Exact Mass: 410.146419
Exact Mass Matches: 410.146419
Found 500 metabolites which its exact mass value is equals to given mass value 410.146419,
within given mass tolerance error 0.05 dalton. Try search metabolite list with more accurate mass tolerance error
0.01 dalton.
Bruceine
Bruceine D is a quassinoid that is 13,20-epoxypicras-3-ene substituted by hydroxy groups at positions 1, 11, 12, 14 and 15 and oxo groups at positions 2 and 16. Isolated from the ethanol extract of the stem of Brucea mollis, it exhibits cytotoxic activity. It has a role as a metabolite, an antineoplastic agent and a plant metabolite. It is a delta-lactone, a pentol, a quassinoid, an organic heteropentacyclic compound and a secondary alpha-hydroxy ketone. It derives from a hydride of a picrasane. Brucein D is a natural product found in Brucea javanica, Brucea mollis, and Samadera indica with data available. A quassinoid that is 13,20-epoxypicras-3-ene substituted by hydroxy groups at positions 1, 11, 12, 14 and 15 and oxo groups at positions 2 and 16. Isolated from the ethanol extract of the stem of Brucea mollis, it exhibits cytotoxic activity. Bruceine D is a Notch inhibitor with anti-cancer activity and induces apoptosis in several human cancer cells. Bruceine D is an effective botanical insect antifeedant with outstanding systemic properties, causing potent pest growth inhibitory activity[1][2]. Bruceine D has strong anthelmintic activity against D. intermedius with an EC50 value of 0.57 mg/L[3]. Bruceine D is a Notch inhibitor with anti-cancer activity and induces apoptosis in several human cancer cells. Bruceine D is an effective botanical insect antifeedant with outstanding systemic properties, causing potent pest growth inhibitory activity[1][2]. Bruceine D has strong anthelmintic activity against D. intermedius with an EC50 value of 0.57 mg/L[3].
Lactupicrin
Lactucopicrin is an azulenofuran, a cyclic terpene ketone, an enone, a member of phenols, a sesquiterpene lactone and a primary alcohol. It has a role as a plant metabolite, a sedative and an antimalarial. It is functionally related to a 4-hydroxyphenylacetic acid and a lactucin. Lactupicrin is a natural product found in Cichorium endivia, Cichorium spinosum, and other organisms with data available. Constituent of Lactuca sativa (lettuce), Cichorium intybus (chicory) and Cichorium endivia (endive). Lactupicrin is found in many foods, some of which are endive, romaine lettuce, chicory, and lettuce. Lactupicrin is found in chicory. Lactupicrin is a constituent of Lactuca sativa (lettuce), Cichorium intybus (chicory) and Cichorium endivia (endive) Lactupicrin (Lactucopicrin) is a characteristic bitter sesquiterpene lactone that can relieve pain. Lactupicrin exhibits atheroprotective effect[1][2]. Lactupicrin (Lactucopicrin) is a characteristic bitter sesquiterpene lactone that can relieve pain. Lactupicrin exhibits atheroprotective effect[1][2].
alpha-Mangostin
Alpha-mangostin is a member of the class of xanthones that is 9H-xanthene substituted by hydroxy group at positions 1, 3 and 6, a methoxy group at position 7, an oxo group at position 9 and prenyl groups at positions 2 and 8. Isolated from the stems of Cratoxylum cochinchinense, it exhibits antioxidant, antimicrobial and antitumour activities. It has a role as an antineoplastic agent, an antimicrobial agent, an antioxidant and a plant metabolite. It is a member of xanthones, a member of phenols and an aromatic ether. Mangostin is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. alpha-Mangostin is a natural product found in Garcinia merguensis, Garcinia cowa, and other organisms with data available. See also: Garcinia mangostana fruit rind (part of). A member of the class of xanthones that is 9H-xanthene substituted by hydroxy group at positions 1, 3 and 6, a methoxy group at position 7, an oxo group at position 9 and prenyl groups at positions 2 and 8. Isolated from the stems of Cratoxylum cochinchinense, it exhibits antioxidant, antimicrobial and antitumour activities. alpha-Mangostin is found in fruits. alpha-Mangostin is a pigment from Garcinia mangostana (mangosteen Pigment from Garcinia mangostana (mangosteen). alpha-Mangostin is found in fruits. alpha-Mangostin (α-Mangostin) is a dietary xanthone with broad biological activities, such as antioxidant, anti-allergic, antiviral, antibacterial, anti-inflammatory and anticancer effects. It is an inhibitor of mutant IDH1 (IDH1-R132H) with a Ki of 2.85 μM. alpha-Mangostin (α-Mangostin) is a dietary xanthone with broad biological activities, such as antioxidant, anti-allergic, antiviral, antibacterial, anti-inflammatory and anticancer effects. It is an inhibitor of mutant IDH1 (IDH1-R132H) with a Ki of 2.85 μM.
Tephrosin
Tephrosin is a member of the class of rotenones that is 13,13a-dihydro-3H-chromeno[3,4-b]pyrano[2,3-h]chromen-7(7aH)-one substituted with geminal methyl groups at position 3, hydroxy group at position 7a and methoxy groups at positions 9 and 10 (the 7aR,13aR stereoisomer). It is isolated from the leaves and twigs of Antheroporum pierrei and exhibits antineoplastic and pesticidal activities. It has a role as a pesticide, an antineoplastic agent and a metabolite. It is an organic heteropentacyclic compound, an aromatic ether, a cyclic ketone and a member of rotenones. Tephrosin is a natural product found in Millettia ferruginea, Tephrosia vogelii, and other organisms with data available. A member of the class of rotenones that is 13,13a-dihydro-3H-chromeno[3,4-b]pyrano[2,3-h]chromen-7(7aH)-one substituted with geminal methyl groups at position 3, hydroxy group at position 7a and methoxy groups at positions 9 and 10 (the 7aR,13aR stereoisomer). It is isolated from the leaves and twigs of Antheroporum pierrei and exhibits antineoplastic and pesticidal activities.
(-)-cis-Rotenolone
(-)-cis-Rotenolone is found in jicama. (-)-cis-Rotenolone is isolated from Pachyrrhizus erosus (yam bean). Isolated from Pachyrrhizus erosus (yam bean). (-)-cis-Rotenolone is found in jicama and pulses.
1-Isomangostin
Constituent of Garcinia mangostana (mangosteen). 1-Isomangostin is found in fruits and purple mangosteen. 1-Isomangostin is found in fruits. 1-Isomangostin is a constituent of Garcinia mangostana (mangosteen)
Sumatrol
Toxicarin
Linrodostat
C308 - Immunotherapeutic Agent > C129820 - Antineoplastic Immunomodulating Agent C308 - Immunotherapeutic Agent > C141144 - Immune Checkpoint Modulator C471 - Enzyme Inhibitor > C141137 - IDO1 Inhibitor D004791 - Enzyme Inhibitors C274 - Antineoplastic Agent
3-Isomangostin
3-Isomangostin is a member of xanthones. 3-Isomangostin is a natural product found in Garcinia morella, Cratoxylum formosum, and other organisms with data available. Constituent of Garcinia mangostana (mangosteen). 3-Isomangostin is found in fruits and purple mangosteen. 3-Isomangostin is found in fruits. 3-Isomangostin is a constituent of Garcinia mangostana (mangosteen). 3-Isomangostin, extracted from Garciniamangostana.L. shell, is a potent MutT homologue 1 (MTH1) inhibitor with an IC50 value of 52?nM. 3-Isomangostin would be an attractive chemical tool for the development of anticancer agents[1]. 3-Isomangostin, extracted from Garciniamangostana.L. shell, is a potent MutT homologue 1 (MTH1) inhibitor with an IC50 value of 52?nM. 3-Isomangostin would be an attractive chemical tool for the development of anticancer agents[1].
