Meglumine (BioDeep_00000169742)
human metabolite
代谢物信息卡片
(2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentol
化学式: C7H17NO5 (195.1106672)
中文名称: N-甲基-D-葡糖胺
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CNCC(C(C(C(CO)O)O)O)O
InChI: InChI=1S/C7H17NO5/c1-8-2-4(10)6(12)7(13)5(11)3-9/h4-13H,2-3H2,1H3/t4-,5+,6+,7+/m0/s1
描述信息
Meglumine, also known as megluminum or methylglucamine, belongs to the class of organic compounds known as hexoses. These are monosaccharides in which the sugar unit is a is a six-carbon containing moeity. Meglumine is soluble (in water) and a very weakly acidic compound (based on its pKa).
同义名列表
数据库引用编号
9 个数据库交叉引用编号
- ChEBI: CHEBI:59732
- PubChem: 8567
- HMDB: HMDB0240291
- DrugBank: DB09415
- ChEMBL: CHEMBL1200570
- Wikipedia: Meglumine
- MeSH: Meglumine
- chemspider: 8249
- CAS: 6284-40-8
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Shi-Xiong Peng, Cong Wei, Jing-Ying Lei, Teng Zhang, Yan-Bing Ding. [Network Meta-analysis of Chinese medicine injections for activating blood and resolving stasis in adjuvant treatment of acute ischemic stroke].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
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Neuroimmunomodulation.
2023; 30(1):315-324. doi:
10.1159/000534607. [PMID: 37899033] - Qin Yang, Tiantian Tan, Qin He, Chenqi Guo, Dan Chen, Yulu Tan, Jiaxing Feng, Xu Song, Tao Gong, Jia Li. Combined Amphiphilic Silybin Meglumine Nanosuspension Effective Against Hepatic Fibrosis in Mice Model.
International journal of nanomedicine.
2023; 18(?):5197-5211. doi:
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Investigative radiology.
2022 05; 57(5):283-292. doi:
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International immunopharmacology.
2022 May; 106(?):108602. doi:
10.1016/j.intimp.2022.108602. [PMID: 35131571] - Xavier Violas, Marlène Rasschaert, Robin Santus, Cécile Factor, Claire Corot, Sarah Catoen, Jean-Marc Idée, Philippe Robert. Small Brain Lesion Enhancement and Gadolinium Deposition in the Rat Brain: Comparison Between Gadopiclenol and Gadobenate Dimeglumine.
Investigative radiology.
2022 02; 57(2):130-139. doi:
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Computational and mathematical methods in medicine.
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2021 Jul; 26(6):701-708. doi:
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2021 Apr; 31(4):2490-2496. doi:
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Radiology.
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Investigative radiology.
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Journal of magnetic resonance imaging : JMRI.
2020 02; 51(2):607-614. doi:
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Investigative radiology.
2020 01; 55(1):30-37. doi:
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2019 10; 44(10):3336-3349. doi:
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Clinical radiology.
2019 Oct; 74(10):797-804. doi:
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Magnetic resonance in medicine.
2019 07; 82(1):387-394. doi:
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Transplantation.
2019 06; 103(6):e159-e163. doi:
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Investigative radiology.
2019 05; 54(5):312-318. doi:
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Neuroradiology.
2019 May; 61(5):535-544. doi:
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European radiology.
2019 Apr; 29(4):1922-1930. doi:
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Critical reviews in toxicology.
2019 03; 49(3):262-279. doi:
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BioMed research international.
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Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova.
2019; 119(11. Vyp. 2):74-79. doi:
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Cerebrovascular diseases (Basel, Switzerland).
2019; 48(3-6):140-148. doi:
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Radiology.
2018 09; 288(3):703-709. doi:
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Radiology.
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JACC. Cardiovascular imaging.
2018 08; 11(8):1045-1055. doi:
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Research in veterinary science.
2018 Aug; 119(?):52-55. doi:
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Radiology.
2018 08; 288(2):424-433. doi:
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2018 Jul; 103(?):1609-1616. doi:
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2018 May; 16(5):366-374. doi:
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Experimental parasitology.
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Investigative radiology.
2018 02; 53(2):110-118. doi:
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Regulatory toxicology and pharmacology : RTP.
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2018 Jan; 117(1):273-286. doi:
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Radiology.
2018 01; 286(1):113-119. doi:
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PloS one.
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2017 Dec; 42(24):4733-4737. doi:
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Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
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Phytotherapy research : PTR.
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Veterinary immunology and immunopathology.
