Exact Mass: 380.12196
Exact Mass Matches: 380.12196
Found 500 metabolites which its exact mass value is equals to given mass value 380.12196,
within given mass tolerance error 0.05 dalton. Try search metabolite list with more accurate mass tolerance error
0.01 dalton.
Meticillin
C17H20N2O6S (380.10420200000004)
Meticillin is only found in individuals that have used or taken this drug. It is one of the penicillins which is resistant to penicillinase but susceptible to a penicillin-binding protein. It is inactivated by gastric acid so administered by injection. [PubChem]Like other beta-lactam antibiotics, meticillin acts by inhibiting the synthesis of bacterial cell walls. It inhibits cross-linkage between the linear peptidoglycan polymer chains that make up a major component of the cell wall of Gram-positive bacteria. It does this by binding to and competitively inhibiting the transpeptidase enzyme used by bacteria to cross-link the peptide (D-alanyl-alanine) used in peptidogylcan synthesis. J - Antiinfectives for systemic use > J01 - Antibacterials for systemic use > J01C - Beta-lactam antibacterials, penicillins > J01CF - Beta-lactamase resistant penicillins D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D047090 - beta-Lactams D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D010406 - Penicillins D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D007769 - Lactams C254 - Anti-Infective Agent > C258 - Antibiotic > C260 - Beta-Lactam Antibiotic
Diphyllin
Diphyllin is a lignan. Diphyllin is a natural product found in Haplophyllum alberti-regelii, Haplophyllum bucharicum, and other organisms with data available. Origin: Plant Diphyllin is an arylnaphthalene lignan isolated from Justicia procumbens and is a potent HIV-1 inhibitor with an IC50 of 0.38 μM. Diphyllin is active against vesicular stomatitis virus (VSV) and influenza virus[1]. Diphyllin is a vacuolar type H+-ATPase (V-ATPase) inhibitor with an IC50 value of 17 nM and inhibits lysosomal acidification in human osteoclasts[2]. Diphyllin inhibits NO production with an IC50 of 50 μM and has anticancer and anti-inflammatory activities[3]. Diphyllin is an arylnaphthalene lignan isolated from Justicia procumbens and is a potent HIV-1 inhibitor with an IC50 of 0.38 μM. Diphyllin is active against vesicular stomatitis virus (VSV) and influenza virus[1]. Diphyllin is a vacuolar type H+-ATPase (V-ATPase) inhibitor with an IC50 value of 17 nM and inhibits lysosomal acidification in human osteoclasts[2]. Diphyllin inhibits NO production with an IC50 of 50 μM and has anticancer and anti-inflammatory activities[3].
4-Ethyl-3-(p-hydroxyphenyl)-2,2-dimethyl-2H-1-benzopyran-7-ol diacetate
Chlorotrianisene
C23H21ClO3 (380.11791460000006)
G - Genito urinary system and sex hormones > G03 - Sex hormones and modulators of the genital system > G03C - Estrogens > G03CA - Natural and semisynthetic estrogens, plain D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones > D004967 - Estrogens C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C483 - Therapeutic Estrogen D000970 - Antineoplastic Agents
Upadacitinib
C17H19F3N6O (380.15723599999995)
L - Antineoplastic and immunomodulating agents > L04 - Immunosuppressants > L04A - Immunosuppressants > L04AA - Selective immunosuppressants D004791 - Enzyme Inhibitors > D047428 - Protein Kinase Inhibitors > D000075242 - Janus Kinase Inhibitors C471 - Enzyme Inhibitor > C1404 - Protein Kinase Inhibitor > C1967 - Tyrosine Kinase Inhibitor COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials D018501 - Antirheumatic Agents Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS
Rhodamine 123
D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents > D049408 - Luminescent Agents D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents > D012235 - Rhodamines D004396 - Coloring Agents > D005456 - Fluorescent Dyes
Rhodamine 123
C21H17ClN2O3 (380.09276420000003)
D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents > D049408 - Luminescent Agents D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents > D012235 - Rhodamines D004396 - Coloring Agents > D005456 - Fluorescent Dyes
8-Desoxygartanin
8-Desoxygartanin is a member of xanthones. 8-Desoxygartanin is a natural product found in Garcinia merguensis, Garcinia intermedia, and other organisms with data available. Isolated from Garcinia mangostana (mangosteen). 8-Desoxygartanin is found in fruits and purple mangosteen. 8-Desoxygartanin is found in fruits. 8-Desoxygartanin is isolated from Garcinia mangostana (mangosteen 8-Deoxygartanin, a prenylated xanthones from G. mangostana, is a selective inhibitor of butyrylcholinesterase (BChE)[1]. 8-Deoxygartanin exhibits antiplasmodial activity with an IC50 of 11.8 μM for the W2 strain of Plasmodium falciparum[2]. 8-Deoxygartanin inhibits NF-κB (p65) activation with an IC50 of 11.3 μM[3]. 8-Deoxygartanin, a prenylated xanthones from G. mangostana, is a selective inhibitor of butyrylcholinesterase (BChE)[1]. 8-Deoxygartanin exhibits antiplasmodial activity with an IC50 of 11.8 μM for the W2 strain of Plasmodium falciparum[2]. 8-Deoxygartanin inhibits NF-κB (p65) activation with an IC50 of 11.3 μM[3].
Gibberellin A86
Gibberellin A86 (GA86) belongs to the class of organic compounds known as C19-gibberellin 6-carboxylic acids. These are C19-gibberellins with a carboxyl group at the 6-position. Gibberellin A86 is found in fruits. Gibberellin A86 is a constituent of Prunus persica (peaches). Constituent of Prunus persica (peaches). Gibberellin A86 is found in many foods, some of which are peach, sweet cherry, sour cherry, and fruits.
