Mabuterol (BioDeep_00000271154)
代谢物信息卡片
Mabuterol
化学式: C13H18ClF3N2O (310.1059684)
中文名称: 马布台诺
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC(C)(C)NCC(C1=CC(=C(C(=C1)Cl)N)C(F)(F)F)O
InChI: InChI=1S/C13H18ClF3N2O/c1-12(2,3)19-6-10(20)7-4-8(13(15,16)17)11(18)9(14)5-7/h4-5,10,19-20H,6,18H2,1-3H3
描述信息
D019141 - Respiratory System Agents > D018927 - Anti-Asthmatic Agents > D001993 - Bronchodilator Agents
C78272 - Agent Affecting Nervous System > C29747 - Adrenergic Agent > C87053 - Adrenergic Agonist
D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents > D000322 - Adrenergic Agonists
D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents
CONFIDENCE standard compound; INTERNAL_ID 1102
同义名列表
1 个代谢物同义名
数据库引用编号
8 个数据库交叉引用编号
- ChEBI: CHEBI:135325
- PubChem: 3995
- ChEMBL: CHEMBL86749
- CAS: 56341-08-3
- MoNA: AU110205
- MoNA: AU110204
- MoNA: AU110201
- PMhub: MS000001682
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Andrew K Evans, Heui Hye Park, Nay Lui Saw, Kratika Singhal, Gaku Ogawa, Ryan D Leib, Mehrdad Shamloo. Age-related neuroinflammation and pathology in the locus coeruleus and hippocampus: beta-adrenergic antagonists exacerbate impairment of learning and memory in aged mice.
Neurobiology of aging.
2021 10; 106(?):241-256. doi:
10.1016/j.neurobiolaging.2021.06.012. [PMID: 34320462] - Murat Faruk Us, Usama Alshana, Ibrahim Lubbad, Nilgün G Göğer, Nusret Ertaş. Dispersive liquid-liquid microextraction based on solidification of floating organic drop combined with field-amplified sample injection in capillary electrophoresis for the determination of beta(2)-agonists in bovine urine.
Electrophoresis.
2013 Mar; 34(6):854-61. doi:
10.1002/elps.201200348. [PMID: 23335131] - Xiang-Dang Du, Yin-Liang Wu, Hong-Ju Yang, Ting Yang. Simultaneous determination of 10 β2-agonists in swine urine using liquid chromatography-tandem mass spectrometry and multi-walled carbon nanotubes as a reversed dispersive solid phase extraction sorbent.
Journal of chromatography. A.
2012 Oct; 1260(?):25-32. doi:
10.1016/j.chroma.2012.08.066. [PMID: 22959774] - T Bernsmann, P Fürst, M Godula. Quick screening of priority β-agonists in urine using automated TurboFlow™-LC/Exactive mass spectrometry.
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment.
2011 Oct; 28(10):1352-63. doi:
10.1080/19440049.2011.619504. [PMID: 22007889] - P Garcia, A-C Paris, J Gil, M-A Popot, Y Bonnaire. Analysis of β-agonists by HPLC/ESI-MS(n) in horse doping control.
Biomedical chromatography : BMC.
2011 Jan; 25(1-2):147-54. doi:
10.1002/bmc.1562. [PMID: 21204111] - Jianrong Nie, Mingli Zhu, Jin Lian, Yunshan Pan, Xianglian Deng, Cuiping Hu. [Determination of fifteen beta-agonists in animal urine by high performance liquid chromatography-tandem mass spectrometry].
Se pu = Chinese journal of chromatography.
2010 Aug; 28(8):759-64. doi:
10.3724/sp.j.1123.2010.00759. [PMID: 21261043] - R J B Peters, J E Oosterink, A A M Stolker, C Georgakopoulos, M W F Nielen. Generic sample preparation combined with high-resolution liquid chromatography-time-of-flight mass spectrometry for unification of urine screening in doping-control laboratories.
Analytical and bioanalytical chemistry.
2010 Apr; 396(7):2583-98. doi:
10.1007/s00216-010-3484-3. [PMID: 20155493] - Francisco Moragues, Carmen Igualada. How to decrease ion suppression in a multiresidue determination of beta-agonists in animal liver and urine by liquid chromatography-mass spectrometry with ion-trap detector.
Analytica chimica acta.
2009 Apr; 637(1-2):193-5. doi:
10.1016/j.aca.2008.10.065. [PMID: 19286029] - Ting Xu, Bao M Wang, Wei Sheng, Qing X Li, Xiao L Shao, Ji Li. Application of an enzyme-linked immunosorbent assay for the detection of clenbuterol residues in swine urine and feeds.
Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes.
2007 Feb; 42(2):173-7. doi:
10.1080/03601230601123508. [PMID: 17365332] - Xiumei Lu, Pei Liu, Huashan Chen, Feng Qin, Famei Li. Enantioselective pharmacokinetics of mabuterol in rats studied using sequential achiral and chiral HPLC.
Biomedical chromatography : BMC.
2005 Nov; 19(9):703-8. doi:
10.1002/bmc.584. [PMID: 16206140] - Leslie C Dickson, James D MacNeil, Stephen Lee, Adrian C E Fesser. Determination of beta-agonist residues in bovine urine using liquid chromatography-tandem mass spectrometry.
