1-Methylpyrrolinium (BioDeep_00000006075)
Secondary id: BioDeep_00001869573
human metabolite
代谢物信息卡片
1-Methyl-delta(1)-pyrrolinium, 2-(14)C-labeled
化学式: C5H10N1+ (84.08132)
中文名称: 1-甲基-delta(1)-吡咯啉鎓
谱图信息:
最多检出来源 Viridiplantae(plant) 2.08%
分子结构信息
SMILES: C[N+]1=CCCC1
InChI: InChI=1S/C5H10N/c1-6-4-2-3-5-6/h4H,2-3,5H2,1H3/q+1
描述信息
This compound belongs to the family of Pyrrolines. These are compounds containing a pyrroline ring, which is a five-member unsaturated aliphatic ring with one nitrogen atom and four carbon atoms.
同义名列表
数据库引用编号
12 个数据库交叉引用编号
- ChEBI: CHEBI:27435
- KEGG: C06178
- PubChem: 440932
- HMDB: HMDB0060253
- MetaCyc: CPD-7994
- KNApSAcK: C00034612
- CAS: 16032-02-3
- PMhub: MS000019033
- PubChem: 8429
- 3DMET: B00914
- NIKKAJI: J493.544F
- RefMet: 1-Methylpyrrolinium
分类词条
相关代谢途径
Reactome(0)
BioCyc(4)
PlantCyc(7)
- superpathway of hyoscyamine and scopolamine biosynthesis
- hyoscyamine and scopolamine biosynthesis
- superpathway of hyoscyamine (atropine) and scopolamine biosynthesis
- N-methyl-Δ1-pyrrolinium cation biosynthesis
- superpathway of nicotine biosynthesis
- calystegine biosynthesis
- tropane alkaloids biosynthesis
代谢反应
57 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(8)
- nicotine biosynthesis:
H2O + NaMN ⟶ D-ribofuranose 5-phosphate + H+ + nicotinate - superpathway of nicotine biosynthesis:
H2O + NaMN ⟶ D-ribofuranose 5-phosphate + H+ + nicotinate - N-methyl-Δ1-pyrrolinium cation biosynthesis:
N-methylaminobutanal ⟶ H2O + N-methyl-Δ1-pyrrolinium cation - superpathway of hyoscyamine and scopolamine biosynthesis:
(S)-atropinium + 2-oxoglutarate + O2 ⟶ (6S)-hydroxyhyoscyamine + CO2 + succinate - calystegine biosynthesis:
pseudotropine ⟶ an unknown compound - cocaine biosynthesis:
NADP+ + ecgonine methyl ester ⟶ H+ + NADPH + methyl ecgonone - hyoscyamine and scopolamine biosynthesis:
(S)-atropinium + 2-oxoglutarate + O2 ⟶ (6S)-hydroxyhyoscyamine + CO2 + succinate - hyoscyamine and scopolamine biosynthesis:
2-oxoglutarate + L-hyoscyamine + O2 ⟶ (6S)-hydroxyhyoscyamine + CO2 + succinate
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(47)
- hyoscyamine and scopolamine biosynthesis:
(6S)-hydroxyhyoscyamine + 2-oxoglutarate + O2 ⟶ CO2 + H+ + H2O + scopolamine + succinate - superpathway of hyoscyamine and scopolamine biosynthesis:
N-methylputrescine + H2O + O2 ⟶ N-methylaminobutanal + ammonium + hydrogen peroxide - hyoscyamine and scopolamine biosynthesis:
NADP+ + tropine ⟶ H+ + NADPH + tropinone - calystegine biosynthesis:
NADP+ + pseudotropine ⟶ H+ + NADPH + tropinone - superpathway of hyoscyamine and scopolamine biosynthesis:
N-methylputrescine + H2O + O2 ⟶ N-methylaminobutanal + ammonium + hydrogen peroxide - hyoscyamine and scopolamine biosynthesis:
NADP+ + tropine ⟶ H+ + NADPH + tropinone - superpathway of hyoscyamine and scopolamine biosynthesis:
