Exact Mass: 372.1572804
Exact Mass Matches: 372.1572804
Found 500 metabolites which its exact mass value is equals to given mass value 372.1572804,
within given mass tolerance error 0.05 dalton. Try search metabolite list with more accurate mass tolerance error
0.01 dalton.
Syringin
Syringin is a monosaccharide derivative that is trans-sinapyl alcohol attached to a beta-D-glucopyranosyl residue at position 1 via a glycosidic linkage. It has a role as a hepatoprotective agent and a plant metabolite. It is a beta-D-glucoside, a monosaccharide derivative, a primary alcohol and a dimethoxybenzene. It is functionally related to a trans-sinapyl alcohol. Syringin is a natural product found in Salacia chinensis, Codonopsis lanceolata, and other organisms with data available. See also: Codonopsis pilosula root (part of). A monosaccharide derivative that is trans-sinapyl alcohol attached to a beta-D-glucopyranosyl residue at position 1 via a glycosidic linkage. Syringin is a main bioactive phenolic glycoside in Acanthopanax senticosus, with anti-osteoporosis activity. Syringin prevents cardiac hypertrophy induced by pressure overload through the attenuation of autophagy[1][2]. Syringin is a main bioactive phenolic glycoside in Acanthopanax senticosus, with anti-osteoporosis activity. Syringin prevents cardiac hypertrophy induced by pressure overload through the attenuation of autophagy[1][2].
Fargesone A
Fargesone A is a member of benzodioxoles. Fargesone A is a natural product found in Piper wightii, Piper hymenophyllum, and other organisms with data available.
Biocytin
C16H28N4O4S (372.18311680000005)
Biocytin is a naturally occurring low molecular weight analog of biotin, and a primary source of this essential metabolite for mammals. Biotinidase acts as a hydrolase by cleaving biocytin and biotinyl-peptides, thereby liberating biotin for reutilization. Mammals cannot synthesize biotin and, therefore, derive the vitamin from dietary sources or from the endogenous turnover of the carboxylases. Free biotin can readily enter the biotin pool, whereas holocarboxylases or other biotin-containing proteins must first be degraded proteolytically to biocytin (biotinyl-e-lysine) or biotinyl-peptides. Biocytin is also an especially versatile marker for neuroanatomical investigations, shown that may have multiple applications, especially for labeling neurons. (PMID: 8930409, 1384763, 2479450) [HMDB] Biocytin is a naturally occurring low molecular weight analog of biotin, and a primary source of this essential metabolite for mammals. Biotinidase acts as a hydrolase by cleaving biocytin and biotinyl-peptides, thereby liberating biotin for reutilization. Mammals cannot synthesize biotin and, therefore, derive the vitamin from dietary sources or from the endogenous turnover of the carboxylases. Free biotin can readily enter the biotin pool, whereas holocarboxylases or other biotin-containing proteins must first be degraded proteolytically to biocytin (biotinyl-e-lysine) or biotinyl-peptides. Biocytin is also an especially versatile marker for neuroanatomical investigations, shown that may have multiple applications, especially for labeling neurons. (PMID:8930409, 1384763, 2479450).
Tangeritin
Isolated from tangerine peel and Fortunella japonica (round kumquat). Potential nutriceutical. Tangeritin is found in many foods, some of which are apple, broccoli, sweet bay, and tea. Tangeritin is found in apple. Tangeritin is isolated from tangerine peel and Fortunella japonica (round kumquat). Potential nutriceutica Tangeretin (Tangeritin), a flavonoid from citrus fruit peels, has been proven to play an important role in anti-inflammatory responses and neuroprotective effects in several disease models, and is a Notch-1 inhibitor. Tangeretin (Tangeritin), a flavonoid from citrus fruit peels, has been proven to play an important role in anti-inflammatory responses and neuroprotective effects in several disease models, and is a Notch-1 inhibitor.
(-)-Arctigenin
(-)-Arctigenin is found in burdock. (-)-Arctigenin is isolated from Cnicus benedictus, Forsythia viridissima, Arctium lappa, Ipomoea cairica and others (CCD).Arctigenin is a lignan found in certain plants of the Asteraceae , including the Greater burdock (Arctium lappa) and Saussurea heteromalla. It has shown antiviral and anticancer effects. It is the aglycone of arctiin. (Wikipedia (-)-Arctigenin is a lignan. Arctigenin is a natural product found in Centaurea cineraria, Forsythia suspensa, and other organisms with data available. See also: Arctium lappa Root (part of); Arctium lappa fruit (part of); Pumpkin Seed (part of) ... View More ... Isolated from Cnicus benedictus, Forsythia viridissima, Arctium lappa, Ipomoea cairica and others (CCD) Arctigenin ((-)-Arctigenin), a biologically active lignan, can be used as an antitumor agent. Arctigenin exhibits potent antioxidant, anti-inflammatory and antiviral (influenza A virus) activities. Arctigenin can be used for the research of metabolic disorders, and central nervous system dysfunctions[1][2][3]. Arctigenin ((-)-Arctigenin), a biologically active lignan, can be used as an antitumor agent. Arctigenin exhibits potent antioxidant, anti-inflammatory and antiviral (influenza A virus) activities. Arctigenin can be used for the research of metabolic disorders, and central nervous system dysfunctions[1][2][3].
Kadsurin A
Sinensetin
Sinensetin is a pentamethoxyflavone that is flavone substituted by methoxy groups at positions 5, 6, 7, 3 and 4 respectively. It has a role as a plant metabolite. It is functionally related to a flavone. Sinensetin is a natural product found in Citrus tankan, Citrus keraji, and other organisms with data available. See also: Tangerine peel (part of); Citrus aurantium fruit rind (part of). A pentamethoxyflavone that is flavone substituted by methoxy groups at positions 5, 6, 7, 3 and 4 respectively. Sinensetin is found in citrus. Sinensetin is found in orange peel and other plant sources. Found in orange peel and other plant sources Sinensetin is a methylated flavonoid found in fruits that has strong anti-vascular and anti-inflammatory properties. Sinensetin is a methylated flavonoid found in fruits that has strong anti-vascular and anti-inflammatory properties.
Sesamolinol
Sesamolinol is found in cereals and cereal products. Sesamolinol is isolated from sesame seeds (Sesamum indicum). Isolated from sesame seeds (Sesamum indicum). Sesamolinol is found in cereals and cereal products and sesame.
Buthiobate
D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents > D007096 - Imidoesters
Averantin
A tetrahydroxyanthraquinone that is 1,3,6,8-tetrahydroxy-9,10-anthraquinone bearing a 1-hydroxyhexyl substituent at position 2.
Acebutolol HCl
C18H29ClN2O4 (372.18157440000004)
C78272 - Agent Affecting Nervous System > C29747 - Adrenergic Agent > C72900 - Adrenergic Antagonist D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents > D013566 - Sympathomimetics D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents > D018674 - Adrenergic Antagonists D002317 - Cardiovascular Agents > D000959 - Antihypertensive Agents D002317 - Cardiovascular Agents > D000889 - Anti-Arrhythmia Agents Acebutolol hydrochloride is an orally active β1 adrenergic receptor (β1AR) antagonist. Acebutolol hydrochloride is used in the treatment of hypertension, angina pectoris and cardiac arrhythmias[1][2][3].
