(8S)-2-Bromo alpha-ergocryptine (BioDeep_00001884194)
代谢物信息卡片
(8S)-2-Bromo alpha-ergocryptine
化学式: C32H40BrN5O5 (653.221265)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC(C)CC1C(=O)N2CCCC2C3(N1C(=O)C(O3)(C(C)C)NC(=O)C4CN(C5CC6=C(NC7=CC=CC(=C67)C5=C4)Br)C)O
InChI: InChI=1S/C32H40BrN5O5/c1-16(2)12-24-29(40)37-11-7-10-25(37)32(42)38(24)30(41)31(43-32,17(3)4)35-28(39)18-13-20-19-8-6-9-22-26(19)21(27(33)34-22)14-23(20)36(5)15-18/h6,8-9,13,16-18,23-25,34,42H,7,10-12,14-15H2,1-5H3,(H,35,39)
描述信息
D002491 - Central Nervous System Agents > D018726 - Anti-Dyskinesia Agents > D000978 - Antiparkinson Agents
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006727 - Hormone Antagonists
D018377 - Neurotransmitter Agents > D015259 - Dopamine Agents > D018491 - Dopamine Agonists
同义名列表
1 个代谢物同义名
相关代谢途径
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代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
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PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Milica Vranic, Fozia Ahmed, Robin Kristófi, Susanne Hetty, Dariush Mokhtari, Maria K Svensson, Jan W Eriksson, Maria J Pereira. Subcutaneous adipose tissue dopamine D2 receptor is increased in prediabetes and T2D.
Endocrine.
2023 Sep; ?(?):. doi:
10.1007/s12020-023-03525-1. [PMID: 37752366] - Shang Guo, Nannan Qin, Xiuying Wang, Zanwen Zuo, Qizhang Li, Yuliang Wang. Freeze-dried powder of daylily bud improves bromocriptine-induced lactation disorder in rats via JAK2/STAT5 pathway.
Journal of ethnopharmacology.
2023 Apr; 313(?):116536. doi:
10.1016/j.jep.2023.116536. [PMID: 37120059] - Víctor H Castillo-Campohermoso, Luz M Molina-Martínez, Eliana Barrios de Tomasi, Jorge Juárez. Co-administration of bromocriptine and corticosterone produces short- and long-lasting reduction in intake of high-fat food in male rats.
Behavioural pharmacology.
2023 02; 34(1):1-11. doi:
10.1097/fbp.0000000000000706. [PMID: 36730784] - Sandip Debnath, Devesh Sharma, Somdatta Yashwant Chaudhari, Ritika Sharma, Amir Afzal Shaikh, Rahul Subhash Buchade, Kavindra Kumar Kesari, Abdel-Fattah M Abdel-Fattah, Mohammad Algahtani, Mayyadah Mheidat, Rawidh Alsaidalani, Tapas Paul, Amany A Sayed, Mohamed M Abdel-Daim. Wheat ergot fungus-derived and modified drug for inhibition of intracranial aneurysm rupture due to dysfunction of TLR-4 receptor in Alzheimer's disease.
PloS one.
2023; 18(1):e0279616. doi:
10.1371/journal.pone.0279616. [PMID: 36656815] - Tomohito Mizuno, Riku Takahashi, Takahiro Kamiyama, Atsushi Suzuki, Masashi Suzuki. Neuroleptic Malignant Syndrome with Adrenal Insufficiency After BNT162b2 COVID-19 Vaccination in a Man Taking Valproate: A Case Report.
The American journal of case reports.
2022 May; 23(?):e936217. doi:
10.12659/ajcr.936217. [PMID: 35514081] - Muhammad Usama Ashhar, Preeti Vyas, Divya Vohora, Pravat Kumar Sahoo, Kuldeep Nigam, Shweta Dang, Javed Ali, Sanjula Baboota. Amelioration of oxidative stress utilizing nanoemulsion loaded with bromocriptine and glutathione for the management of Parkinson's disease.
International journal of pharmaceutics.
2022 Apr; 618(?):121683. doi:
10.1016/j.ijpharm.2022.121683. [PMID: 35314276] - Shinnosuke Masuda, Oh Kwan Ee, Taku James Sairenji, Seika Sato, Hiroyuki Yajima, Izuki Amano, Noriyuki Koibuchi, Noriaki Shimokawa. Maternal prolactin levels during late pregnancy and nurturing behavior of offspring in mice.
Developmental psychobiology.
2022 03; 64(3):e22264. doi:
10.1002/dev.22264. [PMID: 35312052] - Zain Ul-Abideen, Hafiz Ishfaq Ahmad, Muhammad Nadeem, Aleem Ahmad Khan, Muhammad Imran, Tanveer Majeed, Shouqun Jiang, Abdelmotaleb Elokil. The therapeutic effect of bromocriptine as mesylate and estradiol valerate on serum and blood biochemistry of common quails.
Poultry science.
2022 Feb; 101(2):101552. doi:
10.1016/j.psj.2021.101552. [PMID: 34942520] - Rosa Pirchio, Chiara Graziadio, Annamaria Colao, Rosario Pivonello, Renata S Auriemma. Metabolic effects of prolactin.
Frontiers in endocrinology.
2022; 13(?):1015520. doi:
10.3389/fendo.2022.1015520. [PMID: 36237192] - Bianca N Mason, Rohini Kallianpur, Theodore J Price, Armen N Akopian, Gregory O Dussor. Prolactin signaling modulates stress-induced behavioral responses in a preclinical mouse model of migraine.
