NCBI Taxonomy: 97398

Streptomyces abikoensis (ncbi_taxid: 97398)

found 47 associated metabolites at species taxonomy rank level.

Ancestor: Streptomyces

Child Taxonomies: none taxonomy data.

Indole-3-carboxaldehyde

1H-indole-3-carbaldehyde

C9H7NO (145.0528)


Indole-3-carboxaldehyde (IAld or I3A), also known as 3-formylindole or 3-indolealdehyde, belongs to the class of organic compounds known as indoles. Indoles are compounds containing an indole moiety, which consists of a pyrrole ring fused to benzene to form 2,3-benzopyrrole. In humans, I3A is a biologically active metabolite which acts as a receptor agonist at the aryl hydrocarbon receptor in intestinal immune cells. It stimulates the production of interleukin-22 which facilitates mucosal reactivity (PMID:27102537). I3A is a microbially derived tryptophan metabolite produced by Clostridium and Lactobacillus (PMID:30120222, 27102537). I3A has also been found in the urine of patients with untreated phenylketonuria (PMID:5073866). I3A has been detected, but not quantified, in several different foods, such as beans, Brussels sprouts, cucumbers, cereals and cereal products, and white cabbages. This could make I3A a potential biomarker for the consumption of these foods. Indole-3-carbaldehyde is a heteroarenecarbaldehyde that is indole in which the hydrogen at position 3 has been replaced by a formyl group. It has a role as a plant metabolite, a human xenobiotic metabolite, a bacterial metabolite and a marine metabolite. It is a heteroarenecarbaldehyde, an indole alkaloid and a member of indoles. Indole-3-carboxaldehyde is a natural product found in Euphorbia hirsuta, Derris ovalifolia, and other organisms with data available. A heteroarenecarbaldehyde that is indole in which the hydrogen at position 3 has been replaced by a formyl group. Found in barley and tomato seedlings and cotton Indole-3-carboxaldehyde. CAS Common Chemistry. CAS, a division of the American Chemical Society, n.d. https://commonchemistry.cas.org/detail?cas_rn=487-89-8 (retrieved 2024-07-02) (CAS RN: 487-89-8). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0). Indole-3-carboxaldehyde (3-Formylindole), a banlangen extract, is the product of the oxidative degradation of indole-3-acetic acid (IAA) by crude enzyme preparations from etiolated pea seedlings. Indole-3-carboxaldehyde (3-Formylindole) is a biochemical used to prepare analogs of the indole phytoalexin cyclobrassinin[1]. Indole-3-carboxaldehyde (3-Formylindole), a banlangen extract, is the product of the oxidative degradation of indole-3-acetic acid (IAA) by crude enzyme preparations from etiolated pea seedlings. Indole-3-carboxaldehyde (3-Formylindole) is a biochemical used to prepare analogs of the indole phytoalexin cyclobrassinin[1].

   

Indole-3-carboxylic acid

1H-Indole-3-carboxylic acid

C9H7NO2 (161.0477)


Indole-3-carboxylic acid, also known as 3-carboxyindole or 3-indolecarboxylate, belongs to the class of organic compounds known as indolecarboxylic acids and derivatives. Indolecarboxylic acids and derivatives are compounds containing a carboxylic acid group (or a derivative thereof) linked to an indole. Naphthylmethylindoles: Any compound containing a 1H-indol-3-yl-(1-naphthyl)methane structure with substitution at the nitrogen atom of the indole ring by an alkyl, haloalkyl, alkenyl, cycloalkylmethyl, cycloalkylethyl, 1-(N-methyl-2-piperidinyl)methyl, or 2-(4-morpholinyl)ethyl group whether or not further substituted in the indole ring to any extent and whether or not substituted in the naphthyl ring to any extent. One example given is JWH-250. Outside of the human body, indole-3-carboxylic acid has been detected, but not quantified in several different foods, such as brassicas, broccoli, pulses, common beets, and barley. This could make indole-3-carboxylic acid a potential biomarker for the consumption of these foods. Notice the pentyl group substituted onto the nitrogen atom of the indole ring. Note that this definition encompasses only those compounds that have OH groups attached to both the phenyl and the cyclohexyl rings, and so does not include compounds such as O-1871 which lacks the cyclohexyl OH group, or compounds such as JWH-337 or JWH-344 which lack the phenolic OH group. Present in plants, e.g. apple (Pyrus malus), garden pea (Pisum sativum) and brassicas Indole-3-carboxylic acid is a normal urinary indolic tryptophan metabolite and has been found elevated in patients with liver diseases[1][2]. Indole-3-carboxylic acid is a normal urinary indolic tryptophan metabolite and has been found elevated in patients with liver diseases[1][2].