6,7-Dihydroxybergamottin
D011838 - Radiation-Sensitizing Agents > D017319 - Photosensitizing Agents > D011564 - Furocoumarins D004791 - Enzyme Inhibitors > D065607 - Cytochrome P-450 Enzyme Inhibitors
Isosinensetin
Isosinensetin is an ether and a member of flavonoids. Isosinensetin is a natural product found in Citrus tankan, Citrus keraji, and other organisms with data available. See also: Tangerine peel (part of); Citrus aurantium fruit rind (part of). Isolated from Citrus subspecies and the round kumquat (Fortunella japonica). Isosinensetin is found in sweet orange, citrus, and fruits. Isosinensetin is found in citrus. Isosinensetin is isolated from Citrus species and the round kumquat (Fortunella japonica). Isosinensetin, a polymethoxylated flavone extracted from pericarpium citri reticulatae viride, exhibits inhibition on P-glycoprotein (P-gp) in MDR1-MDCKII cells[1][2]. Isosinensetin, a polymethoxylated flavone extracted from pericarpium citri reticulatae viride, exhibits inhibition on P-glycoprotein (P-gp) in MDR1-MDCKII cells[1][2].
Tetrahydrocurcumin
Tetrahydrocurcumin (THC), is a product of bacterial or intestinal metabolism of curcumin (via the bacterial enzyme NADPH-dependent curcumin reductase). Curcumin is a yellow, polyphenolic pigment, derived from the rhizomes of a plant (Curcuma longa Linn). It is the principal curcuminoid of the popular Indian spice turmeric, which is a member of the ginger family and is a natural antioxidant exhibiting a variety of pharmacological activities and therapeutic properties. It has long been used as a traditional medicine and as a preservative and coloring agent in foods. In E. coli curcumin is a substrate for the enzyme NADPH-dependent curcumin reductase which catalyzes the metal-independent reduction of curcumin to dihydrocurcumin (DHC) as an intermediate product, followed by further reduction to tetrahydrocurcumin (THC) as an end product. Tetrahydrocurcumin (THC) exhibits many of the same physiologic and pharmacological activities as curcumin and in some systems may exert greater antioxidant activity than curcumin (PMID: 16061427). Tetrahydrocurcumin is a beta-diketone that is curcumin in which both of the double bonds have been reduced to single bonds. It has a role as a metabolite. It is a beta-diketone, a polyphenol and a diarylheptanoid. It is functionally related to a curcumin. Tetrahydrocurcumin is a metabolite found in or produced by Escherichia coli (strain K12, MG1655). Tetrahydrocurcumin is a natural product found in Curcuma longa with data available. Tetrahydrocurcumin (THC), one of the major metabolites of curcumin, exhibits many of the same physiologic and pharmacological activities as curcumin and in some systems may exert greater antioxidant activity than curcumin (PMID: 16061427). Tetrahydrocurcumin is found in turmeric. A beta-diketone that is curcumin in which both of the double bonds have been reduced to single bonds. Tetrahydrocurcumin is a Curcuminoid found in turmeric (Curcuma longa) that is produced by the reduction of Curcumin. Tetrahydrocurcumin inhibit CYP2C9 and CYP3A4. Tetrahydrocurcumin is a Curcuminoid found in turmeric (Curcuma longa) that is produced by the reduction of Curcumin. Tetrahydrocurcumin inhibit CYP2C9 and CYP3A4.
Hydroxymyricanone
Hydroxymyricanone is found in herbs and spices. Hydroxymyricanone is a constituent of Myrica gale (bog myrtle). Constituent of Myrica gale (bog myrtle). Hydroxymyricanone is found in herbs and spices. Hydroxymyricanone is a member of biphenyls.
Tricetin Pentamethyl Ether
3,4,5,5,7-Pentamethoxyflavone is a natural product found in Ficus maxima, Ficus formosana, and other organisms with data available. 3',4',5',5,7-Pentamethoxyflavone, a natural flavonoid extracted from Rutaceae plants, sensitizes chemoresistant cancer cells to chemotherapeutic agents by inhibition of Nrf2 pathway[1]. 3',4',5',5,7-Pentamethoxyflavone, a natural flavonoid extracted from Rutaceae plants, sensitizes chemoresistant cancer cells to chemotherapeutic agents by inhibition of Nrf2 pathway[1].
Deacetyldiltiazem
Deacetyldiltiazem is a metabolite product of the drug Diltiazem (a coronary vasodilator), and is present in the plasma of individuals taking that medication. (PMID 2328299). The action mechanisms involved in the effect of Deacetyldiltiazem on blood rheological (erythrocyte deformation) properties appeared to be similar to Diltiazem, but different from other metabolites of this drug. (PMID 3411434). Deacetyldiltiazem is a metabolite product of the drug Diltiazem (a coronary vasodilator), and is present in the plasma of individuals taking that medication. (PMID 2328299)
Auranetin
Auranetin is found in citrus. Auranetin is isolated from orange peel (Citrus aurantium Isolated from orange peel (Citrus aurantium). Auranetin is found in citrus.
6',7'-Dihydroxybergamottin
Isolated from Citrus macroptera whole fruits, a non-commercial species of the South Pacific. 4-[(6,7-Dihydroxy-3,7-dimethyl-2-octenyl)oxy]-7H-furo[3,2-g][1]benzopyran-7-one is found in citrus. 6,7-Dihydroxybergamottin is found in citrus. 6,7-Dihydroxybergamottin is isolated from Citrus macroptera whole fruits, a non-commercial sp. of the South Pacific. D011838 - Radiation-Sensitizing Agents > D017319 - Photosensitizing Agents > D011564 - Furocoumarins D004791 - Enzyme Inhibitors > D065607 - Cytochrome P-450 Enzyme Inhibitors
Oxidihydroartocarpesin
Oxidihydroartocarpesin is found in fruits. Oxidihydroartocarpesin is isolated from Artocarpus heterophyllus (jackfruit). Isolated from Artocarpus heterophyllus (jackfruit). Oxidihydroartocarpesin is found in jackfruit and fruits.
Citrusin E
Citrusin E is found in citrus. Citrusin E is isolated from oil of lemon peel (Citrus limon). Isolated from oil of lemon peel (Citrus limon). Citrusin E is found in citrus.
Cyclokievitone hydrate
Cyclokievitone hydrate is found in gram bean. Cyclokievitone hydrate is isolated from Phaseolus mungo (black gram).
Homoeriodictyol 4'-isobutyrate
Homoeriodictyol 4-isobutyrate is found in beverages. Homoeriodictyol 4-isobutyrate is isolated from Eriodictyon californicum (yerba santa). Isolated from Eriodictyon californicum (yerba santa). Homoeriodictyol 4-isobutyrate is found in beverages.
(8R,8'R,9S)-9-Hydroxy-3,4-dimethoxy-3',4'-methylenoxy-9,9'-epoxylignan
(8R,8R,9S)-9-Hydroxy-3,4-dimethoxy-3,4-methylenoxy-9,9-epoxylignan is a constituent of Piper chaba (Javanese long pepper) Constituent of Piper chaba (Javanese long pepper)
Licoriphenone
Constituent of licorice (Glycyrrhiza species). Licoriphenone is found in alcoholic beverages and herbs and spices. Licoriphenone is found in alcoholic beverages. Licoriphenone is a constituent of licorice (Glycyrrhiza sp.)
9-Hydroxy-3',4'-dimethoxy-3,4-methylenedioxy-9,9'-epoxylignan
9-Hydroxy-3,4-dimethoxy-3,4-methylenedioxy-9,9-epoxylignan is found in herbs and spices. 9-Hydroxy-3,4-dimethoxy-3,4-methylenedioxy-9,9-epoxylignan is a constituent of Piper nigrum (pepper). Constituent of Piper nigrum (pepper). 9-Hydroxy-3,4-dimethoxy-3,4-methylenedioxy-9,9-epoxylignan is found in herbs and spices.
