Exact Mass: 316.232
Exact Mass Matches: 316.232
Found 500 metabolites which its exact mass value is equals to given mass value 316.232,
within given mass tolerance error 0.05 dalton. Try search metabolite list with more accurate mass tolerance error
0.01 dalton.
Pregnenolone
Pregnenolone is a derivative of cholesterol, the product of cytochrome P450 side-chain cleavage (EC 1.14.15.6, CYP11A1. This reaction consists of three consecutive monooxygenations, a 22-hydroxylation, a 20-hydroxylation, and the cleavage of the C20-C22 bond, yielding pregnenolone. Pregnenolone is the precursor to gonadal steroid hormones and the adrenal corticosteroids. This reaction occurs in steroid hormone-producing tissues such as the adrenal cortex, corpus luteum, and placenta. The most notable difference between the placenta and other steroidogenic tissues is that electron supply to CYP11A1 limits the rate at which cholesterol is converted into pregnenolone in the placenta. The limiting component for electron delivery to CYP11A1 is the concentration of adrenodoxin reductase in the mitochondrial matrix which is insufficient to maintain the adrenodoxin pool in a fully reduced state. Pregnenolone is also a neurosteroid, and is produced in the spinal cord; CYP11A1 is the key enzyme catalyzing the conversion of cholesterol into pregnenolone, the rate-limiting step in the biosynthesis of all classes of steroids, and has been localized in sensory networks of the spinal cord dorsal horn. In the adrenal glomerulosa cell, angiotensin II, one of the major physiological regulators of mineralocorticoid synthesis, appears to affect most of the cholesterol transfer to the mitochondrial outer membrane and many steps in the transport to the inner membrane. Thus, it exerts a powerful control over the use of cholesterol for aldosterone production (PMID: 17222962, 15823613, 16632873, 15134809). C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C1636 - Therapeutic Steroid Hormone D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones COVID info from COVID-19 Disease Map Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS Pregnenolone (3β-Hydroxy-5-pregnen-20-one) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone can protect the brain from cannabis intoxication[1][2]. Pregnenolone is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels[3]. Pregnenolone (3β-Hydroxy-5-pregnen-20-one) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone can protect the brain from cannabis intoxication[1][2]. Pregnenolone is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels[3].
cannabigerol
A member of the class of resorcinols that is resorcinol which is substituted by a (2E)-3,7-dimethylocta-2,6-dien-1-yl group at position 2 and by a pentyl group at position 5. It is a natural product found in Cannabis sativa and Helichrysum species.
20alpha-Dihydroprogesterone
20alpha-Dihydroprogesterone is a biologically active 20-alpha-reduced metabolite of progesterone. It is converted from progesterone to 20-alpha-hydroxypregn-4-en-3-one by the 20-alpha-hydroxysteroid dehydrogenase in the corpus luteum and the placenta. Progesterone is a C-21 steroid hormone involved in the female menstrual cycle, pregnancy (supports gestation), and embryogenesis of humans and other species. Progesterone belongs to a class of hormones called progestagens, and is the major naturally occurring human progestagen (Wikipedia). During implantation and gestation, progesterone appears to decrease the maternal immune response to allow for the acceptance of the pregnancy. Progesterone decreases contractility of the uterine smooth muscle. The fetus metabolizes placental progesterone in the production of adrenal mineralo- and glucosteroids. A drop in progesterone levels is possibly one step that facilitates the onset of labour. In addition, progesterone inhibits lactation during pregnancy. The fall in progesterone levels following delivery is one of the triggers for milk production (Wikipedia). A biologically active 20-alpha-reduced metabolite of progesterone. It is converted from progesterone to 20-alpha-hydroxypregn-4-en-3-one by the 20-alpha-hydroxysteroid dehydrogenase in the corpus luteum and the placenta. -- Pubchem; Progesterone is a C-21 steroid hormone involved in the female menstrual cycle, pregnancy (supports gestation) and embryogenesis of humans and other species. Progesterone belongs to a class of hormones called progestagens, and is the major naturally occurring human progestagen. -- Wikipedia; During implantation and gestation, progesterone appears to decrease the maternal immune response to allow for the acceptance of the pregnancy. Progesterone decreases contractility of the uterine smooth muscle. The fetus metabolizes placental progesterone in the production of adrenal mineralo- and glucosteroids. A drop in progesterone levels is possibly one step that facilitates the onset of labor. In addition progesterone inhibits lactation during pregnancy. The fall in progesterone levels following delivery is one of the triggers for milk production. -- Wikipedia [HMDB] D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones > D011372 - Progestins
5a-Pregnane-3,20-dione
5a-Pregnane-3,20-dione is a biologically active 5-alpha-reduced metabolite of plasma progesterone. It is the immediate precursor of 5-alpha-pregnan-3-alpha-ol-20-one (allopregnanolone), a neuroactive steroid that binds with GABA(A) receptor. A biologically active 5-alpha-reduced metabolite of plasma progesterone. It is the immediate precursor of 5-alpha-pregnan-3-alpha-ol-20-one (allopregnanolone), a neuroactive steroid that binds with GABA(A) receptor. [HMDB] D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones 5a-Pregnane-3,20-dione is the endogenous progesterone metabolite.
Bolasterone
Bolasterone is an anabolic androgenic steroid. Analysis of steroids in urine has been used to detect different hormonal actions in human beings such as testicular function in men, hyperandrogenic disorders in women and puberty problems in children, by the measurement of anabolic steroids, and some hormonal disorders such as adrenocortical adenoma and Cushing syndrome by the control of corticoids. This steroid have been included in the International Olympic Committee (IOC) doping list due to their illegal use in some sports and in the list of schedules drugs in several countries because of its use by young people. In addition, the examination of endogenous steroids profile provides information about the health and the use of exogenous steroids. Bolasterone is excreted as the original compound in human urine. Androgenic anabolic steroids (AAS) are defined as natural, synthetic or semi-synthetic drugs chemicals derived from testosterone, used with the aim to improve physical performance by increasing both muscle strength and mass. Despite their reported toxicological effects on the cardiovascular, hepatic and neuro-endocrine systems, the AAS have been extensively used in sports activities. The use of anabolic steroids was banned by the International Olympic Committee for the first time at the Olympic Games in Montreal in 1976. Since that time the misuse of anabolic steroids by athletes has been controlled by analysis of urine of the excreted steroids or their metabolites, or both. (PMID: 10892583, 10932808, 14976846, 15042372, 15231229, 3308301, 8456050, 8674183, 16040239) [HMDB] Bolasterone is an anabolic androgenic steroid. Analysis of steroids in urine has been used to detect different hormonal actions in human beings such as testicular function in men, hyperandrogenic disorders in women and puberty problems in children, by the measurement of anabolic steroids, and some hormonal disorders such as adrenocortical adenoma and Cushing syndrome by the control of corticoids. This steroid have been included in the International Olympic Committee (IOC) doping list due to their illegal use in some sports and in the list of schedules drugs in several countries because of its use by young people. In addition, the examination of endogenous steroids profile provides information about the health and the use of exogenous steroids. Bolasterone is excreted as the original compound in human urine. Androgenic anabolic steroids (AAS) are defined as natural, synthetic or semi-synthetic drugs chemicals derived from testosterone, used with the aim to improve physical performance by increasing both muscle strength and mass. Despite their reported toxicological effects on the cardiovascular, hepatic and neuro-endocrine systems, the AAS have been extensively used in sports activities. The use of anabolic steroids was banned by the International Olympic Committee for the first time at the Olympic Games in Montreal in 1976. Since that time the misuse of anabolic steroids by athletes has been controlled by analysis of urine of the excreted steroids or their metabolites, or both. (PMID: 10892583, 10932808, 14976846, 15042372, 15231229, 3308301, 8456050, 8674183, 16040239). D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones > D045930 - Anabolic Agents C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C2360 - Anabolic Steroid Same as: D03144
6alpha,17alpha-Dimethyltestosterone
2alpha,17-Dimethyltestosterone
Norbolethone
Norbolethone is a 19-nor anabolic steroid first synthesized in 1966. During the 1960s it was administered to humans in efficacy studies concerned with short stature and underweight conditions. It has never been reported by doping control laboratories prior to 2001. Norbolethone was identified in two urine samples from one athlete by matching the mass spectra and chromatographic retention times with those of a reference standard. The samples also contained at least one likely metabolite. The samples were also unusual because the concentrations of endogenous steroids were exceptionally low. Since norbolethone is not known to be marketed by any pharmaceutical company, a clandestine source of norbolethone may exist. Norbolethone matches the description for what is described as a "designer steroid." Androgenic anabolic steroids (AAS) are defined as natural, synthetic or semi-synthetic drugs chemicals derived from testosterone, used with the aim to improve physical performance by increasing both muscle strength and mass. Despite their reported toxicological effects on the cardiovascular, hepatic and neuro-endocrine systems, the AAS have been extensively used in sports activities. (PMID: 12112254) [HMDB] Norbolethone is a 19-nor anabolic steroid first synthesized in 1966. During the 1960s it was administered to humans in efficacy studies concerned with short stature and underweight conditions. It has never been reported by doping control laboratories prior to 2001. Norbolethone was identified in two urine samples from one athlete by matching the mass spectra and chromatographic retention times with those of a reference standard. The samples also contained at least one likely metabolite. The samples were also unusual because the concentrations of endogenous steroids were exceptionally low. Since norbolethone is not known to be marketed by any pharmaceutical company, a clandestine source of norbolethone may exist. Norbolethone matches the description for what is described as a "designer steroid." Androgenic anabolic steroids (AAS) are defined as natural, synthetic or semi-synthetic drugs chemicals derived from testosterone, used with the aim to improve physical performance by increasing both muscle strength and mass. Despite their reported toxicological effects on the cardiovascular, hepatic and neuro-endocrine systems, the AAS have been extensively used in sports activities. (PMID: 12112254). C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C2360 - Anabolic Steroid
5-beta-pregnan-3,20 dione
(5beta)-pregnane-3,20-dione, also known as 3,20-pregnanedione or 5beta-dihydroprogesterone, belongs to gluco/mineralocorticoids, progestogins and derivatives class of compounds. Those are steroids with a structure based on a hydroxylated prostane moiety. Thus, (5beta)-pregnane-3,20-dione is considered to be a steroid lipid molecule (5beta)-pregnane-3,20-dione is practically insoluble (in water) and an extremely weak acidic compound (based on its pKa). (5beta)-pregnane-3,20-dione can be found in a number of food items such as opium poppy, walnut, rowal, and italian sweet red pepper, which makes (5beta)-pregnane-3,20-dione a potential biomarker for the consumption of these food products.