Headache.
2022 Jan; 62(1):11-25. doi:
10.1111/head.14248. [PMID: 34967003] - Hua Feng, Qiuxi Zhong, Huifang Zhou, Xiaoyue Jiang, Yinyin Ding. The effects of combined bromocriptine and Bu-shen-zhu-yun decoction on serum hormones, anxiety, and pregnancy in hyperprolactinemic infertility patients.
Annals of palliative medicine.
2021 Dec; 10(12):12230-12243. doi:
10.21037/apm-21-3111. [PMID: 35016475] - Merve Yuce, Erdem Cicek, Tugce Inan, Aslihan Basak Dag, Ozge Kurkcuoglu, Fethiye Aylin Sungur. Repurposing of FDA-approved drugs against active site and potential allosteric drug-binding sites of COVID-19 main protease.
Proteins.
2021 11; 89(11):1425-1441. doi:
10.1002/prot.26164. [PMID: 34169568] - Mohammed Ahmed Fouad Shalaby, Hekma A Abd El Latif, Mohamed El Yamani, May Ahmed Galal, Sherifa Kamal, Ikhlas Sindi, Raneem Masaood. Therapeutic activity of sarpogrelate and dopamine D2 receptor agonists on cardiovascular and renal systems in rats with alloxan-induced diabetes.
BMC pharmacology & toxicology.
2021 10; 22(1):64. doi:
10.1186/s40360-021-00526-6. [PMID: 34702339] - G Tavares, D Marques, C Barra, D Rosendo-Silva, A Costa, T Rodrigues, P Gasparini, B F Melo, J F Sacramento, R Seiça, S V Conde, P Matafome. Dopamine D2 receptor agonist, bromocriptine, remodels adipose tissue dopaminergic signalling and upregulates catabolic pathways, improving metabolic profile in type 2 diabetes.
Molecular metabolism.
2021 09; 51(?):101241. doi:
10.1016/j.molmet.2021.101241. [PMID: 33933677] - Michael Ezrokhi, Yahong Zhang, Shuqin Luo, Anthony H Cincotta. Time-of-Day-Dependent Effects of Bromocriptine to Ameliorate Vascular Pathology and Metabolic Syndrome in SHR Rats Held on High Fat Diet.
International journal of molecular sciences.
2021 Jun; 22(11):. doi:
10.3390/ijms22116142. [PMID: 34200262] - Maria Camila Moreno-Escobar, Saurabh Kataria, Erum Khan, Roshan Subedi, Medha Tandon, Krithika Peshwe, Joshua Kramer, Faraze Niaze, Shitiz Sriwastava. Acute transverse myelitis with Dysautonomia following SARS-CoV-2 infection: A case report and review of literature.
Journal of neuroimmunology.
2021 04; 353(?):577523. doi:
10.1016/j.jneuroim.2021.577523. [PMID: 33640717] - Motoyuki Igata, Yoshitaka Yagi, Satoko Hanatani, Masaji Sakaguchi, Norio Ishii, Kayo Yoshinaga, Junji Kawashima, Hiroyuki Motoshima, Eiichi Araki. Rapid and dramatic glucose-lowering effect of bromocriptine in an inadequately controlled type 2 diabetes patient with prolactinoma.
Journal of diabetes investigation.
2021 Apr; 12(4):668-671. doi:
10.1111/jdi.13369. [PMID: 32706496] - Iala Milene Bertasso, Carla Bruna Pietrobon, Beatriz Souza da Silva, Rosiane Aparecida Miranda, Maria Lucia Bonfleur, Sandra Lucinei Balbo, Alex Christian Manhães, Elaine Oliveira, Egberto Gaspar de Moura, Patricia Cristina Lisboa. Hepatic lipid metabolism in adult rats using early weaning models: sex-related differences.
Journal of developmental origins of health and disease.
2020 10; 11(5):499-508. doi:
10.1017/s2040174420000495. [PMID: 32519629] - Jie Yin, Kuang-Yui M Chen, Mary J Clark, Mahdi Hijazi, Punita Kumari, Xiao-Chen Bai, Roger K Sunahara, Patrick Barth, Daniel M Rosenbaum. Structure of a D2 dopamine receptor-G-protein complex in a lipid membrane.
Nature.
2020 08; 584(7819):125-129. doi:
10.1038/s41586-020-2379-5. [PMID: 32528175] - Raahil Kajani, Austin Apramian, Arturo Vega, Nitin Ubhayakar, Prissilla Xu, Antonio Liu. Neuroleptic malignant syndrome in a COVID-19 patient.
Brain, behavior, and immunity.
2020 08; 88(?):28-29. doi:
10.1016/j.bbi.2020.05.042. [PMID: 32425332] - Carla Bruna Pietrobon, Iala Milene Bertasso, Beatrix S Silva, Nayara Peixoto-Silva, Elaine Oliveira, Egberto Gaspar Moura, Patricia Cristina Lisboa. Body Adiposity and Endocrine Profile of Female Wistar Rats of Distinct Ages that were Early Weaned.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.
