N-methyl-L-glutamic Acid (BioDeep_00000003150)

 

Secondary id: BioDeep_00001868736

human metabolite BioNovoGene_Lab2019 natural product


代谢物信息卡片


(2S)-2-(Methylamino)pentanedioic acid

化学式: C6H11NO4 (161.0688)
中文名称: N-甲基谷氨酸, N-甲基-L-谷氨酸
谱图信息: 最多检出来源 Homo sapiens(plant) 12.1%

分子结构信息

SMILES: CNC(CCC(=O)O)C(=O)O
InChI: InChI=1S/C6H11NO4/c1-7-4(6(10)11)2-3-5(8)9/h4,7H,2-3H2,1H3,(H,8,9)(H,10,11)

描述信息

N-methyl-L-glutamic Acid, also known as N-Methylglutamate or (2S)-2-(methylamino)Pentanedioic acid, is classified as a glutamic acid or a Glutamic acid derivative. Glutamic acids are compounds containing glutamic acid or a derivative thereof resulting from reaction of glutamic acid at the amino group or the carboxy group, or from the replacement of any hydrogen of glycine by a heteroatom. N-methyl-L-glutamic Acid is considered to be soluble (in water) and acidic
KEIO_ID M067

同义名列表

10 个代谢物同义名

(2S)-2-(Methylamino)pentanedioic acid; (2S)-2-(Methylamino)pentanedioate; N-Methyl-DL-glutamic acid; N-methyl-L-glutamic acid; N-Methylglutamic acid; N-Methyl-L-glutamate; N-Methyl-D-glutamate; N-Methylglutamate; N-methyl-glutamic acid; N-Methyl-L-glutamic acid



数据库引用编号

27 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

10 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 4 BDNF, DAO, DDO, HSFX1
Peripheral membrane protein 2 DAO, FDXR
Nucleus 1 HSFX1
cytosol 5 DAO, DDO, GCLM, GPT, HAO2
dendrite 2 BDNF, HTR5A
Cell membrane 5 DAO, GLRA2, GRID1, HTR5A, MAG
Multi-pass membrane protein 3 GLRA2, GRID1, HTR5A
Synapse 1 GLRA2
glutamatergic synapse 1 GRID1
mitochondrial inner membrane 1 FDXR
synaptic vesicle 1 BDNF
Cytoplasm, cytosol 2 DAO, DDO
plasma membrane 5 DAO, GLRA2, GRID1, HTR5A, MAG
presynaptic active zone 1 DAO
Membrane 3 BDNF, GLRA2, MAG
axon 1 BDNF
extracellular exosome 3 DAO, GPT, GRID1
extracellular space 2 BDNF, DAO
perinuclear region of cytoplasm 1 BDNF
bicellular tight junction 1 DAO
mitochondrion 1 FDXR
intracellular membrane-bounded organelle 1 GLRA2
Single-pass type I membrane protein 1 MAG
Secreted 2 BDNF, DAO
extracellular region 2 BDNF, DAO
Single-pass membrane protein 1 MAG
mitochondrial matrix 1 FDXR
Extracellular side 1 DAO
perikaryon 1 HTR5A
postsynaptic membrane 1 GRID1
Mitochondrion inner membrane 1 FDXR
Membrane raft 1 MAG
GABA-ergic synapse 2 GLRA2, GRID1
Peroxisome 3 DAO, DDO, HAO2
Peroxisome matrix 2 DAO, DDO
peroxisomal matrix 3 DAO, DDO, HAO2
Postsynaptic cell membrane 2 GLRA2, GRID1
neuron projection 1 GLRA2
chromatin 1 HSFX1
cell projection 2 DAO, GLRA2
Secreted, extracellular space 1 DAO
transmembrane transporter complex 1 GLRA2
chloride channel complex 1 GLRA2
myelin sheath 1 MAG
endoplasmic reticulum lumen 1 BDNF
specific granule lumen 1 DAO
paranode region of axon 1 MAG
Schmidt-Lanterman incisure 1 MAG
postsynaptic density membrane 1 GRID1
postsynaptic specialization membrane 2 GLRA2, HTR5A
compact myelin 1 MAG
glycinergic synapse 1 GLRA2
myelin sheath adaxonal region 1 MAG
mesaxon 1 MAG
[Neurotrophic factor BDNF precursor form]: Secreted 1 BDNF
glutamate-cysteine ligase complex 1 GCLM
[Isoform DDO-1]: Peroxisome matrix 1 DDO
[Isoform 3]: Peroxisome matrix 1 DDO


文献列表

  • Peng Huang, Yuanjie Zou, Xi Zoë Zhong, Qi Cao, Kexin Zhao, Michael X Zhu, Ruth Murrell-Lagnado, Xian-Ping Dong. P2X4 forms functional ATP-activated cation channels on lysosomal membranes regulated by luminal pH. The Journal of biological chemistry. 2014 Jun; 289(25):17658-67. doi: 10.1074/jbc.m114.552158. [PMID: 24817123]
  • T Stuchbury, M Shipton, R Norris, J P Malthouse, K Brocklehurst, J A Herbert, H Suschitzky. A reporter group delivery system with both absolute and selective specificity for thiol groups and an improved fluorescent probe containing the 7-nitrobenzo-2-oxa-1,3-diazole moiety. The Biochemical journal. 1975 Nov; 151(2):417-32. doi: 10.1042/bj1510417. [PMID: 3168]