Chemical Formula: C18H15F3N2O4

Chemical Formula C18H15F3N2O4

Found 1 metabolite its formula value is C18H15F3N2O4

IMB-808

IMB-808

C18H15F3N2O4 (380.0983866)


IMB-808 is a potent LXRα/β dual agonist with EC50 values of 0.53 μM and 0.15 μM (0.15 μM, using GAL4-pGL4-luc reporter plasmid) for LXRβ and LXRα, respectively. IMB-808 promotes expression of genes related to reverse cholesterol transport (ABCA1 and ABCG1). IMB-808 can be used as a promising agent for the prospective treatment of atherosclerosis research[1].