antidepressant classes such as selective serotonin reuptake inhibitors or serotonin norepinephrine reuptake inhibitors. Treatment should be titrated towards the target dose, which is 40mg per day. D018377 - Neurotransmitter Agents > D018490 - Serotonin Agents > D017367 - Selective Serotonin Reuptake Inhibitors D002491 - Central Nervous System Agents > D011619 - Psychotropic Drugs > D000928 - Antidepressive Agents D018377 - Neurotransmitter Agents > D018490 - Serotonin Agents > D017366 - Serotonin Receptor Agonists D018377 - Neurotransmitter Agents > D014179 - Neurotransmitter Uptake Inhibitors C78272 - Agent Affecting Nervous System > C265 - Antidepressant Agent N - Nervous system > N06 - Psychoanaleptics > N06A - Antidepressants D049990 - Membrane Transport Modulators Vilazodone (EMD 68843; SB 659746A) is a potent, selective and orally active?serotonin?reuptake inhibitor (SSRI) and partial?5-HT1A receptor agonist. Vilazodone exhibits antidepressant efficacy in vivo can be used for the research of major depressive disorder (MDD) and affective disorders[1][2].
3-N-(2-Fluoroethyl)spiperone
C25H29F2N3O2 (441.22277180000003)
D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents > D019275 - Radiopharmaceuticals
Pentanoic acid, 5-(dipentylamino)-5-oxo-4-((3-quinolinylcarbonyl)amino)-, (R)-
C25H35N3O4 (441.26274300000006)
Cerivastatin lactone
Deflazacort
4-(2-((4-(2-(Pyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)quinolin-7-yl)oxy)ethyl)morpholine
R-1 Methanandamide phosphate
C23H40NO5P (441.2643960000001)
Floridanine
C21H31NO9 (441.19987160000005)
A pyrrolizine alkaloid that is onetine in which the hydroxy hydrogen has been replaced by an acetyl group. Origin: Plant; SubCategory_DNP: Alkaloids derived from ornithine, Pyrrolizidine alkaloids
(13R)-11alpha-acetoxy-2alpha-hydroxy-13-isobutyryloxyhetisane|trichodelphinine A
C26H35NO5 (441.25151000000005)
Ser His Ala Lys
Ala His Lys Ser
Ala His Ser Lys
Ala Lys His Ser
Ala Lys Ser His
Mebeverine metabolite (1-Butanol, 4-[ethyl[2-(4-methoxyphenyl)-1-methylethyl]amino]- glucuronide)
Ala Pro Arg Val
C19H35N7O5 (441.26995400000004)
Ala Pro Val Arg
C19H35N7O5 (441.26995400000004)
Ala Arg Pro Val
C19H35N7O5 (441.26995400000004)
Ala Arg Val Pro
C19H35N7O5 (441.26995400000004)
Ala Ser His Lys
Ala Ser Lys His
Ala Val Pro Arg
C19H35N7O5 (441.26995400000004)
Ala Val Arg Pro
C19H35N7O5 (441.26995400000004)
Gly His Lys Thr
Gly His Thr Lys
Gly Ile Pro Arg
C19H35N7O5 (441.26995400000004)
Gly Ile Arg Pro
C19H35N7O5 (441.26995400000004)
Gly Lys His Thr
Gly Lys Thr His
Gly Leu Pro Arg
C19H35N7O5 (441.26995400000004)
Gly Leu Arg Pro
C19H35N7O5 (441.26995400000004)
Gly Pro Ile Arg
C19H35N7O5 (441.26995400000004)
Gly Pro Leu Arg
C19H35N7O5 (441.26995400000004)
Gly Pro Arg Ile
C19H35N7O5 (441.26995400000004)
Gly Pro Arg Leu
C19H35N7O5 (441.26995400000004)
Gly Arg Ile Pro
C19H35N7O5 (441.26995400000004)
Gly Arg Leu Pro
C19H35N7O5 (441.26995400000004)
Gly Arg Pro Ile
C19H35N7O5 (441.26995400000004)
Gly Arg Pro Leu
C19H35N7O5 (441.26995400000004)
Gly Thr His Lys
Gly Thr Lys His
His Ala Lys Ser
His Ala Ser Lys
His Gly Lys Thr
His Gly Thr Lys
His Lys Ala Ser
His Lys Gly Thr
His Lys Ser Ala
His Lys Thr Gly
His Ser Ala Lys
His Ser Lys Ala
His Thr Gly Lys
His Thr Lys Gly
Ile Gly Pro Arg
C19H35N7O5 (441.26995400000004)
Ile Gly Arg Pro
C19H35N7O5 (441.26995400000004)
Ile Asn Pro Val
C20H35N5O6 (441.25872100000004)
Ile Asn Val Pro
C20H35N5O6 (441.25872100000004)
Ile Pro Gly Arg
C19H35N7O5 (441.26995400000004)
Ile Pro Asn Val
C20H35N5O6 (441.25872100000004)
Ile Pro Arg Gly
C19H35N7O5 (441.26995400000004)
Ile Pro Val Asn
C20H35N5O6 (441.25872100000004)
Ile Arg Gly Pro
C19H35N7O5 (441.26995400000004)
Ile Arg Pro Gly
C19H35N7O5 (441.26995400000004)
