Exact Mass: 397.215

CONFIDENCE Reference Standard (Level 1); INTERNAL_ID 2304 INTERNAL_ID 2304; CONFIDENCE Reference Standard (Level 1)

3,4-dihydroxy-2-methyl-4-farnesyl-3H-quinolin-1-ium-1-olate

3,4-Dihydroxy-2-methy-4-[(2E,6E)-farnesyl]-3,4-dihydroquinoline 1-oxide

A member of the class of quinoline N-oxides that is 2-methyl-1-oxo-4-3,4-dihydroquinoline-3,4-diol carrying an additional (2E,6E)-farnesyl group at position 4.

Apatinib

C24H23N5O (397.1903)

C274 - Antineoplastic Agent > C2189 - Signal Transduction Inhibitor > C129824 - Antineoplastic Protein Inhibitor C471 - Enzyme Inhibitor > C129825 - Antineoplastic Enzyme Inhibitor D004791 - Enzyme Inhibitors > D047428 - Protein Kinase Inhibitors D000970 - Antineoplastic Agents

Heliosupine

7-Angelyl-9-echimidinylheliotridine

Phytosphingosine-1-P

{[(2R,3R,4R)-2-amino-3,4-dihydroxyoctadecyl]oxy}phosphonic acid

Phytosphingosine-1-P is an intermediate in sphingolipid metabolism pathway. It is the enzymatic oxidation product of 4-hydroxysphinganine. Sphingolipids are essential components of the plasma membrane in all eukaryotic cells. S. cerevisiae cells make three complex sphingolipids: inositol-phosphoceramide (IPC), mannose-inositol-phosphoceramide (MIPC), and mannosyl-diinositol-phosphorylceramide (M(IP)2C) [ Dickson02 ]. In the yeast plasma membrane sphingolipids concentrate with ergosterol to form lipid rafts, specialized membrane microdomains implicated in a variety of cellular processes, including sorting of membrane proteins and lipids, as well as organizing and regulating signaling cascades [ Bagnat02 ]. Intermediates in sphingolipid biosynthesis have been shown to play important roles as signaling molecules and growth regulators. Sphingolipid long chain bases (LCBs), dihydrosphingosine (DHS) and phytosphingosine (PHS), have been implicated as secondary messengers in signaling pathways that regulate heat stress response. Other intermediates, phytoceramide and long-chain base phosphates (LCBPs), have been shown to be components of tightly-controlled ceramide/LCBP rheostat, which regulates cell growth. Since phosphoinositol-containing sphingolipids are unique to fungi, the sphingolipid biosynthesis pathway is considered a target for antifungal drugs. Phytosphingosine-1-p, also known as phs-1-phosphate, is a member of the class of compounds known as phosphosphingolipids. Phosphosphingolipids are sphingolipids with a structure based on a sphingoid base that is attached to a phosphate head group. They differ from phosphonospingolipids which have a phosphonate head group. Phytosphingosine-1-p is practically insoluble (in water) and a moderately acidic compound (based on its pKa). Phytosphingosine-1-p can be found in a number of food items such as dandelion, common verbena, turmeric, and fennel, which makes phytosphingosine-1-p a potential biomarker for the consumption of these food products.

Drotaverine

(1Z)-1-[(3,4-diethoxyphenyl)methylidene]-6,7-diethoxy-1,2,3,4-tetrahydroisoquinoline

Drotaverine (INN, also known as drotaverin) is an antispasmodic drug, structurally related to papaverine. Drotaverine is a selective inhibitor of phosphodiesterase 4, and has no anticholinergic effects. Drotaverine has been shown to possess dose-dependant analgesic effects in animal models. One small study has shown drotaverine to be eliminated mainly non-renally. A - Alimentary tract and metabolism > A03 - Drugs for functional gastrointestinal disorders > A03A - Drugs for functional gastrointestinal disorders > A03AD - Papaverine and derivatives C78272 - Agent Affecting Nervous System > C66880 - Anticholinergic Agent > C29704 - Antimuscarinic Agent D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents > D010276 - Parasympatholytics D002492 - Central Nervous System Depressants > D009294 - Narcotics > D053610 - Opiate Alkaloids D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents C78272 - Agent Affecting Nervous System > C29698 - Antispasmodic Agent D002491 - Central Nervous System Agents > D000700 - Analgesics D002317 - Cardiovascular Agents > D014665 - Vasodilator Agents

Tetradeca-9,11-dienedioylcarnitine

3-[(13-carboxytrideca-9,11-dienoyl)oxy]-4-(trimethylazaniumyl)butanoate

C21H35NO6 (397.2464)