Clobetasol
C22H28ClFO4 (410.16600500000004)
Clobetasol is only found in individuals that have used or taken this drug. It is a derivative of prednisolone with high glucocorticoid activity and low mineralocorticoid activity. Absorbed through the skin faster than fluocinonide, it is used topically in treatment of psoriasis but may cause marked adrenocortical suppression. [PubChem]The precise mechanism of the antiinflammatory activity of topical steroids in the treatment of steroid-responsive dermatoses, in general, is uncertain. However, corticosteroids are thought to act by the induction of phospholipase A2 inhibitory proteins, collectively called lipocortins. It is postulated that these proteins control the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes by inhibiting the release of their common precursor arachidonic acid. Arachidonic acid is released from membrane phospholipids by phospholipase A2. Initially, however, clobetasol, like other corticosteroids, bind to the glucocorticoid receptor, which complexes, enteres the cell nucleus and modifies genetic transcription (transrepression/transactivation). D - Dermatologicals > D07 - Corticosteroids, dermatological preparations > D07A - Corticosteroids, plain > D07AD - Corticosteroids, very potent (group iv) D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones > D005938 - Glucocorticoids C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C1636 - Therapeutic Steroid Hormone C308 - Immunotherapeutic Agent > C574 - Immunosuppressant > C211 - Therapeutic Corticosteroid D000893 - Anti-Inflammatory Agents
Dulxanthone B
Dulxanthone B is found in fruits. Dulxanthone B is a constituent of the stem bark of Garcinia dulcis (mundu). Constituent of the stem bark of Garcinia dulcis (mundu). Dulxanthone B is found in fruits.
Butyl 3-O-caffeoylquinate
Butyl 3-O-caffeoylquinate is found in fruits. Butyl 3-O-caffeoylquinate is a constituent of Spondias mombin (yellow mombin) Constituent of Spondias mombin (yellow mombin). Butyl 3-O-caffeoylquinate is found in fruits.
Eremopetasitenin C3
Eremopetasitenin D3 is found in green vegetables. Eremopetasitenin D3 is a constituent of Petasites japonicus (sweet coltsfoot). Constituent of Petasites japonicus (sweet coltsfoot). Eremopetasitenin C3 is found in green vegetables.
(5a,6a,8a,11a)-8-Hydroxy-2-oxo-1(10),3-guaiadien-12,6-olide-15-al 8-(4-hydroxyphenylacetate)
(5a,6a,8a,11a)-8-Hydroxy-2-oxo-1(10),3-guaiadien-12,6-olide-15-al 8-(4-hydroxyphenylacetate) is found in coffee and coffee products. (5a,6a,8a,11a)-8-Hydroxy-2-oxo-1(10),3-guaiadien-12,6-olide-15-al 8-(4-hydroxyphenylacetate) is a constituent of Cichorium intybus (chicory). Constituent of Cichorium intybus (chicory). (5a,6a,8a,11a)-8-Hydroxy-2-oxo-1(10),3-guaiadien-12,6-olide-15-al 8-(4-hydroxyphenylacetate) is found in coffee and coffee products, herbs and spices, and green vegetables.
Clocortolone
C22H28ClFO4 (410.16600500000004)
Clocortolone is only found in individuals that have used or taken this drug. It is a medium potency corticosteroid that is often used as a topical cream for the relief of inflammatory oand pruritic (itching) arising from steroid-responsive dermatoses of the scalp.The precise mechanism of the antiinflammatory activity of topical steroids in the treatment of steroid-responsive dermatoses, in general, is uncertain. However, corticosteroids are thought to act by the induction of phospholipase A2 inhibitory proteins, collectively called lipocortins. It is postulated that these proteins control the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes by inhibiting the release of their common precursor arachidonic acid. Arachidonic acid is released from membrane phospholipids by phospholipase A2. These enzyme transcriptional changes are mediated by the drug binding first to the glucocorticoid receptor. This complex can migrate to the cell nucleus which then binds to DNA initiating genetic activation and repression of various genes. D - Dermatologicals > D07 - Corticosteroids, dermatological preparations > D07A - Corticosteroids, plain > D07AB - Corticosteroids, moderately potent (group ii) D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones > D005938 - Glucocorticoids C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C1636 - Therapeutic Steroid Hormone C308 - Immunotherapeutic Agent > C574 - Immunosuppressant > C211 - Therapeutic Corticosteroid D000893 - Anti-Inflammatory Agents
Tipredane
C22H31FO2S2 (410.17493979999995)
Tipredane belongs to the family of Sesterterpenes. These are terpenes compsed of five consecutive isoprene units.
Buparlisib
C274 - Antineoplastic Agent > C163758 - Targeted Therapy Agent > C2152 - Phosphatidylinositide 3-Kinase Inhibitor C274 - Antineoplastic Agent > C2189 - Signal Transduction Inhibitor > C129824 - Antineoplastic Protein Inhibitor C471 - Enzyme Inhibitor > C129825 - Antineoplastic Enzyme Inhibitor C274 - Antineoplastic Agent > C1742 - Angiogenesis Inhibitor C471 - Enzyme Inhibitor > C1404 - Protein Kinase Inhibitor
Bruceine D
Deoxycorticosterone sulfate
Epicocconone
Eurycomanol
Lemborexant
Phenobarbital N-glucoside
C18H22N2O9 (410.13252420000003)
1,3,6-Trihydroxy-7-methoxy-2,5-bis(3-methyl-2-butenyl)xanthone
Aloenin
Aloenin is a glycoside. Aloenin is a natural product found in Aloe africana, Aloe nyeriensis, and other organisms with data available. See also: Aloe Vera Leaf (part of). Aloenin (Aloenin A) is a natural compound, which has potent peroxyl radical-scavenging activities and moderate inhibitory active on β-secretase (BACE)[1][2]. Aloenin (Aloenin A) is a natural compound, which has potent peroxyl radical-scavenging activities and moderate inhibitory active on β-secretase (BACE)[1][2].
Pasakbumin C
13,21-Dihydroeurycomanone, a natural compound isolated from Eurycoma longifolia root, possesses anti-parasite activity for Plasmodium falciparum and Toxoplasma gondii[1][2].
CRATOXYARBORENONE D
An organic heterotetracyclic compound that is 2,3-dihydro-5H-furo[3,2-b]xanthen-5-one substituted by hydroxy groups at positions 4, 7, 8 and 9, an isoprenyl group at position 6 and a prop-1-en-2-yl group at position 2. It is isolated from Cratoxylum Sumatranum and exhibits cytotoxicity towards the KB (human oral epidermoid) cancer cell line.
Amorphispironone
Cochinchinone C
A polycyclic cage that is a prenylated-caged xanthone isolated from Cratoxylum cochinchinense and has been shown to exhibit antimalarial and antioxidant activities.
