Exact Mass: 195.1259
Exact Mass Matches: 195.1259
Found 500 metabolites which its exact mass value is equals to given mass value 195.1259,
within given mass tolerance error 0.05 dalton. Try search metabolite list with more accurate mass tolerance error
0.01 dalton.
Tyrosine methylester
Tyrosine methylester, also known as Tyrosine methyl ester hydrochloride, (L)-isomer or Tyr-ome, is classified as a tyrosine or a Tyrosine derivative. Tyrosines are compounds containing tyrosine or a derivative thereof resulting from reaction of tyrosine at the amino group or the carboxy group, or from the replacement of any hydrogen of glycine by a heteroatom. Tyrosine methylester is considered to be a slightly soluble (in water) and a very weak acidic compound. Tyrosine methylester can be found in humans. KEIO_ID T032 H-Tyr-OMe, an amino acid, is an endogenous metabolite[1].
Metyrosine
Metyrosine is only found in individuals that have used or taken this drug. It is an inhibitor of the enzyme tyrosine 3-monooxygenase, and consequently of the synthesis of catecholamines. It is used to control the symptoms of excessive sympathetic stimulation in patients with pheochromocytoma. (Martindale, The Extra Pharmacopoeia, 30th ed)Metyrosine inhibits tyrosine hydroxylase, which catalyzes the first transformation in catecholamine biosynthesis, i.e., the conversion of tyrosine to dihydroxyphenylalanine (DOPA). Because the first step is also the rate-limiting step, blockade of tyrosine hydroxylase activity results in decreased endogenous levels of catecholamines and their synthesis. This consequently, depletes the levels of the catecholamines dopamine, adrenaline and noradrenaline in the body,usually measured as decreased urinary excretion of catecholamines and their metabolites. One main end result of the catecholamine depletion is a decrease in blood presure. C - Cardiovascular system > C02 - Antihypertensives > C02K - Other antihypertensives > C02KB - Tyrosine hydroxylase inhibitors C78274 - Agent Affecting Cardiovascular System > C270 - Antihypertensive Agent C471 - Enzyme Inhibitor > C2155 - Tyrosine Hydroxylase Inhibitor D004791 - Enzyme Inhibitors C471 - Enzyme Inhibitor
2-Phenyl-1,3-propanediol monocarbamate
2-Phenyl-1,3-propanediol monocarbamate is a metabolite of felbamate. Felbamate (marketed under the brand name Felbatol by MedPointe) is an anti-epileptic drug used in the treatment of epilepsy. It is used to treat partial seizures (with and without generalization) in adults and partial and generalized seizures associated with Lennox-Gastaut syndrome in children. However, an increased risk of potentially fatal aplastic anemia and/or liver failure limit the drugs usage to severe refractory epilepsy. (Wikipedia)
L-Homotyrosine
COVID info from PDB, Protein Data Bank Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS
alpha-[3-(Nitrosoamino)propyl]-3-pyridinemethanol
alpha-[3-(Nitrosoamino)propyl]-3-pyridinemethanol is considered to be slightly soluble (in water) and acidic
3-Methyl-l-tyrosine
A tyrosine derivative that is L-tyrosine in which the hydrogen at position 3 on the phenyl ring is replaced by a methyl group.
Methacholine chloride
D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents > D010277 - Parasympathomimetics D018377 - Neurotransmitter Agents > D018678 - Cholinergic Agents > D018679 - Cholinergic Agonists D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents > D008916 - Miotics D019141 - Respiratory System Agents > D016085 - Bronchoconstrictor Agents Methacholine (Acetyl-β-methylcholine) choride is a potent muscarinic-3 (M3) agonist. Methacholine choride acts directly on acetylcholine receptors on smooth muscle causing bronchoconstriction and airway narrowing. Methacholine choride shows a high sensitivity to identify bronchial hyperresponsiveness (BHR). Methacholine choride can be used to measure airway hyperresponsiveness (AHR) as a diagnostic aid in the assessment of individuals with asthma-like symptoms and normal resting expiratory flow rates[1][2][3][4].