2017 Sep; 191(?):60-67. doi:
10.1016/j.vetimm.2017.08.004. [PMID: 28895868] - Jin-Seok Choi, Sang-Eun Lee, Woo Suk Jang, Jong Chan Byeon, Jeong-Sook Park. Tadalafil solid dispersion formulations based on PVP/VA S-630: Improving oral bioavailability in rats.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.
2017 Aug; 106(?):152-158. doi:
10.1016/j.ejps.2017.05.065. [PMID: 28579005] - Jean-Luc Daire, Benjamin Leporq, Valérie Vilgrain, Bernard E Van Beers, Sabine Schmidt, Catherine M Pastor. Liver Perfusion Modifies Gd-DTPA and Gd-BOPTA Hepatocyte Concentrations Through Transfer Clearances Across Sinusoidal Membranes.
European journal of drug metabolism and pharmacokinetics.
2017 Aug; 42(4):657-667. doi:
10.1007/s13318-016-0382-x. [PMID: 27778300] - Thomas Frenzel, Chirag Apte, Gregor Jost, Laura Schöckel, Jessica Lohrke, Hubertus Pietsch. Quantification and Assessment of the Chemical Form of Residual Gadolinium in the Brain After Repeated Administration of Gadolinium-Based Contrast Agents: Comparative Study in Rats.
Investigative radiology.
2017 07; 52(7):396-404. doi:
10.1097/rli.0000000000000352. [PMID: 28125438] - Joaquim Marcoval, Rosa M Penín. Evolution of cutaneous leishmaniasis in the last 30 years in a tertiary hospital of the European Mediterranean coast.
International journal of dermatology.
2017 Jul; 56(7):750-753. doi:
10.1111/ijd.13588. [PMID: 28247922] - Wei Liu, Jing-Li Chen, Henry Liu, Hong Yan. Effects of meglumine cyclic adenylate pretreatment on systemic inflammatory response syndrome induced by lipopolysaccharide in rats.
Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban.
2017 Jun; 37(3):332-336. doi:
10.1007/s11596-017-1736-6. [PMID: 28585140] - John P Prybylski, Richard C Semelka, Michael Jay. The stability of gadolinium-based contrast agents in human serum: A reanalysis of literature data and association with clinical outcomes.
Magnetic resonance imaging.
2017 05; 38(?):145-151. doi:
10.1016/j.mri.2017.01.006. [PMID: 28089499] - Gregory J Wilson, Charles S Springer, Sarah Bastawrous, Jeffrey H Maki. Human whole blood 1 H2 O transverse relaxation with gadolinium-based contrast reagents: Magnetic susceptibility and transmembrane water exchange.
Magnetic resonance in medicine.
2017 05; 77(5):2015-2027. doi:
10.1002/mrm.26284. [PMID: 27297589] - Ignacio Ayala, Luis Jesus Bernal, Juan Diego Garcia-Martinez, Miguel Angel Gomez, Jose Antonio Navarro, Antonio Bernabe. An Atypical Case of Leishmaniasis Associated with Chronic Duodenitis in a Dog.
Journal of the American Animal Hospital Association.
2017 Mar; 53(2):101-106. doi:
10.5326/jaaha-ms-6401. [PMID: 28282232] - María P Elizalde-González, Esmeralda García-Díaz, Mario González-Perea, Jürgen Mattusch. Removal of gadolinium-based contrast agents: adsorption on activated carbon.
Environmental science and pollution research international.
2017 Mar; 24(9):8164-8175. doi:
10.1007/s11356-017-8491-x. [PMID: 28144867] - Luis Pardo-Marín, Silvia Martínez-Subiela, Josep Pastor, Asta Tvarijonaviciute, Juan Diego Garcia-Martinez, Sergi Segarra, José Joaquín Cerón. Evaluation of various biomarkers for kidney monitoring during canine leishmaniosis treatment.
BMC veterinary research.
2017 Jan; 13(1):31. doi:
10.1186/s12917-017-0956-0. [PMID: 28114941] - V D Scripko, A L Kovalenko, V A Zaplutonov. [Microelemental homeostasis correction of and oxidative stress in patients with acute intestinal obstruction].
Khirurgiia.
2017 ; ?(6):55-59. doi:
10.17116/hirurgia2017655-59. [PMID: 28638015] - Mahmoodreza Moein, Gholamreza Hatam, Razieh Taghavi-Moghadam, Mohammad M Zarshenas. Antileishmanial Activities of Greek Juniper (Juniperus excelsa M.Bieb.) Against Leishmania major Promastigotes.