3',4',5',7,8-Pentamethoxyflavone
3,4,5,7,8-Pentamethoxyflavone is found in fruits. 3,4,5,7,8-Pentamethoxyflavone is a constituent of the roots of Muntingia calabura (Jamaica cherry). Constituent of the roots of Muntingia calabura (Jamaica cherry). 3,4,5,7,8-Pentamethoxyflavone is found in fruits.
2-(4-Allyl-2,6-dimethoxyphenoxy)-1-(3,4-methylenedioxyphenyl)-1-propanol
2-(4-Allyl-2,6-dimethoxyphenoxy)-1-(3,4-methylenedioxyphenyl)-1-propanol is found in herbs and spices. 2-(4-Allyl-2,6-dimethoxyphenoxy)-1-(3,4-methylenedioxyphenyl)-1-propanol is a constituent of Myristica fragrans (nutmeg)
3,4',5,6,8-Pentamethoxyflavone
3,4,5,6,8-Pentamethoxyflavone is found in citrus. 3,4,5,6,8-Pentamethoxyflavone is a constituent of Citrus reticulata (mandarin) leaves. Constituent of Citrus reticulata (mandarin) leaves. 3,4,5,6,8-Pentamethoxyflavone is found in citrus.
(2R,3S,4S,5R,6S)-2-(Hydroxymethyl)-6-[4-(3-hydroxyprop-1-enyl)-2,6-dimethoxyphenoxy]oxane-3,4,5-triol
3',4',5',5,7-Pentamethoxyflavone
3',4',5',5,7-Pentamethoxyflavone, a natural flavonoid extracted from Rutaceae plants, sensitizes chemoresistant cancer cells to chemotherapeutic agents by inhibition of Nrf2 pathway[1]. 3',4',5',5,7-Pentamethoxyflavone, a natural flavonoid extracted from Rutaceae plants, sensitizes chemoresistant cancer cells to chemotherapeutic agents by inhibition of Nrf2 pathway[1].
Tetrahydro-2-(bis(2-chloroethyl)amino)-3-heptyl-6-methyl-2H-1,3,2-oxazaphosphorine 2-oxide
Diamfenetide
D000890 - Anti-Infective Agents > D000977 - Antiparasitic Agents > D000871 - Anthelmintics C254 - Anti-Infective Agent > C276 - Antiparasitic Agent > C250 - Antihelminthic Agent
Medroxalol
C78272 - Agent Affecting Nervous System > C29747 - Adrenergic Agent > C72900 - Adrenergic Antagonist D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents > D018674 - Adrenergic Antagonists D002317 - Cardiovascular Agents > D000959 - Antihypertensive Agents
Pyroglutamyl-phenylalanyl-prolinamide
Quercetin pentamethyl ether
3,5,7,3′,4′-Pentamethoxyflavone is a polymethoxyflavonoid that can be extracted from Kaempferia parviflora. 3,5,7,3′,4′-Pentamethoxyflavone can induce adipogenesis on 3T3-L1 preadipocytes by regulating transcription factors at an early stage of differentiation[1]. 3,5,7,3′,4′-Pentamethoxyflavone is a polymethoxyflavonoid that can be extracted from Kaempferia parviflora. 3,5,7,3′,4′-Pentamethoxyflavone can induce adipogenesis on 3T3-L1 preadipocytes by regulating transcription factors at an early stage of differentiation[1].
2-(3,4-Dihydroxyphenyl)-3,5,7-trimethoxy-6,8-dimethylchromen-4-one
3-Pyridazinamine, N-(1-((3,4-difluorophenyl)methyl)-4-piperidinyl)-6-(trifluoromethyl)-
D018377 - Neurotransmitter Agents > D015259 - Dopamine Agents > D018492 - Dopamine Antagonists
7-Oxomatairesinol
7-oxomatairesinol is a member of the class of compounds known as dibenzylbutyrolactone lignans. Dibenzylbutyrolactone lignans are lignan compounds containing a 3,4-dibenzyloxolan-2-one moiety. 7-oxomatairesinol is practically insoluble (in water) and a very weakly acidic compound (based on its pKa). 7-oxomatairesinol can be found in sesame, which makes 7-oxomatairesinol a potential biomarker for the consumption of this food product.
5-Demethoxynobiletin
5-demethoxynobiletin, also known as 34678-pentamethoxyflavone, is a member of the class of compounds known as 8-o-methylated flavonoids. 8-o-methylated flavonoids are flavonoids with methoxy groups attached to the C8 atom of the flavonoid backbone. 5-demethoxynobiletin is practically insoluble (in water) and an extremely weak acidic compound (based on its pKa). 5-demethoxynobiletin can be found in winter savory, which makes 5-demethoxynobiletin a potential biomarker for the consumption of this food product.
Sylvatesmin
Sylvatesmin is a natural product found in Forsythia suspensa, Lindera praecox, and other organisms with data available. Phillygenin (Phillygenol) is an active ingredient from Forsythia with many medicinal properties, such as antioxidant, reducing blood lipid, inhibition of low density lipoprotein oxidation. Phillygenin (Phillygenol) is an active ingredient from Forsythia with many medicinal properties, such as antioxidant, reducing blood lipid, inhibition of low density lipoprotein oxidation.
Tangeritin
Tangeretin is a pentamethoxyflavone flavone with methoxy groups at positions 4, 5, 6 , 7 and 8. It has a role as an antineoplastic agent and a plant metabolite. Tangeretin is a natural product found in Citrus tankan, Citrus keraji, and other organisms with data available. See also: Tangerine peel (part of); Citrus aurantium fruit rind (part of). Isolated from tangerine peel and Fortunella japonica (round kumquat). Potential nutriceutical. Tangeritin is found in many foods, some of which are apple, broccoli, sweet bay, and tea. Tangeritin is found in apple. Tangeritin is isolated from tangerine peel and Fortunella japonica (round kumquat). Potential nutriceutica A pentamethoxyflavone flavone with methoxy groups at positions 4, 5, 6 , 7 and 8. Tangeretin (Tangeritin), a flavonoid from citrus fruit peels, has been proven to play an important role in anti-inflammatory responses and neuroprotective effects in several disease models, and is a Notch-1 inhibitor. Tangeretin (Tangeritin), a flavonoid from citrus fruit peels, has been proven to play an important role in anti-inflammatory responses and neuroprotective effects in several disease models, and is a Notch-1 inhibitor.
Phillygenin
Phillygenin (Phillygenol) is an active ingredient from Forsythia with many medicinal properties, such as antioxidant, reducing blood lipid, inhibition of low density lipoprotein oxidation. Phillygenin (Phillygenol) is an active ingredient from Forsythia with many medicinal properties, such as antioxidant, reducing blood lipid, inhibition of low density lipoprotein oxidation.
[3aS-(3aalpha,4alpha,5alpha,9aalpha,9bbeta)]-5-(Acetyloxy)-2,3,3a,4,5,9,9a,9b-octahydro-6-methyl-3,9-bis(methylene)-2-oxoazuleno[4,5-b]furan-4-yl ester 2-methylpropanoic acid
3a-Allyl-2-(1,3-benzodioxol-5-yl)-5,7-dimethoxy-3-methyl-3,3a,4,5-tetrahydro-1-benzofuran-6(2H)-one #
5,7-Dihydroxy-3-(4-hydroxyphenyl)-6-(2,3-dihydroxy-3-methylbutyl)-4H-1-benzopyran-4-one
5,7,3,4-Tetrahydroxy-5-(2-epoxy-3-methylbutyl)isoflavanone
Multifidol glucoside
A monosaccharide derivative that consists of multifidol attached to a beta-D-glucopyranosyl residue at position 1 via a glycosidic linkage. Isolated from Acacia mearnsii, it exhibits anti-inflammatory activity.