Surinamine
D010592 - Pharmaceutic Aids > D011310 - Preservatives, Pharmaceutical > D010226 - Parabens
N-Acetyldopamine
N-Acetyldopamine also known as NADA is an acetylated form of dopamine. It is an endogenously produced derivative or metabolite of dopamine. It belongs to the family of compounds known as catecholamines and derivatives. These are compounds containing 4-(2-aminoethyl) pyrocatechol [4-(2-aminoethyl) benzene-1,2-diol] or a derivative thereof. While NADA has been found in the human liver, kidney, and urine, it is unclear what its role is in mammal physiology (PMID: 16179545). NADA exists in both free and conjugated (glucuronide) forms. Conjugated NADA accounts for about 90\\\% of the total excretion of NADA. Urinary excretion of total N-acetyldopamine averages 0.485 micromoles/day in healthy humans (PMID: 6513727). The concentration of NADA is thirteen times higher in children with neuroblastoma than in normal subjects (PMID: 1321164). NADA is known to be a sepiapterin reductase inhibitor (PMID: 16179545). N-acetyldopamine has been shown to inhibit lipopolysaccharide-induced lipid peroxidation in rat brains (PMID: 16179545). N-acetyldopamine (NADA) is a catecholamine that is used by insects as sclerotizing precursors to harden their cuticle[1].
2,5-Dibutyl-4-methyloxazole
2,5-Dibutyl-4-methyloxazole is found in cocoa and cocoa products. 2,5-Dibutyl-4-methyloxazole is a constituent of cocoa butter. Constituent of cocoa butter. 2,5-Dibutyl-4-methyloxazole is found in cocoa and cocoa products.
5-Ethyl-2-hexyl-4-methyloxazole
5-Ethyl-2-hexyl-4-methyloxazole is found in potato. 5-Ethyl-2-hexyl-4-methyloxazole is a volatile constituent of French fried potato. Volatile constituent of French fried potato. 5-Ethyl-2-hexyl-4-methyloxazole is found in potato.
4-Methyl-2-pentyl-5-propyloxazole
Not reported in nature. Not reported in nature
4-Ethyl-2-hexyl-5-methyloxazole
Not reported in nature. Not reported in nature
4,5-Dimethyl-2-heptyloxazole
Not reported in nature. Not reported in nature
N-methyl-4,6,7-trihydroxy-1,2,3,4-tetrahydroisoquinoline
This compound belongs to the family of Isoquinolines and Derivatives. These are aromatic polycyclic compounds containing an isoquinoline moiety, which consists of a benzene ring fused to a pyridine ring and forming benzo[c]pyridine
1-Amino-3-hydroxymethyl-5-methyl-adamantane
1-Amino-3-hydroxymethyl-5-methyl-adamantane is a metabolite of memantine. Memantine is the first in a novel class of Alzheimers disease medications acting on the glutamatergic system by blocking NMDA glutamate receptors. It was first synthesized by Eli Lilly and Company in 1968. Memantine is marketed under the brands Axura and Akatinol by Merz, Namenda by Forest, Ebixa and Abixa by Lundbeck and Memox by Unipharm. Despite years of research, there is little evidence of effect in mild to moderate Alzheimers disease. (Wikipedia)
3-Amino-1-hydroxy-5,7-dimethyl-adamantane
3-Amino-1-hydroxy-5,7-dimethyl-adamantane is a metabolite of memantine. Memantine is the first in a novel class of Alzheimers disease medications acting on the glutamatergic system by blocking NMDA glutamate receptors. It was first synthesized by Eli Lilly and Company in 1968. Memantine is marketed under the brands Axura and Akatinol by Merz, Namenda by Forest, Ebixa and Abixa by Lundbeck and Memox by Unipharm. Despite years of research, there is little evidence of effect in mild to moderate Alzheimers disease. (Wikipedia)