Velloquercetin 3,5,3-trimethyl ether
brasixanthone C
A member of the class of pyranoxanthones that is 2H,6H-pyrano[3,2-b]xanthen-6-one substituted by a 2-hydroperoxy-3-methylbut-3-en-1-yl moiety at position 12, hydroxy groups at positions 5 and 8 and geminal methyl groups at position 2. It is isolated from the stem bark of Calophyllum brasiliense and exhibits significant inhibitory activity against 12-O-tetradecanoylphorbol-13-acetate induced Epstein-Barr virus early antigen activation in Raji cells.
8beta-Propionyloxy-10beta-hydroxyhirsutinolide-13-O-acetate
Rubraxanthone
A member of the class of xanthones that is 9H-xanthen-9-one substituted by hydroxy groups at positions 3, 6 and 8, a geranyl group at position 1 and a methoxy group at position 2. Isolated from Mesua and Garcinia dioica, it exhibits antibacterial and cytotoxic activities.
paxanthonin
A member of the class of xanthones that is 9H-xanthen-9-one substituted by a 2,2-dimethyl-4-(prop-1-en-2-yl)cyclopentyl group at position 2, hydroxy groups at positions 1, 3 and 6 and a methoxy group at position 5. It is isolated from the callus of Hypericum perforatum and exhibits antioxidant and antimicrobial activities.
Toxicarolisoflavone
Toxicarolisoflavone is a natural product found in Derris montana, Derris ovalifolia, and other organisms with data available.
Amorphigenin
Origin: Plant, Pyrans relative retention time with respect to 9-anthracene Carboxylic Acid is 1.086 relative retention time with respect to 9-anthracene Carboxylic Acid is 1.088
Pongapinone A
Pirlimycin
C17H31ClN2O5S (410.16421060000005)
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D055231 - Lincosamides C784 - Protein Synthesis Inhibitor > C82922 - Lincosamide Antibiotic C254 - Anti-Infective Agent > C258 - Antibiotic
Cratoxyarborenone E
A member of the class of xanthones that is 9H-xanthen-9-one substituted by hydroxy groups at positions 1, 3 and 7, isoprenyl groups at positions 4 and 5 and a methoxy group at position 6. It is isolated from Cratoxylum Sumatranum and exhibits cytotoxicity towards the KB (human oral epidermoid) cancer cell line.
11-hydroxy-13-chloro-11,13-dihydroatripliciolide-8-O-tiglate
13-Hydroxy-5-methoxy-3,3,10,10-tetramethyl-2,3,11,12-tetrahydro-1H,10H-dipyrano[3,2-a;2,3-i]xanthen-14-on|13-hydroxy-5-methoxy-3,3,10,10-tetramethyl-2,3,11,12-tetrahydro-1H,10H-dipyrano[3,2-a;2,3-i]xanthen-14-one|BR-xanthone A monomethyl ether|Tovophyllin A
8-C-glucosyl-7-O-methyl-(S)-aloesol|8-C-glycosyl-7-O-methyl-(R)-aloesol
1,3,6-trihydroxy-7-methoxy-2-(3,7-dimethyl-2,6-octadienyl)xanthone
(-)-2beta-(2xi,3-epoxy-3-methyl-1-oxobutyl)-2-deoxybruceol
(1R*,4R*,8S*,10R*)-1,4-epoxy-1-methoxy-8-hydroxy-10,13-diacetoxygermacra-5E,7(11)-dien-6,12-olide
2-Methylbutanoic acid 3-[1-(1,3-benzodioxole-5-yl)-1,2-epoxy-6-methoxy-1,2-dihydrobenzocyclobutene-4-yl]propyl ester
rakanmakilactone C|rakanmakilactone D
C20H26O7S (410.13991660000005)
8-Propanoyl,13-Ac-1,4-Epoxy-1,8,10,13-tetrahydroxy-5,7(11)-germacradien-12,6-olide
1,5-dihydroxy-8-methoxy-7-(3,3-dimethyl-20-propenyl)-4,4,5-trimethylfurano-[2,3:4,3]-xanthone|inophinnin
3-methoxycheffouxanthone|4-(3,7-dimethyl-2,6-octadienyl)-1,5,8-trihydroxy-3-methoxyxanthone
3-hydroxy-6-methoxy-5-isopropyl-4,5-dihydrofuro[2,3:7,8]-6,6-dimethyl-4,5-dihydropyrano[2,3:1,2]xanthone
1,6-dihydroxy-7-methoxy-8-(3-methylbut-3-enyl)-6,6-dimethyl-4,5-dihydropyrano[23:3,2]xanthone
1-(4-Hydroxy-3-methoxyphenyl)-2-[4-(1,2,3-trihydroxypropyl)-2-methoxyphenoxy]-1,3-propanediol
1,7-dihydroxy-8-methoxy-6-(3-methyl-2-butenyl)-4,4-dimethylfurano-[2,3:3,4]-xanthone|mesuaferrin C
butyl 4-O-caffeoylquinate|butyl chryptochlorogenate|n-butyl 4-trans-O-caffeoylquinate
2,3-dihydro-7-hydroxy-2S*,3R*-dimethyl-2-[4-methyl-5-(4-methyl-5-oxo-2,5-dihydro-2-furyl)-3(E)-pentenyl]furo[3,2-c]coumarin|fukanefuromarin J
1-O-hexanoyl-6-O-beta-D-xylopyranosyl-beta-D-glucopyranose|nonioside S
(6aS*,9R*,9aS*)-6a-methyl-9-(2-methylbutyryl)-3-[(1S*,6S*)-6-methyl-2-oxocyclohex-3-enyl]-9,9a-dihydro-6aH-furo[2,3-h]isochromene-6,8-dione|multiformin A
8alpha-(4-hydroxymethacryloyloxy)-10alpha-hydroxy-13-methoxy-hirsutinolide
10-cinnamoyloxy-6-methoxy-8,9-epoxythymol isobutyrate
beta-Hydroxy-beta-methylglutarylhydroxy-abscisicsaeure; HMG-HO ABA
6-O-(2-methylbutyryl-beta-D-glucopyranoside)-1-O-E-p-coumarate
(6S*,9aS*)-5,6-dihydro-3-[(1Z,4E,6E,8E)-1-hydroxy-3-oxo-1,4,6,8-decatetraenyl]-6-hydroxymethyl-9a-methyl-2H-furo[3,2-g]benzopyran-2-9(9H)-dione|epicocconone
3,3,12,12-Tetramethyl-5-hydroxy-9-methoxy-1,2,3,10,11,12,14-heptahydro-4,7,13-trioxadibenzo[a,j]anthracene-14-one
1,3,5-trihydroxy-6-methoxy-2-(1,1-dimethyl-2-propenyl)-7-(3-methyl-2-butenyl)-9H-xanthen-9-one|Cudrafrutixanthone|cudrafrutixanthone A
3-((3R)-butoxy-(2R)-caffeoyl-(1R)-hydroxycyclobutyl)-(3R)-hydroxypropanoic acid|dorycnic acid
1,3,6-Trihydroxy-2,7-bis(3-methyl-2-butenyl)-5-methoxyxanthone
4alpha-(2,4-dihydroxy-3-methoxyphenyl)-(-)-fisetinidol
3,4,8-Tri-Me ether-5,10-Dihydroxy-8-(3,4-dihydroxyphenyl)-2,2-dimethyl-2H,6H-benzo[1,2-b:5,4-b]dipyran-6-one
1,4,6-trihydroxy-3-methoxy-2-(3-methyl-2-butenyl)-5-(1,1-dimethyl-prop-2-enyl)xanthone
1-O-(3-methylbut-3-en-1-yl)-6-O-beta-D-glucopyranosyl-beta-D-glucopyranose|3-methyl-3-butenyl 6-O-beta-D-glucopyranosyl-beta-D-glucopyranoside|3-methylbut-3-enyl 6-O-beta-D-glucopyranosyl-beta-D-glucopyranoside|3-methylbut-3-enyl-6-O-beta-D-glucopyranosyl-beta-D-glucopyranose|3-methylbut-3-enyl6-O-beta-D-glucopyranosyl-beta-D-glucopyranoside|nonioside A
2,2-Dimethyl-5,8-dihydroxy-12-[hydroxy(3,3-dimethyloxiranyl)methyl]-2H,6H-pyrano[3,2-b]xanthene-6-one
(Rac)-Tephrosin
(1R,14R)-14-Hydroxy-17,18-dimethoxy-7,7-dimethyl-2,8,21-trioxapentacyclo[12.8.0.0^{3,12.0^{4,9.0^{15,20]docosa-3(12),4(9),5,10,15,17,19-heptaen-13-one is a member of rotenones. (1R,14R)-14-hydroxy-17,18-dimethoxy-7,7-dimethyl-2,8,21-trioxapentacyclo[12.8.0.0^{3,12.0^{4,9.0^{15,20]docosa-3(12),4(9),5,10,15,17,19-heptaen-13-one is a natural product found in Millettia ferruginea, Derris trifoliata, and other organisms with data available.
