N-[1-(Aminocarbonyl)-4-[(2-chloro-1-iminoethyl)amino]butyl]-benzamide (BioDeep_00000389870)
代谢物信息卡片
化学式: C14H19ClN4O2 (310.11964639999997)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1=CC=C(C=C1)C(=O)NC(CCCN=C(CCl)N)C(=O)N
InChI: InChI=1S/C14H19ClN4O2/c15-9-12(16)18-8-4-7-11(13(17)20)19-14(21)10-5-2-1-3-6-10/h1-3,5-6,11H,4,7-9H2,(H2,16,18)(H2,17,20)(H,19,21)
相关代谢途径
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代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
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Plant Reactome(0)
INOH(0)
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0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Yiming Shen, Qi You, Yiling Wu, Jie Wu. Inhibition of PAD4-mediated NET formation by cl-amidine prevents diabetes development in nonobese diabetic mice.
European journal of pharmacology.
2022 Feb; 916(?):174623. doi:
10.1016/j.ejphar.2021.174623. [PMID: 34767782] - Ali Z Siddiqui, Umar F Bhatti, Qiufang Deng, Ben E Biesterveld, Yuzi Tian, Zhenyu Wu, Julia Dahl, Baoling Liu, Jie Xu, Yui Koike, Jun Song, Jifeng Zhang, Yongqing Li, Hasan B Alam, Aaron M Williams. Cl-Amidine Improves Survival and Attenuates Kidney Injury in a Rabbit Model of Endotoxic Shock.
Surgical infections.
2021 May; 22(4):421-426. doi:
10.1089/sur.2020.189. [PMID: 32833601] - Martin Maronek, Barbora Gromova, Robert Liptak, Barbora Konecna, Michal Pastorek, Barbora Cechova, Maria Harsanyova, Jaroslav Budis, David Smolak, Jan Radvanszky, Tomas Szemes, Jana Harsanyiova, Alzbeta Kralova Trancikova, Roman Gardlik. Extracellular DNA Correlates with Intestinal Inflammation in Chemically Induced Colitis in Mice.
Cells.
2021 01; 10(1):. doi:
10.3390/cells10010081. [PMID: 33418977] - Virginia M Vargas-Muñoz, Arisai Martínez-Martínez, Enriqueta Muñoz-Islas, Martha B Ramírez-Rosas, Rosa I Acosta-González, Juan M Jiménez-Andrade. Chronic administration of Cl-amidine, a pan-peptidylarginine deiminase inhibitor, does not reverse bone loss in two different murine models of osteoporosis.
Drug development research.
2020 02; 81(1):93-101. doi:
10.1002/ddr.21608. [PMID: 31633211] - Hoshimi Kawaguchi, Isao Matsumoto, Atsumu Osada, Izumi Kurata, Hiroshi Ebe, Yuki Tanaka, Asuka Inoue, Naoto Umeda, Yuya Kondo, Hiroto Tsuboi, Akihito Ishigami, Takayuki Sumida. Peptidyl arginine deiminase inhibition suppresses arthritis via decreased protein citrullination in joints and serum with the downregulation of interleukin-6.
Modern rheumatology.
2019 Nov; 29(6):964-969. doi:
10.1080/14397595.2018.1532545. [PMID: 30285515] - Kiyomi Mizugishi, Kouhei Yamashita. Neutrophil extracellular traps are critical for pregnancy loss in sphingosine kinase-deficient mice on 129Sv/C57BL/6 background.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
2017 12; 31(12):5577-5591. doi:
10.1096/fj.201700399rr. [PMID: 28842426]