5-(8,11-Pentadecadienyl)-1,3-benzenediol
5-[(8Z,11Z)-pentadeca-8,11-dien-1-yl]benzene-1,3-diol is a member of resorcinols. 5-[(8Z,11Z)-pentadeca-8,11-dien-1-yl]benzene-1,3-diol is a natural product found in Merulius incarnatus, Anacardium occidentale, and Gloeostereum incarnatum with data available. 5-(8,11-Pentadecadienyl)-1,3-benzenediol is found in nuts. 5-(8,11-Pentadecadienyl)-1,3-benzenediol is isolated from Anacardium occidentale (cashew). Isolated from Anacardium occidentale (cashew). 5-(8,11-Pentadecadienyl)-1,3-benzenediol is found in nuts.
Kaurenoic acid methyl ester
Kaurenoic acid methyl ester is found in fats and oils. Kaurenoic acid methyl ester is isolated from Helianthus annuus (sunflower). Isolated from Helianthus annuus (sunflower). Kaurenoic acid methyl ester is found in fats and oils.
Calusterone
Calusterone is an androgenic steroid. Calusterone induce given orally induce a marked decrease (between 30 and 70\\% depending on the dose) in the binding capacity of oestradiol-17beta to specific uterine receptors in vivo. As an androgen, calusterone has been used as a therapeutic agent in postmenopausal women with metastatic breast cancer; the addition of a potent hormonal agent to effective cytotoxic chemotherapy improves the results of treatment of women with metastatic breast cancer. Calusterone is tested in sport screening; fast and sensitive method for the comprehensive screening of anabolic agents and other banned doping substances using gas chromatography/tandem mass spectrometry (GC/MS/MS) with an external ionization ion trap mass spectrometer have been developed for the parent substances and their metabolites. (PMID: 17610244, 12375280, 153787, 2325376, 12375280) [HMDB] Calusterone is an androgenic steroid. Calusterone induce given orally induce a marked decrease (between 30 and 70\\% depending on the dose) in the binding capacity of oestradiol-17beta to specific uterine receptors in vivo. As an androgen, calusterone has been used as a therapeutic agent in postmenopausal women with metastatic breast cancer; the addition of a potent hormonal agent to effective cytotoxic chemotherapy improves the results of treatment of women with metastatic breast cancer. Calusterone is tested in sport screening; fast and sensitive method for the comprehensive screening of anabolic agents and other banned doping substances using gas chromatography/tandem mass spectrometry (GC/MS/MS) with an external ionization ion trap mass spectrometer have been developed for the parent substances and their metabolites. (PMID: 17610244, 12375280, 153787, 2325376, 12375280). D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones > D045930 - Anabolic Agents C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C1636 - Therapeutic Steroid Hormone C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C2360 - Anabolic Steroid Same as: D03144
Furanojaponin
Constituent of Petasites japonicus (sweet coltsfoot). Furanojaponin is found in giant butterbur and green vegetables. Furanojaponin is found in giant butterbur. Furanojaponin is a constituent of Petasites japonicus (sweet coltsfoot)
(4Z,9a)-9-(3-Methyl-2-butenoyloxy)-4,10(14)-oplopadien-3-one
(4Z,9a)-9-(3-Methyl-2-butenoyloxy)-4,10(14)-oplopadien-3-one is found in tea. (4Z,9a)-9-(3-Methyl-2-butenoyloxy)-4,10(14)-oplopadien-3-one is a constituent of Tussilago farfara (coltsfoot) Constituent of Tussilago farfara (coltsfoot). (4Z,9a)-9-(3-Methyl-2-butenoyloxy)-4,10(14)-oplopadien-3-one is found in tea.
ent-17-Oxo-15-kauren-19-oic acid
ent-17-Oxo-15-kauren-19-oic acid is a constituent of Helianthus species. Constituent of Helianthus subspecies
(3beta,5alpha)-3-Hydroxypregn-16-en-20-one
(3beta,5alpha)-3-Hydroxypregn-16-en-20-one is found in garden tomato. (3beta,5alpha)-3-Hydroxypregn-16-en-20-one is isolated from Lycopersicon esculentum (tomato Isolated from Lycopersicon esculentum (tomato). (3beta,5alpha)-3-Hydroxypregn-16-en-20-one is found in garden tomato. D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones
Yucalexin B9
Yucalexin B9 is found in root vegetables. Yucalexin B9 is a constituent of cassava root Manihot esculenta Constituent of cassava root Manihot esculenta. Yucalexin B9 is found in root vegetables.
Momilactone C
Momilactone C is found in cereals and cereal products. Momilactone C is a constituent of Oryza sativa (rice). Constituent of Oryza sativa (rice). Momilactone C is found in cereals and cereal products and rice.
Phytocassane A
Phytoalexin from Oryza sativa (rice). Phytocassane A is found in cereals and cereal products and rice. Phytocassane A is found in cereals and cereal products. Phytoalexin from Oryza sativa (rice).
6b-Hydroxymethandienone
6b-Hydroxymethandienone is a metabolite of the androgen metandienone metabolite, excreted in the urine. Metandienone has been used in horse doping and by weightlifters and body builders. It is of note to consider that the use of anabolic steroids for an extended period of time reduces the excretion of endogenous metabolites, making the detection of doping a little more difficult. (PMID: 16040239, 757586, 9001954, 2745643, 12375280, 8539789, 1400752, 757586, 17610244) [HMDB] 6b-Hydroxymethandienone is a metabolite of the androgen metandienone metabolite, excreted in the urine. Metandienone has been used in horse doping and by weightlifters and body builders. It is of note to consider that the use of anabolic steroids for an extended period of time reduces the excretion of endogenous metabolites, making the detection of doping a little more difficult. (PMID: 16040239, 757586, 9001954, 2745643, 12375280, 8539789, 1400752, 757586, 17610244).
Trilobinone
Trilobinone is found in herbs and spices. Trilobinone is a constituent of Salvia triloba (Greek sage). Constituent of Salvia triloba (Greek sage). Trilobinone is found in tea and herbs and spices.