2020 Jan; 52(1):58-66. doi:
10.1055/a-0966-8784. [PMID: 31537024] - Tamami Oshige, Yui Nakamura, Yuko Sasaki, Seiko Kawano, Tsuyoshi Ohki, Munehisa Tsuruta, Ichiro Tokubuchi, Hitomi Nakayama, Kentaro Yamada, Kenji Ashida, Yuji Tajiri, Masatoshi Nomura. Bromocriptine as a Potential Glucose-lowering Agent for the Treatment of Prolactinoma with Type 2 Diabetes.
Internal medicine (Tokyo, Japan).
2019 Nov; 58(21):3125-3128. doi:
10.2169/internalmedicine.2755-19. [PMID: 31243214] - Robert Krysiak, Bogusław Okopień. Sexual Functioning in Hyperprolactinemic Patients Treated With Cabergoline or Bromocriptine.
American journal of therapeutics.
2019 Jul; 26(4):e433-e440. doi:
10.1097/mjt.0000000000000777. [PMID: 29746287] - Ana Velosa, António Neves, J Bernardo Barahona-Corrêa, Albino J Oliveira-Maia. Neuroleptic malignant syndrome: a concealed diagnosis with multitreatment approach.
BMJ case reports.
2019 Jun; 12(6):. doi:
10.1136/bcr-2018-225840. [PMID: 31213433] - Kosuke Mukai, Michio Otsuki, Daisuke Tamada, Tetsuhiro Kitamura, Reiko Hayashi, Aya Saiki, Yuko Goto, Hideyuki Arita, Satoru Oshino, Eiichi Morii, Youichi Saitoh, Iichiro Shimomura. Clinical Characteristics of Acromegalic Patients With Paradoxical GH Response to Oral Glucose Load.
The Journal of clinical endocrinology and metabolism.
2019 05; 104(5):1637-1644. doi:
10.1210/jc.2018-00975. [PMID: 30476255] - Robert Krysiak, Witold Szkróbka, Bogusław Okopień. Different effects of fenofibrate on cardiometabolic risk factors in young women with and without hyperprolactinemia.
Pharmacological reports : PR.
2019 Feb; 71(1):61-66. doi:
10.1016/j.pharep.2018.09.004. [PMID: 30469130] - Isadora C Furigo, Miriam F Suzuki, João E Oliveira, Angela M Ramos-Lobo, Pryscila D S Teixeira, João A Pedroso, Amanda de Alencar, Thais T Zampieri, Daniella C Buonfiglio, Paula G F Quaresma, Patricia O Prada, Paolo Bartolini, Carlos R J Soares, Jose Donato. Suppression of Prolactin Secretion Partially Explains the Antidiabetic Effect of Bromocriptine in ob/ob Mice.
Endocrinology.
2019 01; 160(1):193-204. doi:
10.1210/en.2018-00629. [PMID: 30462197] - Mohamed Soliman, Fathia M Khattab, Howyda Mohamed Ebrahim, Mohamad Nasr. Serum prolactin level in chronic urticaria: Is bromocriptine inducing remission in chronic urticaria?.
The Journal of dermatological treatment.
2018 Dec; 29(8):826-830. doi:
10.1080/09546634.2018.1468062. [PMID: 29694255] - Jun Gao, Yang Liu, Gaijing Han, Kan Deng, Xiaohai Liu, Xinjie Bao, Ming Feng, Yong Yao, Wei Lian, Bing Xing, Xiang Lv, Renzhi Wang. Metformin inhibits growth and prolactin secretion of pituitary prolactinoma cells and xenografts.
Journal of cellular and molecular medicine.
2018 12; 22(12):6368-6379. doi:
10.1111/jcmm.13963. [PMID: 30334324] - Suresh Palle, Prasad Neerati. Quercetin nanoparticles alter pharmacokinetics of bromocriptine, reflecting its enhanced inhibitory action on liver and intestinal CYP 3A enzymes in rats.
Xenobiotica; the fate of foreign compounds in biological systems.
2018 Oct; 48(10):1028-1036. doi:
10.1080/00498254.2017.1390277. [PMID: 28990837] - Ana C L Camargo, Flávia B Constantino, Sérgio A A Santos, Ketlin T Colombelli, Maeli Dal-Pai-Silva, Sérgio L Felisbino, Luis A Justulin. Influence of postnatal prolactin modulation on the development and maturation of ventral prostate in young rats.
Reproduction, fertility, and development.
2018 Jun; 30(7):969-979. doi:
10.1071/rd17343. [PMID: 29207253] - Hai Yan Huang, Shao Jian Lin, Wei Guo Zhao, Zhe Bao Wu. Cabergoline versus bromocriptine for the treatment of giant prolactinomas: A quantitative and systematic review.
Metabolic brain disease.
2018 06; 33(3):969-976. doi:
10.1007/s11011-018-0217-3. [PMID: 29546691] - Chengxian Yang, Huanwen Wu, Jing Wang, Mingming Hu, Xiaoping Xing, Xinjie Bao, Renzhi Wang. Successful management of octreotide-insensitive thyrotropin-secreting pituitary adenoma with bromocriptine and surgery: A case report and literature review.
Medicine.
2017 Sep; 96(36):e8017. doi:
10.1097/md.0000000000008017. [PMID: 28885368] - Margarida Teixeira, Pedro Souteiro, Davide Carvalho. Prolactinoma management: predictors of remission and recurrence after dopamine agonists withdrawal.
Pituitary.