   

2-Phenylacetamide

2-phenylacetamide

C8H9NO (135.0684)


2-Phenylacetamide is an intermediate in phenylalanine metabolism and styrene degradation(KEGG ID C02505). It is the third to last step in the synthesis of phenylacetylglutamine and is converted from phenylalanine via the enzyme phenylalanine 2-monooxygenase [EC:1.13.12.9]. It is then converted to phenylacetate via the enzyme amidase [EC:3.5.1.4]. [HMDB] 2-Phenylacetamide is an intermediate in phenylalanine metabolism and styrene degradation(KEGG ID C02505). It is the third to last step in the synthesis of phenylacetylglutamine and is converted from phenylalanine via the enzyme phenylalanine 2-monooxygenase [EC:1.13.12.9]. It is then converted to phenylacetate via the enzyme amidase [EC:3.5.1.4]. 2-Phenylacetamide is an endogenous metabolite.

   

Carbazomycin E

Carbazomycin E

C15H13NO3 (255.0895)


   

Carbazomycin F

Carbazomycin F

C16H15NO4 (285.1001)


   

1-hydroxy-3,6-dimethoxy-1,2-dimethyl-9H-carbazol-4-one

1-hydroxy-3,6-dimethoxy-1,2-dimethyl-9H-carbazol-4-one

C16H17NO4 (287.1158)


   

Pimprinethine

Pimprinethine

C13H12N2O (212.095)


   

1H-Indole-3-carboxylic acid

1H-Indole-3-carboxylic acid

C9H7NO2 (161.0477)


IPB_RECORD: 302; CONFIDENCE confident structure CONFIDENCE confident structure; IPB_RECORD: 302

   

3-Indolecarboxylic acid

Indole-3-carboxylic acid_120169

C9H7NO2 (161.0477)


An indole-3-carboxylic acid carrying a carboxy group at position 3. Acquisition and generation of the data is financially supported in part by CREST/JST. IPB_RECORD: 2301; CONFIDENCE confident structure Indole-3-carboxylic acid is a normal urinary indolic tryptophan metabolite and has been found elevated in patients with liver diseases[1][2]. Indole-3-carboxylic acid is a normal urinary indolic tryptophan metabolite and has been found elevated in patients with liver diseases[1][2].

   

Indole-3-carboxaldehyde

INDOLE-3-CARBOXYALDEHYDE

C9H7NO (145.0528)


Indole-3-carboxaldehyde (3-Formylindole), a banlangen extract, is the product of the oxidative degradation of indole-3-acetic acid (IAA) by crude enzyme preparations from etiolated pea seedlings. Indole-3-carboxaldehyde (3-Formylindole) is a biochemical used to prepare analogs of the indole phytoalexin cyclobrassinin[1]. Indole-3-carboxaldehyde (3-Formylindole), a banlangen extract, is the product of the oxidative degradation of indole-3-acetic acid (IAA) by crude enzyme preparations from etiolated pea seedlings. Indole-3-carboxaldehyde (3-Formylindole) is a biochemical used to prepare analogs of the indole phytoalexin cyclobrassinin[1].

   

2-PHENYLACETAMIDE

2-phenylacetamide

C8H9NO (135.0684)


A monocarboxylic acid amide that is acetamide substituted by a phenyl group at position 2. 2-Phenylacetamide is an endogenous metabolite.

   

Gancidin W

3-(2-methylpropyl)-octahydropyrrolo[1,2-a]piperazine-1,4-dione

C11H18N2O2 (210.1368)


Cyclo(L-Leu-L-Pro) is an inhibitory substance targeting to production of norsolorinic acid (NA,a precursor of aflatoxin),which can be isolated from A. xylosoxidans NFRI-A1. Cyclo(L-Leu-L-Pro) inhibits accumulation of NA by A. parasiticus NFRI-95 and inhibits spore formation. Cyclo(L-Leu-L-Pro) inhibits aflatoxin production with an IC50 of 0.2 mg/mL in A. parasiticus SYS-4[1].

