Chemical Formula: C16H17NO4

Chemical Formula C16H17NO4

Found 85 metabolite its formula value is C16H17NO4

Lycorine

1H-[1,3]Dioxolo[4,5-j]pyrrolo[3,2,1-de]phenanthridine-1,2-diol, 2,4,5,7,12b,12c-hexahydro-, (1S,2S,12bS,12cS)-

C16H17NO4 (287.1157522)


Lycorine is an indolizidine alkaloid that is 3,12-didehydrogalanthan substituted by hydroxy groups at positions and 2 and a methylenedioxy group across positions 9 and 10. Isolated from Crinum asiaticum, it has been shown to exhibit antimalarial activity. It has a role as a protein synthesis inhibitor, an antimalarial, a plant metabolite and an anticoronaviral agent. It derives from a hydride of a galanthan. Lycorine is a natural product found in Sternbergia clusiana, Pancratium trianthum, and other organisms with data available. Lycorine is a toxic crystalline alkaloid found in various Amaryllidaceae species, such as the cultivated bush lily (Clivia miniata), surprise lilies (Lycoris), and daffodils (Narcissus). It may be highly poisonous, or even lethal, when ingested in certain quantities. Symptoms of lycorine toxicity are vomiting, diarrhea, and convulsions. Lycorine, definition at mercksource.com Regardless, it is sometimes used medicinally, a reason why some groups may harvest the very popular Clivia miniata. An indolizidine alkaloid that is 3,12-didehydrogalanthan substituted by hydroxy groups at positions and 2 and a methylenedioxy group across positions 9 and 10. Isolated from Crinum asiaticum, it has been shown to exhibit antimalarial activity. relative retention time with respect to 9-anthracene Carboxylic Acid is 0.144 relative retention time with respect to 9-anthracene Carboxylic Acid is 0.136 relative retention time with respect to 9-anthracene Carboxylic Acid is 0.138 CONFIDENCE Reference Standard (Level 1); INTERNAL_ID 2316 INTERNAL_ID 2316; CONFIDENCE Reference Standard (Level 1) [Raw Data] CBA60_Lycorine_pos_30eV.txt [Raw Data] CBA60_Lycorine_pos_10eV.txt [Raw Data] CBA60_Lycorine_pos_50eV.txt [Raw Data] CBA60_Lycorine_pos_40eV.txt [Raw Data] CBA60_Lycorine_pos_20eV.txt Lycorine is a natural alkaloid extracted from the Amaryllidaceae plant. Lycorine is a potent and orally active SCAP inhibitor with a Kd value 15.24 nM. Lycorine downregulates the SCAP protein level without changing its transcription[2]. Lycorine is also a melanoma vasculogenic inhibitor[3]. Lycorine can be used for the study of prostate cancer and metabolic diseases[2].
Lycorine is a natural alkaloid extracted from the Amaryllidaceae plant. Lycorine is a potent and orally active SCAP inhibitor with a Kd value 15.24 nM. Lycorine downregulates the SCAP protein level without changing its transcription[2]. Lycorine is also a melanoma vasculogenic inhibitor[3]. Lycorine can be used for the study of prostate cancer and metabolic diseases[2].
Lycorine is a natural alkaloid extracted from the Amaryllidaceae plant. Lycorine is a potent and orally active SCAP inhibitor with a Kd value 15.24 nM. Lycorine downregulates the SCAP protein level without changing its transcription[2]. Lycorine is also a melanoma vasculogenic inhibitor[3]. Lycorine can be used for the study of prostate cancer and metabolic diseases[2].

   

Norlaudanosoline

(1S)-1-[(3,4-dihydroxyphenyl)methyl]-1,2,3,4-tetrahydroisoquinoline-6,7-diol

C16H17NO4 (287.11575220000003)


Norlaudanosoline (CAS: 4747-99-3), also known as tetrahydropapaveroline, belongs to the class of organic compounds known as benzylisoquinolines. These are organic compounds containing an isoquinoline to which a benzyl group is attached. Norlaudanosoline is a very strong basic compound (based on its pKa). Norlaundanosoline is a key intermediate in the synthesis of the benzylisoquinoline alkaloids, providing the upper isoquinoline portion of the morphinan skeleton. It is involved in alkaloid biosynthesis and is synthesized by the enzyme (S)-norlaudanosoline synthase. Formerly believed to be a biosynthetic precursor of morphine in Papaver somniferum, now disproved

   

Hippagine

3alpha-Pancracine

C16H17NO4 (287.11575220000003)


   
   