Tetradeca-9,11-dienedioylcarnitine is an acylcarnitine. More specifically, it is an tetradeca-9,11-dienedioic acid ester of carnitine. Acylcarnitines were first discovered more than 70 year ago (PMID: 13825279). It is believed that there are more than 1000 types of acylcarnitines in the human body. The general role of acylcarnitines is to transport acyl-groups (organic acids and fatty acids) from the cytoplasm into the mitochondria so that they can be broken down to produce energy. This process is known as beta-oxidation. According to a recent review [Dambrova et al. 2021, Physiological Reviews], acylcarnitines (ACs) can be classified into 9 different categories depending on the type and size of their acyl-group: 1) short-chain ACs; 2) medium-chain ACs; 3) long-chain ACs; 4) very long-chain ACs; 5) hydroxy ACs; 6) branched chain ACs; 7) unsaturated ACs; 8) dicarboxylic ACs and 9) miscellaneous ACs. Short-chain ACs have acyl-groups with two to five carbons (C2-C5), medium-chain ACs have acyl-groups with six to thirteen carbons (C6-C13), long-chain ACs have acyl-groups with fourteen to twenty once carbons (C14-C21) and very long-chain ACs have acyl groups with more than 22 carbons. Tetradeca-9,11-dienedioylcarnitine is therefore classified as a long chain AC. As a long-chain acylcarnitine Tetradeca-9,11-dienedioylcarnitine is generally formed through esterification with long-chain fatty acids obtained from the diet. The main function of most long-chain acylcarnitines is to ensure long chain fatty acid transport into the mitochondria (PMID: 22804748). Altered levels of long-chain acylcarnitines can serve as useful markers for inherited disorders of long-chain fatty acid metabolism. Carnitine palmitoyltransferase I (CPT I, EC:2.3.1.21) is involved in the synthesis of long-chain acylcarnitines (more than C12) on the mitochondrial outer membrane. Elevated serum/plasma levels of long-chain acylcarnitines are not only markers for incomplete FA oxidation but also are indicators of altered carbohydrate and lipid metabolism. High serum concentrations of long-chain acylcarnitines in the postprandial or fed state are markers of insulin resistance and arise from insulins inability to inhibit CPT-1-dependent fatty acid metabolism in muscles and the heart (PMID: 19073774). Increased intracellular content of long-chain acylcarnitines is thought to serve as a feedback inhibition mechanism of insulin action (PMID: 23258903). In healthy subjects, increased concentrations of insulin effectively inhibits long-chain acylcarnitine production. Several studies have also found increased levels of circulating long-chain acylcarnitines in chronic heart failure patients (PMID: 26796394). The study of acylcarnitines is an active area of research and it is likely that many novel acylcarnitines will be discovered in the coming years. It is also likely that many novel roles in health and disease will be uncovered. An excellent review of the current state of knowledge for acylcarnitines is available at [Dambrova et al. 2021, Physiological Reviews].

(6E,9E)-Tetradeca-6,9-dienedioylcarnitine

3-[(13-carboxytrideca-6,9-dienoyl)oxy]-4-(trimethylazaniumyl)butanoate

C21H35NO6 (397.2464)

(6E,9E)-Tetradeca-6,9-dienedioylcarnitine is an acylcarnitine. More specifically, it is an (6E,9E)-tetradeca-6,9-dienedioic acid ester of carnitine. Acylcarnitines were first discovered more than 70 year ago (PMID: 13825279). It is believed that there are more than 1000 types of acylcarnitines in the human body. The general role of acylcarnitines is to transport acyl-groups (organic acids and fatty acids) from the cytoplasm into the mitochondria so that they can be broken down to produce energy. This process is known as beta-oxidation. According to a recent review [Dambrova et al. 2021, Physiological Reviews], acylcarnitines (ACs) can be classified into 9 different categories depending on the type and size of their acyl-group: 1) short-chain ACs; 2) medium-chain ACs; 3) long-chain ACs; 4) very long-chain ACs; 5) hydroxy ACs; 6) branched chain ACs; 7) unsaturated ACs; 8) dicarboxylic ACs and 9) miscellaneous ACs. Short-chain ACs have acyl-groups with two to five carbons (C2-C5), medium-chain ACs have acyl-groups with six to thirteen carbons (C6-C13), long-chain ACs have acyl-groups with fourteen to twenty once carbons (C14-C21) and very long-chain ACs have acyl groups with more than 22 carbons. (6E,9E)-Tetradeca-6,9-dienedioylcarnitine is therefore classified as a long chain AC. As a long-chain acylcarnitine (6E,9E)-Tetradeca-6,9-dienedioylcarnitine is generally formed through esterification with long-chain fatty acids obtained from the diet. The main function of most long-chain acylcarnitines is to ensure long chain fatty acid transport into the mitochondria (PMID: 22804748). Altered levels of long-chain acylcarnitines can serve as useful markers for inherited disorders of long-chain fatty acid metabolism. Carnitine palmitoyltransferase I (CPT I, EC:2.3.1.21) is involved in the synthesis of long-chain acylcarnitines (more than C12) on the mitochondrial outer membrane. Elevated serum/plasma levels of long-chain acylcarnitines are not only markers for incomplete FA oxidation but also are indicators of altered carbohydrate and lipid metabolism. High serum concentrations of long-chain acylcarnitines in the postprandial or fed state are markers of insulin resistance and arise from insulins inability to inhibit CPT-1-dependent fatty acid metabolism in muscles and the heart (PMID: 19073774). Increased intracellular content of long-chain acylcarnitines is thought to serve as a feedback inhibition mechanism of insulin action (PMID: 23258903). In healthy subjects, increased concentrations of insulin effectively inhibits long-chain acylcarnitine production. Several studies have also found increased levels of circulating long-chain acylcarnitines in chronic heart failure patients (PMID: 26796394). The study of acylcarnitines is an active area of research and it is likely that many novel acylcarnitines will be discovered in the coming years. It is also likely that many novel roles in health and disease will be uncovered. An excellent review of the current state of knowledge for acylcarnitines is available at [Dambrova et al. 2021, Physiological Reviews].

(2E,4Z)-Tetradeca-2,4-dienedioylcarnitine

3-[(13-carboxytrideca-2,4-dienoyl)oxy]-4-(trimethylazaniumyl)butanoate

C21H35NO6 (397.2464)

