Exact Mass: 316.2878
Exact Mass Matches: 316.2878
Found 417 metabolites which its exact mass value is equals to given mass value 316.2878,
within given mass tolerance error 0.05 dalton. Try search metabolite list with more accurate mass tolerance error
0.01 dalton.
9,10-Dihydroxystearic acid
9,10-dihydroxystearic acid, also known as 9,10-dhsa or 9,10-dioh 18:0, is a member of the class of compounds known as long-chain fatty acids. Long-chain fatty acids are fatty acids with an aliphatic tail that contains between 13 and 21 carbon atoms. Thus, 9,10-dihydroxystearic acid is considered to be an octadecanoid lipid molecule. 9,10-dihydroxystearic acid is practically insoluble (in water) and a weakly acidic compound (based on its pKa). 9,10-dihydroxystearic acid can be found in peanut, which makes 9,10-dihydroxystearic acid a potential biomarker for the consumption of this food product. 9,10-dihydroxyoctadecanoic acid is a hydroxy-fatty acid formally derived from octacecanoic (stearic) acid by hydroxy substitution at positions 9 and 10. It is a dihydroxy monocarboxylic acid and a hydroxyoctadecanoic acid. It is a conjugate acid of a 9,10-dihydroxystearate. 9,10-Dihydroxystearic acid is a natural product found in Trypanosoma brucei and Apis cerana with data available.
Pregnenolone
Pregnenolone is a derivative of cholesterol, the product of cytochrome P450 side-chain cleavage (EC 1.14.15.6, CYP11A1. This reaction consists of three consecutive monooxygenations, a 22-hydroxylation, a 20-hydroxylation, and the cleavage of the C20-C22 bond, yielding pregnenolone. Pregnenolone is the precursor to gonadal steroid hormones and the adrenal corticosteroids. This reaction occurs in steroid hormone-producing tissues such as the adrenal cortex, corpus luteum, and placenta. The most notable difference between the placenta and other steroidogenic tissues is that electron supply to CYP11A1 limits the rate at which cholesterol is converted into pregnenolone in the placenta. The limiting component for electron delivery to CYP11A1 is the concentration of adrenodoxin reductase in the mitochondrial matrix which is insufficient to maintain the adrenodoxin pool in a fully reduced state. Pregnenolone is also a neurosteroid, and is produced in the spinal cord; CYP11A1 is the key enzyme catalyzing the conversion of cholesterol into pregnenolone, the rate-limiting step in the biosynthesis of all classes of steroids, and has been localized in sensory networks of the spinal cord dorsal horn. In the adrenal glomerulosa cell, angiotensin II, one of the major physiological regulators of mineralocorticoid synthesis, appears to affect most of the cholesterol transfer to the mitochondrial outer membrane and many steps in the transport to the inner membrane. Thus, it exerts a powerful control over the use of cholesterol for aldosterone production (PMID: 17222962, 15823613, 16632873, 15134809). C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C1636 - Therapeutic Steroid Hormone D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones COVID info from COVID-19 Disease Map Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS Pregnenolone (3β-Hydroxy-5-pregnen-20-one) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone can protect the brain from cannabis intoxication[1][2]. Pregnenolone is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels[3]. Pregnenolone (3β-Hydroxy-5-pregnen-20-one) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone can protect the brain from cannabis intoxication[1][2]. Pregnenolone is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels[3].
cannabigerol
A member of the class of resorcinols that is resorcinol which is substituted by a (2E)-3,7-dimethylocta-2,6-dien-1-yl group at position 2 and by a pentyl group at position 5. It is a natural product found in Cannabis sativa and Helichrysum species.
20alpha-Dihydroprogesterone
20alpha-Dihydroprogesterone is a biologically active 20-alpha-reduced metabolite of progesterone. It is converted from progesterone to 20-alpha-hydroxypregn-4-en-3-one by the 20-alpha-hydroxysteroid dehydrogenase in the corpus luteum and the placenta. Progesterone is a C-21 steroid hormone involved in the female menstrual cycle, pregnancy (supports gestation), and embryogenesis of humans and other species. Progesterone belongs to a class of hormones called progestagens, and is the major naturally occurring human progestagen (Wikipedia). During implantation and gestation, progesterone appears to decrease the maternal immune response to allow for the acceptance of the pregnancy. Progesterone decreases contractility of the uterine smooth muscle. The fetus metabolizes placental progesterone in the production of adrenal mineralo- and glucosteroids. A drop in progesterone levels is possibly one step that facilitates the onset of labour. In addition, progesterone inhibits lactation during pregnancy. The fall in progesterone levels following delivery is one of the triggers for milk production (Wikipedia). A biologically active 20-alpha-reduced metabolite of progesterone. It is converted from progesterone to 20-alpha-hydroxypregn-4-en-3-one by the 20-alpha-hydroxysteroid dehydrogenase in the corpus luteum and the placenta. -- Pubchem; Progesterone is a C-21 steroid hormone involved in the female menstrual cycle, pregnancy (supports gestation) and embryogenesis of humans and other species. Progesterone belongs to a class of hormones called progestagens, and is the major naturally occurring human progestagen. -- Wikipedia; During implantation and gestation, progesterone appears to decrease the maternal immune response to allow for the acceptance of the pregnancy. Progesterone decreases contractility of the uterine smooth muscle. The fetus metabolizes placental progesterone in the production of adrenal mineralo- and glucosteroids. A drop in progesterone levels is possibly one step that facilitates the onset of labor. In addition progesterone inhibits lactation during pregnancy. The fall in progesterone levels following delivery is one of the triggers for milk production. -- Wikipedia [HMDB] D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones > D011372 - Progestins
5a-Pregnane-3,20-dione
5a-Pregnane-3,20-dione is a biologically active 5-alpha-reduced metabolite of plasma progesterone. It is the immediate precursor of 5-alpha-pregnan-3-alpha-ol-20-one (allopregnanolone), a neuroactive steroid that binds with GABA(A) receptor. A biologically active 5-alpha-reduced metabolite of plasma progesterone. It is the immediate precursor of 5-alpha-pregnan-3-alpha-ol-20-one (allopregnanolone), a neuroactive steroid that binds with GABA(A) receptor. [HMDB] D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones 5a-Pregnane-3,20-dione is the endogenous progesterone metabolite.