2-hydroxymexiletine
2-hydroxymexiletine is a metabolite of mexiletine. Mexiletine (sold under the trade name Mexitil) belongs to the Class IB anti-arrhythmic group of medicines. It is used to treat arrhythmias within the heart, or seriously irregular heartbeats. It slows conduction in the heart and makes the heart tissue less sensitive. Dizziness, heartburn, nausea, nervousness, trembling, unsteadiness are common side effects. It is available in injection and capsule form. (Wikipedia)
p-hydroxymexiletine
p-hydroxymexiletine is a metabolite of mexiletine. Mexiletine (sold under the trade name Mexitil) belongs to the Class IB anti-arrhythmic group of medicines. It is used to treat arrhythmias within the heart, or seriously irregular heartbeats. It slows conduction in the heart and makes the heart tissue less sensitive. Dizziness, heartburn, nausea, nervousness, trembling, unsteadiness are common side effects. It is available in injection and capsule form. (Wikipedia)
Meglumine
Meglumine, also known as megluminum or methylglucamine, belongs to the class of organic compounds known as hexoses. These are monosaccharides in which the sugar unit is a is a six-carbon containing moeity. Meglumine is soluble (in water) and a very weakly acidic compound (based on its pKa).
2-Amino-4-hydroxy-6,7-dimethyl-5,6,7,8-tetrahydropteridine
Racemetirosine
C78274 - Agent Affecting Cardiovascular System > C270 - Antihypertensive Agent D004791 - Enzyme Inhibitors C471 - Enzyme Inhibitor
[3-(2-Aminopropyl)-6-methylidenecyclohexa-1,3-dien-1-yl]methanediol
1R-2-(2,6,6-trimethyl-4-oxo-2-cyclohexenyl)ethanamide|glaucenamide
N-[2-(3,4-dimethoxyphenyl)ethylidene]hydroxylamine
N-A-BOC-N-D-Z-D-LYSINE
D000890 - Anti-Infective Agents > D000977 - Antiparasitic Agents > D000981 - Antiprotozoal Agents D004791 - Enzyme Inhibitors > D011480 - Protease Inhibitors
1-methyl-1,2,3,4-tetrahydroisoquinoline-4,6,7-triol
1,2,3,5,6,8a-Hexahydro-alpha-propyl-8-indolizinemethanol
L-beta-Homotyrosine
Acquisition and generation of the data is financially supported in part by CREST/JST.
2,2-(p-Tolylazanediyl)diethanol
CONFIDENCE standard compound; INTERNAL_ID 142; DATASET 20200303_ENTACT_RP_MIX500; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4749; ORIGINAL_PRECURSOR_SCAN_NO 4747 CONFIDENCE standard compound; INTERNAL_ID 142; DATASET 20200303_ENTACT_RP_MIX500; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4763; ORIGINAL_PRECURSOR_SCAN_NO 4760 CONFIDENCE standard compound; INTERNAL_ID 142; DATASET 20200303_ENTACT_RP_MIX500; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4766; ORIGINAL_PRECURSOR_SCAN_NO 4764 CONFIDENCE standard compound; INTERNAL_ID 142; DATASET 20200303_ENTACT_RP_MIX500; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4776; ORIGINAL_PRECURSOR_SCAN_NO 4775 CONFIDENCE standard compound; INTERNAL_ID 142; DATASET 20200303_ENTACT_RP_MIX500; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4785; ORIGINAL_PRECURSOR_SCAN_NO 4783 CONFIDENCE standard compound; INTERNAL_ID 142; DATASET 20200303_ENTACT_RP_MIX500; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4781; ORIGINAL_PRECURSOR_SCAN_NO 4778
6,7-Dimethyltetrahydropterin
N-Acetyldopamine
A secondary carboxamide obtained by formal condensation of the carboxy group of acetic acid with the amino group of dopamine. A dopamine metabolite. N-acetyldopamine (NADA) is a catecholamine that is used by insects as sclerotizing precursors to harden their cuticle[1].
