Exact Mass: 335.1063
Exact Mass Matches: 335.1063
Found 487 metabolites which its exact mass value is equals to given mass value 335.1063,
within given mass tolerance error 0.05 dalton. Try search metabolite list with more accurate mass tolerance error
0.01 dalton.
trifluralin
D050258 - Mitosis Modulators > D050256 - Antimitotic Agents > D050257 - Tubulin Modulators D000970 - Antineoplastic Agents > D050256 - Antimitotic Agents CONFIDENCE standard compound; EAWAG_UCHEM_ID 123 D010575 - Pesticides > D006540 - Herbicides D016573 - Agrochemicals
N-acetylglucosaminylasparagine
Aspartylglycosamine, also known as n4-(beta-N-acetyl-D-glucosaminyl)-L-asparagine or 1-beta-aspartyl-N-acetyl-D-glucosaminylamine, is a member of the class of compounds known as glycosylamines. Glycosylamines are compounds consisting of an amine with a beta-N-glycosidic bond to a carbohydrate, thus forming a cyclic hemiaminal ether bond (alpha-amino ether). Aspartylglycosamine is soluble (in water) and a moderately acidic compound (based on its pKa). Aspartylglycosamine can be found primarily in urine, as well as in human spleen tissue. Within the cell, aspartylglycosamine is primarily located in the cytoplasm. Moreover, aspartylglycosamine is found to be associated with aspartylglucosaminuria, which is an inborn error of metabolism. Large amount of aspartylglycosamine appears in patients with aspartylglycosaminuria corresponding to decreased activity of aspartylglycosamine amido hydrolase. Large amount of aspartylglycosamine appears in patients with aspartylglycosaminuria, which is a metabolic disorder associated with decreased activity of aspartylglycosamine amido hydrolase. [HMDB]
S-Formylglutathione
S-Formylglutathione, also known as L-gamma-glutamyl-S-formyl-L-cysteinylglycine, belongs to the class of organic compounds known as oligopeptides. These are organic compounds containing a sequence of three to ten alpha-amino acids joined by peptide bonds. S-Formylglutathione is a very strong basic compound (based on its pKa). S-Formylglutathione exists in all living species, ranging from bacteria to humans. Outside of the human body, S-formylglutathione has been detected, but not quantified in, several different foods, such as sweet marjorams, muscadine grapes, amaranths, lemon verbena, and garden tomato. This could make S-formylglutathione a potential biomarker for the consumption of these foods. S-Formylglutathione is formed from the oxidation of S-hydroxymethylglutathione by the enzyme formaldehyde dehydrogenase (FDH; EC 1.2.1.1) in the presence of NAD (PMID: 2806555). S-Formylglutathione is formed from the oxidation of S-hydroxymethylglutathione by the enzyme formaldehyde dehydrogenase (FDH; EC 1.2.1.1) in the presence of NAD (PubMed ID 2806555) [HMDB]. S-Formylglutathione is found in many foods, some of which are horseradish tree, wild carrot, japanese walnut, and red beetroot.
Dihydroneopterin phosphate
Dihydroneopterin phosphate is involved in the folate biosynthesis pathway. Dihydroneopterin phosphate is produced from 2-Amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)dihydropteridine. triphosphate by [E3.6.1.-]. Dihydroneopterin phosphate is then converted to Dihydroneopterin by [E3.6.1.-]. Dihydroneopterin phosphate is involved in the folate biosynthesis pathway. Dihydroneopterin phosphate is produced from 2-Amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)dihydropteridine
Mitomycin B
7-demethylmitomycin A
A member of the family of mitomycins that is mitomycin A in which the methoxy group on the quinone ring is replaced by a hydroxy group.
sulfanitran
C254 - Anti-Infective Agent > C29739 - Sulfonamide Anti-Infective Agent D000890 - Anti-Infective Agents > D013424 - Sulfanilamides
Oxonantenine
Alkaloid from Laurelia sempervirens (Peruvian nutmeg). Oxonantenine is found in custard apple, cherimoya, and herbs and spices. Oxonantenine is found in cherimoya. Oxonantenine is an alkaloid from Laurelia sempervirens (Peruvian nutmeg).
gamma-Glutamyl-S-methylcysteinyl-beta-alanine
gamma-Glutamyl-S-methylcysteinyl-beta-alanine is found in pulses. gamma-Glutamyl-S-methylcysteinyl-beta-alanine is a constituent of the seeds of the mung bean (Vigna radiata). Constituent of the seeds of the mung bean (Vigna radiata). gamma-Glutamyl-S-methylcysteinyl-beta-alanine is found in pulses.