Bolasterone
Bolasterone is an anabolic androgenic steroid. Analysis of steroids in urine has been used to detect different hormonal actions in human beings such as testicular function in men, hyperandrogenic disorders in women and puberty problems in children, by the measurement of anabolic steroids, and some hormonal disorders such as adrenocortical adenoma and Cushing syndrome by the control of corticoids. This steroid have been included in the International Olympic Committee (IOC) doping list due to their illegal use in some sports and in the list of schedules drugs in several countries because of its use by young people. In addition, the examination of endogenous steroids profile provides information about the health and the use of exogenous steroids. Bolasterone is excreted as the original compound in human urine. Androgenic anabolic steroids (AAS) are defined as natural, synthetic or semi-synthetic drugs chemicals derived from testosterone, used with the aim to improve physical performance by increasing both muscle strength and mass. Despite their reported toxicological effects on the cardiovascular, hepatic and neuro-endocrine systems, the AAS have been extensively used in sports activities. The use of anabolic steroids was banned by the International Olympic Committee for the first time at the Olympic Games in Montreal in 1976. Since that time the misuse of anabolic steroids by athletes has been controlled by analysis of urine of the excreted steroids or their metabolites, or both. (PMID: 10892583, 10932808, 14976846, 15042372, 15231229, 3308301, 8456050, 8674183, 16040239) [HMDB] Bolasterone is an anabolic androgenic steroid. Analysis of steroids in urine has been used to detect different hormonal actions in human beings such as testicular function in men, hyperandrogenic disorders in women and puberty problems in children, by the measurement of anabolic steroids, and some hormonal disorders such as adrenocortical adenoma and Cushing syndrome by the control of corticoids. This steroid have been included in the International Olympic Committee (IOC) doping list due to their illegal use in some sports and in the list of schedules drugs in several countries because of its use by young people. In addition, the examination of endogenous steroids profile provides information about the health and the use of exogenous steroids. Bolasterone is excreted as the original compound in human urine. Androgenic anabolic steroids (AAS) are defined as natural, synthetic or semi-synthetic drugs chemicals derived from testosterone, used with the aim to improve physical performance by increasing both muscle strength and mass. Despite their reported toxicological effects on the cardiovascular, hepatic and neuro-endocrine systems, the AAS have been extensively used in sports activities. The use of anabolic steroids was banned by the International Olympic Committee for the first time at the Olympic Games in Montreal in 1976. Since that time the misuse of anabolic steroids by athletes has been controlled by analysis of urine of the excreted steroids or their metabolites, or both. (PMID: 10892583, 10932808, 14976846, 15042372, 15231229, 3308301, 8456050, 8674183, 16040239). D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones > D045930 - Anabolic Agents C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C2360 - Anabolic Steroid Same as: D03144
6alpha,17alpha-Dimethyltestosterone
2alpha,17-Dimethyltestosterone
Norbolethone
Norbolethone is a 19-nor anabolic steroid first synthesized in 1966. During the 1960s it was administered to humans in efficacy studies concerned with short stature and underweight conditions. It has never been reported by doping control laboratories prior to 2001. Norbolethone was identified in two urine samples from one athlete by matching the mass spectra and chromatographic retention times with those of a reference standard. The samples also contained at least one likely metabolite. The samples were also unusual because the concentrations of endogenous steroids were exceptionally low. Since norbolethone is not known to be marketed by any pharmaceutical company, a clandestine source of norbolethone may exist. Norbolethone matches the description for what is described as a "designer steroid." Androgenic anabolic steroids (AAS) are defined as natural, synthetic or semi-synthetic drugs chemicals derived from testosterone, used with the aim to improve physical performance by increasing both muscle strength and mass. Despite their reported toxicological effects on the cardiovascular, hepatic and neuro-endocrine systems, the AAS have been extensively used in sports activities. (PMID: 12112254) [HMDB] Norbolethone is a 19-nor anabolic steroid first synthesized in 1966. During the 1960s it was administered to humans in efficacy studies concerned with short stature and underweight conditions. It has never been reported by doping control laboratories prior to 2001. Norbolethone was identified in two urine samples from one athlete by matching the mass spectra and chromatographic retention times with those of a reference standard. The samples also contained at least one likely metabolite. The samples were also unusual because the concentrations of endogenous steroids were exceptionally low. Since norbolethone is not known to be marketed by any pharmaceutical company, a clandestine source of norbolethone may exist. Norbolethone matches the description for what is described as a "designer steroid." Androgenic anabolic steroids (AAS) are defined as natural, synthetic or semi-synthetic drugs chemicals derived from testosterone, used with the aim to improve physical performance by increasing both muscle strength and mass. Despite their reported toxicological effects on the cardiovascular, hepatic and neuro-endocrine systems, the AAS have been extensively used in sports activities. (PMID: 12112254). C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C2360 - Anabolic Steroid
(9S,10S)-9,10-dihydroxyoctadecanoate
(9s,10s)-9,10-dihydroxyoctadecanoate is part of the Arachidonic acid metabolism, and Peroxisome pathways. It is a substrate for: Bifunctional epoxide hydrolase 2.