2-(3,4-Dimethoxyphenyl)-5-hydroxy-3,7-dimethoxy-6-methyl-4H-1-benzopyran-4-one
3,4-Methylenedioxy-2,4,6,beta-tetramethoxychalcone
3,5,7,4-Tetrahydroxy-6-(3-hydroxy-3-methylbutyl)flavone
5,4-Dihydroxy-3,7,3-trimethoxy-6,8-dimethylflavone
Noricaritin
Noricaritin is a natural product found in Phellodendron amurense with data available. Noricaritin is a flavonoid sourced from roots of Epimedium brevicornu Maxim. Noricaritin is a flavonoid sourced from roots of Epimedium brevicornu Maxim.
Isosinensetin
Isosinensetin, a polymethoxylated flavone extracted from pericarpium citri reticulatae viride, exhibits inhibition on P-glycoprotein (P-gp) in MDR1-MDCKII cells[1][2]. Isosinensetin, a polymethoxylated flavone extracted from pericarpium citri reticulatae viride, exhibits inhibition on P-glycoprotein (P-gp) in MDR1-MDCKII cells[1][2].
Kievitol
5,7,3,4,5-pentamethoxyflavone
3',4',5',5,7-Pentamethoxyflavone, a natural flavonoid extracted from Rutaceae plants, sensitizes chemoresistant cancer cells to chemotherapeutic agents by inhibition of Nrf2 pathway[1]. 3',4',5',5,7-Pentamethoxyflavone, a natural flavonoid extracted from Rutaceae plants, sensitizes chemoresistant cancer cells to chemotherapeutic agents by inhibition of Nrf2 pathway[1].
Sinensetin
Sinensetin is a methylated flavonoid found in fruits that has strong anti-vascular and anti-inflammatory properties. Sinensetin is a methylated flavonoid found in fruits that has strong anti-vascular and anti-inflammatory properties.
Tangeretin
Tangeretin (Tangeritin), a flavonoid from citrus fruit peels, has been proven to play an important role in anti-inflammatory responses and neuroprotective effects in several disease models, and is a Notch-1 inhibitor. Tangeretin (Tangeritin), a flavonoid from citrus fruit peels, has been proven to play an important role in anti-inflammatory responses and neuroprotective effects in several disease models, and is a Notch-1 inhibitor.
MEDROXALOL
C78272 - Agent Affecting Nervous System > C29747 - Adrenergic Agent > C72900 - Adrenergic Antagonist D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents > D018674 - Adrenergic Antagonists D002317 - Cardiovascular Agents > D000959 - Antihypertensive Agents
Quercetin pentamethyl ether
3,5,7,3′,4′-Pentamethoxyflavone is a polymethoxyflavonoid that can be extracted from Kaempferia parviflora. 3,5,7,3′,4′-Pentamethoxyflavone can induce adipogenesis on 3T3-L1 preadipocytes by regulating transcription factors at an early stage of differentiation[1]. 3,5,7,3′,4′-Pentamethoxyflavone is a polymethoxyflavonoid that can be extracted from Kaempferia parviflora. 3,5,7,3′,4′-Pentamethoxyflavone can induce adipogenesis on 3T3-L1 preadipocytes by regulating transcription factors at an early stage of differentiation[1].
PENICILLIDE
3,4,5,5,7-Pentamethoxyflavone
3',4',5',5,7-Pentamethoxyflavone, a natural flavonoid extracted from Rutaceae plants, sensitizes chemoresistant cancer cells to chemotherapeutic agents by inhibition of Nrf2 pathway[1]. 3',4',5',5,7-Pentamethoxyflavone, a natural flavonoid extracted from Rutaceae plants, sensitizes chemoresistant cancer cells to chemotherapeutic agents by inhibition of Nrf2 pathway[1].
3,6-Bis(3-methoxy-4-hydroxyphenyl)tetrahydro-1H,3H-furo[3,4-c]furan-1-one
2,4-Di-Me ether,1-O-beta-D-glucopyranoside-6-(1-Methylpropyl)-1,2,4-benzenetriol
(7S,8R,8R)-3,4-dimethoxy-3,4-methylenedioxy-7,9-epoxylignan-9-ol
(E)-3-[(2S,3R)-2,3-dihydro-3-hydroxymethyl-7-methoxy-2-(3,4-dimethoxyphenyl)-1-benzo[b]furan-5-yl]-2-propen-1-ol|hierochin B
methyl rel-(1R,4R,4aR,7R,8S,8aS)-8-[(E)-2-(3-furyl)vinyl]-1,4,4a,5,6,7,8,8a-octahydro-4-hydroxy-4a,8-dimethyl-9-oxo-1,4-(epoxymethano)naphthalene-7-carboxylate|tinosagittone A
O-D-glycero-beta-L-manno-heptopyranosyl-(1<*>2)-D-mannose|O-D-glycero-beta-L-manno-heptopyranosyl-(1[*]2)-D-mannose
2,6-dimethyl-3-hydroxymethyl-5-oxo-1,6-heptadiene-9-O-(6-acetyl-beta-D-glucopyranoside)
1-[(pentanoyl)phloroglucinyl]-beta-D-glucopyranoside|1-[(Pentanoyl)phloroglucinyl]-??-D-glucopyranoside
(12Z,15S,18S)-15-hydroxy-18-bromo-12,16,17-octadecatrienoic acid
(2E)-1-[2,4-dihydroxy-3-(3-hydroxy-3-methylbutyl)-6-methoxyphenyl]-3-(4-hydroxyphenyl)-2-propen-1-one|3-(3-methyl-3-hydroxybutyl)-2,4,4-trihydroxy-6-methoxychalcone|xanthohumol H
2-hydroxy-6-methoxyl-methylene-3-methyl-acetophenone-!-O-beta-D-glucopyranoside
(-)-4-propionyl-2,6-dimethoxyphenyl beta-D-glucopyranoside|1-[4-(beta-D-glucopyranosyloxy)-3,5-dimethoxyphenyl]-1-propanone|4-(beta-D-glucopyranosyloxy)-3,5-dimethoxyphenyl-propanone
4-hydroxy-2-(3-hydroxy-3-methylbutyl)-5-methylphenyl beta-D-glucopyranoside|4-Hydroxy-2-[3-hydroxy-3-methylbutyl]-5-methylphenyl ??-D-glucopyranoside
Me glycoside, benzyl ester-3-Deoxy-D-glycero-D-galacto-2-nonulosonic acid, 9CI
2,5-Dimethoxy-2-(2-propenyl)-4-[2-hydroxy-1-methyl-2-(1,3-benzodioxol-5-yl)ethyl]-3,5-cyclohexadien-1-one
methyl 2-O-beta-D-glucosyloxy-4-methoxybenzenepropanoate|Methyl 2-O-??-D-glucosyloxy-4-methoxybenzenepropanoate|methyl 3-(2-O-beta-D-glucopyranosyl-4-methoxyphenyl)propanoate
(3S)-3-hydroxysedanolide beta-D-glucopyranoside|celephthalide C
(7R,8R,3R)-7-hydroxy-3,4-dimethoxy-3,4-methylenedioxy-6-oxo-Delta-1,4,8-8.3-lignan|2-Allyl-4-[2-hydroxy-1-methyl-2-(3,4-metylenedioxyphenyl)ethyl]4,5-dimethoxy-2,5-cyclohexadien-1-one
5,5,6-Trimethyl-6-(1,2,3-triacetoxy-butyl)-tetrahydro-pyran-2-on|5,5,6-trimethyl-6-(1,2,3-triacetoxy-butyl)-tetrahydro-pyran-2-one