Tryptophyl-Methionine
Tryptophyl-Methionine is a dipeptide composed of tryptophan and methionine. It is an incomplete breakdown product of protein digestion or protein catabolism. Some dipeptides are known to have physiological or cell-signaling effects although most are simply short-lived intermediates on their way to specific amino acid degradation pathways following further proteolysis. This dipeptide has not yet been identified in human tissues or biofluids and so it is classified as an Expected metabolite.
Methionyl-Tryptophan
Methionyl-Tryptophan is a dipeptide composed of methionine and tryptophan. It is an incomplete breakdown product of protein digestion or protein catabolism. Some dipeptides are known to have physiological or cell-signaling effects although most are simply short-lived intermediates on their way to specific amino acid degradation pathways following further proteolysis. This dipeptide has not yet been identified in human tissues or biofluids and so it is classified as an Expected metabolite.
S-formylglutathionate(1-)
S-formylglutathionate(1-) is considered to be slightly soluble (in water) and acidic
8-Oxycoptisine
2-Amino-5-[[1-(carboxymethylamino)-3-ethylsulfanyl-1-oxopropan-2-yl]amino]-5-oxopentanoic acid
3-(Phosphonomethyl)-5-phenyl-D-phenylalanine
Diethylenetriaminetetraacetic acid
N-(N-L-gamma-Glutamyl-L-cysteinyl)glycine monoethyl ester
isoxicam
C78272 - Agent Affecting Nervous System > C241 - Analgesic Agent > C2198 - Nonnarcotic Analgesic D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents D002491 - Central Nervous System Agents > D000700 - Analgesics D000893 - Anti-Inflammatory Agents D018501 - Antirheumatic Agents
1-(4,5-Dimethylthiazol-2-yl)-3,5-diphenylformazan
Pirifibrate
Ramixotidine
C78276 - Agent Affecting Digestive System or Metabolism > C29701 - Anti-ulcer Agent > C29702 - Histamine-2 Receptor Antagonist
2-Methyl-N-(5-methyl-3-isoxazolyl)-1,1,4-trioxo-3H-1$l^{6},2-benzothiazine-3-carboxamide
3-[(2-Aminoethylamino)methyl]-3-[bis(carboxymethyl)amino]pentanedioic acid
3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyl-2,3-dihydro-1H-tetrazole
(Z)-3-Amino-3-(4-aminophenylthio)-2-(2-(trifluoromethyl)phenyl)acrylonitrile
2-Methyl-furan-3-carbothioic acid [4-chloro-3-(3-methyl-but-2-enyloxy)-phenyl]-amide
Progabide acid
D002491 - Central Nervous System Agents > D000927 - Anticonvulsants
caffeoylshikimate
Caffeoylshikimate is also known as caffeoylshikimic acid. Caffeoylshikimate is slightly soluble (in water) and a weakly acidic compound (based on its pKa). Caffeoylshikimate can be found in a number of food items such as swamp cabbage, green zucchini, hazelnut, and wax gourd, which makes caffeoylshikimate a potential biomarker for the consumption of these food products.
Dicentrinone
D000970 - Antineoplastic Agents > D059003 - Topoisomerase Inhibitors > D059004 - Topoisomerase I Inhibitors D004791 - Enzyme Inhibitors
8-Oxycoptisine
8-Oxocoptisine is a natural product found in Thalictrum delavayi, Fumaria indica, and other organisms with data available. 8-Oxocoptisine is a natural protoberberine alkaloid with anti-cancer activity[1]. 8-Oxocoptisine is a natural protoberberine alkaloid with anti-cancer activity[1].
