Exact Mass: 300.1110016
Exact Mass Matches: 300.1110016
Found 500 metabolites which its exact mass value is equals to given mass value 300.1110016,
within given mass tolerance error 0.05 dalton. Try search metabolite list with more accurate mass tolerance error
0.01 dalton.
Farrerol
Farrerol is an organic molecular entity. It has a role as a metabolite. (S)-2,3-Dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-6,8-dimethyl-4-benzopyrone is a natural product found in Rhododendron spinuliferum, Wikstroemia canescens, and other organisms with data available. Farrerol is a bioactive constituent of Rhododendron, with broad activities such as anti-oxidative, anti-inflammatory, anti-tumor, neuroprotective and hepatoprotective effects[1][2][3][4][5][6]. Farrerol is a bioactive constituent of Rhododendron, with broad activities such as anti-oxidative, anti-inflammatory, anti-tumor, neuroprotective and hepatoprotective effects[1][2][3][4][5][6].
Salidroside
Salidroside is a glycoside. Salidroside is a natural product found in Plantago australis, Plantago coronopus, and other organisms with data available. See also: Sedum roseum root (part of); Rhodiola crenulata root (part of). Salidroside is a prolyl endopeptidase inhibitor. Salidroside alleviates cachexia symptoms in mouse models of cancer cachexia via activating mTOR signalling. Salidroside protects dopaminergic neurons by enhancing PINK1/Parkin-mediated mitophagy. Salidroside is a prolyl endopeptidase inhibitor. Salidroside alleviates cachexia symptoms in mouse models of cancer cachexia via activating mTOR signalling. Salidroside protects dopaminergic neurons by enhancing PINK1/Parkin-mediated mitophagy.
Cnidilin
Cnidilin is a member of psoralens. Cnidilin is a natural product found in Hansenia forbesii, Zanthoxylum americanum, and other organisms with data available.
Phellopterin
Phellopterin is a member of the class of compounds known as 5-methoxypsoralens. 5-methoxypsoralens are psoralens containing a methoxy group attached at the C5 position of the psoralen group. Phellopterin is practically insoluble (in water) and an extremely weak basic (essentially neutral) compound (based on its pKa). Phellopterin can be found in lemon, lime, and wild celery, which makes phellopterin a potential biomarker for the consumption of these food products. Phellopterin is a non-carcinogenic (not listed by IARC) potentially toxic compound. The furocoumarin 8-methoxypsoralen is carcinogenic to humans, and possibly 5-methoxypsoralen as well (L135). There is some evidence from mouse studies that other furocoumarins are carcinogenic when combined with exposure to UVA radiation (A15105). The SKLM regards the additional risk of skin cancer arising from the consumption of typical quantities of furocoumarin-containing foods, which remain significantly below the range of phototoxic doses, as insignificant. However, the consumption of phototoxic quantities cannot be ruled out for certain foods, particularly celery and parsnips, that may lead to significant increases in furocoumarin concentrations, depending on the storage, processing and production conditions (L2157) Furocoumarin photochemotherapy is known to induce a number of side-effects including erythema, edema, hyperpigmentation, and premature aging of skin. All photobiological effects of furocoumarins result from their photochemical reactions. Because many dietary or water soluble furocoumarins are strong inhibitors of cytochrome P450s, they will also cause adverse drug reactions when taken with other drugs. It activates adrenaline-induced lipolysis and activate ACTH-induced lipolysis (L579) (T3DB). Phellopterin is a natural product isolated from Angelica dahurica. Phellopterin reduces TNF-alpha-induced VCAM-1 expression through regulation of the Akt and PKC pathway, which contributes to inhibit the adhesion of monocytes to endothelium[1]. Phellopterin is a natural product isolated from Angelica dahurica. Phellopterin reduces TNF-alpha-induced VCAM-1 expression through regulation of the Akt and PKC pathway, which contributes to inhibit the adhesion of monocytes to endothelium[1]. Phellopterin is a natural product isolated from Angelica dahurica. Phellopterin reduces TNF-alpha-induced VCAM-1 expression through regulation of the Akt and PKC pathway, which contributes to inhibit the adhesion of monocytes to endothelium[1].
Desmedipham
CONFIDENCE standard compound; INTERNAL_ID 3738
Homopisatin
Isolated from leaves or cotyledons of Lens culinaris (lentil) and Trifolium pratense (red clover). Homopisatin is found in many foods, some of which are lentils, herbs and spices, tea, and pulses. Homopisatin is found in herbs and spices. Homopisatin is isolated from leaves or cotyledons of Lens culinaris (lentil) and Trifolium pratense (red clover).
5-Nitro-2-(3-phenylpropylamino)benzoic acid
D006133 - Growth Substances > D043924 - Angiogenesis Modulating Agents D000970 - Antineoplastic Agents > D020533 - Angiogenesis Inhibitors D006133 - Growth Substances > D006131 - Growth Inhibitors
Methylnissolin
Methylnissolin is a member of pterocarpans. Methylnissolin is a natural product found in Lathyrus nissolia and Dalbergia odorifera with data available. Methylnissolin is found in alfalfa. Methylnissolin is isolated from Medicago sativa (alfalfa). Isolated from Medicago sativa (alfalfa). Methylnissolin is found in alfalfa and pulses. Methylnissolin (Astrapterocarpan), isolated from Astragalus membranaceus, inhibits platelet-derived growth factor (PDGF)-BB-induced cell proliferation with an IC50 of 10 μM. Methylnissolin inhibits PDGF-BB-induced phosphorylation of extracellular signal-regulated kinase 1/2 (ERIC1/2) mitogen-activated protein (MAP) kinase. Methylnissolin inhibits PDGF-BB-induced vascular smooth muscle cell proliferation by inhibition of the ERK1/2 MAP kinase cascade[1]. Methylnissolin (Astrapterocarpan), isolated from Astragalus membranaceus, inhibits platelet-derived growth factor (PDGF)-BB-induced cell proliferation with an IC50 of 10 μM. Methylnissolin inhibits PDGF-BB-induced phosphorylation of extracellular signal-regulated kinase 1/2 (ERIC1/2) mitogen-activated protein (MAP) kinase. Methylnissolin inhibits PDGF-BB-induced vascular smooth muscle cell proliferation by inhibition of the ERK1/2 MAP kinase cascade[1]. Methylnissolin (Astrapterocarpan), isolated from Astragalus membranaceus, inhibits platelet-derived growth factor (PDGF)-BB-induced cell proliferation with an IC50 of 10 μM. Methylnissolin inhibits PDGF-BB-induced phosphorylation of extracellular signal-regulated kinase 1/2 (ERIC1/2) mitogen-activated protein (MAP) kinase. Methylnissolin inhibits PDGF-BB-induced vascular smooth muscle cell proliferation by inhibition of the ERK1/2 MAP kinase cascade[1].
