Exact Mass: 377.10203340000004
Exact Mass Matches: 377.10203340000004
Found 258 metabolites which its exact mass value is equals to given mass value 377.10203340000004
,
within given mass tolerance error 0.05 dalton. Try search metabolite list with more accurate mass tolerance error
0.01 dalton.
6-(2-Hydroxyethyl)-5,6-dihydrosanguinarine
C22H19NO5 (377.12631640000006)
JNJ-38877605
C19H13F2N7 (377.12004420000005)
C274 - Antineoplastic Agent > C2189 - Signal Transduction Inhibitor > C129824 - Antineoplastic Protein Inhibitor C274 - Antineoplastic Agent > C163758 - Targeted Therapy Agent > C164000 - c-Met-targeting Agent C471 - Enzyme Inhibitor > C1404 - Protein Kinase Inhibitor > C1967 - Tyrosine Kinase Inhibitor C471 - Enzyme Inhibitor > C129825 - Antineoplastic Enzyme Inhibitor
Kinetin-7-N-glucoside
Kinetin-7-N-glucoside belongs to the class of organic compounds known as glycosylamines. Glycosylamines are compounds consisting of an amine with a beta-N-glycosidic bond to a carbohydrate, thus forming a cyclic hemiaminal ether bond (alpha-amino ether). Kinetin-7-N-glucoside is a strong basic compound (based on its pKa). Kinetin-7-N-glucoside is the product of the reaction between kinetin and UDP-D-glucose, with UDP as a co-product. The reaction is catalyzed by a UDP glycosyltransferase. Kinetin-7-N-glucoside is the product of the reaction between kinetin and UDP-D-glucose, with UDP as a co-product. The reaction is catalyzed by a UDP glycosyltransferase. [HMDB]
Kinetin-9-N-glucoside
Kinetin-9-N-glucoside belongs to the class of organic compounds known as glycosylamines. Glycosylamines are compounds consisting of an amine with a beta-N-glycosidic bond to a carbohydrate, thus forming a cyclic hemiaminal ether bond (alpha-amino ether). Kinetin-9-N-glucoside is a strong basic compound (based on its pKa). Kinetin-9-N-glucoside is the product of the reaction between kinetin and UDP-D-glucose, with UDP as a co-product. The reaction is catalyzed by a UDP glycosyltransferase.
S-(2-Hydroxy-3-buten-1-yl)glutathione
4-(4-Fluorophenyl)-2-(4-methylsulfinylphenyl)-5-(4-pyridyl)-1H-imidazole
7H-Pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid, 9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-, N-oxide
C18H20FN3O5 (377.13869220000004)
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D024841 - Fluoroquinolones
Methyl 4-(2-(2-hydroxy-2-(3-chlorophenyl)ethylamino)propyl)phenoxyacetate
C20H24ClNO4 (377.13937740000006)
D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents > D000322 - Adrenergic Agonists
(2S)-2-(Butanoylamino)-5-[[(1R)-2-(carboxymethylamino)-2-oxo-1-(sulfanylmethyl)ethyl]amino]-5-oxo-pentanoic acid
S-Pyruvylglutathione
Lasmiditan
N - Nervous system > N02 - Analgesics > N02C - Antimigraine preparations > N02CC - Selective serotonin (5ht1) agonists D018377 - Neurotransmitter Agents > D018490 - Serotonin Agents > D017366 - Serotonin Receptor Agonists C78272 - Agent Affecting Nervous System > C47794 - Serotonin Agonist
Ethoxysanguinarine
C22H19NO5 (377.12631640000006)
Ethoxysanguinarine is a benzophenanthridine alkaloid natural product that is mainly found in Macleaya cordata. Ethoxysanguinarine is an inhibitor of protein phosphatase 2A (CIP2A). Ethoxysanguinarine induces cell apoptosis and inhibits colorectal cancer cells growth[1]. Ethoxysanguinarine is a benzophenanthridine alkaloid natural product that is mainly found in Macleaya cordata. Ethoxysanguinarine is an inhibitor of protein phosphatase 2A (CIP2A). Ethoxysanguinarine induces cell apoptosis and inhibits colorectal cancer cells growth[1].