Cloquintocet-mexyl
CONFIDENCE standard compound; INTERNAL_ID 286; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 10219; ORIGINAL_PRECURSOR_SCAN_NO 10218 CONFIDENCE standard compound; INTERNAL_ID 286; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 10248; ORIGINAL_PRECURSOR_SCAN_NO 10246 CONFIDENCE standard compound; INTERNAL_ID 286; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 10275; ORIGINAL_PRECURSOR_SCAN_NO 10273 CONFIDENCE standard compound; INTERNAL_ID 286; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 10288; ORIGINAL_PRECURSOR_SCAN_NO 10286 CONFIDENCE standard compound; INTERNAL_ID 286; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 10259; ORIGINAL_PRECURSOR_SCAN_NO 10258 CONFIDENCE standard compound; INTERNAL_ID 286; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 10304; ORIGINAL_PRECURSOR_SCAN_NO 10302
isoxicam
A monocarboxylic acid amide that is piroxicam in which the pyrid-2-yl group is replaced by a 5-methyl-1,2-oxazol-3-yl group. A non-steroidal anti-inflammatory drug, it was withdrawn from the market in the 1980s following its association with cases of Stevens-Johnson syndrome. C78272 - Agent Affecting Nervous System > C241 - Analgesic Agent > C2198 - Nonnarcotic Analgesic D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents D002491 - Central Nervous System Agents > D000700 - Analgesics D000893 - Anti-Inflammatory Agents D018501 - Antirheumatic Agents
N-[4-(Cyanomethyl)phenyl]-N-[4-(trifluoromethoxy)phenyl]urea
2-Amino-3-({4-[4-(tert-butyl)-1,3-thiazol-2-yl]benzylidene}amino)but-2-enedinitrile
5(6)-1(2H)-Phthalazinonyl-4(1H)-benzimidazole-2-carbamate methyl ester
3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(2-thienyl)-, diethyl ester
6,13-Dihydro-7H-[1,3]dioxolo[4,5-i][1,3]dioxolo[4,5:4,5]benzo[1,2-c]phenanthridin-14-on|6,13-dihydro-7H-[1,3]dioxolo[4,5-i][1,3]dioxolo[4,5:4,5]benzo[1,2-c]phenanthridin-14-one|dihydro-norsanguinarinone|N-Demethyl-5,6-dihydrooxysanguinarine
2-C-(4-methoxyindol-3-ylmethyl)-beta-L-xylo-3-hexulofuranosonic acid gamma-lactone|4-methoxyascorbigen
3-[[2-Carboxy-2-(acetylamino)ethyl]thio]-4-hydroxynonanoic acid
2-acetamido-3-(3-hydroxy-2-isopropyl-4-methoxy-4-oxobutanoylthio)propanoic acid|JBIR-69
3-Phenyl-5-(3-methyl-2-butenyl)-6-methoxy-8-hydroxyisoquinoline-1(2H)-one
O1-(6-amino-[2]naphthyl)-beta-D-glucopyranuronic acid|O1-(6-Amino-[2]naphthyl)-beta-D-glucopyranuronsaeure
7-((S)-2,3-Dihydroxy-3-methyl-butyl)-6-methoxy-9-methyl-9H-[1,3]dioxolo[4,5-h]chinolin-8-on|7-((S)-2,3-dihydroxy-3-methyl-butyl)-6-methoxy-9-methyl-9H-[1,3]dioxolo[4,5-h]quinolin-8-one|Hydroxylunidin|Hydroxylunidine|Isoorixin|isoorixine
Oxocrebanin
8H-Benzo(g)-1,3-benzodioxolo(6,5,4-de)quinolin-8-one, 9,10-dimethoxy- is a natural product found in Xylopia aethiopica, Stephania hainanensis, and other organisms with data available.
Met-TRP
A dipeptide formed from L-methionine and L-tryptophan residues.
Oxonantenine
An oxoaporphine alkaloid isolated from Annona glabra and has been shown to exhibit acetylcholinesterase inhibitory activity.
