Exact Mass: 310.10524780000003
Exact Mass Matches: 310.10524780000003
Found 500 metabolites which its exact mass value is equals to given mass value 310.10524780000003,
within given mass tolerance error 0.05 dalton. Try search metabolite list with more accurate mass tolerance error
0.01 dalton.
Picrotin
Picrotin is an organic heteropentacyclic compound that is picrotoxinin in which the olefinic double bond has undergone addition of water to give the corresponding tertiary alcohol. It is the less toxic component of picrotoxin, lacking GABA activity. It has a role as a plant metabolite. It is an organic heteropentacyclic compound, an epoxide, a tertiary alcohol, a gamma-lactone, a diol and a picrotoxane sesquiterpenoid. It is functionally related to a picrotoxinin. Picrotin is a natural product found in Dendrobium moniliforme and Anamirta cocculus with data available. Picrotin belongs to the class of organic compounds known as furopyrans. These are organic polycyclic compounds containing a furan ring fused to a pyran ring. Furan is a five-membered aromatic ring with four carbon atoms and one oxygen atom. Pyran a six-membered heterocyclic, non-aromatic ring, made up of five carbon atoms and one oxygen atom and containing two double bonds. Picrotin is soluble (in water) and a very weakly acidic compound (based on its pKa). C78272 - Agent Affecting Nervous System > C47795 - CNS Stimulant Picrotin is an active compound, also is one of the composition of picrotoxin (an antagonist of GABAA receptors (GABAARs) and glycine receptors (GlyRs)). Picrotin has sensitivity for GlyRs/b> with IC50 values range from 5.2 μM to 106 μM. Picrotin can be used for the research of neurotransmission[1][2]. Picrotin is an active compound, also is one of the composition of picrotoxin (an antagonist of GABAA receptors (GABAARs) and glycine receptors (GlyRs)). Picrotin has sensitivity for GlyRs/b> with IC50 values range from 5.2 μM to 106 μM. Picrotin can be used for the research of neurotransmission[1][2]. Picrotin is an active compound, also is one of the composition of picrotoxin (an antagonist of GABAA receptors (GABAARs) and glycine receptors (GlyRs)). Picrotin has sensitivity for GlyRs/b> with IC50 values range from 5.2 μM to 106 μM. Picrotin can be used for the research of neurotransmission[1][2].
6-Deoxyjacareubin
6-Deoxyjacareubin is a member of pyranoxanthones. 6-Deoxyjacareubin is a natural product found in Mourera fluviatilis, Hypericum brasiliense, and other organisms with data available.
Sulfadoxine
C12H14N4O4S (310.07357240000005)
Sulfadoxine is only found in individuals that have used or taken this drug. It is a long acting sulfonamide that is used, usually in combination with other drugs, for respiratory, urinary tract, and malarial infections. [PubChem]Sulfadoxine is a sulfa drug, often used in combination with pyrimethamine to treat malaria. This medicine may also be used to prevent malaria in people who are living in, or will be traveling to, an area where there is a chance of getting malaria. Sulfadoxine targets Plasmodium dihydropteroate synthase and dihydrofolate reductase. Sulfa drugs or Sulfonamides are antimetabolites. They compete with para-aminobenzoic acid (PABA) for incorporation into folic acid. The action of sulfonamides exploits the difference between mammal cells and other kinds of cells in their folic acid metabolism. All cells require folic acid for growth. Folic acid (as a vitamin) diffuses or is transported into human cells. However, folic acid cannot cross bacterial (and certain protozoan) cell walls by diffusion or active transport. For this reason bacteria must synthesize folic acid from p-aminobenzoic acid. D000890 - Anti-Infective Agents > D000977 - Antiparasitic Agents > D000981 - Antiprotozoal Agents C254 - Anti-Infective Agent > C276 - Antiparasitic Agent > C277 - Antiprotozoal Agent D000890 - Anti-Infective Agents > D013424 - Sulfanilamides CONFIDENCE standard compound; INTERNAL_ID 1010
trans-cinnamoyl-beta-D-glucoside
Trans-cinnamoyl-beta-d-glucoside, also known as 1-O-trans-cinnamoyl-beta-D-glucopyranose, is a member of the class of compounds known as O-cinnamoyl glycosides. O-cinnamoyl glycosides are o-glycoside derivatives of cinnamic acid. Cinnamic acid is an aromatic compound containing a benzene and a carboxylic acid group forming 3-phenylprop-2-enoic acid. Trans-cinnamoyl-beta-d-glucoside is slightly soluble (in water) and a very weakly acidic compound (based on its pKa). Trans-cinnamoyl-beta-d-glucoside can be found in a number of food items such as angelica, cherry tomato, garden cress, and yam, which makes trans-cinnamoyl-beta-d-glucoside a potential biomarker for the consumption of these food products. Trans-cinnamoyl-β-d-glucoside, also known as 1-O-trans-cinnamoyl-beta-D-glucopyranose, is a member of the class of compounds known as O-cinnamoyl glycosides. O-cinnamoyl glycosides are o-glycoside derivatives of cinnamic acid. Cinnamic acid is an aromatic compound containing a benzene and a carboxylic acid group forming 3-phenylprop-2-enoic acid. Trans-cinnamoyl-β-d-glucoside is slightly soluble (in water) and a very weakly acidic compound (based on its pKa). Trans-cinnamoyl-β-d-glucoside can be found in a number of food items such as angelica, cherry tomato, garden cress, and yam, which makes trans-cinnamoyl-β-d-glucoside a potential biomarker for the consumption of these food products.
Pentaporphyrin I
Pentaporphyrin I is a porphyrin intermediate detected in liver, kidney and erythrocytes (PubMed ID 8803328 ).
7-Hydroxy-3-(4-methoxyphenyl)-4-propylcoumarin
Mannopine
A hexitol derivative that is D-mannitol in which the hydroxy group at position 1 is replaced by the alpha-amino group of L-glutamine. It is produced in crown gall tumours induced in a wide range of dicotyledenous plants by Agrobacterium tumefaciens.
Acromelic acid A
A pyrrolidinecarboxylic acid that is siolated from the poisonous mushroom Clitocybe amoenolens.