Phenmedipham
CONFIDENCE standard compound; INTERNAL_ID 3779 D010575 - Pesticides > D006540 - Herbicides D016573 - Agrochemicals
Flavokawain C
2,4-Dihydroxy-4,6-dimethoxychalcone is found in beverages. 2,4-Dihydroxy-4,6-dimethoxychalcone is found in kava (Piper methysticum). FDA advises against use of kava in food due to potential risk of severe liver damage (2002 Flavokawain C is a member of chalcones. 2,4-Dihydroxy-4,6-dimethoxychalcone is a natural product found in Argyrochosma dealbata, Piper methysticum, and other organisms with data available. Flavokawain C is a natural chalcone found in Kava root. Flavokawain C exerts cytotoxicity against human cancer cell lines, with an IC50 of 12.75 μM for HCT 116 cells[1]. Flavokawain C is a natural chalcone found in Kava root. Flavokawain C exerts cytotoxicity against human cancer cell lines, with an IC50 of 12.75 μM for HCT 116 cells[1].
Phelloterin
Phellopterin is a member of psoralens. Phellopterin is a natural product found in Amyris pinnata, Heracleum candolleanum, and other organisms with data available. A naturally occurring furanocoumarin found in roots of Angelica dahurica and in Seseli elatum (L579). Furocoumarins, are phototoxic and photocarcinogenic. They intercalate DNA and photochemically induce mutations. Furocoumarins are botanical phytoalexins found to varying extents in a variety of vegetables and fruits, notably citrus fruits. The levels of furocoumarins present in our diets, while normally well below that causing evident acute phototoxicity, do cause pharmacologically relevant drug interactions. Some are particularly active against cytochrome P450s. For example, in humans, bergamottin and dihydroxybergamottin are responsible for the grapefruit juice effect, in which these furanocoumarins affect the metabolism of certain drugs. Phellopterin is a natural product isolated from Angelica dahurica. Phellopterin reduces TNF-alpha-induced VCAM-1 expression through regulation of the Akt and PKC pathway, which contributes to inhibit the adhesion of monocytes to endothelium[1]. Phellopterin is a natural product isolated from Angelica dahurica. Phellopterin reduces TNF-alpha-induced VCAM-1 expression through regulation of the Akt and PKC pathway, which contributes to inhibit the adhesion of monocytes to endothelium[1]. Phellopterin is a natural product isolated from Angelica dahurica. Phellopterin reduces TNF-alpha-induced VCAM-1 expression through regulation of the Akt and PKC pathway, which contributes to inhibit the adhesion of monocytes to endothelium[1].
Sativanone
Sativanone is found in alfalfa. Sativanone is isolated from Medicago sativa (alfalfa) leaves innoculated with the fungus Helminthosporium cabonum. Isolated from Medicago sativa (alfalfa) leaves innoculated with the fungus Helminthosporium cabonum. Sativanone is found in alfalfa and pulses.
8-Hydroxy-3,9-dimethoxypterocarpan
8-Hydroxy-3,9-dimethoxypterocarpan is found in green vegetables. 8-Hydroxy-3,9-dimethoxypterocarpan is from Pterocarpus soyauxii. From Pterocarpus soyauxii. 8-Hydroxy-3,9-dimethoxypterocarpan is found in green vegetables.
3-Hydroxy-2,9-dimethoxypterocarpan
3-Hydroxy-2,9-dimethoxypterocarpan is found in common pea. 3-Hydroxy-2,9-dimethoxypterocarpan is isolated from root crowns of Pisum sativum (pea). Isolated from root crowns of Pisum sativum (pea). 3-Hydroxy-2,9-dimethoxypterocarpan is found in green vegetables and common pea.
4,4'-Dihydroxy-2',6'-dimethoxychalcone
4,4-Dihydroxy-2,6-dimethoxychalcone is found in alcoholic beverages. 4,4-Dihydroxy-2,6-dimethoxychalcone is isolated from Humulus lupulus (hops). Isolated from Humulus lupulus (hops). 4,4-Dihydroxy-2,6-dimethoxychalcone is found in alcoholic beverages.
(2E)-1-(2,3-dihydroxy-4,6-dimethoxyphenyl)-3-phenylprop-2-en-1-one
2-Propen-1-one, 1-(2,6-dihydroxy-3,4-dimethoxyphenyl)-3-phenyl-, (E)-; (2E)-1-(2,6-Dihydroxy-3,4-dimethoxyphenyl)-3-phenyl-2-propen-1-one
Heliannone A
Heliannone A is found in fats and oils. Heliannone A is a constituent of Helianthus annuus (sunflower) Constituent of Helianthus annuus (sunflower). Heliannone A is found in sunflower and fats and oils.
2-(3-Hydroxyphenyl)ethanol 1'-glucoside
2-(3-Hydroxyphenyl)ethanol 1-glucoside is found in fruits. 2-(3-Hydroxyphenyl)ethanol 1-glucoside is a constituent of Sambucus nigra (elderberry). Constituent of Sambucus nigra (elderberry). 2-(3-Hydroxyphenyl)ethanol 1-glucoside is found in fruits.
