Epicatechin (BioDeep_00000000020)

 

Secondary id: BioDeep_00000000763, BioDeep_00000338337, BioDeep_00000398019, BioDeep_00000410524, BioDeep_00000621567, BioDeep_00000859356

natural product human metabolite PANOMIX_OTCML-2023 blood metabolite BioNovoGene_Lab2019


代谢物信息卡片


(2R,3R)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3,5,7-triol

化学式: C15H14O6 (290.0790344)
中文名称: (-)-表儿茶素, 表儿茶素
谱图信息: 最多检出来源 Homo sapiens(blood) 43.66%

Reviewed

Last reviewed on 2024-07-09.

Cite this Page

Epicatechin. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China. https://query.biodeep.cn/s/epicatechin (retrieved 2024-12-05) (BioDeep RN: BioDeep_00000000020). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

分子结构信息

SMILES: c1(cc(c2c(c1)O[C@@H]([C@@H](C2)O)c1cc(c(cc1)O)O)O)O
InChI: InChI=1/C15H14O6/c16-8-4-11(18)9-6-13(20)15(21-14(9)5-8)7-1-2-10(17)12(19)3-7/h1-5,13,15-20H,6H2/t13-,15-/m1/s1

描述信息

Epicatechin is an antioxidant flavonoid, occurring especially in woody plants as both (+)-catechin and (-)-epicatechin (cis) forms. Catechin is a tannin peculiar to green and white tea because the black tea oxidation process reduces catechins in black tea. Catechin is a powerful, water soluble polyphenol and antioxidant that is easily oxidized. Several thousand types are available in the plant world. As many as two thousand are known to have a flavon structure and are called flavonoids. Catechin is one of them. Green tea is manufactured from fresh, unfermented tea leaves; the oxidation of catechins is minimal, and hence they are able to serve as antioxidants. Researchers believe that catechin is effective because it easily sticks to proteins, blocking bacteria from adhering to cell walls and disrupting their ability to destroy them. Viruses have hooks on their surfaces and can attach to cell walls. The catechin in green tea prevents viruses from adhering and causing harm. Catechin reacts with toxins created by harmful bacteria (many of which belong to the protein family) and harmful metals such as lead, mercury, chrome, and cadmium. From its NMR espectra, there is a doubt on 2 and 3 atoms configuration. It seems to be that they are in trans position.
Epicatechin, also known as (+)-cyanidanol-3 or 2,3-cis-epicatechin, is a member of the class of compounds known as catechins. Catechins are compounds containing a catechin moiety, which is a 3,4-dihydro-2-chromene-3,5.7-tiol. Thus, epicatechin is considered to be a flavonoid lipid molecule. Epicatechin is practically insoluble (in water) and a very weakly acidic compound (based on its pKa). Epicatechin can be found in cashew nut, which makes epicatechin a potential biomarker for the consumption of this food product. Epicatechin can be found primarily in blood, feces, and urine, as well as throughout most human tissues. Epicatechin is a flavan-3-ol, a type of natural phenol and antioxidant. It is a plant secondary metabolite. It belongs to the group of flavan-3-ols (or simply flavanols), part of the chemical family of flavonoids .
(-)-epicatechin is a catechin with (2R,3R)-configuration. It has a role as an antioxidant. It is a polyphenol and a catechin. It is an enantiomer of a (+)-epicatechin.
Epicatechin has been used in trials studying the treatment of Pre-diabetes.
(-)-Epicatechin is a natural product found in Visnea mocanera, Litsea rotundifolia, and other organisms with data available.
An antioxidant flavonoid, occurring especially in woody plants as both (+)-catechin and (-)-epicatechin (cis) forms.
See also: Crofelemer (monomer of); Bilberry (part of); Cats Claw (part of) ... View More ...
A catechin with (2R,3R)-configuration.