Moracin C
Moracin C is a member of benzofurans. Moracin C is a natural product found in Morus mesozygia, Morus alba var. multicaulis, and other organisms with data available. Isolated from Morus alba (white mulberry) infected with Fusarium solani. Moracin C is found in mulberry and fruits. Moracin C is found in fruits. Moracin C is isolated from Morus alba (white mulberry) infected with Fusarium solani. Moracin C, a natural product, is an anti-inflammatory agent. Moracin C inhibits LPS-activated reactive oxygen species (ROS) and nitric oxide (NO) release from cells[1]. Moracin C, a natural product, is an anti-inflammatory agent. Moracin C inhibits LPS-activated reactive oxygen species (ROS) and nitric oxide (NO) release from cells[1].
Hydroxytanshinone
Hydroxytanshinone is an abietane diterpenoid. Hydroxytanshinone is a natural product found in Salvia przewalskii and Salvia sclarea with data available. Minor constituent of Salvia sclarea (clary sage). Hydroxytanshinone is found in tea, alcoholic beverages, and herbs and spices. Hydroxytanshinone is found in alcoholic beverages. Hydroxytanshinone is a minor constituent of Salvia sclarea (clary sage).
Sulfadimethoxine
C12H14N4O4S (310.07357240000005)
Sulfadimethoxine (trade name Di-Methox, Albon) is a sulfonamide antibiotic. Sulfadimethoxine is used to treat many infections including treatment of respiratory, urinary tract, enteric, and soft tissue infections. It is most frequently used in veterinary medicine, although it is approved in some countries for use in humans. Sulfadimethoxine inhibits bacterial synthesis of folic acid (pteroylglutamic acid) from para-aminobenzoic acid. J - Antiinfectives for systemic use > J01 - Antibacterials for systemic use > J01E - Sulfonamides and trimethoprim > J01ED - Long-acting sulfonamides Long-acting sulfonamide, antibacterial agent. Potential food contaminant in animal products arising from its veterinary use C254 - Anti-Infective Agent > C29739 - Sulfonamide Anti-Infective Agent D000890 - Anti-Infective Agents > D013424 - Sulfanilamides
Desloratadine
Desloratadine is a second generation, tricyclic antihistamine that which has a selective and peripheral H1-antagonist action. It is the active descarboethoxy metabolite of loratidine (a second generation histamine). Desloratidine has a long-lasting effect and does not cause drowsiness because it does not readily enter the central nervous system. R - Respiratory system > R06 - Antihistamines for systemic use > R06A - Antihistamines for systemic use D018377 - Neurotransmitter Agents > D018678 - Cholinergic Agents > D018680 - Cholinergic Antagonists D018377 - Neurotransmitter Agents > D018494 - Histamine Agents > D006633 - Histamine Antagonists C308 - Immunotherapeutic Agent > C29578 - Histamine-1 Receptor Antagonist Desloratadine (Sch34117) is the orally active major metabolite of the nonsedating H1-antihistamine Loratadine. Desloratadine is a selective H1-receptor antagonist that has anti-allergic and anti-inflammatory activities[1][2]. Desloratadine (Sch34117) is the orally active major metabolite of the nonsedating H1-antihistamine Loratadine. Desloratadine is a selective H1-receptor antagonist that has anti-allergic and anti-inflammatory activities[1][2].
Glutamyltyrosine
Glutamyltyrosine is a dipeptide composed of glutamate and tyrosine, and is a proteolytic breakdown product of larger proteins. It belongs to the family of N-acyl-alpha amino acids and derivatives. These are compounds containing an alpha amino acid which bears an acyl group at its terminal nitrogen atom. Glutamyltyrosine is an incomplete breakdown product of protein digestion or protein catabolism. Some dipeptides are known to have physiological or cell-signaling effects although most are simply short-lived intermediates on their way to specific amino acid degradation pathways following further proteolysis. Glutamyltyrosine, also known as alpha-glu-tyr or E-Y, is a member of the class of compounds known as dipeptides. Dipeptides are organic compounds containing a sequence of exactly two alpha-amino acids joined by a peptide bond. Glutamyltyrosine is practically insoluble (in water) and a weakly acidic compound (based on its pKa). Glutamyltyrosine can be found in soy bean, which makes glutamyltyrosine a potential biomarker for the consumption of this food product. Glutamyltyrosine can be found primarily in feces.
Gamma-glutamyltyrosine
gamma-Glutamyltyrosine is a dipeptide composed of gamma-glutamate and tyrosine, and is a proteolytic breakdown product of larger proteins. It belongs to the family of N-acyl-alpha amino acids and derivatives. These are compounds containing an alpha amino acid which bears an acyl group at its terminal nitrogen atom. gamma-Glutamyltyrosine is an incomplete breakdown product of protein digestion or protein catabolism. Some dipeptides are known to have physiological or cell-signaling effects although most are simply short-lived intermediates on their way to specific amino acid degradation pathways following further proteolysis. γ-Glu-Tyr, a competitive inhibitor of dipeptidyl peptidase-IV (DPP-IV) (IC50=6.77 mM), is a potentially functional component of the type 2 diabetes diet[1].
(E)-1-O-Cinnamoyl-beta-D-glucose
(E)-1-O-Cinnamoyl-beta-D-glucose is found in fruits. (E)-1-O-Cinnamoyl-beta-D-glucose is a constituent of Vaccinium vitis-idaea (cowberry)
Artocarbene
Artocarbene is found in fruits. Artocarbene is a constituent of Artocarpus incisus (breadfruit)
4-(4'-O-Acetyl-alpha-L-rhamnosyloxy)benzaldehyde
4-(4-O-Acetyl-alpha-L-rhamnosyloxy)benzaldehyde has been isolated from the leaves of Moringa oleifera (horseradish tree). It is found in fats and oils as well as in herbs and spices. Isolated from Moringa oleifera (horseradish tree). 1-Pentadecanecarboxylic acid is found in fats and oils and herbs and spices.
Moracin N
Moracin N is found in fruits. Moracin N is a constituent of the leaves of Morus alba (white mulberry) (famine food). Constituent of the leaves of Morus alba (white mulberry) (famine food). Moracin N is found in mulberry and fruits.