5-beta-pregnan-3,20 dione
(5beta)-pregnane-3,20-dione, also known as 3,20-pregnanedione or 5beta-dihydroprogesterone, belongs to gluco/mineralocorticoids, progestogins and derivatives class of compounds. Those are steroids with a structure based on a hydroxylated prostane moiety. Thus, (5beta)-pregnane-3,20-dione is considered to be a steroid lipid molecule (5beta)-pregnane-3,20-dione is practically insoluble (in water) and an extremely weak acidic compound (based on its pKa). (5beta)-pregnane-3,20-dione can be found in a number of food items such as opium poppy, walnut, rowal, and italian sweet red pepper, which makes (5beta)-pregnane-3,20-dione a potential biomarker for the consumption of these food products.
5-(8,11-Pentadecadienyl)-1,3-benzenediol
5-[(8Z,11Z)-pentadeca-8,11-dien-1-yl]benzene-1,3-diol is a member of resorcinols. 5-[(8Z,11Z)-pentadeca-8,11-dien-1-yl]benzene-1,3-diol is a natural product found in Merulius incarnatus, Anacardium occidentale, and Gloeostereum incarnatum with data available. 5-(8,11-Pentadecadienyl)-1,3-benzenediol is found in nuts. 5-(8,11-Pentadecadienyl)-1,3-benzenediol is isolated from Anacardium occidentale (cashew). Isolated from Anacardium occidentale (cashew). 5-(8,11-Pentadecadienyl)-1,3-benzenediol is found in nuts.
Kaurenoic acid methyl ester
Kaurenoic acid methyl ester is found in fats and oils. Kaurenoic acid methyl ester is isolated from Helianthus annuus (sunflower). Isolated from Helianthus annuus (sunflower). Kaurenoic acid methyl ester is found in fats and oils.
Calusterone
Calusterone is an androgenic steroid. Calusterone induce given orally induce a marked decrease (between 30 and 70\\% depending on the dose) in the binding capacity of oestradiol-17beta to specific uterine receptors in vivo. As an androgen, calusterone has been used as a therapeutic agent in postmenopausal women with metastatic breast cancer; the addition of a potent hormonal agent to effective cytotoxic chemotherapy improves the results of treatment of women with metastatic breast cancer. Calusterone is tested in sport screening; fast and sensitive method for the comprehensive screening of anabolic agents and other banned doping substances using gas chromatography/tandem mass spectrometry (GC/MS/MS) with an external ionization ion trap mass spectrometer have been developed for the parent substances and their metabolites. (PMID: 17610244, 12375280, 153787, 2325376, 12375280) [HMDB] Calusterone is an androgenic steroid. Calusterone induce given orally induce a marked decrease (between 30 and 70\\% depending on the dose) in the binding capacity of oestradiol-17beta to specific uterine receptors in vivo. As an androgen, calusterone has been used as a therapeutic agent in postmenopausal women with metastatic breast cancer; the addition of a potent hormonal agent to effective cytotoxic chemotherapy improves the results of treatment of women with metastatic breast cancer. Calusterone is tested in sport screening; fast and sensitive method for the comprehensive screening of anabolic agents and other banned doping substances using gas chromatography/tandem mass spectrometry (GC/MS/MS) with an external ionization ion trap mass spectrometer have been developed for the parent substances and their metabolites. (PMID: 17610244, 12375280, 153787, 2325376, 12375280). D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones > D045930 - Anabolic Agents C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C1636 - Therapeutic Steroid Hormone C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C2360 - Anabolic Steroid Same as: D03144
MG(15:0/0:0/0:0)
MG(15:0/0:0/0:0) is a monoacylglyceride. A monoglyceride, more correctly known as a monoacylglycerol, is a glyceride consisting of one fatty acid chain covalently bonded to a glycerol molecule through an ester linkage. Monoacylglycerol can be broadly divided into two groups; 1-monoacylglycerols (or 3-monoacylglycerols) and 2-monoacylglycerols, depending on the position of the ester bond on the glycerol moiety. Normally the 1-/3-isomers are not distinguished from each other and are termed alpha-monoacylglycerols, while the 2-isomers are beta-monoacylglycerols. Monoacylglycerols are formed biochemically via release of a fatty acid from diacylglycerol by diacylglycerol lipase or hormone sensitive lipase. Monoacylglycerols are broken down by monoacylglycerol lipase. They tend to be minor components only of most plant and animal tissues, and indeed would not be expected to accumulate because their strong detergent properties would have a disruptive effect on membranes. 2-Monoacylglycerols are a major end product of the intestinal digestion of dietary fats in animals via the enzyme pancreatic lipase. They are taken up directly by the intestinal cells and converted to triacylglycerols via the monoacylglycerol pathway before being transported in lymph to the liver. Mono- and Diglycerides are commonly added to commercial food products in small quantities. They act as emulsifiers, helping to mix ingredients such as oil and water that would not otherwise blend well. MG(15:0/0:0/0:0) belongs to the family of monoradyglycerols, which are glycerolipids lipids containing a common glycerol backbone to which at one fatty acyl group is attached. Their general formula is [R1]OCC(CO[R2])O[R3]. MG(15:0/0:0/0:0) is made up of one pentadecanoyl(R1).