Yadanziolide C
Yadanziolide C is a natural product found in Brucea javanica and Brucea mollis with data available.
13,21-Dihydroeurycomanone
13,21-Dihydroeurycomanone is a natural product found in Eurycoma longifolia with data available. 13,21-Dihydroeurycomanone, a natural compound isolated from Eurycoma longifolia root, possesses anti-parasite activity for Plasmodium falciparum and Toxoplasma gondii[1][2].
Mangostin
relative retention time with respect to 9-anthracene Carboxylic Acid is 1.514 relative retention time with respect to 9-anthracene Carboxylic Acid is 1.515 alpha-Mangostin (α-Mangostin) is a dietary xanthone with broad biological activities, such as antioxidant, anti-allergic, antiviral, antibacterial, anti-inflammatory and anticancer effects. It is an inhibitor of mutant IDH1 (IDH1-R132H) with a Ki of 2.85 μM. alpha-Mangostin (α-Mangostin) is a dietary xanthone with broad biological activities, such as antioxidant, anti-allergic, antiviral, antibacterial, anti-inflammatory and anticancer effects. It is an inhibitor of mutant IDH1 (IDH1-R132H) with a Ki of 2.85 μM.
Pergolide mesylate
D018377 - Neurotransmitter Agents > D015259 - Dopamine Agents > D018491 - Dopamine Agonists C78272 - Agent Affecting Nervous System > C38149 - Antiparkinsonian Agent C78272 - Agent Affecting Nervous System > C66884 - Dopamine Agonist Pergolide mesylate (Pergolide methanesulfonate), an Ergoline derivative, is a potent and orally active dopamine D1 and D2 receptors agonist. Pergolide mesylate can be used for Parkinson's disease and hyperprolactinaemia research[1][2].
6-[4-hydroxy-2-methyl-6-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]-4-methoxypyran-2-one
1,3,7-trihydroxy-6-methoxy-4,5-bis(3-methylbut-2-enyl)xanthen-9-one
2-(hydroxymethyl)-5-(2-oxopropyl)-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one
(2s,6as,12as)-6a-hydroxy-8,9-dimethoxy-2-(prop-1-en-2-yl)-1,2,12,12a-tetrahydrochromeno[3,4-b]furo[2,3-h]chromen-6(6ah)-one
Clobetasol
C22H28ClFO4 (410.16600500000004)
D - Dermatologicals > D07 - Corticosteroids, dermatological preparations > D07A - Corticosteroids, plain > D07AD - Corticosteroids, very potent (group iv) D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones > D005938 - Glucocorticoids C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C1636 - Therapeutic Steroid Hormone C308 - Immunotherapeutic Agent > C574 - Immunosuppressant > C211 - Therapeutic Corticosteroid D000893 - Anti-Inflammatory Agents CONFIDENCE standard compound; INTERNAL_ID 2399
Lactucopicrin
Lactupicrin (Lactucopicrin) is a characteristic bitter sesquiterpene lactone that can relieve pain. Lactupicrin exhibits atheroprotective effect[1][2]. Lactupicrin (Lactucopicrin) is a characteristic bitter sesquiterpene lactone that can relieve pain. Lactupicrin exhibits atheroprotective effect[1][2].
Ala Ala Cys Phe
C18H26N4O5S (410.16238260000006)
Ala Ala Phe Cys
C18H26N4O5S (410.16238260000006)
Ala Cys Ala Phe
C18H26N4O5S (410.16238260000006)
Ala Cys Phe Ala
C18H26N4O5S (410.16238260000006)
Ala Cys Met Ser
C14H26N4O6S2 (410.12936959999996)
Ala Cys Ser Met
C14H26N4O6S2 (410.12936959999996)
Ala Phe Ala Cys
C18H26N4O5S (410.16238260000006)
Ala Phe Cys Ala
C18H26N4O5S (410.16238260000006)
Ala Met Cys Ser
C14H26N4O6S2 (410.12936959999996)
Ala Met Ser Cys
C14H26N4O6S2 (410.12936959999996)
Ala Ser Cys Met
C14H26N4O6S2 (410.12936959999996)
Ala Ser Met Cys
C14H26N4O6S2 (410.12936959999996)
Cys Ala Ala Phe
C18H26N4O5S (410.16238260000006)
Cys Ala Phe Ala
C18H26N4O5S (410.16238260000006)
Cys Ala Met Ser
C14H26N4O6S2 (410.12936959999996)
Cys Ala Ser Met
C14H26N4O6S2 (410.12936959999996)
Cys Cys Ser Val
C14H26N4O6S2 (410.12936959999996)
Cys Cys Val Ser
C14H26N4O6S2 (410.12936959999996)
Cys Phe Ala Ala
C18H26N4O5S (410.16238260000006)
Cys Gly Met Thr
C14H26N4O6S2 (410.12936959999996)
Cys Gly Thr Met
C14H26N4O6S2 (410.12936959999996)
Cys Met Ala Ser
C14H26N4O6S2 (410.12936959999996)
Cys Met Gly Thr
C14H26N4O6S2 (410.12936959999996)
Cys Met Ser Ala
C14H26N4O6S2 (410.12936959999996)
Cys Met Thr Gly
C14H26N4O6S2 (410.12936959999996)
Cys Ser Ala Met
C14H26N4O6S2 (410.12936959999996)
Cys Ser Cys Val
C14H26N4O6S2 (410.12936959999996)
Cys Ser Met Ala
C14H26N4O6S2 (410.12936959999996)
Cys Ser Thr Thr
C14H26N4O8S (410.14712760000003)
Cys Ser Val Cys
C14H26N4O6S2 (410.12936959999996)
Cys Thr Gly Met