2-Methoxyestradiol-3-methylether
Generally refers to the 17-beta-isomer of estradiol, an aromatized C18 steroid with hydroxyl group at 3-beta- and 17-beta-position. estradiol-17-beta is the most potent form of mammalian estrogenic steroids. In humans, it is produced primarily by the cyclic ovaries and the placenta. It is also produced by the adipose tissue of men and postmenopausal women. The 17-alpha-isomer of estradiol binds weakly to estrogen receptors (receptors, estrogen) and exhibits little estrogenic activity in estrogen-responsive tissues. Various isomers can be synthesized.
Ethyltestosterone
Ethyltestosterone is a steroid metabolite; it can be the result of the administration of synthetic steroids used in the past in different anabolic therapies, such as in tuberculosis (i.e.: Dianabon in 1946), or in gynecology (1960s). These abandoned or never commercialized anabolic steroids have been taken up by producers of designer steroids and re-introduced as aids in sports, sometimes with modifications to their structure to avoid being detected in regular screening for doping. These anabolic steroids constitute a threat to the spirit of integrity and fairness in sport and to the health of athletes, since their side effects are unknown. The use of anabolic steroids was banned by the International Olympic Committee for the first time at the Olympic Games in Montreal in 1976. Ethyltestosterone is a common standard used in the screening for human steroids in human urine in sport doping control. (PMID: 15934041, 15712346) [HMDB] Ethyltestosterone is a steroid metabolite; it can be the result of the administration of synthetic steroids used in the past in different anabolic therapies, such as in tuberculosis (i.e.: Dianabon in 1946), or in gynecology (1960s). These abandoned or never commercialized anabolic steroids have been taken up by producers of designer steroids and re-introduced as aids in sports, sometimes with modifications to their structure to avoid being detected in regular screening for doping. These anabolic steroids constitute a threat to the spirit of integrity and fairness in sport and to the health of athletes, since their side effects are unknown. The use of anabolic steroids was banned by the International Olympic Committee for the first time at the Olympic Games in Montreal in 1976. Ethyltestosterone is a common standard used in the screening for human steroids in human urine in sport doping control. (PMID: 15934041, 15712346).
all-trans-18-Hydroxyretinoic acid
all-trans-18-Hydroxyretinoic acid, also known as 18-hydroxyretinoic acid, is classified as a member of the retinoids. Retinoids are oxygenated derivatives of 3,7-dimethyl-1-(2,6,6-trimethylcyclohex-1-enyl)nona-1,3,5,7-tetraene and derivatives thereof. all-trans-18-Hydroxyretinoic acid is considered to be a practically insoluble (in water) and a weakly acidic compound. all-trans-18-Hydroxyretinoic acid is an isoprenoid lipid molecule. Within a cell, all-trans-18-hydroxyretinoic acid is primarily located in the extracellular space and near the membrane. 18-Hydroxyretinoic acid is a metabolite of tretinoin. Tretinoin is the acid form of vitamin A and is also known as all-trans retinoic acid or ATRA. It is a drug commonly used to treat acne vulgaris and keratosis pilaris. It is available as a cream or gel (brand names Aberela, Airol, Renova, Atralin, Retin-A, Avita, Retacnyl, Refissa, or Stieva-A). It is also used to treat acute promyelocytic leukemia (APL) and is sold for this indication by Roche under the brand name Vesanoid. It is also available as a generic. (Wikipedia) A human metabolite taken as a putative food compound of mammalian origin [HMDB]
1-Phenyl-1,3-pentadecanedione
1-Phenyl-1,3-pentadecanedione is found in fats and oils. 1-Phenyl-1,3-pentadecanedione is a constituent of the pollen of Helianthus annuus (sunflower) Constituent of the pollen of Helianthus annuus (sunflower). 1-Phenyl-1,3-pentadecanedione is found in fats and oils.
Rosmaridiphenol
Rosmaridiphenol is found in herbs and spices. Rosmaridiphenol is a constituent of the leaves of Rosmarinus officinalis (rosemary). Constituent of the leaves of Rosmarinus officinalis (rosemary). Rosmaridiphenol is found in herbs and spices and rosemary.
ent-15,16-Epoxy-1(10),13(16),14-halimatrien-19-oic acid
ent-15,16-Epoxy-1(10),13(16),14-halimatrien-19-oic acid is found in fruits. ent-15,16-Epoxy-1(10),13(16),14-halimatrien-19-oic acid is isolated (as Me ester) from seed-pod resin of Hymenaea courbaril (copinol). Isol. (as Me ester) from seed-pod resin of Hymenaea courbaril (copinol). ent-15,16-Epoxy-1(10),13(16),14-halimatrien-19-oic acid is found in fruits.
5-alpha-Pregnan-3,20-dione
5-alpha-pregnan-3,20-dione is part of the Protein modification, Steroid hormone biosynthesis, and Prostate cancer pathways. It is a substrate for: Probable polyprenol reductase, 3-oxo-5-alpha-steroid 4-dehydrogenase 1, and 3-oxo-5-alpha-steroid 4-dehydrogenase 2.
5,6-Epoxy-13-cis-retinoic acid
5,6-Epoxy-13-cis-retinoic acid is an oxygenated metabolite of 13-cis-retinoic acid. It is formed from the hydroperoxide-dependent co-oxidation of 13-cis-retinoic acid by prostaglandin H (PGH) synthase (PMID: 3115987).
5,8-Epoxy-13-cis-retinoic acid
5,8-Epoxy-13-cis-retinoic acid is an oxygenated metabolite of 13-cis-retinoic acid. It is formed from the hydroperoxide-dependent co-oxidation of 13-cis-retinoic acid by prostaglandin H (PGH) synthase (PMID: 3115987).
1,3-Benzenediol, 2-(3,7-dimethyl-2,6-octadienyl)-5-pentyl-, (E)-
3-Hydroxypregn-5-en-20-one
19-Nordeoxycorticosterone
20-Hydroxypregn-4-en-3-one
3-Hydroxypregn-4-en-20-one
5beta-Pregnane-3,20-dione
hydroxypregn-4-en-3-one
5-[(2Z,8Z)-2,8-Pentadecadien-1-yl]-1,3-benzenediol
2,4-bis(3-methylbut-2-enyl)-5-pentylbenzene-1,3-diol
niphatesine H|O-methyl-N-(14-(pyridin-3-yl)tetradec-11-ynyl)hydroxylamine
3alpha-hydroxy-7-oxo-15,16-epoxyfriedolabda-5,13(16),14-trien
ent-3beta-14alpha-Hydroxypimara-7,9(11),15-triene-12-one
(1(9)E,6E,10R)-19-Oxo-1(9),6,13-xenicatrien-18,17-olide|(2R,3R,6E,9E,10R)-17-xenic-6,9,13-trien-1-al-18-oic acid lactone
ent-12beta-hydroxymethyl-3-oxo-16-norpimar-8(14)-ene-15,21-carbolactone
6-Deoxy-(ent-6beta)-6-Hydroxy-7-oxo-3,13-clerodadien-15,16-olide|7-oxo-ent-clerodan-3,13E-dien-15,16-olide
12beta-12-Hysroxy-8,15-isopimaradiene-7,11-dione|12beta-hydroxy-7,11-dioxopimar-8(9),15-dien
13-Isopropyliden-podocarp-7-en-15-saeure-methylester
SCHEMBL9359643
(ent-7??, 12??)-form-7-Hydroxy-8(14), 13(15)-abietadien-16, 12-olide|7beta-hydroxy-ent-abieta-8(14),13(15)-dien-12alpha,16-olide
12-oxoabieta-7,13-dien-18-oic acid|12-oxoabietic acid
(+)-Methyl cembra-1,3,7,11-tetraene-16-carboxylate
11-Hydroxy-12-methoxyabieta-8,11,13-trien|11-hydroxy-12-methoxyabieta-8,11,13-triene|12-methoxyabieta-8,11,13-trien-11-ol
SCHEMBL18799945
(3Z,9Z,12Z)-6,7:15,16-bisepoxyhenicosa-3,9,12,20-tetraene
3beta-Hydroxy-20-oxo-5alpha-pregnen-14|3beta-Hydroxy-5alpha,17beta-pregn-14-en-20-one|3beta-Hydroxy-5alpha-Delta14-pregnenon-(20)|3beta-Hydroxy-5alpha-pregn-14-en-20-on|3beta-hydroxy-5alpha-pregn-14-en-20-one
(-)-methyl trachyloban-19-oate|methyl trachyloban-19-oate|Methyl-trachyloban-19-oat|Trachylobanin-saeure-methylester
Podocarpa-8(14),12-dien-15-oic acid, 13-isopropyl-, methyl ester
(3beta)-15-methoxyabieta-8,11,13-trien-3-ol|isolophanthin B
methyl 10(9?11)abeo-ent-halima-5(10),9(11),13E-triene-15-oate|scopariusin A
(1R,2E,4S,6E,10E,14S)-4-hydroxy-3,7,11,15,15-pentamethylbicyclo[12.1.0]pentadeca-2,6,10-trien-5-one|(2E,5betab,6E,12E)-5-Hydroxycasba-2,6,12-trien-4-one
12-deoxy-11,12-dihydro-seco-hinokiol methyl ester|methyl 3-[(1S,2S)-6-isopropyl-1-methyl-2-(prop-1-en-2-yl)-1,2,3,4,7,8-hexahydronaphthalen-1-yl]propanoate
15,16-dihydroxy-ent-labda-7,13-diene-15-oic acid lactone
Podocarp-8-en-15-oic acid, 13.beta.-methyl-13-vinyl-, methyl ester
9-Hydroxy-heptadecandisaeure|9-hydroxy-heptadecanedioic acid|9-hydroxyheptadecane-1,17-dioic acid
Me ester-Abeoanticopalic acid|methyl abeoanticopalate
(3Z,9Z,15Z)-6,7:12,13-bisepoxyhenicosa-3,9,15,20-tetraene|9,10:15,16-Diepoxide-(all-Z)-1,6,9,12,15,18-Heneicosahexaene
SCHEMBL14510825
Hardwickiicacid
(4aR,5R,6R,8aR)-5-[2-(furan-3-yl)ethyl]-5,6,8a-trimethyl-3,4,4a,6,7,8-hexahydronaphthalene-1-carboxylic acid is a natural product found in Laennecia coulteri, Microglossa pyrifolia, and other organisms with data available.