   

771-50-6

InChI=1\C9H7NO2\c11-9(12)7-5-10-8-4-2-1-3-6(7)8\h1-5,10H,(H,11,12

C9H7NO2 (161.0477)


Indole-3-carboxylic acid is a normal urinary indolic tryptophan metabolite and has been found elevated in patients with liver diseases[1][2]. Indole-3-carboxylic acid is a normal urinary indolic tryptophan metabolite and has been found elevated in patients with liver diseases[1][2].

   

AI3-52407

5-21-08-00246 (Beilstein Handbook Reference)

C9H7NO (145.0528)


Indole-3-carboxaldehyde (3-Formylindole), a banlangen extract, is the product of the oxidative degradation of indole-3-acetic acid (IAA) by crude enzyme preparations from etiolated pea seedlings. Indole-3-carboxaldehyde (3-Formylindole) is a biochemical used to prepare analogs of the indole phytoalexin cyclobrassinin[1]. Indole-3-carboxaldehyde (3-Formylindole), a banlangen extract, is the product of the oxidative degradation of indole-3-acetic acid (IAA) by crude enzyme preparations from etiolated pea seedlings. Indole-3-carboxaldehyde (3-Formylindole) is a biochemical used to prepare analogs of the indole phytoalexin cyclobrassinin[1].

   

Strevertene A

Strevertene A

C31H48O10 (580.3247)


   

(6s,9s,14r,17r)-17-ethenyl-9,14-diisopropyl-6-(methoxymethyl)-10,14,17-trimethyl-2,7,10-triazatetracyclo[9.7.1.0⁴,¹⁹.0¹³,¹⁸]nonadeca-1(18),3,7,11(19),12-pentaen-8-ol

(6s,9s,14r,17r)-17-ethenyl-9,14-diisopropyl-6-(methoxymethyl)-10,14,17-trimethyl-2,7,10-triazatetracyclo[9.7.1.0⁴,¹⁹.0¹³,¹⁸]nonadeca-1(18),3,7,11(19),12-pentaen-8-ol

C29H43N3O2 (465.3355)


   

(1r,2r,3r)-3-hydroxy-1,2-dimethyl-1,2,3,9-tetrahydrocarbazol-4-one

(1r,2r,3r)-3-hydroxy-1,2-dimethyl-1,2,3,9-tetrahydrocarbazol-4-one

C14H15NO2 (229.1103)


   

1-hydroxy-3-(2-methylpropyl)-3h,6h,7h,8h,8ah-pyrrolo[1,2-a]pyrazin-4-one

1-hydroxy-3-(2-methylpropyl)-3h,6h,7h,8h,8ah-pyrrolo[1,2-a]pyrazin-4-one

C11H18N2O2 (210.1368)


   

(6s,9s,14r,17r)-17-ethenyl-6-(hydroxymethyl)-9,14-diisopropyl-10,14,17-trimethyl-2,7,10-triazatetracyclo[9.7.1.0⁴,¹⁹.0¹³,¹⁸]nonadeca-1(18),3,7,11(19),12-pentaen-8-ol

(6s,9s,14r,17r)-17-ethenyl-6-(hydroxymethyl)-9,14-diisopropyl-10,14,17-trimethyl-2,7,10-triazatetracyclo[9.7.1.0⁴,¹⁹.0¹³,¹⁸]nonadeca-1(18),3,7,11(19),12-pentaen-8-ol

C28H41N3O2 (451.3199)


   

(6s,9s,14s,17r)-17-ethenyl-9,14-diisopropyl-6-(methoxymethyl)-10,14,17-trimethyl-2,7,10-triazatetracyclo[9.7.1.0⁴,¹⁹.0¹³,¹⁸]nonadeca-1(18),3,7,11(19),12-pentaen-8-ol

(6s,9s,14s,17r)-17-ethenyl-9,14-diisopropyl-6-(methoxymethyl)-10,14,17-trimethyl-2,7,10-triazatetracyclo[9.7.1.0⁴,¹⁹.0¹³,¹⁸]nonadeca-1(18),3,7,11(19),12-pentaen-8-ol

C29H43N3O2 (465.3355)


   

(2s)-2-amino-n-(3,10-dioxohexadecyl)-n,3-dihydroxypropanamide

(2s)-2-amino-n-(3,10-dioxohexadecyl)-n,3-dihydroxypropanamide

C19H36N2O5 (372.2624)


   

