(1S,2S)-(+)-1,2-Diaminocyclohexane (BioDeep_00000171974)

   

human metabolite blood metabolite Volatile Flavor Compounds


代谢物信息卡片


1,2-Cyclohexanediamine, (trans)-(S)-isomer

化学式: C6H14N2 (114.1156924)
中文名称: 1,2-环己二胺,顺反异构体混合物, 1,2-环己烷二胺
谱图信息: 最多检出来源 Homo sapiens(blood) 14.29%

分子结构信息

SMILES: C1CCC(C(C1)N)N
InChI: InChI=1S/C6H14N2/c7-5-3-1-2-4-6(5)8/h5-6H,1-4,7-8H2

描述信息

同义名列表

14 个代谢物同义名

1,2-Cyclohexanediamine, (trans)-(S)-isomer; 1,2-Cyclohexanediamine, (trans)-(R)-isomer; 1,2-Cyclohexanediamine, (trans)-isomer; 1,2-Cyclohexanediamine, (cis)-isomer; (1S,2S)-(+)-1,2-Diaminocyclohexane; trans-1,2-Cyclohexanediamine; trans-1,2-Diaminocyclohexane; Meso-1,2-diaminocyclohexane; Cyclohexane-1,2-diamine; 1,2-Diaminocyclohexane; 1,2-Cyclohexanediamine; 1,2-DACH; Dach; 1,2-Cyclohexanediamine



数据库引用编号

6 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Nayan Roy, Surjatapa Nath, Pradip C Paul, T Sanjoy Singh. Fluorescence Behavior of Schiff Base-N, N'-bis(salicylidene) Trans 1, 2-Diaminocyclohexane in Proteinous and Micellar Environments. Journal of fluorescence. 2017 Nov; 27(6):2295-2311. doi: 10.1007/s10895-017-2171-6. [PMID: 28831629]
  • Benjamin W J Harper, Aviva Friedman-Ezra, Roman Sirota, Emanuele Petruzzella, Janice R Aldrich-Wright, Dan Gibson. Probing the Interactions of Cytotoxic [Pt(1S,2S-DACH)(5,6-dimethyl-1,10-phenanthroline)] and Its PtIV Derivatives with Human Serum. ChemMedChem. 2017 04; 12(7):510-519. doi: 10.1002/cmdc.201700092. [PMID: 28206707]
  • Mehvash Zaki, Mohd Afzal, Musheer Ahmad, Sartaj Tabassum. Synthesis and crystal structure elucidation of new copper(II)-based chemotherapeutic agent coupled with 1,2-DACH and orthovanillin: Validated by in vitro DNA/HSA binding profile and pBR322 cleavage pathway. Journal of photochemistry and photobiology. B, Biology. 2016 Aug; 161(?):318-27. doi: 10.1016/j.jphotobiol.2016.05.030. [PMID: 27289445]
  • Said S Al-Jaroudi, Muhammad Altaf, Abdulaziz A Al-Saadi, Abdel-Nasser Kawde, Saleh Altuwaijri, Saeed Ahmad, Anvarhusein A Isab. Synthesis, characterization and theoretical calculations of (1,2-diaminocyclohexane)(1,3-diaminopropane)gold(III) chloride complexes: in vitro cytotoxic evaluations against human cancer cell lines. Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine. 2015 Oct; 28(5):827-44. doi: 10.1007/s10534-015-9869-1. [PMID: 26099502]
  • Amina Bouslimani, Nicole Bec, Matthias Glueckmann, Christophe Hirtz, Christian Larroque. Matrix-assisted laser desorption/ionization imaging mass spectrometry of oxaliplatin derivatives in heated intraoperative chemotherapy (HIPEC)-like treated rat kidney. Rapid communications in mass spectrometry : RCM. 2010 Feb; 24(4):415-21. doi: 10.1002/rcm.4408. [PMID: 20082287]
  • Ali Ouadi, Anthony Loussouarn, Laurence Morandeau, Patricia Remaud, Alain Faivre-Chauvet, John Webb, Jean-Francois Gestin. Influence of trans-1,2-diaminocyclohexane structure and mixed carboxylic/phosphonic group combinations on samarium-153 chelation capacity and stability. European journal of medicinal chemistry. 2004 May; 39(5):467-72. doi: 10.1016/j.ejmech.2004.02.009. [PMID: 15110973]
  • Ghada Nimeri, Lena Ohman, Hans Elwing, Jonas Wetterö, Torbjörn Bengtsson. The influence of plasma proteins and platelets on oxygen radical production and F-actin distribution in neutrophils adhering to polymer surfaces. Biomaterials. 2002 Apr; 23(8):1785-95. doi: 10.1016/s0142-9612(01)00305-2. [PMID: 11950049]
  • J Zou, X D Yang, F An, K Wang. Relationship between cellular uptake rate and chemical behavior of diammine/diaminocyclohexane platinum (II) complexes with oxygen-ligating anionic groups. Journal of inorganic biochemistry. 1998 Jul; 70(3-4):227-32. doi: 10.1016/s0162-0134(98)10020-x. [PMID: 9720308]
  • J Zou, X G Yang, R C Li, J F Lu, K Wang. The chirality selectivity in the uptake of platinum (II) complexes with 1,2-cyclohexanediamine isomers as carrier ligand by human erythrocytes. Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine. 1997 Jan; 10(1):37-43. doi: 10.1023/a:1018314719904. [PMID: 9002181]
  • G Nimeri, A Augustinsson, B Lassen, O Stendahl, L Ohman, H Elwing. The chemiluminescence response of neutrophils on polymer surfaces made by glow discharge plasma polymerization. Journal of biomaterials science. Polymer edition. 1994; 6(8):741-9. doi: 10.1163/156856295x00120. [PMID: 7703189]
  • R Perez-Soler, I Han, S al-Baker, A R Khokhar. Lipophilic platinum complexes entrapped in liposomes: improved stability and preserved antitumor activity with complexes containing linear alkyl carboxylato leaving groups. Cancer chemotherapy and pharmacology. 1994; 33(5):378-84. doi: 10.1007/bf00686266. [PMID: 8306411]
  • Y Kidani. [Development of antitumor platinum complexes]. Gan to kagaku ryoho. Cancer & chemotherapy. 1983 Dec; 10(12):2442-52. doi: NULL. [PMID: 6360050]
  • A A Faiers, A Y Loh, D H Osmond. Resolution of rat renin substrates by isoelectric focusing. Canadian journal of biochemistry. 1977 Aug; 55(8):869-75. doi: 10.1139/o77-128. [PMID: 19143]
  • D WATSON, J A ROGERS. Serum calcium determination with 1,2-diaminocyclohexane-N-tetra-acetate. Clinica chimica acta; international journal of clinical chemistry. 1963 Jan; 8(?):168-9. doi: 10.1016/0009-8981(63)90222-5. [PMID: 13999196]