MG(i-15:0/0:0/0:0)
MG(i-15:0/0:0/0:0) belongs to the family of monoradyglycerols, which are glycerolipids lipids containing a common glycerol backbone to which at one fatty acyl group is attached. Their general formula is [R1]OCC(CO[R2])O[R3]. MG(i-15:0/0:0/0:0) is made up of one 13-methyltetradecanoyl(R1).
(3beta,5alpha)-3-Hydroxypregn-16-en-20-one
(3beta,5alpha)-3-Hydroxypregn-16-en-20-one is found in garden tomato. (3beta,5alpha)-3-Hydroxypregn-16-en-20-one is isolated from Lycopersicon esculentum (tomato Isolated from Lycopersicon esculentum (tomato). (3beta,5alpha)-3-Hydroxypregn-16-en-20-one is found in garden tomato. D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones
1,2,4-Nonadecanetriol
1,2,4-Nonadecanetriol is found in fruits. 1,2,4-Nonadecanetriol is a constituent of the unripe fruit of Persea americana (avocado). Cytotoxic agent Constituent of the unripe fruit of Persea americana (avocado). Cytotoxic agent. 1,2,4-Nonadecanetriol is found in fruits.
Ethyltestosterone
Ethyltestosterone is a steroid metabolite; it can be the result of the administration of synthetic steroids used in the past in different anabolic therapies, such as in tuberculosis (i.e.: Dianabon in 1946), or in gynecology (1960s). These abandoned or never commercialized anabolic steroids have been taken up by producers of designer steroids and re-introduced as aids in sports, sometimes with modifications to their structure to avoid being detected in regular screening for doping. These anabolic steroids constitute a threat to the spirit of integrity and fairness in sport and to the health of athletes, since their side effects are unknown. The use of anabolic steroids was banned by the International Olympic Committee for the first time at the Olympic Games in Montreal in 1976. Ethyltestosterone is a common standard used in the screening for human steroids in human urine in sport doping control. (PMID: 15934041, 15712346) [HMDB] Ethyltestosterone is a steroid metabolite; it can be the result of the administration of synthetic steroids used in the past in different anabolic therapies, such as in tuberculosis (i.e.: Dianabon in 1946), or in gynecology (1960s). These abandoned or never commercialized anabolic steroids have been taken up by producers of designer steroids and re-introduced as aids in sports, sometimes with modifications to their structure to avoid being detected in regular screening for doping. These anabolic steroids constitute a threat to the spirit of integrity and fairness in sport and to the health of athletes, since their side effects are unknown. The use of anabolic steroids was banned by the International Olympic Committee for the first time at the Olympic Games in Montreal in 1976. Ethyltestosterone is a common standard used in the screening for human steroids in human urine in sport doping control. (PMID: 15934041, 15712346).
MG(0:0/15:0/0:0)
MG(0:0/15:0/0:0) is a monoacylglyceride. A monoglyceride, more correctly known as a monoacylglycerol, is a glyceride consisting of one fatty acid chain covalently bonded to a glycerol molecule through an ester linkage. Monoacylglycerol can be broadly divided into two groups; 1-monoacylglycerols (or 3-monoacylglycerols) and 2-monoacylglycerols, depending on the position of the ester bond on the glycerol moiety. Normally the 1-/3-isomers are not distinguished from each other and are termed alpha-monoacylglycerols, while the 2-isomers are beta-monoacylglycerols. Monoacylglycerols are formed biochemically via release of a fatty acid from diacylglycerol by diacylglycerol lipase or hormone sensitive lipase. Monoacylglycerols are broken down by monoacylglycerol lipase. They tend to be minor components only of most plant and animal tissues, and indeed would not be expected to accumulate because their strong detergent properties would have a disruptive effect on membranes. 2-Monoacylglycerols are a major end product of the intestinal digestion of dietary fats in animals via the enzyme pancreatic lipase. They are taken up directly by the intestinal cells and converted to triacylglycerols via the monoacylglycerol pathway before being transported in lymph to the liver. Mono- and Diglycerides are commonly added to commercial food products in small quantities. They act as emulsifiers, helping to mix ingredients such as oil and water that would not otherwise blend well. MG(0:0/15:0/0:0) belongs to the family of monoradyglycerols, which are glycerolipids lipids containing a common glycerol backbone to which at one fatty acyl group is attached. Their general formula is [R1]OCC(CO[R2])O[R3]. MG(0:0/15:0/0:0) is made up of one pentadecanoyl(R2).
(+)-15,16-Dihydroxyoctadecanoic acid
Prepared from Camelina sativa (false flax). (+)-15,16-Dihydroxyoctadecanoic acid is found in fats and oils. (+)-15,16-Dihydroxyoctadecanoic acid is found in fats and oils. Prepared from Camelina sativa (false flax
1-Phenyl-1,3-pentadecanedione
1-Phenyl-1,3-pentadecanedione is found in fats and oils. 1-Phenyl-1,3-pentadecanedione is a constituent of the pollen of Helianthus annuus (sunflower) Constituent of the pollen of Helianthus annuus (sunflower). 1-Phenyl-1,3-pentadecanedione is found in fats and oils.