(E)-2-O-Cinnamoyl-beta-D-glucopyranose
(E)-2-O-Cinnamoyl-beta-D-glucopyranose is found in green vegetables. (E)-2-O-Cinnamoyl-beta-D-glucopyranose is a constituent of commercial rhubarb, Rheum sp Constituent of commercial rhubarb, Rheum species (E)-2-O-Cinnamoyl-beta-D-glucopyranose is found in green vegetables.
6,11-Dihydroxy-2,2-dimethylpyrano[3,2-c]xanthen-7(2H)-one
6,11-Dihydroxy-2,2-dimethylpyrano[3,2-c]xanthen-7(2H)-one is found in fruits. 6,11-Dihydroxy-2,2-dimethylpyrano[3,2-c]xanthen-7(2H)-one is a constituent of the root bark of Garcinia livingstonei (imbe). Constituent of the root bark of Garcinia livingstonei (imbe). 6,11-Dihydroxy-2,2-dimethylpyrano[3,2-c]xanthen-7(2H)-one is found in fruits.
Tyrosyl-Glutamate
Tyrosyl-Glutamate is a dipeptide composed of tyrosine and glutamate. It is an incomplete breakdown product of protein digestion or protein catabolism. Some dipeptides are known to have physiological or cell-signaling effects although most are simply short-lived intermediates on their way to specific amino acid degradation pathways following further proteolysis. This dipeptide has not yet been identified in human tissues or biofluids and so it is classified as an Expected metabolite.
N-(Dimethylamino)methylene-9-((2-hydroxy-1-(hydroxymethyl)ethoxy)methyl)guanine
C12H18N6O4 (310.13894680000004)
2-[(4-Oxo-3-phenyl-4H-chromen-7-YL)oxy]propanoic acid
Cl-amidine
C14H19ClN4O2 (310.11964639999997)
EMycin E
Mabuterol
D019141 - Respiratory System Agents > D018927 - Anti-Asthmatic Agents > D001993 - Bronchodilator Agents C78272 - Agent Affecting Nervous System > C29747 - Adrenergic Agent > C87053 - Adrenergic Agonist D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents > D000322 - Adrenergic Agonists D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents
Porphycene
3-(2,4-Dimethyl-5-(2-oxo-1,2-dihydroindol-3-ylidenemethyl)-1H-pyrrol-3-yl)propionic acid
D004791 - Enzyme Inhibitors > D047428 - Protein Kinase Inhibitors
Tanshinone IIb
Valine-betaxanthin
Przewaquinone A
Przewaquinone A is a natural product found in Salvia densiflora, Salvia miltiorrhiza, and other organisms with data available.
7-(2,3-Dihydroxy-3-methylbutyloxy)-5-hydroxy-6-methoxycoumarin
8,11-dihydroxy-2,2-dimethylpyrano[3,2-c]xanthen-7(2H)-one
Obolactone
A pyranone isolated from the trunk barks of Cryptocarya obovata and has been shown to exhibit cytotoxicity against the KB cell line.
Mabuterol
D019141 - Respiratory System Agents > D018927 - Anti-Asthmatic Agents > D001993 - Bronchodilator Agents C78272 - Agent Affecting Nervous System > C29747 - Adrenergic Agent > C87053 - Adrenergic Agonist D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents > D000322 - Adrenergic Agonists D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents CONFIDENCE standard compound; INTERNAL_ID 1102
4-Amino-2-{[4-methyl-5-(4-pyridinyl)-4H-1,2,4-triazol-3-yl]sulfanyl}-5-pyrimidinecarbonitrile
C13H10N8S (310.07491000000005)
6-Hydroxy-2-(2-phenylethyl)-chromone6-Me ether3-methoxy
2H,6H-Pyrano(3,2-b)xanthen-6-one, 7,12-dihydroxy-2,2-dimethyl-
3,7-dimethylgalangin|5-hydroxy-3,7-dimethoxyflavone
3-O-alpha-L-Rhamnopyranosyl-L-rhamnose|alpha-Pyranose-form-3-O-alpha-L-Rhamnopyranosyl-L-rhamnose
Emycin E
D004791 - Enzyme Inhibitors > D011500 - Protein Synthesis Inhibitors D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents D005765 - Gastrointestinal Agents
(3R*,4S*,5E,8S*,10S*)-3,8-epoxy-3,4,13-trihydroxy-1-oxogermacra-5,7(11)-dien-6,12-olide|potamopholide
12-Oxa-9,20-cyclo-9,10-secoabieta-1,5,8,10(20),13-pentene-3,7,11-trione
(E)-cinnamyl (E)-isoferulate|(E)-cinnamyl-(E)-isoferulate|cinnamyl isoferulate
4-Amino-7-(b-D-ribofuranosyl)-7H-pyrrolo[2.3-d]pyrimidine-5-carboxylic acid
2,3-dihydroxy-2-(2-hydroxy-4-methyl-5-methoxyphenyl)propyl tiglate
2,9-Dihydroxy-dibenz[a,h]anthracen|Dibenz[a,h]anthracen-2,9-diol|dibenz[a,h]anthracene-2,9-diol
3-(methoxycarbonyl)-2,4-diphenylcyclobutanecarboxylic acid
Isobutyric acid 2-hydroxy-2-[2-hydroxy-4-(acetoxymethyl)phenyl]propyl ester
2-(2-hydroxy-4-methoxyphenyl)-7-methoxy-5-(E)-propenylbenzofuran|Toltecol
1beta,4alpha-dihydroxy-2alpha,3alpha-epoxy-8beta-methoxy-eudesma-7(11)-en-8alpha,12-olide
3alpha-Hydroxytanshinone IIA|3??-Hydroxytanshinone IIA
Me glycoside-alpha-Pyranose-4-O-alpha-L-Rhamnopyranosyl-D-xylose
3-(Acetyloxy)-2-hydroxy-2-(2-hydroxy-4-methylphenyl)propyl 2-methylpropanoate #
Anolignan A
A lignan that consists of buta-1,3-diene substituted by a 2,4-dihydroxybenzyl group at position 2 and a 1,3-benzodioxol-5-ylmethyl group at position 3. It is isolated from the ground stems of Anogeissus acuminata and exhibits anti-HIV activity by inhibiting HIV-1 reverse transcriptase enzyme.
