4-amino-4-deoxychorismate (BioDeep_00000008621)
Secondary id: BioDeep_00001872485
human metabolite
代谢物信息卡片
化学式: C10H11NO5 (225.0637196)
中文名称:
谱图信息:
最多检出来源 Homo sapiens(blood) 0.11%
分子结构信息
SMILES: C1=C[C@H]([C@@H](C=C1C(=O)O)OC(=C)C(=O)O)N
InChI: InChI=1S/C10H11NO5/c1-5(9(12)13)16-8-4-6(10(14)15)2-3-7(8)11/h2-4,7-8H,1,11H2,(H,12,13)(H,14,15)/t7-,8-/m1/s1
描述信息
4-amino-4-deoxychorismate, also known as adc, belongs to dicarboxylic acids and derivatives class of compounds. Those are organic compounds containing exactly two carboxylic acid groups. 4-amino-4-deoxychorismate is soluble (in water) and a weakly acidic compound (based on its pKa). 4-amino-4-deoxychorismate can be found in a number of food items such as chives, narrowleaf cattail, green vegetables, and chicory leaves, which makes 4-amino-4-deoxychorismate a potential biomarker for the consumption of these food products. 4-amino-4-deoxychorismate exists in E.coli (prokaryote) and yeast (eukaryote).
同义名列表
数据库引用编号
18 个数据库交叉引用编号
- ChEBI: CHEBI:18198
- ChEBI: CHEBI:35181
- KEGG: C11355
- PubChem: 443142
- PubChem: 116
- HMDB: HMDB0304170
- Metlin: METLIN3363
- MetaCyc: 4-AMINO-4-DEOXYCHORISMATE
- KNApSAcK: C00000730
- foodb: FDB030486
- chemspider: 391414
- CAS: 133442-18-9
- PMhub: MS000022257
- PubChem: 13530
- 3DMET: B04223
- NIKKAJI: J1.639.267G
- RefMet: 4-Amino-4-deoxychorismic acid
- PubChem: 45266632
分类词条
相关代谢途径
Reactome(0)
PlantCyc(0)
代谢反应
5 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(1)
- tetrahydrofolate biosynthesis I:
6-hydroxymethyl-7,8-dihydropterin + ATP ⟶ 6-hydroxymethyl-dihydropterin diphosphate + AMP + H+
WikiPathways(0)
Plant Reactome(4)
- Metabolism and regulation:
ATP + CoA + propionate ⟶ AMP + PPi + PROP-CoA - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - Folate biosynthesis:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Tetrahydrofolate biosynthesis II:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
7 个相关的物种来源信息
- 1886 Streptomyces albidoflavus: 10.1016/0003-9861(89)90300-7
- 1902 Streptomyces coelicolor: 10.1016/0003-9861(89)90300-7
- 7461 Apis cerana: 10.1371/JOURNAL.PONE.0175573
- 1886 Streptomyces albidoflavus: 10.1016/0003-9861(89)90300-7
- 1902 Streptomyces coelicolor: 10.1016/0003-9861(89)90300-7
- 7461 Apis cerana: 10.1371/JOURNAL.PONE.0175573
- 9606 Homo sapiens: -
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Maddalena Rossi, Alberto Amaretti, Stefano Raimondi. Folate production by probiotic bacteria.
Nutrients.
2011 01; 3(1):118-34. doi:
10.3390/nu3010118. [PMID: 22254078] - Javier Botet, Laura Mateos, José L Revuelta, María A Santos. A chemogenomic screening of sulfanilamide-hypersensitive Saccharomyces cerevisiae mutants uncovers ABZ2, the gene encoding a fungal aminodeoxychorismate lyase.
Eukaryotic cell.
2007 Nov; 6(11):2102-11. doi:
10.1128/ec.00266-07. [PMID: 17873082] - Gilles J C Basset, Stéphane Ravanel, Eoin P Quinlivan, Ruth White, James J Giovannoni, Fabrice Rébeillé, Brian P Nichols, Kazuo Shinozaki, Motoaki Seki, Jesse F Gregory, Andrew D Hanson. Folate synthesis in plants: the last step of the p-aminobenzoate branch is catalyzed by a plastidial aminodeoxychorismate lyase.
The Plant journal : for cell and molecular biology.
2004 Nov; 40(4):453-61. doi:
10.1111/j.1365-313x.2004.02231.x. [PMID: 15500462] - A W Mondorf. [Evidence of urinary tubular proteins in inflammatory and toxic kidney damage].
Wiener medizinische Wochenschrift. Supplement.
1975; 27(?):20-3. doi:
NULL. [PMID: 5816]