[Raw Data] CB030_(-)-Epicatechin_pos_20eV_CB000016.txt
[Raw Data] CB030_(-)-Epicatechin_pos_50eV_CB000016.txt
[Raw Data] CB030_(-)-Epicatechin_pos_40eV_CB000016.txt
[Raw Data] CB030_(-)-Epicatechin_pos_10eV_CB000016.txt
[Raw Data] CB030_(-)-Epicatechin_pos_30eV_CB000016.txt
[Raw Data] CB030_(-)-Epicatechin_neg_50eV_000009.txt
[Raw Data] CB030_(-)-Epicatechin_neg_30eV_000009.txt
[Raw Data] CB030_(-)-Epicatechin_neg_10eV_000009.txt
[Raw Data] CB030_(-)-Epicatechin_neg_40eV_000009.txt
[Raw Data] CB030_(-)-Epicatechin_neg_20eV_000009.txt

Epicatechin. CAS Common Chemistry. CAS, a division of the American Chemical Society, n.d. https://commonchemistry.cas.org/detail?cas_rn=490-46-0 (retrieved 2024-07-09) (CAS RN: 490-46-0). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).
(-)-Epicatechin inhibits cyclooxygenase-1 (COX-1) with an IC50 of 3.2 μM. (-)-Epicatechin inhibits the IL-1β-induced expression of iNOS by blocking the nuclear localization of the p65 subunit of NF-κB.
(-)-Epicatechin inhibits cyclooxygenase-1 (COX-1) with an IC50 of 3.2 μM. (-)-Epicatechin inhibits the IL-1β-induced expression of iNOS by blocking the nuclear localization of the p65 subunit of NF-κB.
(-)-Epicatechin inhibits cyclooxygenase-1 (COX-1) with an IC50 of 3.2 μM. (-)-Epicatechin inhibits the IL-1β-induced expression of iNOS by blocking the nuclear localization of the p65 subunit of NF-κB.
(-)-Epicatechin inhibits cyclooxygenase-1 (COX-1) with an IC50 of 3.2 μM. (-)-Epicatechin inhibits the IL-1β-induced expression of iNOS by blocking the nuclear localization of the p65 subunit of NF-κB.

同义名列表

94 个代谢物同义名

2-(3,4-dihydroxyphenyl)-2,3,4-trihydro-3,5,7-trihydroxychromene; (-)-EPICATECHIN(EG) (CONSTITUENT OF POWDERED DECAFFEINATED GREEN TEA EXTRACT); 2H-1-Benzopyran-3,5,7-triol, 2-(3,4-dihydroxyphenyl)-3,4-dihydro-, (2R-cis)-; 2H-1-Benzopyran-3,5,7-triol, 2-(3,4-dihydroxyphenyl)-3,4-dihydro-, (2R,3R)-; 2H-1-Benzopyran-3,5,7-triol, 2-(3,4-dihydroxyphenyl)-3,4-dihydro-,(2R,3R)-; (-)-EPICATECHIN (CONSTITUENT OF GRAPE SEEDS OLIGOMERIC PROANTHOCYANIDINS); (2R-cis)-2-(3,4-Dihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3,5,7-triol; (2R,3R)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3,5,7-triol; (2R,3R)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-2H-chromene-3,5,7-triol; 2-(3,4-Dihydroxyphenyl)-2,3,4-trihydro-3,5,7-trihydroxychromene; Epicatechin, primary pharmaceutical reference standard; (-)-EPICATECHIN (CONSTITUENT OF MARITIME PINE) [DSC]; (2R,3R)-2-(3,4-dihydroxyphenyl)chromane-3,5,7-triol; (2R,3R)-2-(3,4-Dihydroxyphenyl)-3,5,7-chromanetriol; (2R,3R)-2-(3,4-Dihydroxyphenyl)chroman-3,5,7-triol; (-)-EPICATECHIN (CONSTITUENT OF MARITIME PINE); (-)-Epicatechin, >=98\\% (HPLC), from green tea; (-)-(2R:3R)-5,7,3,4-Tetrahydroxyflavan-3-ol; (-)-cis-3,3,4,5,7-Pentahydroxyflavane; (-)-Epicatechin, analytical standard; CF3BA0C2-DE1B-44AB-A4D3-800F017221BA; (-)-Epicatechin, >=90\\% (HPLC); 3,3,4,5,7-Pentahydroxyflavane; (-)-EPICATECHIN (USP-RS); (-)-EPICATECHIN [USP-RS]; (2R,3R)-(-)-Epicatechin; 3,3,4,5,7-Flavanpentol; L-EPICATECHIN [WHO-DD]; (-)-cis-Epicatechin; 2,3-cis-epicatechin; L-Epicatechin ,(S); Epicatechol, (-)-; Spectrum2_000675; Epigallocatechin; BCBcMAP01_000224; L(-)-Epicatechin; Spectrum5_000929; Spectrum3_000243; (+)-Cyanidanol-3; .alpha. Catechin; (-)-epi catechin; Spectrum4_000949; Acid, catechinic; Acid, catechuic; ent-Epicatechin; (-)-Epicatechol; Catechinic Acid; Epicatechin-(-); UNII-34PHS7TU43; (-)-Epicatechin; Tox21_110101_1; (+)-Cyanidanol; alpha-catechin; (-)epicatechin; Catechuic Acid; l-Acacatechin; Teacatechin I; Oprea1_209947; L-Epicatechin; DivK1c_006363; l-Epicatechol; Tox21_110101; (+)-Catechin; epi-Catechin; ACon1_001106; Cyanidanol 3; Cyanidanol-3; KBio2_000639; epi-Catechol; KBio2_005775; KBio3_001126; KBio2_003207; KBio1_001307; Acacatechin; SMP1_000115; Epicatechin; Epicatechol; Cianidanol; KSC-10-144; 34PHS7TU43; Catechin; Catergen; CHEBI:90; Colatein; C15H14O6; Kakaol; KB-53; KB 53; Zyma; KB53; 28E; (-)-3 3 4 5 7-Pentahydroxyflavan; L-Epicatechin; (-)-Epicatechin



