Gancidin W (BioDeep_00000618946)

PANOMIX_OTCML-2023

代谢物信息卡片

3-(2-methylpropyl)-octahydropyrrolo[1,2-a]piperazine-1,4-dione

化学式: C11H18N2O2 (210.1368)
中文名称: 环(L-脯氨酰-L-亮氨酰)
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC(C)CC1C(=O)N2CCCC2C(=O)N1
InChI: InChI=1S/C11H18N2O2/c1-7(2)6-8-11(15)13-5-3-4-9(13)10(14)12-8/h7-9H,3-6H2,1-2H3,(H,12,14)

描述信息

Cyclo(L-Leu-L-Pro) is an inhibitory substance targeting to production of norsolorinic acid (NA，a precursor of aflatoxin)，which can be isolated from A. xylosoxidans NFRI-A1. Cyclo(L-Leu-L-Pro) inhibits accumulation of NA by A. parasiticus NFRI-95 and inhibits spore formation. Cyclo(L-Leu-L-Pro) inhibits aflatoxin production with an IC50 of 0.2 mg/mL in A. parasiticus SYS-4[1].

同义名列表

37 个代谢物同义名

3-(2-methylpropyl)-octahydropyrrolo[1,2-a]piperazine-1,4-dione; 3-Isobutylhexahydropyrrolo[1,2-a]pyrazine-1,4-dione; L-Leucyl-L-proline lactam; L,L-Cyclo(leucylprolyl); L-Cyclo(leucyloprolyl); Cyclo(leucyl-prolyl); Cyclo-L-leu-L-pro; L-Cyclo(leu-pro); Cyclo(-leu-pro); Cyclo(leu-pro); Maculosin 6; Gancidin W; UNII-KQV8MY059B; Cyclo(L-prolyl-L-leucyl); Cyclo(L-Leu-L-Pro); (3S-trans)-Hexahydro-3-isobutylpyrrolo(1,2-a)pyrazine-1,4-dione; 3-(2-methylpropyl)-2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione; 3-(2-METHYLPROPYL)-HEXAHYDROPYRROLO[1,2-A]PYRAZINE-1,4-DIONE; 3-(2-methylpropyl)-octahydropyrrolo[1,2-a]pyrazine-1,4-dione; 3-isobutyl-2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione; 5-24-07-00347 (Beilstein Handbook Reference); ACon0_000484; ACon1_000716; cyclo-(R-Pro-R-Leu); cyclo-(R-prolyl-R-leucyl); Cyclo(leucyloprolyl); Cyclo(leucylprolyl); cyclo(Pro-Leu); Cyclo(Pro-Leu)Cyclo(leucyloprolyl); Cyclo(leucylprolyl); 3-(2-methylpropyl)-2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione; Cyclo(proline-leucine); cyclo(prolyl-leucyl); KQV8MY059B; Pyrrolo(1,2-a)pyrazine-1,4-dione, hexahydro-3-(2-methylpropyl)-; Pyrrolo(1,2-a)pyrazine-1,4-dione, hexahydro-3-(2-methylpropyl)-, (3S-trans)-; Pyrrolo(1,2-a)pyrazine-1,4-dione, hexahydro-3-isobutyl-, stereoisomer; Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro-3-(2-methylpropyl)-; SZJNCZMRZAUNQT-UHFFFAOYSA-N

数据库引用编号

7 个数据库交叉引用编号

PubChem: 102892
Metlin: METLIN89817
CAS: 5654-86-4
CAS: 2873-36-1
medchemexpress: HY-P1939
ChEBI: CHEBI:228605
MeSH: cyclo(prolyl-leucyl)

分类词条

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

17 个相关的物种来源信息

5599 - Alternaria alternata: 10.1073/PNAS.85.21.8008
746128 - Aspergillus fumigatus: 10.1128/AEM.70.12.7466-7473.2004
13443 - Coffea arabica: 10.1021/JF991256V
27314 - Dipodascus: 10.1007/BF01939910
1506160 - Penicillium cluniae: 10.1021/JF0530998
980945 - Plectris: 10.1248/CPB.43.1663
46147 - Portulaca oleracea: 10.1002/RCM.3526
317 - Pseudomonas syringae: 10.1021/NP020173X
97398 - Streptomyces abikoensis: 10.1248/CPB.32.354
68185 - Streptomyces chrestomyceticus: 10.2174/1568026618666180711154110
1428626 - Streptomyces malaysiense: 10.1038/SREP24247
92644 - Streptomyces malaysiensis: 10.1038/SREP24247
1827580 - Streptomyces nigra: 10.3389/FMICB.2018.01587
47716 - Streptomyces olivaceus: 10.3390/MD17080442
146923 - Streptomyces parvulus: 10.1556/030.63.2016.1.2
5543 - Trichoderma: 10.1248/CPB.43.1663
55601 - Vibrio anguillarum:

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位		关联基因列表