5-alpha-Pregnan-3,20-dione
5-alpha-pregnan-3,20-dione is part of the Protein modification, Steroid hormone biosynthesis, and Prostate cancer pathways. It is a substrate for: Probable polyprenol reductase, 3-oxo-5-alpha-steroid 4-dehydrogenase 1, and 3-oxo-5-alpha-steroid 4-dehydrogenase 2.
MG(0:0/i-15:0/0:0)
MG(0:0/i-15:0/0:0) belongs to the family of monoradyglycerols, which are glycerolipids lipids containing a common glycerol backbone to which at one fatty acyl group is attached. Their general formula is [R1]OCC(CO[R2])O[R3]. MG(0:0/i-15:0/0:0) is made up of one 13-methyltetradecanoyl(R2).
MG(0:0/a-15:0/0:0)[rac]
MG(0:0/a-15:0/0:0) belongs to the family of monoradyglycerols, which are glycerolipids lipids containing a common glycerol backbone to which at one fatty acyl group is attached. Their general formula is [R1]OCC(CO[R2])O[R3]. MG(0:0/a-15:0/0:0) is made up of one 12-methyltetradecanoyl(R2).
MG(a-15:0/0:0/0:0)[rac]
MG(a-15:0/0:0/0:0) belongs to the family of monoradyglycerols, which are glycerolipids lipids containing a common glycerol backbone to which at one fatty acyl group is attached. Their general formula is [R1]OCC(CO[R2])O[R3]. MG(a-15:0/0:0/0:0) is made up of one 12-methyltetradecanoyl(R1).
1,3-Benzenediol, 2-(3,7-dimethyl-2,6-octadienyl)-5-pentyl-, (E)-
3-Hydroxypregn-5-en-20-one
20-Hydroxypregn-4-en-3-one
3-Hydroxypregn-4-en-20-one
5beta-Pregnane-3,20-dione
hydroxypregn-4-en-3-one
Dihydroxystearic acid
Dihydroxystearic acid, also known as dihydroxystearate, is a member of the class of compounds known as long-chain fatty acids. Long-chain fatty acids are fatty acids with an aliphatic tail that contains between 13 and 21 carbon atoms. Dihydroxystearic acid is practically insoluble (in water) and a weakly acidic compound (based on its pKa). Dihydroxystearic acid can be found in peanut, which makes dihydroxystearic acid a potential biomarker for the consumption of this food product.
(3E,5E,10E)-7-Ethoxy-3,7,11,15-tetramethylhexadeca-1,3,5,10,14-pentaene
(3Z,5E,10E)-7-Ethoxy-3,7,11,15-tetramethylhexadeca-1,3,5,10,14-pentaene
5-[(2Z,8Z)-2,8-Pentadecadien-1-yl]-1,3-benzenediol
2,4-bis(3-methylbut-2-enyl)-5-pentylbenzene-1,3-diol
niphatesine H|O-methyl-N-(14-(pyridin-3-yl)tetradec-11-ynyl)hydroxylamine
13-Isopropyliden-podocarp-7-en-15-saeure-methylester
(+)-Methyl cembra-1,3,7,11-tetraene-16-carboxylate
11-Hydroxy-12-methoxyabieta-8,11,13-trien|11-hydroxy-12-methoxyabieta-8,11,13-triene|12-methoxyabieta-8,11,13-trien-11-ol
(3Z,9Z,12Z)-6,7:15,16-bisepoxyhenicosa-3,9,12,20-tetraene
3beta-Hydroxy-20-oxo-5alpha-pregnen-14|3beta-Hydroxy-5alpha,17beta-pregn-14-en-20-one|3beta-Hydroxy-5alpha-Delta14-pregnenon-(20)|3beta-Hydroxy-5alpha-pregn-14-en-20-on|3beta-hydroxy-5alpha-pregn-14-en-20-one
(-)-methyl trachyloban-19-oate|methyl trachyloban-19-oate|Methyl-trachyloban-19-oat|Trachylobanin-saeure-methylester
Podocarpa-8(14),12-dien-15-oic acid, 13-isopropyl-, methyl ester
(3beta)-15-methoxyabieta-8,11,13-trien-3-ol|isolophanthin B
methyl 10(9?11)abeo-ent-halima-5(10),9(11),13E-triene-15-oate|scopariusin A
(1R,2E,4S,6E,10E,14S)-4-hydroxy-3,7,11,15,15-pentamethylbicyclo[12.1.0]pentadeca-2,6,10-trien-5-one|(2E,5betab,6E,12E)-5-Hydroxycasba-2,6,12-trien-4-one
12-deoxy-11,12-dihydro-seco-hinokiol methyl ester|methyl 3-[(1S,2S)-6-isopropyl-1-methyl-2-(prop-1-en-2-yl)-1,2,3,4,7,8-hexahydronaphthalen-1-yl]propanoate
15,16-dihydroxy-ent-labda-7,13-diene-15-oic acid lactone
Podocarp-8-en-15-oic acid, 13.beta.-methyl-13-vinyl-, methyl ester
Me ester-Abeoanticopalic acid|methyl abeoanticopalate
(3Z,9Z,15Z)-6,7:12,13-bisepoxyhenicosa-3,9,15,20-tetraene|9,10:15,16-Diepoxide-(all-Z)-1,6,9,12,15,18-Heneicosahexaene
FA 21:5
Cis-5,8,11,14,17-eicosapentaenoic acid methyl ester is a fatty acid methyl ester. cis-5,8,11,14,17-Eicosapentaenoic acid methyl ester is a natural product found in Murrayella periclados and Marchantia polymorpha with data available. Eicosapentaenoic acid methyl ester is a degradant of a monogalactosyl diacylglycerol (an anticancer compound by inducing apoptosis)[1]. Eicosapentaenoic acid methyl ester is a degradant of a monogalactosyl diacylglycerol (an anticancer compound by inducing apoptosis)[1].