(2,3-trans-3,4-trans)-3,4-Dimethoxy-(2,3:7,8)-furanoflavan
fusarentin 4,5-dimethyl ether|fusarentin 6,7-dimethyl ether|Fusarentin-dimethylether
9-Tigloyl,2-Me ether-p-Mentha-1,3,5-triene-2,5,8,9,10-pentol
5-hydroxy-6-(1,1-dimethylallyl)oroselone|Hortiolon
10beta-methoxy-1alpha,11beta,13-tetrahydrolactucin
2beta,3beta-dihydroxy-11beta,13-dihydrodeoxymikanolide
3-Methyl-6-hydroxy-8-(beta-hydroxyphenethyl)-2,5-dihydro-1-benzooxepin-5-one
5-methoxy-6,8,8-trimethyl-2-phenylchromene-4,7-dione|5-methoxydasytrichone|5-methoxydesmosdomutin
methyl (2R,3R,4R,4aS,7aR)-3-hydroxy-4-[(S)-1-hydroxyethyl]-5-oxo-3,4,4a,7a-tetrahydro-1H,5H-spiro[cyclopenta[c]pyran-7,2-furan]-4-carboxylate|plumeridoid C
6-hydroxy-2-[2-(4-hydroxy-3-methoxyphenyl)ethenyl]chromone
(4E,6E)-1-(3,4-dihydroxyphenyl)-7-(4-hydroxyphenyl)-hepta-4,6-dien-3-one|1-(4-hydroxyphenyl)-7-(3,4-dihydroxyphenyl)-hepta-(4E,6E)-4,6-dien-3-one
(E)-2-methylbut-2-ene-1,4-diyl dibenzoate|uvaridacane A
1-{2-[(1E)-1-(5-chloro-1H-pyrrol-2-yl)prop-1-en-2-yl]-1,3-oxazol-4-yl}-2-methylbutane-1,3-diol|Pyrronazol C1
(E)-3,5-dimethoxy-4-[6-(prop-1-enyl)benzofuran-2-yl]phenol
Picrotin
relative retention time with respect to 9-anthracene Carboxylic Acid is 0.508 relative retention time with respect to 9-anthracene Carboxylic Acid is 0.502 relative retention time with respect to 9-anthracene Carboxylic Acid is 0.503 Picrotin is an active compound, also is one of the composition of picrotoxin (an antagonist of GABAA receptors (GABAARs) and glycine receptors (GlyRs)). Picrotin has sensitivity for GlyRs/b> with IC50 values range from 5.2 μM to 106 μM. Picrotin can be used for the research of neurotransmission[1][2]. Picrotin is an active compound, also is one of the composition of picrotoxin (an antagonist of GABAA receptors (GABAARs) and glycine receptors (GlyRs)). Picrotin has sensitivity for GlyRs/b> with IC50 values range from 5.2 μM to 106 μM. Picrotin can be used for the research of neurotransmission[1][2]. Picrotin is an active compound, also is one of the composition of picrotoxin (an antagonist of GABAA receptors (GABAARs) and glycine receptors (GlyRs)). Picrotin has sensitivity for GlyRs/b> with IC50 values range from 5.2 μM to 106 μM. Picrotin can be used for the research of neurotransmission[1][2].
6-O-cinnamoyl-D-glucopyranose|6-O-cinnamoyl-D-glucopyranose|6-O-cinnamoylglucose
ortho-[(5-hydroxy)-cis-cinnamoyl]-trans-cinnamic acid
(E)-5-(6-hydroxybenzofuran-2-yl)-4-(3-methylbut-1-enyl)benzene-1,3-diol
Me glycoside-alpha-Pyranose-2-O-alpha-Rhamnopyranosyl-L-arabinose|My glycoside-beta-Pyranose-2-O-alpha-Rhamnopyranosyl-L-arabinose
5-Hydroxy-6-methoxy-7-(2,3-dihydroxy-3-methylbutoxy)coumarin
Digilanidobiose|O4-beta-D-glucopyranosyl-D-ribo-2,6-dideoxy-hexose|O4-beta-D-Glucopyranosyl-D-ribo-2,6-didesoxy-hexose
(3E)-3-(1,3-benzodioxol-5-ylmethylene)-2,3-dihydro-7-methoxy-4H-1-benzopyran-4-one
2-(2-hydroxy- 4,6-dimethoxyphenyl)-5-[(E)-propenyl]benzofuran|2-(2-hydroxy-4,6-dimethoxyphenyl)-5-(E)-propenylbenzofuran|2-(4,6-dimethoxyphenyl-2-hydroxyphenyl)-5-(E)-propenylbenzofuran
N-(1-hydroxy-5-oxocyclopent-1-enyl)-7-(3-aminophenyl)hepta-2,4,6-trienamide
4-(3-hydroxybutanoyl)-2-[(1E,3E)-5-hydroxyhexa-1,3-dien-1-yl]-5-methoxy-2-methylfuran-3(2H)-one|penicilliol B
6-Me ether,7-methoxy-6-Hydroxy-2-(2-phenylethyl)-4H-1-benzopyran-4-one
4H-1-Benzopyran-4-one, 6-methoxy-2-(2-(4-methoxyphenyl)ethyl)-
N-[1-(Aminocarbonyl)-4-[(2-chloro-1-iminoethyl)amino]butyl]-benzamide
C14H19ClN4O2 (310.11964639999997)
Tanshinone IIA anhydride
TTE-50
(S)-6-(Hydroxymethyl)-1,6-dimethyl-6,7,8,9-tetrahydrophenanthro[1,2-b]furan-10,11-dione is a natural product found in Salvia miltiorrhiza with data available. D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents D007155 - Immunologic Factors > D007166 - Immunosuppressive Agents D002491 - Central Nervous System Agents > D000700 - Analgesics D006401 - Hematologic Agents > D000925 - Anticoagulants D000893 - Anti-Inflammatory Agents D000890 - Anti-Infective Agents D000970 - Antineoplastic Agents D018501 - Antirheumatic Agents
sulfadimethoxine
C12H14N4O4S (310.07357240000005)
J - Antiinfectives for systemic use > J01 - Antibacterials for systemic use > J01E - Sulfonamides and trimethoprim > J01ED - Long-acting sulfonamides A sulfonamide consisting of pyrimidine having methoxy substituents at the 2- and 6-positions and a 4-aminobenzenesulfonamido group at the 4-position. C254 - Anti-Infective Agent > C29739 - Sulfonamide Anti-Infective Agent D000890 - Anti-Infective Agents > D013424 - Sulfanilamides CONFIDENCE standard compound; INTERNAL_ID 2363 CONFIDENCE standard compound; INTERNAL_ID 8542 CONFIDENCE standard compound; EAWAG_UCHEM_ID 183 CONFIDENCE standard compound; INTERNAL_ID 1009
gamma-Glutamyltyrosine
γ-Glu-Tyr, a competitive inhibitor of dipeptidyl peptidase-IV (DPP-IV) (IC50=6.77 mM), is a potentially functional component of the type 2 diabetes diet[1].