数据库引用编号

48 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(2)

PlantCyc(3)

代谢反应

41 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(3)

WikiPathways(1)

Plant Reactome(0)

INOH(0)

PlantCyc(36)

COVID-19 Disease Map(0)

PathBank(1)

PharmGKB(0)

449 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Lihui Xiang, Chen Zhu, Jiajia Qian, Xiaochen Zhou, Miao Wang, Zhenshuo Song, Changsong Chen, Wenquan Yu, Lin Chen, Lanting Zeng. Positive contributions of the stem to the formation of white tea quality-related metabolites during withering. Food chemistry. 2024 Aug; 449(?):139173. doi: 10.1016/j.foodchem.2024.139173. [PMID: 38593722]
  • Lin Chen, Jingyi Wang, Yijun Yang, Huajie Wang, Anan Xu, Junhui Ma, Yuefei Wang, Ping Xu. Identifying the temporal contributors and their interactions during dynamic formation of black tea cream. Food chemistry. 2024 Aug; 448(?):139138. doi: 10.1016/j.foodchem.2024.139138. [PMID: 38569407]
  • Xiujuan Chen, Yongyong Wang, Yue Chen, Jun Dai, Shuiyuan Cheng, Xiaoqiang Chen. Formation, physicochemical properties, and biological activities of theabrownins. Food chemistry. 2024 Aug; 448(?):139140. doi: 10.1016/j.foodchem.2024.139140. [PMID: 38574720]
  • Zhi-Quan Li, Xiao-Li Yin, Hui-Wen Gu, Zhi-Xin Peng, Baomiao Ding, Zhenshun Li, Ying Chen, Wanjun Long, Haiyan Fu, Yuanbin She. Discrimination and prediction of Qingzhuan tea storage year using quantitative chemical profile combined with multivariate analysis: Advantages of MRMHR based targeted quantification metabolomics. Food chemistry. 2024 Aug; 448(?):139088. doi: 10.1016/j.foodchem.2024.139088. [PMID: 38547707]
  • Mingyu Pan, Wenfeng Geng, Yuanxiao Wang, Makoto Tsunoda, Jiatong Liu, Yingxia Zhang, Haimei Yang, Lu-Shuang Li, Shiwen Song, Jinqiang Liang, Yanting Song. Simultaneous determination of five constituents of areca nut extract in rat plasma using UPLC-MS/MS and its application in a pharmacokinetic study. Journal of pharmaceutical and biomedical analysis. 2024 Aug; 245(?):116158. doi: 10.1016/j.jpba.2024.116158. [PMID: 38643703]
  • Hongzhe Zeng, Changwei Liu, Liwei Wan, Liyuan Peng, Shuai Wen, Wenwen Fang, Hongyu Chen, Kuofei Wang, Xiaomei Yang, Jian'an Huang, Zhonghua Liu. (-)-Epicatechin ameliorates type 2 diabetes mellitus by reshaping the gut microbiota and Gut-Liver axis in GK rats. Food chemistry. 2024 Jul; 447(?):138916. doi: 10.1016/j.foodchem.2024.138916. [PMID: 38461723]
  • Jiao Feng, Jiayun Zhuang, Qianlian Chen, Hongzheng Lin, Qiang Chu, Ping Chen, Fang Wang, Bugui Yu, Zhilong Hao. The effect of maturity of tea leaves and processing methods on the formation of milky flavor in white tea - A metabolomic study. Food chemistry. 2024 Jul; 447(?):139080. doi: 10.1016/j.foodchem.2024.139080. [PMID: 38520904]