Hamayne

Vittatine, 11-hydroxy-

C16H17NO4 (287.11575220000003)


   

norlaudanosoline

Tetrahydropapaveroline

C16H17NO4 (287.11575220000003)


Origin: Animal; SubCategory_DNP: Isoquinoline alkaloids, Benzylisoquinoline alkaloids relative retention time with respect to 9-anthracene Carboxylic Acid is 0.055 relative retention time with respect to 9-anthracene Carboxylic Acid is 0.054 relative retention time with respect to 9-anthracene Carboxylic Acid is 0.053 Acquisition and generation of the data is financially supported by the Max-Planck-Society IPB_RECORD: 2522; CONFIDENCE confident structure

   
   

CID 443694

11-Hydroxyvittatine

C16H17NO4 (287.11575220000003)


   

noroxymorphone

(1S,5R,13R,17S)-10,17-dihydroxy-12-oxa-4-azapentacyclo[9.6.1.0¹,¹³.0⁵,¹⁷.0⁷,¹⁸]octadeca-7(18),8,10-trien-14-one

C16H17NO4 (287.11575220000003)


noroxymorphone is a metabolite of oxymorphone. Oxymorphone (Opana, Numorphan, Numorphone) or 14-Hydroxydihydromorphinone is a powerful semi-synthetic opioid analgesic first developed in Germany in 1914, patented in the USA by Endo Pharmaceuticals in 1955 and introduced to the United States market in January 1959 and other countries around the same time. It (along with hydromorphone) was designed to have less incidence of side effects than morphine and heroin. (Wikipedia) D002492 - Central Nervous System Depressants > D009294 - Narcotics > D053610 - Opiate Alkaloids C78272 - Agent Affecting Nervous System > C67413 - Opioid Receptor Agonist

   

Pipermethystine

6-oxo-1-(3-Phenylpropanoyl)-1,2,3,6-tetrahydropyridin-3-yl acetic acid

C16H17NO4 (287.11575220000003)


Pipermethystine is found in beverages. Pipermethystine is an alkaloid from the leaves of kava (Piper methysticum). FDA advises against use of kava in food due to potential risk of severe liver damage (2002) Pipermethystine is an alkaloid present in the aerial (aboveground) portions of the kava plant. Alkaloid from the leaves of kava (Piper methysticum). FDA advises against use of kava in food due to potential risk of severe liver damage (2002)

   

lycorine

5,7-dioxa-12-azapentacyclo[10.6.1.0²,¹⁰.0⁴,⁸.0¹⁵,¹⁹]nonadeca-2,4(8),9,15-tetraene-17,18-diol

C16H17NO4 (287.11575220000003)


   

Riparin III

2,6-Dihydroxy-N-[2-(4-methoxyphenyl)ethyl]benzene-1-carboximidate

C16H17NO4 (287.11575220000003)


   
   
   
   
   
   

1-hydroxy-3,6-dimethoxy-1,2-dimethyl-9H-carbazol-4-one

1-hydroxy-3,6-dimethoxy-1,2-dimethyl-9H-carbazol-4-one

C16H17NO4 (287.11575220000003)


   
   
   
   
   
   

(S)-2-(3,4-dihydroxybenzoylamino)-3-phenylpropanol|nigerrimin A

(S)-2-(3,4-dihydroxybenzoylamino)-3-phenylpropanol|nigerrimin A

C16H17NO4 (287.11575220000003)


   

3-Isopentenyl-4-methoxy-7,8-methylendioxy-2-chinolon|6-methoxy-7-(3-methyl-but-2-enyl)-9H-[1,3]dioxolo[4,5-h]quinolin-8-one|6-methoxy-7-(3-methylbut-2-enyl)-1,3-dioxolo<4,5-h>quinolin-8-one

3-Isopentenyl-4-methoxy-7,8-methylendioxy-2-chinolon|6-methoxy-7-(3-methyl-but-2-enyl)-9H-[1,3]dioxolo[4,5-h]quinolin-8-one|6-methoxy-7-(3-methylbut-2-enyl)-1,3-dioxolo<4,5-h>quinolin-8-one

C16H17NO4 (287.11575220000003)


   
   

C16H17NO4_6,11-Methano-6H-benzo[b]-1,3-benzodioxolo[5,6-e]azepine-8,9-diol, 5,6a,7,8,9,11-hexahydro

NCGC00385948-01_C16H17NO4_6,11-Methano-6H-benzo[b]-1,3-benzodioxolo[5,6-e]azepine-8,9-diol, 5,6a,7,8,9,11-hexahydro-

C16H17NO4 (287.11575220000003)


   

Pyrophen

Pyrophen

C16H17NO4 (287.11575220000003)


CONFIDENCE Penicillium sp.