2-amino-3-(4-hydroxy-2-methylphenyl)propanoic acid
((3R,4S)-4-(3-fluorophenyl)pyrrolidin-3-yl)methanol
Methyl 4-amino-4,5,6,7-tetrahydrobenzofuran-3-carboxylate
(5-METHYL-PYRIDIN-2-YLOXY)-ACETIC ACID ETHYL ESTER
Carpronium chloride
C78272 - Agent Affecting Nervous System > C47796 - Cholinergic Agonist
Ethyl 5-formyl-2,4-dimethyl-1H-pyrrole-3-carboxylate
Ethyl 5,6,7,8-tetrahydroimidazo[1,2-a]pyrazine-2-carboxylate hydrochloride
ethyl 4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxylate
tert-butyl (1R,4S)-5-azabicyclo[2.2.1]hept-2-ene-5-carboxylate
3-AMINO-3-(2-HYDROXY-3-METHYL-PHENYL)-PROPIONIC ACID
Urea, N-(4-methoxy-2-methyl-3-pyridinyl)-N-methyl- (9CI)
4,5,6,7-Tetrahydro-1H-pyrazolo[4,3-c]pyridine-3-carboxylic acid ethyl ester
5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-1H-1,2,3-TRIAZOLE
2-amino-6-(2-methylpropyl)pyrimidine-4-carboxylic acid
Hydrazinecarboxamide,2-[2-(1-cyclohexen-1-yl)-1-methylethylidene]-
3-(5-Formyl-2,4-dimethyl-1H-pyrrol-3-yl)propanoic acid
ethyl 4-ethyl-3,5-dimethyl-1h-pyrrole-2-carboxylate
methyl 1-methyl-4-propionyl-1H-pyrrole-2-carboxylate
formic acid, compound with 2,2,2-nitrilotris[ethanol] (1:1)
8-hydroxy-8-(trifluoromethyl)-3-azabicyclo[3.2.1]octane
1H-Pyrrole-2-carboxylicacid, 4-formyl-3,5-dimethyl-, ethyl ester
3-Pyridinecarboxylicacid, 1,4-dihydro-2,6-dimethyl-4-oxo-, ethyl ester
ETHYL 2,4-DIMETHYL-6-OXO-1,6-DIHYDROPYRIDINE-3-CARBOXYLATE
(R)-methyl 2-(isopropylamino)butanoate hydrochloride
2-AMINO-1-(2,3-DIHYDROBENZO[1,4]DIOXIN-6-YL)ETHANOL
1-(2-THIENYLMETHYL)PIPERIDIN-4-YL]METHANOL HYDROCHLORIDE
Ethyl 5,6,7,8-Tetrahydroimidazo[1,2-a]pyrazine-2-carboxylate
3-AMINO-3-(4-HYDROXY-3-METHYL-PHENYL)-PROPIONIC ACID
3-(piperidin-1-ylcarbonyl)-1H-1,2,4-triazol-5-amine(SALTDATA: FREE)
1,2-Benzisoxazole-3-carboxylicacid, 4,5,6,7-tetrahydro-, ethyl ester
(S)-1-((3AR,4R,6AS)-5-BENZYL-2,2-DIMETHYL-TETRAHYDRO-[1,3]DIOXOLO[4,5-C]PYRROL-4-YL)-ETHANE-1,2-DIOL
5-Pyrimidinecarboxylicacid,2-amino-4,6-dimethyl-,ethylester(9CI)
(4-METHYL-PYRIDIN-2-YLOXY)-ACETIC ACID ETHYL ESTER
methyl 4-formyl-1,2,5-trimethylpyrrole-3-carboxylate
Benzoic acid, 5-amino-2-methoxy-, ethyl ester (9CI)
8-amino-8-tricyclo[5,2,1,0(2,6)]decanecarboxylic acid
Carbamic acid, 4-pyridazinyl-, 1,1-dimethylethyl ester (9CI)
3,4-DIETHYL-1H-PYRROLE-2-CARBOXYLIC ACID ETHYL ESTER
Urea, N-(1,2-dihydro-2-oxo-3-pyridinyl)-N-propyl- (9CI)
Ethyl 5,6,7,8-tetrahydroimidazo[1,5-a]pyrazine-1-carboxylate
Tricyclo[3.3.1.13,7]decane-1-MethanaMine, N-hydroxy-α-Methyl-
5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-oxazole
6-methyl-2-(propan-2-ylamino)pyrimidine-4-carboxylic acid
(-)-(1S,4R)-N-FMOC-4-AMINOCYCLOPENT-2-ENECARBOXYLICACID
