Chemical Formula: C16H17NO4
Chemical Formula C16H17NO4
Found 85 metabolite its formula value is C16H17NO4
Lycorine
Lycorine is an indolizidine alkaloid that is 3,12-didehydrogalanthan substituted by hydroxy groups at positions and 2 and a methylenedioxy group across positions 9 and 10. Isolated from Crinum asiaticum, it has been shown to exhibit antimalarial activity. It has a role as a protein synthesis inhibitor, an antimalarial, a plant metabolite and an anticoronaviral agent. It derives from a hydride of a galanthan. Lycorine is a natural product found in Sternbergia clusiana, Pancratium trianthum, and other organisms with data available. Lycorine is a toxic crystalline alkaloid found in various Amaryllidaceae species, such as the cultivated bush lily (Clivia miniata), surprise lilies (Lycoris), and daffodils (Narcissus). It may be highly poisonous, or even lethal, when ingested in certain quantities. Symptoms of lycorine toxicity are vomiting, diarrhea, and convulsions. Lycorine, definition at mercksource.com Regardless, it is sometimes used medicinally, a reason why some groups may harvest the very popular Clivia miniata. An indolizidine alkaloid that is 3,12-didehydrogalanthan substituted by hydroxy groups at positions and 2 and a methylenedioxy group across positions 9 and 10. Isolated from Crinum asiaticum, it has been shown to exhibit antimalarial activity. relative retention time with respect to 9-anthracene Carboxylic Acid is 0.144 relative retention time with respect to 9-anthracene Carboxylic Acid is 0.136 relative retention time with respect to 9-anthracene Carboxylic Acid is 0.138 CONFIDENCE Reference Standard (Level 1); INTERNAL_ID 2316 INTERNAL_ID 2316; CONFIDENCE Reference Standard (Level 1) [Raw Data] CBA60_Lycorine_pos_30eV.txt [Raw Data] CBA60_Lycorine_pos_10eV.txt [Raw Data] CBA60_Lycorine_pos_50eV.txt [Raw Data] CBA60_Lycorine_pos_40eV.txt [Raw Data] CBA60_Lycorine_pos_20eV.txt Lycorine is a natural alkaloid extracted from the Amaryllidaceae plant. Lycorine is a potent and orally active SCAP inhibitor with a Kd value 15.24 nM. Lycorine downregulates the SCAP protein level without changing its transcription[2]. Lycorine is also a melanoma vasculogenic inhibitor[3]. Lycorine can be used for the study of prostate cancer and metabolic diseases[2]. Lycorine is a natural alkaloid extracted from the Amaryllidaceae plant. Lycorine is a potent and orally active SCAP inhibitor with a Kd value 15.24 nM. Lycorine downregulates the SCAP protein level without changing its transcription[2]. Lycorine is also a melanoma vasculogenic inhibitor[3]. Lycorine can be used for the study of prostate cancer and metabolic diseases[2]. Lycorine is a natural alkaloid extracted from the Amaryllidaceae plant. Lycorine is a potent and orally active SCAP inhibitor with a Kd value 15.24 nM. Lycorine downregulates the SCAP protein level without changing its transcription[2]. Lycorine is also a melanoma vasculogenic inhibitor[3]. Lycorine can be used for the study of prostate cancer and metabolic diseases[2].
Norlaudanosoline
C16H17NO4 (287.11575220000003)
Norlaudanosoline (CAS: 4747-99-3), also known as tetrahydropapaveroline, belongs to the class of organic compounds known as benzylisoquinolines. These are organic compounds containing an isoquinoline to which a benzyl group is attached. Norlaudanosoline is a very strong basic compound (based on its pKa). Norlaundanosoline is a key intermediate in the synthesis of the benzylisoquinoline alkaloids, providing the upper isoquinoline portion of the morphinan skeleton. It is involved in alkaloid biosynthesis and is synthesized by the enzyme (S)-norlaudanosoline synthase. Formerly believed to be a biosynthetic precursor of morphine in Papaver somniferum, now disproved