ent-11α-Hydroxyabieta-8(14),13(15)-dien-16,12α-olide
FA 21:5
Cis-5,8,11,14,17-eicosapentaenoic acid methyl ester is a fatty acid methyl ester. cis-5,8,11,14,17-Eicosapentaenoic acid methyl ester is a natural product found in Murrayella periclados and Marchantia polymorpha with data available. Eicosapentaenoic acid methyl ester is a degradant of a monogalactosyl diacylglycerol (an anticancer compound by inducing apoptosis)[1]. Eicosapentaenoic acid methyl ester is a degradant of a monogalactosyl diacylglycerol (an anticancer compound by inducing apoptosis)[1].
Pregnenolone
A 20-oxo steroid that is pregn-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 20. C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C1636 - Therapeutic Steroid Hormone D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones COVID info from COVID-19 Disease Map Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS Pregnenolone is a derivative of cholesterol, the product of Cytochrome P450 side-chain cleavage (EC 1.14.15.6, CYP11A1); this reaction consists of three consecutive monooxygenations; a 22-hydroxylation, 20-hydroxylation and the cleavage of the C20-C22 bond, yielding pregnenolone. Pregnenolone is the precursor to gonadal steroid hormones and the adrenal corticosteroids. This reaction occurs in steroid hormone-producing tissues such as the adrenal cortex, corpus luteum and placenta. The most notable difference between the placenta and other steroidogenic tissues is that electron supply to CYP11A1 limits the rate at which cholesterol is converted to pregnenolone in the placenta. The limiting component for electron delivery to CYP11A1 is the concentration of adrenodoxin reductase in the mitochondrial matrix which is insufficient to maintain the adrenodoxin pool in a fully reduced state. Pregnenolone is also a neurosteroid, and is produced in the spinal cord; CYP11A1 is the key enzyme catalyzing the conversion of cholesterol into pregnenolone, the rate-limiting step in the biosynthesis of all classes of steroids, and has been localized in sensory networks of the spinal cord dorsal horn. In the adrenal glomerulosa cell angiotensin II, one of the major physiological regulators of mineralocorticoid synthesis, appears to affect most of the cholesterol transfer to the mitochondrial outer membrane and transport to the inner membrane steps and thus to exerts a powerful control over the use of cholesterol for aldosterone production. (PMID: 17222962, 15823613, 16632873, 15134809) [HMDB]. Pregnenolone is found in many foods, some of which are common wheat, yellow bell pepper, oval-leaf huckleberry, and fenugreek. Pregnenolone (3β-Hydroxy-5-pregnen-20-one) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone can protect the brain from cannabis intoxication[1][2]. Pregnenolone is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels[3]. Pregnenolone (3β-Hydroxy-5-pregnen-20-one) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone can protect the brain from cannabis intoxication[1][2]. Pregnenolone is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels[3].
C20H28O3_12-Oxopimara-9(11),15-dien-18-oic acid
C20H28O3_(8E)-14-Hydroxy-5,9,12,13-tetramethyl-16-methylene-4-oxatricyclo[10.3.1.0~3,5~]hexadeca-1(15),8-dien-2-one
C20H28O3_(5xi,9xi)-12-Oxoabieta-7,13-dien-18-oic acid
C20H28O3_1-Phenanthrenecarboxylic acid, 1,2,3,4,4a,9,10,10a-octahydro-9-hydroxy-1,4a-dimethyl-7-(1-methylethyl)-, (1S,9R)
C20H28O3_7-Hydroxyabieta-8,11,13-trien-18-oic acid
Cafestol
Cafestol is an organic heteropentacyclic compound and furan diterpenoid with formula C20H28O3 obtained from the unsaponifiable fraction of coffee oil (a lipid fraction obtained from coffee beans by organic solvent extraction). It has a role as a plant metabolite, an apoptosis inducer, a hypoglycemic agent, an angiogenesis inhibitor, an antineoplastic agent, an antioxidant and an anti-inflammatory agent. It is an organic heteropentacyclic compound, a tertiary alcohol, a diterpenoid, a member of furans and a primary alcohol. Cafestol is a natural product found in Coffea arabica, Diplospora dubia, and other organisms with data available. An organic heteropentacyclic compound and furan diterpenoid with formula C20H28O3 obtained from the unsaponifiable fraction of coffee oil (a lipid fraction obtained from coffee beans by organic solvent extraction). Cafestol, one of the major components of coffee, is a coffee-specific diterpene from. Cafestol is a ERK inhibitor for AP-1-targeted activity against PGE2 production and the mRNA expression of cyclooxygenase (COX)-2 in LPS-activated RAW264.7 cells. Cafestol has strong inhibitory activity on PGE2 production by suppressing the NF-kB activation pathway. Cafestol contributes to its beneficial effects through various biological activities such as chemopreventive, antitumorigenic, hepatoprotective, antioxidative and antiinflammatory effects[1]. Cafestol, one of the major components of coffee, is a coffee-specific diterpene from. Cafestol is a ERK inhibitor for AP-1-targeted activity against PGE2 production and the mRNA expression of cyclooxygenase (COX)-2 in LPS-activated RAW264.7 cells. Cafestol has strong inhibitory activity on PGE2 production by suppressing the NF-kB activation pathway. Cafestol contributes to its beneficial effects through various biological activities such as chemopreventive, antitumorigenic, hepatoprotective, antioxidative and antiinflammatory effects[1]. Cafestol, one of the major components of coffee, is a coffee-specific diterpene from. Cafestol is a ERK inhibitor for AP-1-targeted activity against PGE2 production and the mRNA expression of cyclooxygenase (COX)-2 in LPS-activated RAW264.7 cells. Cafestol has strong inhibitory activity on PGE2 production by suppressing the NF-kB activation pathway. Cafestol contributes to its beneficial effects through various biological activities such as chemopreventive, antitumorigenic, hepatoprotective, antioxidative and antiinflammatory effects[1].