S-Methylhomoglutathione
beta-Nicotinamide D-ribonucleotide
4-(4-chloro-3,5-dimethylphenoxy)-N-hydroxy-3-nitrobenzenecarboximidamide
n-methyl-4-(p-formylstyryl)pyridinium methylsulfate
[(3R)-1-(3-fluorophenyl)pyrrolidin-3-yl] 4-methylbenzenesulfonate
6-(p-Toluidino)-2-naphthalenesulfonic acid sodium salt
Sulotroban
C78275 - Agent Affecting Blood or Body Fluid > C1327 - Antiplatelet Agent D006401 - Hematologic Agents > D010975 - Platelet Aggregation Inhibitors D002317 - Cardiovascular Agents > D000889 - Anti-Arrhythmia Agents D006401 - Hematologic Agents > D005343 - Fibrinolytic Agents D050299 - Fibrin Modulating Agents
mtt formazan
D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents > D013778 - Tetrazolium Salts D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents > D005562 - Formazans
6-FLUORO-2-(3-(TRIFLUOROMETHYL)PHENYL)QUINOLINE-4-CARBOXYLIC ACID
8-FLUORO-2-(3-(TRIFLUOROMETHYL)PHENYL)QUINOLINE-4-CARBOXYLIC ACID
2,3(1H)-ISOQUINOLINEDICARBOXYLIC ACID, 6-BORONO-3,4-DIHYDRO-, 2-(1,1-DIMETHYLETHYL) 3-METHYL ESTER
6-AMINO-2-CHLORO-6,7,8,9-TETRAHYDRO-5H-BENZOCYCLOHEPTEN-5-OLHYDROCHLORIDE
4-(BROMO-METHOXYCARBONYL-METHYL)-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
2-(4-[5-(TRIFLUOROMETHYL)-2-PYRIDYL]PIPERAZINO)BENZALDEHYDE
SL-327
SL327 inhibits MEK1 and MEK2, with IC50 values of 180 nM and 220 nM, respectively.
1-(4-cyanophenyl)-5-(4-methylsulfanylphenyl)pyrazole-3-carboxylic acid
N-[(2S)-1-Phenyl-2-propanyl]-L-lysinamide dihydrochloride
4-Chloro-7-fluoro-6-[2-(4-morpholinyl)ethoxy]-3-quinolinecarbonit rile
4-Chloro-6-methoxy-7-(3-piperidin-1-yl-propoxy)-quinazoline
1-(1-ANTHRACENYLMETHYL)-4-PHENYL-1H-[1,2,3]TRIAZOLE
(4-(N-(4-Methoxybenzyl)-N-methylsulfamoyl)phenyl)boronic acid
5-Bromo-1-methyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole
Spiromustine
D000970 - Antineoplastic Agents > D018906 - Antineoplastic Agents, Alkylating > D009588 - Nitrogen Mustard Compounds C274 - Antineoplastic Agent > C186664 - Cytotoxic Chemotherapeutic Agent > C2842 - DNA Binding Agent
2-Methyl-2-propanyl 3-(6-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)-1- piperidinecarboxylate
2-Methyl-2-propanyl 3-(6-chloro-1H-pyrrolo[2,3-b]pyridin-2-yl)-1- piperidinecarboxylate
N-[4-(TRIFLUOROMETHYL)BENZOYL]-L-METHIONINYL HYDRAZIDE
Isoetharine mesylate
D019141 - Respiratory System Agents > D018927 - Anti-Asthmatic Agents > D001993 - Bronchodilator Agents D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents > D000322 - Adrenergic Agonists D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents Isoetharine (Isoetarine) mesylate is an orally active selective agonist of β-adrenergic receptors. Isoetharine mesylate is a catechol-like agent and catechol O-methyltransferase (COMT) mediates its methylation. Isoetharine mesylate can promote the production of cAMP which stimulates the relaxation of smooth muscle cells and can be used as an emphysema, bronchitis and bronchodilator[1][2].
