Exact Mass: 265.0618
Exact Mass Matches: 265.0618
Found 422 metabolites which its exact mass value is equals to given mass value 265.0618,
within given mass tolerance error 0.05 dalton. Try search metabolite list with more accurate mass tolerance error
0.01 dalton.
Albendazole
Albendazole is only found in individuals that have used or taken this drug. It is a benzimidazole broad-spectrum anthelmintic structurally related to mebendazole that is effective against many diseases. (From Martindale, The Extra Pharmacopoeia, 30th ed, p38)Albendazole causes degenerative alterations in the tegument and intestinal cells of the worm by binding to the colchicine-sensitive site of tubulin, thus inhibiting its polymerization or assembly into microtubules. The loss of the cytoplasmic microtubules leads to impaired uptake of glucose by the larval and adult stages of the susceptible parasites, and depletes their glycogen stores. Degenerative changes in the endoplasmic reticulum, the mitochondria of the germinal layer, and the subsequent release of lysosomes result in decreased production of adenosine triphosphate (ATP), which is the energy required for the survival of the helminth. Due to diminished energy production, the parasite is immobilized and eventually dies. P - Antiparasitic products, insecticides and repellents > P02 - Anthelmintics > P02C - Antinematodal agents > P02CA - Benzimidazole derivatives D000890 - Anti-Infective Agents > D000977 - Antiparasitic Agents > D000981 - Antiprotozoal Agents D050258 - Mitosis Modulators > D050256 - Antimitotic Agents > D050257 - Tubulin Modulators D000890 - Anti-Infective Agents > D000977 - Antiparasitic Agents > D000871 - Anthelmintics C254 - Anti-Infective Agent > C276 - Antiparasitic Agent > C250 - Antihelminthic Agent D000970 - Antineoplastic Agents > D050256 - Antimitotic Agents CONFIDENCE standard compound; EAWAG_UCHEM_ID 3580 KEIO_ID A082; [MS3] KO008867 KEIO_ID A082; [MS2] KO008866 KEIO_ID A082 Albendazole (SKF-62979) is an orally active and broad-spectrum parasiticide with high effectiveness and low host toxicity, is used for the research of gastrointestinal parasites in humans and animals. Albendazole induces apoptosis and autophagy in cancer cells. Albendazole also inhibits tubulin polymerization and HIF-1α, VEGF expression, has antioxidant activity, and inhibits the glycolytic process in cancer cells[1][2][3][4][5].
Anonaine
Alkaloid from Annona muricata (soursop) and Nelumbo nucifera (East India lotus). Anonaine is found in many foods, some of which are sugar apple, sacred lotus, fruits, and custard apple. Anonaine is found in cherimoya. Anonaine is an alkaloid from Annona muricata (soursop) and Nelumbo nucifera (East India lotus
Streptozocin
Streptozocin is only found in individuals that have used or taken this drug.It is an antibiotic that is produced by Stretomyces achromogenes. It is used as an antineoplastic agent and to induce diabetes in experimental animals. [PubChem]Although its mechanism of action is not completely clear, streptozocin is known to inhibit DNA synthesis, interfere with biochemical reactions of NAD and NADH, and inhibit some enzymes involved in gluconeogenesis. Its activity appears to occur as a result of formation of methylcarbonium ions, which alkylate or bind with many intracellular molecular structures including nucleic acids. Its cytotoxic action is probably due to cross-linking of strands of DNA, resulting in inhibition of DNA synthesis. L - Antineoplastic and immunomodulating agents > L01 - Antineoplastic agents > L01A - Alkylating agents > L01AD - Nitrosoureas D000970 - Antineoplastic Agents
Furofoline
Furofoline is found in herbs and spices. Furofoline is an alkaloid from the roots of Ruta graveolens (rue Alkaloid from the roots of Ruta graveolens (rue). Furofoline is found in herbs and spices.
2,3-Di(4-methoxyphenyl)acrylonitrile
Isoniazid alpha-ketoglutaric acid
Isoniazid alpha-ketoglutaric acid is a metabolite of isoniazid. Isoniazid (Laniazid, Nydrazid), also known as isonicotinylhydrazine (INH), is an organic compound that is the first-line medication in prevention and treatment of tuberculosis. (Wikipedia)
Piperolactam A
Piperolactam A is an alkaloid. Piperolactam A is a natural product found in Piper auritum, Aristolochia cucurbitifolia, and other organisms with data available. Piperolactam A is an alkaloid from roots of Piper longum (long pepper). Alkaloid from roots of Piper longum (long pepper).