Ile Val Asn Pro
C20H35N5O6 (441.25872100000004)
Ile Val Pro Asn
C20H35N5O6 (441.25872100000004)
Lys Ala His Ser
Lys Ala Ser His
Lys Gly His Thr
Lys Gly Thr His
Lys His Ala Ser
Lys His Gly Thr
Lys His Ser Ala
Lys His Thr Gly
Lys Pro Pro Thr
C20H35N5O6 (441.25872100000004)
Lys Pro Thr Pro
C20H35N5O6 (441.25872100000004)
Lys Pro Val Val
Lys Ser Ala His
Lys Ser His Ala
Lys Thr Gly His
Lys Thr His Gly
Lys Thr Pro Pro
C20H35N5O6 (441.25872100000004)
Lys Val Pro Val
Lys Val Val Pro
Leu Gly Pro Arg
C19H35N7O5 (441.26995400000004)
Leu Gly Arg Pro
C19H35N7O5 (441.26995400000004)
Leu Asn Pro Val
C20H35N5O6 (441.25872100000004)
Leu Asn Val Pro
C20H35N5O6 (441.25872100000004)
Leu Pro Gly Arg
C19H35N7O5 (441.26995400000004)
Leu Pro Asn Val
C20H35N5O6 (441.25872100000004)
Leu Pro Arg Gly
C19H35N7O5 (441.26995400000004)
Leu Pro Val Asn
C20H35N5O6 (441.25872100000004)
Leu Arg Gly Pro
C19H35N7O5 (441.26995400000004)
Leu Arg Pro Gly
C19H35N7O5 (441.26995400000004)
Leu Val Asn Pro
C20H35N5O6 (441.25872100000004)
Leu Val Pro Asn
C20H35N5O6 (441.25872100000004)
Asn Ile Pro Val
C20H35N5O6 (441.25872100000004)
Asn Ile Val Pro
C20H35N5O6 (441.25872100000004)
Asn Leu Pro Val
C20H35N5O6 (441.25872100000004)
Asn Leu Val Pro
C20H35N5O6 (441.25872100000004)
Asn Pro Ile Val
C20H35N5O6 (441.25872100000004)
Asn Pro Leu Val
C20H35N5O6 (441.25872100000004)
Asn Pro Val Ile
C20H35N5O6 (441.25872100000004)
Asn Pro Val Leu
C20H35N5O6 (441.25872100000004)
Asn Val Ile Pro
C20H35N5O6 (441.25872100000004)
Asn Val Leu Pro
C20H35N5O6 (441.25872100000004)
Asn Val Pro Ile
C20H35N5O6 (441.25872100000004)
Asn Val Pro Leu
C20H35N5O6 (441.25872100000004)
Pro Ala Arg Val
C19H35N7O5 (441.26995400000004)
Pro Ala Val Arg
C19H35N7O5 (441.26995400000004)
Pro Gly Ile Arg
C19H35N7O5 (441.26995400000004)
Pro Gly Leu Arg
C19H35N7O5 (441.26995400000004)
Pro Gly Arg Ile
C19H35N7O5 (441.26995400000004)
Pro Gly Arg Leu
C19H35N7O5 (441.26995400000004)
Pro Ile Gly Arg
C19H35N7O5 (441.26995400000004)
Pro Ile Asn Val
C20H35N5O6 (441.25872100000004)
Pro Ile Arg Gly
C19H35N7O5 (441.26995400000004)
Pro Ile Val Asn
C20H35N5O6 (441.25872100000004)
Pro Lys Pro Thr
C20H35N5O6 (441.25872100000004)
Pro Lys Thr Pro
C20H35N5O6 (441.25872100000004)
Pro Lys Val Val
Pro Leu Gly Arg
C19H35N7O5 (441.26995400000004)
Pro Leu Asn Val
C20H35N5O6 (441.25872100000004)
Pro Leu Arg Gly
C19H35N7O5 (441.26995400000004)
Pro Leu Val Asn
C20H35N5O6 (441.25872100000004)
Pro Asn Ile Val
C20H35N5O6 (441.25872100000004)
Pro Asn Leu Val
C20H35N5O6 (441.25872100000004)
Pro Asn Val Ile
C20H35N5O6 (441.25872100000004)
Pro Asn Val Leu
C20H35N5O6 (441.25872100000004)
Pro Pro Lys Thr
C20H35N5O6 (441.25872100000004)
Pro Pro Gln Thr
Pro Pro Thr Lys
C20H35N5O6 (441.25872100000004)
Pro Pro Thr Gln
Pro Gln Pro Thr
Pro Gln Thr Pro
Pro Gln Val Val
C20H35N5O6 (441.25872100000004)
Pro Arg Ala Val
C19H35N7O5 (441.26995400000004)
Pro Arg Gly Ile
C19H35N7O5 (441.26995400000004)
Pro Arg Gly Leu
C19H35N7O5 (441.26995400000004)
Pro Arg Ile Gly
C19H35N7O5 (441.26995400000004)
Pro Arg Leu Gly
C19H35N7O5 (441.26995400000004)
Pro Arg Val Ala
C19H35N7O5 (441.26995400000004)
Pro Thr Lys Pro
C20H35N5O6 (441.25872100000004)
Pro Thr Pro Lys
C20H35N5O6 (441.25872100000004)
Pro Thr Pro Gln
Pro Thr Gln Pro
Pro Val Ala Arg
C19H35N7O5 (441.26995400000004)
Pro Val Ile Asn
C20H35N5O6 (441.25872100000004)
Pro Val Lys Val
Pro Val Leu Asn
C20H35N5O6 (441.25872100000004)
Pro Val Asn Ile
C20H35N5O6 (441.25872100000004)
Pro Val Asn Leu
C20H35N5O6 (441.25872100000004)
Pro Val Gln Val
C20H35N5O6 (441.25872100000004)
Pro Val Arg Ala
C19H35N7O5 (441.26995400000004)
Pro Val Val Lys
Pro Val Val Gln
C20H35N5O6 (441.25872100000004)
Gln Pro Pro Thr
Gln Pro Thr Pro
Gln Pro Val Val
C20H35N5O6 (441.25872100000004)
Gln Thr Pro Pro
