Exact Mass: 377.0715234

C19H13F2N7 (377.12004420000005)

JNJ-38877605

C274 - Antineoplastic Agent > C2189 - Signal Transduction Inhibitor > C129824 - Antineoplastic Protein Inhibitor C274 - Antineoplastic Agent > C163758 - Targeted Therapy Agent > C164000 - c-Met-targeting Agent C471 - Enzyme Inhibitor > C1404 - Protein Kinase Inhibitor > C1967 - Tyrosine Kinase Inhibitor C471 - Enzyme Inhibitor > C129825 - Antineoplastic Enzyme Inhibitor

KG-501

N-(4-Chlorophenyl)-3-(phosphonooxy)naphthalene-2-carboxamide

C17H13ClNO5P (377.02198480000004)

2-Hydroxypropyl glucosinolate

{[(e)-(3-hydroxy-1-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]sulphanyl}butylidene)amino]oxy}sulphonic acid

2-Hydroxypropyl glucosinolate is found in brassicas. 2-Hydroxypropyl glucosinolate is present in horseradish (Armoracia lapathifolia). Present in horseradish (Armoracia lapathifolia). 2-Hydroxypropyl glucosinolate is found in horseradish and brassicas.

4-(4-Fluorophenyl)-2-(4-methylsulfinylphenyl)-5-(4-pyridyl)-1H-imidazole

4-[4-(4-fluorophenyl)-2-(4-methanesulfinylphenyl)-1H-imidazol-5-yl]pyridine

C21H16FN3OS (377.0998058)

N-Hbgd

6-({[4-(hydroxymethyl)phenyl]methyl}[sulphanyl(carbonothioyl)]amino)hexane-1,2,3,4,5-pentol

C15H23NO6S2 (377.0966738)

S-Pyruvylglutathione

2-Amino-4-({1-[(carboxymethyl)-C-hydroxycarbonimidoyl]-2-[(2-oxopropanoyl)sulphanyl]ethyl}-C-hydroxycarbonimidoyl)butanoic acid

C13H19N3O8S (377.0892814)

3-Hydroxypropyl glucosinolate

RIT-D-2214

C13H19N3O6S2 (377.0715234)

7-Methyl-XMP

7-Methylguanosine 5-monophosphate

C11H16N5O6PS (377.05588860000006)

O1-(2-acetylamino-[1]naphthyl)-beta-D-glucopyranuronic acid|O1-(2-Acetylamino-[1]naphthyl)-beta-D-glucopyranuronsaeure

C18H19NO8 (377.1110614)

4-methoxyfuro[2,3-b]quinolin-7-yl beta-D-mannopyranoside|dictamnine-7-beta-D-mannopyranoside

C18H19NO8 (377.1110614)

S-methyl-5-thio-[3]adenylic acid|Thiomethyladenosin

Xenocladoniamide A

C20H12ClN3O3 (377.0567152)

O1-(6-acetylamino-[2]naphthyl)-beta-D-glucopyranuronic acid|O1-(6-Acetylamino-[2]naphthyl)-beta-D-glucopyranuronsaeure

C18H19NO8 (377.1110614)

Oxychelirubine

C21H15NO6 (377.08993300000003)

Sparoxomycin A1

C13H19N3O6S2 (377.0715234)

7-chloro-(2R)-2-O-beta-D-glucopyranosyl-4-hydroxy-2H-1,4-benzoxazin-3(4H)-one|7-Cl-DIBOA-Glc

C14H16ClNO9 (377.05135559999997)

Asp Asp Glu

Glu Asp Asp

C21H15NO6 (377.08993300000003)

SB 203580

4-[4-(4-fluorophenyl)-2-[4-methylsulfinyl)phenyl]-1H-imidazol-5-yl]-pyridine

C21H16FN3OS (377.0998058)

D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents D002491 - Central Nervous System Agents > D000700 - Analgesics D000893 - Anti-Inflammatory Agents D018501 - Antirheumatic Agents C308 - Immunotherapeutic Agent D004791 - Enzyme Inhibitors

12-Hydroxychelirubine

3-Hydroxypropyl-Glucosinolate

C19H17Cl2NO3 (377.05854320000003)

Acquisition and generation of the data is financially supported by the Max-Planck-Society

