Exact Mass: 379.16255179999996
Exact Mass Matches: 379.16255179999996
Found 391 metabolites which its exact mass value is equals to given mass value 379.16255179999996,
within given mass tolerance error 0.05 dalton. Try search metabolite list with more accurate mass tolerance error
0.01 dalton.
Angoline
C22H21NO5 (379.14196560000005)
Angoline is a benzophenanthridine alkaloid. Angoline is a natural product found in Bocconia arborea, Zanthoxylum zanthoxyloides, and other organisms with data available. Angoline is a potent and selective IL6/STAT3 signaling pathway inhibitor with an IC50 of 11.56 μM. Angoline inhibits STAT3 phosphorylation and its target gene expression, and inhibits cancer cell proliferation[1].
kasugamycin
C14H25N3O9 (379.15907200000004)
An amino cyclitol glycoside that is isolated from Streptomyces kasugaensis and exhibits antibiotic and fungicidal properties.
Fumitremorgin C
Fumitremorgin C is produced by Aspergillus fumigatus and Neosartorya fischeri. Production by Aspergillus fumigatus and Neosartorya fischeri Fumitremorgin C. CAS Common Chemistry. CAS, a division of the American Chemical Society, n.d. https://commonchemistry.cas.org/detail?cas_rn=118974-02-0 (retrieved 2024-08-26) (CAS RN: 118974-02-0). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).
N-methyl-2,3,7,8-tetramethoxybenzophenanthridine-6(5H)-one
C22H21NO5 (379.14196560000005)
droperidol
D002492 - Central Nervous System Depressants > D014149 - Tranquilizing Agents > D014150 - Antipsychotic Agents D002491 - Central Nervous System Agents > D011619 - Psychotropic Drugs > D014149 - Tranquilizing Agents N - Nervous system > N05 - Psycholeptics > N05A - Antipsychotics > N05AD - Butyrophenone derivatives D018377 - Neurotransmitter Agents > D015259 - Dopamine Agents > D018492 - Dopamine Antagonists D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents C78272 - Agent Affecting Nervous System > C323 - Butyrophenone D005765 - Gastrointestinal Agents > D000932 - Antiemetics CONFIDENCE standard compound; INTERNAL_ID 1207 INTERNAL_ID 1207; CONFIDENCE standard compound CONFIDENCE standard compound; EAWAG_UCHEM_ID 3679 Droperidol is a butyrophenone-type Dopamine-2 receptor antagonist.
Droperidol
A butyrophenone with general properties similar to those of haloperidol. It is used in conjunction with an opioid analgesic such as fentanyl to maintain the patient in a calm state of neuroleptanalgesia with indifference to surroundings but still able to cooperate with the surgeon. It is also used as a premedicant, as an antiemetic, and for the control of agitation in acute psychoses. (From Martindale, The Extra Pharmacopoeia, 29th ed, p593) D002492 - Central Nervous System Depressants > D014149 - Tranquilizing Agents > D014150 - Antipsychotic Agents D002491 - Central Nervous System Agents > D011619 - Psychotropic Drugs > D014149 - Tranquilizing Agents N - Nervous system > N05 - Psycholeptics > N05A - Antipsychotics > N05AD - Butyrophenone derivatives D018377 - Neurotransmitter Agents > D015259 - Dopamine Agents > D018492 - Dopamine Antagonists D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents C78272 - Agent Affecting Nervous System > C323 - Butyrophenone D005765 - Gastrointestinal Agents > D000932 - Antiemetics Droperidol is a butyrophenone-type Dopamine-2 receptor antagonist.
2-(Arabinosylamino)-3-(glucosylamino)propanenitrile
C14H25N3O9 (379.15907200000004)
2-(Arabinosylamino)-3-(glucosylamino)propanenitrile is found in pulses. 2-(Arabinosylamino)-3-(glucosylamino)propanenitrile is a constituent of the seeds of Lathyrus sativus (chickling pea). Constituent of the seeds of Lathyrus sativus (chickling pea). 2-(Arabinosylamino)-3-(glucosylamino)propanenitrile is found in pulses.
Thaumatin b, recombinant
C19H29N3O3S (379.1929524000001)
Thaumatin b, recombinant is used as a food additive [EAFUS] ("EAFUS: Everything Added to Food in the United States. [http://www.eafus.com/]")
Desmethyl Erlotinib
C21H21N3O4 (379.15319860000005)
2H-1-Benzopyran-2-one, 7-[[2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl]oxy]-4-methyl-
Dacinostat
Licofelone
C23H22ClNO2 (379.13389820000003)
D018501 - Antirheumatic Agents > D000894 - Anti-Inflammatory Agents, Non-Steroidal > D016861 - Cyclooxygenase Inhibitors C78272 - Agent Affecting Nervous System > C241 - Analgesic Agent > C2198 - Nonnarcotic Analgesic D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents D004791 - Enzyme Inhibitors > D016859 - Lipoxygenase Inhibitors D002491 - Central Nervous System Agents > D000700 - Analgesics C471 - Enzyme Inhibitor > C1323 - Cyclooxygenase Inhibitor D000893 - Anti-Inflammatory Agents Licofelone (ML-3000) is a dual COX/5-lipoxygenase (5-LOX) inhibitor (IC50=0.21/0.18 μM, respectively) for the treatment of osteoarthritis. Licofelone exerts anti-inflammatory and anti-proliferative effects. Licofelone induces apoptosis, and decreases the production of proinflammatory leukotrienes and prostaglandins[1][2][3].