Gln Val Pro Val
C20H35N5O6 (441.25872100000004)
Gln Val Val Pro
C20H35N5O6 (441.25872100000004)
Arg Ala Pro Val
C19H35N7O5 (441.26995400000004)
Arg Ala Val Pro
C19H35N7O5 (441.26995400000004)
Arg Gly Ile Pro
C19H35N7O5 (441.26995400000004)
Arg Gly Leu Pro
C19H35N7O5 (441.26995400000004)
Arg Gly Pro Ile
C19H35N7O5 (441.26995400000004)
Arg Gly Pro Leu
C19H35N7O5 (441.26995400000004)
Arg Ile Gly Pro
C19H35N7O5 (441.26995400000004)
Arg Ile Pro Gly
C19H35N7O5 (441.26995400000004)
Arg Leu Gly Pro
C19H35N7O5 (441.26995400000004)
Arg Leu Pro Gly
C19H35N7O5 (441.26995400000004)
Arg Pro Ala Val
C19H35N7O5 (441.26995400000004)
Arg Pro Gly Ile
C19H35N7O5 (441.26995400000004)
Arg Pro Gly Leu
C19H35N7O5 (441.26995400000004)
Arg Pro Ile Gly
C19H35N7O5 (441.26995400000004)
Arg Pro Leu Gly
C19H35N7O5 (441.26995400000004)
Arg Pro Val Ala
C19H35N7O5 (441.26995400000004)
Arg Val Ala Pro
C19H35N7O5 (441.26995400000004)
Arg Val Pro Ala
C19H35N7O5 (441.26995400000004)
Ser Ala His Lys
Ser Ala Lys His
Ser His Lys Ala
Ser Lys Ala His
Ser Lys His Ala
Thr Gly His Lys
Thr Gly Lys His
Thr His Gly Lys
Thr His Lys Gly
Thr Lys Gly His
Thr Lys His Gly
Thr Lys Pro Pro
C20H35N5O6 (441.25872100000004)
Thr Pro Lys Pro
C20H35N5O6 (441.25872100000004)
Thr Pro Pro Lys
C20H35N5O6 (441.25872100000004)
Thr Pro Pro Gln
Thr Pro Gln Pro
Thr Gln Pro Pro
Val Ala Pro Arg
C19H35N7O5 (441.26995400000004)
Val Ala Arg Pro
C19H35N7O5 (441.26995400000004)
Val Ile Asn Pro
C20H35N5O6 (441.25872100000004)
Val Ile Pro Asn
C20H35N5O6 (441.25872100000004)
Val Lys Pro Val
Val Lys Val Pro
Val Leu Asn Pro
C20H35N5O6 (441.25872100000004)
Val Leu Pro Asn
C20H35N5O6 (441.25872100000004)
Val Asn Ile Pro
C20H35N5O6 (441.25872100000004)
Val Asn Leu Pro
C20H35N5O6 (441.25872100000004)
Val Asn Pro Ile
C20H35N5O6 (441.25872100000004)
Val Asn Pro Leu
C20H35N5O6 (441.25872100000004)
Val Pro Ala Arg
C19H35N7O5 (441.26995400000004)
Val Pro Ile Asn
C20H35N5O6 (441.25872100000004)
Val Pro Lys Val
Val Pro Leu Asn
C20H35N5O6 (441.25872100000004)
Val Pro Asn Ile
C20H35N5O6 (441.25872100000004)
Val Pro Asn Leu
C20H35N5O6 (441.25872100000004)
Val Pro Gln Val
C20H35N5O6 (441.25872100000004)
Val Pro Arg Ala
C19H35N7O5 (441.26995400000004)
Val Pro Val Lys
Val Pro Val Gln
C20H35N5O6 (441.25872100000004)
Val Gln Pro Val
C20H35N5O6 (441.25872100000004)
Val Gln Val Pro
C20H35N5O6 (441.25872100000004)
Val Arg Ala Pro
C19H35N7O5 (441.26995400000004)
Val Arg Pro Ala
C19H35N7O5 (441.26995400000004)
Val Val Lys Pro
Val Val Pro Lys
Val Val Pro Gln
C20H35N5O6 (441.25872100000004)
Val Val Gln Pro
C20H35N5O6 (441.25872100000004)
Leukotriene E3
C23H39NO5S (441.25488040000005)
A leukotriene that is leukotriene E4 in which the non-conjugated double bond has been reduced to a single bond.
cyclopropyl methyl amide
C27H39NO4 (441.28789340000003)
N-(α-Linolenoyl) Tyrosine
C27H39NO4 (441.28789340000003)
Vilazodone
D018377 - Neurotransmitter Agents > D018490 - Serotonin Agents > D017367 - Selective Serotonin Reuptake Inhibitors D002491 - Central Nervous System Agents > D011619 - Psychotropic Drugs > D000928 - Antidepressive Agents D018377 - Neurotransmitter Agents > D018490 - Serotonin Agents > D017366 - Serotonin Receptor Agonists D018377 - Neurotransmitter Agents > D014179 - Neurotransmitter Uptake Inhibitors C78272 - Agent Affecting Nervous System > C265 - Antidepressant Agent N - Nervous system > N06 - Psychoanaleptics > N06A - Antidepressants D049990 - Membrane Transport Modulators Vilazodone (EMD 68843; SB 659746A) is a potent, selective and orally active?serotonin?reuptake inhibitor (SSRI) and partial?5-HT1A receptor agonist. Vilazodone exhibits antidepressant efficacy in vivo can be used for the research of major depressive disorder (MDD) and affective disorders[1][2].