Journal of evidence-based complementary & alternative medicine.
2017 Jan; 22(1):31-36. doi:
10.1177/2156587215623435. [PMID: 26747836] - A Furlan, O N Close, A A Borhani, Y H Wu, M T Heller. Respiratory-motion artefacts in liver MRI following injection of gadoxetate disodium and gadobenate dimeglumine: an intra-individual comparative study in cirrhotic patients.
Clinical radiology.
2017 Jan; 72(1):93.e1-93.e6. doi:
10.1016/j.crad.2016.08.005. [PMID: 27633725] - Luiz Filipe Gonçalves Oliveira, Franklin Souza-Silva, Léa Cysne-Finkelstein, Kíssila Rabelo, Juliana Fernandes Amorim, Adriana de Souza Azevedo, Saulo Cabral Bourguignon, Vitor Francisco Ferreira, Marciano Viana Paes, Carlos Roberto Alves. Evidence for Tissue Toxicity in BALB/c Exposed to a Long-Term Treatment with Oxiranes Compared to Meglumine Antimoniate.
BioMed research international.
2017; 2017(?):9840210. doi:
10.1155/2017/9840210. [PMID: 28798938] - Damián Escribano, Asta Tvarijonaviciute, Meric Kocaturk, Jose Joaquín Cerón, Luis Pardo-Marín, Alejandro Torrecillas, Zeki Yilmaz, Silvia Martínez-Subiela. Serum apolipoprotein-A1 as a possible biomarker for monitoring treatment of canine leishmaniosis.
Comparative immunology, microbiology and infectious diseases.
2016 Dec; 49(?):82-87. doi:
10.1016/j.cimid.2016.10.002. [PMID: 27865270] - Richard C Semelka, Joana Ramalho, Ami Vakharia, Mamdoh AlObaidy, Lauren M Burke, Michael Jay, Miguel Ramalho. Gadolinium deposition disease: Initial description of a disease that has been around for a while.
Magnetic resonance imaging.
2016 Dec; 34(10):1383-1390. doi:
10.1016/j.mri.2016.07.016. [PMID: 27530966] - Camila Peres Rubio, Silvia Martinez-Subiela, Asta Tvarijonaviciute, Josefa Hernández-Ruiz, Luis Pardo-Marin, Sergi Segarra, José Joaquín Ceron. Changes in serum biomarkers of oxidative stress after treatment for canine leishmaniosis in sick dogs.
Comparative immunology, microbiology and infectious diseases.
2016 Dec; 49(?):51-57. doi:
10.1016/j.cimid.2016.09.003. [PMID: 27865264] - Yan Cao, Yang Zhang, George Shih, Yan Zhang, Andrew Bohmart, Elizabeth M Hecht, Martin R Prince. Effect of Renal Function on Gadolinium-Related Signal Increases on Unenhanced T1-Weighted Brain Magnetic Resonance Imaging.
Investigative radiology.
2016 11; 51(11):677-682. doi:
10.1097/rli.0000000000000294. [PMID: 27272543] - Philipp Riffel, Frank G Zoellner, Johannes Budjan, Robert Grimm, Tobias K Block, Stefan O Schoenberg, Daniel Hausmann. 'One-Stop Shop': Free-Breathing Dynamic Contrast-Enhanced Magnetic Resonance Imaging of the Kidney Using Iterative Reconstruction and Continuous Golden-Angle Radial Sampling.
Investigative radiology.
2016 11; 51(11):714-719. doi:
10.1097/rli.0000000000000299. [PMID: 27299581] - Eric Lancelot. Revisiting the Pharmacokinetic Profiles of Gadolinium-Based Contrast Agents: Differences in Long-Term Biodistribution and Excretion.
Investigative radiology.
2016 11; 51(11):691-700. doi:
10.1097/rli.0000000000000280. [PMID: 27175546] - Andrea Claudia Bekner Silva Fernandes, Raíssa Bocchi Pedroso, Tatiane França Perles de Mello, Lucélia Donatti, Eneide Aparecida Sabaini Venazzi, Izabel Galhardo Demarchi, Sandra Mara Alessi Aristides, Maria Valdrinez Campana Lonardoni, Thaís Gomes Verzignassi Silveira. In vitro characterization of Leishmania (Viannia) braziliensis isolates from patients with different responses to Glucantime(®) treatment from Northwest Paraná, Brazil.
Experimental parasitology.
