Exact Mass: 377.07648340000003
Exact Mass Matches: 377.07648340000003
Found 150 metabolites which its exact mass value is equals to given mass value 377.07648340000003,
within given mass tolerance error 0.05 dalton. Try search metabolite list with more accurate mass tolerance error
0.01 dalton.
6-(2-Hydroxyethyl)-5,6-dihydrosanguinarine
C22H19NO5 (377.12631640000006)
JNJ-38877605
C19H13F2N7 (377.12004420000005)
C274 - Antineoplastic Agent > C2189 - Signal Transduction Inhibitor > C129824 - Antineoplastic Protein Inhibitor C274 - Antineoplastic Agent > C163758 - Targeted Therapy Agent > C164000 - c-Met-targeting Agent C471 - Enzyme Inhibitor > C1404 - Protein Kinase Inhibitor > C1967 - Tyrosine Kinase Inhibitor C471 - Enzyme Inhibitor > C129825 - Antineoplastic Enzyme Inhibitor
2-Hydroxypropyl glucosinolate
2-Hydroxypropyl glucosinolate is found in brassicas. 2-Hydroxypropyl glucosinolate is present in horseradish (Armoracia lapathifolia). Present in horseradish (Armoracia lapathifolia). 2-Hydroxypropyl glucosinolate is found in horseradish and brassicas.
S-(2-Hydroxy-3-buten-1-yl)glutathione
4-(4-Fluorophenyl)-2-(4-methylsulfinylphenyl)-5-(4-pyridyl)-1H-imidazole
(2S)-2-(Butanoylamino)-5-[[(1R)-2-(carboxymethylamino)-2-oxo-1-(sulfanylmethyl)ethyl]amino]-5-oxo-pentanoic acid
S-Pyruvylglutathione
Ethoxysanguinarine
C22H19NO5 (377.12631640000006)
Ethoxysanguinarine is a benzophenanthridine alkaloid natural product that is mainly found in Macleaya cordata. Ethoxysanguinarine is an inhibitor of protein phosphatase 2A (CIP2A). Ethoxysanguinarine induces cell apoptosis and inhibits colorectal cancer cells growth[1]. Ethoxysanguinarine is a benzophenanthridine alkaloid natural product that is mainly found in Macleaya cordata. Ethoxysanguinarine is an inhibitor of protein phosphatase 2A (CIP2A). Ethoxysanguinarine induces cell apoptosis and inhibits colorectal cancer cells growth[1].
Piscerythoxazole
C22H19NO5 (377.12631640000006)
L-gamma-glutamyl-S-3-(1-oxobutyl)-L-cysteinyl-glycine
This record was created by the financial support of MEXT/JSPS KAKENHI Grant Number 16HP2005 to the Mass Spectrometry Society of Japan.
O1-(2-acetylamino-[1]naphthyl)-beta-D-glucopyranuronic acid|O1-(2-Acetylamino-[1]naphthyl)-beta-D-glucopyranuronsaeure
4-methoxyfuro[2,3-b]quinolin-7-yl beta-D-mannopyranoside|dictamnine-7-beta-D-mannopyranoside
S-methyl-5-thio-[3]adenylic acid|Thiomethyladenosin
C11H16N5O6PS (377.05588860000006)
(2-hydroxy-1-methoxy-12-methyl-12,13-dihydro-[1,3]dioxolo[4,5:4,5]benzo[1,2-c]phenanthridin-13-yl)-acetaldehyde|11-(Formyl-methylenyl)-O-desmethyl-dihydrochelerythrin
C22H19NO5 (377.12631640000006)
O1-(6-acetylamino-[2]naphthyl)-beta-D-glucopyranuronic acid|O1-(6-Acetylamino-[2]naphthyl)-beta-D-glucopyranuronsaeure