Agaritinal
Agaritinal is found in mushrooms. Agaritinal is isolated from Agaricus campestris (field mushroom). Isolated from Agaricus campestris (field mushroom). Agaritinal is found in mushrooms.
Desacetyl-nitazoxanide
Desacetyl-nitazoxanide is a metabolite of lamivudine. Lamivudine (2,3-dideoxy-3-thiacytidine, commonly called 3TC) is a potent nucleoside analog reverse transcriptase inhibitor (nRTI). It is marketed by GlaxoSmithKline with the brand names Zeffix, Heptovir, Epivir, and Epivir-HBV. Lamivudine has been used for treatment of chronic hepatitis B at a lower dose than for treatment of HIV. It improves the seroconversion of e-antigen positive hepatitis B and also improves histology staging of the liver. (Wikipedia) D000890 - Anti-Infective Agents
Nitecapone
Nitecapone belongs to the family of Nitrophenols and Derivatives. These are compounds containing a nitrophenol moiety, which consists of a benzene ring bearing both an hydroxyl group and a nitro group on two different ring carbon atoms. D002491 - Central Nervous System Agents > D018726 - Anti-Dyskinesia Agents > D000978 - Antiparkinson Agents D004791 - Enzyme Inhibitors > D065098 - Catechol O-Methyltransferase Inhibitors C78272 - Agent Affecting Nervous System > C38149 - Antiparkinsonian Agent D005765 - Gastrointestinal Agents > D000897 - Anti-Ulcer Agents D020011 - Protective Agents > D000975 - Antioxidants C471 - Enzyme Inhibitor
2-(2-Phenylacetoxy)propionylglycine
2-(2-Phenylacetoxy)propionylglycine belongs to the family of N-acyl-alpha Amino Acids and Derivatives. These are compounds containing an alpha amino acid which bears an acyl group at his terminal nitrogen atom.
Phenylacetylglutamate
N-Phenylacetylglutamic acid belongs to the family of N-acyl-alpha Amino Acids and Derivatives. These are compounds containing an alpha amino acid which bears an acyl group at his terminal nitrogen atom.
(2-Carbamoyl-7-oxo-1,6-diazabicyclo[3.2.1]octan-6-yl) hydrogen sulfate
Dansyl hydrazine
D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents > D049408 - Luminescent Agents D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents > D003619 - Dansyl Compounds D004396 - Coloring Agents > D005456 - Fluorescent Dyes
N-(2-(Methylamino)ethyl)-5-isoquinolinesulfonamide
D004791 - Enzyme Inhibitors > D047428 - Protein Kinase Inhibitors
Adenosine dialdehyde
Adenosine dialdehyde, a purine nucleoside analogue, is a potent inhibitor of S-Adenosylhomocysteine hydrolase (SAHH) (Ki=3.3 nM)[1]. Adenosine Dialdehyde exhibits potent anti-tumor activity in vivo and can be used for the cancer research[1][2].
D-Glucose, 2-deoxy-2-[[(methylnitrosoamino)carbonyl]amino]-
D000970 - Antineoplastic Agents
7H-Pyrrolo(3,2,1-de)phenanthridin-7-one, 10-hydroxy-9-methoxy-
Dansyl hydrazine
D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents > D049408 - Luminescent Agents D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents > D003619 - Dansyl Compounds D004396 - Coloring Agents > D005456 - Fluorescent Dyes
N-(2-Chlorophenyl)-N-(2-cyanoethyl)-N-isopropylurea
2-amino-3,4,5,6-tetrahydro-4,6-dioxo-7-pteridinepyruvic acid
(Z)-2-phenylethenylamide-2,3-Epoxy-6,8-nonadiynoic acid|2,3-Epoxy-6,8-nonadiynoic acid cinnamylamide
Benzenesulfonamide, 4-amino-N-(5-hydroxy-2-pyridinyl)-
Piperolactam A
2-Hydroxysaclofen
D018377 - Neurotransmitter Agents > D018682 - GABA Agents > D018756 - GABA Antagonists
AristolactamAII
Aristolactam AII is a natural product found in Marsypopetalum crassum, Dasymaschalon rostratum, and other organisms with data available.