Methyl helianthenoate A glucoside
Methyl helianthenoate A glucoside is found in root vegetables. Methyl helianthenoate A glucoside is a constituent of Helianthus tuberosus (Jerusalem artichoke). Constituent of Helianthus tuberosus (Jerusalem artichoke). Methyl helianthenoate A glucoside is found in root vegetables.
(E)-4-(3,7-Dimethyl-2,6-octadienyl)-1,3,5-trihydroxyxanthone
(E)-4-(3,7-Dimethyl-2,6-octadienyl)-1,3,5-trihydroxyxanthone is found in fruits. (E)-4-(3,7-Dimethyl-2,6-octadienyl)-1,3,5-trihydroxyxanthone is isolated from the root bark of Garcinia livingstonei (imbe). Isolated from the root bark of Garcinia livingstonei (imbe). (E)-4-(3,7-Dimethyl-2,6-octadienyl)-1,3,5-trihydroxyxanthone is found in fruits.
8-Oxodiacetoxyscirpenol
8-Oxodiacetoxyscirpenol is from Fusarium sporotrichioides. From Fusarium sporotrichioides
Mangostinone
Constituent of the pericarps of Garcinia mangostana (mangosteen). Mangostinone is found in fruits and purple mangosteen. Mangostinone is found in fruits. Mangostinone is a constituent of the pericarps of Garcinia mangostana (mangosteen).
(S)-Bitalin A 12-glucoside
(S)-Bitalin A 12-glucoside is found in herbs and spices. (S)-Bitalin A 12-glucoside is a constituent of Helichrysum italicum (curry plant). Constituent of Helichrysum italicum (curry plant). (S)-Bitalin A 12-glucoside is found in tea and herbs and spices.
Garcinone A
Garcinone A is found in fruits. Garcinone A is a constituent of Garcinia mangostana (mangosteen)
3-O-Methylglycyrol
3-O-Methylglycyrol is found in root vegetables. 3-O-Methylglycyrol is isolated from Glycyrrhiza species roots. Isolated from Glycyrrhiza subspecies roots. 3-O-Methylglycyrol is found in root vegetables.
6-Deoxy-gamma-mangostin
6-Deoxy-gamma-mangostin is found in fruits. 6-Deoxy-gamma-mangostin is isolated from Garcinia mangostana (mangosteen). Isolated from Garcinia mangostana (mangosteen). 6-Deoxy-gamma-mangostin is found in fruits.
Gibberellin A75
Gibberellin A75 (GA75) belongs to the class of organic compounds known as C19-gibberellin 6-carboxylic acids. These are C19-gibberellins with a carboxyl group at the 6-position. Gibberellin A75 is found in fats and oils. Gibberellin A75 is a constituent of seeds of Helianthus annuus (sunflower). Constituent of seeds of Helianthus annuus (sunflower). Gibberellin A75 is found in sunflower and fats and oils.
Chlorotrianisene
C23H21ClO3 (380.11791460000006)
Chlorotrianisene is only found in individuals that have used or taken this drug. It is a powerful synthetic, non-steroidal estrogen.Chlorotrianisene binds to the estrogen receptor on various estrogen receptor bearing cells. Target cells include cells in the female reproductive tract, the mammary gland, the hypothalamus, and the pituitary. Estrogens increase the hepatic synthesis of sex hormone binding globulin (SHBG), thyroid-binding globulin (TBG), and other serum proteins and suppress follicle-stimulating hormone (FSH) from the anterior pituitary. G - Genito urinary system and sex hormones > G03 - Sex hormones and modulators of the genital system > G03C - Estrogens > G03CA - Natural and semisynthetic estrogens, plain D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones > D004967 - Estrogens C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C483 - Therapeutic Estrogen D000970 - Antineoplastic Agents
N-(1-Deoxy-1-fructosyl)tryptophan
Fructose aminoacids are naturally occurring compounds derived from D-fructose and L-aminoacids. They are amadori products resulting from sugar-aminoacid interactions in food products, especially cooked foods [CCD] N-(1-Deoxy-1-fructosyl)tryptophan is classified as a Natural Food Constituent (code WA) in the DFC.
2-(4-Hydroxyphenyl)-3,6-dimethoxy-8,8-dimethyl-4H,8H-benzo[1,2-b:3,4-b']dipyran-4-one
2-(4-Hydroxyphenyl)-3,6-dimethoxy-8,8-dimethyl-4H,8H-benzo[1,2-b:3,4-b]dipyran-4-one is found in citrus. 2-(4-Hydroxyphenyl)-3,6-dimethoxy-8,8-dimethyl-4H,8H-benzo[1,2-b:3,4-b]dipyran-4-one is a constituent of the fruits of tangerine (Citrus reticulata cv. blanco). Constituent of the fruits of tangerine (Citrus reticulata cv. blanco). 2-(4-Hydroxyphenyl)-3,6-dimethoxy-8,8-dimethyl-4H,8H-benzo[1,2-b:3,4-b]dipyran-4-one is found in citrus.