Desloratadine
Loratadine in which the ethoxycarbonyl group attached to the piperidine ring is replaced by hydrogen. The major metabolite of loratidine, desloratadine is an antihistamine which is used for the symptomatic relief of allergic conditions including rhinitis and chronic urticaria. It does not readily enter the central nervous system, so does not cause drowsiness. R - Respiratory system > R06 - Antihistamines for systemic use > R06A - Antihistamines for systemic use D018377 - Neurotransmitter Agents > D018678 - Cholinergic Agents > D018680 - Cholinergic Antagonists D018377 - Neurotransmitter Agents > D018494 - Histamine Agents > D006633 - Histamine Antagonists C308 - Immunotherapeutic Agent > C29578 - Histamine-1 Receptor Antagonist CONFIDENCE standard compound; INTERNAL_ID 2704 CONFIDENCE standard compound; INTERNAL_ID 8597 Desloratadine (Sch34117) is the orally active major metabolite of the nonsedating H1-antihistamine Loratadine. Desloratadine is a selective H1-receptor antagonist that has anti-allergic and anti-inflammatory activities[1][2]. Desloratadine (Sch34117) is the orally active major metabolite of the nonsedating H1-antihistamine Loratadine. Desloratadine is a selective H1-receptor antagonist that has anti-allergic and anti-inflammatory activities[1][2].
1,7,8-trihydroxy-3-methyl-2,3,4,7-tetrahydro-1H-benzo[a]anthracen-12-one
3-methoxy-1-(4-methoxy-1-benzofuran-5-yl)-3-phenylpropan-1-one
[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl] (E)-3-phenylprop-2-enoate
C17H14N2O4_Spiro[3H-1,4-benzodiazepine-3,2-oxirane]-2,5(1H,4H)-dione, 3-(3-hydroxyphenyl)-4-methyl-, (3S,3R)
gamma-Glu-tyr
A dipeptide composed of L-glutamic acid and L-tyrosine joined by a peptide linkage.
(3S,3R)-3-(3-hydroxyphenyl)-4-methylspiro[1H-1,4-benzodiazepine-3,2-oxirane]-2,5-dione
1,7,8-trihydroxy-3-methyl-2,3,4,7-tetrahydro-1H-benzo[a]anthracen-12-one
Lymphostin
A member of the class of pyrroloquinolines that is pyrrolo[4,3,2-de]quinoline in which the hydrogens at positions 4, 6 and 8 are replaced by (1E)-1-methoxy-3-oxoprop-1-en-3-yl, acetylamino and amino groups, respectively. It is an alkaloid isolated from Streptomyces and Salinispora species, exhibits potent immunosuppressive activity, and inhibits Fyn and Lck protein kinases.
1,7,8-trihydroxy-3-methyl-2,3,4,7-tetrahydro-1H-benzo[a]anthracen-12-one [IIN-based on: CCMSLIB00000845261]
[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl] (E)-3-phenylprop-2-enoate [IIN-based on: CCMSLIB00000848381]
[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl] (E)-3-phenylprop-2-enoate [IIN-based: Match]
1,7,8-trihydroxy-3-methyl-2,3,4,7-tetrahydro-1H-benzo[a]anthracen-12-one [IIN-based: Match]
1,7,8-trihydroxy-3-methyl-2,3,4,7-tetrahydro-1H-benzo[a]anthracen-12-one_major
2-Naphthalenepropanol, 6-methoxy-a-methyl-, hydrogen sulfate
3-O-Benzyl-4,5-O-(1-methylethyldiene)-b-D-fructopyranose
(E)-1-O-Cinnamoyl-beta-D-glucose
Moracin C
Moracin C, a natural product, is an anti-inflammatory agent. Moracin C inhibits LPS-activated reactive oxygen species (ROS) and nitric oxide (NO) release from cells[1]. Moracin C, a natural product, is an anti-inflammatory agent. Moracin C inhibits LPS-activated reactive oxygen species (ROS) and nitric oxide (NO) release from cells[1].