FR167356

Benzamide, 2,6-dichloro-N-(3-(1-hydroxy-1-methylethyl)-2-methyl-7-benzofuranyl)-

CONFIDENCE standard compound; INTERNAL_ID 245; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8799; ORIGINAL_PRECURSOR_SCAN_NO 8796 CONFIDENCE standard compound; INTERNAL_ID 245; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8818; ORIGINAL_PRECURSOR_SCAN_NO 8815 CONFIDENCE standard compound; INTERNAL_ID 245; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8849; ORIGINAL_PRECURSOR_SCAN_NO 8845 CONFIDENCE standard compound; INTERNAL_ID 245; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8855; ORIGINAL_PRECURSOR_SCAN_NO 8850 CONFIDENCE standard compound; INTERNAL_ID 245; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8828; ORIGINAL_PRECURSOR_SCAN_NO 8825 CONFIDENCE standard compound; INTERNAL_ID 245; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8869; ORIGINAL_PRECURSOR_SCAN_NO 8867

Asp Glu Asp

S-Pyruvylglutathione

C13H19N3O8S (377.0892814)

Asn-His-OH

(S)-2-(3-(2-amino-2-oxoethoxy)-4-nitrobenzamido)-4-(1H-imidazol-4-yl)butanoic acid

C15H15N5O7 (377.097144)

2-Hydroxypropyl glucosinolate

{[(E)-(3-hydroxy-1-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]sulfanyl}butylidene)amino]oxy}sulfonic acid

C18H16ClNO6 (377.06661060000005)

4-(2-Chlorophenyl)-5-methoxycabonyl-3-ethoxycarbonyl-6-methylpicolinic acid

Omeprazole Sulfone N-Oxide

C17H19N3O5S (377.10453640000003)

Fenthiaprop

C18H16ClNO4S (377.0488526000001)

disperse blue 124

2-[N-ethyl-4-[(5-nitrothiazol-2-yl)azo]-m-toluidino]ethyl acetate

C16H19N5O4S (377.11576940000003)

(4aR,8aR)-1-Bromo-3-methoxy-6-oxo-5,6,9,10-tetrahydro-4aH-[1]benz ofuro[3a,3,2-ef][2]benzazepine-11(12H)-carbaldehyde

C17H16BrNO4 (377.02626360000005)

N-BOC-2-BROMO-5-BENZYLOXYANILINE

C18H20BrNO3 (377.0626470000001)

Disperse Orange 29

C19H15N5O4 (377.11239900000004)

7-(4-BROMO-2,6-DIMETHYLPHENYL)-4-CHLORO-2,5,6-TRIMETHYL-7H-PYRROLO[2,3-D]PYRIMIDINE

C17H17BrClN3 (377.02942920000004)

5-nitrofluorescein

C20H11NO7 (377.0535496)

Scopine Di(2-thienyl) Glycolate

C18H19NO4S2 (377.0755454)

Benzenesulfonic acid,4-hydroxy-5-(2-hydroxy-4-methoxybenzoyl)-2-methoxy-, sodium salt (1:1)

C15H14NaO8S+ (377.03070640000004)

2-Carboxy-5-fluoro-1-[(1-naphthalenyl)methyl]-1H-indole-3-acetic acid

C22H16FNO4 (377.1063308)

UNII:S1199Y391N

C14H15N7O2S2 (377.072861)

2-BROMO-6-IODO-3-METHOXYPYRIDINE

C22H16FNO4 (377.1063308)

tert-Butyl 2-bromo-3-cyclohexyl-1H-indole-6-carboxylate

C19H24BrNO2 (377.0990304)

ethyl 2-[4-[(6-chlorobenzothiazol-2-yl)oxy]phenoxy]propionate

C18H16ClNO4S (377.0488526000001)

2H-Pyrrol-2-one, 4-acetyl-1-(4-bromophenyl)-5-cyclohexyl-1,5-dihydro-3-hydroxy-

C18H20BrNO3 (377.0626470000001)

Ronifibrate

3-[2-(4-chlorophenoxy)-2-methylpropanoyl]oxypropyl pyridine-3-carboxylate

C19H20ClNO5 (377.1029940000001)

C78276 - Agent Affecting Digestive System or Metabolism > C29703 - Antilipidemic Agent > C98150 - Fibrate Antilipidemic Agent C - Cardiovascular system > C10 - Lipid modifying agents > C10A - Lipid modifying agents, plain > C10AB - Fibrates

5-(4-TERT-BUTYLPHENYL)-4-[3-(TRIFLUOROMETHYL)PHENYL]-1,2,4-TRIAZOLE-3-THIOL

C19H18F3N3S (377.11734640000003)

4,4,4-Nitrilotribenzoic acid

C21H15NO6 (377.08993300000003)

ERRα antagonist-1

C21H19N3S2 (377.10203340000004)