4H-1-Benzopyran-8-acetic acid, 4-oxo-2-phenyl-, 2-(diethylamino)ethyl ester
Merafloxacin
C19H23F2N3O3 (379.17073919999996)
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D024841 - Fluoroquinolones C254 - Anti-Infective Agent > C258 - Antibiotic > C795 - Quinolone Antibiotic
Cyclohexanecarboxamide, N-(2-((ethylsulfonyl)amino)-5-(trifluoromethyl)-3-pyridinyl)-
C15H20F3N3O3S (379.11774060000005)
8H-Purin-8-one, 7-(2-butynyl)-7,9-dihydro-9-(6-methoxy-3-pyridinyl)-6-(1-piperazinyl)-
2-(4-(3-Ethynylanilino)-6-(2-methoxyethoxy)quinazolin-7-yl)oxyethanol
C21H21N3O4 (379.15319860000005)
2-(4-(2-Methylpyridin-4-yl)phenyl)-N-(4-(pyridin-3-yl)phenyl)acetamide
Bocconoline
C22H21NO5 (379.14196560000005)
Bocconoline is a natural product found in Zanthoxylum asiaticum, Zanthoxylum simulans, and other organisms with data available.
12-Hydroxy-11-methoxy-N-acetylnor-C-fluorocurarimine
L-gamma-Glutamyl-S-4-(2-hydroxybutyl)-L-cysteinyl-glycine
This record was created by the financial support of MEXT/JSPS KAKENHI Grant Number 16HP2005 to the Mass Spectrometry Society of Japan.
L-gamma-Glutamyl-S-3-(1-hydroxybutyl)-L-cysteinyl-glycine
This record was created by the financial support of MEXT/JSPS KAKENHI Grant Number 16HP2005 to the Mass Spectrometry Society of Japan.
(3Z)-8a-methoxy-3-{[2-(2-methylbut-3-en-2-yl)-1H-indol-3-yl]methylidene}hexahydropyrrolo[1,2-a]pyrazine-1,4-dione|brevianamide R
12-hydroxy-4-methyl-8,11,15-trioxo-19H-(13betaH)-4,8-seco-crotalanane-14beta-carboxylic acid lactone|14-carboxy-8,12-dihydroxy-4alpha-methyl-11,15-dioxo-(13betaH,14betaH)-14,19-dihydro-crotalananium betaine 12-lactone|Retusamin|retusamine
11-O-acetyl bulgarsenine hydrochloride
C20H29NO6 (379.19947740000003)
14-hydroxy-2,3,6-trimethoxy-9,11,12,13,13a,14-hexahydro-dibenzo(f,h)-pyrrolo(1,2-b)-isochinolin
3-ethoxy-5-ethyl-4,5-dihydro-1-methoxy-4-oxodibenz(cd,f)indol-2-carboxylic acid ethyl ester
bruceolline M
An indole alkaloid that is 1H-indole substituted by a 3-hydroxy-3-methyl-2-oxobutyl group at position 3 and a beta-D-glucopyranosyl group attached to the indolic nitrogen. It has been isolated from the ethanol extract of the stems of Brucea mollis.
1,2,4-Trimethoxy-12,13-dihydro-12-methyl[1,3]benzodioxolo[5,6-c]phenanthridine
C22H21NO5 (379.14196560000005)
1,3,8-trihydroxy-2,7-bis-(3-methyl-but-2-enyl)-10H-acridin-9-one|Atalaphyllidin|Atalaphyllidine+|Atalaphyllin
4-desmethylisotylocrebrine|4-Hydroxy-3,6,7-trimethoxyphenanthroindolizidine
4-(9H-beta-carbolin-1-ylmethyl)-5-(1-hydroxy-ethyl)-6-oxo-1,4,5,6-tetrahydro-pyridine-3-carboxylic acid methyl ester|Hydroxylyalidin|Hydroxylyalidine
C21H21N3O4 (379.15319860000005)
Val-Tyr-Val
C19H29N3O5 (379.21071040000004)
A tripeptide formed from L-valine, L-tyrosine and L-valine residues joined in sequence.