2017 Aug; 20(4):464-470. doi:
10.1007/s11102-017-0806-x. [PMID: 28523537] - Robert Krysiak, Witold Szkróbka, Bogusław Okopień. Alternative Treatment Strategies in Women Poorly Tolerating Moderate Doses of Bromocriptine.
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association.
2017 Jun; 125(6):360-364. doi:
10.1055/s-0042-123041. [PMID: 28073129] - Bindu Chamarthi, Anthony H Cincotta. Effect of bromocriptine-QR therapy on glycemic control in subjects with type 2 diabetes mellitus whose dysglycemia is inadequately controlled on insulin.
Postgraduate medicine.
2017 May; 129(4):446-455. doi:
10.1080/00325481.2017.1315290. [PMID: 28374645] - K V Derkach, A O Ivantsov, I B Sukhov, A O Shpakov. THE RESTORATION OF HYPOTHALAMIC SIGNALING SYSTEMS AS ONE OF THE CAUSES TO IMPROVE THE METABOLIC PARAMETERS IN BROMOCRYPTINE-TREATED RATS WITH NEONATAL MODEL OF DIABETES MELLITUS.
Tsitologiia.
2017 ; 59(2):140-7. doi:
. [PMID: 30199162] - Oliva Mejía-Rodríguez, Humberto Ruiz-Vega, Cleto Álvarez-Aguilar, Marcela Ávila-Díaz, Silvia Palomo-Piñón, José Ramón Paniagua-Sierra. Blood pressure rhythmicity in patients with end stage chronic kidney disease: bromocriptine effect.
Revista medica del Instituto Mexicano del Seguro Social.
2017; 55(Suppl 2):S182-7. doi:
NULL. [PMID: 29697240] - Janaine C Carvalho, Patricia C Lisboa, Elaine de Oliveira, Nayara Peixoto-Silva, Jessica L Nobre, Mabel C Fraga, Alex C Manhães, Egberto G Moura. Effects of postnatal bromocriptine injection on thyroid function and prolactinemia of rats at adulthood.
Neuropeptides.
2016 Oct; 59(?):71-81. doi:
10.1016/j.npep.2016.05.003. [PMID: 27261099] - Xiaojing Chen, Xiaoqing Yang, Rongrong Wu, Weiwei Chen, Huihui Xie, Xia Qian, Yuquan Zhang. Therapeutic effects of Wharton jelly-derived mesenchymal stem cells on rat abortion models.
The journal of obstetrics and gynaecology research.
2016 Aug; 42(8):972-82. doi:
10.1111/jog.12984. [PMID: 27147487] - Hengxi Chen, Jing Fu, Wei Huang. Dopamine agonists for preventing future miscarriage in women with idiopathic hyperprolactinemia and recurrent miscarriage history.
The Cochrane database of systematic reviews.
2016 Jul; 7(?):CD008883. doi:
10.1002/14651858.cd008883.pub2. [PMID: 27455388] - Janaine C Carvalho, Patricia C Lisboa, Elaine de Oliveira, Nayara Peixoto-Silva, Cintia R Pinheiro, Mabel C Fraga, Sylvio Claudio-Neto, Celso R Franci, Alex C Manhães, Egberto G Moura. Effects of early and late neonatal bromocriptine treatment on hypothalamic neuropeptides, dopaminergic reward system and behavior of adult rats.
Neuroscience.
2016 06; 325(?):175-87. doi:
10.1016/j.neuroscience.2016.03.046. [PMID: 27038750] - Yu Pan, Jing Lv, Rui Guo, Mengyi Pan, Yifan Zhang. Pituitary Prolactinoma Imaged by 99mTc-Sestamibi SPECT/CT in a Multiple Endocrine Neoplasia Type 1 Patient.
Clinical nuclear medicine.
2016 Jun; 41(6):497-9. doi:
10.1097/rlu.0000000000001144. [PMID: 26828146] - Robert Krysiak, Joanna Okrzesik, Witold Szkrobka, Bogusław Okopień. The effect of fenofibrate on cardiometabolic risk factors in bromocriptine-treated women with mixed dyslipidemia: A pilot study.
Pharmacological reports : PR.
2016 Feb; 68(1):185-9. doi:
10.1016/j.pharep.2015.08.008. [PMID: 26721371] - Yasir Hasan Siddique, Wasi Khan, Ambreen Fatima, Smita Jyoti, Saba Khanam, Falaq Naz, Rahul, Fahad Ali, Braj Raj Singh, Alim Hussain Naqvi. Effect of bromocriptine alginate nanocomposite (BANC) on a transgenic Drosophila model of Parkinson's disease.
Disease models & mechanisms.
2016 Jan; 9(1):63-8. doi:
10.1242/dmm.022145. [PMID: 26542705] - Robert Krysiak, Wojciech Gilowski, Witold Szkrobka, Bogusław Okopien. The Effect of Atorvastatin on Cardiometabolic Risk Factors in Bromocriptine-Treated Premenopausal Women with Isolated Hypercholesterolemia.
Cardiovascular therapeutics.
2015 Oct; 33(5):282-7. doi:
10.1111/1755-5922.12143. [PMID: 26146893] - W Liang, L Gao, N Li, B Wang, L Wang, Y Wang, H Yang, L You, J Hou, S Chen, H Zhu, Y Jiang, H Pan. Efficacy and Safety of Bromocriptine-QR in Type 2 Diabetes: A Systematic Review and Meta-Analysis.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.