(E)-2-O-Cinnamoyl-beta-D-glucopyranose
Hydroxytanshinone
6,11-Dihydroxy-2,2-dimethylpyrano[3,2-c]xanthen-7(2H)-one
1,7,8-Trihydroxy-3-methyl-2,3,4,7-tetrahydro-12(1H)-tetraphenone
3-[[2-[4-(cyanomethyl)phenoxy]acetyl]amino]benzoic acid
(E)-but-2-enedioic acid,2-methyloxirane,oxirane,propane-1,2,3-triol
2,5-di(dodecan-2-yl)benzene-1,4-diol
C20H16F2O (310.11691499999995)
ethyl 2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate
C15H20BClO4 (310.11431000000005)
2-(4-FLUOROPHENYL)-3-METHYLTHIO-4,5-DIHYDRO-2H-BENZO[G]INDAZOLE
TERT-BUTYL 4-(5-FORMYL-4-METHYLTHIAZOL-2-YL)PIPERIDINE-1-CARBOXYLATE
2-(2-Bromo-3,5-dimethylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
1-(anthracen-9-ylmethyl)-3-methyl-1,2-dihydroimidazol-1-ium,chloride
2,6-Bis(4-fluorobenzylidene)cyclohexanone
C20H16F2O (310.11691499999995)
(4-NITRO-[1,1-BIPHENYL]-4-YL)(PIPERIDIN-1-YL)METHANONE
(3-NITRO-[1,1-BIPHENYL]-4-YL)(PIPERIDIN-1-YL)METHANONE
3-CYCLOPENTYL-2-(4-METHANESULFONYL-PHENYL)-PROPIONIC ACID METHYL ESTER
C16H22O4S (310.12387320000005)
3-pyridylamine, n-(1-methylethyl)-2-(1-piperazinyl)-,dihydrochloride monohydrate
C12H24Cl2N4O (310.13270739999996)
1,2-Benzenedicarboperoxoicacid, 1,2-bis(1,1-dimethylethyl) ester
Pyrimido[1,2-a]benzimidazol-4-amine, N-(3,4-difluorophenyl)-2-methyl- (9CI)
2,3,5,6-Tetrafluoro-4-(6-hydroxyhexyloxy)benzoic acid
Butanedioic acid,2-(diethoxyphosphinyl)-, 1,4-diethyl ester
1-ETHYL-3-METHYLIMIDAZOLIUM 2-(2-METHOXYETHOXY)ETHYL SULFATE
2-[2-(4-phenylanilino)-1,3-thiazol-4-yl]acetic acid
2,5-Dihydroxyphenyl(diphenyl)phosphine Oxide
C18H15O3P (310.07587700000005)
trans-4-hydroxy-1-(4-nitrobenzyloxycarbonyl)-l-proline
3-(4-Methoxyphenyl)-2-oxo-4-phenylcyclobutyl acetate
2-(BIPHENYL-4-CARBONYL)-3-OXO-BUTYRICACIDETHYLESTER
N-Benzyl-1-[6-(2,4-difluorophenyl)-2-pyridyl]MethanaMine
C19H16F2N2 (310.12814799999995)
3-(4-butylphenyl)-2-sulfanylidene-1H-quinazolin-4-one
C18H18N2OS (310.11397780000004)
Methyltris(trimethylsiloxy)silane
C10H30O3Si4 (310.12719500000003)
8-BENZYLOXY-2-METHYL-IMIDAZO[1,2-A]PYRIDINE-3-CARBOXYLIC ACID ETHYL ESTER
ETHYL 4-HYDROXY-2-OXO-1-PHENYL-1,2-DIHYDRO-1,8-NAPHTHYRIDINE-3-CARBOXYLATE
4-(Hydroxymethyl)-1,2-O-isopropylidene-3-O-benzyl-a-D-erythro-pentofuranose
4-[(4-hydroxyphenyl)-phenylphosphoryl]phenol
C18H15O3P (310.07587700000005)
1-CYCLOHEXYL-2-(3-FURANYL)-1H-BENZIMIDAZOLE-5-CARBOXYLIC ACID
ethyl 3-[2-ethoxy-1-(3-methylphenyl)-2-oxoethyl]sulfanylpropanoate
C16H22O4S (310.12387320000005)
3-O-Benzyl-4-C-hydroxymethyl-1,2-O-isopropylidene-alpha-D-ribofuranose
Orantinib
C471 - Enzyme Inhibitor > C1404 - Protein Kinase Inhibitor > C1967 - Tyrosine Kinase Inhibitor D004791 - Enzyme Inhibitors > D047428 - Protein Kinase Inhibitors
ethyl 5-amino-1-(4-sulfamoylphenyl)pyrazole-4-carboxylate
C12H14N4O4S (310.07357240000005)
Trepibutone
A - Alimentary tract and metabolism > A03 - Drugs for functional gastrointestinal disorders > A03A - Drugs for functional gastrointestinal disorders C78272 - Agent Affecting Nervous System > C29698 - Antispasmodic Agent
ethyl 3-(2-ethoxy-2-oxo-1-o-tolylethylthio)propanoate
C16H22O4S (310.12387320000005)
ethyl 3-(2-ethoxy-2-oxo-1-p-tolylethylthio)propanoate
C16H22O4S (310.12387320000005)
Benzo[a]phenoxazin-7-ium,9-(dimethylamino)-, chloride (1:1)
5-(6-Hydroxybenzofuran-2-yl)-2-(3-methylbut-1-enyl)benzene-1,3-diol
9-(BENZYLOXY)-3-(2-HYDROXYETHYL)-2-METHYL-4H-PYRIDO[1,2-A]PYRIMIDIN-4-ONE
8-DIMETHYLAMINO-2,3-BENZOPHENOXAZINE HEMI(ZINC CHLORIDE) SALT
Phosphoric acidmono-N-dodecyl estersodium salt
C12H25Na2O4P (310.12857800000006)
Talabostat mesylate
C10H23BN2O6S (310.13698080000006)
C471 - Enzyme Inhibitor > C783 - Protease Inhibitor
2-(4-(ISOPROPYLSULFONYL)PHENYL)-4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLANE
2-(Dibenzo[b,d]thiophen-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
5-(4-METHYLSULFANYL-PHENYL)-1-PHENYL-1H-PYRAZOLE-3-CARBOXYLIC ACID
7-[3-(chlorodimethylsilyl)propoxy-4-methylcoumarin
C15H19ClO3Si (310.07919339999995)
2-(4-Methoxybenzyloxycarbonyloxyimino)-2-Phenylacetonitrile
Methyl 4-methoxy-2-(trifluoromethyl)-[1,1-biphenyl]-4-carboxylate
Diethyl(methyl)propylammonium Bis(fluorosulfonyl)imide
10-Chloro-11-(4-piperidinylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine
7-Chloro-11-(4-piperidinylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine
beta-(4,4-Difluoro-1-piperidinyl)-2-(trifluoromethyl)-5-pyrimidineethanamine
C12H15F5N4 (310.12168099999997)
1-(2-BENZO[1,3]DIOXOL-5-YL-IMIDAZO[1,2-A]PYRIMIDIN-3-YLMETHYL)-PIPERIDINE-4-CARBOXYLICACID
4-[CARBOXY-(4-METHOXY-PHENYL)-METHYL]-PIPERAZINE-1-CARBOXYLICACIDTERT-BUTYLESTERHYDROCHLORIDE
Butanedioic acid,2-(diphenylmethylene)-, 1-ethyl ester
2-(2-(2-Bromoethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
1-Amino-4-methylamino-9,10-dioxo-9,10-dihydroanthracene-2-carboxylicacidmethylester
5-(1-Piperazinyl)-2-benzofurancarboxylic acid ethyl ester hydrochloride
1-(Diphenylmethyl)-3-azetidinamine dihydrochloride
5-Methyl-5-(4-phenoxy-phenyl)-pyrimidine-2,4,6-trione
1,7-Bis(4-hydroxyphenyl)-3-hydroxy-1,3-heptadien-5-one
isotanshinone iib
A diterpenoid that is 1,2,3,4-tetrahydrophenanthro[3,2-b]furan-7,11-dione substituted by a hydroxymethyl group at position 4 and methyl groups at positions 4 and 8 respectively. Isolated from Salvia miltiorrhiza, it exhibits platelet aggregation inhibitory activity.