   

noroxymorphone

Nor Oxymorphone

C16H17NO4 (287.11575220000003)


D002492 - Central Nervous System Depressants > D009294 - Narcotics > D053610 - Opiate Alkaloids C78272 - Agent Affecting Nervous System > C67413 - Opioid Receptor Agonist

   

Pipermethystine

6-oxo-1-(3-phenylpropanoyl)-1,2,3,6-tetrahydropyridin-3-yl acetate

C16H17NO4 (287.11575220000003)


   

Benzamide, N-[(4-hydroxyphenyl)methyl]-3,4-dimethoxy

Benzamide, N-[(4-hydroxyphenyl)methyl]-3,4-dimethoxy

C16H17NO4 (287.11575220000003)


   

AMINO-(4-BENZYLOXY-3-METHOXY-PHENYL)-ACETIC ACID

AMINO-(4-BENZYLOXY-3-METHOXY-PHENYL)-ACETIC ACID

C16H17NO4 (287.11575220000003)


   

Methyl 4-acetoxy-6-(dimethylamino)-2-naphthoate

Methyl 4-acetoxy-6-(dimethylamino)-2-naphthoate

C16H17NO4 (287.11575220000003)


   

diethyl 6-methylquinoline-2,3-dicarboxylate

diethyl 6-methylquinoline-2,3-dicarboxylate

C16H17NO4 (287.11575220000003)


   

Methyl 4-hydroxy-6-(4-morpholinyl)-2-naphthoate

Methyl 4-hydroxy-6-(4-morpholinyl)-2-naphthoate

C16H17NO4 (287.11575220000003)


   

5-Morpholin-4-ylmethyl-2-phenyl-furan-3-carboxylicacid

5-Morpholin-4-ylmethyl-2-phenyl-furan-3-carboxylicacid

C16H17NO4 (287.11575220000003)


   
   
   

8-METHYL-QUINOLINE-2,3-DICARBOXYLIC ACID DIETHYL ESTER

8-METHYL-QUINOLINE-2,3-DICARBOXYLIC ACID DIETHYL ESTER

C16H17NO4 (287.11575220000003)


   

ethyl 2-(2-ethoxy-2-oxoethyl)quinoline-3-carboxylate

ethyl 2-(2-ethoxy-2-oxoethyl)quinoline-3-carboxylate

C16H17NO4 (287.11575220000003)


   

3-((tert-Butoxycarbonyl)amino)-2-naphthoic acid

3-((tert-Butoxycarbonyl)amino)-2-naphthoic acid

C16H17NO4 (287.11575220000003)


   

Methyl 2-amino-4-methoxy-5-(phenylmethoxy)benzoate

Methyl 2-amino-4-methoxy-5-(phenylmethoxy)benzoate

C16H17NO4 (287.11575220000003)


   

Methyl 2-amino-4-benzyloxy-5-methoxybenzoate

Methyl 2-amino-4-benzyloxy-5-methoxybenzoate

C16H17NO4 (287.11575220000003)


   

2-[4-(3-FORMYL-2,5-DIMETHYL-1H-1-PYRROLYL)PHENOXY]PROPANOIC ACID

2-[4-(3-FORMYL-2,5-DIMETHYL-1H-1-PYRROLYL)PHENOXY]PROPANOIC ACID

C16H17NO4 (287.11575220000003)


   

N-(3,5-Dimethoxyphenyl)-4-methoxybenzamide

N-(3,5-Dimethoxyphenyl)-4-methoxybenzamide

C16H17NO4 (287.11575220000003)


   

(4S)-(-)-T-BUTYLDIMETHYLSILOXY-2-CYCLOPENTEN-1-ONE

(4S)-(-)-T-BUTYLDIMETHYLSILOXY-2-CYCLOPENTEN-1-ONE

C16H17NO4 (287.11575220000003)


   

2,6-Dihydroxy-N-(2-(4-methoxyphenyl)ethyl)benzamide

2,6-Dihydroxy-N-(2-(4-methoxyphenyl)ethyl)benzamide

C16H17NO4 (287.11575220000003)


   

1H-Pyrrole-1-acetic acid, 3-(ethoxycarbonyl)-2-methyl-5-phenyl-

1H-Pyrrole-1-acetic acid, 3-(ethoxycarbonyl)-2-methyl-5-phenyl-

C16H17NO4 (287.11575220000003)