2-methylbut-(2Z)-enoic acid (3R)-5-methoxy-3,4-dihydro-2,2,8-trimethyl-6-oxo-2H,6H-benzo[1,2-b:5,4-b]dipyran-3-yl ester
grevilloside E methyl ester|methyl 5-(1,3-dihydroxyphenyl)butanoate 1-O-beta-D-glucopyranoside
5-(6-hydroxyhexyl)benzene-1,3-diol 1-O-beta-D-glucopyranoside|5-(6-hydroxyhexyl)resorcinol 1-O-beta-D-glucopyranoside|grevilloside H
(E)-6-(2-hydroxy-6-(hydroxymethyl)-4-methylphenoxy)-2-methoxy-3-(3-methylbut-1-en-1-yl)benzoic acid|penikellide A
15-dehydro-17-hydroxycyrtophyllone A|[12,16-epoxy-6-methoxy-11,14,17-trihydroxy-17(15?16)-abeo-5,8,11,13,15-abietapentaen-7-one]
(+)-3-O-demethyleusiderin C.|(7S,8R)-Delta8-3-hydroxy-4,5,5-trimethoxy-7.O.3,8.O.4-neolignan
(10R,16S)-12,16-epoxy-11,14-dihydroxy-6-methoxy-17(15?16)-abeo-abieta-5,8,11,13-tetraene-3,7-dione
(+)-4-O-demethyleusiderin C|(7S,8R)-Delta8-4-hydroxy-3,5,5-trimethoxy-7.O.3,8.O.4-neolignan
4-(4-(3,5-dimethoxyphenyl)hexahydrofuro[3,4-c]furan-1-yl)-2-methoxyphenol|bombasinol A
3,5-dimethyl-6-hydroxy-2-methoxy-4-O-D-glucopyranosyl-oxy-acetophenone
(7R,8R,3S,4R,5R)-Delta8-4-hydroxy-5,5-dimethoxy-3,4-methylenedioxy-2,3,4,5-tetrahydro-2-oxo-7.3,8.5-neolignan|cinerin B
Delta8-3,4,5-trimethoxy-3,6-dihydro-3,4-methylenedioxy-6-oxo-8,3-neolignan
(13E,15R,18R)-15-hydroxy-18-bromo-13,16,17-octadecatrienoic acid
1-Aldehyde,8-O-(2-acetyl-beta-D-glucopyranoside)-(E)-2-Methyl-6-methylene-2-octene-1,8-diol|7-Formyl-3-methylene-6E-octenol-O-beta-D-(2-O-acetylglucopyranoside)|7-Formyl-3-methylene-6E-octenol-O-beta-D-<2-O-acetylglucopyranoside>
6,7-Dihydroxy-8-geranylpsoralen|9-[(6,7-dihydroxy-3,7-dimethyl-2-octenyl)oxy]-7H-furo[3,2-g][1]benzopyran-7-one
1-[(3-methylbutanoyl)phloroglucinyl]-beta-D-glucopyranoside|1-[(3-methylbutyryl)phloroglucinyl]-beta-D-glucopyranoside|2-(3-methylbutyryl)phloroglucinol-1-O-beta-D-glucopyranoside|2-(3-methylbutyryl)phloroglucinol-beta-D-glucopyranoside|2-beta-D-glucopyranosyloxy-4,6-dihydroxyisovalerophenone|lysidiside A
(1S, 3S, 5R, 6R, 7R, 8S)-3-acetoxy-8-methacrylyloxyguai-4(15), 10(14), 11(13)-trien-6,12-olide
3-hydroxyl-2-methyl-4H-pyran-4-one-3-O-(6-isovaleryl)-beta-D-glucopyranoside
8beta-((2-R*,3R*)-2-Methyl-2,3-epoxybutyryloxy)dehydroleucodin|8beta-<(2-R*,3R*)-2-Methyl-2,3-epoxybutyryloxy>dehydroleucodin
TSC cpd
Trans Sodium Crocetinate is the sodium salt of the trans-isomer of the carotenoid crocetin with potential antihypoxic and radiosensitizing activities. Trans sodium crocetinate (TSC) increases the diffusion rate of oxygen in aqueous solutions such as from plasma to body tissue. The agent has been shown to increase available oxygen during hypoxic and ischemic conditions that may occur in hemorrhage, vascular and neurological disorders, and in the tumor microenvionment. Crocetin (Transcrocetin) disodium, extracted from saffron (Crocus sativus L.), acts as an NMDA receptor antagonist with high affinity. Crocetin (Transcrocetin) disodium, extracted from saffron (Crocus sativus L.), acts as an NMDA receptor antagonist with high affinity. Crocetin (Transcrocetin) disodium, extracted from saffron (Crocus sativus L.), acts as an NMDA receptor antagonist with high affinity.
DGR7D6J5TR
syringin
Syringin, also known as eleutheroside b or beta-terpineol, is a member of the class of compounds known as phenolic glycosides. Phenolic glycosides are organic compounds containing a phenolic structure attached to a glycosyl moiety. Some examples of phenolic structures include lignans, and flavonoids. Among the sugar units found in natural glycosides are D-glucose, L-Fructose, and L rhamnose. Syringin is slightly soluble (in water) and a very weakly acidic compound (based on its pKa). Syringin can be found in caraway, fennel, and lemon, which makes syringin a potential biomarker for the consumption of these food products. Syringin is a natural chemical compound first isolated from the bark of lilac (Syringa vulgaris) by Meillet in 1841. It has since been found to be distributed widely throughout many types of plants. It is also called eleutheroside B, and is found in Eleutherococcus senticosus (Siberian ginseng). It is also found in dandelion coffee . Syringin is a main bioactive phenolic glycoside in Acanthopanax senticosus, with anti-osteoporosis activity. Syringin prevents cardiac hypertrophy induced by pressure overload through the attenuation of autophagy[1][2]. Syringin is a main bioactive phenolic glycoside in Acanthopanax senticosus, with anti-osteoporosis activity. Syringin prevents cardiac hypertrophy induced by pressure overload through the attenuation of autophagy[1][2].
4-[(3S,3aR,6S,6aR)-6-(3,4-dimethoxyphenyl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan-3-yl]-2-methoxyphenol
(2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-[4-[(E)-3-hydroxyprop-1-enyl]-2,6-dimethoxyphenoxy]oxane-3,4,5-triol
Arctigenin
Annotation level-1 Arctigenin ((-)-Arctigenin), a biologically active lignan, can be used as an antitumor agent. Arctigenin exhibits potent antioxidant, anti-inflammatory and antiviral (influenza A virus) activities. Arctigenin can be used for the research of metabolic disorders, and central nervous system dysfunctions[1][2][3]. Arctigenin ((-)-Arctigenin), a biologically active lignan, can be used as an antitumor agent. Arctigenin exhibits potent antioxidant, anti-inflammatory and antiviral (influenza A virus) activities. Arctigenin can be used for the research of metabolic disorders, and central nervous system dysfunctions[1][2][3].