Licofelone
C23H22ClNO2 (379.13389820000003)
D018501 - Antirheumatic Agents > D000894 - Anti-Inflammatory Agents, Non-Steroidal > D016861 - Cyclooxygenase Inhibitors C78272 - Agent Affecting Nervous System > C241 - Analgesic Agent > C2198 - Nonnarcotic Analgesic D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents D004791 - Enzyme Inhibitors > D016859 - Lipoxygenase Inhibitors D002491 - Central Nervous System Agents > D000700 - Analgesics C471 - Enzyme Inhibitor > C1323 - Cyclooxygenase Inhibitor D000893 - Anti-Inflammatory Agents Licofelone (ML-3000) is a dual COX/5-lipoxygenase (5-LOX) inhibitor (IC50=0.21/0.18 μM, respectively) for the treatment of osteoarthritis. Licofelone exerts anti-inflammatory and anti-proliferative effects. Licofelone induces apoptosis, and decreases the production of proinflammatory leukotrienes and prostaglandins[1][2][3].
(E)-1-(L-cysteinylglycin-S-yl)-N-hydroxy-omega-(methylsulfanyl)nonan-1-imine
1,3,5-trihydroxy-2,4-bis(3-methylbut-2-enyl)-10H-acridin-9-one
C22H25N3O3_9-Methoxy-12-(2-methyl-1-propen-1-yl)-1,2,3,5a,6,11,12,14a-octahydro-5H,14H-pyrrolo[1,2:4,5]pyrazino[1,2:1,6]pyrido[3,4-b]indole-5,14-dione
C24H17N3O2_(7Z)-7-Benzylidene-6-methyl-6,7-dihydroquinazolino[3,2-a][1,4]benzodiazepine-5,13-dione
Hymecromone, O-(2-Acetamido-2-deoxy-beta-D-glucopyranoside)
Coumarins
Cys Gly Asn Ser
C12H21N5O7S (379.11616360000005)
Cys Gly Ser Asn
C12H21N5O7S (379.11616360000005)
Cys Asn Gly Ser
C12H21N5O7S (379.11616360000005)
Cys Asn Ser Gly
C12H21N5O7S (379.11616360000005)
Cys Ser Gly Asn
C12H21N5O7S (379.11616360000005)
Cys Ser Asn Gly
C12H21N5O7S (379.11616360000005)
Gly Cys Asn Ser
C12H21N5O7S (379.11616360000005)
Gly Cys Ser Asn
C12H21N5O7S (379.11616360000005)
Gly Asn Cys Ser
C12H21N5O7S (379.11616360000005)
Gly Asn Ser Cys
C12H21N5O7S (379.11616360000005)
Gly Ser Cys Asn
C12H21N5O7S (379.11616360000005)
Gly Ser Asn Cys
C12H21N5O7S (379.11616360000005)
Asn Cys Gly Ser
C12H21N5O7S (379.11616360000005)
Asn Cys Ser Gly
C12H21N5O7S (379.11616360000005)
Asn Gly Cys Ser
C12H21N5O7S (379.11616360000005)
Asn Gly Ser Cys
C12H21N5O7S (379.11616360000005)
Asn Ser Cys Gly
C12H21N5O7S (379.11616360000005)
Asn Ser Gly Cys
C12H21N5O7S (379.11616360000005)
Ser Cys Gly Asn
C12H21N5O7S (379.11616360000005)
Ser Cys Asn Gly
C12H21N5O7S (379.11616360000005)
Ser Gly Cys Asn
C12H21N5O7S (379.11616360000005)
Ser Gly Asn Cys
C12H21N5O7S (379.11616360000005)
Ser Asn Cys Gly
C12H21N5O7S (379.11616360000005)
Ser Asn Gly Cys
C12H21N5O7S (379.11616360000005)
Fumitremorgin C
An organic heteropentacyclic compound that is a mycotoxic indole alkaloid produced by several fungi. A potent and specific inhibitor of the breast cancer resistance protein multidrug transporter.