   

N-(3,4-dimethoxyphenyl)-4-methoxybenzamide

N-(3,4-dimethoxyphenyl)-4-methoxybenzamide

C16H17NO4 (287.11575220000003)


   

2-(4-methoxyphenoxy)-N-(2-methoxyphenyl)acetamide

2-(4-methoxyphenoxy)-N-(2-methoxyphenyl)acetamide

C16H17NO4 (287.11575220000003)


   

4-(5-(1,3-Benzodioxol-5-yl)-1-oxo-2,4-pentadienyl)morpholine

4-(5-(1,3-Benzodioxol-5-yl)-1-oxo-2,4-pentadienyl)morpholine

C16H17NO4 (287.11575220000003)


   

(4S)-4-(2-Naphthylmethyl)-D-glutamic acid

(4S)-4-(2-Naphthylmethyl)-D-glutamic acid

C16H17NO4 (287.11575220000003)


   
   

N-(2,3-dihydro-1,4-benzodioxin-3-ylmethyl)-5-ethyl-2-furancarboxamide

N-(2,3-dihydro-1,4-benzodioxin-3-ylmethyl)-5-ethyl-2-furancarboxamide

C16H17NO4 (287.11575220000003)


   

(17S,18S)-5,7-Dioxa-12-azapentacyclo[10.6.1.02,10.04,8.015,19]nonadeca-2,4(8),9,15-tetraene-17,18-diol

(17S,18S)-5,7-Dioxa-12-azapentacyclo[10.6.1.02,10.04,8.015,19]nonadeca-2,4(8),9,15-tetraene-17,18-diol

C16H17NO4 (287.11575220000003)


   

2-[(4,4-Dimethyl-2,6-dioxocyclohexyl)methylideneamino]benzoic acid

2-[(4,4-Dimethyl-2,6-dioxocyclohexyl)methylideneamino]benzoic acid

C16H17NO4 (287.11575220000003)


   

4-Ethoxycarbonylmethyl-3-methyl-1-para-tolyl-3-pyrroline-2,5-dione

4-Ethoxycarbonylmethyl-3-methyl-1-para-tolyl-3-pyrroline-2,5-dione

C16H17NO4 (287.11575220000003)


   
   

4-hydroxy-3-(1-{[2-(4-hydroxyphenyl)ethyl]imino}ethyl)-6-methylpyran-2-one

4-hydroxy-3-(1-{[2-(4-hydroxyphenyl)ethyl]imino}ethyl)-6-methylpyran-2-one

C16H17NO4 (287.11575220000003)


   

(3r)-6-oxo-1-(3-phenylpropanoyl)-2,3-dihydropyridin-3-yl acetate

(3r)-6-oxo-1-(3-phenylpropanoyl)-2,3-dihydropyridin-3-yl acetate

C16H17NO4 (287.11575220000003)


   

8-hydroxy-7-methoxy-2,2,6-trimethylpyrano[3,2-c]quinolin-5-one

8-hydroxy-7-methoxy-2,2,6-trimethylpyrano[3,2-c]quinolin-5-one

C16H17NO4 (287.11575220000003)


   

(1s,17s,18s,19r)-5,7-dioxa-12-azapentacyclo[10.6.1.0²,¹⁰.0⁴,⁸.0¹⁵,¹⁹]nonadeca-2,4(8),9,15-tetraene-17,18-diol

(1s,17s,18s,19r)-5,7-dioxa-12-azapentacyclo[10.6.1.0²,¹⁰.0⁴,⁸.0¹⁵,¹⁹]nonadeca-2,4(8),9,15-tetraene-17,18-diol

C16H17NO4 (287.11575220000003)


   

(1s,7s,16r)-16-methoxy-5-oxa-10-azatetracyclo[8.7.0.0¹,¹³.0²,⁷]heptadeca-2,12,14-triene-4,11-dione

(1s,7s,16r)-16-methoxy-5-oxa-10-azatetracyclo[8.7.0.0¹,¹³.0²,⁷]heptadeca-2,12,14-triene-4,11-dione

C16H17NO4 (287.11575220000003)


   

1-[(2e)-3-(3,4-dimethoxyphenyl)prop-2-enoyl]-5,6-dihydropyridin-2-one

1-[(2e)-3-(3,4-dimethoxyphenyl)prop-2-enoyl]-5,6-dihydropyridin-2-one

C16H17NO4 (287.11575220000003)


   