Phellodendrine HCl
C20H24NO4+.Cl- (377.13937740000006)
Phellodendrine chloride is a plant alkaloid found in Phellodendron amurense. Phellodendrine chloride suppresses the proliferation of KRAS mutated pancreatic cancer cells through inhibition of nutrients uptake via macropinocytosis [1]. Phellodendrine chloride promotes autophagy by regulating the AMPK/mTOR pathway and reduce the intestinal damage of ulcerative colitis[2]. Phellodendrine chloride is a plant alkaloid found in Phellodendron amurense. Phellodendrine chloride suppresses the proliferation of KRAS mutated pancreatic cancer cells through inhibition of nutrients uptake via macropinocytosis [1]. Phellodendrine chloride promotes autophagy by regulating the AMPK/mTOR pathway and reduce the intestinal damage of ulcerative colitis[2].
Phellodendrine
C20H24NO4+.Cl- (377.13937740000006)
Phellodendrine chloride is a plant alkaloid found in Phellodendron amurense. Phellodendrine chloride suppresses the proliferation of KRAS mutated pancreatic cancer cells through inhibition of nutrients uptake via macropinocytosis [1]. Phellodendrine chloride promotes autophagy by regulating the AMPK/mTOR pathway and reduce the intestinal damage of ulcerative colitis[2]. Phellodendrine chloride is a plant alkaloid found in Phellodendron amurense. Phellodendrine chloride suppresses the proliferation of KRAS mutated pancreatic cancer cells through inhibition of nutrients uptake via macropinocytosis [1]. Phellodendrine chloride promotes autophagy by regulating the AMPK/mTOR pathway and reduce the intestinal damage of ulcerative colitis[2].
Piscerythoxazole
C22H19NO5 (377.12631640000006)
L-gamma-glutamyl-S-3-(1-oxobutyl)-L-cysteinyl-glycine
This record was created by the financial support of MEXT/JSPS KAKENHI Grant Number 16HP2005 to the Mass Spectrometry Society of Japan.
O1-(2-acetylamino-[1]naphthyl)-beta-D-glucopyranuronic acid|O1-(2-Acetylamino-[1]naphthyl)-beta-D-glucopyranuronsaeure
4-methoxyfuro[2,3-b]quinolin-7-yl beta-D-mannopyranoside|dictamnine-7-beta-D-mannopyranoside
S-methyl-5-thio-[3]adenylic acid|Thiomethyladenosin
C11H16N5O6PS (377.05588860000006)
(-)-circumdatin J|(S)-(-)-circumdatin J|(S)-2,12-dimethoxy-5b,6,7,8-tetrahydrobenzo[6,7]pyrrolo[2,1:3,4][1,4]diazepino[2,1-b]quinazoline-10,16-dione|circumdatin J
C21H19N3O4 (377.13754940000007)
(2-hydroxy-1-methoxy-12-methyl-12,13-dihydro-[1,3]dioxolo[4,5:4,5]benzo[1,2-c]phenanthridin-13-yl)-acetaldehyde|11-(Formyl-methylenyl)-O-desmethyl-dihydrochelerythrin
C22H19NO5 (377.12631640000006)
bruceolline K
An indole alkaloid that is 1,2,3,4-tetrahydrocyclopenta[b]indole substituted by geminal-methyl groups at position 3, an oxo group at position 1 and a beta-D-glucopyranosyloxy group at position 2.It has been isolated from the ethanol extract of the stems of Brucea mollis.