Bmn-673 8R,9S
C19H14F2N6O (380.11970979999995)
N-(5-(((5-(1,1-Dimethylethyl)-2-oxazolyl)methyl)thio)-2-thiazolyl)-4-piperidinecarboxamide
C17H24N4O2S2 (380.13406039999995)
C274 - Antineoplastic Agent > C2189 - Signal Transduction Inhibitor > C129824 - Antineoplastic Protein Inhibitor C471 - Enzyme Inhibitor > C1404 - Protein Kinase Inhibitor > C2185 - Cyclin-Dependent Kinase Inhibitor C471 - Enzyme Inhibitor > C129825 - Antineoplastic Enzyme Inhibitor C274 - Antineoplastic Agent > C163758 - Targeted Therapy Agent
Amosulalol
C78272 - Agent Affecting Nervous System > C29747 - Adrenergic Agent > C72900 - Adrenergic Antagonist D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents > D018674 - Adrenergic Antagonists D002317 - Cardiovascular Agents > D000959 - Antihypertensive Agents
Egtazic acid
D064449 - Sequestering Agents > D002614 - Chelating Agents > D065096 - Calcium Chelating Agents D020011 - Protective Agents > D000931 - Antidotes
4-[[2-(2-Acetylsulfanylethyl)-4,6,7-trimethyl-2,3-dihydro-1-benzofuran-5-yl]oxy]-4-oxobutanoic acid
1,4-Diamino-2,3-dicyano-1,4-bis(o-aminophenylmercapto)butadiene
C18H16N6S2 (380.08778159999997)
N-((2-(2-Fluoroethoxy)phenyl)methyl)-N-(4-phenoxy-3-pyridinyl)acetamide
Upadacitinib
C17H19F3N6O (380.15723599999995)
Varespladib
C78272 - Agent Affecting Nervous System > C241 - Analgesic Agent > C2198 - Nonnarcotic Analgesic COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS Varespladib (LY315920) is a potent and selective group IIA, secretory phospholipase A2 (sPLA2) inhibitor with an IC50 of 9 nM. Varespladib exhibits the significant inhibitory effect on sPLA2 activity in serum from various species including rat, rabbit, guinea pig and human with IC50s of 8.1 nM, 5.0 nM, 3.2 nM and 6.2 nM, respectively[1].
Vellokaempferol 3,4-dimethyl ether
Ovalichromene A
3,4-Methylenedioxy-2-methoxy-6,6-dimethlchromeno-[2,3:4,3]-beta-hydroxychalcone
Indicanine A
[3aR-(3aR*,4S*,5R*,6E,10S*,11R*,11aS*)]-2,3,3a,4,5,8,9,10,11,11a-Decahydro-5,10,11-trihydroxy-6,10-dimethyl-3-methylene-2,9-dioxocyclodeca[b]furan-4-yl ester 2-methyl-2-propenoic acid
1,3,5-Trihydroxy-4,8-di(3-methylbut-2-enyl)-xanthone
Robustic acid
1,3,7-Trihydroxy-2,4-di(3-methylbut-2-enyl)xanthone
Muxiangrin II
Millettocalyxin B
Multijuginol
7-Methoxypraecansone B
A member of the class of chalcones that is chalcone substituted by methoxy groups at positions 2, 6 and 7 and a dimethylpyrano ring substituted across positions 3 and 4. Isolated from Pongamia pinnata, it has been found to induce quinone reductase.
7-Prenyloxy-8-methoxy-3,4-methylenedioxyisoflavone
Praecanson A
A member of the class of chalcones that is chalcone substituted by methoxy groups at positions 2, 6 and 9 and a dimethylpyrano ring substituted across positions 3 and 4.
4-Hydroxy-3,6-dimethoxy-6,6-dimethylpyrano[2,3:7,8]flavone
CP-457677
CONFIDENCE standard compound; INTERNAL_ID 1093; DATASET 20200303_ENTACT_RP_MIX499; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8647; ORIGINAL_PRECURSOR_SCAN_NO 8646 CONFIDENCE standard compound; INTERNAL_ID 1093; DATASET 20200303_ENTACT_RP_MIX499; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8673; ORIGINAL_PRECURSOR_SCAN_NO 8672 CONFIDENCE standard compound; INTERNAL_ID 1093; DATASET 20200303_ENTACT_RP_MIX499; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8683; ORIGINAL_PRECURSOR_SCAN_NO 8681 CONFIDENCE standard compound; INTERNAL_ID 1093; DATASET 20200303_ENTACT_RP_MIX499; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8694; ORIGINAL_PRECURSOR_SCAN_NO 8693 CONFIDENCE standard compound; INTERNAL_ID 1093; DATASET 20200303_ENTACT_RP_MIX503; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8711; ORIGINAL_PRECURSOR_SCAN_NO 8708 CONFIDENCE standard compound; INTERNAL_ID 1093; DATASET 20200303_ENTACT_RP_MIX503; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8699; ORIGINAL_PRECURSOR_SCAN_NO 8697
7-{[(2E)-3,7-Dimethyl-2,6-octadien-1-yl]oxy}-1,3-dihydroxy-9H-xanthen-9-one
3,15-Diacetyldeoxynivalenol
D009676 - Noxae > D011042 - Poisons > D014255 - Trichothecenes D009676 - Noxae > D011042 - Poisons > D009183 - Mycotoxins CONFIDENCE isolated standard
