Lisinopril diydrate (BioDeep_00000858877)
代谢物信息卡片
化学式: C21H35N3O7 (441.24748800000003)
中文名称: 赖诺普利 二水合物
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1CC(N(C1)C(=O)C(CCCCN)NC(CCC2=CC=CC=C2)C(=O)O)C(=O)O.O.O
InChI: /m0../s1
描述信息
D004791 - Enzyme Inhibitors > D011480 - Protease Inhibitors > D000806 - Angiotensin-Converting Enzyme Inhibitors
C78274 - Agent Affecting Cardiovascular System > C270 - Antihypertensive Agent
C471 - Enzyme Inhibitor > C783 - Protease Inhibitor > C247 - ACE Inhibitor
D002317 - Cardiovascular Agents > D000959 - Antihypertensive Agents
D020011 - Protective Agents > D002316 - Cardiotonic Agents
同义名列表
2 个代谢物同义名
数据库引用编号
6 个数据库交叉引用编号
- ChEBI: CHEBI:6503
- KEGGdrug: D00362
- PubChem: 5362118
- ChEMBL: CHEMBL419213
- MeSH: Lisinopril
- CAS: 83915-83-7
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Juan Cruz Carrizo, Sung Vo Duy, Gabriel Munoz, Guido Marconi, María Valeria Amé, Sébastien Sauvé. Suspect screening of pharmaceuticals, illicit drugs, pesticides, and other emerging contaminants in Argentinean Piaractus mesopotamicus, a fish species used for local consumption and export.
Chemosphere.
2022 Dec; 309(Pt 1):136769. doi:
10.1016/j.chemosphere.2022.136769
. [PMID: 36209849] - Stephen Y Wang, Jonathan M Hanna, Prajesh Gongal, Oyere K Onuma, Michael G Nanna. Choice of antihypertensive agent in isolated systolic hypertension and isolated diastolic hypertension: A secondary analysis of the ALLHAT trial.
American heart journal.
2022 Dec; 254(?):30-34. doi:
10.1016/j.ahj.2022.07.006
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Journal of food biochemistry.
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Inflammopharmacology.
2022 Oct; 30(5):1909-1926. doi:
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BMC pharmacology & toxicology.
2022 07; 23(1):45. doi:
10.1186/s40360-022-00590-6
. [PMID: 35794660] - Feng Gao, Wei Dong, Pengyuan Liu, Jayashree Narayanan, Brian L Fish, Elizabeth R Jacobs, Meetha Medhora. Molecular Changes in miRNA in Irradiated Rat Kidneys: Role of miR-34a and its Vascular Targets in the Notch Pathway.
Radiation research.
2021 12; 196(6):611-622. doi:
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Journal of cardiovascular pharmacology.
2021 11; 78(5):e738-e742. doi:
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Journal of the American College of Cardiology.
2021 10; 78(17):1671-1678. doi:
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Translational research : the journal of laboratory and clinical medicine.
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American journal of physiology. Renal physiology.
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Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.
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Acta chimica Slovenica.
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Clinical and translational science.
2021 03; 14(2):476-480. doi:
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PloS one.
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2021; 21(1):173-182. doi:
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Journal of hypertension.
2020 05; 38(5):954-960. doi:
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Endocrine.
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"
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PloS one.
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The American journal of case reports.
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Metabolomics : Official journal of the Metabolomic Society.
2019 10; 15(10):133. doi:
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Kidney international.
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Kidney international.
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BMJ case reports.
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Clinical pharmacokinetics.
2019 09; 58(9):1205-1214. doi:
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. [PMID: 30968335] - Tine A Bækdal, Jeanett Borregaard, Cilie W Hansen, Mette Thomsen, Thomas W Anderson. Effect of Oral Semaglutide on the Pharmacokinetics of Lisinopril, Warfarin, Digoxin, and Metformin in Healthy Subjects.
Clinical pharmacokinetics.
2019 09; 58(9):1193-1203. doi:
10.1007/s40262-019-00756-2
. [PMID: 30945118] - Shima Mehrvar, Mette Funding la Cour, Meetha Medhora, Amadou K S Camara, Mahsa Ranji. Optical Metabolic Imaging for Assessment of Radiation-Induced Injury to Rat Kidney and Mitigation by Lisinopril.
Annals of biomedical engineering.
2019 Jul; 47(7):1564-1574. doi:
10.1007/s10439-019-02255-8
. [PMID: 30963380] - I V Sergienko, A A Ansheles, О М Drapkina, N B Gornyakova, M Yu Zubareva, R N Shepel, V V Kuharchuk, S A Boytsov. ANICHKOV study: the effect of combined hypotensive and lipid-lowering therapy on cardiovascular complications in patients of high and very high risk.
Terapevticheskii arkhiv.
2019 May; 91(4):90-98. doi:
10.26442/00403660.2019.04.000104
. [PMID: 31094482] - Yuko Shima, Koichi Nakanishi, Mayumi Sako, Mari Saito-Oba, Yuko Hamasaki, Hiroshi Hataya, Masataka Honda, Koichi Kamei, Kenji Ishikura, Shuichi Ito, Hiroshi Kaito, Ryojiro Tanaka, Kandai Nozu, Hidefumi Nakamura, Yasuo Ohashi, Kazumoto Iijima, Norishige Yoshikawa. Lisinopril versus lisinopril and losartan for mild childhood IgA nephropathy: a randomized controlled trial (JSKDC01 study).