O1-(6-acetylamino-[2]naphthyl)-beta-D-glucopyranuronic acid|O1-(6-Acetylamino-[2]naphthyl)-beta-D-glucopyranuronsaeure
16-Methoxycarbonyl-18,19-dihydroxynaufoline
C21H19N3O4 (377.13754940000007)
14-Ethoxy-13-methyl-13,14-dihydro-[1,3]dioxolo[4,5:4,5]benzo[1,2-c][1,3]dioxolo[4,5-i]phenanthridine
C22H19NO5 (377.12631640000006)
SB 203580
D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents D002491 - Central Nervous System Agents > D000700 - Analgesics D000893 - Anti-Inflammatory Agents D018501 - Antirheumatic Agents C308 - Immunotherapeutic Agent D004791 - Enzyme Inhibitors
Cissamine chloride
C20H24ClNO4 (377.13937740000006)
Cyclanoline (chloride) shows cholinesterase inhibitory activity[1].
Escholine chloride
C20H24ClNO4 (377.13937740000006)
Magnoflorine chloride (Magnoflorine chloride), an aporphine alkaloid found in Magnolia or Aristolochia, reduces the formation of C. albicans biofilm[1]. Magnoflorine chloride has anti-fungal, anti-antidiabetic and anti-oxidative activity[2]. Magnoflorine chloride (Magnoflorine chloride), an aporphine alkaloid found in Magnolia or Aristolochia, reduces the formation of C. albicans biofilm[1]. Magnoflorine chloride has anti-fungal, anti-antidiabetic and anti-oxidative activity[2].
Phellodendrine HCl
C20H24ClNO4 (377.13937740000006)
Phellodendrine chloride is a plant alkaloid found in Phellodendron amurense. Phellodendrine chloride suppresses the proliferation of KRAS mutated pancreatic cancer cells through inhibition of nutrients uptake via macropinocytosis [1]. Phellodendrine chloride promotes autophagy by regulating the AMPK/mTOR pathway and reduce the intestinal damage of ulcerative colitis[2]. Phellodendrine chloride is a plant alkaloid found in Phellodendron amurense. Phellodendrine chloride suppresses the proliferation of KRAS mutated pancreatic cancer cells through inhibition of nutrients uptake via macropinocytosis [1]. Phellodendrine chloride promotes autophagy by regulating the AMPK/mTOR pathway and reduce the intestinal damage of ulcerative colitis[2].
Phentolamine mesilate
C18H23N3O4S (377.14091980000006)
Phentolamine mesylate (Phentolamine methanesulfonate) is a reversible, non-selective, and orally active blocker of α1 and α2 adrenergic receptor that expands blood vessels to reduce peripheral vascular resistance. Phentolamine mesylate can be used for the research of pheochromocytoma-related hypertension, heart failure and erectile dysfunction[1][2][3].
FR167356
C19H17Cl2NO3 (377.05854320000003)