5,7-Dihydroxy-4'-methoxy-8-methylisoflavanone
5,7-Dihydroxy-4-methoxy-8-methylisoflavanone is found in cereals and cereal products. 5,7-Dihydroxy-4-methoxy-8-methylisoflavanone is a constituent of the flowers of Amaranthus caudatus (love-lies-bleeding). Constituent of the flowers of Amaranthus caudatus (love-lies-bleeding). 5,7-Dihydroxy-4-methoxy-8-methylisoflavanone is found in cereals and cereal products and green vegetables.
5,7-Dihydroxy-4'-methoxy-8-methylflavanone
5,7-Dihydroxy-4-methoxy-8-methylflavanone is found in cereals and cereal products. 5,7-Dihydroxy-4-methoxy-8-methylflavanone is a constituent of the flowers of Amaranthus caudatus (love-lies-bleeding). Constituent of the flowers of Amaranthus caudatus (love-lies-bleeding). 5,7-Dihydroxy-4-methoxy-8-methylflavanone is found in cereals and cereal products and green vegetables.
4-Methoxybenzyl glucoside
4-Methoxybenzyl glucoside is found in fruits. 4-Methoxybenzyl glucoside is present in fennel and marrow (flowers). Present in fennel and marrow (flowers). 4-Methoxybenzyl glucoside is found in herbs and spices and fruits.
1-(2-hydroxy-4,6-dimethoxyphenyl)-3-(2-hydroxyphenyl)prop-2-en-1-one
7-hydroxy-6-methoxy-3-(4-methoxyphenyl)-3,4-dihydro-2H-1-benzopyran-4-one
3-Hydroxy-4,9-dimethoxypterocarpan
3-Hydroxy-4,9-dimethoxypterocarpan is found in green vegetables. 3-Hydroxy-4,9-dimethoxypterocarpan is a constituent of Trifolium repens (white clover).
Heliannone B
Heliannone B is found in fats and oils. Heliannone B is a constituent of Helianthus annuus (sunflower)
Promazine 5-sulfoxide
Promazine 5-sulfoxide is only found in individuals that have used or taken Promazine. Promazine 5-sulfoxide is a metabolite of Promazine. Promazine 5-sulfoxide belongs to the family of Phenothiazines. These are polycyclic aromatic compounds containing a phenothiazine moiety, which is a linear tricyclic system that consists of a two benzene rings joined by a para-thiazine ring.
1-{2-[(3-Ethylphenyl)amino]-2-oxoethyl}-6-oxo-1,6-dihydropyridine-3-carboxylic acid
Desmethylranitidine
C12H20N4O3S (300.12560500000006)
Etifoxine
D002492 - Central Nervous System Depressants > D014149 - Tranquilizing Agents > D014151 - Anti-Anxiety Agents D002491 - Central Nervous System Agents > D011619 - Psychotropic Drugs > D014149 - Tranquilizing Agents D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants C78272 - Agent Affecting Nervous System > C28197 - Antianxiety Agent N - Nervous system > N05 - Psycholeptics > N05B - Anxiolytics Etifoxine, a non-benzodiazepine GABAergic compound, is a positive allosteric modulator of α1β2γ2 and α1β3γ2 subunit-containing GABAA receptors. Etifoxine reveals anxiolytic and anticonvulsant properties in rodents[1][2][3].
Salidroside
Salidroside is a member of the class of compounds known as O-glycosyl compounds. O-glycosyl compounds are glycoside in which a sugar group is bonded through one carbon to another group via a O-glycosidic bond. Salidroside is soluble (in water) and a very weakly acidic compound (based on its pKa). Salidroside can be found in olive, which makes salidroside a potential biomarker for the consumption of this food product. Salidroside (Rhodioloside) is a glucoside of tyrosol found in the plant Rhodiola rosea. It is thought to be one of the compounds responsible for the antidepressant and anxiolytic actions of this plant, along with rosavin. Salidroside may be more active than rosavin, even though many commercially marketed Rhodiola rosea extracts are standardised for rosavin content rather than salidroside . Salidroside is a prolyl endopeptidase inhibitor. Salidroside alleviates cachexia symptoms in mouse models of cancer cachexia via activating mTOR signalling. Salidroside protects dopaminergic neurons by enhancing PINK1/Parkin-mediated mitophagy. Salidroside is a prolyl endopeptidase inhibitor. Salidroside alleviates cachexia symptoms in mouse models of cancer cachexia via activating mTOR signalling. Salidroside protects dopaminergic neurons by enhancing PINK1/Parkin-mediated mitophagy.
3-Butyl-1-(hydroxymethyl)-1-(4-methylphenyl)sulfonylurea
C13H20N2O4S (300.11437200000006)
2-(Diethylamino)ethyl 4-amino-5-chloro-2-methoxybenzoate
Farrerol
Farrerol is an organic molecular entity. It has a role as a metabolite. (S)-2,3-Dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-6,8-dimethyl-4-benzopyrone is a natural product found in Rhododendron spinuliferum, Wikstroemia canescens, and other organisms with data available. Farrerol is a natural product found in Daphne aurantiaca, Rhododendron farrerae, and Rhododendron dauricum with data available. Farrerol is a bioactive constituent of Rhododendron, with broad activities such as anti-oxidative, anti-inflammatory, anti-tumor, neuroprotective and hepatoprotective effects[1][2][3][4][5][6]. Farrerol is a bioactive constituent of Rhododendron, with broad activities such as anti-oxidative, anti-inflammatory, anti-tumor, neuroprotective and hepatoprotective effects[1][2][3][4][5][6].