albendazole
P - Antiparasitic products, insecticides and repellents > P02 - Anthelmintics > P02C - Antinematodal agents > P02CA - Benzimidazole derivatives D000890 - Anti-Infective Agents > D000977 - Antiparasitic Agents > D000981 - Antiprotozoal Agents D050258 - Mitosis Modulators > D050256 - Antimitotic Agents > D050257 - Tubulin Modulators D000890 - Anti-Infective Agents > D000977 - Antiparasitic Agents > D000871 - Anthelmintics C254 - Anti-Infective Agent > C276 - Antiparasitic Agent > C250 - Antihelminthic Agent D000970 - Antineoplastic Agents > D050256 - Antimitotic Agents CONFIDENCE standard compound; INTERNAL_ID 453; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4179; ORIGINAL_PRECURSOR_SCAN_NO 4175 CONFIDENCE standard compound; INTERNAL_ID 453; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4196; ORIGINAL_PRECURSOR_SCAN_NO 4193 CONFIDENCE standard compound; INTERNAL_ID 453; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4155; ORIGINAL_PRECURSOR_SCAN_NO 4150 CONFIDENCE standard compound; INTERNAL_ID 453; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4179; ORIGINAL_PRECURSOR_SCAN_NO 4176 CONFIDENCE standard compound; INTERNAL_ID 453; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4182; ORIGINAL_PRECURSOR_SCAN_NO 4180 CONFIDENCE standard compound; INTERNAL_ID 453; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4169; ORIGINAL_PRECURSOR_SCAN_NO 4165 CONFIDENCE standard compound; INTERNAL_ID 453; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8331; ORIGINAL_PRECURSOR_SCAN_NO 8330 CONFIDENCE standard compound; INTERNAL_ID 453; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8365; ORIGINAL_PRECURSOR_SCAN_NO 8363 CONFIDENCE standard compound; INTERNAL_ID 453; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8375; ORIGINAL_PRECURSOR_SCAN_NO 8373 CONFIDENCE standard compound; INTERNAL_ID 453; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8413; ORIGINAL_PRECURSOR_SCAN_NO 8412 CONFIDENCE standard compound; INTERNAL_ID 453; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8422; ORIGINAL_PRECURSOR_SCAN_NO 8420 CONFIDENCE standard compound; INTERNAL_ID 453; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8421; ORIGINAL_PRECURSOR_SCAN_NO 8419 CONFIDENCE standard compound; INTERNAL_ID 1058 CONFIDENCE standard compound; INTERNAL_ID 8535 Albendazole (SKF-62979) is an orally active and broad-spectrum parasiticide with high effectiveness and low host toxicity, is used for the research of gastrointestinal parasites in humans and animals. Albendazole induces apoptosis and autophagy in cancer cells. Albendazole also inhibits tubulin polymerization and HIF-1α, VEGF expression, has antioxidant activity, and inhibits the glycolytic process in cancer cells[1][2][3][4][5].
1-Hydroxy-2-methoxydibenzo[cd,f]indol-4(5H)-one
PharmaGSID_47261
CONFIDENCE standard compound; INTERNAL_ID 853; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4350; ORIGINAL_PRECURSOR_SCAN_NO 4349 CONFIDENCE standard compound; INTERNAL_ID 853; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4367; ORIGINAL_PRECURSOR_SCAN_NO 4366 CONFIDENCE standard compound; INTERNAL_ID 853; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4346; ORIGINAL_PRECURSOR_SCAN_NO 4345 CONFIDENCE standard compound; INTERNAL_ID 853; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4372; ORIGINAL_PRECURSOR_SCAN_NO 4370 CONFIDENCE standard compound; INTERNAL_ID 853; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4388; ORIGINAL_PRECURSOR_SCAN_NO 4386 CONFIDENCE standard compound; INTERNAL_ID 853; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4386; ORIGINAL_PRECURSOR_SCAN_NO 4384 CONFIDENCE standard compound; INTERNAL_ID 853; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8624; ORIGINAL_PRECURSOR_SCAN_NO 8621 CONFIDENCE standard compound; INTERNAL_ID 853; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8706; ORIGINAL_PRECURSOR_SCAN_NO 8704 CONFIDENCE standard compound; INTERNAL_ID 853; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8736; ORIGINAL_PRECURSOR_SCAN_NO 8734 CONFIDENCE standard compound; INTERNAL_ID 853; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8745; ORIGINAL_PRECURSOR_SCAN_NO 8743 CONFIDENCE standard compound; INTERNAL_ID 853; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8768; ORIGINAL_PRECURSOR_SCAN_NO 8766 CONFIDENCE standard compound; INTERNAL_ID 853; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8748; ORIGINAL_PRECURSOR_SCAN_NO 8744
2-OH-Saclofen
D018377 - Neurotransmitter Agents > D018682 - GABA Agents > D018756 - GABA Antagonists
Oxinofen
M - Musculo-skeletal system > M01 - Antiinflammatory and antirheumatic products > M01C - Specific antirheumatic agents > M01CA - Quinolines C78272 - Agent Affecting Nervous System > C241 - Analgesic Agent > C2198 - Nonnarcotic Analgesic C26170 - Protective Agent > C921 - Uricosuric Agent
Nitecapone
D002491 - Central Nervous System Agents > D018726 - Anti-Dyskinesia Agents > D000978 - Antiparkinson Agents D004791 - Enzyme Inhibitors > D065098 - Catechol O-Methyltransferase Inhibitors C78272 - Agent Affecting Nervous System > C38149 - Antiparkinsonian Agent D005765 - Gastrointestinal Agents > D000897 - Anti-Ulcer Agents D020011 - Protective Agents > D000975 - Antioxidants C471 - Enzyme Inhibitor
4-(4-METHANESULFONYL-BENZYLIDENE)-2-METHYL-4H-OXAZOL-5-ONE
1-CYCLOPROPYL-6,7-DIFLUORO-1,4-DIHYDRO-4-OXOQUINOLINE-3-CARBOXYLIC ACID
4-ethyl-3-[(4-methoxyphenoxy)methyl]-1H-1,2,4-triazole-5-thione
ethyl 3-methyl-5-nitro-benzothiophene-2-carboxylate
[2-(3,4-DIHYDRO-2H-QUINOLIN-1-YL)-2-OXO-ETHYLSULFANYL]-ACETIC ACID
tert-butyl 3-[(methanesulfonyloxy)methyl]azetidine-1-carboxylate
3-amino-2-hydroxy-[1,1-biphenyl]-3-carboxylic acid hydrochloride
2-(1,3-dioxoisoindol-2-yl)-3-methylsulfanylpropanoic acid
4-(4-Methylphenylsulfonyl)semicarbazide hydrochloride
6-chloro-4-morpholin-4-ylpyrido[3,2-d]pyrimidin-2-amine
(2E)-2-[(2-nitrophenyl)methylidene]-3H-inden-1-one
1-(3,4-Difluorobenzyl)-2-oxo-1,2-dihydropyridine-3-carboxylic acid
(2-amino-4,5-dimethylthiophen-3-yl)(4-chlorophenyl)methanone
ETHYL 3-AMINO-1-(4-CHLOROPHENYL)-1H-PYRAZOLE-4-CARBOXYLATE
1-propoxyisoquinoline-3-carboximidamide,hydrochloride
3-AMINO-3-[5-(2-CHLOROPHENYL)-FURAN-2-YL]-PROPIONIC ACID
3-AMINO-3-[5-(3-CHLOROPHENYL)-FURAN-2-YL]-PROPIONIC ACID
4-(2,6-difluoro-4-methylbenzoyl)-1H-pyrrole-2-carboxylic acid
3-hydroxy-1-methyl-2-(4-methylphenyl)quinolin-4-one
1,3-dimethyl-5-[2-(3-methyl-1,3-oxazolidin-2-ylidene)ethylidene]-1,3-diazinane-2,4,6-trione
4-(4-TRIFLUOROMETHYLPHENYL)PIPERIDINEHYDROCHLORIDE
4-(3-trifluoromethylphenyl)piperidine hydrochloride
ETHYL 2-AMINO-4-(4-FLUOROPHENYL)THIOPHENE-3-CARBOXYLATE
(s)-3-amino-4-(1-naphthyl)butanoic acid hydrochloride
ethyl 6-methyl-5-nitro-1-benzothiophene-2-carboxylate
{[4-(4-METHOXYPHENYL)-4H-1,2,4-TRIAZOL-3-YL]THIO}ACETIC ACID