C14H26N4O6S2 (410.12936959999996)
Cys Thr Met Gly
C14H26N4O6S2 (410.12936959999996)
Cys Thr Ser Thr
C14H26N4O8S (410.14712760000003)
Cys Thr Thr Ser
C14H26N4O8S (410.14712760000003)
Cys Val Cys Ser
C14H26N4O6S2 (410.12936959999996)
Cys Val Ser Cys
C14H26N4O6S2 (410.12936959999996)
Asp Gly Gly Tyr
Asp Gly Tyr Gly
Asp Tyr Gly Gly
Phe Ala Ala Cys
C18H26N4O5S (410.16238260000006)
Phe Ala Cys Ala
C18H26N4O5S (410.16238260000006)
Phe Cys Ala Ala
C18H26N4O5S (410.16238260000006)
Phe Gly Gly Met
C18H26N4O5S (410.16238260000006)
Phe Gly Met Gly
C18H26N4O5S (410.16238260000006)
Phe Met Gly Gly
C18H26N4O5S (410.16238260000006)
Gly Cys Met Thr
C14H26N4O6S2 (410.12936959999996)
Gly Cys Thr Met
C14H26N4O6S2 (410.12936959999996)
Gly Asp Gly Tyr
Gly Asp Tyr Gly
Gly Phe Gly Met
C18H26N4O5S (410.16238260000006)
Gly Phe Met Gly
C18H26N4O5S (410.16238260000006)
Gly Gly Asp Tyr
Gly Gly Phe Met
C18H26N4O5S (410.16238260000006)
Gly Gly Met Phe
C18H26N4O5S (410.16238260000006)
Gly Gly Tyr Asp
Gly Met Cys Thr
C14H26N4O6S2 (410.12936959999996)
Gly Met Phe Gly
C18H26N4O5S (410.16238260000006)
Gly Met Gly Phe
C18H26N4O5S (410.16238260000006)
Gly Met Thr Cys
C14H26N4O6S2 (410.12936959999996)
Gly Thr Cys Met
C14H26N4O6S2 (410.12936959999996)
Gly Thr Met Cys
C14H26N4O6S2 (410.12936959999996)
Gly Tyr Asp Gly
Gly Tyr Gly Asp
Met Ala Cys Ser
C14H26N4O6S2 (410.12936959999996)
Met Ala Ser Cys
C14H26N4O6S2 (410.12936959999996)
Met Cys Ala Ser
C14H26N4O6S2 (410.12936959999996)
Met Cys Gly Thr
C14H26N4O6S2 (410.12936959999996)
Met Cys Ser Ala
C14H26N4O6S2 (410.12936959999996)
Met Cys Thr Gly
C14H26N4O6S2 (410.12936959999996)
Met Phe Gly Gly
C18H26N4O5S (410.16238260000006)
Met Gly Cys Thr
C14H26N4O6S2 (410.12936959999996)
Met Gly Phe Gly
C18H26N4O5S (410.16238260000006)
Met Gly Gly Phe
C18H26N4O5S (410.16238260000006)
Met Gly Thr Cys
C14H26N4O6S2 (410.12936959999996)
Met Ser Ala Cys
C14H26N4O6S2 (410.12936959999996)
Met Ser Cys Ala
C14H26N4O6S2 (410.12936959999996)
Met Ser Ser Ser
C14H26N4O8S (410.14712760000003)
Met Thr Cys Gly
C14H26N4O6S2 (410.12936959999996)
Met Thr Gly Cys
C14H26N4O6S2 (410.12936959999996)
Ser Ala Cys Met
C14H26N4O6S2 (410.12936959999996)
Ser Ala Met Cys
C14H26N4O6S2 (410.12936959999996)
Ser Cys Ala Met
C14H26N4O6S2 (410.12936959999996)
Ser Cys Cys Val
C14H26N4O6S2 (410.12936959999996)
Ser Cys Met Ala
C14H26N4O6S2 (410.12936959999996)
Ser Cys Thr Thr
C14H26N4O8S (410.14712760000003)
Ser Cys Val Cys
C14H26N4O6S2 (410.12936959999996)
Ser Met Ala Cys
C14H26N4O6S2 (410.12936959999996)
Ser Met Cys Ala
C14H26N4O6S2 (410.12936959999996)
Ser Met Ser Ser
C14H26N4O8S (410.14712760000003)
Ser Ser Met Ser
C14H26N4O8S (410.14712760000003)
Ser Ser Ser Met
C14H26N4O8S (410.14712760000003)
Ser Thr Cys Thr
C14H26N4O8S (410.14712760000003)
Ser Thr Thr Cys
C14H26N4O8S (410.14712760000003)
Ser Val Cys Cys
C14H26N4O6S2 (410.12936959999996)
Thr Cys Gly Met
C14H26N4O6S2 (410.12936959999996)
Thr Cys Met Gly
C14H26N4O6S2 (410.12936959999996)
Thr Cys Ser Thr
C14H26N4O8S (410.14712760000003)
Thr Cys Thr Ser
C14H26N4O8S (410.14712760000003)
Thr Gly Cys Met
C14H26N4O6S2 (410.12936959999996)
Thr Gly Met Cys
C14H26N4O6S2 (410.12936959999996)
Thr Met Cys Gly
C14H26N4O6S2 (410.12936959999996)
Thr Met Gly Cys
C14H26N4O6S2 (410.12936959999996)
2H-Indol-2-one, 1,3-dihydro-7-hydroxy-4-[2-(propylamino)ethyl]- glucuronide
Thr Ser Cys Thr
C14H26N4O8S (410.14712760000003)
Thr Ser Thr Cys
C14H26N4O8S (410.14712760000003)
Thr Thr Cys Ser
C14H26N4O8S (410.14712760000003)
Thr Thr Ser Cys
C14H26N4O8S (410.14712760000003)
Val Cys Cys Ser
C14H26N4O6S2 (410.12936959999996)
Val Cys Ser Cys
C14H26N4O6S2 (410.12936959999996)
Val Ser Cys Cys
C14H26N4O6S2 (410.12936959999996)
Tyr Asp Gly Gly
Tyr Gly Asp Gly
Tyr Gly Gly Asp
Eremopetasitenin C3
Butyl 3-O-caffeoylquinate
(5a,6a,8a,11a)-8-Hydroxy-2-oxo-1(10),3-guaiadien-12,6-olide-15-al 8-(4-hydroxyphenylacetate)
3-Isomangostin
3-Isomangostin, extracted from Garciniamangostana.L. shell, is a potent MutT homologue 1 (MTH1) inhibitor with an IC50 value of 52?nM. 3-Isomangostin would be an attractive chemical tool for the development of anticancer agents[1]. 3-Isomangostin, extracted from Garciniamangostana.L. shell, is a potent MutT homologue 1 (MTH1) inhibitor with an IC50 value of 52?nM. 3-Isomangostin would be an attractive chemical tool for the development of anticancer agents[1].