4,7-i--ethylnaringenin
(2S)-5-hydroxy-4,7-dimethoxyflavanone is a 5-hydroxy-4,7-dimethoxyflavanone that has (S)-configuration. It is a 5-hydroxy-4,7-dimethoxyflavanone and a (2S)-flavan-4-one. It is functionally related to a (S)-naringenin. (S)-5-Hydroxy-7-methoxy-2-(4-methoxyphenyl)chroman-4-one is a natural product found in Sarcandra hainanensis, Vitex quinata, and other organisms with data available. 4',?7-?Di-?O-?methylnaringenin is a flavonoid found in Renealmia alpinia[1]. 4',?7-?Di-?O-?methylnaringenin is a flavonoid found in Renealmia alpinia[1].
Naringenin 7,4-dimethyl ether
4',?7-?Di-?O-?methylnaringenin is a flavonoid found in Renealmia alpinia[1]. 4',?7-?Di-?O-?methylnaringenin is a flavonoid found in Renealmia alpinia[1].
BRASUDOL
(3Z,6E)-1-Bromo-2-hydroxy-3,7,11-trimethyldodeca-3,6,10-triene
[1R-(1alpha,4alpha,4aalpha,8abeta)]-4-Bromo-1,2,3,4,4a,5,8,8a-octahydro-1,4a-dimethyl-7-(1-methylethyl)-1-naphthalenol
Isobrasudol
2,4-Dihydroxy-3,6-dimethoxychalcone
2,4-Dihydroxy-3,6-dimethoxychalcone is a natural product found in Bistorta officinalis, Persicaria amphibia, and other organisms with data available.
Odoriflavene
Odoriflavene is a natural product found in Dalbergia odorifera with data available.
Methylliderone
Melilotocarpan A
Pashanone
Pashanone is a natural product found in Onychium siliculosum, Lindera erythrocarpa, and other organisms with data available.
Methylnissolin
Methylnissolin (Astrapterocarpan), isolated from Astragalus membranaceus, inhibits platelet-derived growth factor (PDGF)-BB-induced cell proliferation with an IC50 of 10 μM. Methylnissolin inhibits PDGF-BB-induced phosphorylation of extracellular signal-regulated kinase 1/2 (ERIC1/2) mitogen-activated protein (MAP) kinase. Methylnissolin inhibits PDGF-BB-induced vascular smooth muscle cell proliferation by inhibition of the ERK1/2 MAP kinase cascade[1]. Methylnissolin (Astrapterocarpan), isolated from Astragalus membranaceus, inhibits platelet-derived growth factor (PDGF)-BB-induced cell proliferation with an IC50 of 10 μM. Methylnissolin inhibits PDGF-BB-induced phosphorylation of extracellular signal-regulated kinase 1/2 (ERIC1/2) mitogen-activated protein (MAP) kinase. Methylnissolin inhibits PDGF-BB-induced vascular smooth muscle cell proliferation by inhibition of the ERK1/2 MAP kinase cascade[1]. Methylnissolin (Astrapterocarpan), isolated from Astragalus membranaceus, inhibits platelet-derived growth factor (PDGF)-BB-induced cell proliferation with an IC50 of 10 μM. Methylnissolin inhibits PDGF-BB-induced phosphorylation of extracellular signal-regulated kinase 1/2 (ERIC1/2) mitogen-activated protein (MAP) kinase. Methylnissolin inhibits PDGF-BB-induced vascular smooth muscle cell proliferation by inhibition of the ERK1/2 MAP kinase cascade[1].
Phenmedipham
D010575 - Pesticides > D006540 - Herbicides D016573 - Agrochemicals CONFIDENCE standard compound; EAWAG_UCHEM_ID 94
Etifoxine
D002492 - Central Nervous System Depressants > D014149 - Tranquilizing Agents > D014151 - Anti-Anxiety Agents D002491 - Central Nervous System Agents > D011619 - Psychotropic Drugs > D014149 - Tranquilizing Agents D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants C78272 - Agent Affecting Nervous System > C28197 - Antianxiety Agent N - Nervous system > N05 - Psycholeptics > N05B - Anxiolytics Etifoxine, a non-benzodiazepine GABAergic compound, is a positive allosteric modulator of α1β2γ2 and α1β3γ2 subunit-containing GABAA receptors. Etifoxine reveals anxiolytic and anticonvulsant properties in rodents[1][2][3].
7-[(4-methoxyphenyl)methyl]-1,3-dimethylpurine-2,6-dione
C15H16N4O3 (300.12223459999996)
Desmethylranitidine
C12H20N4O3S (300.12560500000006)
A member of the class of furans that is a metabolite of ranitidine in rats and humans.