C20H24N2O5_3-Pyridinecarboxylic acid, 1,4-dihydro-6-(hydroxyphenylmethyl)-1-[2-[(3-methyl-1-oxobutyl)amino]ethyl]-4-oxo
C21H24O6_5H,7H-Dibenzo[b,g][1,5]dioxocin-5-one, 11-hydroxy-3-(1-hydroxy-3-methylbutyl)-4-methoxy-9-methyl
C22H20N4O2_3,6-Bis(1H-indol-3-ylmethyl)-2,5-piperazinedione
Biocytin
C16H28N4O4S (372.18311680000005)
A monocarboxylic acid amide that results from the formal condensation of the carboxylic acid group of biotin with the N(6)-amino group of L-lysine.
6-hydroxy-2-(1-hydroxy-3-methylbutyl)-1-methoxy-8-methyl-10H-benzo[b][1,5]benzodioxocin-12-one
Fellutanine A
Origin: Microbe; SubCategory_DNP: Peptides, Cyclic peptides, Piperazines
(2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-[4-[(E)-3-hydroxyprop-1-enyl]-2,6-dimethoxyphenoxy]oxane-3,4,5-triol [IIN-based: Match]
6-hydroxy-2-(1-hydroxy-3-methylbutyl)-1-methoxy-8-methyl-10H-benzo[b][1,5]benzodioxocin-12-one_major
Ala Ala Asp Pro
Ala Ala Pro Asp
Ala Asp Ala Pro
Ala Asp Pro Ala
Ala Glu Gly Pro
Ala Glu Pro Gly
Ala Gly Glu Pro
Ala Gly Pro Glu
Ala Pro Ala Asp
Ala Pro Asp Ala
Ala Pro Glu Gly
Ala Pro Gly Glu
Cys Gly Gly His
C13H20N6O5S (372.12158300000004)
Cys Gly His Gly
C13H20N6O5S (372.12158300000004)
Cys Gly Pro Pro
Cys His Gly Gly
C13H20N6O5S (372.12158300000004)
Cys Pro Gly Pro
Cys Pro Pro Gly
Asp Ala Ala Pro
Asp Ala Pro Ala
Asp Pro Ala Ala
Glu Ala Gly Pro
Glu Ala Pro Gly
Glu Gly Ala Pro
Glu Gly Pro Ala
Glu Pro Ala Gly
Glu Pro Gly Ala
Gly Ala Glu Pro
Gly Ala Pro Glu
Gly Cys Gly His
C13H20N6O5S (372.12158300000004)
Gly Cys His Gly
C13H20N6O5S (372.12158300000004)
Gly Cys Pro Pro
Gly Glu Ala Pro
Gly Glu Pro Ala
Gly Gly Cys His
C13H20N6O5S (372.12158300000004)
Gly Gly His Cys
C13H20N6O5S (372.12158300000004)
Gly His Cys Gly
C13H20N6O5S (372.12158300000004)
Gly His Gly Cys
C13H20N6O5S (372.12158300000004)
Gly Pro Ala Glu
Gly Pro Cys Pro
Gly Pro Glu Ala
Gly Pro Pro Cys
His Cys Gly Gly
C13H20N6O5S (372.12158300000004)
His Gly Cys Gly
C13H20N6O5S (372.12158300000004)
His Gly Gly Cys
C13H20N6O5S (372.12158300000004)
Pro Ala Ala Asp
Pro Ala Asp Ala
Pro Ala Glu Gly
Pro Ala Gly Glu
Pro Cys Gly Pro
Pro Cys Pro Gly
Pro Asp Ala Ala
Pro Glu Ala Gly
Pro Glu Gly Ala
Pro Gly Ala Glu
Pro Gly Cys Pro
Pro Gly Glu Ala
Pro Gly Pro Cys
Pro Pro Cys Gly
Pro Pro Gly Cys
6,7-dihydroxy Bergamottin
Tetrahydrocurcumin
Tetrahydrocurcumin is a Curcuminoid found in turmeric (Curcuma longa) that is produced by the reduction of Curcumin. Tetrahydrocurcumin inhibit CYP2C9 and CYP3A4. Tetrahydrocurcumin is a Curcuminoid found in turmeric (Curcuma longa) that is produced by the reduction of Curcumin. Tetrahydrocurcumin inhibit CYP2C9 and CYP3A4.
2-(4-Allyl-2,6-dimethoxyphenoxy)-1-(3,4-methylenedioxyphenyl)-1-propanol
3,4-Dimethoxy-3,4-desmethylenecubebin
3',4'-Dimethoxy-3',4'-desmethylenecubebin
Licoriphenone
Citrusin E
Hydroxymyricanone
15S-hydroxy-18-bromo-12Z,16,17S-octadecatrienoic acid
15R-hydroxy-18-bromo-13E,16,17R-octadecatrienoic acid
15S-hydroxy-18S-bromo-12E,16,17-octadecatrienoic acid
C18H29O3Br (372.12999440000004)
15R-hydroxy-18R-bromo-13Z,16,17-octadecatrienoic acid
C18H29O3Br (372.12999440000004)
1-amino-5-(trityloxymethyl)pyrrolidin-2-one
C24H24N2O2 (372.18376839999996)
[1-{[(2-Methyl-2-propanyl)oxy]carbonyl}-5-(1-piperidinylcarbonyl) -1H-indol-2-yl]boronic acid
(3-N-BOC-AMINO-PYRROLIDIN-1-YL)-THIOPHEN-3-YL-ACETICACID
1-PYRROLIDIN-2-(2-CHLOROPHENYL)-2-(N-CBZ-N-METHYL)AMINO-ETHANE
1-PYRROLIDIN-2-(3-CHLOROPHENYL)-2-(N-CBZ-N-METHYL)AMINO-ETHANE
N-[(1R)-3-(Dimethylamino)-3-oxo-1-[(phenylthio)Methyl]propyl]carbamic Acid Phenylmethyl Ester
benzoic acid,2,2-dimethylpropane-1,3-diol,hexanedioic acid
3H-Indolium,2-[2-[(2,4-dimethoxyphenyl)amino]ethenyl]-1,3,3-trimethyl-, chloride (1:1)
2,2-Spirobi[2H-1-benzopyran]-6,6,7,7-tetrol,3,3,4,4-tetrahydro-4,4,4,4-tetramethyl-
3-[(2-CHLOROPHENYL)(2-HYDROXYETHYLAMINO)METHYL]-1H-INDOLE-2-CARBOXYLIC ACID ETHYL ESTER
2-acetamido-3,4,6-tri-o-acetyl-2-deoxy-beta-d-glucopyranosyl azide
Cyclo(-Trp-Trp)
Cyclo(L-Trp-L-Trp) is an antibiotic, and shows antimicrobial activity. Cyclo(L-Trp-L-Trp) can inhibit A. baumannii, as well as Candida albicans, Bacillus subtilis, Micrococcus luteus, Saccharomyces cerevisiae, Aspergillus niger, Staphylococcus aureus. Cyclo(L-Trp-L-Trp) can be used in microbial infection research[1].