14-Ethoxy-13-methyl-13,14-dihydro-[1,3]dioxolo[4,5:4,5]benzo[1,2-c][1,3]dioxolo[4,5-i]phenanthridine
C22H19NO5 (377.12631640000006)
7-chloro-(2R)-2-O-beta-D-glucopyranosyl-4-hydroxy-2H-1,4-benzoxazin-3(4H)-one|7-Cl-DIBOA-Glc
C14H16ClNO9 (377.05135559999997)
SB 203580
D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents D002491 - Central Nervous System Agents > D000700 - Analgesics D000893 - Anti-Inflammatory Agents D018501 - Antirheumatic Agents C308 - Immunotherapeutic Agent D004791 - Enzyme Inhibitors
3-Hydroxypropyl-Glucosinolate
Acquisition and generation of the data is financially supported by the Max-Planck-Society
FR167356
C19H17Cl2NO3 (377.05854320000003)
CONFIDENCE standard compound; INTERNAL_ID 245; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8799; ORIGINAL_PRECURSOR_SCAN_NO 8796 CONFIDENCE standard compound; INTERNAL_ID 245; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8818; ORIGINAL_PRECURSOR_SCAN_NO 8815 CONFIDENCE standard compound; INTERNAL_ID 245; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8849; ORIGINAL_PRECURSOR_SCAN_NO 8845 CONFIDENCE standard compound; INTERNAL_ID 245; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8855; ORIGINAL_PRECURSOR_SCAN_NO 8850 CONFIDENCE standard compound; INTERNAL_ID 245; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8828; ORIGINAL_PRECURSOR_SCAN_NO 8825 CONFIDENCE standard compound; INTERNAL_ID 245; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8869; ORIGINAL_PRECURSOR_SCAN_NO 8867
2-Hydroxypropyl glucosinolate
4-(2-Chlorophenyl)-5-methoxycabonyl-3-ethoxycarbonyl-6-methylpicolinic acid
C18H16ClNO6 (377.06661060000005)
3-[[2-(4-phenylmethoxyphenoxy)acetyl]amino]benzoic acid
C22H19NO5 (377.12631640000006)
disperse blue 124
C16H19N5O4S (377.11576940000003)
7-(4-BROMO-2,6-DIMETHYLPHENYL)-4-CHLORO-2,5,6-TRIMETHYL-7H-PYRROLO[2,3-D]PYRIMIDINE
C17H17BrClN3 (377.02942920000004)
Benzenesulfonic acid,4-hydroxy-5-(2-hydroxy-4-methoxybenzoyl)-2-methoxy-, sodium salt (1:1)
C15H14NaO8S+ (377.03070640000004)
2-Carboxy-5-fluoro-1-[(1-naphthalenyl)methyl]-1H-indole-3-acetic acid
tert-Butyl 2-bromo-3-cyclohexyl-1H-indole-6-carboxylate
ethyl 2-[4-[(6-chlorobenzothiazol-2-yl)oxy]phenoxy]propionate
C18H16ClNO4S (377.0488526000001)
2H-Pyrrol-2-one, 4-acetyl-1-(4-bromophenyl)-5-cyclohexyl-1,5-dihydro-3-hydroxy-
C18H20BrNO3 (377.0626470000001)
Ronifibrate
C19H20ClNO5 (377.1029940000001)
C78276 - Agent Affecting Digestive System or Metabolism > C29703 - Antilipidemic Agent > C98150 - Fibrate Antilipidemic Agent C - Cardiovascular system > C10 - Lipid modifying agents > C10A - Lipid modifying agents, plain > C10AB - Fibrates
5-(4-TERT-BUTYLPHENYL)-4-[3-(TRIFLUOROMETHYL)PHENYL]-1,2,4-TRIAZOLE-3-THIOL
C19H18F3N3S (377.11734640000003)
1-PIPERIDINECARBOXYLIC ACID 4-(4-IODO-1H-PYRAZOL-1YL)-,1-1-DIMETHYLETHYLESTER