tert-butyl 6-fluoro-4-oxospiro[3H-chromene-2,4-piperidine]-1-carboxylate
chlordiazepoxide hydrochloride
D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants > D006993 - Hypnotics and Sedatives D002492 - Central Nervous System Depressants > D014149 - Tranquilizing Agents > D014151 - Anti-Anxiety Agents D002491 - Central Nervous System Agents > D011619 - Psychotropic Drugs > D014149 - Tranquilizing Agents C78272 - Agent Affecting Nervous System > C29756 - Sedative and Hypnotic > C1012 - Benzodiazepine D018377 - Neurotransmitter Agents > D018682 - GABA Agents > D018757 - GABA Modulators C78272 - Agent Affecting Nervous System > C28197 - Antianxiety Agent
Ethyl 2-cyclopropyl-4-(4-fluorophenyl)-quinolyl-3-carboxylate
{[(4-Ethyl-2,3-Dioxo-1-Piperazinyl) Carbonyl]Amino}-4-Hydroxy-Benzene Acetic Acid
Pirifibrate
C78276 - Agent Affecting Digestive System or Metabolism > C29703 - Antilipidemic Agent > C98150 - Fibrate Antilipidemic Agent
Benzeneacetic acid, a-hydroxy-a-phenyl-, 2-(dimethylamino)ethylester, hydrochloride (9CI)
(2R)-2-[(4-Ethyl-2,3-dioxopiperazinyl)carbonylamino]-2-(4-hydroxyphenyl)acetic acid
4-(benzothiazol-2-ylazo)-2,4-dihydro-5-methyl-2-phenyl-3H-pyrazol-3-one
4-[(2,2-Dimethyl-4,6-dioxo-[1,3]dioxan-5-ylidenemethyl)-amino]-2-methoxy-benzoic acid methyl ester
O-(Phenylmethyl)-L-threonine phenylmethyl ester hydrochloride
2-(benzyloxycarbonyl)-3-(quinolin-4-yl)propanoic acid
ethyl 2-piperazine-4-(3-fluoro)phenyl thiazole-5-carboxylate
(9H-FLUOREN-9-YL)METHYL (4-OXOCYCLOHEXYL)CARBAMATE
n-[4-(trifluoromethyl)benzoyl]-l-methionine methyl ester
sulfachrysoidine
C254 - Anti-Infective Agent > C29739 - Sulfonamide Anti-Infective Agent
Boxidine
C78276 - Agent Affecting Digestive System or Metabolism > C29703 - Antilipidemic Agent
(2-(N-(4-Methoxybenzyl)-N-methylsulfamoyl)phenyl)boronic acid
1-(9-ANTHRACENYLMETHYL)-4-PHENYL-1H-[1,2,3]TRIAZOLE
N-(4-Chloro-3-((3-methyl-2-butenyl)oxy)phenyl)-2-methyl-3-furancarbothioamide
C471 - Enzyme Inhibitor > C1589 - Reverse Transcriptase Inhibitor > C97453 - Non-nucleoside Reverse Transcriptase Inhibitor D000890 - Anti-Infective Agents > D000998 - Antiviral Agents > D044966 - Anti-Retroviral Agents C254 - Anti-Infective Agent > C281 - Antiviral Agent
S-Ethyl glutathione
D020011 - Protective Agents > D011837 - Radiation-Protective Agents
Coumarin, 7-hydroxy-4-phenyl-8-(piperidinomethyl)-
[4-Amino-3-(4-methylphenyl)-2-sulfanylidene-5-thiazolyl]-(4-morpholinyl)methanone
N-benzyl-3-(5-chloro-1,3-benzoxazol-2-yl)pyridin-2-amine
2-(1H-benzimidazol-2-ylthio)-1-(2,3-dimethyl-1-indolyl)ethanone
N-(1,1-dioxo-3-thiolanyl)-N-(thiophen-2-ylmethyl)benzamide
N2-(4-fluorophenyl)-6-(3-methyl-2-benzofuranyl)-1,3,5-triazine-2,4-diamine
5-[1-[(4-Fluorophenyl)methyl]-3-pyrazolyl]-2-phenylthiazole
N-[1-methyl-3-(trifluoromethyl)-5-thieno[2,3-c]pyrazolyl]carbamic acid 2,2-dimethylpropyl ester
N-(5,5-dimethyl-7-oxo-4,6-dihydro-1,3-benzothiazol-2-yl)-2-(2,5-dioxo-1-pyrrolidinyl)acetamide
1-(1,3-Benzodioxol-5-ylmethylthio)-[1,2,4]triazolo[4,3-a]quinoline
3-(3-aminophenyl)-N-(3-chlorophenyl)pyrazolo[1,5-a]pyrimidin-5-amine
6-Amino-4-[2-(4-methoxyphenyl)ethyl]-1,7-dihydro-8H-imidazo[4,5-G]quinazolin-8-one
6-Chloro-4-(cyclohexylsulfanyl)-3-propylquinolin-2(1H)-one
2-[(Carboxycarbonyl)(1-naphthyl)amino]benzoic acid
3-{[(9-Cyano-9,10-dihydro-10-methylacridin-9-YL)carbonyl]amino}propanoic acid