(2E,4Z)-Tetradeca-2,4-dienedioylcarnitine is an acylcarnitine. More specifically, it is an (2E,4Z)-tetradeca-2,4-dienedioic acid ester of carnitine. Acylcarnitines were first discovered more than 70 year ago (PMID: 13825279). It is believed that there are more than 1000 types of acylcarnitines in the human body. The general role of acylcarnitines is to transport acyl-groups (organic acids and fatty acids) from the cytoplasm into the mitochondria so that they can be broken down to produce energy. This process is known as beta-oxidation. According to a recent review [Dambrova et al. 2021, Physiological Reviews], acylcarnitines (ACs) can be classified into 9 different categories depending on the type and size of their acyl-group: 1) short-chain ACs; 2) medium-chain ACs; 3) long-chain ACs; 4) very long-chain ACs; 5) hydroxy ACs; 6) branched chain ACs; 7) unsaturated ACs; 8) dicarboxylic ACs and 9) miscellaneous ACs. Short-chain ACs have acyl-groups with two to five carbons (C2-C5), medium-chain ACs have acyl-groups with six to thirteen carbons (C6-C13), long-chain ACs have acyl-groups with fourteen to twenty once carbons (C14-C21) and very long-chain ACs have acyl groups with more than 22 carbons. (2E,4Z)-Tetradeca-2,4-dienedioylcarnitine is therefore classified as a long chain AC. As a long-chain acylcarnitine (2E,4Z)-Tetradeca-2,4-dienedioylcarnitine is generally formed through esterification with long-chain fatty acids obtained from the diet. The main function of most long-chain acylcarnitines is to ensure long chain fatty acid transport into the mitochondria (PMID: 22804748). Altered levels of long-chain acylcarnitines can serve as useful markers for inherited disorders of long-chain fatty acid metabolism. Carnitine palmitoyltransferase I (CPT I, EC:2.3.1.21) is involved in the synthesis of long-chain acylcarnitines (more than C12) on the mitochondrial outer membrane. Elevated serum/plasma levels of long-chain acylcarnitines are not only markers for incomplete FA oxidation but also are indicators of altered carbohydrate and lipid metabolism. High serum concentrations of long-chain acylcarnitines in the postprandial or fed state are markers of insulin resistance and arise from insulins inability to inhibit CPT-1-dependent fatty acid metabolism in muscles and the heart (PMID: 19073774). Increased intracellular content of long-chain acylcarnitines is thought to serve as a feedback inhibition mechanism of insulin action (PMID: 23258903). In healthy subjects, increased concentrations of insulin effectively inhibits long-chain acylcarnitine production. Several studies have also found increased levels of circulating long-chain acylcarnitines in chronic heart failure patients (PMID: 26796394). The study of acylcarnitines is an active area of research and it is likely that many novel acylcarnitines will be discovered in the coming years. It is also likely that many novel roles in health and disease will be uncovered. An excellent review of the current state of knowledge for acylcarnitines is available at [Dambrova et al. 2021, Physiological Reviews].

1-(3,4-Diethoxybenzyl)-6,7-diethoxy-3,4-dihydroisoquinoline

1-[(3,4-diethoxyphenyl)methyl]-6,7-diethoxy-3,4-dihydroisoquinoline

4-Tetradecanamidobenzylphosphonic acid

[(4-tetradecanamidophenyl)methyl]phosphonic acid

C21H36NO4P (397.2382)

Comfrey

7-({[2,3-dihydroxy-2-(propan-2-yl)butanoyl]oxy}methyl)-1-[(2-methylbut-2-enoyl)oxy]-1,2,3,4,5,7a-hexahydropyrrolizin-4-ium-4-olate

Apatinib

N-[4-(1-cyanocyclopentyl)phenyl]-2-{[(pyridin-4-yl)methyl]amino}pyridine-3-carboxamide

C24H23N5O (397.1903)

4-(5H-Dibenzo[a,d]cyclohepten-5-ylidene)-1-[4-(2H-tetrazol-5-yl)butyl]-piperidine

1-[4-(2H-1,2,3,4-tetrazol-5-yl)butyl]-4-{tricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3,5,7,9,11,13-heptaen-2-ylidene}piperidine

C25H27N5 (397.2266)

Methyl N-({(2s,3s)-3-[(Propylamino)carbonyl]oxiran-2-Yl}carbonyl)-L-Isoleucyl-L-Prolinate

N2-{1-[2-(methoxycarbonyl)pyrrolidin-1-yl]-3-methyl-1-oxopentan-2-yl}-N3-propyloxirane-2,3-dicarboximidate

C19H31N3O6 (397.2213)

6-[[3-Fluoro-5-(4-methoxyoxan-4-yl)phenoxy]methyl]-1-methylquinolin-2-one

6-((3-Fluoro-5-(4-methoxy-3,4,5,6-tetrahydro-2H-pyran-4-yl)phenoxy)methyl)-1-methylquinol-2-one

C23H24FNO4 (397.1689)

Reduced ketanserin

3-(2-{4-[(4-fluorophenyl)(hydroxy)methyl]piperidin-1-yl}ethyl)-1,2,3,4-tetrahydroquinazoline-2,4-dione

N-Acetyl-9-aminominocycline, (4R)-

6-[3-[1-(Dimethylamino)-2-methylpentan-3-yl]phenoxy]-3,4,5-trihydroxyoxane-2-carboxylic acid

A natural product found in Aconitum vilmorinianum and Delphinium denudatum.

Sorbistin A1

C15H31N3O9 (397.206)

Latrunculin C

C20H31NO5S (397.1923)

Cyclomarazine A

C23H31N3O3 (397.2365)

methyl 2-[1-(4-fluorobenzyl)-1h-indazole-3-carboxamido]-3,3-dimethylbutanoate

CHM-081

C27H27NO2 (397.2042)

EMB-FUBINACA

ZINC4322591

C19H31N3O2S2 (397.1858)

TCMDC-136560

C20H27N7O2 (397.2226)

CHEMBL1836611

C23H28ClN3O (397.1921)

C20H31NO7

AM31 beta

C15H31N3O9 (397.206)

Gly-Pro-Ala-Gly-Pro

Aspochalasin A

arcutin

octadeca-9,12,15-trienoylanthranilic acid

(2E,12E)-pipertridecadienamide

sarcodifurine B

neolamarckine A

C22H27N3O4 (397.2001)

15-acetyloxysongoramine|15-Acetylsongoramine

2,3-Epoxyechiumine

sarcodifurine A

His Asp Leu

histidylasparagyllysine

His Ile Glu

Leu His Asp

Gln Asn His

His Asn Gln

Thr Phe Met

Lys Asn His

Ile Cys Tyr

Phe Met Thr

Met Thr Phe

asparagylhistidyllysine

His Lys Asn

(±)14(15)-EET-SI

C21H35NO4S (397.2287)

