7-Glutarylaminocephalosporanate (BioDeep_00000010822)

   


代谢物信息卡片


3-[(acetyloxy)methyl]-7-[(4-carboxybutanoyl)amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

化学式: C15H18N2O8S (386.07838280000004)
中文名称:
谱图信息: 最多检出来源 Viridiplantae(plant) 4.03%

分子结构信息

SMILES: CC(=O)OCC1=C(C(=O)O)N2C(=O)C(NC(=O)CCCC(=O)O)C2SC1
InChI: InChI=1S/C15H18N2O8S/c1-7(18)25-5-8-6-26-14-11(13(22)17(14)12(8)15(23)24)16-9(19)3-2-4-10(20)21/h11,14H,2-6H2,1H3,(H,16,19)(H,20,21)(H,23,24)/t11-,14-/m1/s1

描述信息

D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D002511 - Cephalosporins
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D047090 - beta-Lactams
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D007769 - Lactams

同义名列表

4 个代谢物同义名

(7R)-7-(4-Carboxybutanamido)cephalosporanate; Glutaryl-7-aminocephalosporanic acid; 7-Glutarylaminocephalosporanate; 3-[(acetyloxy)methyl]-7-[(4-carboxybutanoyl)amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid



数据库引用编号

10 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Wei Zhang, Yuan Liu, Huabao Zheng, Sheng Yang, Weihong Jiang. Improving the activity and stability of GL-7-ACA acylase CA130 by site-directed mutagenesis. Applied and environmental microbiology. 2005 Sep; 71(9):5290-6. doi: 10.1128/aem.71.9.5290-5296.2005. [PMID: 16151116]
  • Xiang Mao, Weiwu Wang, Weihong Jiang, Guo-Ping Zhao. His23beta and Glu455beta of the Pseudomonas sp. 130 glutaryl-7-amino cephalosporanic acid acylase are crucially important for efficient autoproteolysis and enzymatic catalysis. The protein journal. 2004 Apr; 23(3):197-204. doi: 10.1023/b:jopc.0000026415.96041.27. [PMID: 15200051]
  • Wei Zhang, Xi Huang, Guoping Zhao, Weihong Jiang. Affinity labeled glutaryl-7-amino cephalosporanic acid acylase C130 can hydrolyze the inhibitor during crystallization. Biochemical and biophysical research communications. 2004 Jan; 313(3):555-8. doi: 10.1016/j.bbrc.2003.11.154. [PMID: 14697226]
  • Songcheng Zhu, Yunliu Yang, Guoping Zhao, Weihong Jiang. A rapid and specific method to screen environmental microorganisms for cephalosporin acylase activity. Journal of microbiological methods. 2003 Jul; 54(1):131-5. doi: 10.1016/s0167-7012(03)00013-7. [PMID: 12732432]
  • Xi Huang, Rong Zeng, Xiaoming Ding, Xiang Mao, Yi Ding, Zihe Rao, Yong Xie, Weihong Jiang, Guoping Zhao. Affinity alkylation of the Trp-B4 residue of the beta -subunit of the glutaryl 7-aminocephalosporanic acid acylase of Pseudomonas sp. 130. The Journal of biological chemistry. 2002 Mar; 277(12):10256-64. doi: 10.1074/jbc.m108683200. [PMID: 11782466]
  • J Chen, T B Zhu, Y F Zhang, Y L Yang, R S Jiao. [Enzymatic conversion of cephalosporin C to glutaryl-7-aminocephalosporanic acid using whole cells of the yeast Trigonopsis variabilis FA10]. Sheng wu gong cheng xue bao = Chinese journal of biotechnology. 2001 Mar; 17(2):150-4. doi: . [PMID: 11411221]
  • J T Vicenzi, G J Hansen. Enzymatic oxidation of cephalosporin C using whole cells of the yeast Triginopsis variabilis within a "cross-flow filter-reactor". Enzyme and microbial technology. 1993 Apr; 15(4):281-5. doi: 10.1016/0141-0229(93)90150-z. [PMID: 7765298]
  • A Delaney, T J Gal. Hazards of anesthesia and operation in maple-syrup-urine disease. Anesthesiology. 1976 Jan; 44(1):83-6. doi: 10.1097/00000542-197601000-00023. [PMID: 931]