3,4-diacetoxy-5-(benzoyloxymethyl)-5,6-epoxycyclohexan-1,2-diol
4-(1,3-benzodioxol-5-yl)-1-hydroxy-6,7-dimethoxy-1H-benzo[f]isobenzofuran-3-one
3,7,4-trihydroxy-4-(2,4-dihydroxy-6-methylphenyl)flavan
(+)-howiinol A|(+)-howiionol A|(1R,2R)-2-hydroxy-2-((2R,3S)-3-hydroxy-6-oxo-3,6-dihydro-2H-pyran-2-yl)-1-phenylethyl cinnamate|howiinol A
1,3,7-trihydroxy-2,4-diisoprenylxanthone
A member of the class of xanthones that is 9H-xanthene substituted by hydroxy group at positions 1, 3 and 7, an oxo group at position 9 and prenyl groups at positions 2 and 4. It has been isolated from the stems of Cratoxylum cochinchinense
1,2-O-Ethylidene,4,6-di-Ac,3-benzyl-alpha-D-Pyranose-Allose
2,3,4-Tri-O-Ac,1-O-benzoyl-alpha-D-Pyranose-Lyxose
3beta,13-diacetoxy-1alpha-hydroperoxygermacra-4E,9Z,7(11)-triene-12,6alpha-olide
6-acetyl-2,2-dimethylchromene-8-O-beta-D-glucopyranoside
8alpha-acetoxy-4alpha,5alpha-epoxyjalcaguaianolide 13-O-acetate
3-[2-(1,3-Benzodioxole-5-yl)benzofuran-5-yl]-1-propanol 2-methylbutyrate
1-(2,2-Dimethyl-5-methoxy-2H-1-benzopyran-6-yl)-3-(1,3-benzodioxol-5-yl)propane-1,3-dione
[3aR-(3aR*,4S*,5R*,6E,10S*,11R*,11aS*)]-2,3,3a,4,5,8,9,10,11,11a-Decahydro-5,10,11-trihydroxy-6,10-dimethyl-3-methylene-2,9-dioxocyclodeca[b]furan-4-yl ester 2-methyl-2-propenoic acid
(9aS)-3-Acetyl-6-((S)-3,5-dimethyl-hepta-1,3t-dien-t-yl)-9a-methyl-9aH-furo[3,2-g]isochromen-2,9-dion|(9aS)-3-acetyl-6-((S)-3,5-dimethyl-hepta-1,3t-dien-t-yl)-9a-methyl-9aH-furo[3,2-g]isochromene-2,9-dione|Rotiorin
1,3,5-trihydroxy-2-(2,2-dimethyl-4-isopropenyl)cyclopentanylxanthone|6-deoxy-5-O-demethylpaxanthonin
(5bR,10bR)-5b,10b-dihydro-8-hydroxy-5-methoxy-2,2-dimethyl-2H,11H-benzo[4,5]furo[2,3-d]pyrano[3,2-g]chromene-7-carbaldehyde|gangetial
2-Methyl-3-(hydroxymethyl)-3,4-dihydro-4-[[2-(3,4-dihydroxyphenyl)ethyloxy]carbonylmethyl]-2H-pyran-5-carboxylic acid methyl ester
(1R,6S,7R,8S,10R)-8,14-diacetoxy-1(10)-epoxy-15-hydroxygermacra-1(10),4,11(13)-trien-6,12-olide
1,7-dihydroxy-2(Z)-(4-hydroxybenzylidene)-6-(3-methylbut-2-enyl)-indan-1-carboxylic acid methyl ester|phomoindene A
(2E,8E,10E,12R)-tridecatriene-4,6-diyne-1,12,13-triol-1-O-beta-D-glucopyranoside
2-carbomethoxy-1,4-naphthohydroquinone-4-O-beta-D-glucopyranoside|rubinaphthin A methyl ester
butyl 7-{(benzoyloxy)methyl}-3,8-dihydroxy-2,6-dioxabicyclo[3.2.1]octane-3-carboxylate|decurrenside E
5,6-Dihydro-hypothemycin|5,6-dihydrohypothemycin|7,8-dihydrohypothemycin|dihydrohypothemycin
3beta,9beta-diacetoxy-1beta-hydroperoxy-6beta,7alphaH-germacra-4,10(14),11(13)-trien-12,6alpha-olide
(2S)-2?,5,7-trihydroxy-6-prenyl-furo[2?,3?:4?,5?]flavanone|cudraflavanone E
4,5,7-trihydroxy-6-(2-hydroxy-3-methylbut-3-enyl)-2-styrylchromone|platachromone C
4,5,7-trihydroxy-8-(2-hydroxy-3-methylbut-3-enyl)-2-styrylchromone|platachromone D
(4S,5R)-4-hydroxy-5-(8-{[3,4,5-trihydroxy-6-(hydroxymethyl)-tetrahydro-2H-pyran-2-yl]oxy}octa-2,4,6-triyn-1-yl)dihydrofuran-2(3H)-one|4beta-hydroxy-3,4-dihydrovernoniyne-8-O-beta-glucoside
(4S,5R)-5-(8-hydroxyocta-2,4,6-triyn-1-yl)-4-{[3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}dihydrofuran-2(3H)-one|8-hydroxy-3,4-dihydrovernoniyne-4-O-beta-glucoside
3beta,13-diacetoxy-1beta-hydroxygermacra-4E,7(11),10(14)-triene-12,6alpha-olide
1,2-bis(4-hydroxy-3,5-dimethoxyphenyl)propane-1,3-diol
1,2-Di-O-acyl-3-O-(6-O-acyl-beta-D-galactopyranosyl)-sn-glycerol
C15H24O11 (380.13185539999995)
(1S*,2R*,5R*,6R*,7S*,8R*,9R*10S*)-2,9-diacetoxy-8,10-dihydroxyguaia-3,11(13)-diene-6,12-olide
10-(3,4-dimethoxyphenyl)-6-hydroxyfuro[3,4:6,7]naphtho[1,2-d]-1,3-dioxol-9(7h)-one
C2-alpha-D-mannosylpyranosyl-L-Nalpha-methyltryptophan
1??,3??,15-Trihydroxy-3,10-epoxy-8??-O-methacryloyl-4,11-germacradiene,6??,12-olide
BIBB 515
BIBB 515 is a potent, selective and orally active 2,3-oxidosqualene cyclase (OSC) inhibitor with ED50 values of 0.2-0.5 mg/kg and 0.36-33.3 mg/kg in rats and mice (1-5 hours), respectively. BIBB 515 exerts lipid-lowering effect mainly by inhibiting the production of low-density lipoprotein (LDL)[1].