3-methoxy-1-(methoxymethyl)-2-methyl-9h-carbazol-4-ol

3-methoxy-1-(methoxymethyl)-2-methyl-9h-carbazol-4-ol

C16H17NO3 (271.1208)


   

(2r)-2-amino-n,3-dihydroxy-n-[(14s)-14-methyl-3,10-dioxohexadecyl]propanamide

(2r)-2-amino-n,3-dihydroxy-n-[(14s)-14-methyl-3,10-dioxohexadecyl]propanamide

C20H38N2O5 (386.2781)


   

(2r,3s,4e,6e,8e,10e,12e,14r,15r,16r,18r,22s,24s,26s,27r)-14,16,18,22,24,26-hexahydroxy-2,3,27-trimethyl-28-oxo-1-oxacyclooctacosa-4,6,8,10,12-pentaene-15-carboxylic acid

(2r,3s,4e,6e,8e,10e,12e,14r,15r,16r,18r,22s,24s,26s,27r)-14,16,18,22,24,26-hexahydroxy-2,3,27-trimethyl-28-oxo-1-oxacyclooctacosa-4,6,8,10,12-pentaene-15-carboxylic acid

C31H48O10 (580.3247)


   

3,4,6-trimethoxy-1,2-dimethyl-9h-carbazole

3,4,6-trimethoxy-1,2-dimethyl-9h-carbazole

C17H19NO3 (285.1365)


   

14,16,18,22,24,26-hexahydroxy-2,3,27-trimethyl-28-oxo-1-oxacyclooctacosa-4,6,8,10,12-pentaene-15-carboxylic acid

14,16,18,22,24,26-hexahydroxy-2,3,27-trimethyl-28-oxo-1-oxacyclooctacosa-4,6,8,10,12-pentaene-15-carboxylic acid

C31H48O10 (580.3247)


   

3-(2-ethyl-1,3-oxazol-5-yl)-1h-indole

3-(2-ethyl-1,3-oxazol-5-yl)-1h-indole

C13H12N2O (212.095)


   

2-phenylethanimidic acid

2-phenylethanimidic acid

C8H9NO (135.0684)


   

(2s)-2-{[(2s,3r)-3-amino-1,2-dihydroxy-4-phenylbutylidene]amino}-4-methylpentanoic acid

(2s)-2-{[(2s,3r)-3-amino-1,2-dihydroxy-4-phenylbutylidene]amino}-4-methylpentanoic acid

C16H24N2O4 (308.1736)


   

(2r)-2-amino-n,3-dihydroxy-n-[(10s)-10-hydroxy-3-oxohexadecyl]propanamide

(2r)-2-amino-n,3-dihydroxy-n-[(10s)-10-hydroxy-3-oxohexadecyl]propanamide

C19H38N2O5 (374.2781)


   

3,4-dimethoxy-1,2,9-trimethylcarbazole

3,4-dimethoxy-1,2,9-trimethylcarbazole

C17H19NO2 (269.1416)


   

13-oxa-4,20-diazatetracyclo[12.2.2.2³,⁶.1⁸,¹²]henicosa-1(16),8,10,12(19),14,17-hexaen-11-ol

13-oxa-4,20-diazatetracyclo[12.2.2.2³,⁶.1⁸,¹²]henicosa-1(16),8,10,12(19),14,17-hexaen-11-ol

C18H20N2O2 (296.1525)


   

3-methoxy-1,2-dimethyl-9h-carbazol-4-ol

3-methoxy-1,2-dimethyl-9h-carbazol-4-ol

C15H15NO2 (241.1103)


   

(2s)-2-amino-n,3-dihydroxy-n-(10-hydroxy-3-oxopentadecyl)propanamide

(2s)-2-amino-n,3-dihydroxy-n-(10-hydroxy-3-oxopentadecyl)propanamide

C18H36N2O5 (360.2624)


   

(3r,4r)-4-{[(2r)-2-{[(3r,4r)-1,3-dihydroxy-4-{[(2r)-1-hydroxy-2-{[(2s)-1-hydroxy-2-[(1-hydroxybutylidene)amino]-3-methylbutylidene]amino}-3-methylbutylidene]amino}-6-methylheptylidene]amino}-1-hydroxypropylidene]amino}-3-hydroxy-6-methylheptanoic acid