LPE O-15:0;O
C20H44NO7P (441.28552440000004)
[1,1-Bis(hydroxymethyl)-3-(4-octylphenyl)propyl]carbamic acid Phenylmethyl Ester
C27H39NO4 (441.28789340000003)
PHENOL, 2-(2H-BENZOTRIAZOL-2-YL)-6-(1-METHYL-1-PHENYLETHYL)-4-(1,1,3,3-TETRAMETHYLBUTYL)-
LY2109761
6-[2-[4-(4-fluorophenyl)-5-(methoxymethyl)-2,6-di(propan-2-yl)pyridin-3-yl]ethenyl]-4-hydroxyoxan-2-one
Deflazacort
H - Systemic hormonal preparations, excl. sex hormones and insulins > H02 - Corticosteroids for systemic use > H02A - Corticosteroids for systemic use, plain > H02AB - Glucocorticoids C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C1636 - Therapeutic Steroid Hormone C308 - Immunotherapeutic Agent > C574 - Immunosuppressant > C211 - Therapeutic Corticosteroid D007155 - Immunologic Factors > D007166 - Immunosuppressive Agents D000893 - Anti-Inflammatory Agents
3-Hydroxy-piperidine-1-carboxylic acid tert-butyl ester
Bisoprolol monofumarate
D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents > D013565 - Sympatholytics D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents > D018674 - Adrenergic Antagonists D002317 - Cardiovascular Agents > D000959 - Antihypertensive Agents
5-Methyl-3-(9-oxo-1,8-diaza-tricyclo[10.6.1.013,18]nonadeca-12(19),13,15,17-tetraen-10-ylcarbamoyl)-hexanoic acid
C25H35N3O4 (441.26274300000006)
N-(4-Morpholine)carbonyl-B-(1-naphthyl)-L-alanine-L-leucine boronic acid
Lisinopril diydrate
C21H35N3O7 (441.24748800000003)
D004791 - Enzyme Inhibitors > D011480 - Protease Inhibitors > D000806 - Angiotensin-Converting Enzyme Inhibitors C78274 - Agent Affecting Cardiovascular System > C270 - Antihypertensive Agent C471 - Enzyme Inhibitor > C783 - Protease Inhibitor > C247 - ACE Inhibitor D002317 - Cardiovascular Agents > D000959 - Antihypertensive Agents D020011 - Protective Agents > D002316 - Cardiotonic Agents
6-[2-[4-(4-Fluorophenyl)-2,6-diisopropyl-5-(methoxymethyl)-3-pyridyl]vinyl]-4-hydroxy-tetrahydropyran-2-one
Militarinone E, (rel)-
C26H35NO5 (441.25151000000005)
A natural product found in Isaria farinosa.
Militarinone F, (rel)-
C26H35NO5 (441.25151000000005)
A natural product found in Isaria farinosa.
(3S)-3-(1,3-benzodioxol-5-yl)-1-(3,5-dimethyl-1-piperidinyl)-3-(2-hydroxy-4,6-dimethoxyphenyl)-1-propanone
5,7-Dimethyl-[1,2,4]triazolo[1,5-a]pyrimidine-2-carboxylic acid [2-[2-(3,4-diethoxyphenyl)ethylamino]-2-oxoethyl] ester
C22H27N5O5 (441.20120920000005)
Lys-Thr-Pro-Pro
C20H35N5O6 (441.25872100000004)
A tetrapeptide composed of L-lysine, L-threonine and two L-proline units joined in sequence by peptide linkages.
3alpha,7alpha-Dihydroxy-5beta-cholane-24-sulfonate
C24H41O5S- (441.26745560000006)
D005765 - Gastrointestinal Agents > D001647 - Bile Acids and Salts D005765 - Gastrointestinal Agents > D002793 - Cholic Acids
(1R,4S,6R,7R,11Z)-4-hydroxy-4-[(1R)-1-hydroxyethyl]-6,7,14-trimethyl-3,8,17-trioxo-2,9-dioxa-14-azabicyclo[9.5.1]heptadec-11-en-7-yl acetate
C21H31NO9 (441.19987160000005)
2-[(2R,5R,6S)-6-(hydroxymethyl)-5-[[(2-methoxyanilino)-oxomethyl]amino]-2-oxanyl]-N-[(1R)-1-phenylethyl]acetamide
(1R,9S,10S,11S)-5-(cyclopenten-1-yl)-10-(hydroxymethyl)-N,N-dimethyl-12-(oxan-4-ylmethyl)-6-oxo-7,12-diazatricyclo[7.2.1.02,7]dodeca-2,4-diene-11-carboxamide
C25H35N3O4 (441.26274300000006)
(2S,3R)-2-[[(2-fluorophenyl)methyl-methylamino]methyl]-5-[(2S)-1-hydroxypropan-2-yl]-3-methyl-8-[(E)-prop-1-enyl]-3,4-dihydro-2H-pyrido[2,3-b][1,5]oxazocin-6-one
C25H32FN3O3 (441.24275739999996)
(2R,3S)-2-[[(2-fluorophenyl)methyl-methylamino]methyl]-5-[(2S)-1-hydroxypropan-2-yl]-3-methyl-8-[(E)-prop-1-enyl]-3,4-dihydro-2H-pyrido[2,3-b][1,5]oxazocin-6-one
C25H32FN3O3 (441.24275739999996)
(2R,3R)-2-[[(2-fluorophenyl)methyl-methylamino]methyl]-5-[(2S)-1-hydroxypropan-2-yl]-3-methyl-8-[(E)-prop-1-enyl]-3,4-dihydro-2H-pyrido[2,3-b][1,5]oxazocin-6-one