Tipredane
C22H31FO2S2 (410.17493979999995)
C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C1636 - Therapeutic Steroid Hormone C308 - Immunotherapeutic Agent > C574 - Immunosuppressant > C211 - Therapeutic Corticosteroid
2,5-Diphenyl-3-(p-diphenyl)tetrazolium chloride
C25H19ClN4 (410.12981640000004)
butane-1,4-diol,1,3-diisocyanato-2-methylbenzene,hexanedioic acid
Phenol, 2,6-dimethyl-,phosphate (3:1)
C24H27O4P (410.16468720000006)
Pyrimido[2,1-f]purine-2,4,8(1H,3H,9H)-trione,7-[(dimethylamino)methylene]-6,7-dihydro-6-hydroxy-1,3-dimethyl-9-(phenylmethyl)- (9CI)
Darusentan
C78274 - Agent Affecting Cardiovascular System > C270 - Antihypertensive Agent D065128 - Endothelin Receptor Antagonists C28313 - Endothelin Receptor Antagonist Darusentan (Lu-135252) is a selective endothelin receptor A (ET-A) receptor antagonist, which binds with a Ki of 1.4 nM to the ET-A receptor and a Ki of 184 nM to ET-B receptor, respectively with a 100-fold selectivity for ETA rather than ETB receptors[1]. Darusentan competes for radiolabeled endothelin binding in rat aortic vascular smooth muscle cells (RAVSMs) membranes with single-site kinetics, exhibiting a Ki of 13 nM[2].
1-N,4-N-bis(4-methoxyphenyl)-3,6-dimethyl-1,2,4,5-tetrazine-1,4-dicarboxamide
1H-Indazole-1-propanamide,N-[2-(cyclopentylamino)-2-oxoethyl]-N-(2-thienylmethyl)-(9CI)
Phosphonic acid, [[1-[[(methylsulfonyl)oxy]methyl]-2-(phenylmethoxy)ethoxy]methyl]-, diethyl ester-R
C16H27O8PS (410.11641920000005)
2-[2-[4-[(4-chlorophenyl)phenylmethyl]piperazin-1-yl]ethoxy]ethanol hydrochloride
1-N,4-N-bis(2-methoxyphenyl)-3,6-dimethyl-1,2,4,5-tetrazine-1,4-dicarboxamide
1-N,4-N-bis(3-methoxyphenyl)-3,6-dimethyl-1,2,4,5-tetrazine-1,4-dicarboxamide
lemborexant
D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants > D006993 - Hypnotics and Sedatives C78272 - Agent Affecting Nervous System > C142786 - Orexin Receptor Antagonist D018377 - Neurotransmitter Agents > D000068796 - Orexin Receptor Antagonists N - Nervous system > N05 - Psycholeptics > N05C - Hypnotics and sedatives
2-(((3aR,4S,6R,6aS)-6-(7-aMino-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyriMidin-3-yl)-2,2-diMethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethanol
C17H26N6O4S (410.17361560000006)
2-Propenoic acid, 2-Methyl-, [1,1-biphenyl]-4,4-diylbis(oxy-2,1-ethanediyl) ester (9CI)
4-butyl-1,2-diphenylpyrazolidine-3,5-dione, compound with 4,5-dihydrothiazol-2-amine (1:1)
TRANS-4-(4-(DIMETHYLAMINO)STYRYL)-1-ME-&
C23H26N2O3S (410.1664046000001)
2,8-Diazaspiro[4.5]decane, 2-(1-methylethyl)-, 2,2,2-trifluoroacetate (1:2)
C15H24F6N2O4 (410.16401759999997)
Solabegron
C78272 - Agent Affecting Nervous System > C29747 - Adrenergic Agent > C87053 - Adrenergic Agonist D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents > D000322 - Adrenergic Agonists Solabegron (GW 427353) is a selective β3-adrenergic receptor agonist, stimulating cAMP accumulation in Chinese hamster ovary cells expressing the human β3-AR, with an EC50 value of 22 nM[1]. Solabegron (GW 427353) is being developed for the treatment of overactive bladder and irritable bowel syndrome[1].
{(2s)-1-[n-(Tert-Butoxycarbonyl)glycyl]pyrrolidin-2-Yl}methyl (3-Chlorophenyl)acetate
C20H27ClN2O5 (410.16084020000005)
Epicocconone
D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents > D049408 - Luminescent Agents D004396 - Coloring Agents > D005456 - Fluorescent Dyes
Carmoxirole hydrochloride
Carmoxirole hydrochloride (EMD 45609 hydrochloride) is a selective, peripherally acting dopamine D2 receptor agonist and exhibits antihypertensive activities in vivo[1].
6-(2,5-dimethoxyphenyl)-3-(3-propan-2-yloxyphenyl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine
C21H22N4O3S (410.14125420000005)
3-(4-fluorophenyl)-4,4,6,8-tetramethyl-5,6-dihydro-4H,4H-spiro[pyrrolo[3,2,1-ij]quinoline-1,2-[1,3]thiazolidine]-2,4-dione
N-[4-(1H-benzimidazol-2-yl)phenyl]-3-(2,5-dioxo-1-pyrrolidinyl)benzamide
C24H18N4O3 (410.13788379999994)
(1)Benzopyrano(3,4-b)furo(2,3-h)(1)benzopyran-6(6aH)-one,1,2,12,12a-tetrahydro-6a-hydroxy-8,9-dimethoxy-2-(1-methylethenyl)-, (2S-(2alpha,6aalpha,12aalpha))-
1-(4-methylbenzenesulfonyl)-4-(5-phenyl-1H-pyrazole-3-carbonyl)piperazine
C21H22N4O3S (410.14125420000005)
Buparlisib
C274 - Antineoplastic Agent > C163758 - Targeted Therapy Agent > C2152 - Phosphatidylinositide 3-Kinase Inhibitor C274 - Antineoplastic Agent > C2189 - Signal Transduction Inhibitor > C129824 - Antineoplastic Protein Inhibitor C471 - Enzyme Inhibitor > C129825 - Antineoplastic Enzyme Inhibitor C274 - Antineoplastic Agent > C1742 - Angiogenesis Inhibitor C471 - Enzyme Inhibitor > C1404 - Protein Kinase Inhibitor
clocortolone
C22H28ClFO4 (410.16600500000004)
D - Dermatologicals > D07 - Corticosteroids, dermatological preparations > D07A - Corticosteroids, plain > D07AB - Corticosteroids, moderately potent (group ii) D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones > D005938 - Glucocorticoids C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C1636 - Therapeutic Steroid Hormone C308 - Immunotherapeutic Agent > C574 - Immunosuppressant > C211 - Therapeutic Corticosteroid D000893 - Anti-Inflammatory Agents
Diclofenac Epolamine
C78272 - Agent Affecting Nervous System > C241 - Analgesic Agent > C2198 - Nonnarcotic Analgesic D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents D002491 - Central Nervous System Agents > D000700 - Analgesics D000893 - Anti-Inflammatory Agents D018501 - Antirheumatic Agents
4-[[[3-(6-Methoxypyridin-3-yl)imidazo[1,2-b]pyridazin-6-yl]amino]methyl]benzenesulfonamide
Methyl 7-chloro-6,7,8-trideoxy-6-[[[(2S,4R)-4beta-propyl-2alpha-pyrrolidinyl]carbonyl]amino]-1-thio-L-threo-alpha-D-galacto-octopyranoside
C17H31ClN2O5S (410.16421060000005)
14-Hydroxy-17,18-dimethoxy-6,6-dimethyl-2,8,21-trioxahexacyclo[12.8.0.03,12.04,9.05,7.015,20]docosa-3(12),4(9),10,15,17,19-hexaen-13-one
1,3,6-Trihydroxy-7-methoxy-2,5-bis(3-methyl-2-butenyl)xanthone
(1S,2S,3S,4S,5R,6S,8R,9R,12S)-5,6,12-trihydroxy-4-methyl-13-methylidenetetracyclo[10.2.1.01,9.03,8]pentadecane-2,4,8-tricarboxylic acid
[2-amino-7-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl]methyl-[(4S,5R)-4,5-dihydroxycyclopent-2-en-1-yl]azanium
5-Ethyl-5-phenyl-1-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-1,3-diazinane-2,4,6-trione
C18H22N2O9 (410.13252420000003)
6-(hydroxymethyl)-3-[(1Z,4E,6E,8E)-1-hydroxy-3-oxodeca-1,4,6,8-tetraenyl]-9a-methyl-5,6-dihydrofuro[3,2-g]isochromene-2,9-dione
(2S)-2-[12-ethyl-2-hydroxy-8-(hydroxymethyl)-9-oxo-11H-indolizino[1,2-b]quinolin-7-yl]-2-hydroxybutanoic acid
1-(2-Hydroxyethyl)pyrrolidinium {2-[(2,6-dichlorophenyl)amino]phenyl}acetate
D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents D002491 - Central Nervous System Agents > D000700 - Analgesics D000893 - Anti-Inflammatory Agents D018501 - Antirheumatic Agents
Egonol-2-methyl butanoate
A fatty acid ester obtained by the formal condensation of (S)-2-methylbutyric acid with egonol. It has been isolated from the fruits of Styrax agrestis.