U-0126
C18H16N6S2 (380.08778159999997)
U0126 is a potent, non-ATP competitive and selective MEK1 and MEK2 inhibitor, with IC50s of 72 nM and 58 nM, respectively. U0126 is an autophagy and mitophagy inhibitor[1][2][3][4].
MLS001401364-01!Cilastatin sodium
C16H25N2NaO5S (380.13818000000003)
methyl 4-(4,6-dihydroxy-5-methoxy-2,5-dimethyl-3-oxocyclohexen-1-yl)oxy-2-hydroxy-3,6-dimethylbenzoate
methyl 2-(4,5-dihydroxy-6-methoxy-3,6-dimethyl-2-oxocyclohex-3-en-1-yl)oxy-4-hydroxy-3,6-dimethylbenzoate
methyl 2-(4,5-dihydroxy-6-methoxy-3,6-dimethyl-2-oxocyclohex-3-en-1-yl)oxy-4-hydroxy-3,6-dimethylbenzoate
methyl 4-(4,6-dihydroxy-5-methoxy-2,5-dimethyl-3-oxocyclohexen-1-yl)oxy-2-hydroxy-3,6-dimethylbenzoate
methyl 2-(4,5-dihydroxy-6-methoxy-3,6-dimethyl-2-oxocyclohex-3-en-1-yl)oxy-4-hydroxy-3,6-dimethylbenzoate [IIN-based on: CCMSLIB00000848087]
methyl 2-(4,5-dihydroxy-6-methoxy-3,6-dimethyl-2-oxocyclohex-3-en-1-yl)oxy-4-hydroxy-3,6-dimethylbenzoate [IIN-based: Match]
Ala Cys Gly Met
Ala Cys Met Gly
Ala Cys Ser Thr
Ala Cys Thr Ser
Ala Gly Cys Met
Ala Gly Met Cys
Ala Met Cys Gly
Ala Met Gly Cys
Ala Ser Cys Thr
Ala Ser Thr Cys
Ala Thr Cys Ser
Ala Thr Ser Cys
Cys Ala Gly Met
Cys Ala Met Gly
Cys Ala Ser Thr
Cys Ala Thr Ser
Cys Cys Gly Val
Cys Cys Val Gly
Cys Asp Gly Ser
Cys Asp Ser Gly
Cys Gly Ala Met
Cys Gly Cys Val
Cys Gly Asp Ser
Cys Gly Met Ala
Cys Gly Ser Asp
Cys Gly Thr Thr
Cys Gly Val Cys
Cys Met Ala Gly
Cys Met Gly Ala
Cys Ser Ala Thr
Cys Ser Asp Gly
Cys Ser Gly Asp
Cys Ser Thr Ala
Cys Thr Ala Ser
Cys Thr Gly Thr
Cys Thr Ser Ala
Cys Thr Thr Gly
Cys Val Cys Gly
Cys Val Gly Cys
Asp Cys Gly Ser
Asp Cys Ser Gly
Asp Gly Cys Ser
Asp Gly Ser Cys
Asp Ser Cys Gly
Asp Ser Gly Cys
Gly Ala Cys Met
Gly Ala Met Cys
Gly Cys Ala Met
Gly Cys Cys Val
Gly Cys Asp Ser
Gly Cys Met Ala
Gly Cys Ser Asp
Gly Cys Thr Thr
Gly Cys Val Cys
Gly Asp Cys Ser
Gly Asp Ser Cys
Gly Met Ala Cys
Gly Met Cys Ala
Gly Met Ser Ser
Gly Ser Cys Asp
Gly Ser Asp Cys
Gly Ser Met Ser
Gly Ser Ser Met
Gly Thr Cys Thr
Gly Thr Thr Cys
Gly Val Cys Cys
Met Ala Cys Gly
Met Ala Gly Cys
Met Cys Ala Gly
Met Cys Gly Ala
Met Gly Ala Cys
Met Gly Cys Ala
Met Gly Ser Ser
Met Ser Gly Ser
Met Ser Ser Gly
Ser Ala Cys Thr
Ser Ala Thr Cys
Ser Cys Ala Thr
Ser Cys Asp Gly
Ser Cys Gly Asp
Ser Cys Thr Ala
Ser Asp Cys Gly
Ser Asp Gly Cys
Ser Gly Cys Asp
Ser Gly Asp Cys
Ser Gly Met Ser
Ser Gly Ser Met
Ser Met Gly Ser
Ser Met Ser Gly
Ser Ser Gly Met
Ser Ser Met Gly
Ser Ser Ser Thr
C13H24N4O9 (380.15432139999996)
Ser Ser Thr Ser
C13H24N4O9 (380.15432139999996)
Ser Thr Ala Cys
Ser Thr Cys Ala
Ser Thr Ser Ser
C13H24N4O9 (380.15432139999996)
Thr Ala Cys Ser
Thr Ala Ser Cys
Thr Cys Ala Ser
Thr Cys Gly Thr
Thr Cys Ser Ala
Thr Cys Thr Gly
Thr Gly Cys Thr
Thr Gly Thr Cys
Thr Ser Ala Cys
Thr Ser Cys Ala
Thr Ser Ser Ser
C13H24N4O9 (380.15432139999996)
Thr Thr Cys Gly
Thr Thr Gly Cys
Val Cys Cys Gly
Val Cys Gly Cys
Val Gly Cys Cys
Gibberellin A75
8-Oxodiacetoxyscirpenol
(S)-Bitalin A 12-glucoside
Gibberellin A86
Methyl helianthenoate A glucoside
4'-Hydroxy-3,6-dimethoxy-6'',6''-dimethylpyrano[2,3:7,8]flavone
Methyl 2-[(4,5-dihydroxy-6-methoxy-3,6-dimethyl-2-oxo-3-cyclohexen-1-yl)oxy]-4-hydroxy-3,6-dimethylbenzoate