CONFIDENCE standard compound; INTERNAL_ID 245; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8799; ORIGINAL_PRECURSOR_SCAN_NO 8796 CONFIDENCE standard compound; INTERNAL_ID 245; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8818; ORIGINAL_PRECURSOR_SCAN_NO 8815 CONFIDENCE standard compound; INTERNAL_ID 245; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8849; ORIGINAL_PRECURSOR_SCAN_NO 8845 CONFIDENCE standard compound; INTERNAL_ID 245; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8855; ORIGINAL_PRECURSOR_SCAN_NO 8850 CONFIDENCE standard compound; INTERNAL_ID 245; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8828; ORIGINAL_PRECURSOR_SCAN_NO 8825 CONFIDENCE standard compound; INTERNAL_ID 245; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8869; ORIGINAL_PRECURSOR_SCAN_NO 8867
Ala Ala Cys Asn
C13H23N5O6S (377.13689780000004)
Ala Ala Asn Cys
C13H23N5O6S (377.13689780000004)
Ala Cys Ala Asn
C13H23N5O6S (377.13689780000004)
Ala Cys Gly Gln
C13H23N5O6S (377.13689780000004)
Ala Cys Asn Ala
C13H23N5O6S (377.13689780000004)
Ala Cys Gln Gly
C13H23N5O6S (377.13689780000004)
Ala Gly Cys Gln
C13H23N5O6S (377.13689780000004)
Ala Gly Gln Cys
C13H23N5O6S (377.13689780000004)
Ala Asn Ala Cys
C13H23N5O6S (377.13689780000004)
Ala Asn Cys Ala
C13H23N5O6S (377.13689780000004)
Ala Gln Cys Gly
C13H23N5O6S (377.13689780000004)
Ala Gln Gly Cys
C13H23N5O6S (377.13689780000004)
Cys Ala Ala Asn
C13H23N5O6S (377.13689780000004)
Cys Ala Gly Gln
C13H23N5O6S (377.13689780000004)
Cys Ala Asn Ala
C13H23N5O6S (377.13689780000004)
Cys Ala Gln Gly
C13H23N5O6S (377.13689780000004)
Cys Gly Ala Gln
C13H23N5O6S (377.13689780000004)
Cys Gly Gln Ala
C13H23N5O6S (377.13689780000004)
Cys Asn Ala Ala
C13H23N5O6S (377.13689780000004)
Cys Gln Ala Gly
C13H23N5O6S (377.13689780000004)
Cys Gln Gly Ala
C13H23N5O6S (377.13689780000004)
Gly Ala Cys Gln
C13H23N5O6S (377.13689780000004)
Gly Ala Gln Cys
C13H23N5O6S (377.13689780000004)
Gly Cys Ala Gln
C13H23N5O6S (377.13689780000004)
Gly Cys Gln Ala
C13H23N5O6S (377.13689780000004)
Gly Gly Met Asn
C13H23N5O6S (377.13689780000004)
Gly Gly Asn Met
C13H23N5O6S (377.13689780000004)
Gly Met Gly Asn
C13H23N5O6S (377.13689780000004)
Gly Met Asn Gly
C13H23N5O6S (377.13689780000004)
Gly Asn Gly Met
C13H23N5O6S (377.13689780000004)
Gly Asn Met Gly
C13H23N5O6S (377.13689780000004)
Gly Gln Ala Cys
C13H23N5O6S (377.13689780000004)
Gly Gln Cys Ala
C13H23N5O6S (377.13689780000004)
Met Gly Gly Asn
C13H23N5O6S (377.13689780000004)
Met Gly Asn Gly
C13H23N5O6S (377.13689780000004)
Met Asn Gly Gly
C13H23N5O6S (377.13689780000004)
Asn Ala Ala Cys
C13H23N5O6S (377.13689780000004)
Asn Ala Cys Ala
C13H23N5O6S (377.13689780000004)
Asn Cys Ala Ala
C13H23N5O6S (377.13689780000004)
Asn Gly Gly Met
C13H23N5O6S (377.13689780000004)
Asn Gly Met Gly
C13H23N5O6S (377.13689780000004)
Asn Met Gly Gly
C13H23N5O6S (377.13689780000004)
Gln Ala Cys Gly
C13H23N5O6S (377.13689780000004)
Gln Ala Gly Cys
C13H23N5O6S (377.13689780000004)
Gln Cys Ala Gly