2015 Oct; 47(11):805-12. doi:
10.1055/s-0035-1559684. [PMID: 26332757] - R Krysiak, J Okrzesik, B Okopien. Different Effects of Metformin on the Hypothalamic-Pituitary-Thyroid Axis in Bromocriptine- and Cabergoline-treated Patients with Hashimoto's Thyroiditis and Glucose Metabolism Abnormalities.
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association.
2015 Oct; 123(9):561-6. doi:
10.1055/s-0035-1564073. [PMID: 26372847] - Yuanyi Wei, Xian Wang, Zhiling Yu, Wenqi Zhou, Lili Wang, Fei Qin, Chunxia Wang, Lianbing Hou. Efficacy and Mechanism of Action of Yiru Tiaojing Granule Against Hyperprolactinemia In Vitro and In Vivo.
Planta medica.
2015 Sep; 81(14):1255-62. doi:
10.1055/s-0035-1546208. [PMID: 26252831] - J C Carvalho, E de Oliveira, N Peixoto-Silva, M C Fraga, J L Nobre, P C Lisboa, E G Moura. Maternal prolactin inhibition causes changes in leptin at 22- and 30-day-old pups.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.
2015 Jun; 47(7):528-36. doi:
10.1055/s-0034-1394379. [PMID: 25372778] - Robert Krysiak, Joanna Okrzesik, Boguslaw Okopien. The effect of short-term metformin treatment on plasma prolactin levels in bromocriptine-treated patients with hyperprolactinaemia and impaired glucose tolerance: a pilot study.
Endocrine.
2015 May; 49(1):242-9. doi:
10.1007/s12020-014-0428-2. [PMID: 25239203] - A Arduc, F Gokay, S Isik, U Ozuguz, G Akbaba, Y Tutuncu, D Berker, F K Kucukler, Y Aydin, S Guler. Retrospective comparison of cabergoline and bromocriptine effects in hyperprolactinemia: a single center experience.
Journal of endocrinological investigation.
2015 Apr; 38(4):447-53. doi:
10.1007/s40618-014-0212-4. [PMID: 25421155] - Philip Finny, Charles Stephen, Rajesh Jacob, Prathap Tharyan, Mandalam S Seshadri. Jasmine flower extract lowers prolactin.
Tropical doctor.
2015 Apr; 45(2):118-22. doi:
10.1177/0049475514560212. [PMID: 25505191] - Robert Krysiak, Bogusław Okopien. Different effects of cabergoline and bromocriptine on metabolic and cardiovascular risk factors in patients with elevated prolactin levels.
Basic & clinical pharmacology & toxicology.
2015 Mar; 116(3):251-6. doi:
10.1111/bcpt.12307. [PMID: 25123447] - Qiu Qian, Liang Liuqin, Li Hao, Yuan Shiwen, Zhan Zhongping, Chen Dongying, Lian Fan, Xu Hanshi, Yang Xiuyan, Ye Yujin. The effects of bromocriptine on preventing postpartum flare in systemic lupus erythematosus patients from South China.
Journal of immunology research.
2015; 2015(?):316965. doi:
10.1155/2015/316965. [PMID: 25973434] - R S E Brown, A E Herbison, D R Grattan. Prolactin regulation of kisspeptin neurones in the mouse brain and its role in the lactation-induced suppression of kisspeptin expression.
Journal of neuroendocrinology.
2014 Dec; 26(12):898-908. doi:
10.1111/jne.12223. [PMID: 25207795] - Digvijay G Rana, Amrutlal K Patel, Chaitanya G Joshi, Mayurdhvaj K Jhala, Ramesh K Goyal. Alteration in the expression of exon IIC transcripts of brain-derived neurotrophic factor gene by simvastatin [correction of simvastain] in chronic mild stress in mice: a possible link with dopaminergic pathway.
Canadian journal of physiology and pharmacology.
2014 Dec; 92(12):985-92. doi:
10.1139/cjpp-2014-0125. [PMID: 25389630] - Zenei Arihara, Kanako Sakurai, Rika Yamashita, Satsuki Niitsuma, Takayuki Ueno, Nao Yamamura, Shozo Yamada, Naoko Inoshita, Kazuhiro Takahashi. Bromocriptine, a dopamine agonist, increases growth hormone secretion in a patient with acromegaly.
The Tohoku journal of experimental medicine.
2014 10; 234(2):129-35. doi:
10.1620/tjem.234.129. [PMID: 25253414] - Justyna Holka-Pokorska, Agnieszka Piróg-Balcerzak, Artur Stefanowicz. ["Mid-stimulation psychosis" in the course of in vitro fertilization procedure with the use of clomiphene citrate and bromocriptine - case study].
Psychiatria polska.
2014 Sep; 48(5):901-16. doi:
10.12740/pp/24434. [PMID: 25639012] - Sarwar Malik, Syed Zubair Hussain, Rabia Basit, Najia Idress, Aysha Habib, Muhammad Zamant, Najmul Islam. Demographic characteristics, presentations and treatment outcome of patients with prolactinoma.
Journal of Ayub Medical College, Abbottabad : JAMC.
2014 Jul; 26(3):269-74. doi:
NULL. [PMID: 25671924] - Calen P Ryan, Alistair Dawson, Peter J Sharp, Simone L Meddle, Tony D Williams. Circulating breeding and pre-breeding prolactin and LH are not associated with clutch size in the zebra finch (Taeniopygia guttata).