(+)-(3R,5S)-fluvastatin
C - Cardiovascular system > C10 - Lipid modifying agents > C10A - Lipid modifying agents, plain > C10AA - Hmg coa reductase inhibitors
N-[4-(4-morpholinyl)phenyl]-2-pyridin-4-yl-4-quinolinecarboxamide
[2-[3-phenyl-2-[(E)-3-phenylprop-2-enoyl]-3,4-dihydropyrazol-5-yl]phenyl] acetate
C26H22N2O3 (410.16303419999997)
N-[1-(3-fluorophenyl)-6,6-dimethyl-5,7-dihydro-4H-indazol-4-yl]-2-(2-pyridinylthio)acetamide
N-[3-(dimethylamino)propyl]-N-(6-methyl-1,3-benzothiazol-2-yl)-1,3-benzothiazole-6-carboxamide
N-[3-(4-methyl-1-piperidinyl)-1,4-dioxo-2-naphthalenyl]benzenesulfonamide
C22H22N2O4S (410.13002120000004)
N-{2-[(2E)-2-(3,4-dimethoxybenzylidene)hydrazinyl]-4-(4-methylphenyl)-1,3-thiazol-5-yl}acetamide
C21H22N4O3S (410.14125420000005)
N-(2,4-dimethoxyphenyl)-3-(6-methyl-1H-benzimidazol-2-yl)-1-piperidinecarbothioamide
3-(3-ethoxypropyl)-1-[(4-oxo-1H-quinazolin-2-yl)methyl]-1-(phenylmethyl)thiourea
6-[3-(cyclopropylmethoxy)-4-methoxyphenyl]-3-(2-fluorophenyl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine
N-benzyl-N-[(2-indol-2-ylidene-3H-1,3,4-thiadiazol-5-yl)methyl]-1-phenylmethanamine
3,4-dihydro-1H-isoquinolin-2-yl-[4-[hydroxy(diphenyl)methyl]-1-triazolyl]methanone
2-[(1R,3R,4aS,9aR)-1-(hydroxymethyl)-6-(methanesulfonamido)-3,4,4a,9a-tetrahydro-1H-pyrano[3,4-b]benzofuran-3-yl]-N-(cyclopropylmethyl)acetamide
C19H26N2O6S (410.15114960000005)
2-[(1R,3R,4aR,9aS)-1-(hydroxymethyl)-6-(methanesulfonamido)-3,4,4a,9a-tetrahydro-1H-pyrano[3,4-b]benzofuran-3-yl]-N-(cyclopropylmethyl)acetamide
C19H26N2O6S (410.15114960000005)
2-[(1R,3S,4aR,9aS)-1-(hydroxymethyl)-6-(methanesulfonamido)-3,4,4a,9a-tetrahydro-1H-pyrano[3,4-b]benzofuran-3-yl]-N-(cyclopropylmethyl)acetamide
C19H26N2O6S (410.15114960000005)
2-[(1R,3S,4aS,9aR)-1-(hydroxymethyl)-6-(methanesulfonamido)-3,4,4a,9a-tetrahydro-1H-pyrano[3,4-b]benzofuran-3-yl]-N-(cyclopropylmethyl)acetamide
C19H26N2O6S (410.15114960000005)
2-[(1S,3R,4aR,9aS)-1-(hydroxymethyl)-6-(methanesulfonamido)-3,4,4a,9a-tetrahydro-1H-pyrano[3,4-b]benzofuran-3-yl]-N-(cyclopropylmethyl)acetamide
C19H26N2O6S (410.15114960000005)
2-[(1S,3S,4aS,9aR)-1-(hydroxymethyl)-6-(methanesulfonamido)-3,4,4a,9a-tetrahydro-1H-pyrano[3,4-b]benzofuran-3-yl]-N-(cyclopropylmethyl)acetamide
C19H26N2O6S (410.15114960000005)
2-[(1S,3S,4aR,9aS)-1-(hydroxymethyl)-6-(methanesulfonamido)-3,4,4a,9a-tetrahydro-1H-pyrano[3,4-b]benzofuran-3-yl]-N-(cyclopropylmethyl)acetamide
C19H26N2O6S (410.15114960000005)
(4S,7R)-4-[(3-chlorophenyl)methyl]-7-phenyl-9-oxa-1,6,12,13-tetrazabicyclo[9.2.1]tetradeca-11(14),12-dien-5-one
7-[(4-Chlorophenyl)methyl]-4-phenyl-9-oxa-1,6,13,14-tetrazabicyclo[9.3.0]tetradeca-11,13-dien-5-one
4-[(3aR,4S,9bR)-4-(hydroxymethyl)-1-[oxo(3-pyridinyl)methyl]-2,3,3a,4,5,9b-hexahydropyrrolo[3,2-c]quinolin-8-yl]benzonitrile
(1R,5S)-3-(2-fluorophenyl)sulfonyl-7-[4-(5-pyrimidinyl)phenyl]-3,6-diazabicyclo[3.1.1]heptane
(6Ar,9S,10aR)-9-(methylsulfanylmethyl)-7-propyl-6,6a,8,9,10,10a-hexahydro-4H-indolo[4,3-fg]quinoline;methanesulfonic acid
2-[(1S,3R,4aS,9aR)-1-(hydroxymethyl)-6-(methanesulfonamido)-3,4,4a,9a-tetrahydro-1H-pyrano[3,4-b]benzofuran-3-yl]-N-(cyclopropylmethyl)acetamide
C19H26N2O6S (410.15114960000005)
(4R,7S)-4-[(4-chlorophenyl)methyl]-7-phenyl-9-oxa-1,6,12,13-tetrazabicyclo[9.2.1]tetradeca-11(14),12-dien-5-one
7-[(3-Chlorophenyl)methyl]-4-phenyl-9-oxa-1,6,13,14-tetrazabicyclo[9.3.0]tetradeca-11,13-dien-5-one
3,5-dicyano-4-(dibutylamino)-N-phenylbenzenesulfonamide
N-[3-(2,3-Dimethyl-1H-indol-1-yl)-2-methylpropyl]-3,5-dinitrobenzamide
2-(hydroxymethyl)-5-(2-oxopropyl)-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one
(2R,5R)-2-(hydroxymethyl)-5-[6-[(1-methoxyindol-3-yl)methylamino]purin-9-yl]oxolan-3-ol
Lactopicrin
Lactucopicrin is an azulenofuran, a cyclic terpene ketone, an enone, a member of phenols, a sesquiterpene lactone and a primary alcohol. It has a role as a plant metabolite, a sedative and an antimalarial. It is functionally related to a 4-hydroxyphenylacetic acid and a lactucin. Lactupicrin is a natural product found in Cichorium endivia, Cichorium spinosum, and other organisms with data available. Lactupicrin (Lactucopicrin) is a characteristic bitter sesquiterpene lactone that can relieve pain. Lactupicrin exhibits atheroprotective effect[1][2]. Lactupicrin (Lactucopicrin) is a characteristic bitter sesquiterpene lactone that can relieve pain. Lactupicrin exhibits atheroprotective effect[1][2].