1,2-di-o-acetyl-3-azido-3-deoxy-5-o-toluoyl-d-ribofuranose
Methyl 2-BroMo-3-(4-(2-(3-Methylpyridin-2-yl)ethoxy)phenyl)propanoate
C18H20BrNO3 (377.0626470000001)
Selurampanel
C16H19N5O4S (377.11576940000003)
C78272 - Agent Affecting Nervous System > C264 - Anticonvulsant Agent
Ethyl 6-fluoro-1-methyl-4-oxo-7-(1-piprazinyl)-4H-[1,3]thiazeto[3,2-a]quinoline-3-carboxylate
C18H20FN3O3S (377.1209342000001)
4-[[2-methoxy-4-[(4-nitrophenyl)azo]phenyl]azo]phenol
C19H15N5O4 (377.11239900000004)
Pyridine, 4-(4-(4-fluorophenyl)-2-(5-((R)-methylsulfinyl)phenyl)-1H-imidazol-4-yl)-
Glufanide disodium
D006133 - Growth Substances > D043924 - Angiogenesis Modulating Agents D000970 - Antineoplastic Agents > D020533 - Angiogenesis Inhibitors D002317 - Cardiovascular Agents > D000889 - Anti-Arrhythmia Agents C274 - Antineoplastic Agent > C1742 - Angiogenesis Inhibitor D006133 - Growth Substances > D006131 - Growth Inhibitors D020011 - Protective Agents > D000931 - Antidotes C308 - Immunotherapeutic Agent D007155 - Immunologic Factors
Acridine half-mustard
D000970 - Antineoplastic Agents > D018906 - Antineoplastic Agents, Alkylating > D009588 - Nitrogen Mustard Compounds D009676 - Noxae > D009153 - Mutagens
2-(4-morpholinyl)-N-[(2-nitrophenyl)-oxomethyl]-4-thiazolecarbohydrazide
C15H15N5O5S (377.07938600000006)
Dasolampanel
C17H20ClN5O3 (377.1254600000001)
C78272 - Agent Affecting Nervous System > C47795 - CNS Stimulant
1-(4-Bromo-2,5-dimethoxyphenyl)sulfonylazepane
C14H20BrNO4S (377.0296340000001)
N-(2-methoxydibenzofuran-3-yl)-2-(4-methoxyphenoxy)acetamide
C22H19NO5 (377.12631640000006)
Ethyl 2-amino-4-(4-chlorophenyl)-6-(hydroxymethyl)-8-oxo-4,8-dihydropyrano[3,2-b]pyran-3-carboxylate
C18H16ClNO6 (377.06661060000005)
N-[3-chloro-4-(4-morpholinyl)phenyl]-1,1-dioxo-1,2-benzothiazol-3-amine
N-(1,3-benzodioxol-5-yl)-3-methyl-6-phenyl-2-imidazo[2,1-b]thiazolecarboxamide
C20H15N3O3S (377.0834080000001)
2-(3-((4,5,7-trifluorobenzo[d]thiazol-2-yl)methyl)-1H-pyrrolo[2,3-b]pyridin-1-yl)acetic acid
[2-Amino-6-(2,6-difluoro-benzoyl)-imidazo[1,2-A]pyridin-3-YL]-phenyl-methanone
C21H13F2N3O2 (377.09757820000004)
7,8-Dihydro-8-oxo-guanosine 5-phosphate
C10H12N5O9P-2 (377.03726320000004)
N2-hydroxyguanosine 5-monophosphate
C10H12N5O9P-2 (377.03726320000004)
[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl] (1E)-4-hydroxy-N-sulfooxybutanimidothioate
2-[(2-methyl-4-benzofuro[3,2-d]pyrimidinyl)thio]-N-(2-phenylethyl)acetamide
C21H19N3O2S (377.11979140000005)
3,4-Dimethyl-6-(6-nitro-1,3-benzodioxol-5-yl)-2-oxo-1,6-dihydropyrimidine-5-carboxylic acid propyl ester
4-[(3,5-Dichloro-2-hydroxyphenyl)methylamino]-1,5-dimethyl-2-phenyl-3-pyrazolone
C18H17Cl2N3O2 (377.06977620000004)
N-[[4-(dimethylsulfamoyl)anilino]-sulfanylidenemethyl]-2-phenylacetamide
4-benzyl-N-(3,5-dichlorophenyl)-1,4-diazepane-1-carboxamide