  • He Peng, Xiaojian Lin, Ying Wang, Jiajun Chen, Qian Zhao, Shengjia Chen, Qi Cheng, Chaojie Chen, Tingting Sang, Hongyu Zhou, Jun Xiao, Wen Wang, Liu Fang, Xingya Wang. Epigallocatechin gallate suppresses mitotic clonal expansion and adipogenic differentiation of preadipocytes through impeding JAK2/STAT3-mediated transcriptional cascades. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2024 Jul; 129(?):155563. doi: 10.1016/j.phymed.2024.155563. [PMID: 38552377]
  • Li He, Lisheng Peng, Lianan Wang, Xiaoyan Jiang, Xinfeng Sun, Haiwen Li, Tong Lin, Zhulin Wu, Sen Lin. Investigation of folate-modified EGCG-loaded thermosensitive nanospheres inducing immunogenic cell death and damage-associated molecular patterns in hepatocellular carcinoma. Biochemical and biophysical research communications. 2024 Jun; 714(?):149976. doi: 10.1016/j.bbrc.2024.149976. [PMID: 38677007]
  • Xiang Dong, Wenying Li, Changzhu Li, Otobong Donald Akan, Chancan Liao, Jie Cao, Lin Zhang. Integrated transcriptomics and metabolomics revealed the mechanism of catechin biosynthesis in response to lead stress in tung tree (Vernicia fordii). The Science of the total environment. 2024 Jun; 930(?):172796. doi: 10.1016/j.scitotenv.2024.172796. [PMID: 38692325]
  • Serhat Kocer, Omer Utku Copur, Canan Ece Tamer, Senem Suna, Seda Kayahan, Erdinc Uysal, Semra Cavus, Ozgur Akman. Optimization and characterization of chestnut shell pigment extract obtained microwave assisted extraction by response surface methodology. Food chemistry. 2024 Jun; 443(?):138424. doi: 10.1016/j.foodchem.2024.138424. [PMID: 38301551]
  • Jingwen Xu, Hezhen Zhang, Mengyu Deng, Haotong Guo, Lifan Cui, Zhengqin Liu, Jing Xu. Formation mechanism of quinoa protein hydrolysate-EGCG complexes at different pH conditions and its effect on the protein hydrolysate-lipid co-oxidation in emulsions. Food research international (Ottawa, Ont.). 2024 Jun; 186(?):114365. doi: 10.1016/j.foodres.2024.114365. [PMID: 38729700]
  • Feng Wei, Delin Li, Xiaodong Chen, Yubing Li, Yuting Zeng, Yilin Cai, Youtao Zeng, Yu Chen, Xiao Ma, Jinhao Zeng. Therapeutic effects of epigallocatechin-3-gallate for inflammatory bowel disease: A preclinical meta-analysis. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2024 Jun; 128(?):155408. doi: 10.1016/j.phymed.2024.155408. [PMID: 38503153]
  • Asako Narai-Kanayama, Sumio Hayakawa, Takayuki Yoshino, Futa Honda, Hiroko Matsuda, Yumiko Oishi. Differential effects of theasinensins and epigallocatechin-3-O-gallate on phospholipid bilayer structure and liposomal aggregation. Biochimica et biophysica acta. Biomembranes. 2024 Jun; 1866(5):184312. doi: 10.1016/j.bbamem.2024.184312. [PMID: 38579959]
  • Jiayan Zeng, Yanmin Weng, Tianli Lai, Lan Chen, Ying Li, Qiqi Huang, Saiyi Zhong, Shibiao Wan, Lianxiang Luo. Procyanidin alleviates ferroptosis and inflammation of LPS-induced RAW264.7 cell via the Nrf2/HO-1 pathway. Naunyn-Schmiedeberg's archives of pharmacology. 2024 Jun; 397(6):4055-4067. doi: 10.1007/s00210-023-02854-2. [PMID: 38010399]