(E)-1-(3,4-dihydroxy-2,6-dimethoxyphenyl)-3-phenylprop-2-en-1-one
Me-SPA6C
C14H20O5S (300.10313900000006)
Literature spectrum; CONFIDENCE Tentative identification: isomers possible (Level 3); Could be alkyl homologue of given structure; Digitised from figure: approximate intensities
(Z)-3-(7-hydroxy-5-methoxyphenyl)-2-(6-hydroxy-4-methoxyphenyl)acrylaldehyde|erythraddison B
10-[2-Methyl-3-(methylamino)propyl]-10H-phenothiazin-3-ol
(3alpha, 4beta, 5beta)-form-3-Bromo-11-eudesmen-5-ol
Me ester,7-Me ether-3,7-Dihydroxy-1,9-dimethyl-2-dibenzofurancarboxylic acid|methyl 7-O-methylnorascomatate
(2beta, 4beta, 5beta)-form-2-Bromo-11-eudesmen-5-ol
1-(2,4-dihydroxy-3-methoxyphenyl)-3-(4-methoxyphenyl)-2-propene-1-one|kukulkanin A
1-[2-(Hydroxymethyl)-2-propenyl]-3-methoxydibenzofuran-2,7-diol
1-<(3S*,3aR*,4R*,7S*,7aS*)-7-bromo-7a-methyl-3-(1-methylethyl)octahydro-1H-inden-4-yl>ethanone|1-[(3S*,3aR*,4R*,7S*,7aS*)-7-bromo-7a-methyl-3-(1-methylethyl)octahydro-1H-inden-4-yl]ethanone|7-Acetyl-4-bromo-1-isopropyl-3alpha-methylindane
10-Me ether-8-Methyltoralactone|8-methyltoralactone 10-methylether
2,4,7-Tri-Me ether-2,3,4,6,7-Pentahydroxyphenanthrene|3,6-Dihydroxy-2,4,7-trimethoxyphenanthren
6-methoxy-5-(4-hydroxy-3-methyl-but-2-enyl)-angelicin|6-methoxy-5-(4-hydroxy-3-methylbut-2-enyl)angelicin
4-[2-(3,3-Dimethyloxiranyl)ethoxy]-7H-furo[3,2-g][1]benzopyran-7-one
6-{5-[(5E)-oct-5-en-7-ynyl]thiophen-2-yl}hex-5-ynoic acid
2-amino-N-(5,6,8-trihydroxy-3-methyl-1-oxo-3,4,4a,5,6,7-hexahydroisochromen-4-yl)propanamide
Phenol, 2-methoxy-5-[(1E)-2-(7-methoxy-1,3-benzodioxol-5-yl)ethenyl]-
6-Hydroxy-5,4-dimethoxy-flavanon|6-hydroxy-5-methoxy-2-(4-methoxy-phenyl)-chroman-4-one
(E)-4,5-dimethoxy-2-(1-methoxy-3-phenylallylidene)cyclopent-4-ene-1,3-dione|4,5-dimethoxy-[(E)-2-(1-methoxy-3-phenyl-2-propen-1-ylidene)]-4-cyclopentene-1,3-dione|methyl linderone|Methyl-linderon|Methyllinderone
1beta-bromo-cycloopposita-4beta-ol|5-bromo-1-isopropyl-2,5a-dimethyl-decahydro-cyclopropa[a]inden-2-ol|5a,7a(H)-1beta-bromo-6,8-cycloeudesma-4beta-ol|6,8-cycloeudesmane
5,10-dihydroxy-8-methoxy-2-propyl-4H-naphtho<1,2-b>pyran-4-one|5,10-dihydroxy-8-methoxy-2-propyl-4H-naphtho[1,2-b]pyran-4-one
3,4-Dihydro-4-(4-methoxyphenyl)-5-hydroxy-7-methoxycoumarin
2R*,4R*-8-hydroxyethyl-7,4-dihydroxy-4,2-epoxyflavane
(6aR,11aR)-9-hydroxy-1,3-dimethoxypterocarpan|erythbidin D
(2S)-2,3-dihydro-2-(3-hydroxy-5-methoxyphenyl)-7-methoxy-4H-1-benzopyran-4-one|(2S)-3-hydroxy-5,7-dimethoxyflavanone
Pterolinus A
A member of the class of 1-benzofurans that is 1-benzofuran substituted by a hydroxy group at position 5, a methoxy group at position 6, a 3-hydroxy-4-methoxyphenyl group at position 3 and a methyl group at position 2. Isolated from Pterocarpus santalinus, it exhibits anti-inflammatory activity.
1-(2,4-dihydroxyphenyl)-3-(2,3-dimethoxyphenyl)prop-2-en-1-one
1-(2,4-dihydroxyphenyl)-3-(3,4-dimethoxyphenyl)prop-2-en-1-one
2-Propen-1-one, 1-(2,4-dihydroxy-3,6-dimethoxyphenyl)-3-phenyl-,(E)-
2,6-Dimethoxy-3-(3-oxo-3-phenylpropyl)-1,4-benzoquinone
rel-(1aR,2R,3R,7bS)-1a,2,3,7b-tetrahydro-2,3-dihydroxy-5-(2-phenylethyl)-7H-oxireno[f][1]benzopyran-7-one
3-(3,4-Dihydroxyphenyl)-6-methoxy-8-hydroxy-3,4-dihydronaphthalene-1(2H)-one
(2S)-3,4-methylenedioxy-5-methoxy-7-hydroxyflavan|eriocaulin A
5,7-Dihydroxy-2-(4-methoxy-phenyl)-6-methyl-chroman-4-on|5,7-dihydroxy-2-(4-methoxy-phenyl)-6-methyl-chroman-4-one|5,7-dihydroxy-6-methyl-4-methoxydihydroflavone
(1R)-1-O-(beta-D-glucopyranosyl)-1-phenylethylene glycol|2-O-beta-glucosyl-(1R)-phenylethylene glycol|crenulatanoside C
5-Acetoxy-2,8,8-trimethyl-4H,8H-benzo[1,2-b:3,4-b]dipyran-4-one
7-Me,4,5-methylene ether-2,4,5,7-Tetrahydroxyflavan|7-methoxy-2-hydroxy-4,5-methylenedioxyflavan
7-hydroxy-5,6-dimethoxy-2-phenyl-chroman-4-one|7-hydroxy-5,6-dimethoxyflavanone
(2R,4S)-2,4-dihydroxy-2H-furan-(3,4:8,7)-flavan-4-ol
(-)-7,8-dihydro-3,6-dihydroxy-1,7,7,8-tetramethyl-5h-furo-[2,3:5,6]naphtho[1,8-bc]furan-5-one
8-(1,1-Diemthylallyloxy)bergapten|8-(1,1-Dimethylallyloxy)-bergapten|8-(1,1-dimethylallyloxy)bergapten|9-(1,1-dimethyl-allyloxy)-4-methoxy-furo[3,2-g]chromen-7-one|9-[(2-methylbut-3-en-2-yl)oxy]-4-methoxy-7H-furo[3,2-g]chromen-7-one
(R)-(-)-pyridindolol K2|(R)-(?)-pyridindolol K2|16-O-acetylpyridindolol
4-(3,3-dimethyl-oxiranylmethyl)-9-methoxy-furo[3,2-g]chromen-7-one
3,7-dimethoxy-1,9-dimethyldibenzofuran-2-carboxylic acid|ascomatic acid|Di-Me ether-3,7-Dihydroxy-1,9-dimethyl-2-dibenzofurancarboxylic acid
Phellopterin
Phellopterin is a natural product isolated from Angelica dahurica. Phellopterin reduces TNF-alpha-induced VCAM-1 expression through regulation of the Akt and PKC pathway, which contributes to inhibit the adhesion of monocytes to endothelium[1]. Phellopterin is a natural product isolated from Angelica dahurica. Phellopterin reduces TNF-alpha-induced VCAM-1 expression through regulation of the Akt and PKC pathway, which contributes to inhibit the adhesion of monocytes to endothelium[1]. Phellopterin is a natural product isolated from Angelica dahurica. Phellopterin reduces TNF-alpha-induced VCAM-1 expression through regulation of the Akt and PKC pathway, which contributes to inhibit the adhesion of monocytes to endothelium[1].
