Phenylpropanolamine (BioDeep_00000002012)

 

Secondary id: BioDeep_00000397895

human metabolite Endogenous blood metabolite


代谢物信息卡片


(1S,2R)-2-amino-1-phenylpropan-1-ol

化学式: C9H13NO (151.0997088)
中文名称: 左旋去甲麻黄碱, 去甲基麻黄素
谱图信息: 最多检出来源 Mentha canadensis(plant) 3.64%

分子结构信息

SMILES: CC(C(C1=CC=CC=C1)O)N
InChI: InChI=1S/C9H13NO/c1-7(10)9(11)8-5-3-2-4-6-8/h2-7,9,11H,10H2,1H3

描述信息

Phenylpropanolamine is a sympathomimetic that acts mainly by causing release of norepinephrine but also has direct agonist activity at some adrenergic receptors. It is most commonly used as a nasal vasoconstrictor and an appetite depressant. -- Pubchem [HMDB]
Phenylpropanolamine is a sympathomimetic that acts mainly by causing release of norepinephrine but also has direct agonist activity at some adrenergic receptors. It is most commonly used as a nasal vasoconstrictor and an appetite depressant. -- Pubchem.
R - Respiratory system > R01 - Nasal preparations > R01B - Nasal decongestants for systemic use > R01BA - Sympathomimetics
D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents > D013566 - Sympathomimetics
D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents > D000322 - Adrenergic Agonists
D019141 - Respiratory System Agents > D014663 - Nasal Decongestants
D002317 - Cardiovascular Agents > D014662 - Vasoconstrictor Agents
D019440 - Anti-Obesity Agents > D001067 - Appetite Depressants
CONFIDENCE standard compound; INTERNAL_ID 1547

同义名列表

22 个代谢物同义名

(1S,2R)-2-amino-1-phenylpropan-1-ol; Hydrochloride, phenylpropanolamine; Phenylpropanolamine hydrochloride; 2-Amino-1-phenyl-1-propanol; (1S,2R)-(+)-Norephedrine; DL-Phenylpropanolamine; L-Phenyl propanolamine; phenylpropanolamine; DL-Norephedrine; D-Norephedrine; L-NOREPHEDRINE; Prestwick_388; Norephedrine; Triaminic DM; Hydriatine; Propadrine; Prolamine; Propagest; Dexatrim; Mucorama; Obestat; Nobese



数据库引用编号

21 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

14 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Jian Guo, Zhiping He, Chao Ma, Wanting Li, Jiaoyu Wang, Fucheng Lin, Xingquan Liu, Ling Li. Evaluation of cold plasma for decontamination of molds and mycotoxins in rice grain. Food chemistry. 2023 Feb; 402(?):134159. doi: 10.1016/j.foodchem.2022.134159. [PMID: 36137380]
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  • Shuai Song, Qingfa Tang, Huiling Huo, Hancheng Li, Xuefeng Xing, Jiabo Luo. Simultaneous quantification and pharmacokinetics of alkaloids in Herba Ephedrae-Radix Aconiti Lateralis extracts. Journal of analytical toxicology. 2015 Jan; 39(1):58-68. doi: 10.1093/jat/bku113. [PMID: 25324527]
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  • Ravinder Earla, Santosh Kumar, Lei Wang, Steven Bosinger, Junhao Li, Ankit Shah, Mohitkumar Gangwani, Anantha Nookala, Xun Liu, Lu Cao, Austin Jackson, Peter S Silverstein, Howard S Fox, Weihua Li, Anil Kumar. Enhanced methamphetamine metabolism in rhesus macaque as compared with human: an analysis using a novel method of liquid chromatography with tandem mass spectrometry, kinetic study, and substrate docking. Drug metabolism and disposition: the biological fate of chemicals. 2014 Dec; 42(12):2097-108. doi: 10.1124/dmd.114.059378. [PMID: 25301936]
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