Pregnenolone
A 20-oxo steroid that is pregn-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 20. C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C1636 - Therapeutic Steroid Hormone D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones COVID info from COVID-19 Disease Map Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS Pregnenolone is a derivative of cholesterol, the product of Cytochrome P450 side-chain cleavage (EC 1.14.15.6, CYP11A1); this reaction consists of three consecutive monooxygenations; a 22-hydroxylation, 20-hydroxylation and the cleavage of the C20-C22 bond, yielding pregnenolone. Pregnenolone is the precursor to gonadal steroid hormones and the adrenal corticosteroids. This reaction occurs in steroid hormone-producing tissues such as the adrenal cortex, corpus luteum and placenta. The most notable difference between the placenta and other steroidogenic tissues is that electron supply to CYP11A1 limits the rate at which cholesterol is converted to pregnenolone in the placenta. The limiting component for electron delivery to CYP11A1 is the concentration of adrenodoxin reductase in the mitochondrial matrix which is insufficient to maintain the adrenodoxin pool in a fully reduced state. Pregnenolone is also a neurosteroid, and is produced in the spinal cord; CYP11A1 is the key enzyme catalyzing the conversion of cholesterol into pregnenolone, the rate-limiting step in the biosynthesis of all classes of steroids, and has been localized in sensory networks of the spinal cord dorsal horn. In the adrenal glomerulosa cell angiotensin II, one of the major physiological regulators of mineralocorticoid synthesis, appears to affect most of the cholesterol transfer to the mitochondrial outer membrane and transport to the inner membrane steps and thus to exerts a powerful control over the use of cholesterol for aldosterone production. (PMID: 17222962, 15823613, 16632873, 15134809) [HMDB]. Pregnenolone is found in many foods, some of which are common wheat, yellow bell pepper, oval-leaf huckleberry, and fenugreek. Pregnenolone (3β-Hydroxy-5-pregnen-20-one) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone can protect the brain from cannabis intoxication[1][2]. Pregnenolone is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels[3]. Pregnenolone (3β-Hydroxy-5-pregnen-20-one) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone can protect the brain from cannabis intoxication[1][2]. Pregnenolone is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels[3].
2,3-dihydroxypropyl 13-methyltetradecanoate
methyl (1S,5R,9S,13R)-5,9-dimethyl-14-methylidenetetracyclo[11.2.1.0¹,¹⁰.0⁴,⁹]hexadecane-5-carboxylate
16-Pregnolone
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones
Kaurenoic Acid Methyl Ester
5-alpha-Pregnan-3,20-dione
Eicosapentaenoic acid methyl ester
Eicosapentaenoic acid methyl ester is a degradant of a monogalactosyl diacylglycerol (an anticancer compound by inducing apoptosis)[1]. Eicosapentaenoic acid methyl ester is a degradant of a monogalactosyl diacylglycerol (an anticancer compound by inducing apoptosis)[1].
FA 18:0;O2
The (9S,10S)-9,10-dihydroxy derivative of stearic acid.
Calusterone
C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C1636 - Therapeutic Steroid Hormone C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C2360 - Anabolic Steroid
ST 21:2;O2
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones > D011372 - Progestins 5a-Pregnane-3,20-dione is the endogenous progesterone metabolite.
4,4,5,5-tetramethyl-2-(4-octylphenyl)-1,3,2-dioxaborolane
TRANS-4-BUTYL-4-(4-FLUOROPHENYL)-1,1-BI(CYCLOHEXANE)
1-(TRANS-4-(2-(TRANS-4-ETHYLCYCLOHEXYL)ETHYL)CYCLOHEXYL)-4-FLUOROBENZENE
trans-4-Pentylcyclohexanecarboxylic acid 4-propylphenyl ester
METHYL ABIETATE
4-Pregnene-3beta-ol-20-one
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones
4-Pentylphenyl trans-4-propylcyclohexanecarboxylate
(5alpha,17beta)-17-Methylspiro[androstane-3,3-[3H]diazirin]-17-ol
(5beta,17beta)-17-Methyl-spiro[androstane-3,3-[3H]diazirin]-17-ol
3-[(8Z,11Z)-Pentadeca-8,11-dien-1-YL]benzene-1,2-diol
1-[(3S,10R,13S,17S)-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]ethanone
3-Ethynylandrostane-3,17-diol, (3beta,5alpha,17beta)-
Bolasterone
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones > D045930 - Anabolic Agents C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C2360 - Anabolic Steroid Same as: D03144
CMC_13393
C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C1636 - Therapeutic Steroid Hormone D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones COVID info from COVID-19 Disease Map Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS Pregnenolone (3β-Hydroxy-5-pregnen-20-one) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone can protect the brain from cannabis intoxication[1][2]. Pregnenolone is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels[3]. Pregnenolone (3β-Hydroxy-5-pregnen-20-one) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone can protect the brain from cannabis intoxication[1][2]. Pregnenolone is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels[3].
E2012_SIGMA
Eicosapentaenoic acid methyl ester is a degradant of a monogalactosyl diacylglycerol (an anticancer compound by inducing apoptosis)[1]. Eicosapentaenoic acid methyl ester is a degradant of a monogalactosyl diacylglycerol (an anticancer compound by inducing apoptosis)[1].