5-[6-(8-Fluoro-2-naphthyl)-2-oxo-1,2-dihydro-3-pyridinyl]-5-isopr opyl-1,3-oxazolidine-2,4-dione
Furo[3,4:6,7]naphtho[2,3-d]-1,3-dioxol-6(8H)- one,5-(3,4-dimethoxyphenyl)-9-hydroxy-
Methyl 4-acetoxy-7-(benzyloxy)-6-methoxy-2-naphthoate
(R)-2-(PIPERIDIN-3-YL)ISOINDOLINE-1,3-DIONE (2S,3S)-2,3-DIHYDROXYSUCCINATE
1H-1,4-Diazepine,hexahydro-1,4-bis(phenylsulfonyl)-
C17H20N2O4S2 (380.08644400000003)
(R)-3-((1-METHYLPYRROLIDIN-2-YL)METHYL)-5-(2-(PHENYLSULFONYL)VINYL)-1H-INDOLE
2-aminophthalylhydrazido-n-acetyl-b-d-glucosaminide
(methylcyclopentadienyl)(1,5-cyclooctadiene)iridium(i)
[4-(4-chloro-phenyl)-piperazin-1-yl]-naphthalen-2-yl-acetic acid
(4-(TRIPHENYLSILYL)PHENYL)BORONIC ACID
C24H21BO2Si (380.14037959999996)
N-tert-butyl-N-[2-[(5-chloro-1,3-benzoxazol-2-yl)-(3-oxobutyl)amino]ethyl]carbamate
C18H23ClN3O4 (380.13770080000006)
1-(2-AMINO-PHENYL)-PIPERIDINE-3-CARBOXYLICACIDETHYLESTER
C20H20N4O4 (380.14844800000003)
XRP44X
XRP44X inhibits Ras-induced transcription activation with the IC50 of 10 nM. XRP44X inhibits activation of the Ras-Erk-1/2 pathway by FGF-2[1]. XRP44X is an inhibitor of Ras/Erk activation of Elk3 that also affects microtubules[2].
CHLORO(1,5-CYCLOOCTADIENE)(PENTAMETHYLCYCLOPENTADIENYL)RUTHENIUM
1H-1,4-Diazepine, 1-[(4-chlorophenyl)sulfonyl]-4-(4,6-dimethyl-2-pyrimidinyl)hexahydro- (9CI)
C17H21ClN4O2S (380.10736760000003)
1H-Indole,1-[[[4-ethyl-5-(2-furanyl)-4H-1,2,4-triazol-3-yl]thio]acetyl]-2,3-dimethyl-(9CI)
Biclotymol
C254 - Anti-Infective Agent > C28394 - Topical Anti-Infective Agent
GTS-21
C19H22Cl2N2O2 (380.10582519999997)
GTS-21 dihydrochloride is a selective alpha7 nicotinic acetylcholine receptor (α7-nAChR) agonist with anti?inflammatory and cognition?enhancing activities. GTS-21 dihydrochloride is also a α4β2 (Ki=20 nM for humanα4β2) and 5-HT3A receptor (IC50=3.1 μM) antagonist[1][2].
1-(2,4,6-TRIISOPROPYLBENZENESULFONYL)-3-NITRO-1H-1,2,4-TRIAZOLE
BMN 673
C19H14F2N6O (380.11970979999995)
D000970 - Antineoplastic Agents > D000067856 - Poly(ADP-ribose) Polymerase Inhibitors D004791 - Enzyme Inhibitors
2-Methyl-2-propanyl 4-(5-bromo-1H-pyrrolo[2,3-b]pyridin-4-yl)-1-p iperazinecarboxylate
N-(6-isoquinolin-5-ylnaphthalen-2-yl)thiophene-2-carboxamide
Talazoparib
C19H14F2N6O (380.11970979999995)
L - Antineoplastic and immunomodulating agents > L01 - Antineoplastic agents > L01X - Other antineoplastic agents > L01XK - Poly (adp-ribose) polymerase (parp) inhibitors C274 - Antineoplastic Agent > C163758 - Targeted Therapy Agent > C62554 - Poly (ADP-Ribose) Polymerase Inhibitor D000970 - Antineoplastic Agents > D000067856 - Poly(ADP-ribose) Polymerase Inhibitors D004791 - Enzyme Inhibitors C471 - Enzyme Inhibitor
2-benzofuran-1,3-dione,2-ethyl-2-(hydroxymethyl)propane-1,3-diol,furan-2,5-dione
trabodenoson
C78283 - Agent Affecting Organs of Special Senses > C29705 - Anti-glaucoma Agent C78274 - Agent Affecting Cardiovascular System > C29707 - Vasodilating Agent Trabodenoson (INO-8875), an adenosine mimetic, is a highly selective Adenosine A1 receptor agonist. Trabodenoson (INO-8875) is used in the study for Primary Open-Angle Glaucoma[1].
