Amorphigenin (BioDeep_00000268932)

   

PANOMIX_OTCML-2023


代谢物信息卡片


(2R) -8,9-Dimethoxy-2alpha- [1- (hydroxymethyl) ethenyl] -1,2,12,12aalpha-tetrahydro [1] benzopyrano [3,4-b] furo [2,3-h] [1] benzopyran-6 (6aalphaH) -one

化学式: C23H22O7 (410.1365)
中文名称:
谱图信息: 最多检出来源 Homo sapiens(lipidomics) 38.41%

分子结构信息

SMILES: c(c51)c(c(OC)cc(OCC(C25)Oc(c43)c(ccc(OC(C4)C(CO)=C)3)C(=O)2)1)OC
InChI: InChI=1S/C23H22O7/c1-11(9-24)16-7-14-15(29-16)5-4-12-22(25)21-13-6-18(26-2)19(27-3)8-17(13)28-10-20(21)30-23(12)14/h4-6,8,16,20-21,24H,1,7,9-10H2,2-3H3

描述信息

Origin: Plant, Pyrans
relative retention time with respect to 9-anthracene Carboxylic Acid is 1.086
relative retention time with respect to 9-anthracene Carboxylic Acid is 1.088

同义名列表

10 个代谢物同义名

Amorphigenin; 8-Hydroxyrotenone; (2R) -8,9-Dimethoxy-2alpha- [1- (hydroxymethyl) ethenyl] -1,2,12,12aalpha-tetrahydro [1] benzopyrano [3,4-b] furo [2,3-h] [1] benzopyran-6 (6aalphaH) -one; (1S,6R,13S)-6-(3-hydroxyprop-1-en-2-yl)-16,17-dimethoxy-2,7,20-trioxapentacyclo(11.8.0.03,11.04,8.014,19)henicosa-3(11),4(8),9,14,16,18-hexaen-12-one; (1S,6R,13S)-6-(3-hydroxyprop-1-en-2-yl)-16,17-dimethoxy-2,7,20-trioxapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),9,14,16,18-hexaen-12-one; (2r,6as,12as)-2-(3-hydroxyprop-1-en-2-yl)-8,9-dimethoxy-1,2,12,12a-tetrahydrochromeno[3,4-b]furo[2,3-h]chromen-6(6ah)-one; 2-(3-Hydroxyprop-1-en-2-yl)-8,9-dimethoxy-1,2,12,12a-tetrahydrofuro[2',3':7,8][1]benzopyrano[2,3-c][1]benzopyran-6(6aH)-one; 3'-Hydroxyrotenone; 8'-hydroxyrotenone; Rotenone, 8'-hydroxy-



数据库引用编号

20 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

2 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(1)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(1)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Hongzhen Zhong, Yufang Zuo, Xin Wu, Yan Peng, Huiping He, Jun Yang, Chengnong Guan, Zumin Xu. [Synergistic Antitumor Effect of Amorphigenin Combined with Cisplatin in Human Lung Adenocarcinoma A549/DDP Cells]. Zhongguo fei ai za zhi = Chinese journal of lung cancer. 2016 Dec; 19(12):805-812. doi: 10.3779/j.issn.1009-3419.2016.12.02. [PMID: 27978865]
  • Mingshan Ji, Yaping Liang, Zumin Gu, Xiuwei Li. Inhibitory Effects of Amorphigenin on the Mitochondrial Complex I of Culex pipiens pallens Coquillett (Diptera: Culicidae). International journal of molecular sciences. 2015 Aug; 16(8):19713-27. doi: 10.3390/ijms160819713. [PMID: 26307964]
  • Yaping Liang, Xiuwei Li, Zumin Gu, Peiwen Qin, Mingshan Ji. Toxicity of amorphigenin from the seeds of Amorpha fruticosa against the larvae of Culex pipiens pallens (Diptera: Culicidae). Molecules (Basel, Switzerland). 2015 Feb; 20(2):3238-54. doi: 10.3390/molecules20023238. [PMID: 25690287]
  • Young-Won Chin, Ladislaus K Mdee, Zakaria H Mbwambo, Qiuwen Mi, Hee-Byung Chai, Gordon M Cragg, Steven M Swanson, A Douglas Kinghorn. Prenylated flavonoids from the root bark of Berchemia discolor, a Tanzanian medicinal plant. Journal of natural products. 2006 Nov; 69(11):1649-52. doi: 10.1021/np060418w. [PMID: 17125241]
  • T Konoshima, H Terada, M Kokumai, M Kozuka, H Tokuda, J R Estes, L Li, H K Wang, K H Lee. Studies on inhibitors of skin tumor promotion, XII. Rotenoids from Amorpha fruticosa. Journal of natural products. 1993 Jun; 56(6):843-8. doi: 10.1021/np50096a006. [PMID: 8350086]
  • L Li, H K Wang, J J Chang, A T McPhail, D R McPhail, H Terada, T Konoshima, M Kokumai, M Kozuka, J R Estes. Antitumor agents, 138. Rotenoids and isoflavones as cytotoxic constitutents from Amorpha fruticosa. Journal of natural products. 1993 May; 56(5):690-8. doi: 10.1021/np50095a005. [PMID: 8326318]