5beta-Pregnane-3,20-dione
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones
(9S,10R)-dihydroxyoctadecanoic acid
A hydroxy fatty acid that is octadecanoic acid carrying two hydroxy substituents at positions 9 and 10.
MG(15:0/0:0/0:0)
MG(15:0/0:0/0:0) is a monoacylglyceride. A monoglyceride, more correctly known as a monoacylglycerol, is a glyceride consisting of one fatty acid chain covalently bonded to a glycerol molecule through an ester linkage. Monoacylglycerol can be broadly divided into two groups; 1-monoacylglycerols (or 3-monoacylglycerols) and 2-monoacylglycerols, depending on the position of the ester bond on the glycerol moiety. Normally the 1-/3-isomers are not distinguished from each other and are termed alpha-monoacylglycerols, while the 2-isomers are beta-monoacylglycerols. Monoacylglycerols are formed biochemically via release of a fatty acid from diacylglycerol by diacylglycerol lipase or hormone sensitive lipase. Monoacylglycerols are broken down by monoacylglycerol lipase. They tend to be minor components only of most plant and animal tissues, and indeed would not be expected to accumulate because their strong detergent properties would have a disruptive effect on membranes. 2-Monoacylglycerols are a major end product of the intestinal digestion of dietary fats in animals via the enzyme pancreatic lipase. They are taken up directly by the intestinal cells and converted to triacylglycerols via the monoacylglycerol pathway before being transported in lymph to the liver. Mono- and Diglycerides are commonly added to commercial food products in small quantities. They act as emulsifiers, helping to mix ingredients such as oil and water that would not otherwise blend well. MG(15:0/0:0/0:0) belongs to the family of monoradyglycerols, which are glycerolipids lipids containing a common glycerol backbone to which at one fatty acyl group is attached. Their general formula is [R1]OCC(CO[R2])O[R3]. MG(15:0/0:0/0:0) is made up of one pentadecanoyl(R1).
[3-Carboxy-2-(6-methylnonanoyloxy)propyl]-trimethylazanium
[3-Carboxy-2-(5-methylnonanoyloxy)propyl]-trimethylazanium
[3-Carboxy-2-(8-methylnonanoyloxy)propyl]-trimethylazanium
[3-Carboxy-2-(7-methylnonanoyloxy)propyl]-trimethylazanium
[3-Carboxy-2-(4-methylnonanoyloxy)propyl]-trimethylazanium
[3-Carboxy-2-(3-methylnonanoyloxy)propyl]-trimethylazanium
3,18-Dihydroxystearic acid
A dihydroxy monocarboxylic acid that consists of stearic (octadecanoic) acid bearing two hydroxy substituents at positions 3 and 18.
2-(Hexylamino)-1-[4-(phenylmethyl)-1-piperidinyl]ethanone
12,18-Dihydroxyoctadecanoic acid
A long-chain fatty acid that is octadecanoic (stearic) acid substituted at positions 12 and 18 by hydroxy groups.
Methyl 8-(pentacyclo[6.4.0.0(2,7).0(3,6).0(9,12)]dodec-4-yl)octanoate
(3R)-3,18-dihydroxystearic acid
A dihydroxy monocarboxylic acid that is 18-hydroxystearic acid (18-hydroxyoctadecanoic acid) in which the pro-R hydrogen beta to the carboxy group is replaced by a hydroxy group.
(3R,17R)-3,17-dihydroxystearic acid
An (omega-1)-hydroxy fatty acid that is (17R)-17-hydroxystearic acid ((17R)-17-hydroxyoctadecanoic acid) in which the 3-pro-R hydrogen is replaced by a hydroxy group.
1-[(3S,8R,9R,10R,13S,14S,17S)-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]ethanone
(5R,8R,9S,10S,13S,14S)-17-acetyl-10,13-dimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-one
[(2R)-3-carboxy-2-decanoyloxypropyl]-dimethyl-(trideuteriomethyl)azanium
(4R)-4,11bbeta-Dimethyl-8-methylene-tetradecahydro-6abeta,9beta-methano-6aH-cyclohepta[a]naphthalene-4beta-carboxylic acid methyl ester
(9E,11E,13E,15E,17E)-henicosa-9,11,13,15,17-pentaenoic acid
1-[(3R,5S,10S,13S)-3-hydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]ethanone
1-[(3S,8S,9R,10R,13S,14S,17R)-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]ethanone
DHSA
9,10-dihydroxyoctadecanoic acid is a hydroxy-fatty acid formally derived from octacecanoic (stearic) acid by hydroxy substitution at positions 9 and 10. It is a dihydroxy monocarboxylic acid and a hydroxyoctadecanoic acid. It is a conjugate acid of a 9,10-dihydroxystearate. 9,10-Dihydroxystearic acid is a natural product found in Trypanosoma brucei and Apis cerana with data available. A hydroxy-fatty acid formally derived from stearic acid by hydroxy substitution at positions 9 and 10.
5α-Dihydroprogesterone
A C21-steroid hormone that is 5alpha-pregnane substituted by oxo groups at positions 3 and 20. It is a metabolite of progestrone. D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones 5a-Pregnane-3,20-dione is the endogenous progesterone metabolite.
(20R)-20-hydroxypregn-4-en-3-one
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones > D011372 - Progestins
5beta-pregnane-3,20-dione
A C21-steroid that is 5beta-pregnane with oxo groups at positions 3 and 20.