4-FLUORO-3-(TRIFLUOROMETHYL)-[1,1-BIPHENYL]-2-CARBONITRILE
4-FLUORO-3-(TRIFLUOROMETHYL)-[1,1-BIPHENYL]-3-CARBONITRILE
Ethyl 1-(3-chloropyridin-2-yl)-5-methyl-1H-pyrazole-4-carboxylate
Ethyl 1-(6-chloropyridin-2-yl)-5-methyl-1H-pyrazole-4-carboxylate
4-HYDROXYMETHYL-3-(4-NITRO-BENZYL)-2-MERCAPTO-3H-IMIDAZOLE
1-BUTYL-3-CHLORO-3-METHYL-1,2,3,4-TETRAHYDROQUINOLINE-2,4-DIONE
Avibactam
A member of the class of azabicycloalkanes that is (2S,5R)-7-oxo-1,6-diazabicyclo[3.2.1]octane-2-carboxamide in which the amino hydrogen at position 6 is replaced by a sulfooxy group. Used (in the form of its sodium salt) in combination with ceftazidime pentahydrate for the treatment of complicated urinary tract infections including pyelonephritis. D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D065093 - beta-Lactamase Inhibitors D004791 - Enzyme Inhibitors
Dipraglurant
C78272 - Agent Affecting Nervous System Dipraglurant (ADX48621) is a potent, selective, orally active and brain penetrant mGluR5 negative allosteric modulator (NAM), with an IC50 of 21 nM. Dipraglurant can reduce Levodopa-induced dyskinesia (LID) in vivo[1][2]. Dipraglurant is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
methyl 6-chloro-2-(4-fluorophenyl)pyridine-3-carboxylate
1-[3-chloro-5-(trifluoromethyl)pyrid-2-yl]piperazine
4-(2,2-DIMETHOXYETHYL)-5-PHENYL-4H-1,2,4-TRIAZOLE-3-THIOL
(4-cyano-3,5-difluorophenyl) cyclohexanecarboxylate
ETHYL5-AMINO-1-(4-CHLOROPHENYL)-1H-PYRAZOLE-4-CARBOXYLATE
(R)-3-Methanesulfonyloxy-pyrrolidine-1-carboxylic acid tert-butyl ester
(2-(ISOPROPYLTHIO)-5-(TRIFLUOROMETHYL)PYRIDIN-3-YL)BORONIC ACID
2,6-Difluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile
5-(2-Methyl-4-nitrophenyl)furan-2-carbonyl chloride
4-(2-HYDROXYANILINO)-1,2-DIHYDRONAPHTHALENE-1,2-DIONE
3-(2-oxo-2-pyridin-4-ylethylidene)-1,4-dihydroquinoxalin-2-one
(2-AMINO-5-ETHYLTHIOPHEN-3-YL)(2-CHLOROPHENYL)METHANONE
METHYL 3-(2-CHLOROPHENYL)-5-FORMYLISOXAZOLE-4-CARBOXYLATE
METHYL 3-(4-CHLOROPHENYL)-5-FORMYLISOXAZOLE-4-CARBOXYLATE
3-(PIPERIDIN-4-YL)-2H-BENZO[E][1,2,4]THIADIAZINE 1,1-DIOXIDE
3-[N,N-Bis(hydroxyethyl)amino]-2-hydroxypropanesulphonic acid sodium salt
2-CHLORO-1-[1-(4-FLUOROPHENYL)-2,5-DIMETHYL-1H-PYRROL-3-YL]-1-ETHANONE
5-AMINO-1-(2-CHLORO-PHENYL)-1H-PYRAZOLE-4-CARBOXYLICACIDETHYLESTER
2-Methyl-10H-benzo[b]thieno[2,3-e][1,4]diazepin-4-amine hydrochloride
5-(Piperidin-3-yl)-3-(pyridin-3-yl)-1,2,4-oxadiazole hydrochloride
9-BROMO-2,3,4,5-TETRAHYDRO-1H-BENZO[4,5]IMIDAZO[1,2-D][1,4]DIAZEPINE
5-AMINO-1-(2-CHLORO-PHENYL)-1H-PYRAZOLE-3-CARBOXYLICACIDETHYLESTER
4-(5-phenyl-1,3,4-oxadiazol-2-yl)piperidine hydrochloride
3-chloro-4-(1,4-dioxaspiro[4.5]dec-7-en-8-yl)aniline
(R)-5-chloro-2-(5-Methyl-1,4-diazepan-1-yl)benzo[d]oxazole
3-phenyl-5-piperidin-4-yl-1,2,4-oxadiazole,hydrochloride
Pyridoxal phosphate hydrate
D018977 - Micronutrients > D014815 - Vitamins Pyridoxal 5'-phosphate hydrate, the active form of vitamin B6, is an essential cofactor for multiple enzymes, including aromatic l-amino acid decarboxylase that catalyzes the final stage in the production of the neurotransmitters dopamine and serotonin. Pyridoxal 5'-phosphate hydrate is the most important coenzyme variant in the process of vitamin B6 intracellular phosphorylation and is interconvertible with other variants, including pyridoxine 5′‐phosphate (PNP) and pyridoxamine 5′‐phosphate (PMP)[1][2].