8-chloro-N-(4-fluorophenyl)-2-(2-pyridinyl)-4-quinolinecarboxamide
C21H13ClFN3O (377.07311300000003)
N2-phenyl-6-[[(1-phenyl-5-tetrazolyl)thio]methyl]-1,3,5-triazine-2,4-diamine
C17H15N9S (377.11710700000003)
3-(2,5-dioxo-1-pyrrolidinyl)-N-(2-methyl-1,3-dioxo-5-isoindolyl)benzamide
C20H15N3O5 (377.10116600000003)
N-ethyl-8-methyl-4-oxo-N-(phenylmethyl)-2-thieno[3,2-c][1]benzopyrancarboxamide
C22H19NO3S (377.1085584000001)
3-(4-methylphenyl)-5-oxo-N-propyl-8-thiazolo[2,3-b]quinazolinecarboxamide
C21H19N3O2S (377.11979140000005)
2-[[2-Oxo-2-[4-[5-(trifluoromethyl)-2-pyridinyl]-1,4-diazepan-1-yl]ethyl]thio]acetic acid
C15H18F3N3O3S (377.10209140000006)
N-[(E)-[4-(2,3-Dichloroanilino)-4-oxobutan-2-ylidene]amino]-2-methylbenzamide
C18H17Cl2N3O2 (377.06977620000004)
1-[4-[4-[(5-Bromo-2-furanyl)methylamino]phenyl]-1-piperazinyl]ethanone
C17H20BrN3O2 (377.07388000000003)
(5E)-5-[[1-(4-chloro-2-fluorophenyl)-2,5-dimethylpyrrol-3-yl]methylidene]-3-methyl-2-methylimino-1,3-thiazolidin-4-one
C18H17ClFN3OS (377.07648340000003)
(2S)-2-[[(2-chlorophenyl)-oxomethyl]amino]-3-methylbutanoic acid (3-cyano-4-imino-2-oxopentyl) ester
C18H20ClN3O4 (377.1142270000001)
2-[(3,4,8,9,10-Pentahydroxy-6-oxobenzo[c]chromene-1-carbonyl)amino]acetic acid
4,7-DI(Para-ethoxyphenyl)-1,2,5-thiadiazolo(3,4-C)pyridine
C21H19N3O2S (377.11979140000005)
Adaptaquin
Adaptaquin is an inhibitor of hypoxia-inducible factor prolyl hydroxylase 2 (HIF-PHD2), with an IC50 of 2 μM. Adaptaquin can inhibit lipid peroxidation and maintain mitochondrial function[1][2].
CBiPES
C21H19N3O2S (377.11979140000005)
CBiPES is a potent mGlu2 positive allosteric modulator with an EC50 value of 92.8 nM. CBiPES attenuates stress-induced hyperthermia and Phencyclidine-induced hyperlocomotor activity. CBiPES can be used for research of neurological diseases[1][2].
CCT128930 (hydrochloride)
CCT128930 hydrochloride is a potent and selective inhibitor of AKT (IC50=6 nM). CCT128930 hydrochloride has 28-fold selectivity over the closely related PKA kinase (IC50=168 nM) through the targeting of Met282 of AKT (Met173 of PKA-AKT chimera), as well as 20-fold selectivity over p70S6K (IC50=120 nM). CCT128930 hydrochloride induces cell cycle arrest, DNA damage, and autophagy. Antitumor activity[1][2].
mGluR2 antagonist 1
C21H16FN3O3 (377.11756379999997)
mGluR2 antagonist 1 is a highly potent, orally bioavailable and selective class of mGluR2 negative allosteric modulator (IC50 of 9 nM) with excellent brain permeability[1].
MLS-573151
C21H19N3O2S (377.11979140000005)
MLS-573151 (MLS000573151) is a selective GTPase Cdc42 inhibitor with an EC50 of 2 μM. MLS-573151 is inactive against other GTPases family members, such as Rab2, Rab7, H-Ras, Rac1, Rac 2 and RhoA wild-type. MLS-573151 acts by blocking the binding of GTP to Cdc42[1][2].