norlaudanosoline
C16H17NO4 (287.11575220000003)
Origin: Animal; SubCategory_DNP: Isoquinoline alkaloids, Benzylisoquinoline alkaloids relative retention time with respect to 9-anthracene Carboxylic Acid is 0.055 relative retention time with respect to 9-anthracene Carboxylic Acid is 0.054 relative retention time with respect to 9-anthracene Carboxylic Acid is 0.053 Acquisition and generation of the data is financially supported by the Max-Planck-Society IPB_RECORD: 2522; CONFIDENCE confident structure
noroxymorphone
C16H17NO4 (287.11575220000003)
noroxymorphone is a metabolite of oxymorphone. Oxymorphone (Opana, Numorphan, Numorphone) or 14-Hydroxydihydromorphinone is a powerful semi-synthetic opioid analgesic first developed in Germany in 1914, patented in the USA by Endo Pharmaceuticals in 1955 and introduced to the United States market in January 1959 and other countries around the same time. It (along with hydromorphone) was designed to have less incidence of side effects than morphine and heroin. (Wikipedia) D002492 - Central Nervous System Depressants > D009294 - Narcotics > D053610 - Opiate Alkaloids C78272 - Agent Affecting Nervous System > C67413 - Opioid Receptor Agonist
Pipermethystine
C16H17NO4 (287.11575220000003)
Pipermethystine is found in beverages. Pipermethystine is an alkaloid from the leaves of kava (Piper methysticum). FDA advises against use of kava in food due to potential risk of severe liver damage (2002) Pipermethystine is an alkaloid present in the aerial (aboveground) portions of the kava plant. Alkaloid from the leaves of kava (Piper methysticum). FDA advises against use of kava in food due to potential risk of severe liver damage (2002)
lycorine
C16H17NO4 (287.11575220000003)
Riparin III
C16H17NO4 (287.11575220000003)
1-hydroxy-3,6-dimethoxy-1,2-dimethyl-9H-carbazol-4-one
C16H17NO4 (287.11575220000003)
(S)-2-(3,4-dihydroxybenzoylamino)-3-phenylpropanol|nigerrimin A
C16H17NO4 (287.11575220000003)
3-Isopentenyl-4-methoxy-7,8-methylendioxy-2-chinolon|6-methoxy-7-(3-methyl-but-2-enyl)-9H-[1,3]dioxolo[4,5-h]quinolin-8-one|6-methoxy-7-(3-methylbut-2-enyl)-1,3-dioxolo<4,5-h>quinolin-8-one
C16H17NO4 (287.11575220000003)
C16H17NO4_6,11-Methano-6H-benzo[b]-1,3-benzodioxolo[5,6-e]azepine-8,9-diol, 5,6a,7,8,9,11-hexahydro
C16H17NO4 (287.11575220000003)
noroxymorphone
C16H17NO4 (287.11575220000003)
D002492 - Central Nervous System Depressants > D009294 - Narcotics > D053610 - Opiate Alkaloids C78272 - Agent Affecting Nervous System > C67413 - Opioid Receptor Agonist
Pipermethystine
C16H17NO4 (287.11575220000003)
Benzamide, N-[(4-hydroxyphenyl)methyl]-3,4-dimethoxy
C16H17NO4 (287.11575220000003)
AMINO-(4-BENZYLOXY-3-METHOXY-PHENYL)-ACETIC ACID
C16H17NO4 (287.11575220000003)
Methyl 4-acetoxy-6-(dimethylamino)-2-naphthoate
C16H17NO4 (287.11575220000003)
diethyl 6-methylquinoline-2,3-dicarboxylate
C16H17NO4 (287.11575220000003)
Methyl 4-hydroxy-6-(4-morpholinyl)-2-naphthoate
C16H17NO4 (287.11575220000003)
5-Morpholin-4-ylmethyl-2-phenyl-furan-3-carboxylicacid
C16H17NO4 (287.11575220000003)
8-METHYL-QUINOLINE-2,3-DICARBOXYLIC ACID DIETHYL ESTER
C16H17NO4 (287.11575220000003)
ethyl 2-(2-ethoxy-2-oxoethyl)quinoline-3-carboxylate