  • Lu Lu, Lu Wang, Ruyi Liu, Yingbin Zhang, Xinqiang Zheng, Jianliang Lu, Xinchao Wang, Jianhui Ye. An efficient artificial intelligence algorithm for predicting the sensory quality of green and black teas based on the key chemical indices. Food chemistry. 2024 May; 441(?):138341. doi: 10.1016/j.foodchem.2023.138341. [PMID: 38176147]
  • Ziqiong Zhou, Yan Li, Fangyuan Wang, Guanghao Zhu, Shenglan Qi, Haonan Wang, Yuhe Ma, Rong Zhu, Yuejuan Zheng, Guangbo Ge, Ping Wang. Bioactive components and mechanisms of Pu-erh tea in improving levodopa metabolism in rats through COMT inhibition. Food & function. 2024 May; 15(10):5287-5299. doi: 10.1039/d4fo00538d. [PMID: 38639730]
  • Xiwen Zhang, Zhihao Huo, Xiaotong Jia, Yuanyuan Xiong, Baohua Li, Liangyou Zhang, Xin Li, Xianhong Li, Yinrui Fang, Xin Dong, Gangyi Chen. (+)-Catechin ameliorates diabetic nephropathy injury by inhibiting endoplasmic reticulum stress-related NLRP3-mediated inflammation. Food & function. 2024 May; 15(10):5450-5465. doi: 10.1039/d3fo05400d. [PMID: 38687305]
  • Karolina Jafernik, Paweł Kubica, Marta Sharafan, Aleksandra Kruk, Magdalena Anna Malinowska, Sebastian Granica, Agnieszka Szopa. Phenolic compound profiling and antioxidant potential of different types of Schisandra henryi in vitro cultures. Applied microbiology and biotechnology. 2024 May; 108(1):322. doi: 10.1007/s00253-024-13159-6. [PMID: 38713216]
  • Jilai Cui, Bin Wu, Jie Zhou. Changes in amino acids, catechins and alkaloids during the storage of oolong tea and their relationship with antibacterial effect. Scientific reports. 2024 05; 14(1):10424. doi: 10.1038/s41598-024-60951-5. [PMID: 38710752]
  • Adam J Lewis, Amanda C Richards, Alejandra A Mendez, Bijaya K Dhakal, Tiffani A Jones, Jamie L Sundsbak, Danelle S Eto, Alexis A Rousek, Matthew A Mulvey. Plant phenolics inhibit focal adhesion kinase and suppress host cell invasion by uropathogenic Escherichia coli. Infection and immunity. 2024 May; 92(5):e0008024. doi: 10.1128/iai.00080-24. [PMID: 38534100]
  • Zhaoxian Zhang, Yaoyi Jia, Chenghui Zhang, Zikang Zhang, Fangsha Jin, Dandan Pan, Daxiang Li, Xiangwei Wu. Efficacy of epigallocatechin gallate (EGCG) and its underlying mechanism in preventing bisphenol-A-induced metabolic disorders in mice. Journal of hazardous materials. 2024 May; 469(?):134098. doi: 10.1016/j.jhazmat.2024.134098. [PMID: 38522198]
  • Wei Hu, Mingchun Wen, Zisheng Han, Xue-Ling Gao, Jia-Ping Ke, Mengting Zhu, Xinlin Wei, Yong Cheng, Xiaochun Wan, Yundong Shao, Liang Zhang. Revealing the variances in color formation and bioactivities of seven catechin monomers throughout the enzymatic reaction by colorimetric and mass spectrometry. Food research international (Ottawa, Ont.). 2024 May; 184(?):114266. doi: 10.1016/j.foodres.2024.114266. [PMID: 38609242]