C25H32FN3O3 (441.24275739999996)
(2R,3R)-2-[[(2-fluorophenyl)methyl-methylamino]methyl]-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-8-[(E)-prop-1-enyl]-3,4-dihydro-2H-pyrido[2,3-b][1,5]oxazocin-6-one
C25H32FN3O3 (441.24275739999996)
(2R,3S)-5-[(2S)-1-hydroxypropan-2-yl]-8-(2-methoxyphenyl)-3-methyl-2-[[methyl(propyl)amino]methyl]-3,4-dihydro-2H-pyrido[2,3-b][1,5]oxazocin-6-one
C25H35N3O4 (441.26274300000006)
(2R,3S)-2-[[(4-fluorophenyl)methyl-methylamino]methyl]-5-[(2S)-1-hydroxypropan-2-yl]-3-methyl-8-[(E)-prop-1-enyl]-3,4-dihydro-2H-pyrido[2,3-b][1,5]oxazocin-6-one
C25H32FN3O3 (441.24275739999996)
N-[(4S,7S,8S)-8-methoxy-4,7,10-trimethyl-11-oxo-5-propyl-2-oxa-5,10-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]methanesulfonamide
C21H35N3O5S (441.2297300000001)
N-[(4S,7R,8R)-8-methoxy-4,7,10-trimethyl-11-oxo-5-propyl-2-oxa-5,10-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]methanesulfonamide
C21H35N3O5S (441.2297300000001)
N-[(4R,7S,8R)-8-methoxy-4,7,10-trimethyl-11-oxo-5-propyl-2-oxa-5,10-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]methanesulfonamide
C21H35N3O5S (441.2297300000001)
N-[(5R,6R,9S)-5-methoxy-3,6,8,9-tetramethyl-2-oxo-11-oxa-3,8-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]-2-pyrazinecarboxamide
N-[(5R,6S,9R)-5-methoxy-3,6,8,9-tetramethyl-2-oxo-11-oxa-3,8-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]-2-pyrazinecarboxamide
N-[(5R,6R,9R)-5-methoxy-3,6,9-trimethyl-2-oxo-8-propyl-11-oxa-3,8-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]methanesulfonamide
C21H35N3O5S (441.2297300000001)
N-[(5S,6S,9R)-5-methoxy-3,6,9-trimethyl-2-oxo-8-propyl-11-oxa-3,8-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]methanesulfonamide
C21H35N3O5S (441.2297300000001)
N-[(5S,6R,9S)-5-methoxy-3,6,9-trimethyl-2-oxo-8-propyl-11-oxa-3,8-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]methanesulfonamide
C21H35N3O5S (441.2297300000001)
2-[(2S,5R,6S)-6-(hydroxymethyl)-5-[[(2-methoxyanilino)-oxomethyl]amino]-2-oxanyl]-N-[(1R)-1-phenylethyl]acetamide
2-[(2R,5R,6S)-6-(hydroxymethyl)-5-[[(2-methoxyanilino)-oxomethyl]amino]-2-oxanyl]-N-[(1S)-1-phenylethyl]acetamide
2-[(2S,5S,6R)-6-(hydroxymethyl)-5-[[(2-methoxyanilino)-oxomethyl]amino]-2-oxanyl]-N-[(1S)-1-phenylethyl]acetamide
2-[(2R,5S,6R)-6-(hydroxymethyl)-5-[[(2-methoxyanilino)-oxomethyl]amino]-2-oxanyl]-N-[(1S)-1-phenylethyl]acetamide
2-[(2R,5R,6R)-6-(hydroxymethyl)-5-[[(2-methoxyanilino)-oxomethyl]amino]-2-oxanyl]-N-[(1S)-1-phenylethyl]acetamide
2-[(2R,5S,6S)-6-(hydroxymethyl)-5-[[(2-methoxyanilino)-oxomethyl]amino]-2-oxanyl]-N-[(1R)-1-phenylethyl]acetamide
(2R,3R)-2-(hydroxymethyl)-1-(oxane-4-carbonyl)-N-propan-2-yl-3-[4-[(E)-prop-1-enyl]phenyl]-1,6-diazaspiro[3.3]heptane-6-carboxamide
C25H35N3O4 (441.26274300000006)
(2S,3S)-2-[[(2-fluorophenyl)methyl-methylamino]methyl]-5-[(2S)-1-hydroxypropan-2-yl]-3-methyl-8-[(E)-prop-1-enyl]-3,4-dihydro-2H-pyrido[2,3-b][1,5]oxazocin-6-one
C25H32FN3O3 (441.24275739999996)
(2S,3S)-2-[[(2-fluorophenyl)methyl-methylamino]methyl]-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-8-[(E)-prop-1-enyl]-3,4-dihydro-2H-pyrido[2,3-b][1,5]oxazocin-6-one
C25H32FN3O3 (441.24275739999996)
(2S,3R)-2-[[(2-fluorophenyl)methyl-methylamino]methyl]-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-8-[(E)-prop-1-enyl]-3,4-dihydro-2H-pyrido[2,3-b][1,5]oxazocin-6-one
C25H32FN3O3 (441.24275739999996)
(2R,3S)-2-[[(2-fluorophenyl)methyl-methylamino]methyl]-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-8-[(E)-prop-1-enyl]-3,4-dihydro-2H-pyrido[2,3-b][1,5]oxazocin-6-one
C25H32FN3O3 (441.24275739999996)
N-[(4R,7R,8R)-8-methoxy-4,7,10-trimethyl-11-oxo-5-propyl-2-oxa-5,10-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]methanesulfonamide
