Cnidilin (BioDeep_00000000488)

   

PANOMIX_OTCML-2023


代谢物信息卡片


7H-Furo(3,2-g)(1)benzopyran-7-one, 9-methoxy-4-((3-methyl-2-buten-1-yl)oxy)-

化学式: C17H16O5 (300.0997686)
中文名称: 8-甲氧基异欧前胡内酯, 8-氧甲基异欧前胡内酯, 异珊瑚菜素
谱图信息: 最多检出来源 Chinese Herbal Medicine(otcml) 7.69%

分子结构信息

SMILES: CC(=CCOC1=C2C=COC2=C(C3=C1C=CC(=O)O3)OC)C
InChI: InChI=1S/C17H16O5/c1-10(2)6-8-20-14-11-4-5-13(18)22-16(11)17(19-3)15-12(14)7-9-21-15/h4-7,9H,8H2,1-3H3

描述信息

Cnidilin is a member of psoralens.
Cnidilin is a natural product found in Hansenia forbesii, Zanthoxylum americanum, and other organisms with data available.

同义名列表

11 个代谢物同义名

7H-Furo(3,2-g)(1)benzopyran-7-one, 9-methoxy-4-((3-methyl-2-buten-1-yl)oxy)-; 9-Methoxy-4-((3-methylbut-2-en-1-yl)oxy)-7H-furo[3,2-g]chromen-7-one; 9-methoxy-4-(3-methylbut-2-enoxy)furo[3,2-g]chromen-7-one; 5-(Isopentenyloxy)-8-methoxypsoralen; UNII-GGS6U48RG7; Isophellopterin; GGS6U48RG7; kinidilin; Cnidilin; Knidilin; 9-methoxy-4-(3-methylbut-2-enoxy)-7-furo[3,2-g]chromenone



数据库引用编号

13 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

13 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Unwoo Kang, Ah-Reum Han, Yangkang So, Chang Hyun Jin, Seung Mok Ryu, Dongho Lee, Eun Kyoung Seo. Furanocoumarins from the Roots of Angelica dahurica with Inhibitory Activity against Intracellular Reactive Oxygen Species Accumulation. Journal of natural products. 2019 09; 82(9):2601-2607. doi: 10.1021/acs.jnatprod.9b00547. [PMID: 31464439]
  • Lin Yuan, Yuqian Zhang, Man Liao, Yanyan Liu, Changchen Wan, Lantong Zhang. UHPLC-Q-TOF-MS/MS-based screening and characterization of metabolites of cnidilin in human liver microsomes. Biomedical chromatography : BMC. 2017 Nov; 31(11):. doi: 10.1002/bmc.3992. [PMID: 28431455]
  • Jinmei Wang, Linna Peng, Mengjun Shi, Changqin Li, Yan Zhang, Wenyi Kang. Spectrum Effect Relationship and Component Knock-Out in Angelica Dahurica Radix by High Performance Liquid Chromatography-Q Exactive Hybrid Quadrupole-Orbitrap Mass Spectrometer. Molecules (Basel, Switzerland). 2017 Jul; 22(7):. doi: 10.3390/molecules22071231. [PMID: 28754032]
  • Haoli Huo, Peipei Jia, Xiaoxu Zhang, Zhiyong Zhang, Haotian Yang, Qiaoyue Zhang, He Shi, Lantong Zhang. Tentative identification of new metabolites of cnidilin by liquid chromatography-mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2015 Jul; 995-996(?):85-92. doi: 10.1016/j.jchromb.2015.05.002. [PMID: 26038237]
  • Hong Zhu, Yanping Ren, Yingguang Sun, Lu Chang, Liang Cao, Huijin Xu, Lantong Zhang. Determination of cnidilin and its two metabolites in rat bile and stool after oral administration by HPLC/electrospray ionization tandem mass spectrometry. Biomedical chromatography : BMC. 2013 Apr; 27(4):527-34. doi: 10.1002/bmc.2827. [PMID: 23019010]
  • Wan Lili, Sun Yehong, Yu Qi, Huo Yan, Zhu Jinhui, Li Yan, Guo Cheng. In vitro permeability analysis, pharmacokinetic and brain distribution study in mice of imperatorin, isoimperatorin and cnidilin in Radix Angelicae Dahuricae. Fitoterapia. 2013 Mar; 85(?):144-53. doi: 10.1016/j.fitote.2013.01.007. [PMID: 23353658]
  • Hong Zhu, Pengwei Liu, Xiaowei Shi, Huijun Xu, Yanping Ren, Qiao Wang, Lantong Zhang. Determination of cnidilin and its two metabolites in rat plasma by high-performance liquid chromatography-electrospray ionization tandem mass spectrometry. Planta medica. 2013 Jan; 79(1):30-6. doi: 10.1055/s-0032-1327983. [PMID: 23188706]
  • Janine Zaugg, Eva Eickmeier, Diana C Rueda, Steffen Hering, Matthias Hamburger. HPLC-based activity profiling of Angelica pubescens roots for new positive GABAA receptor modulators in Xenopus oocytes. Fitoterapia. 2011 Apr; 82(3):434-40. doi: 10.1016/j.fitote.2010.12.001. [PMID: 21147202]