Pediatric nephrology (Berlin, Germany).
2019 05; 34(5):837-846. doi:
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. [PMID: 30284023] - Kyle Johnson, Suzanne Oparil, Barry R Davis, Larisa G Tereshchenko. Prevention of Heart Failure in Hypertension-Disentangling the Role of Evolving Left Ventricular Hypertrophy and Blood Pressure Lowering: The ALLHAT Study.
Journal of the American Heart Association.
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. [PMID: 30943832] - Terence T Sio, Pamela J Atherton, Levi D Pederson, W Ken Zhen, Robert W Mutter, Yolanda I Garces, Daniel J Ma, James L Leenstra, Jean-Claude M Rwigema, Shaker Dakhil, James D Bearden, Sonja J van der Veen, Apar K Ganti, Steven E Schild, Robert C Miller. Daily Lisinopril vs Placebo for Prevention of Chemoradiation-Induced Pulmonary Distress in Patients With Lung Cancer (Alliance MC1221): A Pilot Double-Blind Randomized Trial.
International journal of radiation oncology, biology, physics.
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Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia.
2019 Mar; 30(2):531-536. doi:
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The American journal of medicine.
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Journal of dietary supplements.
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British journal of clinical pharmacology.
2018 11; 84(11):2502-2521. doi:
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. [PMID: 29971804] - Noushin Rastkari, Reza Ahmadkhaniha. Development and validation of a high-performance liquid chromatography method for determination of lisinopril in human plasma by magnetic solid-phase extraction and pre-column derivatization.
Biomedical chromatography : BMC.
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Journal of the American Society of Nephrology : JASN.
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Pharmaceutical biology.
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Circulation. Arrhythmia and electrophysiology.
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Journal of pharmacy practice.
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Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.
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Nephrology (Carlton, Vic.).
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Hypertension (Dallas, Tex. : 1979).
2017 07; 70(1):94-102. doi:
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Pharmacological reports : PR.
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Journal of molecular modeling.
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The American journal of medicine.
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Histology and histopathology.
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Pakistan journal of pharmaceutical sciences.
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Journal of ethnopharmacology.
2017 Feb; 198(?):432-443. doi:
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The American journal of emergency medicine.
2017 Jan; 35(1):192.e1-192.e2. doi:
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The journal of physiological sciences : JPS.
2017 Jan; 67(1):227-234. doi:
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PloS one.
2017; 12(4):e0176316. doi:
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JAMA internal medicine.
2017 Jan; 177(1):67-76. doi:
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Terapevticheskii arkhiv.
2017 ; 89(12):133-140. doi:
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Journal of the American Society of Hypertension : JASH.
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Clinical journal of the American Society of Nephrology : CJASN.
2016 11; 11(11):1944-1953. doi:
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JAMA internal medicine.
2016 08; 176(8):1085-92. doi:
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BMC health services research.
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American journal of physiology. Renal physiology.
2016 05; 310(10):F1047-53. doi:
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Clinical journal of the American Society of Nephrology : CJASN.
2016 Mar; 11(3):471-80. doi:
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Luminescence : the journal of biological and chemical luminescence.
2016 Mar; 31(2):468-477. doi:
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Drug metabolism and personalized therapy.
2016 Mar; 31(1):47-54. doi:
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Journal of physiology and pharmacology : an official journal of the Polish Physiological Society.
2016 Feb; 67(1):75-91. doi:
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FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
2016 Jan; 30(1):370-9. doi:
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Cardiovascular & hematological agents in medicinal chemistry.
2016; 14(1):49-52. doi:
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Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.
2016 Jan; 31(1):142-9. doi:
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Clinical journal of the American Society of Nephrology : CJASN.
2015 Dec; 10(12):2159-69. doi:
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Chest.
2015 Dec; 148(6):1447-1453. doi:
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Molecular pharmaceutics.
2015 Nov; 12(11):4166-73. doi:
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American journal of kidney diseases : the official journal of the National Kidney Foundation.
2015 Nov; 66(5):783-91. doi:
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Indian journal of pharmacology.
2015 Sep; 47(5):540-5. doi:
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Nature reviews. Nephrology.
2015 Aug; 11(8):447-8. doi:
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American journal of kidney diseases : the official journal of the National Kidney Foundation.
2015 Aug; 66(2):305-12. doi:
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Biochimica et biophysica acta.
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Clinical pharmacology and therapeutics.
2015 Jul; 98(1):25-33. doi:
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Kidney international.
2015 Jun; 87(6):1097-9. doi:
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Clinical journal of the American Society of Nephrology : CJASN.
2015 Apr; 10(4):547-50. doi:
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Clinical journal of the American Society of Nephrology : CJASN.
2015 Apr; 10(4):639-45. doi:
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The New England journal of medicine.
2015 03; 372(10):976. doi:
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The New England journal of medicine.
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The New England journal of medicine.
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The New England journal of medicine.
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Nature reviews. Nephrology.
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Blood purification.
2015; 40(3):232-42. doi:
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Kardiologiia.
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PloS one.
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