C21H35N3O5S (441.2297300000001)
N-[(4R,7S,8S)-8-methoxy-4,7,10-trimethyl-11-oxo-5-propyl-2-oxa-5,10-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]methanesulfonamide
C21H35N3O5S (441.2297300000001)
N-[(4S,7R,8S)-8-methoxy-4,7,10-trimethyl-11-oxo-5-propyl-2-oxa-5,10-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]methanesulfonamide
C21H35N3O5S (441.2297300000001)
N-[(5R,6R,9R)-5-methoxy-3,6,8,9-tetramethyl-2-oxo-11-oxa-3,8-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]-2-pyrazinecarboxamide
N-[(5S,6S,9S)-5-methoxy-3,6,8,9-tetramethyl-2-oxo-11-oxa-3,8-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]-2-pyrazinecarboxamide
N-[(5S,6R,9R)-5-methoxy-3,6,8,9-tetramethyl-2-oxo-11-oxa-3,8-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]-2-pyrazinecarboxamide
N-[(5S,6R,9S)-5-methoxy-3,6,8,9-tetramethyl-2-oxo-11-oxa-3,8-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]-2-pyrazinecarboxamide
N-[(5S,6S,9S)-5-methoxy-3,6,9-trimethyl-2-oxo-8-propyl-11-oxa-3,8-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]methanesulfonamide
C21H35N3O5S (441.2297300000001)
N-[(5R,6R,9S)-5-methoxy-3,6,9-trimethyl-2-oxo-8-propyl-11-oxa-3,8-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]methanesulfonamide
C21H35N3O5S (441.2297300000001)
N-[(5R,6S,9R)-5-methoxy-3,6,9-trimethyl-2-oxo-8-propyl-11-oxa-3,8-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]methanesulfonamide
C21H35N3O5S (441.2297300000001)
2-[(2R,5S,6R)-6-(hydroxymethyl)-5-[[(2-methoxyanilino)-oxomethyl]amino]-2-oxanyl]-N-[(1R)-1-phenylethyl]acetamide
2-[(2S,5R,6S)-6-(hydroxymethyl)-5-[[(2-methoxyanilino)-oxomethyl]amino]-2-oxanyl]-N-[(1S)-1-phenylethyl]acetamide
2-[(2S,5S,6R)-6-(hydroxymethyl)-5-[[(2-methoxyanilino)-oxomethyl]amino]-2-oxanyl]-N-[(1R)-1-phenylethyl]acetamide
2-[(2S,5S,6S)-6-(hydroxymethyl)-5-[[(2-methoxyanilino)-oxomethyl]amino]-2-oxanyl]-N-[(1S)-1-phenylethyl]acetamide
2-[(2S,5S,6S)-6-(hydroxymethyl)-5-[[(2-methoxyanilino)-oxomethyl]amino]-2-oxanyl]-N-[(1R)-1-phenylethyl]acetamide
2-[(2R,5R,6R)-6-(hydroxymethyl)-5-[[(2-methoxyanilino)-oxomethyl]amino]-2-oxanyl]-N-[(1R)-1-phenylethyl]acetamide
2-[(2R,5S,6S)-6-(hydroxymethyl)-5-[[(2-methoxyanilino)-oxomethyl]amino]-2-oxanyl]-N-[(1S)-1-phenylethyl]acetamide
2-[(2S,5R,6R)-6-(hydroxymethyl)-5-[[(2-methoxyanilino)-oxomethyl]amino]-2-oxanyl]-N-[(1R)-1-phenylethyl]acetamide
2-[(2S,5R,6R)-6-(hydroxymethyl)-5-[[(2-methoxyanilino)-oxomethyl]amino]-2-oxanyl]-N-[(1S)-1-phenylethyl]acetamide
(1S,9R,10R,11R)-5-(cyclopenten-1-yl)-10-(hydroxymethyl)-N,N-dimethyl-12-(oxan-4-ylmethyl)-6-oxo-7,12-diazatricyclo[7.2.1.02,7]dodeca-2,4-diene-11-carboxamide
C25H35N3O4 (441.26274300000006)
[(1R)-1-[(2,5-difluorophenyl)methyl]-7-methoxy-9-methyl-1-spiro[2,3-dihydro-1H-pyrido[3,4-b]indole-4,4-piperidine]yl]methanol
C25H29F2N3O2 (441.22277180000003)
[(1S)-1-[(2,5-difluorophenyl)methyl]-7-methoxy-9-methyl-1-spiro[2,3-dihydro-1H-pyrido[3,4-b]indole-4,4-piperidine]yl]methanol
C25H29F2N3O2 (441.22277180000003)
(2S,3R)-2-(hydroxymethyl)-1-(oxane-4-carbonyl)-N-propan-2-yl-3-[4-[(E)-prop-1-enyl]phenyl]-1,6-diazaspiro[3.3]heptane-6-carboxamide
C25H35N3O4 (441.26274300000006)
2-Amino-3-[(3-dodecanoyloxy-2-hydroxypropoxy)-hydroxyphosphoryl]oxypropanoic acid
C18H36NO9P (441.2127576000001)
2-[2,3-Di(trimethylsilyloxy)butoxy]-N-[2-(ethylamino)ethyl]-3-pyridinecarboxamide
C20H39N3O4Si2 (441.24789740000006)
1-dodecanoyl-glycero-3-phosphoserine
C18H36NO9P (441.2127576000001)
T0467
C24H26F3N5 (441.21401920000005)
T0467 activates parkin mitochondrial translocation in a PINK1-dependent manner in vitro. T0467 do not induce mitochondrial accumulation of PINK1in dopaminergic neurons. T0467 is a potential compound for PINK1-Parkin signaling activation, and can be used for parkinson's disease and related disorders research[1].