2016 Aug; 167(?):83-93. doi:
10.1016/j.exppara.2016.05.003. [PMID: 27181585] - Octavia Bane, Mathilde Wagner, Jeff L Zhang, Hadrien A Dyvorne, Matthew Orton, Henry Rusinek, Bachir Taouli. Assessment of renal function using intravoxel incoherent motion diffusion-weighted imaging and dynamic contrast-enhanced MRI.
Journal of magnetic resonance imaging : JMRI.
2016 08; 44(2):317-26. doi:
10.1002/jmri.25171. [PMID: 26855407] - Farnaz Kheirandish, Bahram Delfan, Hossein Mahmoudvand, Nasim Moradi, Behrouz Ezatpour, Farzad Ebrahimzadeh, Marzieh Rashidipour. Antileishmanial, antioxidant, and cytotoxic activities of Quercus infectoria Olivier extract.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2016 Aug; 82(?):208-15. doi:
10.1016/j.biopha.2016.04.040. [PMID: 27470357] - Nozomu Murata, Luis F Gonzalez-Cuyar, Kiyoko Murata, Corinne Fligner, Russell Dills, Daniel Hippe, Kenneth R Maravilla. Macrocyclic and Other Non-Group 1 Gadolinium Contrast Agents Deposit Low Levels of Gadolinium in Brain and Bone Tissue: Preliminary Results From 9 Patients With Normal Renal Function.
Investigative radiology.
2016 07; 51(7):447-53. doi:
10.1097/rli.0000000000000252. [PMID: 26863577] - Anil N Shetty, Robia Pautler, Ketan Ghaghada, David Rendon, Haijun Gao, Zbigniew Starosolski, Rohan Bhavane, Chandreshkumar Patel, Ananth Annapragada, Chandrasekhar Yallampalli, Wesley Lee. A liposomal Gd contrast agent does not cross the mouse placental barrier.
Scientific reports.
2016 06; 6(?):27863. doi:
10.1038/srep27863. [PMID: 27298076] - Luc Beuzit, Pierre-Antoine Eliat, Vanessa Brun, Jean-Christophe Ferré, Yves Gandon, Elise Bannier, Hervé Saint-Jalmes. Dynamic contrast-enhanced MRI: Study of inter-software accuracy and reproducibility using simulated and clinical data.
Journal of magnetic resonance imaging : JMRI.
2016 06; 43(6):1288-300. doi:
10.1002/jmri.25101. [PMID: 26687041] - Hyun Ryoung Kim, Dong Gil You, Sang-Jun Park, Kyu-Sil Choi, Wooram Um, Jae-Hun Kim, Jae Hyung Park, Young-Sun Kim. MRI Monitoring of Tumor-Selective Anticancer Drug Delivery with Stable Thermosensitive Liposomes Triggered by High-Intensity Focused Ultrasound.
Molecular pharmaceutics.
2016 05; 13(5):1528-39. doi:
10.1021/acs.molpharmaceut.6b00013. [PMID: 26998616] - Sung Yoon Park, Young Taik Oh, Dae Chul Jung. Differentiation between borderline and benign ovarian tumors: combined analysis of MRI with tumor markers for large cystic masses (≥5 cm).
Acta radiologica (Stockholm, Sweden : 1987).
2016 May; 57(5):633-9. doi:
10.1177/0284185115597266. [PMID: 26231948] - Suelen S da Silva, Sandra S Mizokami, Jacqueline R Fanti, Milena M Miranda, Natalia Y Kawakami, Fernanda Humel Teixeira, Eduardo J A Araújo, Carolina Panis, Maria A E Watanabe, José M Sforcin, Wander R Pavanelli, Waldiceu A Verri, Ionice Felipe, Ivete Conchon-Costa. Propolis reduces Leishmania amazonensis-induced inflammation in the liver of BALB/c mice.
Parasitology research.
2016 Apr; 115(4):1557-66. doi:
10.1007/s00436-015-4890-4. [PMID: 26711452] - Daniela Proverbio, Eva Spada, Roberta Perego, Giada Bagnagatti de Giorgi. Seizures as a Consequence of Hyperviscosity Syndrome in Two Dogs Naturally Infected with Leishmania infantum.
Journal of the American Animal Hospital Association.
