Chloridazon (BioDeep_00000001148)

   

Industrial Pollutants


代谢物信息卡片


Chloridazon

化学式: C10H8ClN3O (221.0356)
中文名称: 5-氨基-4-氯-2-苯基-3(2H)-哒嗪酮, 灭幼脲
谱图信息: 最多检出来源 Viridiplantae(plant) 20.48%

分子结构信息

SMILES: C1=CC=C(C=C1)N2C(=O)C(=C(C=N2)N)Cl
InChI: InChI=1S/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2

描述信息

CONFIDENCE standard compound; EAWAG_UCHEM_ID 88
CONFIDENCE standard compound; INTERNAL_ID 281; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 6944; ORIGINAL_PRECURSOR_SCAN_NO 6942
CONFIDENCE standard compound; INTERNAL_ID 281; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3286; ORIGINAL_PRECURSOR_SCAN_NO 3284
CONFIDENCE standard compound; INTERNAL_ID 281; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3282; ORIGINAL_PRECURSOR_SCAN_NO 3279
CONFIDENCE standard compound; INTERNAL_ID 281; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3278; ORIGINAL_PRECURSOR_SCAN_NO 3275
CONFIDENCE standard compound; INTERNAL_ID 281; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 6929; ORIGINAL_PRECURSOR_SCAN_NO 6925
CONFIDENCE standard compound; INTERNAL_ID 281; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 6942; ORIGINAL_PRECURSOR_SCAN_NO 6938
CONFIDENCE standard compound; INTERNAL_ID 281; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 6890; ORIGINAL_PRECURSOR_SCAN_NO 6885
CONFIDENCE standard compound; INTERNAL_ID 281; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3352; ORIGINAL_PRECURSOR_SCAN_NO 3350
CONFIDENCE standard compound; INTERNAL_ID 281; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3282; ORIGINAL_PRECURSOR_SCAN_NO 3278
CONFIDENCE standard compound; INTERNAL_ID 281; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 6929; ORIGINAL_PRECURSOR_SCAN_NO 6927
CONFIDENCE standard compound; INTERNAL_ID 281; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 6909; ORIGINAL_PRECURSOR_SCAN_NO 6907
CONFIDENCE standard compound; INTERNAL_ID 281; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3278; ORIGINAL_PRECURSOR_SCAN_NO 3276
CONFIDENCE standard compound; INTERNAL_ID 3300
CONFIDENCE standard compound; INTERNAL_ID 4018
CONFIDENCE standard compound; INTERNAL_ID 2317
CONFIDENCE standard compound; INTERNAL_ID 8402

同义名列表

3 个代谢物同义名

Chloridazon; CLZ; Chloridazon



数据库引用编号

73 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 5 ALB, AZIN2, CAT, HPGDS, PPM1G
Peripheral membrane protein 1 FDXR
Nucleus 4 ALB, AZIN2, OMP, PPM1G
cytosol 5 ALB, AZIN2, CAT, HPGDS, OMP
dendrite 1 AZIN2
trans-Golgi network 1 AZIN2
centrosome 1 ALB
nucleoplasm 2 HPGDS, PPM1G
Lipid-anchor 1 PPM1G
Synapse 1 OMP
Golgi apparatus 1 ALB
mitochondrial inner membrane 1 FDXR
neuronal cell body 1 OMP
Membrane 4 AZIN2, CAT, PPM1G, TMEM131
axon 2 AZIN2, OMP
extracellular exosome 2 ALB, CAT
endoplasmic reticulum 1 ALB
extracellular space 1 ALB
perinuclear region of cytoplasm 1 AZIN2
mitochondrion 3 AZIN2, CAT, FDXR
protein-containing complex 2 ALB, CAT
intracellular membrane-bounded organelle 2 CAT, HPGDS
Single-pass type I membrane protein 1 TMEM131
Secreted 1 ALB
extracellular region 2 ALB, CAT
mitochondrial matrix 2 CAT, FDXR
anchoring junction 1 ALB
perikaryon 1 AZIN2
cytoplasmic vesicle 1 AZIN2
Mitochondrion inner membrane 1 FDXR
focal adhesion 1 CAT
cis-Golgi network 1 AZIN2
Peroxisome 1 CAT
Peroxisome matrix 1 CAT
peroxisomal matrix 1 CAT
peroxisomal membrane 1 CAT
ciliary basal body 1 ALB
centriole 1 ALB
spindle pole 1 ALB
blood microparticle 1 ALB
ficolin-1-rich granule lumen 1 CAT
secretory granule lumen 1 CAT
endoplasmic reticulum lumen 1 ALB
platelet alpha granule lumen 1 ALB
transport vesicle 1 AZIN2
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 AZIN2
endoplasmic reticulum-Golgi intermediate compartment 1 AZIN2
Golgi apparatus, cis-Golgi network 1 AZIN2
catalase complex 1 CAT
ciliary transition fiber 1 ALB
granular vesicle 1 AZIN2