(1r,2r,10s,11r,13s,14r,15s)-14-hydroxy-15-methyl-6-azatetracyclo[8.6.0.0¹,⁶.0²,¹³]hexadecan-11-yl (2e)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate
C26H35NO5 (441.25151000000005)
1,4-dihydroxy-5-(4-hydroxycyclohex-1-en-1-yl)-3-(6,8,10-trimethyldodeca-2,4,6-trienoyl)pyridin-2-one
C26H35NO5 (441.25151000000005)
(1r,2r,4s,5r,8s,10r,12r,13s,14r,16s,17r,19s)-16-(acetyloxy)-11-ethyl-5-methyl-18-methylidene-9-oxa-11-azaheptacyclo[15.2.1.0¹,¹⁴.0²,¹².0⁴,¹³.0⁵,¹⁰.0⁸,¹³]icosan-19-yl acetate
C26H35NO5 (441.25151000000005)
(1r,4r,6r,7r,11z)-4-hydroxy-4-[(1s)-1-hydroxyethyl]-6,7,14-trimethyl-3,8,17-trioxo-2,9-dioxa-14-azabicyclo[9.5.1]heptadec-11-en-7-yl acetate
C21H31NO9 (441.19987160000005)
methyl (1r,5s,6r,9r,10s,13r,19r,21r)-9-[(acetyloxy)methyl]-21-hydroxy-5-methyl-20-oxa-3-azaheptacyclo[11.5.2.1⁶,¹⁰.0¹,⁹.0²,⁶.0¹³,¹⁹.0¹⁶,¹⁹]henicosa-2,16-diene-17-carboxylate
[8-(4,8-dimethylnona-3,7-dien-1-yl)-5,7-dihydroxy-8-methyl-3-oxo-1h,6h,7h,9h-cyclohexa[e]isoindol-2-yl]acetic acid
C26H35NO5 (441.25151000000005)
4-hydroxy-4-(1-hydroxyethyl)-6,7,14-trimethyl-3,8,17-trioxo-2,9-dioxa-14-azabicyclo[9.5.1]heptadec-11-en-7-yl acetate
C21H31NO9 (441.19987160000005)
(3s,3ar,4s,6as,14r,15ar)-1-hydroxy-4,5,8-trimethyl-3-(2-methylpropyl)-14-(2-oxopropyl)-3h,3ah,4h,6ah,9h,10h,11h,13h,14h-cycloundeca[d]isoindole-12,15-dione
C27H39NO4 (441.28789340000003)
(1r,2s,7r,8ar)-7-[(3e)-3-(hydroxyimino)prop-1-en-2-yl]-7-methoxy-1,8a-dimethyl-6-oxo-2,8-dihydro-1h-naphthalen-2-yl (2e,4e,6s)-4,6-dimethylocta-2,4-dienoate
C26H35NO5 (441.25151000000005)
n-(3-{7,15-dihydroxy-9-oxo-10,17-dioxatricyclo[11.3.1.0³,⁸]heptadeca-3,5,7-trien-11-yl}prop-1-en-1-yl)hepta-2,4-dienimidic acid
(6e)-1-[(5s)-2,4-dihydroxy-5-[(s)-hydroxy(phenyl)methyl]-5h-pyrrol-3-yl]-4,6,8,10-tetramethyldodec-6-en-1-one
C27H39NO4 (441.28789340000003)
1,4-dihydroxy-5-[(1s,4s)-7-oxabicyclo[2.2.1]heptan-1-yl]-3-[(2e,4e,6e,8r,10r)-6,8,10-trimethyldodeca-2,4,6-trienoyl]pyridin-2-one
C26H35NO5 (441.25151000000005)
4,6'-dihydroxy-2',5',5',8'a-tetramethyl-7-(2-oxopropyl)-3,3',4',4'a,6',7',8,8'-octahydro-2'h-spiro[furo[2,3-e]isoindole-2,1'-naphthalen]-6-one
C26H35NO5 (441.25151000000005)
(2s)-2-{[(2s)-2-{[(2s,3r)-3-amino-1,2-dihydroxy-4-phenylbutylidene]amino}-1-hydroxy-3-methylbutylidene]amino}-3-phenylpropanoic acid
(3e,5e)-14-hydroxy-3,7,11-trimethyltetradeca-3,5-dien-1-yl 2-(hydroxymethyl)-1h-indole-3-carboxylate
C27H39NO4 (441.28789340000003)
(1r,6r,7r)-4-hydroxy-4-(1-hydroxyethyl)-6,7,14-trimethyl-3,8,17-trioxo-2,9-dioxa-14-azabicyclo[9.5.1]heptadec-11-en-7-yl acetate
C21H31NO9 (441.19987160000005)
9-ethyl-4,5,9-trihydroxy-4-isopropyl-8-methyl-2,7,11-trioxa-16-azatricyclo[11.5.1.0¹⁶,¹⁹]nonadec-13-ene-3,6,10-trione
C21H31NO9 (441.19987160000005)
1,4-dihydroxy-5-{7-oxabicyclo[2.2.1]heptan-1-yl}-3-(6,8,10-trimethyldodeca-2,4,6-trienoyl)pyridin-2-one
C26H35NO5 (441.25151000000005)
2-hydroxy-1-{11-hydroxy-8-isopropyl-18-methoxy-2,5-dimethyl-19-oxa-15-azapentacyclo[11.6.1.0²,¹⁰.0⁵,⁹.0¹⁷,²⁰]icosa-8,13(20),14,16-tetraen-16-yl}ethanone
