Nigerloxin (BioDeep_00000911231)
代谢物信息卡片
化学式: C13H15NO5 (265.095)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC=CC1=C(C(=C(C(=C1O)C(=O)N)C(=O)O)OC)C
InChI: InChI=1S/C13H15NO5/c1-4-5-7-6(2)11(19-3)9(13(17)18)8(10(7)15)12(14)16/h4-5,15H,1-3H3,(H2,14,16)(H,17,18)/b5-4+
描述信息
A member of the class of benzoic acids that is benzoic acid which is substituted at positions 2, 3, 4, 5, and 6 by carbamoyl, hydroxy, E)-prop-1-en-1-yl, methyl, and methoxy groups, respectively. Obtained from solid-state fermentation of Aspergillus niger CFR-W-105, it inhibits soy bean lipoxygenase-1 (LOX-1) and rat lens aldose reductase (RLAR). It also shows free radical scavenging activity.
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1 个代谢物同义名
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代谢反应
0 个相关的代谢反应过程信息。
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1 个相关的物种来源信息
- 5061 - Aspergillus niger: 10.7164/ANTIBIOTICS.55.789
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
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文献列表
- Bharathinagar S Suresha, Krishnapura Srinivasan. Fungal metabolite nigerloxin ameliorates diabetic nephropathy and gentamicin-induced renal oxidative stress in experimental rats.
Naunyn-Schmiedeberg's archives of pharmacology.
2014 Sep; 387(9):849-59. doi:
10.1007/s00210-014-1001-5. [PMID: 24915992] - Bharathinagar S Suresha, Krishnapura Srinivasan. Antioxidant potential of fungal metabolite nigerloxin during eye lens abnormalities in galactose-fed rats.
Current eye research.
2013 Oct; 38(10):1064-71. doi:
10.3109/02713683.2013.802810. [PMID: 23767695] - Bharathinagar S Suresha, Kuntavalli Y Vasantha, Avinash P Sattur, Krishnapura Srinivasan. Beneficial influence of fungal metabolite nigerloxin on diabetes-induced oxidative stress in experimental rats.
Canadian journal of physiology and pharmacology.
2013 Feb; 91(2):149-56. doi:
10.1139/cjpp-2012-0241. [PMID: 23458199] - Bharathinagar S Suresha, Avinash P Sattur, Krishnapura Srinivasan. Beneficial influence of fungal metabolite nigerloxin on eye lens abnormalities in experimental diabetes.
Canadian journal of physiology and pharmacology.
2012 Apr; 90(4):387-94. doi:
10.1139/y11-135. [PMID: 22423974] - K C Sekhar Rao, A G Appu Rao, A P Sattur. A spectroscopic study of the interaction of nigerloxin, a fungal metabolite, with serum albumin.
Lipids.
2004 Feb; 39(2):173-7. doi:
10.1007/s11745-004-1216-4. [PMID: 15134145]