(3z)-3-(1-{[2-(4-hydroxyphenyl)ethyl]amino}ethylidene)-6-methylpyran-2,4-dione

(3z)-3-(1-{[2-(4-hydroxyphenyl)ethyl]amino}ethylidene)-6-methylpyran-2,4-dione

C16H17NO4 (287.11575220000003)


   

5,7,20,21-tetraoxa-14-azahexacyclo[16.2.1.0²,¹⁰.0⁴,⁸.0¹¹,¹⁵.0¹¹,¹⁹]henicosa-2(10),3,8-triene

5,7,20,21-tetraoxa-14-azahexacyclo[16.2.1.0²,¹⁰.0⁴,⁸.0¹¹,¹⁵.0¹¹,¹⁹]henicosa-2(10),3,8-triene

C16H17NO4 (287.11575220000003)


   

n-[1-(4-methoxy-6-oxopyran-2-yl)-2-phenylethyl]ethanimidic acid

n-[1-(4-methoxy-6-oxopyran-2-yl)-2-phenylethyl]ethanimidic acid

C16H17NO4 (287.11575220000003)


   

(1r,13s,15s,18r)-5,7-dioxa-12-azapentacyclo[10.6.1.0²,¹⁰.0⁴,⁸.0¹³,¹⁸]nonadeca-2,4(8),9,16-tetraene-15,18-diol

(1r,13s,15s,18r)-5,7-dioxa-12-azapentacyclo[10.6.1.0²,¹⁰.0⁴,⁸.0¹³,¹⁸]nonadeca-2,4(8),9,16-tetraene-15,18-diol

C16H17NO4 (287.11575220000003)


   

(1s,7r,16r)-16-methoxy-5-oxa-10-azatetracyclo[8.7.0.0¹,¹³.0²,⁷]heptadeca-2,12,14-triene-4,11-dione

(1s,7r,16r)-16-methoxy-5-oxa-10-azatetracyclo[8.7.0.0¹,¹³.0²,⁷]heptadeca-2,12,14-triene-4,11-dione

C16H17NO4 (287.11575220000003)


   

16-methoxy-5-oxa-10-azatetracyclo[8.7.0.0¹,¹³.0²,⁷]heptadeca-2(7),12,14-triene-4,9-dione

16-methoxy-5-oxa-10-azatetracyclo[8.7.0.0¹,¹³.0²,⁷]heptadeca-2(7),12,14-triene-4,9-dione

C16H17NO4 (287.11575220000003)


   

16-methoxy-5-oxa-10-azatetracyclo[8.7.0.0¹,¹³.0²,⁷]heptadeca-2,12,14-triene-4,11-dione

16-methoxy-5-oxa-10-azatetracyclo[8.7.0.0¹,¹³.0²,⁷]heptadeca-2,12,14-triene-4,11-dione

C16H17NO4 (287.11575220000003)


   

5,7-dioxa-12-azapentacyclo[10.5.2.0¹,¹³.0²,¹⁰.0⁴,⁸]nonadeca-2,4(8),9,16-tetraene-15,18-diol

5,7-dioxa-12-azapentacyclo[10.5.2.0¹,¹³.0²,¹⁰.0⁴,⁸]nonadeca-2,4(8),9,16-tetraene-15,18-diol

C16H17NO4 (287.11575220000003)


   

(1s,16r)-16-methoxy-5-oxa-10-azatetracyclo[8.7.0.0¹,¹³.0²,⁷]heptadeca-2(7),12,14-triene-4,11-dione

(1s,16r)-16-methoxy-5-oxa-10-azatetracyclo[8.7.0.0¹,¹³.0²,⁷]heptadeca-2(7),12,14-triene-4,11-dione

C16H17NO4 (287.11575220000003)


   

16-methoxy-5-oxa-10-azatetracyclo[8.7.0.0¹,¹³.0²,⁷]heptadeca-2,12,14-triene-4,9-dione

16-methoxy-5-oxa-10-azatetracyclo[8.7.0.0¹,¹³.0²,⁷]heptadeca-2,12,14-triene-4,9-dione

C16H17NO4 (287.11575220000003)


   

(1r,13s,15r,18s)-5,7-dioxa-12-azapentacyclo[10.5.2.0¹,¹³.0²,¹⁰.0⁴,⁸]nonadeca-2,4(8),9,16-tetraene-15,18-diol

(1r,13s,15r,18s)-5,7-dioxa-12-azapentacyclo[10.5.2.0¹,¹³.0²,¹⁰.0⁴,⁸]nonadeca-2,4(8),9,16-tetraene-15,18-diol

C16H17NO4 (287.11575220000003)