1-PIPERIDINECARBOXYLIC ACID 4-(4-IODO-1H-PYRAZOL-1YL)-,1-1-DIMETHYLETHYLESTER

C13H20IN3O2 (377.060021)

Robenidine-d8 HCl

C15H6Cl3D8N5 (377.081690824)

Methyl 2-BroMo-3-(4-(2-(3-Methylpyridin-2-yl)ethoxy)phenyl)propanoate

C18H20BrNO3 (377.0626470000001)

5-Bromodescyano Citalopram

C19H21BrFNO (377.0790448)

Selurampanel

C16H19N5O4S (377.11576940000003)

C78272 - Agent Affecting Nervous System > C264 - Anticonvulsant Agent

Ethyl 6-fluoro-1-methyl-4-oxo-7-(1-piprazinyl)-4H-[1,3]thiazeto[3,2-a]quinoline-3-carboxylate

C18H20FN3O3S (377.1209342000001)

4-Nitrofluorescein

C20H11NO7 (377.0535496)

4-[[2-methoxy-4-[(4-nitrophenyl)azo]phenyl]azo]phenol

C19H15N5O4 (377.11239900000004)

Pyridine, 4-(4-(4-fluorophenyl)-2-(5-((R)-methylsulfinyl)phenyl)-1H-imidazol-4-yl)-

C21H16FN3OS (377.0998058)

Glufanide disodium

C16H17N3Na2O5 (377.0963552)

D006133 - Growth Substances > D043924 - Angiogenesis Modulating Agents D000970 - Antineoplastic Agents > D020533 - Angiogenesis Inhibitors D002317 - Cardiovascular Agents > D000889 - Anti-Arrhythmia Agents C274 - Antineoplastic Agent > C1742 - Angiogenesis Inhibitor D006133 - Growth Substances > D006131 - Growth Inhibitors D020011 - Protective Agents > D000931 - Antidotes C308 - Immunotherapeutic Agent D007155 - Immunologic Factors

Acridine half-mustard

C19H21Cl2N3O (377.1061596)

D000970 - Antineoplastic Agents > D018906 - Antineoplastic Agents, Alkylating > D009588 - Nitrogen Mustard Compounds D009676 - Noxae > D009153 - Mutagens

COX-2 Inhibitor I

C18H16ClNO4S (377.0488526000001)

2-(4-morpholinyl)-N-[(2-nitrophenyl)-oxomethyl]-4-thiazolecarbohydrazide

C15H15N5O5S (377.07938600000006)

2-O-Methylguanosine 5-monophosphate

C14H20BrNO4S (377.0296340000001)

1-(4-Bromo-2,5-dimethoxyphenyl)sulfonylazepane

1-Methylguanosine 5-(dihydrogen phosphate)

C18H16ClNO6 (377.06661060000005)

Ethyl 2-amino-4-(4-chlorophenyl)-6-(hydroxymethyl)-8-oxo-4,8-dihydropyrano[3,2-b]pyran-3-carboxylate

N-[3-chloro-4-(4-morpholinyl)phenyl]-1,1-dioxo-1,2-benzothiazol-3-amine

C17H16ClN3O3S (377.0600856)

N-(1,3-benzodioxol-5-yl)-3-methyl-6-phenyl-2-imidazo[2,1-b]thiazolecarboxamide

C20H15N3O3S (377.0834080000001)

2-(3-((4,5,7-trifluorobenzo[d]thiazol-2-yl)methyl)-1H-pyrrolo[2,3-b]pyridin-1-yl)acetic acid

C17H10F3N3O2S (377.0445796)

[2-Amino-6-(2,6-difluoro-benzoyl)-imidazo[1,2-A]pyridin-3-YL]-phenyl-methanone

C21H13F2N3O2 (377.09757820000004)

7,8-Dihydro-8-oxo-guanosine 5-phosphate

C10H12N5O9P-2 (377.03726320000004)

N2-hydroxyguanosine 5-monophosphate

C10H12N5O9P-2 (377.03726320000004)

4,5-Dihydrofarnesyl diphosphate

C15H23O7P2-3 (377.0918968)

[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl] (1E)-4-hydroxy-N-sulfooxybutanimidothioate

S-lactoylgluta-thione

C13H19N3O8S (377.0892814)

2-[(2-methyl-4-benzofuro[3,2-d]pyrimidinyl)thio]-N-(2-phenylethyl)acetamide

Glu-Asp-Asp

C18H17Cl2N3O2 (377.06977620000004)