Tert-Butyl 4-(3-Thiophen-2-Yl-1,2,4-Oxadiazol-5-Yl)piperidine-1-Carboxylate
[(2S,3R,4R,5R)-5-(3-carbamoylpyridin-1-ium-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate
({[(3E)-2-Oxo-2,7-dihydro-2,3-biindol-3(7H)-ylidene]amino}oxy)acetic acid
Nicotinamide ribotide
Nicotinamide ribotide (NMN) (CAS: 1094-61-7) is an important intermediate metabolite in the nicotinate and nicotinamide metabolism pathway. Mammals predominantly use nicotinamide rather than nicotinic acid as a precursor for NAD biosynthesis. Instead of the deamidation into nicotinic acid, nicotinamide is directly converted into NMN by nicotinamide phosphoribosyltransferase (NAMPT, EC 2.4.2.12). The enzyme nicotinamide mononucleotide adenylyltransferase (NMNAT, EC 2.7.7.1), which is a member of the nucleotidyltransferase alpha/beta-phosphodiesterase superfamily, catalyzes the reaction NMN + ATP <=> nicotinamide adenine dinucleotide (NAD) + PPi, representing the final step in the biosynthesis of NAD. NAD is a molecule that plays a fundamental role as a cofactor in cellular redox reactions. Thus NMN is an important metabolite for the maintenance of normal NAD biosynthesis. Circulating NMN levels may play an important role in regulating cell function in physiological and pathophysiological conditions (PMID: 15078171, 17983582). Nicotinamide ribotide (NMN) is an important intermediate metabolite in the nicotinate and nicotinamide metabolism pathway. Mammals predominantly use nicotinamide rather than nicotinic acid as a precursor for NAD biosynthesis. Instead of the deamidation to nicotinic acid, nicotinamide is directly converted to NMN by nicotinamide phosphoribosyltransferase (NAMPT, EC 2.4.2.12). The enzyme nicotinamide mononucleotide adenylyltransferase (NMNAT, EC 2.7.7.1), a member of the nucleotidyltransferase alpha/beta-phosphodiesterase superfamily, catalyzes the reaction NMN + ATP = Nicotinamide adenine dinucleotide (NAD) + PPi, representing the final step in the biosynthesis of NAD, a molecule playing a fundamental role as a cofactor in cellular redox reactions. Thus NMN is an important metabolite for the maintenance of normal NAD biosynthesis, and circulating NMN levels may play an important role in regulating cell function in physiological and pathophysiological conditions. (PMID: 15078171, 17983582) [HMDB]
N-[1-(3-methylbenzyl)-1H-pyrazol-3-yl]-1,3-benzodioxole-5-carboxamide
3-[1-(4-Carbamimidoylphenyl)triazol-4-yl]-4-methoxybenzenecarboximidamide
N(4)-(beta-N-acetyl-D-glucosaminyl)-L-asparagine zwitterion
Zwitterionic form of N(4)-(beta-N-acetyl-D-glucosaminyl)-L-asparagine arising from transfer of a proton from the carboxy to the amino group; major species at pH 7.3.
S-nitrosoglutathione(1-)
D019141 - Respiratory System Agents > D018927 - Anti-Asthmatic Agents > D001993 - Bronchodilator Agents D006401 - Hematologic Agents > D010975 - Platelet Aggregation Inhibitors > D026403 - S-Nitrosothiols D002491 - Central Nervous System Agents > D018696 - Neuroprotective Agents D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents D002317 - Cardiovascular Agents > D020030 - Nitric Oxide Donors D002317 - Cardiovascular Agents > D014665 - Vasodilator Agents D000890 - Anti-Infective Agents D020011 - Protective Agents
7-demethylmitomycin B
A member of the family of mitomycins that is mitomycin B in which the methoxy group on the quinone ring is replaced by a hydroxy group.