N-methylputrescine + H2O + O2 ⟶ N-methylaminobutanal + ammonium + hydrogen peroxide - hyoscyamine and scopolamine biosynthesis:
(S)-atropine + 2-oxoglutarate + O2 ⟶ (6S)-hydroxyhyoscyamine + CO2 + succinate - superpathway of hyoscyamine and scopolamine biosynthesis:
N-methylputrescine + H2O + O2 ⟶ N-methylaminobutanal + ammonium + hydrogen peroxide - superpathway of hyoscyamine and scopolamine biosynthesis:
NADP+ + tropine ⟶ H+ + NADPH + tropinone - hyoscyamine and scopolamine biosynthesis:
NADP+ + tropine ⟶ H+ + NADPH + tropinone - calystegine biosynthesis:
pseudotropine ⟶ an unknown compound - hyoscyamine and scopolamine biosynthesis:
(S)-atropine + 2-oxoglutarate + O2 ⟶ (6S)-hydroxyhyoscyamine + CO2 + succinate - calystegine biosynthesis:
NADP+ + pseudotropine ⟶ H+ + NADPH + tropinone - superpathway of hyoscyamine and scopolamine biosynthesis:
N-methylputrescine + H2O + O2 ⟶ N-methylaminobutanal + ammonium + hydrogen peroxide - hyoscyamine and scopolamine biosynthesis:
NADP+ + tropine ⟶ H+ + NADPH + tropinone - superpathway of hyoscyamine and scopolamine biosynthesis:
N-methylputrescine + H2O + O2 ⟶ N-methylaminobutanal + ammonium + hydrogen peroxide - superpathway of nicotine biosynthesis:
N-methylputrescine + H2O + O2 ⟶ N-methylaminobutanal + ammonium + hydrogen peroxide - N-methyl-Δ1-pyrrolinium cation biosynthesis:
N-methylputrescine + H2O + O2 ⟶ N-methylaminobutanal + ammonium + hydrogen peroxide - nicotine biosynthesis:
O2 + asp ⟶ 2-iminosuccinate + H+ + hydrogen peroxide - superpathway of nicotine biosynthesis:
O2 + asp ⟶ 2-iminosuccinate + H+ + hydrogen peroxide - nicotine biosynthesis:
O2 + asp ⟶ 2-iminosuccinate + H+ + hydrogen peroxide - N-methyl-Δ1-pyrrolinium cation biosynthesis:
N-methylputrescine + H2O + O2 ⟶ N-methylaminobutanal + ammonium + hydrogen peroxide - superpathway of nicotine biosynthesis:
N-methylputrescine + H2O + O2 ⟶ N-methylaminobutanal + ammonium + hydrogen peroxide - N-methyl-Δ1-pyrrolinium cation biosynthesis:
N-methylputrescine + H2O + O2 ⟶ N-methylaminobutanal + ammonium + hydrogen peroxide - nicotine biosynthesis:
O2 + asp ⟶ 2-iminosuccinate + H+ + hydrogen peroxide - superpathway of nicotine biosynthesis:
O2 + asp ⟶ 2-iminosuccinate + H+ + hydrogen peroxide - nicotine biosynthesis:
O2 + asp ⟶ 2-iminosuccinate + H+ + hydrogen peroxide - N-methyl-Δ1-pyrrolinium cation biosynthesis:
N-methylputrescine + H2O + O2 ⟶ N-methylaminobutanal + ammonium + hydrogen peroxide - cocaine biosynthesis:
NADP+ + ecgonine methyl ester ⟶ H+ + NADPH + methyl ecgonone - N-methyl-Δ1-pyrrolinium cation biosynthesis:
N-methylaminobutanal ⟶ H2O + N-methyl-Δ1-pyrrolinium cation - nicotine biosynthesis:
(S)-nicotine + O2 + a reduced [NADPH-hemoprotein reductase] ⟶ H+ + H2O + an oxidized [NADPH-hemoprotein reductase] + formate + nornicotine - superpathway of nicotine biosynthesis:
(S)-nicotine + O2 + a reduced [NADPH-hemoprotein reductase] ⟶ H+ + H2O + an oxidized [NADPH-hemoprotein reductase] + formate + nornicotine - nicotine biosynthesis:
O2 + asp ⟶ 2-iminosuccinate + H+ + hydrogen peroxide - N-methyl-Δ1-pyrrolinium cation biosynthesis:
N-methylputrescine + H2O + O2 ⟶ N-methylaminobutanal + ammonium + hydrogen peroxide - calystegine biosynthesis:
NADP+ + pseudotropine ⟶ H+ + NADPH + tropinone - superpathway of nicotine biosynthesis:
O2 + asp ⟶ 2-iminosuccinate + H+ + hydrogen peroxide - hyoscyamine and scopolamine biosynthesis:
(S)-atropine + 2-oxoglutarate + O2 ⟶ (6S)-hydroxyhyoscyamine + CO2 + succinate - superpathway of hyoscyamine and scopolamine biosynthesis:
N-methylputrescine + H2O + O2 ⟶ N-methylaminobutanal + ammonium + hydrogen peroxide - nicotine biosynthesis:
O2 + asp ⟶ 2-iminosuccinate + H+ + hydrogen peroxide - N-methyl-Δ1-pyrrolinium cation biosynthesis:
N-methylputrescine + H2O + O2 ⟶ N-methylaminobutanal + ammonium + hydrogen peroxide - superpathway of nicotine biosynthesis:
O2 + asp ⟶ 2-iminosuccinate + H+ + hydrogen peroxide - nicotine biosynthesis:
O2 + asp ⟶ 2-iminosuccinate + H+ + hydrogen peroxide - superpathway of nicotine biosynthesis:
O2 + asp ⟶ 2-iminosuccinate + H+ + hydrogen peroxide - hyoscyamine and scopolamine biosynthesis:
(S)-atropine + 2-oxoglutarate + O2 ⟶ (6S)-hydroxyhyoscyamine + CO2 + succinate - N-methyl-Δ1-pyrrolinium cation biosynthesis:
N-methylputrescine + H2O + O2 ⟶ N-methylaminobutanal + ammonium + hydrogen peroxide - calystegine biosynthesis:
NADP+ + pseudotropine ⟶ H+ + NADPH + tropinone
COVID-19 Disease Map(1)
- @COVID-19 Disease
Map["name"]:
2-Methyl-3-acetoacetyl-CoA + Coenzyme A ⟶ Acetyl-CoA + Propanoyl-CoA
PathBank(1)
- Tropane, Piperidine, and Pyridine Alkaloid Biosynthesis:
Hydrogen Ion + N-Methylputrescine + Oxygen ⟶ 1-Methylpyrrolinium + Ammonia + Hydrogen peroxide
PharmGKB(0)
3 个相关的物种来源信息
- 9606 - Homo sapiens: -
- 9606 - Homo sapiens: 10.1007/S11306-016-1051-4
- 4097 - Nicotiana tabacum: 10.1016/J.PHYTOCHEM.2006.11.003
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Jian-Ping Huang, Chengli Fang, Xiaoyan Ma, Li Wang, Jing Yang, Jianying Luo, Yijun Yan, Yu Zhang, Sheng-Xiong Huang. Tropane alkaloids biosynthesis involves an unusual type III polyketide synthase and non-enzymatic condensation.
Nature communications.
2019 09; 10(1):4036. doi:
10.1038/s41467-019-11987-z. [PMID: 31492848] - Yu Ping, Xiaodong Li, Baofu Xu, Wei Wei, Wenping Wei, Guoyin Kai, Zhihua Zhou, Youli Xiao. Building Microbial Hosts for Heterologous Production of N-Methylpyrrolinium.
ACS synthetic biology.
2019 02; 8(2):257-263. doi:
10.1021/acssynbio.8b00483. [PMID: 30691267] - Masataka Kajikawa, Nobuhiro Hirai, Takashi Hashimoto. A PIP-family protein is required for biosynthesis of tobacco alkaloids.
Plant molecular biology.
2009 Feb; 69(3):287-98. doi:
10.1007/s11103-008-9424-3. [PMID: 19002761]