(2s,3r,4r,5r,6s)-2-({6-[(z)-(hydroxyimino)methyl]-[2,2'-bipyridin]-3-yl}oxy)-6-methyloxane-3,4,5-triol
2-[(23s)-24-methyl-5,7,18,20-tetraoxa-24-azahexacyclo[11.11.0.0²,¹⁰.0⁴,⁸.0¹⁴,²².0¹⁷,²¹]tetracosa-1(13),2,4(8),9,11,14,16,21-octaen-23-yl]ethanol
C22H19NO5 (377.12631640000006)
(2e)-3-(2,4-dihydroxy-6-methylpyrimidin-5-yl)-n-[(2s)-1-hydroxy-3-[(r)-(r)-methanesulfinylmethanesulfinyl]propan-2-yl]prop-2-enimidic acid
7-cl-diboa-glc
C14H16ClNO9 (377.05135559999997)
{"Ingredient_id": "HBIN013138","Ingredient_name": "7-cl-diboa-glc","Alias": "NA","Ingredient_formula": "C14H16ClNO9","Ingredient_Smile": "C1=CC2=C(C=C1Cl)OC(C(=O)N2O)OC3C(C(C(C(O3)CO)O)O)O","Ingredient_weight": "NA","OB_score": "NA","CAS_id": "NA","SymMap_id": "NA","TCMID_id": "3815","TCMSP_id": "NA","TCM_ID_id": "NA","PubChem_id": "NA","DrugBank_id": "NA"}
n-(2-hydroxy-5-{[8-(hydroxymethyl)-3-oxophenoxazin-2-yl]amino}phenyl)carboximidic acid
C20H15N3O5 (377.10116600000003)
(2e)-3-(2,4-dihydroxy-6-methylpyrimidin-5-yl)-n-[(2s)-1-hydroxy-3-[(r)-(s)-methanesulfinylmethanesulfinyl]propan-2-yl]prop-2-enimidic acid
(2r,3r,4s,5s,6r)-2-({6-[(z)-(hydroxyimino)methyl]-[2,2'-bipyridin]-3-yl}oxy)-6-methyloxane-3,4,5-triol
methyl 3-{4-acetyl-5-hydroxy-8-methylphenanthro[3,4-d][1,3]oxazol-2-yl}propanoate
C22H19NO5 (377.12631640000006)
2-({6-[(hydroxyimino)methyl]-[2,2'-bipyridin]-3-yl}oxy)-6-methyloxane-3,4,5-triol
2-(4-{6-chloro-3h-pyrrolo[2,3-c]quinolin-4-yl}-1,3-thiazol-2-yl)phenol
7-chloro-4-hydroxy-2-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-2h-1,4-benzoxazin-3-one
C14H16ClNO9 (377.05135559999997)
2-(hydroxymethyl)-6-({4-methoxyfuro[2,3-b]quinolin-7-yl}oxy)oxane-3,4,5-triol
7-(diethylamino)-3-(5-phenyl-1,3,4-thiadiazol-2-yl)chromen-2-one
C21H19N3O2S (377.11979140000005)
(2r,3s,4s,5s,6s)-2-(hydroxymethyl)-6-({4-methoxyfuro[2,3-b]quinolin-7-yl}oxy)oxane-3,4,5-triol
(2s,5r,6r)-6-[(2-{[(2s)-2-amino-2-carboxyethyl]sulfanyl}-1-hydroxyethylidene)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
2-(4-{1-chloro-3h-pyrrolo[2,3-c]quinolin-4-yl}-1,3-thiazol-2-yl)phenol
7-hydroxy-3-[4-methoxy-7-(3-methylbut-2-en-1-yl)-1,3-benzoxazol-6-yl]chromen-4-one
C22H19NO5 (377.12631640000006)
6-({2-[(2-amino-2-carboxyethyl)sulfanyl]-1-hydroxyethylidene}amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
11'-hydroxy-2-(2-hydroxyethyl)-7-methoxy-6'-methyl-3'-oxaspiro[isoindole-1,2'-tricyclo[6.3.1.0⁴,¹²]dodecane]-1'(12'),4',6',8',10'-pentaen-3-one
C22H19NO5 (377.12631640000006)
4-[5-(4-fluorophenyl)-2-(4-methanesulfinylphenyl)-1h-imidazol-4-yl]pyridine
(2r)-7-chloro-4-hydroxy-2-{[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-2h-1,4-benzoxazin-3-one
C14H16ClNO9 (377.05135559999997)
(3r,6r)-3-(1h-indol-3-ylmethyl)-6-isopropyl-3,6-bis(methylsulfanyl)pyrazine-2,5-diol
2-{24-methyl-5,7,18,20-tetraoxa-24-azahexacyclo[11.11.0.0²,¹⁰.0⁴,⁸.0¹⁴,²².0¹⁷,²¹]tetracosa-1(13),2,4(8),9,11,14,16,21-octaen-23-yl}ethanol
C22H19NO5 (377.12631640000006)