1-(beta-Carbolin-1-yl)-3,4,5-trihydroxy-1-pentanone
(+-)-5-Hydroxy-4-7-dimethoxy-flavanon|5-Hydroxy-7,4-dimethoxyisoflavanon|5-hydroxy-7-methoxy-3-(4-methoxy-phenyl)-chroman-4-one
1,7-Bis(hydroxymethyl)-9-methoxyphenanthrene-3,6-diol
ACon1_000808
Icariside D2
Icariside D2 is a glycoside. Icariside D2 is a natural product found in Schisandra propinqua, Cyclopia subternata, and other organisms with data available.
LPRP-Et-97543
NCI60_041532
5-Hydroxy-3-(4-hydroxybenzyl)-7-methoxychroman-4-one is a natural product found in Ledebouria leptophylla with data available.
DESMEDIPHAM
CONFIDENCE standard compound; EAWAG_UCHEM_ID 144
8phiC8SPC
C14H20O5S (300.10313900000006)
CONFIDENCE standard compound; EAWAG_UCHEM_ID 3571
4-Hydroxy-5,7-dimethoxyflavanone
relative retention time with respect to 9-anthracene Carboxylic Acid is 1.021 relative retention time with respect to 9-anthracene Carboxylic Acid is 1.022 relative retention time with respect to 9-anthracene Carboxylic Acid is 1.018
Xylure
relative retention time with respect to 9-anthracene Carboxylic Acid is 0.716 relative retention time with respect to 9-anthracene Carboxylic Acid is 0.718 relative retention time with respect to 9-anthracene Carboxylic Acid is 0.712 relative retention time with respect to 9-anthracene Carboxylic Acid is 0.713
7,4-Dimethoxy-5-hydroxyflavanone
4',?7-?Di-?O-?methylnaringenin is a flavonoid found in Renealmia alpinia[1]. 4',?7-?Di-?O-?methylnaringenin is a flavonoid found in Renealmia alpinia[1].
3,9-dihydroxy-1,4,7,10-tetramethylbenzo[b][1,4]benzodioxepin-6-one
5,7-dihydroxy-3-[(4-methoxyphenyl)methyl]-2,3-dihydrochromen-4-one
(E)-1-(3,4-dihydroxy-2,6-dimethoxyphenyl)-3-phenylprop-2-en-1-one
5-hydroxy-7,8-dimethoxy-2-phenyl-2,3-dihydrochromen-4-one
5,7,9-trimethoxy-2-methylbenzo[h]chromen-4-one
4-methoxy-9-(3-methylbut-2-enoxy)furo[3,2-g]chromen-7-one
RAN-dm
C12H20N4O3S (300.12560500000006)
CONFIDENCE Probable structure via diagnostic evidence, tentative identification (Level 2b); ALGAE_TP_ID 3001
8phiC8SPC (STANDARD)
C14H20O5S (300.10313900000006)
Auto-extracted from 131001_neg_02.mzML; CONFIDENCE Reference Standard (Level 1); Kindly provided by Jennifer Field, Oregon State University; Synthesis according to P.W. Taylor and G. Nickless, J. Chromotography, 178 (1979) 259-269.
SPA-8C (SAMPLE)
C14H20O5S (300.10313900000006)
Auto-extracted from 131001_neg_03.mzML; CONFIDENCE Tentative identification: isomers possible (Level 3)
C14H20O7_4-(2-Hydroxyethyl)phenyl beta-D-glucopyranoside
C17H16O5_(3R)-3-(3,4-Dimethoxyphenyl)-8-hydroxy-3,4-dihydro-1H-isochromen-1-one
(3R)-3-(3,4-dimethoxyphenyl)-8-hydroxy-3,4-dihydroisochromen-1-one
(2S,3R,4S,5S,6R)-2-[4-(2-hydroxyethyl)phenoxy]-6-(hydroxymethyl)oxane-3,4,5-triol
(2S,3R,4S,5S,6R)-2-[4-(2-hydroxyethyl)phenoxy]-6-(hydroxymethyl)oxane-3,4,5-triol_major
Promazine sulfoxide
A member of the class of phenothiazines that is promazine carrying an oxo group at position 5. It is a metabolite of the anti-psychotic medication, chlorpromazine.