tert-Butyl 2-amino-2-methylpropanoate hydrochloride
methyl 4-acetyl-2,5-dimethyl-1h-pyrrole-3-carboxylate
6-methyl-2-(propylamino)pyrimidine-4-carboxylic acid
propan-2-yl 3-(hydroxymethyl)pyridine-2-carboxylate
1H-Isoindole-1,3(2H)-dione,3a,4,7,7a-tetrahydro-2-(2-hydroxyethyl)-
tert-Butyl 2-azabicyclo[2.2.1]hept-5-ene-2-carboxylate
2-Methyl-6-(2-phenylethenyl)pyridine
(E/Z)-SIB-1893 is a racemic compound of (E)-SIB-1893 and (Z)-SIB-1893 isomers. (E)-SIB-1893 is a selective non-competitive metabotropic glutamate subtype 5 receptor (mGluR5) antagonist[1].
2-Amino-4-hydroxy-6,7-dimethyl-5,6,7,8-tetrahydropteridine
N-(2-aminoethyl)ethane-1,2-diamine;2-(chloromethyl)oxirane
Racemetirosine
C78274 - Agent Affecting Cardiovascular System > C270 - Antihypertensive Agent D004791 - Enzyme Inhibitors C471 - Enzyme Inhibitor
EU-0100093
N-acetyldopamine (NADA) is a catecholamine that is used by insects as sclerotizing precursors to harden their cuticle[1].
1-Amino-3-hydroxymethyl-5-methyl-adamantane
1-Amino-3-hydroxymethyl-5-methyl-adamantane is a metabolite of memantine. Memantine is the first in a novel class of Alzheimers disease medications acting on the glutamatergic system by blocking NMDA glutamate receptors. It was first synthesized by Eli Lilly and Company in 1968. Memantine is marketed under the brands Axura and Akatinol by Merz, Namenda by Forest, Ebixa and Abixa by Lundbeck and Memox by Unipharm. Despite years of research, there is little evidence of effect in mild to moderate Alzheimers disease. (Wikipedia)
(2S)-2-ammonio-3-(4-hydroxy-3-methylphenyl)propanoate
Oxotremorine M
D018377 - Neurotransmitter Agents > D018678 - Cholinergic Agents > D018679 - Cholinergic Agonists
Metyrosine
An L-tyrosine derivative that consists of L-tyrosine bearing an additional methyl substituent at position 2. An inhibitor of the enzyme tyrosine 3-monooxygenase, and consequently of the synthesis of catecholamines. It is used to control the symptoms of excessive sympathetic stimulation in patients with pheochromocytoma. C - Cardiovascular system > C02 - Antihypertensives > C02K - Other antihypertensives > C02KB - Tyrosine hydroxylase inhibitors C471 - Enzyme Inhibitor > C2155 - Tyrosine Hydroxylase Inhibitor D004791 - Enzyme Inhibitors
3-methyl-L-tyrosine zwitterion
An amino acid zwitterion resulting from a transfer of a proton from the carboxy to the amino group of 3-methyl-L-tyrosine; major species at pH 7.3.
N-acetyloctopamine
A member of the class of tyramines that is octopamine in which one of the amino hydrogens is replaced by an acetyl group. It is a metabolite of octopamine which is found in the brains of ants and fruit flies.
