Rhodamine 123 (BioDeep_00000017063)

   

Volatile Flavor Compounds


代谢物信息卡片


3,6-Diamino-9-(2-(methoxycarbonyl)phenyl)xanthylium chloride

化学式: C21H17ClN2O3 (380.09276420000003)
中文名称: 罗丹明123
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: COC(=O)C1=CC=CC=C1C2=C3C=CC(=N)C=C3OC4=C2C=CC(=C4)N.Cl
InChI: 1H

描述信息

D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents > D049408 - Luminescent Agents
D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents > D012235 - Rhodamines
D004396 - Coloring Agents > D005456 - Fluorescent Dyes

同义名列表

3 个代谢物同义名

3,6-Diamino-9-(2-(methoxycarbonyl)phenyl)xanthylium chloride; Rhodamine 123; Rhodamine 123



数据库引用编号

11 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Shagufta Iqbal, Caitlin Flux, Deborah A Briggs, Evelyne Deplazes, Jiansi Long, Ruth Skrzypek, Alice Rothnie, Ian D Kerr, Richard Callaghan. Vinca alkaloid binding to P-glycoprotein occurs in a processive manner. Biochimica et biophysica acta. Biomembranes. 2022 10; 1864(10):184005. doi: 10.1016/j.bbamem.2022.184005. [PMID: 35863425]
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  • Hana Sklenářová, Michaela Rosecká, Burkhard Horstkotte, Petr Pávek, Manuel Miró, Petr Solich. 3D printed permeation module to monitor interaction of cell membrane transporters with exogenic compounds in real-time. Analytica chimica acta. 2021 Apr; 1153(?):338296. doi: 10.1016/j.aca.2021.338296. [PMID: 33714442]
  • Liam M Koehn, Katarzyna M Dziegielewska, Mark D Habgood, Yifan Huang, Norman R Saunders. Transfer of rhodamine-123 into the brain and cerebrospinal fluid of fetal, neonatal and adult rats. Fluids and barriers of the CNS. 2021 Feb; 18(1):6. doi: 10.1186/s12987-021-00241-8. [PMID: 33557872]
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  • Yi-Nan Zhang, Yan-Fang Yang, Wei Xu, Xiu-Wei Yang. The Blood-Brain Barrier Permeability of Six Indole Alkaloids from Uncariae Ramulus Cum Uncis in the MDCK-pHaMDR Cell Monolayer Model. Molecules (Basel, Switzerland). 2017 Nov; 22(11):. doi: 10.3390/molecules22111944. [PMID: 29125571]
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  • Kentaro Yano, Saori Shimizu, Takumi Tomono, Takuo Ogihara. Gastrointestinal Hormone Cholecystokinin Increases P-Glycoprotein Membrane Localization and Transport Activity in Caco-2 Cells. Journal of pharmaceutical sciences. 2017 09; 106(9):2650-2656. doi: 10.1016/j.xphs.2017.04.003. [PMID: 28411043]
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  • Qianqian Qiu, Baomin Liu, Jian Cui, Zheng Li, Xin Deng, Hao Qiang, Jieming Li, Chen Liao, Bo Zhang, Wei Shi, Miaobo Pan, Wenlong Huang, Hai Qian. Design, Synthesis, and Pharmacological Characterization of N-(4-(2 (6,7-Dimethoxy-3,4-dihydroisoquinolin-2(1H)yl)ethyl)phenyl)quinazolin-4-amine Derivatives: Novel Inhibitors Reversing P-Glycoprotein-Mediated Multidrug Resistance. Journal of medicinal chemistry. 2017 04; 60(8):3289-3302. doi: 10.1021/acs.jmedchem.6b01787. [PMID: 28355069]
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  • Naofumi Ogushi, Kazuaki Sasaki, Minoru Shimoda. CAN a P-gp modulator assist in the control of methotrexate concentrations in the rat brain? -inhibitory effects of rhodamine 123, a specific substrate for P-gp, on methotrexate excretion from the rat brain and its optimal route of administration. The Journal of veterinary medical science. 2017 Feb; 79(2):320-327. doi: 10.1292/jvms.16-0315. [PMID: 27916761]
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  • Kazunari Iwao, Rushiana Tokie Kawai, Masako Oda, Hiroshi Saitoh. Investigation on the Interactions between Various Drugs and Aojiru (Green Juice) Using a Simple Centrifugation Method. Biological & pharmaceutical bulletin. 2017; 40(9):1566-1571. doi: 10.1248/bpb.b17-00149. [PMID: 28867740]
  • Océane Dubray, Vincent Jannin, Fréderic Demarne, Yann Pellequer, Alf Lamprecht, Arnaud Béduneau. In-vitro investigation regarding the effects of Gelucire® 44/14 and Labrasol® ALF on the secretory intestinal transport of P-gp substrates. International journal of pharmaceutics. 2016 Dec; 515(1-2):293-299. doi: 10.1016/j.ijpharm.2016.10.012. [PMID: 27720954]
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  • Tingting Guo, Jinhu Huang, Hongyu Zhang, Lingling Dong, Dawei Guo, Li Guo, Fang He, Zohaib Ahmed Bhutto, Liping Wang. Abcb1 in Pigs: Molecular cloning, tissues distribution, functional analysis, and its effect on pharmacokinetics of enrofloxacin. Scientific reports. 2016 08; 6(?):32244. doi: 10.1038/srep32244. [PMID: 27572343]
  • Erin Gallagher, Il Minn, Janice E Chambers, Peter C Searson. In vitro characterization of pralidoxime transport and acetylcholinesterase reactivation across MDCK cells and stem cell-derived human brain microvascular endothelial cells (BC1-hBMECs). Fluids and barriers of the CNS. 2016 Jul; 13(1):10. doi: 10.1186/s12987-016-0035-0. [PMID: 27396356]
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