NORBORMIDE (BioDeep_00000002109)

   


代谢物信息卡片


NORBORMIDE

化学式: C33H25N3O3 (511.1896)
中文名称: 诺硼胺
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=CC=C(C=C1)C(=C2C3C=C(C2C4C3C(=O)NC4=O)C(C5=CC=CC=C5)(C6=CC=CC=N6)O)C7=CC=CC=N7
InChI: InChI=1S/C33H25N3O3/c37-31-28-22-19-23(33(39,21-13-5-2-6-14-21)25-16-8-10-18-35-25)29(30(28)32(38)36-31)27(22)26(20-11-3-1-4-12-20)24-15-7-9-17-34-24/h1-19,22,28-30,39H,(H,36,37,38)

描述信息

D010575 - Pesticides > D012378 - Rodenticides
D016573 - Agrochemicals

同义名列表

2 个代谢物同义名

NORBORMIDE; Norbormide



数据库引用编号

9 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 3 AXIN2, EDN1, PPP1R9A
Endoplasmic reticulum membrane 2 ATL1, HSP90B1
Mitochondrion membrane 1 TSPO
Nucleus 3 ATL1, AXIN2, HSP90B1
cytosol 3 AXIN2, HSP90B1, TSPO
dendrite 1 PPP1R9A
mitochondrial membrane 1 TSPO
centrosome 1 AXIN2
Cell projection, axon 1 ATL1
Multi-pass membrane protein 3 ATL1, CACNA1I, TSPO
Golgi apparatus membrane 1 ATL1
Synapse 1 PPP1R9A
Golgi apparatus 1 ATL1
Golgi membrane 2 ATL1, INS
smooth endoplasmic reticulum 1 HSP90B1
plasma membrane 2 AXIN2, CACNA1I
Membrane 4 ATL1, CACNA1I, HSP90B1, TSPO
axon 1 ATL1
extracellular exosome 2 HSP90B1, TSPO
endoplasmic reticulum 3 ATL1, HSP90B1, TSPO
extracellular space 2 EDN1, INS
perinuclear region of cytoplasm 1 HSP90B1
mitochondrion 1 TSPO
protein-containing complex 1 HSP90B1
intracellular membrane-bounded organelle 1 TSPO
filopodium 1 PPP1R9A
postsynaptic density 1 PPP1R9A
Secreted 2 EDN1, INS
extracellular region 3 EDN1, HSP90B1, INS
mitochondrial outer membrane 1 TSPO
basal part of cell 1 EDN1
actin cytoskeleton 1 PPP1R9A
dendritic spine 1 PPP1R9A
beta-catenin destruction complex 1 AXIN2
midbody 1 HSP90B1
Cytoplasm, cytoskeleton 1 PPP1R9A
focal adhesion 1 HSP90B1
collagen-containing extracellular matrix 1 HSP90B1
cytoskeleton 1 PPP1R9A
endosome lumen 1 INS
Melanosome 1 HSP90B1
sperm plasma membrane 1 HSP90B1
secretory granule lumen 1 INS
Golgi lumen 1 INS
endoplasmic reticulum lumen 2 HSP90B1, INS
cortical actin cytoskeleton 1 PPP1R9A
voltage-gated calcium channel complex 1 CACNA1I
transport vesicle 2 EDN1, INS
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
Sarcoplasmic reticulum lumen 1 HSP90B1
Synapse, synaptosome 1 PPP1R9A
endocytic vesicle lumen 1 HSP90B1
rough endoplasmic reticulum lumen 1 EDN1
Weibel-Palade body 1 EDN1
endoplasmic reticulum chaperone complex 1 HSP90B1
endoplasmic reticulum tubular network 1 ATL1
Golgi cis cisterna 1 ATL1
endoplasmic reticulum tubular network membrane 1 ATL1


文献列表

  • Zifei L Wang, Freda F Li, Rachelle Quach, Alessandro Ferrarese, Alessia Forgiarini, Mauro Ferrari, Claudio D'Amore, Sergio Bova, Genny Orso, Fabio Fusi, Simona Saponara, Brian Hopkins, Margaret A Brimble, David Rennison. Nitrobenzoxadiazole derivatives of the rat selective toxicant norbormide as fluorescent probes for live cell imaging. Bioorganic & medicinal chemistry. 2022 04; 59(?):116670. doi: 10.1016/j.bmc.2022.116670. [PMID: 35202967]
  • Alessia Forgiarini, Zifei Wang, Claudio D'Amore, Morgan Jay-Smith, Freda Fan Li, Brian Hopkins, Margaret Anne Brimble, Andrea Pagetta, Sara Bersani, Sara De Martin, Barbara Napoli, Sergio Bova, David Rennison, Genny Orso. Live applications of norbormide-based fluorescent probes in Drosophila melanogaster. PloS one. 2019; 14(4):e0211169. doi: 10.1371/journal.pone.0211169. [PMID: 30958824]
  • Fernanda Ricchelli, Federica Dabbeni-Sala, Valeria Petronilli, Paolo Bernardi, Brian Hopkins, Sergio Bova. Species-specific modulation of the mitochondrial permeability transition by norbormide. Biochimica et biophysica acta. 2005 Jun; 1708(2):178-86. doi: 10.1016/j.bbabio.2005.03.002. [PMID: 15953474]
  • Allan Nadian, Louise Lindblom. Studies on the development of a microencapsulated delivery system for norbormide, a species-specific acute rodenticide. International journal of pharmaceutics. 2002 Aug; 242(1-2):63-8. doi: 10.1016/s0378-5173(02)00142-4. [PMID: 12176226]