(9R,10S)-dihydroxyoctadecanoic acid
A dihydroxy monocarboxylic acid that is octadecanoic acid in which the two hydroxy groups are located at positions 9R and 10S.
20-hydroxypregn-4-en-3-one
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones
17beta-Hydroxy-2,17-dimethyl-5alpha-androst-1-en-3-one
JNJ-5207852
JNJ-5207852 is a selective and potent histamine H3 receptor (H3R) antagonist, with pKis of 8.9, 9.24 for rat and human H3R, respectively.
Heneicosapentaenoate (21:5n3)
Heneicosapentaenoic Acid (HPEA) is a polyunsaturated omega-3 fatty acid. Its chemical structure features a 21-carbon long chain with five double bonds located at the 9th, 12th, 15th, 18th, and 21st carbon atoms. This arrangement of double bonds makes it an important component in various biological processes, such as inflammation regulation and cell signaling. However, it’s important to note that HPEA is not as well-known or extensively studied as other omega-3 fatty acids like EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid).
(3z,5e,7s,10e)-7-ethoxy-3,7,11,15-tetramethylhexadeca-1,3,5,10,14-pentaene
(2s,4as,10ar)-7-(2-methoxypropan-2-yl)-1,1,4a-trimethyl-2,3,4,9,10,10a-hexahydrophenanthren-2-ol
1-{7-hydroxy-9a,11a-dimethyl-1h,2h,3h,3ah,4h,5h,5ah,6h,7h,8h,9h,10h,11h-cyclopenta[a]phenanthren-1-yl}ethanone
methyl (1s,2r,6r,7s,10s,12r,13r,14s)-2,6,12-trimethylpentacyclo[11.2.1.0¹,¹⁰.0²,⁷.0¹²,¹⁴]hexadecane-6-carboxylate
(1s,3as,3br,5ar,9as,9bs,11as)-1-acetyl-9a,11a-dimethyl-tetradecahydrocyclopenta[a]phenanthren-2-one
methyl 2-(4,8,12-trimethylcyclotetradeca-1,3,7,11-tetraen-1-yl)propanoate
1-[(3ar,3bs,5as,7s,9as,9br,11as)-7-hydroxy-9a,11a-dimethyl-3h,3ah,3bh,4h,5h,5ah,6h,7h,8h,9h,9bh,10h,11h-cyclopenta[a]phenanthren-1-yl]ethanone
methyl (1s,4as,4bs,10as)-7-isopropyl-1,4a-dimethyl-2,3,4,4b,5,6,10,10a-octahydrophenanthrene-1-carboxylate
1-[(3as,3br,5as,7s,9as,9bs,11as)-7-hydroxy-9a,11a-dimethyl-3h,3ah,3bh,4h,5h,5ah,6h,7h,8h,9h,9bh,10h,11h-cyclopenta[a]phenanthren-1-yl]ethanone
2-isopropyl-3-methoxy-4b,8,8-trimethyl-5,6,7,8a,9,10-hexahydrophenanthren-4-ol
8-isopropyl-7-methoxy-1,1,4a-trimethyl-2,3,4,9,10,10a-hexahydrophenanthren-9-ol
3-(hexadeca-8,11-dien-1-yl)-5-methylidenefuran-2-one
(2r)-2-methyl-2-(4-methylpent-3-en-1-yl)-7-pentyl-3,4-dihydro-1-benzopyran-5-ol
1-[(1s,3ar,5as,7s,9as,11as)-7-hydroxy-9a,11a-dimethyl-1h,2h,3h,3ah,4h,5h,5ah,6h,7h,8h,9h,10h,11h-cyclopenta[a]phenanthren-1-yl]ethanone
methyl 7-ethenyl-1,4a,7-trimethyl-3,4,6,8,8a,9,10,10a-octahydro-2h-phenanthrene-1-carboxylate
methyl 5-{3a,7b-dimethyl-5-methylidene-octahydrocyclopropa[a]naphthalen-4-yl}-3-methylpent-2-enoate
methyl (1s,4ar,5s,8ar)-1,4a-dimethyl-6-methylidene-5-[(2e)-3-methylpenta-2,4-dien-1-yl]-hexahydro-2h-naphthalene-1-carboxylate
12-o-methylpisiferanol
{"Ingredient_id": "HBIN000949","Ingredient_name": "12-o-methylpisiferanol","Alias": "NA","Ingredient_formula": "C21H32O2","Ingredient_Smile": "CC(C)C1=C(C=C2CC3(CCCC(C3CCC2=C1)(C)C)O)OC","Ingredient_weight": "NA","OB_score": "NA","CAS_id": "NA","SymMap_id": "NA","TCMID_id": "14671","TCMSP_id": "NA","TCM_ID_id": "NA","PubChem_id": "NA","DrugBank_id": "NA"}
1-(3,4-methylenedioxyphenyl)-1e-tetradecene
{"Ingredient_id": "HBIN001032","Ingredient_name": "1-(3,4-methylenedioxyphenyl)-1e-tetradecene","Alias": "NA","Ingredient_formula": "C21H32O2","Ingredient_Smile": "CCCCCCCCCCCCC=CC1=CC2=C(C=C1)OCO2","Ingredient_weight": "NA","OB_score": "NA","CAS_id": "NA","SymMap_id": "NA","TCMID_id": "14375","TCMSP_id": "NA","TCM_ID_id": "NA","PubChem_id": "NA","DrugBank_id": "NA"}