Thaumatin b, recombinant
C19H29N3O3S (379.1929524000001)
2-(Arabinosylamino)-3-(glucosylamino)propanenitrile
C14H25N3O9 (379.15907200000004)
Angiotensin I-Converting Enzyme (ACE) Inactivator
C21H21N3O4 (379.15319860000005)
3-Fluoro-4-cyanophenyl trans-4- (4-n-butylcyclohexyl)benzoate
N-[[(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)-propan-2-ylamino]methyl]pyridine-3-carboxamide
N-[3-(dimethylamino)propyl]-2-methylprop-2-enamide,1-ethenylpyrrolidin-2-one,sulfuric acid
C15H29N3O6S (379.17769740000006)
7-FLUORO-3,4-DIHYDRO-4-[(5-ISOQUINOLINYLOXY)ACETYL]-3,3-DIMETHYL-2(1H)-QUINOXALINONE
C21H18FN3O3 (379.13321299999996)
7-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]-5H-[1,3]dioxolo[4,5-f]indole
TERT-BUTYL 5-((4-METHYLPIPERAZIN-1-YL)SULFONYL)-1H-INDOLE-1-CARBOXYLATE
C18H25N3O4S (379.15656900000005)
4-(4-fluorobenzoyl)piperidine p-toluenesulfonate
C19H22FNO4S (379.12535040000006)
Dibucaine hydrochloride
C78272 - Agent Affecting Nervous System > C245 - Anesthetic Agent
5-AMINOPENTANOIC ACID-BENZYL ESTER P-TOSYLATE
C19H25NO5S (379.14533600000004)
Urea, N-(4-chlorophenyl)-N-[2-[(3-cyano-8-methyl-2-quinolinyl)amino]ethyl]- (9CI)
Urea, N-(2-chlorophenyl)-N-[2-[(3-cyano-8-methyl-2-quinolinyl)amino]ethyl]- (9CI)
Urea, N-(2-chlorophenyl)-N-[2-[(3-cyano-6-methyl-2-quinolinyl)amino]ethyl]- (9CI)
cobalt,fluoren-9-one,1,2,3,4,5-pentamethylcyclopentane
L-Valine benzyl ester p-toluenesulfonate salt
C19H25NO5S (379.14533600000004)
3,7-diphenyl-6-(pyridin-2-ylmethoxy)-[1,2,4]triazolo[4,3-b]pyridazine
4-methylumbelliferyl-2-acetamido-2-deoxy-alpha-d-glucopyranoside
METHYL 4-(((BENZYLOXY)CARBONYL)AMINO)-2-FLUORO-[1,1-BIPHENYL]-3-CARBOXYLATE
METHYL 4-(((BENZYLOXY)CARBONYL)AMINO)-6-FLUORO-[1,1-BIPHENYL]-3-CARBOXYLATE
4-Methylumbelliferyl-N-acetyl-beta-D-galactosaminide hydrate
6-Oxo-2-phenyl-5-[[(phenylmethoxy)carbonyl]amino]-1(6H)-pyrimidineacetic acid
1-Benzyl-N-[(benzyloxy)carbonyl]-L-histidine
C21H21N3O4 (379.15319860000005)
BOC-THIONOVAL-1-(6-NITRO)BENZOTRIAZOLIDE
C16H21N5O4S (379.1314186000001)
Spiroxatrine
C78272 - Agent Affecting Nervous System > C29747 - Adrenergic Agent > C72900 - Adrenergic Antagonist D018377 - Neurotransmitter Agents > D015259 - Dopamine Agents > D018492 - Dopamine Antagonists Spiroxatrine (R 5188) is a selective, dual antagonist of 5-HT1α and α2-adrenergic, with the Ki values of 3.94, 224000, 118.5 nM for 5-HT1α, 5-HT1β and 5-HT2, respectively. Spiroxatrine (R 5188) has a sedative effect[1][2][3][4].
Frovatriptan
D018377 - Neurotransmitter Agents > D018490 - Serotonin Agents > D017366 - Serotonin Receptor Agonists C78272 - Agent Affecting Nervous System > C47794 - Serotonin Agonist Frovatriptan succinate hydrate ((R)-Frovatriptan succinate hydrate) is a potent, high affinity, selective and orally active 5-HT1B (pK50 of 8.2) and 5-HT1D receptor agonist. Frovatriptan succinate hydrate exhibits >10-fold selectivity for 5-HT1B and 5-HT1D over 5-HT1A, 5-HT1F, and 5-HT7 and >1000-fold selectivity over other 5-HT, dopamine, histamine H1, and α1-adrenoceptor. Frovatriptan succinate hydrate has the potential for migraine research[1][2].
5,11-Dihydro-1-(phenylmethyl)-spiro[6H-indolo[3,2-c]quinoline-6,4-piperidine]
(2R)-2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-2-methyl-6-heptenoic acid
N-FMOC-AMINO-4-KETOCYCLOHEXYLCARBOXYLIC ACID
C22H21NO5 (379.14196560000005)
(E)-2-((TERT-BUTYLDIMETHYLSILYLOXY)METHYL)-FURO[3,2-B]PYRIDINE-6-CARBALDEHYDE OXIME
1H-Pyrrolo[2,3-b]pyridine-3-ethanamine, N,N-dimethyl-1-(2-naphthalenylsulfonyl)-
C21H21N3O2S (379.13544060000004)
1-(2,3-EPOXYPROPYL)-4-PHENYLPIPERAZINE
C18H25N3O4S (379.15656900000005)
4,11-diamino-2-(3-methoxypropyl)-1H-Naphth[2,3-f]isoindole-1,3,5,10(2H)-tetrone
(3-[(ACRIDINE-9-CARBONYL)-AMINO]-PROPYL)-CARBAMIC ACID TERT-BUTYL ESTER
(2R,3R,4S,5S)-2-[6-(3-bicyclo[2.2.1]heptanylamino)purin-9-yl]-5-(chloromethyl)oxolane-3,4-diol
C17H22ClN5O3 (379.1411092000001)
Tetrahydropapaverine hydrochloride
C20H26ClNO4 (379.1550266000001)
Tetrahydropapaverine hydrochloride is one of the Tetrahydroisoquinolines. Tetrahydropapaverine hydrochloride has neurotoxic effects on dopamine neurons[1][2].