4-ALLYL-5-[(4-FLUOROPHENOXY)METHYL]-4H-1,2,4-TRIAZOLE-3-THIOL
3-(3,4-dimethoxyphenyl)-4-ethyl-1H-1,2,4-triazole-5-thione
8-BROMO-2,3,4,5-TETRAHYDRO-1H-BENZO[4,5]IMIDAZO[1,2-D][1,4]DIAZEPINE
Ethyl 3-amino-3-(3,5-difluorophenyl)propionate hydrochloride
2-AMINO-4-(4-FLUOROPHENYL)-5-METHYLTHIOPHENE-3-CARBOXYLICACIDMETHYLESTER
methyl 3-amino-4-cyano-5-piperidin-1-ylthiophene-2-carboxylate
2-(1,3-Benzodioxol-5-yl)indolizine-3-carboxaldehyde
2-AMINO-8-PYRIDIN-3-YL-7,9-DIOXA-1-THIA-3-AZA-SPIRO[4.5]DEC-2-EN-4-ONE
8-AMINO-4-0X0-2-[1H -TETRAZOLE-5YL ) 4H-1-BENZOPYRAN HYDROCHLORIDE
ETHYL5-AMINO-1-(3-CHLOROPHENYL)-1H-PYRAZOLE-4-CARBOXYLATE
5-PHENYL-3-(PIPERIDIN-3-YL)-1,2,4-OXADIAZOLE HYDROCHLORIDE
2,4(1H,3H)-Pyrimidinedione,5-[bis(2-chloroethyl)amino]-6-methyl-
2-OXO-6-PYRIDIN-3-YL-4-(TRIFLUOROMETHYL)-1,2-DIHYDROPYRIDINE-3-CARBONITRILE
2-AMINO-7-ETHYL-5-OXO-5H-(1)BENZOPYRANO-(2,3-B)PYRIDINE-3-CARBONITRILE
4-(2-(TRIFLUOROMETHYL)PHENYL)PIPERIDINE HYDROCHLORIDE
ETHYL 5-CYANO-3,4-DIMETHYLTHIENO[2,3-B]THIOPHENE-2-CARBOXYLATE
ETHYL 4-(CHLOROSULFONYL)-3,5-DIMETHYL-1H-PYRROLE-2-CARBOXYLATE
5-nitro-2-piperazin-1-yl-benzoic acid methyl ester
1-(4-chlorophenyl)- 1,3,8-triazaspiro[4.5]decan-4-one
1-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]piperidine-4-carbaldehyde
Acetamide,N-[5-[(phenylmethyl)thio]-1,3,4-thiadiazol-2-yl]-
N-(5-acetyl-3-fluoro-6-oxocyclohexa-2,4-dien-1-ylidene)-2,3-dihydro-1H-tetrazole-5-carboxamide
4,6-diamino-2-oxo-1-phenyl-3H-pyrrolo[2,3-b]pyridine-5-carbonitrile
1-[(3-amino-2-chloroquinolin-4-yl)amino]-2-methylpropan-2-ol
2-Chloromethyl-3-Methyl-4-(3-Methoxypropoxy)Pyridine Hydrochloride
(s)-3-amino-4-(2-naphthyl)butanoic acid hydrochloride
1-PHENYL-3-PYRIDIN-3-YL-1H-PYRAZOLE-4-CARBOXYLIC ACID
4-Thiazolidinone,5-[(2-ethoxyphenyl)methylene]-2-thioxo-
3-Quinolinecarboxylicacid, 7-chloro-4-hydroxy-8-methyl-, ethyl ester
(r)-3-amino-4-(1-naphthyl)butanoic acid hydrochloride
(r)-3-amino-4-(2-naphthyl)butanoic acid hydrochloride
5-Chloro-2-(hexahydro-5-methyl-1H-1,4-diazepin-1-yl)benzoxazole
5-CHLORO-4-(4-METHYL-3-NITROPHENYL)PYRIDAZIN-3(2H)-ONE
4-(ISOPROPYLTHIO)-1,3-DIMETHYL-1H-PYRAZOLO[3,4-B]PYRIDINE-5-CARBOXYLIC ACID
1-[2-(4-chlorophenoxy)-5-fluorophenyl]-N-methylmethanamine
2-PYRIDIN-4-YL-1-(4-TRIFLUOROMETHYL-PHENYL)-ETHANONE
2-(Pyrimidin-2-ylaminomethylene)-malonic acid diethyl ester
Ethyl 5-chloro-8-methyl-4-oxo-1,4-dihydroquinoline-3-carboxylate
NSC59984
NSC59984 induces mutant p53 protein degradation via MDM2 and the ubiquitin-proteasome pathway[1]. NSC59984 acts by targeting GOF-mutant p53 and stimulates p73 to restore the p53 pathway signaling[2].
((1S,4R)-4-(2-amino-6-chloro-9H-purin-9-yl)cyclopent-2-enyl)methanol
2-chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid
(2S,5R)-2-carbamoyl-7-oxo-1,6-diazabicyclo[3.2.1]octan-6-yl sulfate
Org 12962
Org-12962 is a potent, selective and orally active 5-HT2C?receptor agonist with a pEC50?value of 7.01. Org-12962 also exhibits high effacy for the 5-HT2A?and 5-HT2B receptor with pEC50s of 6.38 and 6.28, respectively[1][3].Org-12962 displays antiaversive effects in a rat model of panic-like anxiety[2].