3(S)-BOC-AMINO-2,3-DIHYDRO-4-OXO-1,5-BENZOTHIAZEPINE-5(2H)-ACETIC ACID ETHYL ESTER
3-[ethyl[4-[(6-nitrobenzothiazol-2-yl)azo]phenyl]amino]propiononitrile
2-[(2-Aminoethoxy)methyl]-4-(2-chlorophenyl)-5-(methoxycarbonyl)-6-methyl-1,4-dihydro-3-pyridinecarboxylic acid
C18H21ClN2O5 (380.11389260000004)
(1R,2R,N1E,N2E)-N1,N2-bis(2-nitrobenzylidene)cyclohexane-1,2-diamine
C20H20N4O4 (380.14844800000003)
Ethanol, 2-[2-(2-phenoxyethoxy)ethoxy]-, 4-methylbenzenesulfonate
bis(ethyl acetoacetato-O1,O3)[propane-1,3-diolato(2-)-O,O]titanium
4-PHENYL-5-(2-PHENYLQUINOLIN-4-YL)-4H-1,2,4-TRIAZOLE-3-THIOL
diethyl 3,6-diphenyl-1,2,4,5-tetrazine-1,2-dicarboxylate
C20H20N4O4 (380.14844800000003)
1,1-Diphenyl-4,4-bipyridinium dichloride
C22H18Cl2N2 (380.08469679999996)
3-(1H-2-INDOLYL)-4-(4-METHOXYPHENYL)-1-METHYL-1H-2-QUINOLINONE
U0126
C18H16N6S2 (380.08778159999997)
C274 - Antineoplastic Agent > C163758 - Targeted Therapy Agent > C2149 - Mitogen-Activated Protein Kinase Inhibitor C471 - Enzyme Inhibitor > C1404 - Protein Kinase Inhibitor > C61074 - Serine/Threonine Kinase Inhibitor D004791 - Enzyme Inhibitors U0126 is a potent, non-ATP competitive and selective MEK1 and MEK2 inhibitor, with IC50s of 72 nM and 58 nM, respectively. U0126 is an autophagy and mitophagy inhibitor[1][2][3][4].
rubinaphthin A methyl ester
A member of the class of naphthols that is naphthalen-1-ol substituted by a beta-D-glucopyranosyloxy residue at position 4 and a methoxycarbonyl group at position 2. It has been isolated from the roots of Rubia yunnanensis.
N-[4-[(2,6-dimethoxy-4-pyrimidinyl)sulfamoyl]phenyl]butanamide
C16H20N4O5S (380.11543500000005)
5-[2-(2,6-Dioxocyclohexylidene)hydrazinyl]-3-methylthiophene-2,4-dicarboxylic acid diethyl ester
C17H20N2O6S (380.10420200000004)
3-Pyridinecarboxamide, 2-(4-fluorophenoxy)-N-((4-(1-hydroxy-1-methylethyl)phenyl)methyl)-
4-(3-{[5-(Trifluoromethyl)pyridin-2-Yl]oxy}benzyl)piperidine-1-Carboxylic Acid
Egtazic acid
D064449 - Sequestering Agents > D002614 - Chelating Agents > D065096 - Calcium Chelating Agents D020011 - Protective Agents > D000931 - Antidotes
Cilastatin Sodium
C16H25N2NaO5S (380.13818000000003)
D004791 - Enzyme Inhibitors > D011480 - Protease Inhibitors C471 - Enzyme Inhibitor > C783 - Protease Inhibitor
Varespladib
C78272 - Agent Affecting Nervous System > C241 - Analgesic Agent > C2198 - Nonnarcotic Analgesic COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS Varespladib (LY315920) is a potent and selective group IIA, secretory phospholipase A2 (sPLA2) inhibitor with an IC50 of 9 nM. Varespladib exhibits the significant inhibitory effect on sPLA2 activity in serum from various species including rat, rabbit, guinea pig and human with IC50s of 8.1 nM, 5.0 nM, 3.2 nM and 6.2 nM, respectively[1].
Amosulalol
C78272 - Agent Affecting Nervous System > C29747 - Adrenergic Agent > C72900 - Adrenergic Antagonist D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents > D018674 - Adrenergic Antagonists D002317 - Cardiovascular Agents > D000959 - Antihypertensive Agents
4,5,7,12-Tetrahydroxy-11-methyl-6-methylidene-16-oxo-15-oxapentacyclo[9.3.2.15,8.01,10.02,8]heptadecane-9-carboxylic acid
5,7,12,13-Tetrahydroxy-11-methyl-6-methylidene-16-oxo-15-oxapentacyclo[9.3.2.15,8.01,10.02,8]heptadecane-9-carboxylic acid
8-Desmethylnovobiocic acid(1-)
An organic anion obtained by selective deprotonation of the 4-hydroxy group on the chromene ring of 8-desmethylnovobiocic acid.