General and comparative endocrinology.
2014 Jun; 202(?):26-34. doi:
10.1016/j.ygcen.2014.04.006. [PMID: 24768674] - Shadab Md, Shadabul Haque, Mohammad Fazil, Manish Kumar, Sanjula Baboota, Jasjeet K Sahni, Javed Ali. Optimised nanoformulation of bromocriptine for direct nose-to-brain delivery: biodistribution, pharmacokinetic and dopamine estimation by ultra-HPLC/mass spectrometry method.
Expert opinion on drug delivery.
2014 Jun; 11(6):827-42. doi:
10.1517/17425247.2014.894504. [PMID: 24655115] - Yuko Goto, Manabu Kinoshita, Satoru Oshino, Hideyuki Arita, Tetsuhiro Kitamura, Michio Otsuki, Iichiro Shimomura, Toshiki Yoshimine, Youichi Saitoh. Gsp mutation in acromegaly and its influence on TRH-induced paradoxical GH response.
Clinical endocrinology.
2014 May; 80(5):714-9. doi:
10.1111/cen.12336. [PMID: 24111551] - Roberta Araujo-Lopes, Jessica R Crampton, Nayara S S Aquino, Roberta M Miranda, Ilona C Kokay, Adelina M Reis, Celso R Franci, David R Grattan, Raphael E Szawka. Prolactin regulates kisspeptin neurons in the arcuate nucleus to suppress LH secretion in female rats.
Endocrinology.
2014 Mar; 155(3):1010-20. doi:
10.1210/en.2013-1889. [PMID: 24456164] - Yohei Tsuchida, Yoshikatsu Kaneko, Tadashi Otsuka, Kei Goto, Akihiko Saito, Keiko Yamamoto, Tadashi Yamamoto, Ichiei Narita. Upregulation of prolactin receptor in proximal tubular cells was induced in cardiac dysfunction model mice.
Clinical and experimental nephrology.
2014 Feb; 18(1):65-74. doi:
10.1007/s10157-013-0820-x. [PMID: 23712540] - Nayara Peixoto-Silva, Ellen P S Conceição, Janaine C Carvalho, Natália S Lima, José Firmino Nogueira-Neto, Elaine de Oliveira, Egberto G Moura, Patricia C Lisboa. Does bromocriptine play a role in decreasing oxidative stress for early weaned programmed obesity?.
Life sciences.
2014 Jan; 95(1):14-21. doi:
10.1016/j.lfs.2013.12.013. [PMID: 24361363] - Arijit Ghosh, Nilanjan Sengupta, Pranab Sahana, Debasis Giri, Parama Sengupta, Nina Das. Efficacy and safety of add on therapy of bromocriptine with metformin in Indian patients with type 2 diabetes mellitus: a randomized open labeled phase IV clinical trial.
Indian journal of pharmacology.
2014 Jan; 46(1):24-8. doi:
10.4103/0253-7613.125160. [PMID: 24550580] - Ratikorn Saejong, Chongdee Dangrat, Kitirat Techatrisak, Surasak Angsuwatthana, Manee Rattanachaiyanont, Prasong Tanmahasamut. Hyperprolactinemia: a 12-year retrospective study at gynecologic endocrinology unit, Siriraj Hospital.
Journal of the Medical Association of Thailand = Chotmaihet thangphaet.
2013 Oct; 96(10):1247-56. doi:
NULL. [PMID: 24350404] - Yun-Shan Deng, Jin-Fang Zhou, Xia-Yun Li, Xun-Ning Wu, Qi-Sheng Gan, Yao-Fan Wu, Feng-Ying Su. [Qilin pills combined with bromocriptine for idiopathic hyperprolactinemic oligoasthenozoospermia].
Zhonghua nan ke xue = National journal of andrology.
2013 Oct; 19(10):940-4. doi:
NULL. [PMID: 24218952] - G Boaventura, G Casimiro-Lopes, C C Pazos-Moura, E Oliveira, P C Lisboa, E G Moura. Effects of running wheel training on adult obese rats programmed by maternal prolactin inhibition.
The Journal of endocrinology.
2013 Oct; 219(1):29-37. doi:
10.1530/joe-13-0102. [PMID: 23863192] - Anne-Mathilde Thierry, Sophie Brajon, Sylvie Massemin, Yves Handrich, Olivier Chastel, Thierry Raclot. Decreased prolactin levels reduce parental commitment, egg temperatures, and breeding success of incubating male Adélie penguins.
Hormones and behavior.
2013 Sep; 64(4):737-47. doi:
10.1016/j.yhbeh.2013.06.003. [PMID: 23770271] - A Haghikia, E Podewski, E Libhaber, S Labidi, D Fischer, P Roentgen, D Tsikas, J Jordan, R Lichtinghagen, C S von Kaisenberg, I Struman, N Bovy, K Sliwa, J Bauersachs, Denise Hilfiker-Kleiner. Phenotyping and outcome on contemporary management in a German cohort of patients with peripartum cardiomyopathy.
Basic research in cardiology.
2013 Jul; 108(4):366. doi:
10.1007/s00395-013-0366-9. [PMID: 23812247] - Yoshikazu Taketa, Kaoru Inoue, Miwa Takahashi, Jyoji Yamate, Midori Yoshida. Differential morphological effects in rat corpora lutea among ethylene glycol monomethyl ether, atrazine, and bromocriptine.