Leu Asp His

Asp Leu His

Asn His Gln

His Glu Ile

Lys His Asn

Met Phe Thr

Glu Ile His

AT-56

4-(5H-Dibenzo[a,d]cyclohepten-5-ylidene)-1-[4-(2H-tetrazol-5-yl)butyl]-piperidine

C25H27N5 (397.2266)

Cys Tyr Ile

Ile His Glu

Asp His Leu

Asn Lys His

His Gln Asn

Thr Met Phe

Ile Glu His

Asn Gln His

Glu His Ile

dihydroprecondylocarpine acetate

C23H29N2O4+ (397.2127)

An organic cation which is an intermediate in the biosynthetic pathway leading to the synthesis of the monoterpenoid indole alkaloids, catharanthine and tabersonine.

Heliosupin

(1S,7aR)-7-[({(2S)-2,3-dihydroxy-2-[(1S)-1-hydroxyethyl]-3-methylbutanoyl}oxy)methyl]-2,3,5,7a-tetrahydro-1H-pyrrolo[1,2-a]pyrrol-1-yl (2Z)-2-methylbut-2-enoate

Heliosupine is an azabicycloalkane compound having angelyloxy and echimidinyloxymethyl substituents attached to the ring system. It is an azabicycloalkane, a diester and a 2-methylbut-2-enoic acid. It is functionally related to an angelic acid and an isocrotonic acid. Heliosupine is a natural product found in Cynoglossum australe, Paracaryum rugulosum, and other organisms with data available. See also: Comfrey Leaf (part of); Comfrey Root (part of). An azabicycloalkane compound having angelyloxy and echimidinyloxymethyl substituents attached to the ring system.

Lipothiazole A

C19H27NO8_2-(4,5-Dihydroxy-7,7a-dimethyl-2-oxo-4,5,6,7,7a,7b-hexahydronaphtho[1,2-b]oxiren-1a(2H)-yl)-2-propen-1-yl 4-amino-2,3-dihydroxybutanoate

NCGC00381157-01_C19H27NO8_2-(4,5-Dihydroxy-7,7a-dimethyl-2-oxo-4,5,6,7,7a,7b-hexahydronaphtho[1,2-b]oxiren-1a(2H)-yl)-2-propen-1-yl 4-amino-2,3-dihydroxybutanoate

MMV026356

C20H27N7O2 (397.2226)

MMV688279

C23H28N3OCl (397.1921)

Mycofactocinol-1

Phytosphingosine-1-P

Ala Gly His Asn

(2S)-2-[(2S)-2-{2-[(2S)-2-aminopropanamido]acetamido}-3-(1H-imidazol-4-yl)propanamido]-3-carbamoylpropanoic acid

Ala Gly Asn His

(2S)-2-[(2S)-2-{2-[(2S)-2-aminopropanamido]acetamido}-3-carbamoylpropanamido]-3-(1H-imidazol-4-yl)propanoic acid

Ala His Gly Asn

(2S)-2-{2-[(2S)-2-[(2S)-2-aminopropanamido]-3-(1H-imidazol-4-yl)propanamido]acetamido}-3-carbamoylpropanoic acid

Ala His Asn Gly

2-[(2S)-2-[(2S)-2-[(2S)-2-aminopropanamido]-3-(1H-imidazol-4-yl)propanamido]-3-carbamoylpropanamido]acetic acid

Ala Asn Gly His

(2S)-2-{2-[(2S)-2-[(2S)-2-aminopropanamido]-3-carbamoylpropanamido]acetamido}-3-(1H-imidazol-4-yl)propanoic acid

Ala Asn His Gly

2-[(2S)-2-[(2S)-2-[(2S)-2-aminopropanamido]-3-carbamoylpropanamido]-3-(1H-imidazol-4-yl)propanamido]acetic acid

Ala Asn Pro Pro

(2S)-1-{[(2S)-1-[(2S)-2-[(2S)-2-aminopropanamido]-3-carbamoylpropanoyl]pyrrolidin-2-yl]carbonyl}pyrrolidine-2-carboxylic acid

Ala Pro Asn Pro

(2S)-1-[(2S)-2-{[(2S)-1-[(2S)-2-aminopropanoyl]pyrrolidin-2-yl]formamido}-3-carbamoylpropanoyl]pyrrolidine-2-carboxylic acid

Ala Pro Pro Asn

(2S)-2-{[(2S)-1-{[(2S)-1-[(2S)-2-aminopropanoyl]pyrrolidin-2-yl]carbonyl}pyrrolidin-2-yl]formamido}-3-carbamoylpropanoic acid

Gly Ala His Asn

(2S)-2-[(2S)-2-[(2S)-2-(2-aminoacetamido)propanamido]-3-(1H-imidazol-4-yl)propanamido]-3-carbamoylpropanoic acid

Gly Ala Asn His

(2S)-2-[(2S)-2-[(2S)-2-(2-aminoacetamido)propanamido]-3-carbamoylpropanamido]-3-(1H-imidazol-4-yl)propanoic acid

Gly Gly His Lys

(2S)-6-amino-2-[(2S)-2-[2-(2-aminoacetamido)acetamido]-3-(1H-imidazol-4-yl)propanamido]hexanoic acid

Gly Gly His Gln

(2S)-2-[(2S)-2-[2-(2-aminoacetamido)acetamido]-3-(1H-imidazol-4-yl)propanamido]-4-carbamoylbutanoic acid

Gly Gly Lys His

(2S)-2-[(2S)-6-amino-2-[2-(2-aminoacetamido)acetamido]hexanamido]-3-(1H-imidazol-4-yl)propanoic acid

Gly Gly Gln His

(2S)-2-[(2S)-2-[2-(2-aminoacetamido)acetamido]-4-carbamoylbutanamido]-3-(1H-imidazol-4-yl)propanoic acid