C20H28O3_(1R,2R,4aR,8aS)-1-[2-(3-Furyl)ethyl]-2,4a,5-trimethyl-1,2,3,4,4a,7,8,8a-octahydro-1-naphthalenecarboxylic acid
C20H28O3_2-Naphthalenecarboxylic acid, 1-[2-(3-furanyl)ethyl]-1,2,3,4,4a,7,8,8a-octahydro-1,4a,5-trimethyl-, (1R,2R,4aR,8aR)
C20H28O3_1-Naphthalenecarboxylic acid, 5-[2-(3-furanyl)ethyl]decahydro-1,4a-dimethyl-6-methylene-, (1S,4aS,5R)
7-(2-hydroxypropan-2-yl)-1,4a-dimethyl-2,3,4,9,10,10a-hexahydrophenanthrene-1-carboxylic acid
9-hydroxy-1,4a-dimethyl-7-propan-2-yl-2,3,4,9,10,10a-hexahydrophenanthrene-1-carboxylic acid
methyl (1S,5R,9S,13R)-5,9-dimethyl-14-methylidenetetracyclo[11.2.1.0¹,¹⁰.0⁴,⁹]hexadecane-5-carboxylate
O-geranylconiferyl alcohol
7-ethenyl-1,4a,7-trimethyl-6-oxo-2,3,4,8,8a,9,10,10a-octahydrophenanthrene-1-carboxylic acid
(1S,4aS,5R)-5-[2-(furan-3-yl)ethyl]-1,4a-dimethyl-6-methylidene-3,4,5,7,8,8a-hexahydro-2H-naphthalene-1-carboxylic acid
Butalamine
C - Cardiovascular system > C04 - Peripheral vasodilators > C04A - Peripheral vasodilators C78274 - Agent Affecting Cardiovascular System > C29707 - Vasodilating Agent D002317 - Cardiovascular Agents > D014665 - Vasodilator Agents
Jatrointelone C from S.guyanensis
3-Hydroxypregn-16-en-20-one
Origin: Animal, Pregnanes
(1S,4aS,5R)-5-[2-(furan-3-yl)ethyl]-1,4a-dimethyl-6-methylidene-3,4,5,7,8,8a-hexahydro-2H-naphthalene-1-carboxylic acid_53.4\\%
(1S,4aS,5R)-5-[2-(furan-3-yl)ethyl]-1,4a-dimethyl-6-methylidene-3,4,5,7,8,8a-hexahydro-2H-naphthalene-1-carboxylic acid_major
(1R,2R,4aR,8aS)-1-[2-(furan-3-yl)ethyl]-2,4a,5-trimethyl-2,3,4,7,8,8a-hexahydronaphthalene-1-carboxylic acid_major
h_267_Isomere_de_oxymetholone_m2
h_315_Oxymetholone_m2
h_68_Calusterone
Isosarcophine
Phytocassane E
16-Pregnolone
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones
(4Z,9a)-9-(3-Methyl-2-butenoyloxy)-4,10(14)-oplopadien-3-one
(4Z,9a)-9-Angeloyloxy-4,10(14)-oplopadien-3-one
Kaurenoic Acid Methyl Ester
5-alpha-Pregnan-3,20-dione
Eicosapentaenoic acid methyl ester
Eicosapentaenoic acid methyl ester is a degradant of a monogalactosyl diacylglycerol (an anticancer compound by inducing apoptosis)[1]. Eicosapentaenoic acid methyl ester is a degradant of a monogalactosyl diacylglycerol (an anticancer compound by inducing apoptosis)[1].
Calusterone
C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C1636 - Therapeutic Steroid Hormone C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C2360 - Anabolic Steroid
ST 21:2;O2
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones > D011372 - Progestins 5a-Pregnane-3,20-dione is the endogenous progesterone metabolite.
4,4,5,5-tetramethyl-2-(4-octylphenyl)-1,3,2-dioxaborolane
4-(4-Ethylpiperazin-1-yl)phenylboronic acid pinacol ester
6-(Cyclohexyl-methylamino)pyridine-3-boronic acid pinacol ester
TRANS-4-BUTYL-4-(4-FLUOROPHENYL)-1,1-BI(CYCLOHEXANE)
1-(TRANS-4-(2-(TRANS-4-ETHYLCYCLOHEXYL)ETHYL)CYCLOHEXYL)-4-FLUOROBENZENE
3-(2,2-DIETHOXY-ETHYLAMINO)-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
tert-Butyl 7-benzyl-2,7-diazaspiro[3.5]nonane-2-carboxylate
tert-butyl 7-benzyl-3,7-diazabicyclo[3.3.1]nonane-3-carboxylate
trans-4-Pentylcyclohexanecarboxylic acid 4-propylphenyl ester
METHYL ABIETATE
1-Benzyl-1,7-diaza-spiro[4.4]nonane-7-carboxylic acid tert-butyl ester
2-Methyl-2-propanyl 5-benzyl-2,5-diazaspiro[3.5]nonane-2-carboxyl ate
1-Methyl-4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl]piperazine
4-Pregnene-3beta-ol-20-one
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones
4-Pentylphenyl trans-4-propylcyclohexanecarboxylate
1-METHYL-4-(3-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)BENZYL)PIPERAZINE
(5alpha,17beta)-17-Methylspiro[androstane-3,3-[3H]diazirin]-17-ol
(5beta,17beta)-17-Methyl-spiro[androstane-3,3-[3H]diazirin]-17-ol
endo-3-{[(1,1-dimethylethoxy)carbonyl]amino}-8-benzyl-8-azabicyclo[3.2.1]octane
2,2,6,6-Bis(tetramethylpiperidine)zinc, lithium chloride complex
3-[(8Z,11Z)-Pentadeca-8,11-dien-1-YL]benzene-1,2-diol
1-[(3S,10R,13S,17S)-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]ethanone
3-Ethynylandrostane-3,17-diol, (3beta,5alpha,17beta)-
Bolasterone
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones > D045930 - Anabolic Agents C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C2360 - Anabolic Steroid Same as: D03144
CMC_13393
C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C1636 - Therapeutic Steroid Hormone D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones COVID info from COVID-19 Disease Map Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS Pregnenolone (3β-Hydroxy-5-pregnen-20-one) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone can protect the brain from cannabis intoxication[1][2]. Pregnenolone is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels[3]. Pregnenolone (3β-Hydroxy-5-pregnen-20-one) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone can protect the brain from cannabis intoxication[1][2]. Pregnenolone is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels[3].
E2012_SIGMA
Eicosapentaenoic acid methyl ester is a degradant of a monogalactosyl diacylglycerol (an anticancer compound by inducing apoptosis)[1]. Eicosapentaenoic acid methyl ester is a degradant of a monogalactosyl diacylglycerol (an anticancer compound by inducing apoptosis)[1].
5beta-Pregnane-3,20-dione
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones
3-(4-((3,7-Dimethylocta-2,6-dien-1-yl)oxy)-3-methoxyphenyl)prop-2-en-1-ol
(2r)-N-[3-(Heptylamino)-3-Oxopropyl]-2,4-Dihydroxy-3,3-Dimethylbutanamide
(1R,5R,12R)-5-ethenyl-13-hydroxy-1,5,12-trimethyl-10-oxatetracyclo[7.6.1.02,7.012,16]hexadec-7-en-11-one
(1beta,14alpha)-1-Hydroxy-14-methyl-13-vinylpodocarp-12-ene-3,11-dione
(3beta,14alpha)-3-Hydroxy-14-methyl-13-vinylpodocarp-12-ene-2,11-dione
(1R,4S,9S,10S,13R)-5,5,9,14-tetramethyl-15-oxapentacyclo[11.3.1.01,10.04,9.014,16]heptadecane-6,7-dione
(1S,5R,9S,13R)-5-formyl-5,9-dimethyltetracyclo[11.2.1.01,10.04,9]hexadec-14-ene-14-carboxylic acid
(1,8a-dimethyl-6-oxo-7-prop-1-en-2-yl-1,2,3,4,7,8-hexahydronaphthalen-2-yl) (E)-2-methylbut-2-enoate
[3-Carboxy-2-(6-methylnonanoyloxy)propyl]-trimethylazanium
[3-Carboxy-2-(5-methylnonanoyloxy)propyl]-trimethylazanium
[3-Carboxy-2-(8-methylnonanoyloxy)propyl]-trimethylazanium
[3-Carboxy-2-(7-methylnonanoyloxy)propyl]-trimethylazanium
[3-Carboxy-2-(4-methylnonanoyloxy)propyl]-trimethylazanium
[3-Carboxy-2-(3-methylnonanoyloxy)propyl]-trimethylazanium
[3-carboxy-2-[(E)-6-hydroxynon-2-enoyl]oxypropyl]-trimethylazanium
[3-carboxy-2-[(E)-6-hydroxynon-7-enoyl]oxypropyl]-trimethylazanium
[3-carboxy-2-[(E)-6-hydroxynon-3-enoyl]oxypropyl]-trimethylazanium
[3-carboxy-2-[(E)-6-hydroxynon-4-enoyl]oxypropyl]-trimethylazanium
[3-carboxy-2-[(Z)-6-hydroxynon-5-enoyl]oxypropyl]-trimethylazanium
[3-carboxy-2-[(Z)-6-hydroxynon-6-enoyl]oxypropyl]-trimethylazanium
[3-Carboxy-2-(7-oxononanoyloxy)propyl]-trimethylazanium
[3-Carboxy-2-(5-oxononanoyloxy)propyl]-trimethylazanium
[3-Carboxy-2-(8-oxononanoyloxy)propyl]-trimethylazanium
[3-Carboxy-2-(3-oxononanoyloxy)propyl]-trimethylazanium
[3-Carboxy-2-(6-oxononanoyloxy)propyl]-trimethylazanium
[3-Carboxy-2-(4-oxononanoyloxy)propyl]-trimethylazanium
[3-Carboxy-2-(9-oxononanoyloxy)propyl]-trimethylazanium
Inumakoic acid
An abietane diterpenoid that is podocarpa-8,11,13-triene substituted by a hydroxy group at position 11, a propan-2-yl group at position 14 and a carboxy group at position 16. It has been isolated from Podocarpus latifolius.