C13H23N5O6S (377.13689780000004)
Gln Cys Gly Ala
C13H23N5O6S (377.13689780000004)
Gln Gly Ala Cys
C13H23N5O6S (377.13689780000004)
Gln Gly Cys Ala
C13H23N5O6S (377.13689780000004)
4-(2-Chlorophenyl)-5-methoxycabonyl-3-ethoxycarbonyl-6-methylpicolinic acid
C18H16ClNO6 (377.06661060000005)
3-[[2-(4-phenylmethoxyphenoxy)acetyl]amino]benzoic acid
C22H19NO5 (377.12631640000006)
disperse blue 124
C16H19N5O4S (377.11576940000003)
4-Phenylpiperidine-4-carboxylic acid, compound with toluene-p-sulphonic acid
C19H23NO5S (377.12968680000006)
diethyl (6-chloro-2,3,4,9-tetrahydro-1H-carbazol-2-yl)methylmalonate
C20H24ClNO4 (377.13937740000006)
1-(4-nitrophenyl)-1,2,2-triphenylethylene
C26H19NO2 (377.14157140000003)
2-Carboxy-5-fluoro-1-[(1-naphthalenyl)methyl]-1H-indole-3-acetic acid
tert-Butyl 2-bromo-3-cyclohexyl-1H-indole-6-carboxylate
2H-Pyrrol-2-one, 4-acetyl-1-(4-bromophenyl)-5-cyclohexyl-1,5-dihydro-3-hydroxy-
C18H20BrNO3 (377.0626470000001)
Ronifibrate
C19H20ClNO5 (377.1029940000001)
C78276 - Agent Affecting Digestive System or Metabolism > C29703 - Antilipidemic Agent > C98150 - Fibrate Antilipidemic Agent C - Cardiovascular system > C10 - Lipid modifying agents > C10A - Lipid modifying agents, plain > C10AB - Fibrates
5-(4-TERT-BUTYLPHENYL)-4-[3-(TRIFLUOROMETHYL)PHENYL]-1,2,4-TRIAZOLE-3-THIOL
C19H18F3N3S (377.11734640000003)
(4-(N-Butyl-N-(4-methoxybenzyl)sulfamoyl)phenyl)boronic acid
C18H24BNO5S (377.14681640000003)
1-PIPERIDINECARBOXYLIC ACID 4-(4-IODO-1H-PYRAZOL-1YL)-,1-1-DIMETHYLETHYLESTER
1-(3,4-Dimethoxybenzyl)-6,7-dimethoxy-3,4-dihydroisoquinoline hydrochloride
C20H24ClNO4 (377.13937740000006)
CH5132799
C15H19N7O3S (377.12700240000004)
C274 - Antineoplastic Agent > C163758 - Targeted Therapy Agent > C2152 - Phosphatidylinositide 3-Kinase Inhibitor C274 - Antineoplastic Agent > C2189 - Signal Transduction Inhibitor > C129824 - Antineoplastic Protein Inhibitor C471 - Enzyme Inhibitor > C129825 - Antineoplastic Enzyme Inhibitor C274 - Antineoplastic Agent > C1742 - Angiogenesis Inhibitor C471 - Enzyme Inhibitor > C1404 - Protein Kinase Inhibitor
1,2-di-o-acetyl-3-azido-3-deoxy-5-o-toluoyl-d-ribofuranose
Methyl 2-BroMo-3-(4-(2-(3-Methylpyridin-2-yl)ethoxy)phenyl)propanoate
C18H20BrNO3 (377.0626470000001)
Selurampanel
C16H19N5O4S (377.11576940000003)
C78272 - Agent Affecting Nervous System > C264 - Anticonvulsant Agent
Ethyl 6-fluoro-1-methyl-4-oxo-7-(1-piprazinyl)-4H-[1,3]thiazeto[3,2-a]quinoline-3-carboxylate
C18H20FN3O3S (377.1209342000001)
(4-(N-(tert-Butyl)-N-(4-methoxybenzyl)sulfamoyl)phenyl)boronic acid
C18H24BNO5S (377.14681640000003)
4-[[2-methoxy-4-[(4-nitrophenyl)azo]phenyl]azo]phenol
C19H15N5O4 (377.11239900000004)
Pyridine, 4-(4-(4-fluorophenyl)-2-(5-((R)-methylsulfinyl)phenyl)-1H-imidazol-4-yl)-