Gly His Ala Asn

(2S)-2-[(2S)-2-[(2S)-2-(2-aminoacetamido)-3-(1H-imidazol-4-yl)propanamido]propanamido]-3-carbamoylpropanoic acid

Gly His Gly Lys

(2S)-6-amino-2-{2-[(2S)-2-(2-aminoacetamido)-3-(1H-imidazol-4-yl)propanamido]acetamido}hexanoic acid

Gly His Gly Gln

(2S)-2-{2-[(2S)-2-(2-aminoacetamido)-3-(1H-imidazol-4-yl)propanamido]acetamido}-4-carbamoylbutanoic acid

Gly His Lys Gly

2-[(2S)-6-amino-2-[(2S)-2-(2-aminoacetamido)-3-(1H-imidazol-4-yl)propanamido]hexanamido]acetic acid

Gly His Asn Ala

(2S)-2-[(2S)-2-[(2S)-2-(2-aminoacetamido)-3-(1H-imidazol-4-yl)propanamido]-3-carbamoylpropanamido]propanoic acid

Gly His Gln Gly

2-[(2S)-2-[(2S)-2-(2-aminoacetamido)-3-(1H-imidazol-4-yl)propanamido]-4-carbamoylbutanamido]acetic acid

Gly Lys Gly His

(2S)-2-{2-[(2S)-6-amino-2-(2-aminoacetamido)hexanamido]acetamido}-3-(1H-imidazol-4-yl)propanoic acid

Gly Lys His Gly

2-[(2S)-2-[(2S)-6-amino-2-(2-aminoacetamido)hexanamido]-3-(1H-imidazol-4-yl)propanamido]acetic acid

Gly Lys Pro Pro

(2S)-1-{[(2S)-1-[(2S)-6-amino-2-(2-aminoacetamido)hexanoyl]pyrrolidin-2-yl]carbonyl}pyrrolidine-2-carboxylic acid

Gly Asn Ala His

(2S)-2-[(2S)-2-[(2S)-2-(2-aminoacetamido)-3-carbamoylpropanamido]propanamido]-3-(1H-imidazol-4-yl)propanoic acid

Gly Asn His Ala

(2S)-2-[(2S)-2-[(2S)-2-(2-aminoacetamido)-3-carbamoylpropanamido]-3-(1H-imidazol-4-yl)propanamido]propanoic acid

Gly Pro Lys Pro

(2S)-1-[(2S)-6-amino-2-{[(2S)-1-(2-aminoacetyl)pyrrolidin-2-yl]formamido}hexanoyl]pyrrolidine-2-carboxylic acid

Gly Pro Pro Lys

(2S)-6-amino-2-{[(2S)-1-{[(2S)-1-(2-aminoacetyl)pyrrolidin-2-yl]carbonyl}pyrrolidin-2-yl]formamido}hexanoic acid

Gly Pro Pro Gln

(2S)-2-{[(2S)-1-{[(2S)-1-(2-aminoacetyl)pyrrolidin-2-yl]carbonyl}pyrrolidin-2-yl]formamido}-4-carbamoylbutanoic acid

Gly Pro Gln Pro

(2S)-1-[(2S)-2-{[(2S)-1-(2-aminoacetyl)pyrrolidin-2-yl]formamido}-4-carbamoylbutanoyl]pyrrolidine-2-carboxylic acid

Gly Gln Gly His

(2S)-2-{2-[(2S)-2-(2-aminoacetamido)-4-carbamoylbutanamido]acetamido}-3-(1H-imidazol-4-yl)propanoic acid

Gly Gln His Gly

2-[(2S)-2-[(2S)-2-(2-aminoacetamido)-4-carbamoylbutanamido]-3-(1H-imidazol-4-yl)propanamido]acetic acid

Gly Gln Pro Pro

(2S)-1-{[(2S)-1-[(2S)-2-(2-aminoacetamido)-4-carbamoylbutanoyl]pyrrolidin-2-yl]carbonyl}pyrrolidine-2-carboxylic acid

His Ala Gly Asn

(2S)-2-{2-[(2S)-2-[(2S)-2-amino-3-(1H-imidazol-4-yl)propanamido]propanamido]acetamido}-3-carbamoylpropanoic acid

His Ala Asn Gly

2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-(1H-imidazol-4-yl)propanamido]propanamido]-3-carbamoylpropanamido]acetic acid

His Gly Ala Asn

(2S)-2-[(2S)-2-{2-[(2S)-2-amino-3-(1H-imidazol-4-yl)propanamido]acetamido}propanamido]-3-carbamoylpropanoic acid

His Gly Gly Lys

(2S)-6-amino-2-(2-{2-[(2S)-2-amino-3-(1H-imidazol-4-yl)propanamido]acetamido}acetamido)hexanoic acid

His Gly Gly Gln

(2S)-2-(2-{2-[(2S)-2-amino-3-(1H-imidazol-4-yl)propanamido]acetamido}acetamido)-4-carbamoylbutanoic acid

His Gly Lys Gly

2-[(2S)-6-amino-2-{2-[(2S)-2-amino-3-(1H-imidazol-4-yl)propanamido]acetamido}hexanamido]acetic acid

His Gly Asn Ala

(2S)-2-[(2S)-2-{2-[(2S)-2-amino-3-(1H-imidazol-4-yl)propanamido]acetamido}-3-carbamoylpropanamido]propanoic acid

His Gly Gln Gly

2-[(2S)-2-{2-[(2S)-2-amino-3-(1H-imidazol-4-yl)propanamido]acetamido}-4-carbamoylbutanamido]acetic acid

His Lys Gly Gly

2-{2-[(2S)-6-amino-2-[(2S)-2-amino-3-(1H-imidazol-4-yl)propanamido]hexanamido]acetamido}acetic acid