6-((1-(3-FLUORO-5-(TRIFLUOROMETHYL)BENZYL)PIPERIDIN-4-YL)AMINO)PYRIDAZINE-3-CARBONITRILE
N-[2-(3,4-dimethoxyphenyl)ethyl]-1-(2,6-dimethylphenoxy)propan-2-amine,hydrochloride
4-(4-METHYL-5-(2-(TRIFLUOROMETHYL)PHENYL)-4H-1,2,4-TRIAZOL-3-YL)BICYCLO[2.2.2]OCTANE-1-CARBOXYLIC ACID
C19H20F3N3O2 (379.15075360000003)
N-(2-hydroxy-1-methyl-2-phenylethyl)-N,7,7-trimethyl-2-oxobicyclo[2.2.1]heptane-1-methanesulphonamide
C20H29NO4S (379.1817194000001)
4-[(2-Butyl-4-chloro-5-hydroxymethyl-1H-imidazol-1-yl)methyl]-1,1-biphenyl-2-carbonitrile
C22H22ClN3O (379.14513120000004)
3-[1-(9H-fluoren-9-ylmethoxycarbonyl)piperidin-4-yl]propanoic acid
(3S)-3-cyclopentyl-3-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic acid
2-[4-[2-[4-(3-methyl-1,2,4-oxadiazol-5-yl)phenyl]vinyl]phenyl]benzoxazole
(4-N-(Benzhydryloxycarbonyl)cytosine)-1-acetic acid
Desmethyl Erlotinib
C21H21N3O4 (379.15319860000005)
dicyclohexylamine (S)-2-hydroxy-4-(methylselanyl)butanoate
C17H33NO3Se (379.16255179999996)
(3-Chloro-5-trifluoroMethyl-3,4,5,6-tetrahydro-2H-[1,2]bipyridinyl-3-yl)-carbaMic acid tert-butyl ester
1-[4-(4.4.5.5-tetramethyl-[1.3.2]dioxaborolan-2-yl)-biphenyl-4-yl]-cyclopropanecarboxylic acid methyl ester
4-{4-[BIS(4-FLUOROPHENYL)METHYL]PIPERAZIN-1-YL}PHENYLAMINE
Z-L-aspartic acid di-tert·butyl ester
C20H29NO6 (379.19947740000003)
Atevirdine
C471 - Enzyme Inhibitor > C1589 - Reverse Transcriptase Inhibitor > C97453 - Non-nucleoside Reverse Transcriptase Inhibitor D000890 - Anti-Infective Agents > D000998 - Antiviral Agents > D018894 - Reverse Transcriptase Inhibitors D004791 - Enzyme Inhibitors > D019384 - Nucleic Acid Synthesis Inhibitors C254 - Anti-Infective Agent > C281 - Antiviral Agent
1-(2-AMINO-PHENYL)-PIPERIDIN-3-CARBAMICACIDTERT-BUYTLESTER
C21H21N3O4 (379.15319860000005)
Dacinostat
C471 - Enzyme Inhibitor > C1946 - Histone Deacetylase Inhibitor C274 - Antineoplastic Agent > C163758 - Targeted Therapy Agent
6-N-BUTYL-2-(3,4-DIMETHOXYPHENYL)-8-METHYLQUINOLINE-4-CARBOXYLIC ACID
4-Methylumbelliferyl 2-amino-2-deoxy-a-D-glucopyranoside
5-(3-((2S)-(1,4-Benzodioxan-2-ylmethyl)amino)propoxy)-1,3-benzodioxol hydrochloride
C19H22ClNO5 (379.11864320000007)
n-[3-(n-Hydroxycarboxamido)-2-(2-methylpropyl)-propanoyl]-o-tyrosine-n-methylamide
C19H29N3O5 (379.21071040000004)
D004791 - Enzyme Inhibitors > D011480 - Protease Inhibitors > D061965 - Matrix Metalloproteinase Inhibitors
1-Piperazinepropanoic acid, 4-dibenz(b,f)(1,4)oxazepin-11-yl-alpha,alpha-dimethyl-
(6E)-2,5-diamino-6-[5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-ylidene]hexanoic acid
C15H21N7O5 (379.16040960000004)
Fuzapladib
C15H20F3N3O3S (379.11774060000005)
C274 - Antineoplastic Agent > C1742 - Angiogenesis Inhibitor > C2144 - Endothelial-Specific Integrin/Survival Signaling Inhibitor D004791 - Enzyme Inhibitors > D064801 - Phospholipase A2 Inhibitors C308 - Immunotherapeutic Agent > C574 - Immunosuppressant Fuzapladib (IS-741), an orally active leukocyte-function-associated antigen type 1 (LFA-1) activation inhibitor, is a leukocyte adhesion molecule. Fuzapladib is also a phospholipase A2 (PLA2) inhibitor. Fuzapladib exerts anti-inflammatory effects by inhibiting leukocyte migration into the inflammatory site[1][2].