2,2-[[4-[(6-methoxybenzothiazol-2-yl)azo]phenyl]imino]bisethanol
C18H20N4O3S (372.12560500000006)
2-AMINO-6-(MORPHOLINOMETHYL)-4-PHENYL-5H-INDENO[1,2-D]PYRIMIDIN-5-ONE
4-(Chloromethyl)-5-methyl-1-(triphenylmethyl)-1H-imidazole
1-Decyl-3-Methylimidazolium Triflate
C15H27F3N2O3S (372.16943879999997)
3,3-dimethyl-13-phenyl-4,13-dihydro-2H-indazolo[1,2-b]phthalazine-1,6,11-trione
4-(2-Chloroethyl)-1-(triphenylmethyl)-1H-imidazole
3,5-Pyridinedicarboxylicacid, 2,6-dimethyl-4-(3-nitrophenyl)-, 3,5-diethyl ester
4-(4-ETHOXYPHENOXYCARBONYL)PHENYL PENTYL CARBONATE
PF-04217903
C19H16N8O (372.14470059999996)
C274 - Antineoplastic Agent > C2189 - Signal Transduction Inhibitor > C129824 - Antineoplastic Protein Inhibitor C274 - Antineoplastic Agent > C163758 - Targeted Therapy Agent > C164000 - c-Met-targeting Agent C471 - Enzyme Inhibitor > C1404 - Protein Kinase Inhibitor > C1967 - Tyrosine Kinase Inhibitor C471 - Enzyme Inhibitor > C129825 - Antineoplastic Enzyme Inhibitor
(9H-FLUOREN-9-YL)METHYL ((1R,4R)-4-AMINOCYCLOHEXYL)CARBAMATE HYDROCHLORIDE
ly 272015 hydrochloride
LY-272015 hydrochloride is an orally active, specific 5-HT2B receptor antagonist. LY-272015 hydrochloride completely inhibits the phosphorylation of ERK2 induced by 5-HT or BW723C86. LY-272015 hydrochloride is antihypertensive in Deoxycorticosterone Acetate (DOCA)-salt-hypertensive rats[1][2].
N,N-(Methylene-p-phenylene)-bis-[N-(2-hydroxyethyl)]urea
N-[(1R)-1-Hydroperoxy-3-methylbutyl]-Nα-(2-pyrazinylcarbonyl)-L-phenylalaninamide
N-[(1S)-1-Hydroperoxy-3-methylbutyl]-Nα-(2-pyrazinylcarbonyl)-L-phenylalaninamide
(1R,4R)-[4-(6-Chloro-2-Methylsulfanyl-pyriMidin-4-ylaMino)-cyclohexyl]-carbaMic acid tert-butyl ester
(2R,3R)-3-(tert-butyl)-4-(2,6-dimethoxyphenyl)-2-isopropyl-2,3-dihydrobenzo[d][1,3]oxaphosphole
C22H29O3P (372.18542140000005)
4-[[3-[2-(3-Chlorophenyl)ethyl]-2-pyridinyl]carbonyl]-1-piperidinecarboxylic Acid
(2S,3S)-3-(tert-butyl)-4-(2,6-dimethoxyphenyl)-2-isopropyl-2,3-dihydrobenzo[d][1,3]oxaphosphole
C22H29O3P (372.18542140000005)
N-Cbz-L-lysine tert-butyl ester hydrochloride
C18H29ClN2O4 (372.18157440000004)
Dihydroxybergamottin
D011838 - Radiation-Sensitizing Agents > D017319 - Photosensitizing Agents > D011564 - Furocoumarins D004791 - Enzyme Inhibitors > D065607 - Cytochrome P-450 Enzyme Inhibitors
(9H-Fluoren-9-yl)methyl 4-(aminomethyl)piperidine-1-carboxylate hydrochloride
N-Acetyl-leucyl-phenylalanyl trifluoromethyl ketone
Sulfisoxazole diolamine
C254 - Anti-Infective Agent > C29739 - Sulfonamide Anti-Infective Agent D000890 - Anti-Infective Agents > D013424 - Sulfanilamides
1,7-Bis(3-methoxy-4-hydroxyphenyl)-5-hydroxy-4-hepten-3-one
(R)-2-Amino-3-((3-octylphenyl)amino)-3-oxopropyl dihydrogen phosphate
C17H29N2O5P (372.18139940000003)
D007155 - Immunologic Factors > D007166 - Immunosuppressive Agents > D000081243 - Sphingosine 1 Phosphate Receptor Modulators
2-[[1-Oxo-2-[2-oxo-2-(1-piperidinyl)ethyl]-5-isoquinolinyl]oxy]acetic acid ethyl ester
3-[4,8-dimethyl-2-oxo-7-(2H-tetrazol-5-ylmethoxy)-1-benzopyran-3-yl]propanoic acid ethyl ester
2-ethoxy-N-(3-(3-methylimidazo[1,2-a]pyrimidin-2-yl)phenyl)benzamide
4-Pyrimidinecarboxylic acid, 2,6-bis(trimethylsiloxy)-, trimethylsilyl ester
C14H28N2O4Si3 (372.13568080000005)
5-(2-Aminoethyl)-3-{5-[amino(iminio)methyl]-1H-benzimidazol-2-YL}-1,1-biphenyl-2-olate
Arctigenen
Arctigenin ((-)-Arctigenin), a biologically active lignan, can be used as an antitumor agent. Arctigenin exhibits potent antioxidant, anti-inflammatory and antiviral (influenza A virus) activities. Arctigenin can be used for the research of metabolic disorders, and central nervous system dysfunctions[1][2][3]. Arctigenin ((-)-Arctigenin), a biologically active lignan, can be used as an antitumor agent. Arctigenin exhibits potent antioxidant, anti-inflammatory and antiviral (influenza A virus) activities. Arctigenin can be used for the research of metabolic disorders, and central nervous system dysfunctions[1][2][3].
Biocytin zwitterion
C16H28N4O4S (372.18311680000005)
An L-alpha-amino acid zwitterion obtained by transfer of a proton from the carboxy to the amino group of biocytin; major species at pH 7.3.
7-O-acetylsalutaridinol(1+)
C21H26NO5+ (372.18108860000007)
The conjugate acid of 7-O-acetylsalutaridinol arising from protonation of the tertiary amino function.
methyl-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]azanium
C21H26NO5+ (372.18108860000007)
2-(2-methylphenoxy)-N-[2-(4-methylphenyl)-2H-benzotriazol-5-yl]acetamide
N-(4-methoxyphenyl)-2-(3-nitrophenyl)-4-quinazolinamine
C21H16N4O3 (372.12223459999996)
1-[(3-methylbutanoyl)phloroglucinyl]-beta-D-glucopyranoside
A beta-D-glucoside compound having a (3-methylbutanoyl)phloroglucinyl moiety at the anomeric position. Isolated from the whole plant of Indigofera heterantha, it exhibits lipoxygenase inhibitory activity.
4-[[(3,4-Dimethoxyanilino)-oxomethyl]amino]benzoic acid butyl ester
2-[(3-methoxyphenoxy)methyl]-7-phenyl-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidine
C20H16N6O2 (372.13346759999996)
N-[4-[(1,1-dioxo-1,4-thiazinan-4-yl)methyl]phenyl]-3,4-dimethylbenzamide
4-O-beta-D-glucopyranosyl-L-glycero-alpha-D-manno-heptopyranose
4-[[(4-tert-butylphenyl)-oxomethyl]hydrazo]-N-(5-methyl-3-isoxazolyl)-4-oxobutanamide
(-)-3,4-Dimethoxy-3,4-desmethylenedioxycubebin
A lignan that consists of tetrahydrofuran-2-ol substituted by a 1,3-benzodioxol-5-ylmethyl group at positions 3 and a 3,4-dimethoxybenzyl group at position 4 (the 3R,4R stereoisomer). It is isolated from the leaves of Piper nigrum and exhibits histamine release inhibitory activity.
3,4-dihydro-2H-quinolin-1-yl-[4-(phenylmethyl)-5-thieno[3,2-b]pyrrolyl]methanone
N-(2-phenyl-5-benzotriazolyl)-2,3-dihydro-1,4-benzodioxin-6-carboxamide
C21H16N4O3 (372.12223459999996)
1-[(pentanoyl)-phloroglucinyl]-beta-D-glucopyranoside
A beta-D-glucoside compound having a (pentanoyl)-phloroglucinyl moiety at the anomeric position. Isolated from the whole plant of Indigofera heterantha, it exhibits lipoxygenase inhibitory activity.