His Asn Ala Gly

2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-(1H-imidazol-4-yl)propanamido]-3-carbamoylpropanamido]propanamido]acetic acid

His Asn Gly Ala

(2S)-2-{2-[(2S)-2-[(2S)-2-amino-3-(1H-imidazol-4-yl)propanamido]-3-carbamoylpropanamido]acetamido}propanoic acid

His Gln Gly Gly

2-{2-[(2S)-2-[(2S)-2-amino-3-(1H-imidazol-4-yl)propanamido]-4-carbamoylbutanamido]acetamido}acetic acid

Gln His Asn

Leu Glu His

Thr Phe Met

Asn His Lys

His Asn Lys

Cys Ile Tyr

Lys Gly Gly His

(2S)-2-(2-{2-[(2S)-2,6-diaminohexanamido]acetamido}acetamido)-3-(1H-imidazol-4-yl)propanoic acid

Lys Gly His Gly

2-[(2S)-2-{2-[(2S)-2,6-diaminohexanamido]acetamido}-3-(1H-imidazol-4-yl)propanamido]acetic acid

Lys Gly Pro Pro

(2S)-1-{[(2S)-1-{2-[(2S)-2,6-diaminohexanamido]acetyl}pyrrolidin-2-yl]carbonyl}pyrrolidine-2-carboxylic acid

Lys His Gly Gly

2-{2-[(2S)-2-[(2S)-2,6-diaminohexanamido]-3-(1H-imidazol-4-yl)propanamido]acetamido}acetic acid

Lys Pro Gly Pro

(2S)-1-(2-{[(2S)-1-[(2S)-2,6-diaminohexanoyl]pyrrolidin-2-yl]formamido}acetyl)pyrrolidine-2-carboxylic acid

Lys Pro Pro Gly

2-{[(2S)-1-{[(2S)-1-[(2S)-2,6-diaminohexanoyl]pyrrolidin-2-yl]carbonyl}pyrrolidin-2-yl]formamido}acetic acid

Tyr Cys Ile

Cys Leu Tyr

Cys Tyr Leu

Tyr Leu Cys

Phe Met Thr

Ile Cys Tyr

Glu His Leu

Leu Cys Tyr

Asn Ala Gly His

(2S)-2-{2-[(2S)-2-[(2S)-2-amino-3-carbamoylpropanamido]propanamido]acetamido}-3-(1H-imidazol-4-yl)propanoic acid

Asn Ala His Gly

2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-carbamoylpropanamido]propanamido]-3-(1H-imidazol-4-yl)propanamido]acetic acid

Asn Ala Pro Pro

(2S)-1-{[(2S)-1-[(2S)-2-[(2S)-2-amino-3-carbamoylpropanamido]propanoyl]pyrrolidin-2-yl]carbonyl}pyrrolidine-2-carboxylic acid

Asn Gly Ala His

(2S)-2-[(2S)-2-{2-[(2S)-2-amino-3-carbamoylpropanamido]acetamido}propanamido]-3-(1H-imidazol-4-yl)propanoic acid

Asn Gly His Ala

(2S)-2-[(2S)-2-{2-[(2S)-2-amino-3-carbamoylpropanamido]acetamido}-3-(1H-imidazol-4-yl)propanamido]propanoic acid

Asn His Ala Gly

2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-carbamoylpropanamido]-3-(1H-imidazol-4-yl)propanamido]propanamido]acetic acid

Asn His Gly Ala

(2S)-2-{2-[(2S)-2-[(2S)-2-amino-3-carbamoylpropanamido]-3-(1H-imidazol-4-yl)propanamido]acetamido}propanoic acid

Asn Pro Ala Pro

(2S)-1-[(2S)-2-{[(2S)-1-[(2S)-2-amino-3-carbamoylpropanoyl]pyrrolidin-2-yl]formamido}propanoyl]pyrrolidine-2-carboxylic acid

Asn Pro Pro Ala

(2S)-2-{[(2S)-1-{[(2S)-1-[(2S)-2-amino-3-carbamoylpropanoyl]pyrrolidin-2-yl]carbonyl}pyrrolidin-2-yl]formamido}propanoic acid

Pro Ala Asn Pro

(2S)-1-[(2S)-3-carbamoyl-2-[(2S)-2-[(2S)-pyrrolidin-2-ylformamido]propanamido]propanoyl]pyrrolidine-2-carboxylic acid

Pro Ala Pro Asn

(2S)-3-carbamoyl-2-{[(2S)-1-[(2S)-2-[(2S)-pyrrolidin-2-ylformamido]propanoyl]pyrrolidin-2-yl]formamido}propanoic acid

Tyr Cys Leu

Pro Gly Lys Pro

(2S)-1-[(2S)-6-amino-2-{2-[(2S)-pyrrolidin-2-ylformamido]acetamido}hexanoyl]pyrrolidine-2-carboxylic acid

Pro Gly Pro Lys

(2S)-6-amino-2-{[(2S)-1-{2-[(2S)-pyrrolidin-2-ylformamido]acetyl}pyrrolidin-2-yl]formamido}hexanoic acid

Pro Gly Pro Gln

(2S)-4-carbamoyl-2-{[(2S)-1-{2-[(2S)-pyrrolidin-2-ylformamido]acetyl}pyrrolidin-2-yl]formamido}butanoic acid

Pro Gly Gln Pro

(2S)-1-[(2S)-4-carbamoyl-2-{2-[(2S)-pyrrolidin-2-ylformamido]acetamido}butanoyl]pyrrolidine-2-carboxylic acid

Diethylpropion(metabolite V-glucuronide)

Pro Lys Gly Pro

(2S)-1-{2-[(2S)-6-amino-2-[(2S)-pyrrolidin-2-ylformamido]hexanamido]acetyl}pyrrolidine-2-carboxylic acid

Pro Lys Pro Gly

2-{[(2S)-1-[(2S)-6-amino-2-[(2S)-pyrrolidin-2-ylformamido]hexanoyl]pyrrolidin-2-yl]formamido}acetic acid