Toxicologic pathology.
2013 Jul; 41(5):736-43. doi:
10.1177/0192623312464305. [PMID: 23076038] - Rajib Mukherjee, Jong Won Yun. Bromocriptine inhibits adipogenesis and lipogenesis by agonistic action on α2-adrenergic receptor in 3T3-L1 adipocyte cells.
Molecular biology reports.
2013 May; 40(5):3783-92. doi:
10.1007/s11033-012-2455-5. [PMID: 23271132] - Ana Lúcia Beltrame, Paulo Serafini, Eduardo L A Motta, José Maria Soares Júnior, Edmund C Baracat. The effects of bromocriptine on VEGF, kidney function and ovarian hyperstimulation syndrome in in vitro fertilization patients: a pilot study.
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology.
2013 Mar; 29(3):201-4. doi:
10.3109/09513590.2012.736554. [PMID: 23167783] - Oliva Mejía-Rodríguez, Jorge E Herrera-Abarca, Guillermo Ceballos-Reyes, Marcela Avila-Diaz, Carmen Prado-Uribe, Francisco Belio-Caro, Antonio Salinas-González, Helios Vega-Gomez, Cleto Alvarez-Aguilar, Bengt Lindholm, Elvia García-López, Ramón Paniagua. Cardiovascular and renal effects of bromocriptine in diabetic patients with stage 4 chronic kidney disease.
BioMed research international.
2013; 2013(?):104059. doi:
10.1155/2013/104059. [PMID: 23984312] - Di Wang, Hei Kiu Wong, Li Zhang, Grainne M McAlonan, Xiao-Min Wang, Stephen Cho Wing Sze, Yi-Bin Feng, Zhang-Jin Zhang. Not only dopamine D2 receptors involved in Peony-Glycyrrhiza Decoction, an herbal preparation against antipsychotic-associated hyperprolactinemia.
Progress in neuro-psychopharmacology & biological psychiatry.
2012 Dec; 39(2):332-8. doi:
10.1016/j.pnpbp.2012.07.005. [PMID: 22796279] - Jun Bian, Cun-Dong Liu, Xiang-Zhou Sun, Chun-Hua Deng, Yan-Ping Huang, Yun-Lin Ye. [Efficacy of compound xuanju capsule combined with bromocriptine on hyperprolactinemia-induced erectile dysfunction].
Zhonghua nan ke xue = National journal of andrology.
2012 Nov; 18(11):1023-7. doi:
NULL. [PMID: 23214255] - Vandana S Nade, Laxman A Kawale, Umesh B Todmal, Anjali B Tajanpure. Effect of bromocriptine on cardiovascular complications associated with metabolic syndrome in fructose fed rats.
Indian journal of pharmacology.
2012 Nov; 44(6):688-93. doi:
10.4103/0253-7613.103248. [PMID: 23248395] - In Ki Kim, So Jung Park, Jhang Ho Park, Seung-Ho Lee, Sung Eun Hong, John C Reed. Cyclosporine A and bromocriptine attenuate cell death mediated by intracellular calcium mobilization.
BMB reports.
2012 Aug; 45(8):482-7. doi:
10.5483/bmbrep.2012.45.8.024. [PMID: 22917034] - Katrin Walenta, Viktoria Schwarz, Stephan H Schirmer, Ingrid Kindermann, Erik B Friedrich, Erich Franz Solomayer, Karen Sliwa, Saida Labidi, Denise Hilfiker-Kleiner, Michael Böhm. Circulating microparticles as indicators of peripartum cardiomyopathy.
European heart journal.
2012 Jun; 33(12):1469-79. doi:
10.1093/eurheartj/ehr485. [PMID: 22307461] - Ian S Patten, Sarosh Rana, Sajid Shahul, Glenn C Rowe, Cholsoon Jang, Laura Liu, Michele R Hacker, Julie S Rhee, John Mitchell, Feroze Mahmood, Philip Hess, Caitlin Farrell, Nicole Koulisis, Eliyahu V Khankin, Suzanne D Burke, Igor Tudorache, Johann Bauersachs, Federica del Monte, Denise Hilfiker-Kleiner, S Ananth Karumanchi, Zoltan Arany. Cardiac angiogenic imbalance leads to peripartum cardiomyopathy.
Nature.
2012 May; 485(7398):333-8. doi:
10.1038/nature11040. [PMID: 22596155] - Ariel Rokem, Ayelet N Landau, William Prinzmetal, Deanna L Wallace, Michael A Silver, Mark D'Esposito. Modulation of inhibition of return by the dopamine D2 receptor agonist bromocriptine depends on individual DAT1 genotype.
Cerebral cortex (New York, N.Y. : 1991).
2012 May; 22(5):1133-8. doi:
10.1093/cercor/bhr185. [PMID: 21799208] - V H Lyzogub, O V Dolynna, T V Bogdan, V O Sobol'. [State of the dopamine system activity, as one of factors for the development of arterial hypertension and obesity].
Likars'ka sprava.
2012 Apr; ?(3-4):41-7. doi:
NULL. [PMID: 23356136] - Elisabetta Esposito, Paolo Mariani, Laura Ravani, Catia Contado, Mattia Volta, Simone Bido, Markus Drechsler, Serena Mazzoni, Enea Menegatti, Michele Morari, Rita Cortesi. Nanoparticulate lipid dispersions for bromocriptine delivery: characterization and in vivo study.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.