N-(2-ACRYLOYLOXYETHYL)-N,N-DIMETHYL-N-(3-SULFOPROPYL)AMMONIUM BETAINE
Methanone,[2-(1-methylethyl)-3-benzofuranyl]-4-pyridinyl-
2-fluoro-5-[(Z)-(3-oxo-2-benzofuran-1-ylidene)methyl]benzonitrile
3-(ETHYLTHIO)-6,6-DIMETHYL-4-OXO-4,5,6,7-TETRAHYDROBENZO[C]THIOPHENE-1-CARBONITRILE
1H-Isoindole-1,3(2H)-dione,2-(2-oxo-2-phenylethyl)-
4-Hydrazino-N-metyl benzene ethane sulfonamide hydrochloride
5,5,5-trifluoro-N-(4-fluorophenyl)-4-hydroxypentanamide
6-chloro-4-hydroxy-8-methylquinoline-3-carboxylic ethyl ester
1-[4-(5-Fluoro-2-hydroxybenzoyl)-1-piperidinyl]-ethanone
1,4,5,6-TETRAHYDRO-2-METHYL-6-OXO-4-(4-CHLOROPHENYL)-3-PYRIDINECARBOXYLIC ACID
4-ISOXAZOLECARBOXYLIC ACID, 3-(4-CHLOROPHENYL)-5-METHYL-, ETHYL ESTER
N-(2-Chloroethyl)-N-(2,6-dihydroxycyclohexyl)-N-nitrosourea
4-[(6-Amino-4-pyrimidinyl)amino]benzenesulfonamide
[5-Hydroxy-2-(4-hydroxyphenyl)-1-benzofuran-7-YL]acetonitrile
5,6,7-Trimethoxy-1-methyl-1H-indole-2-carboxylic acid
(2E)-3-(3-phenylbenzo[c]isoxazol-5-yl)prop-2-enoic acid
N-[5-(2-methoxyphenyl)-1,3,4-thiadiazol-2-yl]carbamic acid methyl ester
5-(2,2-dimethoxyethyl)-4-phenyl-4H-1,2,4-triazole-3-thiol
8,5-Cyclo-2-deoxyguanosine
An organic heterotetracyclic compound obtained by intramolecular formation of a C-C bond between positions 8 and 5 of 2-deoxyguanosine.
1-[4-(4-Chlorophenyl)thiazol-2-yl]-2-(propan-2-ylidene)hydrazine
2-chloro-N-(4,7-dimethyl-2-oxo-1-benzopyran-6-yl)acetamide
2-(3-Benzyl-2,4-dioxo-1,3-thiazolidin-5-yl)acetic acid
1-(3,4-Dihydroxyphenyl)-2-[(4-methyl-1,2,4-triazol-3-yl)thio]ethanone
(2S,3S)-3-methyl-2-(3-oxo-1,2-benzothiazol-2-yl)pentanoic acid
(1E,2E)-N-[(Pentafluorophenyl)methoxy]but-2-en-1-imine
3-Fluoro-4-Hydroxybenzaldehyde O-(Cyclohexylcarbonyl)oxime
(1-Oxyl-2,2,5,5-tetramethyl-3-pyrroline-3-methyl) Methanethiosulfonate-15N,d15
2-Amino-3-(Cystein-S-Yl)-Isoxazolidin-5-Yl-Acetic Acid
Oxycinchophen
M - Musculo-skeletal system > M01 - Antiinflammatory and antirheumatic products > M01C - Specific antirheumatic agents > M01CA - Quinolines C78272 - Agent Affecting Nervous System > C241 - Analgesic Agent > C2198 - Nonnarcotic Analgesic C26170 - Protective Agent > C921 - Uricosuric Agent
Nigerloxin
A member of the class of benzoic acids that is benzoic acid which is substituted at positions 2, 3, 4, 5, and 6 by carbamoyl, hydroxy, E)-prop-1-en-1-yl, methyl, and methoxy groups, respectively. Obtained from solid-state fermentation of Aspergillus niger CFR-W-105, it inhibits soy bean lipoxygenase-1 (LOX-1) and rat lens aldose reductase (RLAR). It also shows free radical scavenging activity.