N-[2-furanyl-(8-hydroxy-7-quinolinyl)methyl]-2-methylpropanamide
8-methylene-7-(phenylmethyl)-5H-[1,3]dioxolo[4,5-g]quinazoline-6-thione
N-{8-amino-4-[(2E)-3-methoxyprop-2-enoyl]pyrrolo[4,3,2-de]quinolin-6-yl}acetamide
[(8-methyl-2-oxo-4-phenyl-2H-chromen-7-yl)oxy]acetic acid
4-methyl-N-[1-methyl-2-oxo-6-(trifluoromethyl)-3-pyridinyl]benzamide
8-methoxy-N-(6-methylpyridin-2-yl)-2-oxo-2H-chromene-3-carboxamide
6-Methoxy-4-methyl-2-[(2-methylphenyl)methylthio]quinazoline
C18H18N2OS (310.11397780000004)
4-Hydroxy-3-nitrophenylacetyl-epsilon-aminocaproic acid
2-(methylthio)-6-phenyl-6,7-dihydro-5H-[1,2,4]triazolo[5,1-b]quinazolin-8-one
1,2-Benzenedicarboxylic acid, bis(trimethylsilyl) ester
2,2,5,5-Tetramethyl-3,4-diphenyl-2,5-dihydro-1,2,5-oxadisilole
5-[(2-Aminoethyl)amino]-6-fluoro-3-(1H-pyrrol-2-YL)benzo[CD]indol-2(1H)-one
C17H15FN4O (310.12298319999996)
(5s)-2-{[(1s)-1-(4-Fluorophenyl)ethyl]amino}-5-(1-Hydroxy-1-Methylethyl)-5-Methyl-1,3-Thiazol-4(5h)-One
1,3,4-Trihydroxy-5-(3-phenoxypropyl)-cyclohexane-1-carboxylic A cid
4-hydroxy-7-methoxy-3-[(1S)-1-phenylpropyl]chromen-2-one
4-hydroxy-3-[(1S)-3-hydroxy-1-phenylbutyl]chromen-2-one
[4-[5-(3-Chloroanilino)pyridin-3-yl]phenyl]methanol
(2S)-5-amino-5-oxo-2-[[(2R,3R,4R,5R)-2,3,4,5,6-pentahydroxyhexyl]amino]pentanoic acid
5-(Aminoiminomethyl)amino-5-deoxyadenosine
C10H16N9O3+ (310.13760460000003)
Biolf 143
C12H18N6O4 (310.13894680000004)
D000890 - Anti-Infective Agents > D000998 - Antiviral Agents
4-Amino-5-(2-amino-3-phenylpropanoyl)peroxy-5-oxopentanoic acid
Microdiplodiasol
A member of the class of xanthones that is 1,2,3,4,4a,9a-hexahydro-9H-xanthen-9-one substituted by hydroxy groups at positions 1, 4, 8 and 9a, a hydroxymethyl group at position 6 and a methyl group at position 4a. Isolated from the endophytic fungus Microdiplodia species, it exhibits antibacterial activity.
3-[[(3-Methoxyphenyl)-oxomethyl]amino]-2-benzofurancarboxamide
2-O-(alpha-L-rhamnopyranosyl)-alpha-L-rhamnopyranose
2-(2-oxo-1-benzo[cd]indolyl)-N-(2-oxolanylmethyl)acetamide
6-methoxy-2-oxo-N-(3-pyridinylmethyl)-1-benzopyran-3-carboxamide
2-[[1-(4-Chlorophenyl)-2,5-dioxo-3-pyrrolidinyl]-methylamino]acetic acid methyl ester
3-O-(alpha-D-rhamnopyranosyl)-alpha-D-rhamnopyranose
4-methoxy-2-[3-(4-methoxyphenyl)-5-methyl-1H-pyrazol-4-yl]phenol
N-(furan-2-ylmethyl)-4-(2-methylimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-amine
(5Z)-2-benzylimino-5-[(4-hydroxyphenyl)methylidene]-1,3-thiazolidin-4-one
4-[4-(Phenylmethyl)-1-piperazinyl]thieno[2,3-d]pyrimidine
C17H18N4S (310.12521080000005)
4-[[2-(1-Benzotriazolyl)-1-oxoethyl]amino]benzoic acid methyl ester
3-[[2-(1-Benzotriazolyl)-1-oxoethyl]amino]benzoic acid methyl ester
4-(1,3-dioxo-2-isoindolyl)-N-(2-hydroxyethyl)benzamide
2-furancarboxylic acid (7-methyl-4-oxo-2,3-dihydro-1H-cyclopenta[c][1]benzopyran-9-yl) ester
N-(3-cyano-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophen-2-yl)-3-methylbenzamide
C18H18N2OS (310.11397780000004)
(3s)-3-(4-Methoxybenzyl)-4-Methyl-3,4-Dihydro-1h-1,4-Benzodiazepine-2,5-Dione
2,7-Diamino-3-[(2-fluorophenyl)diazenyl]-5-methylpyrazolo[1,5-a]pyrimidine-6-carbonitrile
3,4-dihydro-1H-isoquinolin-2-yl-(4-ethyl-5-thieno[3,2-b]pyrrolyl)methanone
C18H18N2OS (310.11397780000004)
N-cyclopentyl-3-[(4-methylphenyl)sulfonylamino]propanamide
N-[[1H-benzimidazol-2-yl(oxo)methyl]amino]carbamic acid (phenylmethyl) ester
5-[(Carbamimidoylthio)methyl]-2-(3-methylbutoxy)benzoic acid methyl ester
N-hydroxy-1-[(4-methoxyphenyl)methyl]-5-methylindole-6-carboxamide
(2R,3R,4S)-1-(2-fluorobenzoyl)-4-(hydroxymethyl)-3-phenylazetidine-2-carbonitrile
C18H15FN2O2 (310.11175019999996)
(2S,3R,4R)-1-[(2-fluorophenyl)-oxomethyl]-4-(hydroxymethyl)-3-phenyl-2-azetidinecarbonitrile
C18H15FN2O2 (310.11175019999996)
(2R,3S,4S)-1-[(2-fluorophenyl)-oxomethyl]-4-(hydroxymethyl)-3-phenyl-2-azetidinecarbonitrile
C18H15FN2O2 (310.11175019999996)
3-(4-Tert-butylanilino)-2-(thiophene-3-carbonyl)prop-2-enenitrile
C18H18N2OS (310.11397780000004)
(2S,3R,4S)-1-[(2-fluorophenyl)-oxomethyl]-4-(hydroxymethyl)-3-phenyl-2-azetidinecarbonitrile
C18H15FN2O2 (310.11175019999996)
(2S,3S,4R)-1-[(2-fluorophenyl)-oxomethyl]-4-(hydroxymethyl)-3-phenyl-2-azetidinecarbonitrile