Homopisatin
2-(3-Hydroxyphenyl)ethanol 1'-glucoside
5,7-Dihydroxy-4'-methoxy-8-methylisoflavanone
5-bromo-1-isopropyl-2,5a-dimethyl-decahydro-cyclopropa[a]inden-2-ol
2-Amino-3-benzoyl-.alpha.-(methylthio)benzeneacetamide
2-(2-CARBOXYMETHYL-PHENOXY)-3,4-DIMETHYL-BENZOIC ACID
4-[(2-methoxy-4-nitrophenyl)azo]-N,N-dimethyl-Benzenamine
C15H16N4O3 (300.12223459999996)
L-Lysine,N6-[(4-methylphenyl)sulfonyl]-
C13H20N2O4S (300.11437200000006)
(4-(2,2-DIPHENYLVINYL)PHENYL)BORONIC ACID
C20H17BO2 (300.13215319999995)
2,4-Pentadien-2-ol,5-(phenylamino)-1-(phenylimino)-, hydrochloride (1:1)
(2S)-4-Oxo-2-(3-thiazolidinylcarbonyl)-1-pyrrolidinecarboxylic acid tert-butyl ester
C13H20N2O4S (300.11437200000006)
2,2,2-TRIFLUORO-1-(3-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENYL)ETHANONE
C14H16BF3O3 (300.11445319999996)
1H-PYRROLO[2,3-B]PYRIDIN-4-OL, 2-(3,4,5-TRIMETHOXYPHENYL)-
2-(1,3-Benzodioxol-5-yl)-1-(5-ethyl-2,4-dihydroxyphenyl)ethanone
2-(2-fluoro-4-methanesulfonylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
C13H18BFO4S (300.10028300000005)
1-PHENYLAMINO-5-PHENYLIMINO-1,3-PENTADIEN-2-OL HYDROCHLORIDE
Butanoic acid,4-chloro-, 2-(diphenylmethylene)hydrazide
Methyl 4-oxo-1-[3-(trifluoromethyl)phenyl]cyclohexanecarboxylate
3-Fluoro-4-(methylsulfonyl)phenylboronic Acid Pinacol Ester
C13H18BFO4S (300.10028300000005)
8-N-BOC-AMINO-1,5-DIHYDRO-[1,2]DIAZEPINO[4,5,6-CD]INDOL-6-ONE
C15H16N4O3 (300.12223459999996)
ETHYL 1-(2,2-DIETHOXYETHYL)-5-NITRO-1H-PYRROLE-2-CARBOXYLATE
2-amino-1-(4-aminophenyl)pyrrolo[3,2-b]quinoxaline-3-carbonitrile
2-[[2-methyl-4-[(4-nitrophenyl)azo]phenyl]amino]ethanol
C15H16N4O3 (300.12223459999996)
(4-fluorophenyl)-[4-(2-phenylethynyl)phenyl]methanone
2-ethoxy-2-[(2-nitrophenyl)amino]-1-phenyl-ethanone
(alphaR)-alpha-Hydroxy-N-[2-(4-nitrophenyl)ethyl]benzeneacetamide
1-(2,4-Difluorophenyl)cyclopropylamine Hydrochloride
5-((Z)-(5-Fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid
C16H13FN2O3 (300.09101599999997)
N-(7-γ-glutamyl)-α-naphthylamide,N-(γ-L-GLUTAMYL)-1-NAPHTHYLAMIDE
4,4,5,5-TETRAMETHYL-2-(4-TRIFLUOROVINYLOXY-PHENYL)-[1,3,2]DIOXABOROLANE
C14H16BF3O3 (300.11445319999996)
3-(4-phenylmethoxyphenyl)-1H-pyrrolo[2,3-b]pyridine
Phenylethylb-D-thiogalactopyranoside
C14H20O5S (300.10313900000006)
5-(tert-butylsulfonyl)-2-morpholinopyrimidin-4-amine
C12H20N4O3S (300.12560500000006)
Benzaldehyde,4-hydroxy-3-methoxy-, 2-[(4-hydroxy-3-methoxyphenyl)methylene]hydrazone
2-(CHLOROMETHYL)-2-METHYL-3-(4-METHYLPHENYL)-1,2,3,4-TETRAHYDROQUINAZOLIN-4-ONE
(R)-tert-butyl 4-oxo-2-(thiazolidine-3-carbonyl)pyrrolidine-1-carboxylate
C13H20N2O4S (300.11437200000006)
1,1-(Methylenedi-4,1-phenylene)bishydrazine Dihydrochloride
2-(4-BUTYLPHENYL)-6-CHLORO-2H-1,2,3-BENZOTRIAZOL-5-AMINE
((Carbonylbis(azanediyl))bis(3,1-phenylene))diboronic acid
3-[(4-fluorophenyl)methyl]-7,7-dimethyl-6,8-dihydrochromene-2,5-dione
(3-CHLORO-PHENYL)-(4-PIPERAZIN-1-YL-PHENYL)-METHANONE
(S)-(+)-2-[4-(Fluorobenzyloxy-Benzylamino)propionamide]
2-(Diethylamino)ethyl 4-amino-5-chloro-2-methoxybenzoate
D018377 - Neurotransmitter Agents > D018490 - Serotonin Agents > D012702 - Serotonin Antagonists
5-Hydroxy-7-methoxy-2-(4-methoxyphenyl)-2,3-dihydrochromen-4-one
N-(2-(3,4-Dichlorophenyl)ethyl)-N-methyl-2-(1-pyrrolidinyl)ethylamine
4H-1-Benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-(2-hydroxyphenyl)-6,8-dimethyl-, (2S)-
N-(5,5-dimethyl-7-oxo-4,6-dihydro-1,3-benzothiazol-2-yl)benzamide
N-[5-(2-chlorophenyl)-1H-1,2,4-triazol-3-yl]-4,6-dimethyl-2-pyrimidinamine
3-(3-Methoxy-4-phenylmethoxyphenyl)-2-oxopropanoic acid
Diethyl (4-hydroxy-2-oxo-4-phenylbutyl)phosphonate
C14H21O5P (300.11265460000004)
rhodosin
Salidroside is a prolyl endopeptidase inhibitor. Salidroside alleviates cachexia symptoms in mouse models of cancer cachexia via activating mTOR signalling. Salidroside protects dopaminergic neurons by enhancing PINK1/Parkin-mediated mitophagy. Salidroside is a prolyl endopeptidase inhibitor. Salidroside alleviates cachexia symptoms in mouse models of cancer cachexia via activating mTOR signalling. Salidroside protects dopaminergic neurons by enhancing PINK1/Parkin-mediated mitophagy.