  • Pingping Wang, Xianghua Chai, Chun Chen, Xuejuan Duan, Kegang Wu, Xiong Fu. Enhanced in vitro bioavailability of resveratrol-loaded emulsion stabilized by β-lactoglobulin-catechin with excellent antioxidant activity. International journal of biological macromolecules. 2024 May; 267(Pt 1):131304. doi: 10.1016/j.ijbiomac.2024.131304. [PMID: 38569999]
  • Viviana Teresa Orlandi, Fabrizio Bolognese, Luca Chiodaroli, Ilaria Armenia, Enrico Caruso, Miryam Chiara Malacarne. Antibiofilm Activity of Combretum micranthum G. Don Catechin-Sugar Phytocomplex on Pseudomonas aeruginosa. Molecules (Basel, Switzerland). 2024 May; 29(9):. doi: 10.3390/molecules29092091. [PMID: 38731582]
  • Jian Zhao, Zhongling Chen, Lingxi Li, Baoshan Sun. UHPLC-MS/MS analysis and protective effects on neurodegenerative diseases of phenolic compounds in different parts of Diospyros kaki L. cv. Mopan. Food research international (Ottawa, Ont.). 2024 May; 184(?):114251. doi: 10.1016/j.foodres.2024.114251. [PMID: 38609229]
  • Zihao Qiu, Jinmei Liao, Jiahao Chen, Ansheng Li, Minyao Lin, Hongmei Liu, Wei Huang, Binmei Sun, Jing Liu, Shaoqun Liu, Peng Zheng. Comprehensive analysis of fresh tea (Camellia sinensis cv. Lingtou Dancong) leaf quality under different nitrogen fertilization regimes. Food chemistry. 2024 May; 439(?):138127. doi: 10.1016/j.foodchem.2023.138127. [PMID: 38064834]
  • Tie Hu, Fa-Jia Hu, Huang Huang, Ze-Yu Zhang, Ya-Mei Qiao, Wen-Xiong Huang, Yi-Cheng Wang, Xin-Yi Tang, Song-Qing Lai. Epigallocatechin-3-gallate confers protection against myocardial ischemia/reperfusion injury by inhibiting ferroptosis, apoptosis, and autophagy via modulation of 14-3-3η. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2024 May; 174(?):116542. doi: 10.1016/j.biopha.2024.116542. [PMID: 38574620]
  • Yong Chen, Chen Xie, Yining Lei, Dan Ye, Le Wang, Fang Xiong, Hui Wu, Qiang He, Hongfu Zhou, Ling Li, Jun Xing, Cai Wang, Min Zheng. Theabrownin from Qingzhuan tea prevents high-fat diet-induced MASLD via regulating intestinal microbiota. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2024 May; 174(?):116582. doi: 10.1016/j.biopha.2024.116582. [PMID: 38642504]
  • Zhongting Lu, Yan Zheng, Juan Zheng, Qijian Liang, Qingcai Zhen, Mengjie Cui, Haoru Yang, Haotian Wu, Cuixia Tian, Kangming Zhu, Chunyong Bian, Lei Du, Hao Wu, Xin Guo. Theabrownin from Fu Brick tea ameliorates high-fat induced insulin resistance, hepatic steatosis, and inflammation in mice by altering the composition and metabolites of gut microbiota. Food & function. 2024 Apr; 15(8):4421-4435. doi: 10.1039/d3fo05459d. [PMID: 38563324]
