Piperolactam A (BioDeep_00000360439)

Main id: BioDeep_00000017557

 

PANOMIX_OTCML-2023


代谢物信息卡片


15-hydroxy-14-methoxy-10-azatetracyclo[7.6.1.0^{2,7}.0^{12,16}]hexadeca-1(15),2,4,6,8,12(16),13-heptaen-11-one

化学式: C16H11NO3 (265.07388960000003)
中文名称: 马兜铃内酰胺 FI
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: COC1=C(C2=C3C(=C1)C(=O)NC3=CC4=CC=CC=C42)O
InChI: InChI=1S/C16H11NO3/c1-20-12-7-10-13-11(17-16(10)19)6-8-4-2-3-5-9(8)14(13)15(12)18/h2-7,18H,1H3,(H,17,19)



数据库引用编号

6 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Yuan-Kun Zheng, Bao-Jun Su, Ya-Qi Wang, Heng-Shan Wang, Hai-Bing Liao, Dong Liang. New Tyramine- and Aporphine-Type Alkamides with NO Release Inhibitory Activities from Piper puberulum. Journal of natural products. 2021 04; 84(4):1316-1325. doi: 10.1021/acs.jnatprod.1c00055. [PMID: 33822610]
  • Plaban Bhattacharya, Achintya Saha, Souvik Basak. Discovery of nano-piperolactam A: A nonsteroidal contraceptive lead acting through down-regulation of interleukins. Nanomedicine : nanotechnology, biology, and medicine. 2019 06; 18(?):347-358. doi: 10.1016/j.nano.2018.10.011. [PMID: 30412768]
  • Plaban Bhattacharya, Subhasish Mondal, Souvik Basak, Pradeep Das, Achintya Saha, Tanmoy Bera. In Vitro susceptibilities of wild and drug resistant Leishmania donovani amastigotes to piperolactam A loaded hydroxypropyl-β-cyclodextrin nanoparticles. Acta tropica. 2016 Jun; 158(?):97-106. doi: 10.1016/j.actatropica.2016.02.017. [PMID: 26940000]
  • Hai-peng Lei, Xian-qiang Chen, Chun-feng Qiao, Yang Liu, Jing Zhao. [Chemical constituents from twigs of Piper hancei]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials. 2014 Jan; 37(1):69-71. doi: . [PMID: 25090708]
  • Joa Kyum Kim, Young Ha Kim, Ho Tae Nam, Bum Tae Kim, Jung-Nyoung Heo. Total synthesis of aristolactams via a one-pot suzuki-miyaura coupling/aldol condensation cascade reaction. Organic letters. 2008 Aug; 10(16):3543-6. doi: 10.1021/ol801291k. [PMID: 18642834]
  • Yi-Nan Zhang, Xiang-Gen Zhong, Zong-Ping Zheng, Xu-Dong Hu, Jian-Ping Zuo, Li-Hong Hu. Discovery and synthesis of new immunosuppressive alkaloids from the stem of Fissistigma oldhamii (Hemsl.) Merr. Bioorganic & medicinal chemistry. 2007 Jan; 15(2):988-96. doi: 10.1016/j.bmc.2006.10.034. [PMID: 17081761]
  • Rachel Mata, Iliana Morales, Olga Pérez, Isabel Rivero-Cruz, Laura Acevedo, Isolda Enriquez-Mendoza, Robert Bye, Scott Franzblau, Barbara Timmermann. Antimycobacterial compounds from Piper sanctum. Journal of natural products. 2004 Dec; 67(12):1961-8. doi: 10.1021/np0401260. [PMID: 15620234]
  • Y C Chia, F R Chang, C M Teng, Y C Wu. Aristolactams and dioxoaporphines from Fissistigma balansae and Fissistigma oldhamii. Journal of natural products. 2000 Aug; 63(8):1160-3. doi: 10.1021/np000063v. [PMID: 10978218]
  • N J Sun, M Antoun, C J Chang, J M Cassady. New cytotoxic aristolactams from Pararistolochia flos-avis. Journal of natural products. 1987 Sep; 50(5):843-6. doi: 10.1021/np50053a011. [PMID: 3437282]