Pro Asn Ala Pro

(2S)-1-[(2S)-2-[(2S)-3-carbamoyl-2-[(2S)-pyrrolidin-2-ylformamido]propanamido]propanoyl]pyrrolidine-2-carboxylic acid

Pro Asn Pro Ala

(2S)-2-{[(2S)-1-[(2S)-3-carbamoyl-2-[(2S)-pyrrolidin-2-ylformamido]propanoyl]pyrrolidin-2-yl]formamido}propanoic acid

Pro Pro Ala Asn

(2S)-3-carbamoyl-2-[(2S)-2-{[(2S)-1-{[(2S)-pyrrolidin-2-yl]carbonyl}pyrrolidin-2-yl]formamido}propanamido]propanoic acid

Pro Pro Gly Lys

(2S)-6-amino-2-(2-{[(2S)-1-{[(2S)-pyrrolidin-2-yl]carbonyl}pyrrolidin-2-yl]formamido}acetamido)hexanoic acid

Pro Pro Gly Gln

(2S)-4-carbamoyl-2-(2-{[(2S)-1-{[(2S)-pyrrolidin-2-yl]carbonyl}pyrrolidin-2-yl]formamido}acetamido)butanoic acid

Pro Pro Lys Gly

2-[(2S)-6-amino-2-{[(2S)-1-{[(2S)-pyrrolidin-2-yl]carbonyl}pyrrolidin-2-yl]formamido}hexanamido]acetic acid

Pro Pro Asn Ala

(2S)-2-[(2S)-3-carbamoyl-2-{[(2S)-1-{[(2S)-pyrrolidin-2-yl]carbonyl}pyrrolidin-2-yl]formamido}propanamido]propanoic acid

Pro Pro Gln Gly

2-[(2S)-4-carbamoyl-2-{[(2S)-1-{[(2S)-pyrrolidin-2-yl]carbonyl}pyrrolidin-2-yl]formamido}butanamido]acetic acid

Pro Gln Gly Pro

(2S)-1-{2-[(2S)-4-carbamoyl-2-[(2S)-pyrrolidin-2-ylformamido]butanamido]acetyl}pyrrolidine-2-carboxylic acid

Pro Gln Pro Gly

2-{[(2S)-1-[(2S)-4-carbamoyl-2-[(2S)-pyrrolidin-2-ylformamido]butanoyl]pyrrolidin-2-yl]formamido}acetic acid

Ile Tyr Cys

Glu Leu His

Tyr Ile Cys

Gln Gly Gly His

(2S)-2-(2-{2-[(2S)-2-amino-4-carbamoylbutanamido]acetamido}acetamido)-3-(1H-imidazol-4-yl)propanoic acid

Gln Gly His Gly

2-[(2S)-2-{2-[(2S)-2-amino-4-carbamoylbutanamido]acetamido}-3-(1H-imidazol-4-yl)propanamido]acetic acid

Gln Gly Pro Pro

(2S)-1-{[(2S)-1-{2-[(2S)-2-amino-4-carbamoylbutanamido]acetyl}pyrrolidin-2-yl]carbonyl}pyrrolidine-2-carboxylic acid

Gln His Gly Gly

2-{2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-3-(1H-imidazol-4-yl)propanamido]acetamido}acetic acid

Cys Tyr Ile

Gln Pro Gly Pro

(2S)-1-(2-{[(2S)-1-[(2S)-2-amino-4-carbamoylbutanoyl]pyrrolidin-2-yl]formamido}acetyl)pyrrolidine-2-carboxylic acid

Gln Pro Pro Gly

2-{[(2S)-1-{[(2S)-1-[(2S)-2-amino-4-carbamoylbutanoyl]pyrrolidin-2-yl]carbonyl}pyrrolidin-2-yl]formamido}acetic acid

Met Phe Thr

Leu His Glu

His Leu Glu

Phe Thr Met

His Glu Leu

Met Thr Phe

Thr Met Phe

Leu Tyr Cys

Dibutanoyllecithin

Choline, hydroxide, dihydrogen phosphate, inner salt, ester with 1,2-dibutyrin, L-

C16H32NO8P (397.1865)

Dibutyroyl lecithin

3,5,9-Trioxa-4-phosphatridecan-1-aminium, 4-hydroxy-N,N,N-trimethyl-10-oxo-7-(1-oxobutoxy)-, inner salt, 4-oxide

C16H32NO8P (397.1865)

PC(O-9:0/O-1:0)[U]

3,5,9-Trioxa-4-phosphaoctadecan-1-aminium, 4-hydroxy-7-methoxy-N,N,N-trimethyl-, inner salt, 4-oxide

PC(9:0/0:0)

3,5,9-Trioxa-4-phosphaoctadecan-1-aminium, 4,7-dihydroxy-N,N,N-trimethyl-10-oxo-, inner salt, 4-oxide, (R)-

PC(9:0/0:0)[U]

3,5,9-Trioxa-4-phosphaoctadecan-1-aminium, 4,7-dihydroxy-N,N,N-trimethyl-10-oxo-, inner salt, 4-oxide

PC(0:0/9:0)[U]

3,5,8-Trioxa-4-phosphaheptadecan-1-aminium, 4-hydroxy-7-(hydroxymethyl)-N,N,N-trimethyl-9-oxo-, inner salt, 4-oxide

PE(12:0/0:0)

Dodecanoic acid, 3-[[(2-aminoethoxy)hydroxyphosphinyl]oxy]-2-hydroxypropyl ester, (R)-

(±)14(15)-EET-SI

N-(methylsulfonyl)-13-(3-pentyloxiranyl)-5Z,8Z,11Z-tridecatrienamide

C21H35NO4S (397.2287)

S32826

P-[[4-[(1-oxotetradecyl)amino]phenyl]methyl]-phosphonic acid

C21H36NO4P (397.2382)