Glufanide disodium
D006133 - Growth Substances > D043924 - Angiogenesis Modulating Agents D000970 - Antineoplastic Agents > D020533 - Angiogenesis Inhibitors D002317 - Cardiovascular Agents > D000889 - Anti-Arrhythmia Agents C274 - Antineoplastic Agent > C1742 - Angiogenesis Inhibitor D006133 - Growth Substances > D006131 - Growth Inhibitors D020011 - Protective Agents > D000931 - Antidotes C308 - Immunotherapeutic Agent D007155 - Immunologic Factors
Acridine half-mustard
D000970 - Antineoplastic Agents > D018906 - Antineoplastic Agents, Alkylating > D009588 - Nitrogen Mustard Compounds D009676 - Noxae > D009153 - Mutagens
6-(4-Hydroxyphenyl)-5-(4-methoxyphenyl)-1,3-dimethylpyrrolo[3,4-d]pyrimidine-2,4-dione
C21H19N3O4 (377.13754940000007)
2-(4-morpholinyl)-N-[(2-nitrophenyl)-oxomethyl]-4-thiazolecarbohydrazide
C15H15N5O5S (377.07938600000006)
Dasolampanel
C17H20ClN5O3 (377.1254600000001)
C78272 - Agent Affecting Nervous System > C47795 - CNS Stimulant
N-(2-methoxydibenzofuran-3-yl)-2-(4-methoxyphenoxy)acetamide
C22H19NO5 (377.12631640000006)
Ofloxacin N-oxide
C18H20FN3O5 (377.13869220000004)
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D024841 - Fluoroquinolones
Ethyl 2-amino-4-(4-chlorophenyl)-6-(hydroxymethyl)-8-oxo-4,8-dihydropyrano[3,2-b]pyran-3-carboxylate
C18H16ClNO6 (377.06661060000005)
4-benzyl-N-[4-(difluoromethoxy)phenyl]piperazine-1-carbothioamide
N-[3-chloro-4-(4-morpholinyl)phenyl]-1,1-dioxo-1,2-benzothiazol-3-amine
N-(1,3-benzodioxol-5-yl)-3-methyl-6-phenyl-2-imidazo[2,1-b]thiazolecarboxamide
C20H15N3O3S (377.0834080000001)
7-Pyridin-2-Yl-N-(3,4,5-Trimethoxyphenyl)-7h-Pyrrolo[2,3-D]pyrimidin-2-Amine
C20H19N5O3 (377.1487824000001)
[2-Amino-6-(2,6-difluoro-benzoyl)-imidazo[1,2-A]pyridin-3-YL]-phenyl-methanone
C21H13F2N3O2 (377.09757820000004)
6-Carbamimidoyl-4-(3-hydroxy-2-methyl-benzoylamino)-naphthalene-2-carboxylic acid methyl ester
C21H19N3O4 (377.13754940000007)
[4-({5-(Aminocarbonyl)-4-[(3-Methylphenyl)amino]pyrimidin-2-Yl}amino)phenyl]acetic Acid
C20H19N5O3 (377.1487824000001)
Phentolamine mesylate
C18H23N3O4S (377.14091980000006)
C78272 - Agent Affecting Nervous System > C29747 - Adrenergic Agent > C72900 - Adrenergic Antagonist D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents > D018674 - Adrenergic Antagonists D002317 - Cardiovascular Agents > D000959 - Antihypertensive Agents Phentolamine mesylate (Phentolamine methanesulfonate) is a reversible, non-selective, and orally active blocker of α1 and α2 adrenergic receptor that expands blood vessels to reduce peripheral vascular resistance. Phentolamine mesylate can be used for the research of pheochromocytoma-related hypertension, heart failure and erectile dysfunction[1][2][3].