(2R,3S,9R)-5-acetyl-8,8-dimethyl-6-oxo-7,16-diazapentacyclo[9.6.1.02,9.03,7.015,18]octadeca-1(17),4,11(18),12,14-pentaen-4-olate
2-[2-[(3-Amino-3-carboxypropyl)amino]-2-oxoethyl]-4-(2-aminoethoxy)-2-hydroxy-4-oxobutanoic acid
2-Methyl-N-(5-methyl-3-isoxazolyl)-1,1,4-trioxo-3H-1$l^{6},2-benzothiazine-3-carboxamide
3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyl-2,3-dihydro-1H-tetrazole
2-Amino-5-[[1-(carboxymethylamino)-3-ethylsulfanyl-1-oxopropan-2-yl]amino]-5-oxopentanoic acid
4-[(1-Naphthalenylamino)-oxomethyl]benzene-1,3-dicarboxylic acid
Thr-Thr-Asp
A tripeptide composed of two L-threonine units and L-aspartic acid joined by peptide linkages.
4-methyl-N-[(2-methylquinolin-4-yl)methyl]-3-nitrobenzamide
4-[[6-methyl-2-(6-oxo-1-cyclohexa-2,4-dienylidene)-1H-pyrimidin-4-yl]amino]benzoic acid methyl ester
3-(2-fluorobenzyl)-5-(1H-indol-3-ylmethylene)-2,4-imidazolidinedione
6-(3-furanyl)-N-methyl-N-[(3-methyl-2-thiophenyl)methyl]-4-quinazolinamine
5-[(3-Methylanilino)methylidene]-1-(2-methylphenyl)-1,3-diazinane-2,4,6-trione
4-[[Dimethoxyphosphoryl(phenyl)methyl]amino]benzoic acid
2-[[anilino(oxo)methyl]amino]-N-(2-furanylmethyl)benzamide
8-Methoxy-1-(4-methoxyphenyl)-3-methyl-2-oxidobenzofuro[3,2-c]pyridin-2-ium
4-[1-[(3-Methoxy-4-methylphenyl)methyl]-2-benzimidazolyl]-1,2,5-oxadiazol-3-amine
3-[2-(4-Aminoanilino)-4-thiazolyl]-1-benzopyran-2-one
3-methyl-N-[[(2-methyl-5-quinolinyl)amino]-sulfanylidenemethyl]benzamide
N-(4-hydroxy-2-methyl-5-propan-2-ylphenyl)-4-methoxybenzenesulfonamide
ethyl 2-{[(E)-(4,4-dimethyl-2,6-dioxocyclohexyl)methylidene]amino}-5-methylthiophene-3-carboxylate
2-(2,4-dioxo-3-thiazolidinyl)-N-[4-(4-morpholinyl)phenyl]acetamide
4,5-Dimethoxy-2-[(1-oxo-2-thiophen-2-ylethyl)amino]benzoic acid methyl ester
2-[(6-methyl-1H-benzimidazol-2-yl)thio]-1-(2-methyl-1H-indol-3-yl)ethanone
5-(4-Methoxyanilino)-2-[(3-methylphenoxy)methyl]-4-oxazolecarbonitrile
(2R)-heptan-2-yl [(5-chloroquinolin-8-yl)oxy]acetate
[4-[(E)-(pyridine-2-carbonylhydrazinylidene)methyl]phenyl] furan-2-carboxylate
(1Z)-1-[(6aR,11aS,11bR)-7,7-dimethyl-9,11-dioxo-2,6a,7,11,11a,11b-hexahydro-6H-pyrrolo[1,2:2,3]isoindolo[4,5,6-cd]indol-10(9H)-ylidene]ethanolate
3-(4-Methylphenyl)-5-oxo-8-thiazolo[2,3-b]quinazolinecarboxamide
5,7-dimethyl-3-[3-(trifluoromethyl)phenyl]azo-1H-pyrazolo[1,5-a]pyrimidin-2-one
N-[2-[(4,5-dimethyl-1,2,4-triazol-3-yl)thio]-1-oxoethyl]-4-methoxybenzohydrazide
N-[(1E)-(2,5-dimethyl-1-phenyl-1H-pyrrol-3-yl)methylene]-3-fluorobenzohydrazide
Met-Ala-Asp
A tripeptide composed of L-methionine, L-alanine and L-aspartic acid joined in sequence by peptide linkages.