(E)-4-(hept-1-enyl)-7-(3-methylbut-2-enyl)-2,3-dihydrobenzofuran-2,5-diol
A natural product found in Eurotium repens.
2-(Hexylamino)-1-[4-(phenylmethyl)-1-piperidinyl]ethanone
Methyl 8-(pentacyclo[6.4.0.0(2,7).0(3,6).0(9,12)]dodec-4-yl)octanoate
1-[(3S,8R,9R,10R,13S,14S,17S)-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]ethanone
(5R,8R,9S,10S,13S,14S)-17-acetyl-10,13-dimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-one
[(2R)-3-carboxy-2-decanoyloxypropyl]-dimethyl-(trideuteriomethyl)azanium
(2S)-2,6-bis[[(3R)-3-aminobutanoyl]amino]hexanoic acid
(4R)-4,11bbeta-Dimethyl-8-methylene-tetradecahydro-6abeta,9beta-methano-6aH-cyclohepta[a]naphthalene-4beta-carboxylic acid methyl ester
(9E,11E,13E,15E,17E)-henicosa-9,11,13,15,17-pentaenoic acid
1-[(3R,5S,10S,13S)-3-hydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]ethanone
1-[(3S,8S,9R,10R,13S,14S,17R)-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]ethanone
5α-Dihydroprogesterone
A C21-steroid hormone that is 5alpha-pregnane substituted by oxo groups at positions 3 and 20. It is a metabolite of progestrone. D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones 5a-Pregnane-3,20-dione is the endogenous progesterone metabolite.
(20R)-20-hydroxypregn-4-en-3-one
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones > D011372 - Progestins
5beta-pregnane-3,20-dione
A C21-steroid that is 5beta-pregnane with oxo groups at positions 3 and 20.
20-hydroxypregn-4-en-3-one
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones
17beta-Hydroxy-2,17-dimethyl-5alpha-androst-1-en-3-one
JNJ-5207852
JNJ-5207852 is a selective and potent histamine H3 receptor (H3R) antagonist, with pKis of 8.9, 9.24 for rat and human H3R, respectively.
Heneicosapentaenoate (21:5n3)
Heneicosapentaenoic Acid (HPEA) is a polyunsaturated omega-3 fatty acid. Its chemical structure features a 21-carbon long chain with five double bonds located at the 9th, 12th, 15th, 18th, and 21st carbon atoms. This arrangement of double bonds makes it an important component in various biological processes, such as inflammation regulation and cell signaling. However, it’s important to note that HPEA is not as well-known or extensively studied as other omega-3 fatty acids like EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid).
(2s,4as,10ar)-7-(2-methoxypropan-2-yl)-1,1,4a-trimethyl-2,3,4,9,10,10a-hexahydrophenanthren-2-ol
1-{7-hydroxy-9a,11a-dimethyl-1h,2h,3h,3ah,4h,5h,5ah,6h,7h,8h,9h,10h,11h-cyclopenta[a]phenanthren-1-yl}ethanone
methyl (1s,2r,6r,7s,10s,12r,13r,14s)-2,6,12-trimethylpentacyclo[11.2.1.0¹,¹⁰.0²,⁷.0¹²,¹⁴]hexadecane-6-carboxylate
(1s,3as,3br,5ar,9as,9bs,11as)-1-acetyl-9a,11a-dimethyl-tetradecahydrocyclopenta[a]phenanthren-2-one
methyl 2-(4,8,12-trimethylcyclotetradeca-1,3,7,11-tetraen-1-yl)propanoate
1-[(3ar,3bs,5as,7s,9as,9br,11as)-7-hydroxy-9a,11a-dimethyl-3h,3ah,3bh,4h,5h,5ah,6h,7h,8h,9h,9bh,10h,11h-cyclopenta[a]phenanthren-1-yl]ethanone
methyl (1s,4as,4bs,10as)-7-isopropyl-1,4a-dimethyl-2,3,4,4b,5,6,10,10a-octahydrophenanthrene-1-carboxylate
1-[(3as,3br,5as,7s,9as,9bs,11as)-7-hydroxy-9a,11a-dimethyl-3h,3ah,3bh,4h,5h,5ah,6h,7h,8h,9h,9bh,10h,11h-cyclopenta[a]phenanthren-1-yl]ethanone
2-isopropyl-3-methoxy-4b,8,8-trimethyl-5,6,7,8a,9,10-hexahydrophenanthren-4-ol
8-isopropyl-7-methoxy-1,1,4a-trimethyl-2,3,4,9,10,10a-hexahydrophenanthren-9-ol
3-(hexadeca-8,11-dien-1-yl)-5-methylidenefuran-2-one
(2r)-2-methyl-2-(4-methylpent-3-en-1-yl)-7-pentyl-3,4-dihydro-1-benzopyran-5-ol
1-[(1s,3ar,5as,7s,9as,11as)-7-hydroxy-9a,11a-dimethyl-1h,2h,3h,3ah,4h,5h,5ah,6h,7h,8h,9h,10h,11h-cyclopenta[a]phenanthren-1-yl]ethanone
methyl 7-ethenyl-1,4a,7-trimethyl-3,4,6,8,8a,9,10,10a-octahydro-2h-phenanthrene-1-carboxylate
methyl 5-{3a,7b-dimethyl-5-methylidene-octahydrocyclopropa[a]naphthalen-4-yl}-3-methylpent-2-enoate
methyl (1s,4ar,5s,8ar)-1,4a-dimethyl-6-methylidene-5-[(2e)-3-methylpenta-2,4-dien-1-yl]-hexahydro-2h-naphthalene-1-carboxylate
12-o-methylpisiferanol
{"Ingredient_id": "HBIN000949","Ingredient_name": "12-o-methylpisiferanol","Alias": "NA","Ingredient_formula": "C21H32O2","Ingredient_Smile": "CC(C)C1=C(C=C2CC3(CCCC(C3CCC2=C1)(C)C)O)OC","Ingredient_weight": "NA","OB_score": "NA","CAS_id": "NA","SymMap_id": "NA","TCMID_id": "14671","TCMSP_id": "NA","TCM_ID_id": "NA","PubChem_id": "NA","DrugBank_id": "NA"}
1-(3,4-methylenedioxyphenyl)-1e-tetradecene
{"Ingredient_id": "HBIN001032","Ingredient_name": "1-(3,4-methylenedioxyphenyl)-1e-tetradecene","Alias": "NA","Ingredient_formula": "C21H32O2","Ingredient_Smile": "CCCCCCCCCCCCC=CC1=CC2=C(C=C1)OCO2","Ingredient_weight": "NA","OB_score": "NA","CAS_id": "NA","SymMap_id": "NA","TCMID_id": "14375","TCMSP_id": "NA","TCM_ID_id": "NA","PubChem_id": "NA","DrugBank_id": "NA"}