2016 Mar; 52(2):119-23. doi:
10.5326/jaaha-ms-6240. [PMID: 26808431] - Dayane Priscilla de Souza Queiroz, Carlos Alexandre Carollo, Mônica Cristina Toffoli Kadri, Yasmin Silva Rizk, Vanessa Carneiro Pereira de Araujo, Paulo Eduardo de Oliveira Monteiro, Patrik Oening Rodrigues, Elisa Teruya Oshiro, Maria de Fátima Cepa Matos, Carla Cardozo Pinto de Arruda. In vivo antileishmanial activity and chemical profile of polar extract from Selaginella sellowii.
Memorias do Instituto Oswaldo Cruz.
2016 Mar; 111(3):147-54. doi:
10.1590/0074-02760150307. [PMID: 26910353] - Philippe Robert, Xavier Violas, Sylvie Grand, Stéphane Lehericy, Jean-Marc Idée, Sébastien Ballet, Claire Corot. Linear Gadolinium-Based Contrast Agents Are Associated With Brain Gadolinium Retention in Healthy Rats.
Investigative radiology.
2016 Feb; 51(2):73-82. doi:
10.1097/rli.0000000000000241. [PMID: 26606549] - Juliane S Lanza, Flaviana R Fernandes, José D Corrêa-Júnior, José Mc Vilela, Rogério Magalhães-Paniago, Lucas Am Ferreira, Margareth S Andrade, Cynthia Demicheli, Maria N Melo, Frédéric Frézard. Polarity-sensitive nanocarrier for oral delivery of Sb(V) and treatment of cutaneous leishmaniasis.
International journal of nanomedicine.
2016; 11(?):2305-18. doi:
10.2147/ijn.s105952. [PMID: 27307731] - G A Livanov, A N Lodyagin, B V Batotsyrenov, A T Loladze, S I Glushkov, A L Kovalenko. [The use of reamberin in combined intensive care of acute poisoning].
Klinicheskaia meditsina.
2016 ; 94(5):339-46. doi:
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Eksperimental'naia i klinicheskaia farmakologiia.
2016 ; 79(12):18-23. doi:
NULL. [PMID: 29791098] - I S Chistyakov, A P Medvedev, V V Pichugin. [Optimization of postoperative medical therapy of infective endocarditis in patients with congenital valvular heart disease].
Khirurgiia.
2016; ?(3):51-55. doi:
10.17116/hirurgia2016351-55. [PMID: 27070876] - Somayeh Bahrami, Saleh Esmaeilzadeh, Mehdi Zarei, Fatemeh Ahmadi. Potential application of nanochitosan film as a therapeutic agent against cutaneous leishmaniasis caused by L. major.
Parasitology research.
2015 Dec; 114(12):4617-24. doi:
10.1007/s00436-015-4707-5. [PMID: 26346452] - Hervé Giorgi, Jennifer Ammerman, Jean-Paul Briffaux, Nathalie Fretellier, Claire Corot, Philippe Bourrinet. Non-clinical safety assessment of gadoterate meglumine (Dotarem(®)) in neonatal and juvenile rats.
Regulatory toxicology and pharmacology : RTP.
2015 Dec; 73(3):960-70. doi:
10.1016/j.yrtph.2015.09.018. [PMID: 26382613] - Guenther Schneider, Thorsten Probst, Miles A Kirchin, Jonas Stroeder, Peter Fries, Arno Buecker. Low-dose gadobenate dimeglumine-enhanced MRI of the kidney for the differential diagnosis of localized renal lesions.
La Radiologia medica.
2015 Dec; 120(12):1100-11. doi:
10.1007/s11547-015-0548-7. [PMID: 26088468] - Peter S N Rowe, Lesya V Zelenchuk, Jennifer S Laurence, Phil Lee, William M Brooks, Ellen T McCarthy. Do ASARM peptides play a role in nephrogenic systemic fibrosis?.
American journal of physiology. Renal physiology.
2015 Nov; 309(9):F764-9. doi:
10.1152/ajprenal.00201.2015. [PMID: 26336161] - Katherine M Shaffer, Mehul R Parikh, Thomas M Runge, Sebastian D Perez, Sonali S Sakaria, Ram M Subramanian. Renal safety of intravenous gadolinium-enhanced magnetic resonance imaging in patients awaiting liver transplantation.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society.
2015 Nov; 21(11):1340-6. doi:
10.1002/lt.24118. [PMID: 25786913] - I V Zadnipryanyi, O S Tretyakova, T P Sataeva. [Investigation of the antioxidant activity and cardioprotective effect of reamberin and cytoflavin in newborn rats exposed to chronic hemic hypoxia].
Arkhiv patologii.
2015 Nov; 77(6):39-44. doi:
10.17116/patol201577639-44. [PMID: 26841648]