C18H15FN2O2 (310.11175019999996)
(2S,3S,4S)-1-[(2-fluorophenyl)-oxomethyl]-4-(hydroxymethyl)-3-phenyl-2-azetidinecarbonitrile
C18H15FN2O2 (310.11175019999996)
(2R,3R,4R)-1-[(2-fluorophenyl)-oxomethyl]-4-(hydroxymethyl)-3-phenyl-2-azetidinecarbonitrile
C18H15FN2O2 (310.11175019999996)
(2R,3S,4R)-1-[(2-fluorophenyl)-oxomethyl]-4-(hydroxymethyl)-3-phenyl-2-azetidinecarbonitrile
C18H15FN2O2 (310.11175019999996)
N-[(10-methyl-9,10-dihydroacridin-9-yl)carbonyl]-beta-alanine
N-butyl-N(2)-[(R)-2-hydroxy-2-phenylacetyl]-L-cysteinamide
1-methyl-4-(10-oxo-9,10-dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thiophen-4-ylidene)piperidinium
C19H20NOS+ (310.12655300000006)
6-(2-Carboxy-3-hydroxy-2-methylpropoxy)-3,4,5-trihydroxyoxane-2-carboxylic acid
(E)-N-ethyl-3-(furan-2-yl)-2-[[(E)-3-phenylprop-2-enoyl]amino]prop-2-enamide
3,4,5-Trihydroxy-6-[3-hydroxy-2-(hydroxymethyl)-2-methylpropanoyl]oxyoxane-2-carboxylic acid
N-Acetyl-4-(3-methoxyacryloyl)pyrrolo[4,3,2-de]quinoline-6,8-diamine
1-Acetyl-3-(4-nitrophenyl)-4-(pyridin-2-yl)-2-pyrazoline
1-Acetyl-4-(4-nitrophenyl)-3-(pyridin-2-yl)-2-pyrazoline
Pikrotin
Picrotin is an organic heteropentacyclic compound that is picrotoxinin in which the olefinic double bond has undergone addition of water to give the corresponding tertiary alcohol. It is the less toxic component of picrotoxin, lacking GABA activity. It has a role as a plant metabolite. It is an organic heteropentacyclic compound, an epoxide, a tertiary alcohol, a gamma-lactone, a diol and a picrotoxane sesquiterpenoid. It is functionally related to a picrotoxinin. Picrotin is a natural product found in Dendrobium moniliforme and Anamirta cocculus with data available. An organic heteropentacyclic compound that is picrotoxinin in which the olefinic double bond has undergone addition of water to give the corresponding tertiary alcohol. It is the less toxic component of picrotoxin, lacking GABA activity. C78272 - Agent Affecting Nervous System > C47795 - CNS Stimulant Picrotin is an active compound, also is one of the composition of picrotoxin (an antagonist of GABAA receptors (GABAARs) and glycine receptors (GlyRs)). Picrotin has sensitivity for GlyRs/b> with IC50 values range from 5.2 μM to 106 μM. Picrotin can be used for the research of neurotransmission[1][2]. Picrotin is an active compound, also is one of the composition of picrotoxin (an antagonist of GABAA receptors (GABAARs) and glycine receptors (GlyRs)). Picrotin has sensitivity for GlyRs/b> with IC50 values range from 5.2 μM to 106 μM. Picrotin can be used for the research of neurotransmission[1][2]. Picrotin is an active compound, also is one of the composition of picrotoxin (an antagonist of GABAA receptors (GABAARs) and glycine receptors (GlyRs)). Picrotin has sensitivity for GlyRs/b> with IC50 values range from 5.2 μM to 106 μM. Picrotin can be used for the research of neurotransmission[1][2].
SULFADOXINE
C12H14N4O4S (310.07357240000005)
D000890 - Anti-Infective Agents > D000977 - Antiparasitic Agents > D000981 - Antiprotozoal Agents C254 - Anti-Infective Agent > C276 - Antiparasitic Agent > C277 - Antiprotozoal Agent D000890 - Anti-Infective Agents > D013424 - Sulfanilamides
TSU-68 (SU6668, Orantinib)
D004791 - Enzyme Inhibitors > D047428 - Protein Kinase Inhibitors
[3,4,5-Trihydroxy-6-(hydroxymethyl)oxan-2-yl] 3-phenylprop-2-enoate
phenguignardic acid
A member of the class of dioxolanes that is 1,3-dioxolane substituted by a carboxy, benzyl and benzylidene groups at positions 2, 2 and 4, respectively. It is a phytotoxic metabolite of the grape black rot fungus Guignardia bidwellii.
GK187
C14H15F5O2 (310.09921499999996)
GK187 is a potent and selective Group VIA calcium-independent phospholipase A2 (GVIA iPLA2) inhibitor with an XI(50) value of 0.0001. GK187 can be used for researching various neurological disorders[1]. [The XI(50) is the mole fraction of the inhibitor in the total substrate interface required to inhibit the enzyme by 50\%.]
ML254
C18H15FN2O2 (310.11175019999996)
ML254 is a potent mGlu5 potentiator, with EC50 and pEC50 of 9.3 nM and 8.03 nM for rat mGlu5, respectively. ML254 can be used for researching schizophrenia[1]. ML254 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.