Journal of AOAC International.
2005 Jan; 88(1):46-56. doi:
. [PMID: 15759725] - G Brambilla, M Fiori, B Rizzo, V Crescenzi, G Masci. Use of molecularly imprinted polymers in the solid-phase extraction of clenbuterol from animal feeds and biological matrices.
Journal of chromatography. B, Biomedical sciences and applications.
2001 Aug; 759(1):27-32. doi:
10.1016/s0378-4347(01)00199-2. [PMID: 11499626] - K Hamada, T Kihana, M Kataoka, S Yoshioka, S Nishio, S Matsuura, M Ito. Urinary disturbance after therapy for cervical cancer: urodynamic evaluation and beta2-agonist medication.
International urogynecology journal and pelvic floor dysfunction.
1999; 10(6):365-70. doi:
10.1007/s001920050061. [PMID: 10614971] - F Ramos, C Santos, A Silva, M I da Silveira. Beta2-adrenergic agonist residues: simultaneous methyl- and butylboronic derivatization for confirmatory analysis by gas chromatography-mass spectrometry.
Journal of chromatography. B, Biomedical sciences and applications.
1998 Sep; 716(1-2):366-70. doi:
10.1016/s0378-4347(98)00292-8. [PMID: 9824253] - M J Groot, R Schilt, J S Ossenkoppele, P L Berende, W Haasnoot. Combinations of growth promoters in veal calves: consequences for screening and confirmation methods.
Zentralblatt fur Veterinarmedizin. Reihe A.
1998 Sep; 45(6-7):425-40. doi:
10.1111/j.1439-0442.1998.tb00845.x. [PMID: 9793473] - G Van Vyncht, S Preece, P Gaspar, G Maghuin-Rogister, E DePauw. Gas and liquid chromatography coupled to tandem mass spectrometry for the multiresidue analysis of beta-agonists in biological matrices.
Journal of chromatography. A.
1996 Oct; 750(1-2):43-9. doi:
10.1016/0021-9673(96)00540-7. [PMID: 8938381] - S Collins, M O'Keeffe, M R Smyth. Multi-residue analysis for beta-agonists in urine and liver samples using mixed phase columns with determination by radioimmunoassay.
The Analyst.
1994 Dec; 119(12):2671-4. doi:
10.1039/an9941902671. [PMID: 7879873] - J Kim, S Shigetomi, K Tanaka, Z O Yamada, S Hashimoto, S Fukuchi. [The role of beta 2-adrenoceptor on the pathogenesis of insulin resistance in essential hypertension].
Nihon Naibunpi Gakkai zasshi.
1994 Jun; 70(5):521-8. doi:
10.1507/endocrine1927.70.5_521. [PMID: 7958101] - H Kai, A Ishibashi, K Takahama, K Sakata, Y Isohama, M Nakayama, A Sugii, T Miyata. [Method for evaluating pulmonary clearance in mice and its pharmacological applications].
Nihon Kyobu Shikkan Gakkai zasshi.
1993 Jun; 31(6):679-85. doi:
NULL. [PMID: 8102188] - G A Qureshi, A Eriksson. Determination of clenbuterol and mabuterol in equine plasma by ion-pair liquid chromatography with electrochemical detection. Chromatographic and electrochemical characteristics.
Journal of chromatography.
1988 May; 441(1):197-205. doi:
10.1016/s0021-9673(01)84666-5. [PMID: 2900250] - I Yamamoto, E Matsuura, M Horiba, K Akima, K Nomura, T Aizawa. Enzyme immunoassay for mabuterol, a selective beta 2-adrenergic stimulant in the trachea.
Journal of immunoassay.
1985; 6(3):261-76. doi:
10.1080/01971528508063033. [PMID: 3900139] - T W Guentert, J N Buskin, R L Galeazzi. Single dose pharmacokinetics of mabuterol in man.
Arzneimittel-Forschung.
1984; 34(11A):1691-6. doi:
NULL. [PMID: 6152164] - E Osada, S Sakaya, K Sanai, K Seri. Pharmacological studies of mabuterol, a new selective beta 2-stimulant. III: Effects on the central nervous system, striated muscle and carbohydrate and lipid metabolism.
Arzneimittel-Forschung.
1984; 34(11A):1652-8. doi:
NULL. [PMID: 6152158] - T Yuge, T Hase, Y Takayanagi, T Kamasuka, K Amemiya, M Horiba. Pharmacokinetic studies of mabuterol, a new selective beta 2-stimulant. I: Studies on the absorption, distribution and excretion in rats.
Arzneimittel-Forschung.
1984; 34(11A):1659-67. doi:
NULL. [PMID: 6152159] - M Horiba, T Murai, K Nomura, T Yuge, K Sanai, E Osada. Pharmacokinetic studies of mabuterol, a new selective beta 2-stimulant. II: Urinary metabolites of mabuterol in rats and their pharmacological effects.
Arzneimittel-Forschung.
1984; 34(11A):1668-79. doi:
NULL. [PMID: 6152160]