C16H17NO4 (287.11575220000003)
3-((tert-Butoxycarbonyl)amino)-2-naphthoic acid
C16H17NO4 (287.11575220000003)
Methyl 2-amino-4-methoxy-5-(phenylmethoxy)benzoate
C16H17NO4 (287.11575220000003)
Methyl 2-amino-4-benzyloxy-5-methoxybenzoate
C16H17NO4 (287.11575220000003)
2-[4-(3-FORMYL-2,5-DIMETHYL-1H-1-PYRROLYL)PHENOXY]PROPANOIC ACID
C16H17NO4 (287.11575220000003)
N-(3,5-Dimethoxyphenyl)-4-methoxybenzamide
C16H17NO4 (287.11575220000003)
(4S)-(-)-T-BUTYLDIMETHYLSILOXY-2-CYCLOPENTEN-1-ONE
C16H17NO4 (287.11575220000003)
2,6-Dihydroxy-N-(2-(4-methoxyphenyl)ethyl)benzamide
C16H17NO4 (287.11575220000003)
1H-Pyrrole-1-acetic acid, 3-(ethoxycarbonyl)-2-methyl-5-phenyl-
C16H17NO4 (287.11575220000003)
N-(3,4-dimethoxyphenyl)-4-methoxybenzamide
C16H17NO4 (287.11575220000003)
2-(4-methoxyphenoxy)-N-(2-methoxyphenyl)acetamide
C16H17NO4 (287.11575220000003)
4-(5-(1,3-Benzodioxol-5-yl)-1-oxo-2,4-pentadienyl)morpholine
C16H17NO4 (287.11575220000003)
(4S)-4-(2-Naphthylmethyl)-D-glutamic acid
C16H17NO4 (287.11575220000003)
N-(2,3-dihydro-1,4-benzodioxin-3-ylmethyl)-5-ethyl-2-furancarboxamide
C16H17NO4 (287.11575220000003)
(17S,18S)-5,7-Dioxa-12-azapentacyclo[10.6.1.02,10.04,8.015,19]nonadeca-2,4(8),9,15-tetraene-17,18-diol
C16H17NO4 (287.11575220000003)
2-[(4,4-Dimethyl-2,6-dioxocyclohexyl)methylideneamino]benzoic acid
C16H17NO4 (287.11575220000003)
4-Ethoxycarbonylmethyl-3-methyl-1-para-tolyl-3-pyrroline-2,5-dione
C16H17NO4 (287.11575220000003)
4-hydroxy-3-(1-{[2-(4-hydroxyphenyl)ethyl]imino}ethyl)-6-methylpyran-2-one
C16H17NO4 (287.11575220000003)
(3r)-6-oxo-1-(3-phenylpropanoyl)-2,3-dihydropyridin-3-yl acetate
C16H17NO4 (287.11575220000003)
8-hydroxy-7-methoxy-2,2,6-trimethylpyrano[3,2-c]quinolin-5-one
C16H17NO4 (287.11575220000003)
(1s,17s,18s,19r)-5,7-dioxa-12-azapentacyclo[10.6.1.0²,¹⁰.0⁴,⁸.0¹⁵,¹⁹]nonadeca-2,4(8),9,15-tetraene-17,18-diol
C16H17NO4 (287.11575220000003)
(1s,7s,16r)-16-methoxy-5-oxa-10-azatetracyclo[8.7.0.0¹,¹³.0²,⁷]heptadeca-2,12,14-triene-4,11-dione
C16H17NO4 (287.11575220000003)
1-[(2e)-3-(3,4-dimethoxyphenyl)prop-2-enoyl]-5,6-dihydropyridin-2-one
C16H17NO4 (287.11575220000003)
(3z)-3-(1-{[2-(4-hydroxyphenyl)ethyl]amino}ethylidene)-6-methylpyran-2,4-dione
C16H17NO4 (287.11575220000003)
5,7,20,21-tetraoxa-14-azahexacyclo[16.2.1.0²,¹⁰.0⁴,⁸.0¹¹,¹⁵.0¹¹,¹⁹]henicosa-2(10),3,8-triene
C16H17NO4 (287.11575220000003)
n-[1-(4-methoxy-6-oxopyran-2-yl)-2-phenylethyl]ethanimidic acid
C16H17NO4 (287.11575220000003)
(1r,13s,15s,18r)-5,7-dioxa-12-azapentacyclo[10.6.1.0²,¹⁰.0⁴,⁸.0¹³,¹⁸]nonadeca-2,4(8),9,16-tetraene-15,18-diol
C16H17NO4 (287.11575220000003)
(1s,7r,16r)-16-methoxy-5-oxa-10-azatetracyclo[8.7.0.0¹,¹³.0²,⁷]heptadeca-2,12,14-triene-4,11-dione
C16H17NO4 (287.11575220000003)
16-methoxy-5-oxa-10-azatetracyclo[8.7.0.0¹,¹³.0²,⁷]heptadeca-2(7),12,14-triene-4,9-dione
C16H17NO4 (287.11575220000003)
16-methoxy-5-oxa-10-azatetracyclo[8.7.0.0¹,¹³.0²,⁷]heptadeca-2,12,14-triene-4,11-dione
C16H17NO4 (287.11575220000003)
5,7-dioxa-12-azapentacyclo[10.5.2.0¹,¹³.0²,¹⁰.0⁴,⁸]nonadeca-2,4(8),9,16-tetraene-15,18-diol
C16H17NO4 (287.11575220000003)
(1s,16r)-16-methoxy-5-oxa-10-azatetracyclo[8.7.0.0¹,¹³.0²,⁷]heptadeca-2(7),12,14-triene-4,11-dione
C16H17NO4 (287.11575220000003)
16-methoxy-5-oxa-10-azatetracyclo[8.7.0.0¹,¹³.0²,⁷]heptadeca-2,12,14-triene-4,9-dione
C16H17NO4 (287.11575220000003)
(1r,13s,15r,18s)-5,7-dioxa-12-azapentacyclo[10.5.2.0¹,¹³.0²,¹⁰.0⁴,⁸]nonadeca-2,4(8),9,16-tetraene-15,18-diol
C16H17NO4 (287.11575220000003)