3-[5-(5-methyl-2-thiophenyl)-1,3,4-oxadiazol-2-yl]-N-[2-(3-pyridinyloxy)propyl]propanamide
C18H20N4O3S (372.12560500000006)
2-(3-Hydroxyphenyl)-6-(1-piperidinyl)benzo[de]isoquinoline-1,3-dione
3-Methyl-7-pentyl-8-(2-phenylethylthio)purine-2,6-dione
6-(2-Chlorophenyl)-3-methyl-2-[4-morpholinyl(oxo)methyl]-1,5,6,7-tetrahydroindol-4-one
N-[2-(3-ethoxypropylamino)-1-(4-methoxyphenyl)-2-oxoethyl]-2-pyrazinecarboxamide
N-(2-methoxyphenyl)-4,6-bis(4-morpholinyl)-1,3,5-triazin-2-amine
C18H24N6O3 (372.19097939999995)
N-[1-(1H-benzimidazol-2-yl)ethyl]-3-(dimethylsulfamoyl)benzamide
C18H20N4O3S (372.12560500000006)
N-[3-[[2-(2-fluorophenyl)-4-quinazolinyl]amino]phenyl]acetamide
C22H17FN4O (372.13863239999995)
2-[2-[4-(4-Fluorophenyl)-1-piperazinyl]-2-oxoethoxy]benzoic acid methyl ester
4-(6-chloro-2-methyl-2,3-dihydro-1,4-benzoxazin-4-yl)-4-oxo-N-(phenylmethyl)butanamide
N-[(E)-[5-(4-Methyl-3-nitrophenyl)furan-2-yl]methylideneamino]-2-morpholin-4-ylacetamide
2-[2-(1-Azabicyclo[2.2.2]octan-3-ylidene)-2-fluoroethoxy]-9H-carbazole;hydrochloride
6-O-D-glycero-alpha-D-manno-heptopyranosyl-beta-D-glucopyranose
1-Butyl-N-(5-ethyl-1,3,4-thiadiazol-2-yl)-4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carboxamide
C18H20N4O3S (372.12560500000006)
17beta-(Acetylthio)estra-1,3,5(10)-trien-3-ol acetate
2-(1-oxopropylamino)-6-(phenylmethyl)-5,7-dihydro-4H-thieno[2,3-c]pyridine-3-carboxylic acid ethyl ester
N-[[(2R,3S,4R)-4-(hydroxymethyl)-3-[4-[(E)-prop-1-enyl]phenyl]azetidin-2-yl]methyl]benzenesulfonamide
(1R,5S)-6-(3-fluorophenyl)sulfonyl-7-[4-[(E)-prop-1-enyl]phenyl]-3,6-diazabicyclo[3.1.1]heptane
(1S,5R)-3-(2-fluorophenyl)sulfonyl-7-[4-[(E)-prop-1-enyl]phenyl]-3,6-diazabicyclo[3.1.1]heptane
6-methoxy-1-(3-methoxyprop-1-ynyl)-2-[(5-nitro-2-furanyl)methyl]-3,4-dihydro-1H-isoquinolin-7-ol
5,7-dihydroxy-3-[4-hydroxy-2-methoxy-3-(3-methylbut-2-en-1-yl)phenyl]-2,3,4a,8a-tetrahydro-4H-chromen-4-one
(1S,5R)-7-[4-[(Z)-prop-1-enyl]phenyl]-6-[[2-(trifluoromethyl)phenyl]methyl]-3,6-diazabicyclo[3.1.1]heptane
3,4,5-Trihydroxy-6-[4-(3-hydroxybutyl)-2-methoxyphenoxy]oxane-2-carboxylic acid
(4Z)-2-Ethyl-4-[(4-ethylphenyl)methylidene]-1,3-dihydrobenzo[b][1,6]naphthyridine-10-carboxylic acid
C24H24N2O2 (372.18376839999996)
4-Hydroxy-1-(4-hydroxy-3-methoxyphenyl)-7-(3-methoxyphenyl)heptane-3,5-dione
(2S)-2-amino-6-[[4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-1-ium-2-yl]amino]hexanoic acid
2-[[(2R)-2-(4-carboxybutanoyloxy)-3-hydroxypropoxy]-hydroxyphosphoryl]oxyethyl-trimethylazanium
2,3-Dihydroxypropyl (2-hydroxy-3-nonoxypropyl) hydrogen phosphate
C15H33O8P (372.19129480000004)
[3-[2,3-Dihydroxypropoxy(hydroxy)phosphoryl]oxy-2-hydroxypropyl] octanoate
Acetic acid, 2-trimethylsiloxy-2,2-diphenyl-, trimethylsilyl ester
C20H28O3Si2 (372.15768979999996)
(3S)-3-(Tert-butyldimethylsilyloxy)-5-tosylpentanol
(3S)-3,6-bis(1H-indol-3-ylmethyl)piperazine-2,5-dione
(8R,8R,9S)-9-Hydroxy-3,4-dimethoxy-3,4-methylenoxy-9,9-epoxylignan
(R)-(+)-6,7-dihydroxybergamottin
A natural product found in Citrus hystrix.
2-(Hydroxymethyl)-6-[4-(3-hydroxyprop-1-enyl)-2,6-dimethoxyphenoxy]oxane-3,4,5-triol
AS-186a
A dibenzodioxocine that is 5H,7H-dibenzo[b,g][1,5]dioxocin-5-one substituted by a hydroxy group at position 11, a (1S)-1-hydroxy-3-methylbutyl group at position 3 and a methoxy and a methyl group at positions 4 and 9 respectively. It is isolated from the culture broth of Penicillium asperosporum and acts as an acyl-CoA:cholesterol acyltransferase inhibitor.
fellutanine
A member of the class of 2,5-diketopiperazines that is piperazine-2,5-dione substituted by 1H-indol-3-ylmethyl groups at positions 3 and 6 respectively. Isolated from Penicillium species, it exhibits antibacterial activity.
CBL0137 (hydrochloride)
CBL0137 hydrochloride is an inhibitor of the histone chaperone, FACT. CBL0137 hydrochloride can also activate p53 and inhibits NF-κB with EC50s of 0.37 and 0.47 μM, respectively.
CC-115 (hydrochloride)
CC-115 hydrochloride is a potent and dual DNA-PK and mTOR kinase inhibitor with IC50s of 13 nM and 21 nM, respectively. CC-115 blocks both mTORC1 and mTORC2 signaling. CC-115 hydrochloride is a potent and dual DNA-PK and mTOR kinase inhibitor with IC50s of 13 nM and 21 nM, respectively. CC-115 blocks both mTORC1 and mTORC2 signaling.
N-[(4-Aminophenyl)methyl]adenosine
N-[(4-Aminophenyl)methyl]adenosine is a adenosine receptor inhibitor, with Ki of 29 nM for Rat ecto-5′-Nucleotidase. IC50 value: 29.0 ± 1.7 nM (Ki) Target: Adenosine Receptor N-[(4-Aminophenyl)methyl]adenosine is a adenosine receptor inhibitor, with Ki of 29 nM for Rat ecto-5′-Nucleotidase. IC50 value: 29.0 ± 1.7 nM (Ki) Target: Adenosine Receptor
YK-3-237
YK-3-237, a SIRT1 activator, targets mutant p53. YK-3-237 inhibits the proliferation of triple-negative breast cancer cells[1].