Naltrexone Hydrochloride
C20H24ClNO4 (377.13937740000006)
D002492 - Central Nervous System Depressants > D009294 - Narcotics > D053610 - Opiate Alkaloids COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents D002491 - Central Nervous System Agents > D009292 - Narcotic Antagonists D002491 - Central Nervous System Agents > D000427 - Alcohol Deterrents C78272 - Agent Affecting Nervous System > C681 - Opiate Antagonist Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS
Lasmiditan
N - Nervous system > N02 - Analgesics > N02C - Antimigraine preparations > N02CC - Selective serotonin (5ht1) agonists D018377 - Neurotransmitter Agents > D018490 - Serotonin Agents > D017366 - Serotonin Receptor Agonists C78272 - Agent Affecting Nervous System > C47794 - Serotonin Agonist
Kinetin-7-N-glucoside
Kinetin-7-N-glucoside belongs to the class of organic compounds known as glycosylamines. Glycosylamines are compounds consisting of an amine with a beta-N-glycosidic bond to a carbohydrate, thus forming a cyclic hemiaminal ether bond (alpha-amino ether). Kinetin-7-N-glucoside is a strong basic compound (based on its pKa). Kinetin-7-N-glucoside is the product of the reaction between kinetin and UDP-D-glucose, with UDP as a co-product. The reaction is catalyzed by a UDP glycosyltransferase. Kinetin-7-N-glucoside is the product of the reaction between kinetin and UDP-D-glucose, with UDP as a co-product. The reaction is catalyzed by a UDP glycosyltransferase. [HMDB]
2-[(2-methyl-4-benzofuro[3,2-d]pyrimidinyl)thio]-N-(2-phenylethyl)acetamide
C21H19N3O2S (377.11979140000005)
3,4-Dimethyl-6-(6-nitro-1,3-benzodioxol-5-yl)-2-oxo-1,6-dihydropyrimidine-5-carboxylic acid propyl ester
1-[4-(3,4,5-Trimethoxyphenyl)-2-thiazolyl]-4-piperidinecarboxamide
C18H23N3O4S (377.14091980000006)
4-[(3,5-Dichloro-2-hydroxyphenyl)methylamino]-1,5-dimethyl-2-phenyl-3-pyrazolone
C18H17Cl2N3O2 (377.06977620000004)
4-allyl-1-anilino-6,7,8,9-tetrahydro[1]benzothieno[3,2-e][1,2,4]triazolo[4,3-a]pyrimidin-5(4H)-one
C20H19N5OS (377.13102440000006)
N-[[4-(dimethylsulfamoyl)anilino]-sulfanylidenemethyl]-2-phenylacetamide
4-benzyl-N-(3,5-dichlorophenyl)-1,4-diazepane-1-carboxamide
5-[(5-Tert-butyl-2,3-dimethylphenyl)sulfonylamino]-2-hydroxybenzoic acid
C19H23NO5S (377.12968680000006)
1-phenylspiro[1,3-diazinane-5,5-2,4,4a,6-tetrahydro-1H-[1,4]oxazino[4,3-a]quinoline]-2,4,6-trione
C21H19N3O4 (377.13754940000007)
8-chloro-N-(4-fluorophenyl)-2-(2-pyridinyl)-4-quinolinecarboxamide
C21H13ClFN3O (377.07311300000003)
N2-phenyl-6-[[(1-phenyl-5-tetrazolyl)thio]methyl]-1,3,5-triazine-2,4-diamine
C17H15N9S (377.11710700000003)
3-(2,5-dioxo-1-pyrrolidinyl)-N-(2-methyl-1,3-dioxo-5-isoindolyl)benzamide
C20H15N3O5 (377.10116600000003)
2-cyano-N-(2-furanylmethyl)-2-[3-(4-morpholinyl)-2-quinoxalinyl]acetamide
C20H19N5O3 (377.1487824000001)
N-ethyl-8-methyl-4-oxo-N-(phenylmethyl)-2-thieno[3,2-c][1]benzopyrancarboxamide
C22H19NO3S (377.1085584000001)
6-amino-5-cyano-2-(4-methoxyphenyl)-4-(3-pyridinyl)-4H-pyran-3-carboxylic acid ethyl ester
C21H19N3O4 (377.13754940000007)
3-(4-methylphenyl)-5-oxo-N-propyl-8-thiazolo[2,3-b]quinazolinecarboxamide