(3r,4r)-4-{[(2r)-2-{[(3r,4r)-1,3-dihydroxy-4-{[(2r)-1-hydroxy-2-{[(2s)-1-hydroxy-2-[(1-hydroxybutylidene)amino]-3-methylbutylidene]amino}-3-methylbutylidene]amino}-6-methylheptylidene]amino}-1-hydroxypropylidene]amino}-3-hydroxy-6-methylheptanoic acid

C33H61N5O9 (671.4469)


   

1-hydroxy-3-methoxy-1,2-dimethyl-9h-carbazol-4-one

1-hydroxy-3-methoxy-1,2-dimethyl-9h-carbazol-4-one

C15H15NO3 (257.1052)


   

(3s,6s)-13-oxa-4,20-diazatetracyclo[12.2.2.2³,⁶.1⁸,¹²]henicosa-1(16),8,10,12(19),14,17-hexaen-11-ol

(3s,6s)-13-oxa-4,20-diazatetracyclo[12.2.2.2³,⁶.1⁸,¹²]henicosa-1(16),8,10,12(19),14,17-hexaen-11-ol

C18H20N2O2 (296.1525)


   

(2s)-2-amino-n,3-dihydroxy-n-(15-methyl-3,10-dioxohexadecyl)propanamide

(2s)-2-amino-n,3-dihydroxy-n-(15-methyl-3,10-dioxohexadecyl)propanamide

C20H38N2O5 (386.2781)


   

(2s)-2-amino-n,3-dihydroxy-n-(10-hydroxy-3-oxoheptadecyl)propanamide

(2s)-2-amino-n,3-dihydroxy-n-(10-hydroxy-3-oxoheptadecyl)propanamide

C20H40N2O5 (388.2937)


   

2-[(3-amino-1,2-dihydroxy-4-phenylbutylidene)amino]-4-methylpentanoic acid

2-[(3-amino-1,2-dihydroxy-4-phenylbutylidene)amino]-4-methylpentanoic acid

C16H24N2O4 (308.1736)


   

3,4-dimethoxy-1,2-dimethyl-9h-carbazole

3,4-dimethoxy-1,2-dimethyl-9h-carbazole

C16H17NO2 (255.1259)


   

(6s,9s,14r,17r)-17-tert-butyl-14-ethenyl-9-isopropyl-6-(methoxymethyl)-10,14-dimethyl-2,7,10-triazatetracyclo[9.7.1.0⁴,¹⁹.0¹³,¹⁸]nonadeca-1(18),3,7,11(19),12-pentaen-8-ol

(6s,9s,14r,17r)-17-tert-butyl-14-ethenyl-9-isopropyl-6-(methoxymethyl)-10,14-dimethyl-2,7,10-triazatetracyclo[9.7.1.0⁴,¹⁹.0¹³,¹⁸]nonadeca-1(18),3,7,11(19),12-pentaen-8-ol

C29H43N3O2 (465.3355)


   

4-hydroxy-3,6-dimethoxy-2-methyl-9h-carbazole-1-carbaldehyde

4-hydroxy-3,6-dimethoxy-2-methyl-9h-carbazole-1-carbaldehyde

C16H15NO4 (285.1001)


   

(1s)-1-hydroxy-3-methoxy-1,2-dimethyl-9h-carbazol-4-one

(1s)-1-hydroxy-3-methoxy-1,2-dimethyl-9h-carbazol-4-one

C15H15NO3 (257.1052)


   

4-hydroxy-3-methoxy-2-methyl-9h-carbazole-1-carbaldehyde

4-hydroxy-3-methoxy-2-methyl-9h-carbazole-1-carbaldehyde

C15H13NO3 (255.0895)


   

3,6-dimethoxy-1,2-dimethyl-9h-carbazol-4-ol

3,6-dimethoxy-1,2-dimethyl-9h-carbazol-4-ol

C16H17NO3 (271.1208)


   

(6s,9s,14r,17r)-14-ethenyl-9,17-diisopropyl-6-(methoxymethyl)-10,14,17-trimethyl-2,7,10-triazatetracyclo[9.7.1.0⁴,¹⁹.0¹³,¹⁸]nonadeca-1(18),3,7,11(19),12-pentaen-8-ol

(6s,9s,14r,17r)-14-ethenyl-9,17-diisopropyl-6-(methoxymethyl)-10,14,17-trimethyl-2,7,10-triazatetracyclo[9.7.1.0⁴,¹⁹.0¹³,¹⁸]nonadeca-1(18),3,7,11(19),12-pentaen-8-ol

C29H43N3O2 (465.3355)