[oxido-[(6E)-3,7,11-trimethyldodeca-1,6,10-trien-3-yl]oxyphosphoryl] hydrogen phosphate
C15H26O7P2-2 (380.11537059999995)
phosphono [(2E,4E,6E)-3,7,11-trimethyldodeca-2,4,6,10-tetraenyl] hydrogen phosphate
C15H26O7P2 (380.11537059999995)
3-(Benzenesulfonyl)-3-(4-methoxyphenyl)-1-phenyl-1-propanone
C22H20O4S (380.10822400000006)
4,6-bis(1-imidazolyl)-N,N-diphenyl-1,3,5-triazin-2-amine
N-(3,4-dimethoxyphenyl)-7-methoxy-4,5-dihydrobenzo[g][1,2]benzoxazole-3-carboxamide
N-[1-[(4-fluorophenyl)methyl]-3,5-dimethyl-4-pyrazolyl]-5-(2-furanyl)-3-isoxazolecarboxamide
2-[4-(Difluoromethylthio)anilino]benzoic acid [2-(dimethylamino)-2-oxoethyl] ester
3-[2-(3-Carboxy-acryloylamino)-biphenyl-2-ylcarbamoyl]-acrylic acid
2-(4-Anilinophenoxy)acetic acid [2-(2-furanylmethylamino)-2-oxoethyl] ester
1-(1-Naphthalenyl)-3-[[2-(2-nitrophenoxy)-1-oxoethyl]amino]urea
N-[1-(2-methylpropyl)-3-pyrazolo[3,4-b]quinolinyl]benzenesulfonamide
N-(3-methoxyphenyl)-1,3-dioxo-2-(2-oxolanylmethyl)-5-isoindolecarboxamide
4-[3-(2,4-dioxo-1H-thieno[3,2-d]pyrimidin-3-yl)-1-oxopropyl]-1-piperazinecarboxylic acid ethyl ester
C16H20N4O5S (380.11543500000005)
1-[5-(5-chloro-2-methylphenyl)-2-furanyl]-N-[4-(4-morpholinyl)phenyl]methanimine
Cyclopropanecarboxylic acid [5-(6-amino-5-cyano-3-methyl-2,4-dihydropyrano[2,3-c]pyrazol-4-yl)-2-ethoxyphenyl] ester
C20H20N4O4 (380.14844800000003)
(3aR,6aS)-3-(3,4-dimethoxyphenyl)-5-(2,4-dimethylphenyl)-3a,6a-dihydropyrrolo[3,4-d]isoxazole-4,6-dione
Ethyl {2-[(4-methylphenyl)amino]-1,3-thiazol-4-yl}(phenylhydrazono)acetate
(6-Methoxy-2-naphthalenyl)-[1-[(2-methyl-5-thiazolyl)methyl]-3-piperidinyl]methanone
[5-[(3,4-Difluorophenoxy)methyl]-3-isoxazolyl]-(3-propoxy-1-piperidinyl)methanone
C19H22F2N2O4 (380.15475560000004)
N-(1,3-benzodioxol-5-yl)-2-[ethyl-[(4-oxo-1H-quinazolin-2-yl)methyl]amino]acetamide
C20H20N4O4 (380.14844800000003)
4-[(2-Cyano-1-oxoethyl)amino]benzoic acid [2-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-oxoethyl] ester
2-[2-methoxy-4-[(E)-2-(8-nitroquinolin-2-yl)ethenyl]phenoxy]acetic acid
3-(Benzyloxy)-4-(trimethylsilyl)pyridin-2-yl dimethylsulfamate
methyl 2-[4-ethyl-2-methoxy-5-oxo-2-(9H-pyrido[3,4-b]indol-1-yl)furan-3-yl]acetate
Methyl (9R,12R,21S)-15,20-dioxo-19-oxa-8,16-diazahexacyclo[10.6.4.01,9.02,7.09,21.012,16]docosa-2,4,6,13-tetraene-8-carboxylate
sodium 3-aminopropyl 2-acetamido-2-deoxy-alpha-D-glucose-1-phosphate
1-(3,4-dimethylphenyl)-6-hydroxy-5-[(Z)-[(4-methoxyphenyl)hydrazinylidene]methyl]pyrimidine-2,4-dione
C20H20N4O4 (380.14844800000003)
5,8-Dihydroxy-2-(1-hydroxy-3-methoxy-4-oxocyclohexyl)-3,7-dimethoxychromen-4-one
2-(4-(4-Nitrophenyl)butan-2-ylamino)-1-(4-methoxyphenyl)ethanol Hydrochloride
1-(4-Chlorophenyl)-2-[4-methyl-6-(2-phenylethylamino)pyrimidin-2-yl]guanidine
(3S)-5-Bromo-3-(tert-butyldimethylsilyloxy)-1-pivaloyloxypentane
C16H33BrO3Si (380.13822079999994)
methicillin
C17H20N2O6S (380.10420200000004)
J - Antiinfectives for systemic use > J01 - Antibacterials for systemic use > J01C - Beta-lactam antibacterials, penicillins > J01CF - Beta-lactamase resistant penicillins D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D047090 - beta-Lactams D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D010406 - Penicillins D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D007769 - Lactams C254 - Anti-Infective Agent > C258 - Antibiotic > C260 - Beta-Lactam Antibiotic A penicillin compound having a (6R)-2,6-dimethoxybenzamido substituent.
SNS-032 (BMS-387032)
C17H24N4O2S2 (380.13406039999995)
C274 - Antineoplastic Agent > C2189 - Signal Transduction Inhibitor > C129824 - Antineoplastic Protein Inhibitor C471 - Enzyme Inhibitor > C1404 - Protein Kinase Inhibitor > C2185 - Cyclin-Dependent Kinase Inhibitor C471 - Enzyme Inhibitor > C129825 - Antineoplastic Enzyme Inhibitor C274 - Antineoplastic Agent > C163758 - Targeted Therapy Agent
IMB-808
IMB-808 is a potent LXRα/β dual agonist with EC50 values of 0.53 μM and 0.15 μM (0.15 μM, using GAL4-pGL4-luc reporter plasmid) for LXRβ and LXRα, respectively. IMB-808 promotes expression of genes related to reverse cholesterol transport (ABCA1 and ABCG1). IMB-808 can be used as a promising agent for the prospective treatment of atherosclerosis research[1].
Tulrampator
Tulrampator (S-47445) is an orally active selective AMPA receptor modulator. Tulrampator possesses procognitive, enhancing synaptic plasticity, anti-depressant-anxiolytic-like, procognitive and potential neuroprotective properties. Tulrampator can be used for research of alzheimer’s disease and in major depressive disorder[1][2][3].