2-{7-[3-(pent-2-en-1-yl)oxiran-2-yl]hepta-2,5-dien-1-yl}-3-(pent-4-en-1-yl)oxirane
1-[(5as)-7-hydroxy-9a,11a-dimethyl-3h,3ah,3bh,4h,5h,5ah,6h,7h,8h,9h,9bh,10h,11h-cyclopenta[a]phenanthren-1-yl]ethanone
(1z,3as,3br,5as,7r,9as,9bs,11as)-1-ethylidene-7-hydroxy-9a,11a-dimethyl-dodecahydro-3h-cyclopenta[a]phenanthren-2-one
methyl (5e,7e,9e,14z,17z)-icosa-5,7,9,14,17-pentaenoate
methyl (1r,4as,5r,8as)-1,4a-dimethyl-6-methylidene-5-[(2e)-3-methylpenta-2,4-dien-1-yl]-hexahydro-2h-naphthalene-1-carboxylate
methyl 1,4a-dimethyl-6-methylidene-5-(3-methylidenepent-4-en-1-yl)-hexahydro-2h-naphthalene-1-carboxylate
(4bs,8as,10r)-1-isopropyl-10-methoxy-4b,8,8-trimethyl-5,6,7,8a,9,10-hexahydrophenanthren-2-ol
1-(1-hydroxyethyl)-9a,11a-dimethyl-1h,2h,3h,3ah,3bh,4h,5h,5ah,6h,9bh,10h,11h-cyclopenta[a]phenanthren-7-one
n-methyl-n-[14-(pyridin-3-yl)tetradec-9-yn-1-yl]hydroxylamine
[(1r,4ar,4bs,7r,10ar)-7-ethenyl-1,4a,7-trimethyl-3,4,4b,5,6,9,10,10a-octahydro-2h-phenanthren-1-yl]methyl formate
methyl 7-ethenyl-1,4a,7-trimethyl-3,4,4b,5,6,9,10,10a-octahydro-2h-phenanthrene-1-carboxylate
methyl (1s,4as,4br,7s,10ar)-7-ethenyl-1,4a,7-trimethyl-3,4,4b,5,6,9,10,10a-octahydro-2h-phenanthrene-1-carboxylate
1-isopropyl-10-methoxy-4b,8,8-trimethyl-5,6,7,8a,9,10-hexahydrophenanthren-2-ol
methyl (2e)-5-[(1as,3ar,4s,7as,7br)-3a,7b-dimethyl-5-methylidene-octahydrocyclopropa[a]naphthalen-4-yl]-3-methylpent-2-enoate
1-ethylidene-7-hydroxy-9a,11a-dimethyl-dodecahydro-3h-cyclopenta[a]phenanthren-2-one
methyl (1s,4ar,5r,8ar)-1,4a-dimethyl-6-methylidene-5-[(2e)-3-methylpenta-2,4-dien-1-yl]-hexahydro-2h-naphthalene-1-carboxylate
methyl (1r,4as,7s,10ar)-7-ethenyl-1,4a,7-trimethyl-3,4,5,6,8,9,10,10a-octahydro-2h-phenanthrene-1-carboxylate
methyl (1r,4ar,4bs,7r,10ar)-7-ethenyl-1,4a,7-trimethyl-3,4,4b,5,6,9,10,10a-octahydro-2h-phenanthrene-1-carboxylate
4-amino-3-[3-(methoxymethyl)-6,7-dimethylocta-2,6-dien-1-yl]benzamide
(1s,3as,3bs,5as,9ar,9bs,11as)-1-[(1s)-1-hydroxyethyl]-9a,11a-dimethyl-1h,2h,3h,3ah,3bh,4h,5h,5ah,6h,9bh,10h,11h-cyclopenta[a]phenanthren-7-one
2-[(1s,6s)-6-isopropyl-3-methylcyclohex-2-en-1-yl]-5-pentylbenzene-1,3-diol
(1r,2s,3s,5r,10r)-5-ethenyl-2,5,11,11-tetramethyl-12-methylidene-15-oxatetracyclo[8.4.1.0¹,¹⁰.0²,⁷]pentadecan-3-ol
(1as,4s,4as,5s,8as)-1a-isopropyl-4,7-dimethyl-5-{[(3z)-3-methylpenta-1,3-dien-2-yl]oxy}-2h,3h,4h,4ah,5h,6h-naphtho[4,4a-b]oxirene
methyl 7-isopropyl-1,4a-dimethyl-2,3,4,5,6,9,10,10a-octahydrophenanthrene-1-carboxylate
methyl (1s,4s,5s,9s,10r,13r)-5,9-dimethyl-14-methylidenetetracyclo[11.2.1.0¹,¹⁰.0⁴,⁹]hexadecane-5-carboxylate
methyl 2-(4,8,12-trimethylcyclotetradeca-3,7,11-trien-1-yl)prop-2-enoate
(4r)-3-{2-[(1r,4ar,8ar)-2,5,5,8a-tetramethyl-1,4,4a,6,7,8-hexahydronaphthalen-1-yl]ethyl}-4-hydroxycyclopent-2-en-1-one
methyl (1r,4ar,7r,8as,10as)-7-ethenyl-1,4a,7-trimethyl-3,4,6,8,8a,9,10,10a-octahydro-2h-phenanthrene-1-carboxylate
methyl 2,6,12-trimethylpentacyclo[11.2.1.0¹,¹⁰.0²,⁷.0¹²,¹⁴]hexadecane-6-carboxylate
methyl 5-(6,8a-dimethyl-2,5-dimethylidene-hexahydro-1h-naphthalen-1-yl)-3-methylpent-2-enoate
2-(octa-2,7-dien-1-yl)-3-{4-[3-(pent-2-en-1-yl)oxiran-2-yl]but-2-en-1-yl}oxirane
methyl (1s,4s,5r,9s,10r,13r)-5,9-dimethyl-14-methylidenetetracyclo[11.2.1.0¹,¹⁰.0⁴,⁹]hexadecane-5-carboxylate
methyl (1r,4ar,7s,8as,10as)-7-ethenyl-1,4a,7-trimethyl-3,4,6,8,8a,9,10,10a-octahydro-2h-phenanthrene-1-carboxylate
methyl (1z,3e,7e,11e)-4-isopropyl-7,11-dimethylcyclotetradeca-1,3,7,11-tetraene-1-carboxylate
(2r,4as,10ar)-7-isopropyl-6-methoxy-1,1,4a-trimethyl-2,3,4,9,10,10a-hexahydrophenanthren-2-ol
1a-isopropyl-4,7-dimethyl-5-[(3-methylpenta-1,3-dien-2-yl)oxy]-2h,3h,4h,4ah,5h,6h-naphtho[4,4a-b]oxirene
2-{5-[4-ethenyl-4-methyl-3-(prop-1-en-2-yl)cyclohexyl]-6-methylidene-2,3-dihydropyran-2-yl}propan-2-ol
methyl 7-ethenyl-1,4a,7-trimethyl-3,4,5,6,8,9,10,10a-octahydro-2h-phenanthrene-1-carboxylate
methoxy[14-(pyridin-3-yl)tetradec-11-yn-1-yl]amine
methyl (4r,4ar,8s,11as,11br)-4,8,9,11b-tetramethyl-1h,2h,3h,4ah,5h,6h,8h,11h,11ah-cyclohepta[a]naphthalene-4-carboxylate
methyl 3-[(1s,2s)-6-isopropyl-1-methyl-2-(prop-1-en-2-yl)-3,4,7,8-tetrahydro-2h-naphthalen-1-yl]propanoate
methyl (2e)-5-[(1s,4as,6r,8ar)-6,8a-dimethyl-2,5-dimethylidene-hexahydro-1h-naphthalen-1-yl]-3-methylpent-2-enoate
methyl (1r,4s,5r,9s,10r,12s)-5,9-dimethyl-13-methylidenetetracyclo[10.2.2.0¹,¹⁰.0⁴,⁹]hexadecane-5-carboxylate
methyl (1r,4ar,4bs,7s,10ar)-7-ethenyl-1,4a,7-trimethyl-3,4,4b,5,6,8,10,10a-octahydro-2h-phenanthrene-1-carboxylate
7-isopropyl-5,6-dimethoxy-1,1-dimethyl-3,4,4a,9,10,10a-hexahydro-2h-phenanthrene
methyl (1r,4s,5r,9s,10r,13s)-5,9,13-trimethyltetracyclo[11.2.1.0¹,¹⁰.0⁴,⁹]hexadec-14-ene-5-carboxylate