文献列表

  • Sajjad Babaei, Danial Kahrizi, Iraj Nosratti, Naser Karimi, Elham Arkan, M B Tahir. Preparation and characterization of chloridazon-loaded alginate/chitosan nanocapsules. Cellular and molecular biology (Noisy-le-Grand, France). 2022 Mar; 68(3):34-42. doi: 10.14715/cmb/2022.68.3.5. [PMID: 35988172]
  • Jan Chabera, Alzbeta Stara, Jan Kubec, Milos Buric, Eliska Zuskova, Antonin Kouba, Josef Velisek. The effect of chronic exposure to chloridazon and its degradation product chloridazon-desphenyl on signal crayfish Pacifastacus leniusculus. Ecotoxicology and environmental safety. 2021 Jan; 208(?):111645. doi: 10.1016/j.ecoenv.2020.111645. [PMID: 33396165]
  • Nishikant Wase, Boqiang Tu, James W Allen, Paul N Black, Concetta C DiRusso. Identification and Metabolite Profiling of Chemical Activators of Lipid Accumulation in Green Algae. Plant physiology. 2017 Aug; 174(4):2146-2165. doi: 10.1104/pp.17.00433. [PMID: 28652262]
  • Elżbieta G Magnucka, Stanisław J Pietr, Arkadiusz Kozubek, Robert Zarnowski. Various effects of the photosystem II--inhibiting herbicides on 5-n-alkylresorcinol accumulation in rye seedlings. Pesticide biochemistry and physiology. 2014 Nov; 116(?):56-62. doi: 10.1016/j.pestbp.2014.09.015. [PMID: 25454521]
  • Wojciech Pokora, Zbigniew Tukaj. Induction time of Fe-SOD synthesis and activity determine different tolerance of two Desmodesmus (green algae) strains to chloridazon: a study with synchronized cultures. Pesticide biochemistry and physiology. 2013 Sep; 107(1):68-77. doi: 10.1016/j.pestbp.2013.05.007. [PMID: 25149238]
  • Joanna Bisewska, Emilia I Sarnowska, Zbigniew H Tukaj. Phytotoxicity and antioxidative enzymes of green microalga (Desmodesmus subspicatus) and duckweed (Lemna minor) exposed to herbicides MCPA, chloridazon and their mixtures. Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes. 2012 Sep; 47(8):814-22. doi: 10.1080/03601234.2012.676443. [PMID: 22575008]
  • Markus Godejohann, Jean-Daniel Berset, Daniel Muff. Non-targeted analysis of wastewater treatment plant effluents by high performance liquid chromatography-time slice-solid phase extraction-nuclear magnetic resonance/time-of-flight-mass spectrometry. Journal of chromatography. A. 2011 Dec; 1218(51):9202-9. doi: 10.1016/j.chroma.2011.10.051. [PMID: 22098937]
  • Stefan Tukaj, Joanna Bisewska, Katarzyna Roeske, Zbigniew Tukaj. Time- and dose-dependent induction of HSP70 in Lemna minor exposed to different environmental stressors. Bulletin of environmental contamination and toxicology. 2011 Sep; 87(3):226-30. doi: 10.1007/s00128-011-0339-3. [PMID: 21681399]
  • Mirjana Marković, Svjetlana Cupać, Rada Durović, Jelena Milinović, Petar Kljajić. Assessment of heavy metal and pesticide levels in soil and plant products from agricultural area of Belgrade, Serbia. Archives of environmental contamination and toxicology. 2010 Feb; 58(2):341-51. doi: 10.1007/s00244-009-9359-y. [PMID: 19603130]
  • Gianluigi Buttiglieri, Manuela Peschka, Tobias Frömel, Jutta Müller, Francesca Malpei, Peter Seel, Thomas P Knepper. Environmental occurrence and degradation of the herbicide n-chloridazon. Water research. 2009 Jun; 43(11):2865-73. doi: 10.1016/j.watres.2009.03.035. [PMID: 19401257]
  • C O'Mahony, V L Campbell, M S Al-Khayatt, D J Brull. Rhabdomyolysis with atorvastatin and fusidic acid. Postgraduate medical journal. 2008 Jun; 84(992):325-7. doi: 10.1136/pgmj.2007.064097. [PMID: 18644925]
  • Tukaj Zbigniew, Pokora Wojciech. Individual and combined effect of anthracene, cadmium, and chloridazone on growth and activity of SOD izoformes in three Scenedesmus species. Ecotoxicology and environmental safety. 2006 Nov; 65(3):323-31. doi: 10.1016/j.ecoenv.2005.12.001. [PMID: 16464497]
  • E Mechant, R Bulcke. Metamitron-resistant Chenopodium album from sugar beet: cross-resistance profile. Communications in agricultural and applied biological sciences. 2006; 71(3 Pt A):725-32. doi: . [PMID: 17390814]
  • M Suwalsky, M Benites, F Villena, B Norris, L Quevedo. The organochlorine herbicide chloridazon interacts with cell membranes. Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology. 1998 Jul; 120(1):29-35. doi: 10.1016/s0742-8413(98)90002-0. [PMID: 9827013]
  • X P Lee, T Kumazawa, K Sato. Rapid extraction and capillary gas chromatography for diazine herbicides in human body fluids. Forensic science international. 1995 Apr; 72(3):199-207. doi: 10.1016/0379-0738(95)01704-m. [PMID: 7750875]
  • R Weisshaar, F Lingens. The lipopolysaccharide of a chloridazon-degrading bacterium. European journal of biochemistry. 1983 Dec; 137(1-2):155-61. doi: 10.1111/j.1432-1033.1983.tb07809.x. [PMID: 6653551]
  • W O CASTER, O MICKELSEN, A KEYS. Influence of dietary and physical factors on the urinary excretion of thiamine and pyramin. Federation proceedings. 1948 Mar; 7(1 Pt 1):149. doi: NULL. [PMID: 18856436]
  • O MICKELSEN. The urinary excretion of thiamine, pyramin (the pyrimidine-like component of thiamine) and riboflavin by man in semistarvation. Federation proceedings. 1946; 5(1 Pt 2):73. doi: NULL. [PMID: 21022202]