2012 Feb; 80(2):306-14. doi:
10.1016/j.ejpb.2011.10.015. [PMID: 22061262] - V G Lyzogub, V O Sobol', O V Dolynna, L A Kuz'mins'ka. [Effect of combined treatment with dopamine receptor agonists and antagonists of aldosterone on the performance of daily blood pressure monitoring in patients with hypertension and concomitant obesity].
Likars'ka sprava.
2012 Jan; ?(1-2):63-8. doi:
. [PMID: 23035601] - Mieke van Holstein, Esther Aarts, Marieke E van der Schaaf, Dirk E M Geurts, Robbert J Verkes, Barbara Franke, Martine R van Schouwenburg, Roshan Cools. Human cognitive flexibility depends on dopamine D2 receptor signaling.
Psychopharmacology.
2011 Dec; 218(3):567-78. doi:
10.1007/s00213-011-2340-2. [PMID: 21611724] - Edwena D Miles, Yan Xue, James R Strickland, James A Boling, James C Matthews. Ergopeptines bromocriptine and ergovaline and the dopamine type-2 receptor inhibitor domperidone inhibit bovine equilibrative nucleoside transporter 1-like activity.
Journal of agricultural and food chemistry.
2011 Sep; 59(17):9691-9. doi:
10.1021/jf201713m. [PMID: 21790119] - Katarina Berinder, Thomas Nyström, Charlotte Höybye, Kerstin Hall, Anna-Lena Hulting. Insulin sensitivity and lipid profile in prolactinoma patients before and after normalization of prolactin by dopamine agonist therapy.
Pituitary.
2011 Sep; 14(3):199-207. doi:
10.1007/s11102-010-0277-9. [PMID: 21128120] - Michael C Rudolph, Tanya D Russell, Patricia Webb, Margaret C Neville, Steven M Anderson. Prolactin-mediated regulation of lipid biosynthesis genes in vivo in the lactating mammary epithelial cell.
American journal of physiology. Endocrinology and metabolism.
2011 Jun; 300(6):E1059-68. doi:
10.1152/ajpendo.00083.2011. [PMID: 21467304] - Pallavi Iyer, Mark E Molitch. Positive prolactin response to bromocriptine in 2 patients with cabergoline-resistant prolactinomas.
Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists.
2011 May; 17(3):e55-8. doi:
10.4158/ep10369.cr. [PMID: 21324816] - Cintia M dos Santos Silva, Flavia R P Barbosa, Giovanna A B Lima, Leila Warszawski, Rosita Fontes, Romeu C Domingues, Mõnica R Gadelha. BMI and metabolic profile in patients with prolactinoma before and after treatment with dopamine agonists.
Obesity (Silver Spring, Md.).
2011 Apr; 19(4):800-5. doi:
10.1038/oby.2010.150. [PMID: 20559294] - Paraskevi Mediskou, Maria P Yavropoulou, Kaliopi Kotsa, Xanthi Tsekmekidou, Anna Psarakou-Gotzamani, Alexandra Papazisi, Anastasia Chlorou, John G Yovos. The renin-angiotensin-aldosterone axis in patients with nontumoral [corrected] hyperprolactinemia.
Clinical endocrinology.
2011 Mar; 74(3):306-11. doi:
10.1111/j.1365-2265.2010.03936.x. [PMID: 21114511] - Robert Krysiak, Agnieszka Kedzia, Bogusław Okopień. [The effect of oxcarbamazepine on the clinical effectiveness of dopamine agonists in the treatment of prolactinoma].
Wiadomosci lekarskie (Warsaw, Poland : 1960).
2011; 64(4):279-82. doi:
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The Cochrane database of systematic reviews.
2010 Dec; ?(12):CD007747. doi:
10.1002/14651858.cd007747.pub2. [PMID: 21154382] - Jessica L Kerr, Erin M Timpe, Katherine A Petkewicz. Bromocriptine mesylate for glycemic management in type 2 diabetes mellitus.
The Annals of pharmacotherapy.
2010 Nov; 44(11):1777-85. doi:
10.1345/aph.1p271. [PMID: 20978217] - Yasufumi Shirasaki, Masunobu Sugimura, Toshiyuki Sato. Bromocriptine, an ergot alkaloid, inhibits excitatory amino acid release mediated by glutamate transporter reversal.
European journal of pharmacology.
2010 Sep; 643(1):48-57. doi:
10.1016/j.ejphar.2010.06.007. [PMID: 20599932] - Takashi Abe, Izuki Amano, Rintaro Sawa, Shigeo Akira, Akihito Nakai, Toshiyuki Takeshita. Recovery from peripartum cardiomyopathy in a Japanese woman after administration of bromocriptine as a new treatment option.
Journal of Nippon Medical School = Nippon Ika Daigaku zasshi.
2010 Aug; 77(4):226-30. doi:
10.1272/jnms.77.226. [PMID: 20818143] - Zahra Heidari, Farhad Hosseinpanah, Nahid Shirazian. Achievement of fertility in an infertile man with resistant macroprolactinoma using high-dose bromocriptine and a combination of human chorionic gonadotropin and an aromatase inhibitor.
Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists.
2010 Jul; 16(4):669-72. doi:
10.4158/ep10026.cr. [PMID: 20439242]