methyl (7e,11e)-4-isopropyl-7,11-dimethylcyclotetradeca-1,3,7,11-tetraene-1-carboxylate
2-ethenyl-10-hydroxy-2,4b,8,8,8a-pentamethyl-4,5,6,7,9,10-hexahydro-3h-phenanthren-1-one
methyl 1,4a-dimethyl-6-methylidene-5-(3-methylpenta-2,4-dien-1-yl)-hexahydro-2h-naphthalene-1-carboxylate
(4bs,8as)-2-isopropyl-3-methoxy-4b,8,8-trimethyl-5,6,7,8a,9,10-hexahydrophenanthren-4-ol
1-[(1s,3as,3bs,7s,9ar,9bs,11ar)-7-hydroxy-9a,11a-dimethyl-1h,2h,3h,3ah,3bh,4h,6h,7h,8h,9h,9bh,10h,11h-cyclopenta[a]phenanthren-1-yl]ethanone
(2r,4as,10as)-7-isopropyl-6-methoxy-1,1,4a-trimethyl-2,3,4,9,10,10a-hexahydrophenanthren-2-ol
methyl (5z,7e,9e,14z,17z)-icosa-5,7,9,14,17-pentaenoate
methyl 4,8,9,11b-tetramethyl-1h,2h,3h,4ah,5h,6h,8h,11h,11ah-cyclohepta[a]naphthalene-4-carboxylate
5-{2-[(1r,2r,4as,8as)-1,2,4a-trimethyl-5-methylidene-hexahydro-2h-naphthalen-1-yl]ethyl}-3,6-dihydropyran-2-one
3-[(8z,11z)-hexadeca-8,11-dien-1-yl]-5-methylidenefuran-2-one
methyl (1s,4as,5r,8as)-1,4a-dimethyl-6-methylidene-5-(3-methylidenepent-4-en-1-yl)-hexahydro-2h-naphthalene-1-carboxylate
6-isopropyl-5-methoxy-12,12-dimethyltricyclo[9.4.0.0³,⁸]pentadeca-3(8),4,6-trien-1-ol
methyl 5,9-dimethyl-13-methylidenetetracyclo[10.2.2.0¹,¹⁰.0⁴,⁹]hexadecane-5-carboxylate
5-[2-(1,2,4a-trimethyl-5-methylidene-hexahydro-2h-naphthalen-1-yl)ethyl]-3,6-dihydropyran-2-one
(3as,3br,5as,7r,9as,9bs,11as)-1-ethylidene-7-hydroxy-9a,11a-dimethyl-dodecahydro-3h-cyclopenta[a]phenanthren-2-one
methyl 2-[(1s,3e,7e,11e)-4,8,12-trimethylcyclotetradeca-3,7,11-trien-1-yl]prop-2-enoate
methyl (2s)-2-[(1e,3e,7e,11e)-4,8,12-trimethylcyclotetradeca-1,3,7,11-tetraen-1-yl]propanoate
1-{7-hydroxy-9a,11a-dimethyl-3h,3ah,3bh,4h,5h,5ah,6h,7h,8h,9h,9bh,10h,11h-cyclopenta[a]phenanthren-1-yl}ethanone
methyl 5,9,13-trimethyltetracyclo[11.2.1.0¹,¹⁰.0⁴,⁹]hexadec-14-ene-5-carboxylate
(2r,3r)-2-[(2z,5z)-7-[(2r,3r)-3-[(2z)-pent-2-en-1-yl]oxiran-2-yl]hepta-2,5-dien-1-yl]-3-(pent-4-en-1-yl)oxirane
(1r,4ar,7s,10ar)-7-ethenyl-1,4a,7,10a-tetramethyl-2,3,4,5,6,8,9,10-octahydrophenanthrene-1-carboxylic acid
methyl (6z,9z,12z,15z,18z)-icosa-6,9,12,15,18-pentaenoate
(2s,4br,8as,10s)-2-ethenyl-10-hydroxy-2,4b,8,8,8a-pentamethyl-4,5,6,7,9,10-hexahydro-3h-phenanthren-1-one
2-methyl-2-(4-methylpent-3-en-1-yl)-7-pentyl-3,4-dihydro-1-benzopyran-5-ol
1-(1-hydroxyethyl)-9a,11a-dimethyl-1h,2h,3h,3ah,3bh,4h,5h,8h,9h,9bh,10h,11h-cyclopenta[a]phenanthren-7-one
methyl (1r,4ar,7s,8ar,10as)-7-ethenyl-1,4a,7-trimethyl-3,4,6,8,8a,9,10,10a-octahydro-2h-phenanthrene-1-carboxylate
(4as,9s,10as)-8-isopropyl-7-methoxy-1,1,4a-trimethyl-2,3,4,9,10,10a-hexahydrophenanthren-9-ol
2-[(2r)-5-[(1s,3r,4r)-4-ethenyl-4-methyl-3-(prop-1-en-2-yl)cyclohexyl]-6-methylidene-2,3-dihydropyran-2-yl]propan-2-ol
methyl 7-ethenyl-1,4a,7-trimethyl-3,4,4b,5,6,8,10,10a-octahydro-2h-phenanthrene-1-carboxylate
(4bs,8as,10s)-1-isopropyl-10-methoxy-4b,8,8-trimethyl-5,6,7,8a,9,10-hexahydrophenanthren-2-ol
(7-ethenyl-1,4a,7-trimethyl-3,4,4b,5,6,9,10,10a-octahydro-2h-phenanthren-1-yl)methyl formate
methyl (1s,4ar,4bs,7s,10ar)-7-ethenyl-1,4a,7-trimethyl-3,4,4b,5,6,8,10,10a-octahydro-2h-phenanthrene-1-carboxylate
(1e,3as,3br,5as,7r,9as,9bs,11as)-1-ethylidene-7-hydroxy-9a,11a-dimethyl-dodecahydro-3h-cyclopenta[a]phenanthren-2-one
(3e,6r,7e,9e)-17-(furan-2-yl)heptadeca-3,7,9-trien-6-ol
7-isopropyl-6-methoxy-1,1,4a-trimethyl-2,3,4,9,10,10a-hexahydrophenanthren-2-ol
(2r,3s)-2-[(2z)-octa-2,7-dien-1-yl]-3-[(2z)-4-[(2s,3r)-3-[(2z)-pent-2-en-1-yl]oxiran-2-yl]but-2-en-1-yl]oxirane
methyl (1r,4as,4br,7r,10as)-7-ethenyl-1,4a,7-trimethyl-3,4,4b,5,6,9,10,10a-octahydro-2h-phenanthrene-1-carboxylate
(1s,11s)-6-isopropyl-5-methoxy-12,12-dimethyltricyclo[9.4.0.0³,⁸]pentadeca-3(8),4,6-trien-1-ol
methyl (1r,4ar,5r,8ar)-1,4a-dimethyl-6-methylidene-5-(3-methylidenepent-4-en-1-yl)-hexahydro-2h-naphthalene-1-carboxylate
3-[2-(2,5,5,8a-tetramethyl-1,4,4a,6,7,8-hexahydronaphthalen-1-yl)ethyl]-4-hydroxycyclopent-2-en-1-one
methyl (1r,4as,4br,7s,10as)-7-ethenyl-1,4a,7-trimethyl-3,4,4b,5,6,8,10,10a-octahydro-2h-phenanthrene-1-carboxylate
5-ethenyl-2,5,11,11-tetramethyl-12-methylidene-15-oxatetracyclo[8.4.1.0¹,¹⁰.0²,⁷]pentadecan-3-ol
(1s,3as,3br,9as,9bs,11as)-1-[(1s)-1-hydroxyethyl]-9a,11a-dimethyl-1h,2h,3h,3ah,3bh,4h,5h,8h,9h,9bh,10h,11h-cyclopenta[a]phenanthren-7-one
4-amino-3-[(2z)-3-(methoxymethyl)-6,7-dimethylocta-2,6-dien-1-yl]benzamide
7-ethenyl-1,4a,7,10a-tetramethyl-2,3,4,5,6,8,9,10-octahydrophenanthrene-1-carboxylic acid
methyl 3-[6-isopropyl-1-methyl-2-(prop-1-en-2-yl)-3,4,7,8-tetrahydro-2h-naphthalen-1-yl]propanoate
DG(5:0_9:0)
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DG(8:0_6:0)
Provides by LipidSearch Vendor. © Copyright 2006-2024 Thermo Fisher Scientific Inc. All rights reserved