C26H35NO5 (441.25151000000005)
1-{2-amino-5-oxo-3ah,6h,6ah-furo[3,2-b]furan-3-yl}-3,7,9,11-tetramethylhexadeca-5,7,11,13-tetraene-1,2-dione
C26H35NO5 (441.25151000000005)
1-hydroxy-4,5,8-trimethyl-3-(2-methylpropyl)-14-(2-oxopropyl)-3h,3ah,4h,6ah,9h,10h,11h,13h,14h-cycloundeca[d]isoindole-12,15-dione
C27H39NO4 (441.28789340000003)
7-[3-(hydroxyimino)prop-1-en-2-yl]-7-methoxy-1,8a-dimethyl-6-oxo-2,8-dihydro-1h-naphthalen-2-yl 4,6-dimethylocta-2,4-dienoate
C26H35NO5 (441.25151000000005)
2-({2-[(3-amino-1,2-dihydroxy-4-phenylbutylidene)amino]-1-hydroxy-3-methylbutylidene}amino)-3-phenylpropanoic acid
14-hydroxy-3,7,11-trimethyltetradeca-3,5-dien-1-yl 2-(hydroxymethyl)-1h-indole-3-carboxylate
C27H39NO4 (441.28789340000003)
(2r,2'r,4'as,6'r,8'as)-4,6'-dihydroxy-2',5',5',8'a-tetramethyl-7-(2-oxopropyl)-3,3',4',4'a,6',7',8,8'-octahydro-2'h-spiro[furo[2,3-e]isoindole-2,1'-naphthalen]-6-one
C26H35NO5 (441.25151000000005)
[(7s,8r)-8-[(3e)-4,8-dimethylnona-3,7-dien-1-yl]-5,7-dihydroxy-8-methyl-3-oxo-1h,6h,7h,9h-cyclohexa[e]isoindol-2-yl]acetic acid
C26H35NO5 (441.25151000000005)
(1r,2r,10s,11r,13s,14s,15s)-14-hydroxy-15-methyl-6-azatetracyclo[8.6.0.0¹,⁶.0²,¹³]hexadecan-11-yl (2e)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate
C26H35NO5 (441.25151000000005)
(1r,4r,5r,8r,9s,19r)-9-ethyl-4,5,9-trihydroxy-4-isopropyl-8-methyl-2,7,11-trioxa-16-azatricyclo[11.5.1.0¹⁶,¹⁹]nonadec-13-ene-3,6,10-trione
C21H31NO9 (441.19987160000005)
1-{2,4-dihydroxy-5-[hydroxy(phenyl)methyl]-5h-pyrrol-3-yl}-4,6,8,10-tetramethyldodec-6-en-1-one
C27H39NO4 (441.28789340000003)
(3r,5e,7e,9r,11e,13z)-1-[(3as,6ar)-2-amino-5-oxo-3ah,6h,6ah-furo[3,2-b]furan-3-yl]-3,7,9,11-tetramethylhexadeca-5,7,11,13-tetraene-1,2-dione
C26H35NO5 (441.25151000000005)
(e,2z,4z)-n-[(1e)-3-{7,15-dihydroxy-9-oxo-10,17-dioxatricyclo[11.3.1.0³,⁸]heptadeca-3,5,7-trien-11-yl}prop-1-en-1-yl]hepta-2,4-dienimidic acid
(e,2z,4z)-n-[(1e)-3-[(1s,11s,13r,15r)-7,15-dihydroxy-9-oxo-10,17-dioxatricyclo[11.3.1.0³,⁸]heptadeca-3,5,7-trien-11-yl]prop-1-en-1-yl]hepta-2,4-dienimidic acid
2-hydroxy-1-[(1r,2r,5r,10r,11s,18r)-11-hydroxy-8-isopropyl-18-methoxy-2,5-dimethyl-19-oxa-15-azapentacyclo[11.6.1.0²,¹⁰.0⁵,⁹.0¹⁷,²⁰]icosa-8,13(20),14,16-tetraen-16-yl]ethanone
C26H35NO5 (441.25151000000005)
14-hydroxy-15-methyl-6-azatetracyclo[8.6.0.0¹,⁶.0²,¹³]hexadecan-11-yl 3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate
C26H35NO5 (441.25151000000005)
(4s,6r,7r,11z)-4-hydroxy-4-[(1s)-1-hydroxyethyl]-6,7,14-trimethyl-3,8,17-trioxo-2,9-dioxa-14-azabicyclo[9.5.1]heptadec-11-en-7-yl acetate
C21H31NO9 (441.19987160000005)
(1r,4r,5s,8r,9s,19r)-9-ethyl-4,5,9-trihydroxy-4-isopropyl-8-methyl-2,7,11-trioxa-16-azatricyclo[11.5.1.0¹⁶,¹⁹]nonadec-13-ene-3,6,10-trione
C21H31NO9 (441.19987160000005)
2-hydroxy-1-[(1r,2r,5r,10r,11s,18s)-11-hydroxy-8-isopropyl-18-methoxy-2,5-dimethyl-19-oxa-15-azapentacyclo[11.6.1.0²,¹⁰.0⁵,⁹.0¹⁷,²⁰]icosa-8,13(20),14,16-tetraen-16-yl]ethanone
C26H35NO5 (441.25151000000005)