4-[(3,5-Dichloro-2-hydroxyphenyl)methylamino]-1,5-dimethyl-2-phenyl-3-pyrazolone

N-[[4-(dimethylsulfamoyl)anilino]-sulfanylidenemethyl]-2-phenylacetamide

C17H19N3O3S2 (377.0867784)

N(7)-methylguanosine 5-phosphate

4-benzyl-N-(3,5-dichlorophenyl)-1,4-diazepane-1-carboxamide

C19H21Cl2N3O (377.1061596)

1,3-Benzodioxol-5-yl 4-(diethylsulfamoyl)benzoate

C18H19NO6S (377.0933034)

N(2)-methylguanosine 5-monophosphate

C21H13ClFN3O (377.07311300000003)

8-chloro-N-(4-fluorophenyl)-2-(2-pyridinyl)-4-quinolinecarboxamide

N-(7-bromo-3,4-dihydro-2H-1,5-benzodioxepin-8-yl)-3-methoxybenzamide

C17H16BrNO4 (377.02626360000005)

N2-phenyl-6-[[(1-phenyl-5-tetrazolyl)thio]methyl]-1,3,5-triazine-2,4-diamine

C17H15N9S (377.11710700000003)

3-(2,5-dioxo-1-pyrrolidinyl)-N-(2-methyl-1,3-dioxo-5-isoindolyl)benzamide

C20H15N3O5 (377.10116600000003)

N-ethyl-8-methyl-4-oxo-N-(phenylmethyl)-2-thieno[3,2-c][1]benzopyrancarboxamide

C22H19NO3S (377.1085584000001)

3-(4-methylphenyl)-5-oxo-N-propyl-8-thiazolo[2,3-b]quinazolinecarboxamide

C15H18F3N3O3S (377.10209140000006)

2-[[2-Oxo-2-[4-[5-(trifluoromethyl)-2-pyridinyl]-1,4-diazepan-1-yl]ethyl]thio]acetic acid

N-[(E)-[4-(2,3-Dichloroanilino)-4-oxobutan-2-ylidene]amino]-2-methylbenzamide

C18H17Cl2N3O2 (377.06977620000004)

1-[4-[4-[(5-Bromo-2-furanyl)methylamino]phenyl]-1-piperazinyl]ethanone

C17H20BrN3O2 (377.07388000000003)

Asp-Glu-Asp

Asp-Asp-Glu

C18H17ClFN3OS (377.07648340000003)

(5E)-5-[[1-(4-chloro-2-fluorophenyl)-2,5-dimethylpyrrol-3-yl]methylidene]-3-methyl-2-methylimino-1,3-thiazolidin-4-one

Propicillin(1-)

C18H21N2O5S- (377.11711160000004)

(2S)-2-[[(2-chlorophenyl)-oxomethyl]amino]-3-methylbutanoic acid (3-cyano-4-imino-2-oxopentyl) ester

C18H20ClN3O4 (377.1142270000001)

2-[(3,4,8,9,10-Pentahydroxy-6-oxobenzo[c]chromene-1-carbonyl)amino]acetic acid

C16H11NO10 (377.0382946)

4,7-DI(Para-ethoxyphenyl)-1,2,5-thiadiazolo(3,4-C)pyridine

Adaptaquin

C21H16ClN3O2 (377.0930986)

Adaptaquin is an inhibitor of hypoxia-inducible factor prolyl hydroxylase 2 (HIF-PHD2), with an IC50 of 2 μM. Adaptaquin can inhibit lipid peroxidation and maintain mitochondrial function[1][2].

CBiPES

C21H16FN3O3 (377.11756379999997)

CBiPES is a potent mGlu2 positive allosteric modulator with an EC50 value of 92.8 nM. CBiPES attenuates stress-induced hyperthermia and Phencyclidine-induced hyperlocomotor activity. CBiPES can be used for research of neurological diseases[1][2].

CCT128930 (hydrochloride)

C18H21Cl2N5 (377.1173926)

CCT128930 hydrochloride is a potent and selective inhibitor of AKT (IC50=6 nM). CCT128930 hydrochloride has 28-fold selectivity over the closely related PKA kinase (IC50=168 nM) through the targeting of Met282 of AKT (Met173 of PKA-AKT chimera), as well as 20-fold selectivity over p70S6K (IC50=120 nM). CCT128930 hydrochloride induces cell cycle arrest, DNA damage, and autophagy. Antitumor activity[1][2].

mGluR2 antagonist 1

mGluR2 antagonist 1 is a highly potent, orally bioavailable and selective class of mGluR2 negative allosteric modulator (IC50 of 9 nM) with excellent brain permeability[1].

MLS-573151