8H-Purin-8-one, 7-(2-butynyl)-7,9-dihydro-9-(6-methoxy-3-pyridinyl)-6-(1-piperazinyl)-
N2,N2-dimethyl-6-[[[1-(1-naphthalenyl)-5-tetrazolyl]thio]methyl]-1,3,5-triazine-2,4-diamine
7-Hydroxy-3-(2-methoxyphenyl)-8-[(4-methyl-1-piperidinyl)methyl]-1-benzopyran-4-one
methyl 4-{3-[1-(3-nitro-2-pyridinyl)-4-piperidinyl]-1H-pyrazol-5-yl}phenyl ether
C20H21N5O3 (379.16443160000006)
6-[2-amino-5-(4-methoxyphenoxy)-1H-pyrimidin-6-ylidene]-3-(2-methylprop-2-enoxy)-1-cyclohexa-2,4-dienone
C21H21N3O4 (379.15319860000005)
2-[(4-Chlorophenyl)methyl]-6-phenyl-5-(1-piperidinyl)-3-pyridazinone
C22H22ClN3O (379.14513120000004)
2-[(3-Chlorophenyl)methyl]-6-phenyl-5-(1-piperidinyl)-3-pyridazinone
C22H22ClN3O (379.14513120000004)
5-Tert-butyl-3-(4-chlorophenyl)-7-(2-ethyl-1-imidazolyl)pyrazolo[1,5-a]pyrimidine
C21H22ClN5 (379.15636420000004)
2-[[Cyclohexyl(oxo)methyl]amino]acetic acid (2-oxo-1,2-diphenylethyl) ester
3-{2-[(propan-2-yl)amino]acetamido}-N-[3-(trifluoromethyl)phenyl]benzamide
C19H20F3N3O2 (379.15075360000003)
3-[Isopropyl(4-methylbenzoyl)amino]-5-phenylthiophene-2-carboxylic acid
C22H21NO3S (379.1242076000001)
1-ethyl-N-(phenylmethyl)-4-(tetrahydro-2H-pyran-4-ylamino)-1H-pyrazolo[3,4-b]pyridine-5-carboxamide
1-(5-Chloro-2-Methoxyphenyl)-3-{6-[2-(Dimethylamino)-1-Methylethoxy]pyrazin-2-Yl}urea
C17H22ClN5O3 (379.1411092000001)
[1-Propylsulfonyl-4-[[2-(trifluoromethyl)phenyl]methyl]piperidin-4-yl]methanol
C17H24F3NO3S (379.1428910000001)
Thaumatin b, recombinant
C19H29N3O3S (379.1929524000001)
Thaumatin b, recombinant is used as a food additive [EAFUS] ("EAFUS: Everything Added to Food in the United States. [http://www.eafus.com/]") D000074385 - Food Ingredients > D005503 - Food Additives D010592 - Pharmaceutic Aids > D005421 - Flavoring Agents
1-hydroxy-3-[(2E,4E,6E)-8-methyldeca-2,4,6-trienoyl]-5-(4-oxidophenyl)-2-oxopyridin-4-olate
C22H21NO5-2 (379.14196560000005)
3,3-Dimethyl-2-oxobutyric acid 5-(6-aminopurin-9-yl)-3,4-dihydroxytetrahydrofuran-2-ylmethyl ester
C16H21N5O6 (379.14917660000003)
L-Tyr-3-[[(E)-4-Methoxy-4-oxo-2-butenoyl]amino]-L-Ala-OH
2-[[(2R)-2-amino-3-[(E)-N-hydroxy-C-(8-methylsulfanyloctyl)carbonimidoyl]sulfanylpropanoyl]amino]acetic acid
(S)-2-((S)-2-((S)-2-Amino-3-methylbutanamido)-3-(4-hydroxyphenyl)propanamido)-3-methylbutanoic acid
C19H29N3O5 (379.21071040000004)
5-amino-2-(1-ethylpropyl)-6-[(Z)-(2-methylindol-3-ylidene)methyl]-[1,3,4]thiadiazolo[3,2-a]pyrimidin-7-one
C20H21N5OS (379.14667360000004)
1-Benzimidazolyl-[2-(4-methoxyphenyl)-4-quinolinyl]methanone
N-[1-(2-chloro-6-fluorobenzyl)-4-piperidinyl]-N-(4-fluorophenyl)urea
ethyl N-[(E)-[1-[3-(4-methylphenoxy)propyl]indol-3-yl]methylideneamino]carbamate
1-[4-(4-Phenoxyphenyl)-2-thiazolyl]-4-piperidinecarboxamide
C21H21N3O2S (379.13544060000004)
Phe-Val-Asp
A tripeptide composed of L-phenylalanine, L-valine, and L-aspartic acid joined by peptide linkages.