1-Isomangostin
An organic heterotetracyclic compound that is 3,4-dihydro-2H,12H-pyrano[2,3-a]xanthen-12-one substituted by hydroxy groups at positions 5 and 9, a methoxy group at position 10, two methyl groups at position 2, a prenyl group at position 11 and an oxo group at position 12.
SN-38 carboxylic acid
A 2-hydroxy monocarboxylic acid resulting from the hydrolysis of the delta-lactone ring of SN-38. It is a metabolite of SN-38.
MMV009085
MMV009085 is a potent PfHT1 (Plasmodium?falciparum?hexose transporter)-specific inhibitor and a potential anti-malarial agent . MMV009085 is also a human glucose transporter inhibitor, it has high potency in inhibiting both glucose uptake (IC50: 2.6 μM in glucose uptake assay) and growth of the parasites (EC50: 1.23±0.04 μM against 3D7)[1].
4,5,7,8,17-pentahydroxy-6,14,18-trimethyl-3,10-dioxapentacyclo[9.8.0.0¹,⁷.0⁴,¹⁹.0¹³,¹⁸]nonadec-14-ene-9,16-dione
(4s,4as,5r,6s,8ar,9ar)-4,9a-dimethoxy-3,4a,5-trimethyl-2-oxo-4h,5h,6h,7h,8h,8ah,9h-naphtho[2,3-b]furan-6-yl (2z)-3-(methylsulfanyl)prop-2-enoate
(1'r,2s,4r,4's,5's,8'r,9's,10's,12'r,14's)-4-hydroxy-4-[(1s)-1-hydroxyethyl]-9'-methoxy-3',3',10'-trimethyl-2',7',13'-trioxaspiro[oxolane-2,11'-pentacyclo[8.4.0.0¹,⁵.0⁴,⁸.0¹²,¹⁴]tetradecane]-5,6'-dione
5,9-dihydroxy-10-methoxy-1,1,2-trimethyl-7-(3-methylbut-2-en-1-yl)-2h-furo[2,3-c]xanthen-6-one
7-(4-hydroxy-3-methoxyphenyl)-4,6-dimethoxy-2-(prop-1-en-2-yl)-2h,3h-furo[3,2-g]chromen-5-one
8-hydroxy-13-methoxy-17,17-dimethyl-15-(3-methylbut-2-en-1-yl)-3,16-dioxapentacyclo[11.4.1.0²,¹¹.0²,¹⁵.0⁴,⁹]octadeca-4,6,8,11-tetraene-10,14-dione
16-(3,3-dimethyloxirane-2-carbonyl)-11,11,15-trimethyl-6,10,19-trioxapentacyclo[13.3.1.0²,⁷.0⁹,¹⁸.0¹²,¹⁷]nonadeca-1,3,7,9(18)-tetraen-5-one
(1s,2r,6r,7r,9r,10s,11s,12r,14s)-9,11-dihydroxy-9-(hydroxymethyl)-14-methyl-5-methylidene-4-oxo-3,13-dioxatetracyclo[8.4.0.0²,⁶.0¹²,¹⁴]tetradecan-7-yl (2e)-4-hydroxy-2-methylbut-2-enoate
butyl (1r,3r,4s,5r)-3-{[(2e)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy}-1,4,5-trihydroxycyclohexane-1-carboxylate
11,11-dimethyl-7-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-4,10-dioxatricyclo[7.4.0.0²,⁶]trideca-1(9),2(6),7-triene-5,13-dione
methyl (1r,9r,10r,12r)-4-methoxy-15,20-dioxo-19-oxa-8,16-diazahexacyclo[8.8.2.2⁹,¹².0¹,⁹.0²,⁷.0¹²,¹⁶]docosa-2,4,6,13-tetraene-8-carboxylate
(4r,8s)-18-hydroxy-15-(3-hydroxy-3-methylbutyl)-2-methoxy-7,9,13-trioxapentacyclo[10.8.0.0³,¹⁰.0⁴,⁸.0¹⁴,¹⁹]icosa-1,3(10),5,11,14,16,18-heptaen-20-one
methyl (1s,12r,19r,21r,24r)-21-hydroxy-20-oxo-5,7-dioxa-2,15-diazaheptacyclo[17.2.2.1¹²,¹⁵.0¹,¹².0³,¹¹.0⁴,⁸.0¹⁹,²⁴]tetracosa-3,8,10,17-tetraene-21-carboxylate
(2r,3r,4s,5r,6r)-2-{[(1z)-3-(3,4-dihydroxyphenyl)prop-1-en-1-yl]oxy}-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl (2z)-2-methylbut-2-enoate
(2r)-7-(4-hydroxy-3-methoxyphenyl)-4,6-dimethoxy-2-(prop-1-en-2-yl)-2h,3h-furo[3,2-g]chromen-5-one
1,3,6-trihydroxy-5-methoxy-2,7-bis(3-methylbut-2-en-1-yl)xanthen-9-one
3-[(7s,9r)-7-(2h-1,3-benzodioxol-5-yl)-5-methoxy-8-oxatricyclo[4.3.0.0⁷,⁹]nona-1,3,5-trien-3-yl]propyl (2r)-2-methylbutanoate
(1r,2r,3r,6r,8s,12r,13s,14r,15r,16s,17r)-2,3,12,15,16-pentahydroxy-9,13,17-trimethyl-5,18-dioxapentacyclo[12.5.0.0¹,⁶.0²,¹⁷.0⁸,¹³]nonadec-9-ene-4,11-dione
(2s)-5,9-dihydroxy-10-methoxy-1,1,2-trimethyl-7-(3-methylbut-2-en-1-yl)-2h-furo[2,3-c]xanthen-6-one
(1s,4s,5s,6r,7s,8s,11s,13r,17r,18r,19s)-4,5,7,8,17-pentahydroxy-6,14,18-trimethyl-3,10-dioxapentacyclo[9.8.0.0¹,⁷.0⁴,¹⁹.0¹³,¹⁸]nonadec-14-ene-9,16-dione
(2s,4r)-n-{2-chloro-1-[(2r,3r,4s,5r,6r)-3,4,5-trihydroxy-6-(methylsulfanyl)oxan-2-yl]propyl}-4-propylpyrrolidine-2-carboximidic acid
C17H31ClN2O5S (410.16421060000005)