Amiloride hydrochloride
D049990 - Membrane Transport Modulators > D026941 - Sodium Channel Blockers > D062686 - Epithelial Sodium Channel Blockers D049990 - Membrane Transport Modulators > D026941 - Sodium Channel Blockers > D062646 - Acid Sensing Ion Channel Blockers D002317 - Cardiovascular Agents > D026941 - Sodium Channel Blockers D002317 - Cardiovascular Agents > D045283 - Natriuretic Agents D045283 - Natriuretic Agents > D004232 - Diuretics
tert-butyl N-[(E)-(3-nitrophenyl)methylideneamino]carbamate
6-Methoxy-2-pyridin-4-ylmethylene-3,4-dihydro-2H-naphthalen-1-one
N,N-diethyl-5-thiophen-2-yl-2-thiophenecarboxamide
(5E)-5-[(2-hydroxy-3-nitrophenyl)methylidene]-2-sulfanylideneimidazolidin-4-one
N-[3-(methylthio)-1,2,4-thiadiazol-5-yl]-2-phenylacetamide
6-chloro-2-[(1H-1,2,4-triazol-5-ylthio)methyl]imidazo[1,2-a]pyridine
N-(5-methyl-4,5-dihydrothiazol-2-yl)-3-nitrobenzamide
4-(3,4-dihydro-2H-1,5-benzodioxepin-7-ylamino)-4-oxobutanoic acid
Sulfapyridine hydroxylamine
A pyridine having a 4-hydroxyaminobenzenesulfonamido group at the 2-position.
5-Tert-butyl-3-[(2-cyanoacetyl)amino]thiophene-2-carboxamide
5-butyl-2-[(2E)-2-(furan-2-ylmethylidene)hydrazinyl]-1,3-thiazol-4-one
4H-Pyrido[1,2-a]pyrimidine-3-carboxylic acid, 6,7,8,9-tetrahydro-9-(hydroxyimino)-6-methyl-4-oxo-, ethyl ester
Streptozocin
An N-nitrosourea that is an antibiotic produced by Streptomyces achromogenes. It is used as an antineoplastic agent and to induce diabetes in experimental animals. L - Antineoplastic and immunomodulating agents > L01 - Antineoplastic agents > L01A - Alkylating agents > L01AD - Nitrosoureas D000970 - Antineoplastic Agents
N-(2-(METHYLAMINO)ETHYL)ISOQUINOLINE-
D004791 - Enzyme Inhibitors > D047428 - Protein Kinase Inhibitors
3-(4-hydroxy-2-imino-6-oxo-1,5-dihydropteridin-7-yl)-2-oxopropanoic acid
3-hydroxy-2-(c-hydroxycarbonimidoyl)-6-methoxy-5-methyl-4-[(1e)-prop-1-en-1-yl]benzoic acid
5-hydroxy-3-(4-hydroxyphenyl)-4-phenylpyrrol-2-one
(3Z)-3-(2-amino-4,6-dioxo-5,8-dihydro-1H-pteridin-7-ylidene)-2-oxopropanoic acid
{"Ingredient_id": "HBIN009763","Ingredient_name": "(3Z)-3-(2-amino-4,6-dioxo-5,8-dihydro-1H-pteridin-7-ylidene)-2-oxopropanoic acid","Alias": "(3Z)-3-(2-amino-4,6-dioxo-5,8-dihydro-1H-pteridin-7-ylidene)-2-oxo-propanoic acid; (3Z)-3-(2-amino-4,6-diketo-5,8-dihydro-1H-pteridin-7-ylidene)-2-keto-propionic acid; 3-(2-Amino-4,5,6,8-tetrahydro-4,6-dioxopteridin-7(3H)-ylidene)-2-oxopropionic acid; 7449-03-8; EINECS 231-214-4","Ingredient_formula": "C9H7N5O5","Ingredient_Smile": "C(=C(C(=O)O)O)C1=NC2=C(C(=O)NC(=N2)N)NC1=O","Ingredient_weight": "265.18 g/mol","OB_score": "10.6551606","CAS_id": "7449/3/8","SymMap_id": "SMIT12555","TCMID_id": "NA","TCMSP_id": "MOL011684","TCM_ID_id": "NA","PubChem_id": "136217907","DrugBank_id": "NA"}
anhydrolycorin-6-one
{"Ingredient_id": "HBIN016169","Ingredient_name": "anhydrolycorin-6-one","Alias": "NA","Ingredient_formula": "C16H11NO3","Ingredient_Smile": "C1CN2C3=C(C=CC=C31)C4=CC5=C(C=C4C2=O)OCO5","Ingredient_weight": "NA","OB_score": "NA","CAS_id": "NA","SymMap_id": "NA","TCMID_id": "1276","TCMSP_id": "NA","TCM_ID_id": "NA","PubChem_id": "NA","DrugBank_id": "NA"}