Tyr-FMDP
A dipeptide composed of 3-{[(2E)-4-methoxy-4-oxobut-2-enoyl]amino}alanine and L-tyrosine joined by peptide linkages.
N-[3-(3,4-dihydro-1H-isoquinolin-2-yl)propyl]-2-(3-oxo-1,4-benzoxazin-4-yl)acetamide
2-{[(2-butoxyquinolin-4-yl)carbonyl]amino}-N,N-diethylethanaminium chloride
2-[[2-(4-Methoxyphenyl)-6-methyl-1-benzopyran-4-ylidene]amino]-4-methylpentanoic acid
2-[[2-(3,4-dihydro-2H-quinolin-1-yl)-2-oxoethyl]thio]-3-ethyl-4-quinazolinone
C21H21N3O2S (379.13544060000004)
2-Methyl-1-phenyl-5-benzimidazolecarboxylic acid [2-(3-methylbutan-2-ylamino)-2-oxoethyl] ester
(5E)-3-[(2-fluorophenyl)methyl]-5-[[1-(4-fluorophenyl)pyrrol-2-yl]methylidene]imidazolidine-2,4-dione
1-(1,4-dioxan-2-yl)-N-[[3-(diphenylmethyl)-1,2,4-oxadiazol-5-yl]methyl]-N-methylmethanamine
1-(2,3-Dihydroindol-1-yl)-2-[(4-propyl-5-pyridin-4-yl-1,2,4-triazol-3-yl)thio]ethanone
C20H21N5OS (379.14667360000004)
4-[(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)methyl]-7-ethyl-1-benzopyran-2-one
1-(12-oxo-7,8,9,10-tetrahydro-6H-azepino[2,1-b]quinazolin-2-yl)-3-(3-pyridinylmethyl)thiourea
C20H21N5OS (379.14667360000004)
N-[1-(3,4-dimethylphenyl)-4,5,6,7-tetrahydroindazol-4-yl]-5-(methoxymethyl)-2-furancarboxamide
(2S,3R,4R)-1-[2-(dimethylamino)-1-oxoethyl]-4-(hydroxymethyl)-3-[4-(2-methoxyphenyl)phenyl]-2-azetidinecarbonitrile
(2S,3S,4R)-1-[2-(dimethylamino)-1-oxoethyl]-4-(hydroxymethyl)-3-[4-(2-methoxyphenyl)phenyl]-2-azetidinecarbonitrile
(2S,3R,4S)-3-[4-(1-cyclohexenyl)phenyl]-1-(5-ethyl-2-thiazolyl)-4-(hydroxymethyl)-2-azetidinecarbonitrile
(2R,3S,4S)-3-[4-(1-cyclohexenyl)phenyl]-1-(5-ethyl-2-thiazolyl)-4-(hydroxymethyl)-2-azetidinecarbonitrile
(2R,3R,4R)-1-[2-(dimethylamino)-1-oxoethyl]-4-(hydroxymethyl)-3-[4-(2-methoxyphenyl)phenyl]-2-azetidinecarbonitrile
(2R,3R,4S)-3-[4-(1-cyclohexenyl)phenyl]-1-(5-ethyl-2-thiazolyl)-4-(hydroxymethyl)-2-azetidinecarbonitrile
(2R,3R,4R)-3-[4-(1-cyclohexenyl)phenyl]-1-(5-ethyl-2-thiazolyl)-4-(hydroxymethyl)-2-azetidinecarbonitrile
(2S,3S,4S)-3-[4-(1-cyclohexenyl)phenyl]-1-(5-ethyl-2-thiazolyl)-4-(hydroxymethyl)-2-azetidinecarbonitrile
N-(cyclopropylmethyl)-2-[(2R,5R,6S)-5-[[(3-fluoroanilino)-oxomethyl]amino]-6-(hydroxymethyl)-2-oxanyl]acetamide
C19H26FN3O4 (379.19072480000005)
N-(cyclopropylmethyl)-2-[(2S,5S,6S)-5-[[(3-fluoroanilino)-oxomethyl]amino]-6-(hydroxymethyl)-2-oxanyl]acetamide
C19H26FN3O4 (379.19072480000005)
N-(cyclopropylmethyl)-2-[(2R,5S,6S)-5-[[(3-fluoroanilino)-oxomethyl]amino]-6-(hydroxymethyl)-2-oxanyl]acetamide
C19H26FN3O4 (379.19072480000005)
(2R,3S,4R)-1-[2-(dimethylamino)-1-oxoethyl]-4-(hydroxymethyl)-3-[4-(2-methoxyphenyl)phenyl]-2-azetidinecarbonitrile
(2S,3S,4S)-1-[2-(dimethylamino)-1-oxoethyl]-4-(hydroxymethyl)-3-[4-(2-methoxyphenyl)phenyl]-2-azetidinecarbonitrile
(2S,3R,4R)-3-[4-(1-cyclohexenyl)phenyl]-1-(5-ethyl-2-thiazolyl)-4-(hydroxymethyl)-2-azetidinecarbonitrile
N-(cyclopropylmethyl)-2-[(2S,5R,6S)-5-[[(3-fluoroanilino)-oxomethyl]amino]-6-(hydroxymethyl)-2-oxanyl]acetamide