C21H19N3O2S (377.11979140000005)
2-[[2-Oxo-2-[4-[5-(trifluoromethyl)-2-pyridinyl]-1,4-diazepan-1-yl]ethyl]thio]acetic acid
C15H18F3N3O3S (377.10209140000006)
N-[(E)-[4-(2,3-Dichloroanilino)-4-oxobutan-2-ylidene]amino]-2-methylbenzamide
C18H17Cl2N3O2 (377.06977620000004)
1-[4-[4-[(5-Bromo-2-furanyl)methylamino]phenyl]-1-piperazinyl]ethanone
C17H20BrN3O2 (377.07388000000003)
(5E)-5-[[1-(4-chloro-2-fluorophenyl)-2,5-dimethylpyrrol-3-yl]methylidene]-3-methyl-2-methylimino-1,3-thiazolidin-4-one
C18H17ClFN3OS (377.07648340000003)
4-[(2E)-2-(2,4,5-trimethoxybenzylidene)hydrazinyl]-5H-pyrimido[5,4-b]indole
C20H19N5O3 (377.1487824000001)
2-(3,5-dimethylphenoxy)acetic acid [3-(1H-benzimidazol-2-yl)-3-cyano-2-oxopropyl] ester
C21H19N3O4 (377.13754940000007)
(2S)-2-[[(2-chlorophenyl)-oxomethyl]amino]-3-methylbutanoic acid (3-cyano-4-imino-2-oxopentyl) ester
C18H20ClN3O4 (377.1142270000001)
4,7-DI(Para-ethoxyphenyl)-1,2,5-thiadiazolo(3,4-C)pyridine
C21H19N3O2S (377.11979140000005)
2-(2-Trimethylsilyloxyethoxy)-4-quinolinecarboxylic acid trimethylsilyl ester
Adaptaquin
Adaptaquin is an inhibitor of hypoxia-inducible factor prolyl hydroxylase 2 (HIF-PHD2), with an IC50 of 2 μM. Adaptaquin can inhibit lipid peroxidation and maintain mitochondrial function[1][2].
CBiPES
C21H19N3O2S (377.11979140000005)
CBiPES is a potent mGlu2 positive allosteric modulator with an EC50 value of 92.8 nM. CBiPES attenuates stress-induced hyperthermia and Phencyclidine-induced hyperlocomotor activity. CBiPES can be used for research of neurological diseases[1][2].
CCT128930 (hydrochloride)
CCT128930 hydrochloride is a potent and selective inhibitor of AKT (IC50=6 nM). CCT128930 hydrochloride has 28-fold selectivity over the closely related PKA kinase (IC50=168 nM) through the targeting of Met282 of AKT (Met173 of PKA-AKT chimera), as well as 20-fold selectivity over p70S6K (IC50=120 nM). CCT128930 hydrochloride induces cell cycle arrest, DNA damage, and autophagy. Antitumor activity[1][2].
H3R antagonist 1 (hydrochloride)
H3R antagonist 1 hydrochloride is a histamine receptor 3 (H3R) inverse agonist extracted from patent WO2013107336A1, compound example 2.
mGluR2 antagonist 1
C21H16FN3O3 (377.11756379999997)
mGluR2 antagonist 1 is a highly potent, orally bioavailable and selective class of mGluR2 negative allosteric modulator (IC50 of 9 nM) with excellent brain permeability[1].
MLS-573151
C21H19N3O2S (377.11979140000005)
MLS-573151 (MLS000573151) is a selective GTPase Cdc42 inhibitor with an EC50 of 2 μM. MLS-573151 is inactive against other GTPases family members, such as Rab2, Rab7, H-Ras, Rac1, Rac 2 and RhoA wild-type. MLS-573151 acts by blocking the binding of GTP to Cdc42[1][2].
n-{2-[5-(4-hydroxyphenyl)-1-methyl-4,8-dioxo-7h-pyrrolo[3,2-f]indol-3-yl]ethyl}-n-methylformamide
C21H19N3O4 (377.13754940000007)
(2s,3r,4r,5r,6s)-2-({6-[(z)-(hydroxyimino)methyl]-[2,2'-bipyridin]-3-yl}oxy)-6-methyloxane-3,4,5-triol
2-[(23s)-24-methyl-5,7,18,20-tetraoxa-24-azahexacyclo[11.11.0.0²,¹⁰.0⁴,⁸.0¹⁴,²².0¹⁷,²¹]tetracosa-1(13),2,4(8),9,11,14,16,21-octaen-23-yl]ethanol
C22H19NO5 (377.12631640000006)