2-(3-Methoxy-4-methoxyphenyl)-5-hydroxy-2,3-dihydro-4H-1-benzopyran-4-one
4-[1-Methyl-5-(methoxycarbonyl)pentyl]benzenesulfonic acid
C14H20O5S (300.10313900000006)
S-3-hydroxy-4,4-dimethoxydalbergione
A natural product found in Pterocarpus santalinus.
1-[4-Hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-trimethylsilylpyrimidine-2,4-dione
Phenylethyl beta-d-thiogalactoside
C14H20O5S (300.10313900000006)
4-amino-5-[2-amino-3-(1H-imidazol-5-yl)propanoyl]peroxy-5-oxopentanoic acid
4,7-Dihydroxy-N,N,N-trimethyl-4,10-dioxo-3,5,9-trioxa-4lambda~5~-phosphaundecan-1-aminium
C10H23NO7P+ (300.12120780000004)
[5-(4-Nitrophenyl)-2-furanyl]-(1-piperidinyl)methanone
4-[[(4-Methoxyanilino)-oxomethyl]amino]benzoic acid methyl ester
9-(3,5-Difluorophenyl)-6-(ethylamino)-2-purinecarbonitrile
1-(1,3-Benzodioxol-5-ylmethyl)-3-(4-methylphenyl)thiourea
3-(2,3-dihydro-1,4-benzodioxin-3-yl)-N-(3-hydroxy-2-pyridinyl)propanamide
6-Amino-3-tert-butyl-4-thiophen-2-yl-2,4-dihydroisoxazolo[5,4-b]pyridine-5-carbonitrile
Methyl 4-[2-(3-methoxyphenyl)-2-oxoethoxy]benzoate
1-(1,3-Benzodioxol-5-ylmethyl)-3-(2-methylphenyl)thiourea
2-[[2-(3-Methoxyphenoxy)-1-oxoethyl]amino]benzamide
N-(6-butyl-1,3-benzothiazol-2-yl)-2-furancarboxamide
2-(3,4-Diethoxyphenyl)-5-(2-furanyl)-1,3,4-oxadiazole
4-methyl-N-{[(phenylsulfanyl)acetyl]oxy}benzenecarboximidamide
2-Cyano-N-cyclohexyl-3-(4-methylsulfanyl-phenyl)-acrylamide
3-(2-Fluorobenzyl)-5-[(5-methyl-2-furyl)methylene]-2,4-imidazolidinedione
C16H13FN2O3 (300.09101599999997)
(2S,3S)-3,5,7-trihydroxy-6,8-dimethylflavanone
A trihydroxyflavanone that is flavanone substituted by hydroxy groups at positions 3, 5 and 7 and methyl groups at positions 6 and 8 (the 2S,3S-stereoisomer). It has been isolated from the buds of Cleistocalyx operculatus and has been shown to exhibit inhibitory effects on the viral neuraminidases from two influenza viral strains, H1N1 and H9N2.
3,5-Dimethyl-1-[(7-methyl-2-naphthalenyl)sulfonyl]pyrazole
1-Prop-2-enyl-5-[1-(3-pyridinylmethylamino)ethylidene]-1,3-diazinane-2,4,6-trione
C15H16N4O3 (300.12223459999996)
8-hydroxy-7-[(2E)-3-phenylprop-2-en-1-yl]-3,4-dihydro-2H,6H-pyrimido[2,1-b][1,3]thiazin-6-one
1-Carbamoyl-7-(dimethylamino)-3,4-dihydroxyphenoxazin-5-ium
2-[[(2R)-3-acetyloxy-2-hydroxypropoxy]-hydroxyphosphoryl]oxyethyl-trimethylazanium
C10H23NO7P+ (300.12120780000004)
6,6-Dimethyl-9-thiophen-2-yl-5,7,8a,9-tetrahydro-[1,2,4]triazolo[5,1-b]quinazolin-8-one
N-butyl-N(2)-(2-thienylacetyl)-L-cysteinamide
C13H20N2O2S2 (300.09661400000005)
1-(Dimethylamino)-3-(10-phenothiazinyl)-2-propanol
2-[[(2R)-2-acetyloxy-3-hydroxypropoxy]-hydroxyphosphoryl]oxyethyl-trimethylazanium
C10H23NO7P+ (300.12120780000004)
3,9-Dihydroxy-1,4,7,10-tetramethylbenzo[b][1,4]benzodioxepin-6-one
NPPB
D006133 - Growth Substances > D043924 - Angiogenesis Modulating Agents D000970 - Antineoplastic Agents > D020533 - Angiogenesis Inhibitors D006133 - Growth Substances > D006131 - Growth Inhibitors
2-(hydroxymethyl)-6-[2-(4-hydroxyphenyl)ethoxy]oxane-3,4,5-triol
abacavir 5-carboxylic acid
C14H16N6O2 (300.13346759999996)
A monocarboxylic acid oxidation product of abacavir, in which the C-5 hydroxymethyl group has been oxidised to a carboxy group. One of the two major metabolites of abacavir in humans (the other is the 5-glucuronide, CHEBI:64189).
(2S)-5-hydroxy-4,7-dimethoxyflavanone
A 5-hydroxy-4,7-dimethoxyflavanone that has (S)-configuration.
(2S)-2-hydroxydemethoxymatteucinol
A trihydroxyflavanone that is demethoxymatteucinol with an additional hydroxy group at position 2. Isolated from Pisonia aculeata, it exhibits antitubercular activity.
5-hydroxy-4,7-dimethoxyflavanone
A dimethoxyflavanone that is naringenin in which the hydroxy groups at positions 4 and 7 are replaced by methoxy groups.
Nexinhib20
C15H16N4O3 (300.12223459999996)
Nexinhib20 is a specific Rab27a-JFC1 interaction inhibitor with a calculated IC50 of 2.6 μM. Nexinhib20 significantly inhibits superoxide anion production. Nexinhib20 efficiently decreases exocytosis of azurophilic granules in neutrophils stimulated with fMLP, GM-CSF or both. Nexinhib20 has a significant anti-inflammatory activity[1].