C19H26FN3O4 (379.19072480000005)
N-(cyclopropylmethyl)-2-[(2R,5S,6R)-5-[[(3-fluoroanilino)-oxomethyl]amino]-6-(hydroxymethyl)-2-oxanyl]acetamide
C19H26FN3O4 (379.19072480000005)
N-(cyclopropylmethyl)-2-[(2S,5S,6R)-5-[[(3-fluoroanilino)-oxomethyl]amino]-6-(hydroxymethyl)-2-oxanyl]acetamide
C19H26FN3O4 (379.19072480000005)
N-(cyclopropylmethyl)-2-[(2R,5R,6R)-5-[[(3-fluoroanilino)-oxomethyl]amino]-6-(hydroxymethyl)-2-oxanyl]acetamide
C19H26FN3O4 (379.19072480000005)
N-(cyclopropylmethyl)-2-[(2S,5R,6R)-5-[[(3-fluoroanilino)-oxomethyl]amino]-6-(hydroxymethyl)-2-oxanyl]acetamide
C19H26FN3O4 (379.19072480000005)
(2R,3S,4S)-1-[2-(dimethylamino)-1-oxoethyl]-4-(hydroxymethyl)-3-[4-(2-methoxyphenyl)phenyl]-2-azetidinecarbonitrile
(2R,3S,4R)-3-[4-(1-cyclohexenyl)phenyl]-1-(5-ethyl-2-thiazolyl)-4-(hydroxymethyl)-2-azetidinecarbonitrile
N-(2-chloroethyl)-N-(6-chloro-2-methoxyacridin-9-yl)propane-1,3-bis(aminium)
thaumatin
C19H29N3O3S (379.1929524000001)
D000074385 - Food Ingredients > D005503 - Food Additives D010592 - Pharmaceutic Aids > D005421 - Flavoring Agents
Triphyopeltine
An isoquinoline alkaloid that is the biaryl resulting from substitution of the hydrogen at the 7-position of (1R,3R)-1,3-dimethyl-1,2,3,4-tetrahydroisoquinolin-8-ol by a 1-hydroxy-6-(hydroxymethyl)-8-methoxynaphthalen-5-yl group. It is a naphthylisoquinoline alkaloid found in Triphyophyllum peltatum.
Thr-Pro-Tyr
A tripeptide composed of L-threonine, L-proline, and L-tyrosine joined by peptide linkages.
2-methylthio-N(6)-(cis-4-hydroxy-Delta(2)-isopentenyl)adenosine residue
C16H21N5O4S (379.1314186000001)
A nucleoside residue in which an adenosine residue has been modified by substitution at C-2 by a methylthio (methylsulfanyl) group and at the 6-amino nitrogen by a cis-4-hydroxy-Delta(2)-isopentenyl group.
N(6)-dansyl-L-lysine
C18H25N3O4S (379.15656900000005)
An L-lysine derivative with a dansyl group at the N(6)-position.
ML381
C21H21N3O4 (379.15319860000005)
ML381 (VU0488130) is a highly selective, central nervous system penetrant mAChR M5 orthogonal antagonist (IC50 = 450 nM; Ki = 340 nM). ML381 is unstable in rat plasma and can be mainly used as a molecular probe for in vitro and electrophysiological studies[1][2].
ML417
ML417 is a selective and brain penetrant D3 dopamine receptor (D3R) agonist, with an EC50 of 38 nM. ML417 potently promotes D3R-mediated β-arrestin translocation, G protein mediated signaling, and pERK phosphorylation with minimal effects on other GPCR-mediated signaling. ML417 exhibits neuroprotection against toxin-induced neurodegeneration of dopaminergic neurons[1]. ML417 is a selective and brain penetrant D3 dopamine receptor (D3R) agonist, with an EC50 of 38 nM. ML417 potently promotes D3R-mediated β-arrestin translocation, G protein mediated signaling, and pERK phosphorylation with minimal effects on other GPCR-mediated signaling. ML417 exhibits neuroprotection against toxin-induced neurodegeneration of dopaminergic neurons[1].