PhS1P

(2S,3S,4R)-2-amino-3,4-dihydroxyoctadecyl dihydrogen phosphate

PHS-1-Phosphate

Phytosphingosine-1-P

Drotaverin

(1Z)-1-[(3,4-diethoxyphenyl)methylidene]-6,7-diethoxy-1,2,3,4-tetrahydroisoquinoline

A - Alimentary tract and metabolism > A03 - Drugs for functional gastrointestinal disorders > A03A - Drugs for functional gastrointestinal disorders > A03AD - Papaverine and derivatives C78272 - Agent Affecting Nervous System > C66880 - Anticholinergic Agent > C29704 - Antimuscarinic Agent D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents > D010276 - Parasympatholytics D002492 - Central Nervous System Depressants > D009294 - Narcotics > D053610 - Opiate Alkaloids D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents C78272 - Agent Affecting Nervous System > C29698 - Antispasmodic Agent D002491 - Central Nervous System Agents > D000700 - Analgesics D002317 - Cardiovascular Agents > D014665 - Vasodilator Agents

Ketanserinol

bisdeallyalmitrine

C20H21F2N7 (397.1826)

Tiaprost

C20H29O6S (397.1685)

PC 8:0

1,2-dibutyryl-sn-glycero-3-phosphocholine

C16H32NO8P (397.1865)

LPC 9:0

1-nonanoyl-sn-glycero-3-phosphocholine

LPE 12:0

Dodecanoic acid, 3-[[(2-aminoethoxy)hydroxyphosphinyl]oxy]-2-hydroxypropyl ester, (R)-

Bz-Arg-4-Abz-OH hydrochloride salt

C20H23N5O4 (397.175)

Zoloperone

A-443654

(2s)-1-(1h-Indol-3-Yl)-3-{[5-(3-Methyl-1h-Indazol-5-Yl)pyridin-3-Yl]oxy}propan-2-Amine

C24H23N5O (397.1903)

A-443654 is a pan-Akt inhibitor and has equal potency against Akt1, Akt2, or Akt3 within cells (Ki=160 pM)[1].

diperodon

C22H27N3O4 (397.2001)

C78272 - Agent Affecting Nervous System > C245 - Anesthetic Agent

1-[3-(9,9-dimethylfluoren-2-yl)phenyl]isoquinoline

C30H23N (397.183)

[(1S)-1-(5-Fluoro-3,4-dihydro-4-oxo-3-phenyl-2-quinazolinyl)propyl]carbamic acid 1,1-dimethylethyl ester

3-N-BOC-AMINO-1-[2-AMINO-1-(3-PHENOXY-PHENYL)-ETHYL]-PYRROLIDINE

C23H31N3O3 (397.2365)

4-(9H-fluoren-9-ylmethoxycarbonylamino)-2-[(2-methylpropan-2-yl)oxy]butanoic acid

CA-074 methyl ester

Methyl N-({(2s,3s)-3-[(Propylamino)carbonyl]oxiran-2-Yl}carbonyl)-L-Isoleucyl-L-Prolinate

C19H31N3O6 (397.2213)

3-(2,2-diphenylethyl)-5-(2-piperidin-1-ylethyl)-1,2,4-oxadiazole,hydrochloride

C23H28ClN3O (397.1921)

N-(4-Biphenylyl)-N-phenyl-4-biphenylamine

C30H23N (397.183)

Fmoc-sta-oh

H-His(Trt)-OH

H-D-His(Trt)-OH

octaverine

Diethylamino hydroxybenzoyl hexyl benzoate

4-[2,6-bis(2,4-dimethylphenyl)-1H-1,3,5-triazin-4-ylidene]-3-hydroxycyclohexa-2,5-dien-1-one

(-)-Butaclamol Hydrochloride

C25H32ClNO (397.2172)

1-[(2-methylpropan-2-yl)oxycarbonyl]-4-(4-phenylmethoxyphenyl)pyrrolidine-3-carboxylic acid

(+)-Butaclamol Hydrochloride

C25H32ClNO (397.2172)

Fmoc-D-Allo-Thr(tBu)-OH

4-(2-(BENZYL(METHYL)AMINO)ETHYL)-1,2-PHENYLENE BIS(2-METHYLPROPANOATE)

Fmoc-Thr(tBu)-OH

Sodium N-tetradecanoyl-L-phenlyalaninate

C23H36NNaO3 (397.2593)

2 6-bis[(4s 5s)-4-methyl-5-phenyl-2-oxa&

cobalt cyclohexanebutyrate

C20H34CoO4 (397.1789)

Fmoc-N-Me-Ser(tBu)-OH

4-(9H-fluoren-9-ylmethoxycarbonylamino)-3-[(2-methylpropan-2-yl)oxy]butanoic acid

FMOC-(3S,4S, 5S)-4-AMINO-3-HYDROXY-5-METHYL HEPTANOIC ACID

Fmoc-l-beta-homoserine(otbu)

Fmoc-Thr-OtBu

6,7-dimethoxy-1-(3,4,5-triethoxyphenyl)isoquinoline

2,6-bis((S)-4-benzyl-4,5-dihydrooxazol-2-yl)pyridine

N-([1,1-biphenyl]-4-yl)-[1,1:4,1-terphenyl]-4-amine

C30H23N (397.183)

Prochlorperazine Sulfoxide

C20H16ClD8N3OS (397.1831)

ETHYL 5-((7-ETHOXY-7-OXOHEPTYL)OXY)-4-METHOXY-2-NITROBENZOATE

2 6-BIS[(4R 5R)-4-METHYL-5-PHENYL-2-OXA&

Fmoc-Allo-Thr(tBu)-OH

manganese neodecanoate

C20H38MnO4 (397.215)

Butanoic acid, 3-(1,1-dimethylethoxy)-4-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-, (3S)

Fmoc-O-tert-butyl-D-threonine