N-[(E)-(1-methylindol-3-yl)methylideneamino]-2,3-dihydro-1,4-benzodioxine-3-carboxamide
(2S)-heptan-2-yl [(5-chloroquinolin-8-yl)oxy]acetate
[(2R,3S,4R,5S)-5-(3-carbamoylpyridin-1-ium-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate
3-(1H-indol-3-yl)-2-[[(Z)-3-pyridin-2-ylprop-2-enoyl]amino]propanoic acid
2-(1H-benzimidazol-2-yl)-4-(3,4-dimethoxyphenyl)-3-oxobutanenitrile
[7-[(3-Cyanophenyl)sulfonylamino]-4-methylindol-3-ylidene]methylideneazanide
[(4S,6S,7R)-11,13-dihydroxy-7-methoxy-12-methyl-10-oxo-2,5-diazatetracyclo[7.4.0.02,7.04,6]trideca-1(13),8,11-trien-8-yl]methyl carbamate
[(4S,6S,7R)-7,11,13-trihydroxy-5,12-dimethyl-10-oxo-2,5-diazatetracyclo[7.4.0.02,7.04,6]trideca-1(13),8,11-trien-8-yl]methyl carbamate
(2S)-2-(4-ethyl-1-methyl-6-oxopyrimidin-2-yl)sulfanyl-N-(4-fluorophenyl)propanamide
2-Benzyl-4-methyl-4,4A-dihydro-1H-(1,3,5)triazino(1,2-A)quinoline-1,3,6(2H,5H)-trione
N-Acetylglucosaminylasparagine
An N(4)-glycosyl-L-asparagine having (beta-N-acetyl-D-glucosaminyl as the glycosyl component.
S-Formylglutathione
A S-acylglutathione in which the acyl group specified is formyl.
5-[(e)-Caffeoyl]shikimate
A hydroxy monocarboxylic acid anion that is the conjugate base of 5-[(E)-caffeoyl]shikimic acid. Major structure at pH 7.3
(S)-malyl N-acetyl-alpha-D-glucosaminide(2-)
A carbohydrate acid derivative anion obtained by deprotonation of both carboxy groups of (S)-malyl N-acetyl-alpha-D-glucosaminide; major species at pH 7.3.
trifluralin
D050258 - Mitosis Modulators > D050256 - Antimitotic Agents > D050257 - Tubulin Modulators D000970 - Antineoplastic Agents > D050256 - Antimitotic Agents D010575 - Pesticides > D006540 - Herbicides D016573 - Agrochemicals
alpha-cyclopiazonate
An organic anion that is the conjugate base of alpha-cyclopiazonic acid; major species at pH 7.3.
N-(2-Methoxybenzyl)-2-(4-chloro-2,5-dimethoxyphenyl)ethanamine
AMPA receptor modulator-3
AMPA receptor modulator-3 is an allosteric AMPA receptor modulator (EC50: 4.4 μM). AMPA receptor modulator-3 can be used in the research of mammalian nervous system, such as learning and memory[1][2].
Glutathione ethyl ester
Glutathione ethyl ester is a cell-permeable GSH donor and provides an efficient supply of GSH to the oocyte. Glutathione ethyl ester shows positive effect on the in vitro production of embryos by enhancement of the antioxidative defense[1].
LAS101057
LAS101057 is a potent, selective, and orally efficacious A2B receptor antagonist.
Longdaysin
Longdaysin is a inhibitor of the Wnt/β-catenin signaling pathway, which exerts antitumor effect through blocking CK1δ/ε-dependent Wnt signaling. Longdaysin inhibits CK1α, CK1δ, CDK7, and ERK2 with IC50s of? 5.6 μM, 8.8 μM, 29 μM, and 52 μM, respectively[1][2].
N-Formyl-Met-Ala-Ser
N-Formyl-Met-Ala-Ser is a peptide, binds to formyl peptide receptors on neutrophils.
NL-1
NL-1 is a mitoNEET inhibitor with antileukemic effect. NL-1 inhibits REH and REH/Ara-C cells growth with IC50s of 47.35 μM and 56.26 μM, respectively. NL-1-mediated death in leukemic cells requires the activation of the autophagic pathway[1].