  • Zhiyuan Lin, Weidong Dai, Shanshan Hu, Dan Chen, Han Yan, Liang Zeng, Zhi Lin. Stored white tea ameliorates DSS-induced ulcerative colitis in mice by modulating the composition of the gut microbiota and intestinal metabolites. Food & function. 2024 Apr; 15(8):4262-4275. doi: 10.1039/d3fo05176e. [PMID: 38526548]
  • Yue Xiao, Dongmei Yang, Haoran Zhang, Huan Guo, Ying Liao, Changhong Lian, Yuqin Yao, Hong Gao, Yina Huang. Theabrownin as a Potential Prebiotic Compound Regulates Lipid Metabolism via the Gut Microbiota, Microbiota-Derived Metabolites, and Hepatic FoxO/PPAR Signaling Pathways. Journal of agricultural and food chemistry. 2024 Apr; 72(15):8506-8520. doi: 10.1021/acs.jafc.3c08541. [PMID: 38567990]
  • Sapna I, A Jayadeep. Enzyme-treated red rice (Oryza sativa L.) bran extracts mitigate inflammatory markers in RAW 264.7 macrophage cells and exhibit anti-inflammatory efficacy greater/comparable to ferulic acid, catechin, γ-tocopherol, and γ-oryzanol. Journal of ethnopharmacology. 2024 Apr; 323(?):117616. doi: 10.1016/j.jep.2023.117616. [PMID: 38142877]
  • Vinícius de C Oliveira, Sarah de O Rodrigues, Sabrinna M T Souto, Geraldo A da Silva, Wagner Vilegas, Bárbara Garcia Ferri, Ahmed M El-Gazzar, Gaber El-Saber Batiha, Mohamed H Mahmoud, Marcelo J D Silva, Jorge P Pagnossa, Marcelo A da Silva. Chemical profile and evaluation of the pharmacological activity of the dry extract and fraction of ethyl acetate obtained from the leaves of Mimosa caesalpiniifolia. Journal of ethnopharmacology. 2024 Apr; 323(?):117716. doi: 10.1016/j.jep.2024.117716. [PMID: 38190955]
  • Min Zeng, Joanna K Hodges, Avinash Pokala, Mona Khalafi, Geoffrey Y Sasaki, Jillian Pierson, Sisi Cao, Guy Brock, Zhongtang Yu, Jiangjiang Zhu, Yael Vodovotz, Richard S Bruno. A green tea extract confection decreases circulating endotoxin and fasting glucose by improving gut barrier function but without affecting systemic inflammation: A double-blind, placebo-controlled randomized trial in healthy adults and adults with metabolic syndrome. Nutrition research (New York, N.Y.). 2024 Apr; 124(?):94-110. doi: 10.1016/j.nutres.2024.02.001. [PMID: 38430822]
  • Zhi-Wei Ren, Hong-Jing Pan, Cheng Hu, Miao-Miao Le, Yan-Hua Long, Qian Xu, Zhong-Wen Xie, Tie-Jun Ling. Rolling forms the diversities of small molecular nonvolatile metabolite profile and consequently shapes the bacterial community structure for Keemun black tea. Food research international (Ottawa, Ont.). 2024 Apr; 181(?):114094. doi: 10.1016/j.foodres.2024.114094. [PMID: 38448096]
  • Chenlu Ma, Youfa Xie, Xin Huang, Lu Zhang, David Julian McClements, Liqiang Zou, Wei Liu. Encapsulation of (-)-epigallocatechin gallate (EGCG) within phospholipid-based nanovesicles using W/O emulsion-transfer methods: Masking bitterness and delaying release of EGCG. Food chemistry. 2024 Mar; 437(Pt 2):137913. doi: 10.1016/j.foodchem.2023.137913. [PMID: 37939421]
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