Emycin E (BioDeep_00000292709)
代谢物信息卡片
Emycin E
化学式: C19H18O4 (310.1205028)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC1CC(=O)c2c(ccc(O)c2C2OCc3c(O)cccc32)C1
InChI: InChI=1S/C19H18O4/c1-10-7-11-5-6-15(21)18(17(11)16(22)8-10)19-12-3-2-4-14(20)13(12)9-23-19/h2-6,10,19-21H,7-9H2,1H3
描述信息
D004791 - Enzyme Inhibitors > D011500 - Protein Synthesis Inhibitors
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents
D005765 - Gastrointestinal Agents
同义名列表
1 个代谢物同义名
相关代谢途径
Reactome(0)
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代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Romain Métivier, Isabelle Bourven, Jérome Labanowski, Gilles Guibaud. Interaction of erythromycin ethylsuccinate and acetaminophen with protein fraction of extracellular polymeric substances (EPS) from various bacterial aggregates.
Environmental science and pollution research international.
2013 Oct; 20(10):7275-85. doi:
10.1007/s11356-013-1738-2. [PMID: 23649599] - Y A Cho, W Lee, J S Choi. Effects of curcumin on the pharmacokinetics of tamoxifen and its active metabolite, 4-hydroxytamoxifen, in rats: possible role of CYP3A4 and P-glycoprotein inhibition by curcumin.
Die Pharmazie.
2012 Feb; 67(2):124-30. doi:
NULL. [PMID: 22512082] - Yan-Ming Liu, Yan-Mei Shi, Zhuan-Li Liu, Long-Fei Peng. Sensitive determination of tilmicosin, erythromycin ethylsuccinate and clindamycin by CE with electrochemiluminescence detection using azithromycin as internal standard and its applications.
Journal of separation science.
2010 May; 33(9):1305-11. doi:
10.1002/jssc.200900843. [PMID: 20235137] - G A Albarellos, V E Kreil, L A Ambros, S Waxman, L Montoya, L Tarragona, P C Quaine, R E Hallu, M Rebuelto. Pharmacokinetics of erythromycin after the administration of intravenous and various oral dosage forms to dogs.
Journal of veterinary pharmacology and therapeutics.
2008 Dec; 31(6):496-500. doi:
10.1111/j.1365-2885.2008.00982.x. [PMID: 19000270] - Nawal El-Rabbat, Hassan F Askal, Pakinaz Y Khashaba, Noha N Attia. A validated spectrofluorometric assay for the determination of certain macrolide antibiotics in pharmaceutical formulations and spiked biological fluids.
Journal of AOAC International.
2006 Sep; 89(5):1276-87. doi:
. [PMID: 17042176] - Yi Gu, Guangji Wang, Jianguo Sun. Simultaneous determination of erythromycin ethylsuccinate and its metabolite erythromycin in human plasma using liquid chromatography-electrospray ionization mass spectrometry for clinical study.
Journal of pharmaceutical and biomedical analysis.
2006 Feb; 40(3):737-43. doi:
10.1016/j.jpba.2005.11.005. [PMID: 16376051] - Jeffrey Lakritz, W David Wilson, Antoinette E Marsh, Judy E Mihalyi. Pharmacokinetics of erythromycin ethylsuccinate after intragastric administration to healthy foals.
Veterinary therapeutics : research in applied veterinary medicine.
2002; 3(2):189-95. doi:
NULL. [PMID: 19750750] - F Delatour, D Le Guludec, F Caron, F Faurisson, J C Torlotin, B Rouveix. Effect of a single oral dose of two erythromycin ethylsuccinate formulations on gastric emptying in healthy volunteers: a scintigraphic study.
Fundamental & clinical pharmacology.
1998; 12(3):292-7. doi:
10.1111/j.1472-8206.1998.tb00957.x. [PMID: 9646062] - R M Rolland, L V Chalifoux, S S Snook, L M Ausman, L D Johnson. Five spontaneous deaths associated with Clostridium difficile in a colony of cotton-top tamarins (Saguinus oedipus).
Laboratory animal science.
1997 Oct; 47(5):472-6. doi:
NULL. [PMID: 9355088] - A Gustafsson, V Båverud, A Gunnarsson, M H Rantzien, A Lindholm, A Franklin. The association of erythromycin ethylsuccinate with acute colitis in horses in Sweden.
Equine veterinary journal.
1997 Jul; 29(4):314-8. doi:
10.1111/j.2042-3306.1997.tb03129.x. [PMID: 15338913] - F Caron, M Bouaniche, F Delatour, P Ducrotte, J C Torlotin, P Denis, G Humbert, B Rouveix. Effects of two oral erythromycin ethylsuccinate formulations on the motility of the small intestine in human beings.
Antimicrobial agents and chemotherapy.
1996 Aug; 40(8):1796-800. doi:
10.1128/aac.40.8.1796. [PMID: 8843283] - B Ueberschaer, K Ewe, U Alles, I Schmidtmann. Effect of 4 x 250 mg erythromycin on human gastrointestinal transit.
Zeitschrift fur Gastroenterologie.
1995 Jul; 33(6):340-4. doi:
NULL. [PMID: 7668024] - H Potthast, B Schug, M Elze, R Schwerdtle, H Blume. [Comparison of the bioavailabilities of erythromycin estolate and erythromycin ethylsuccinate dry suspension preparations in steady state].
Die Pharmazie.
1995 Jan; 50(1):56-60. doi:
. [PMID: 7886126] - P S Kokkonen, W M Niessen, U R Tjaden, J van der Greef. Bioanalysis of erythromycin 2'-ethylsuccinate in plasma using phase-system switching continuous-flow fast atom bombardment liquid chromatography-mass spectrometry.
Journal of chromatography.
1991 Apr; 565(1-2):265-75. doi:
10.1016/0378-4347(91)80389-t. [PMID: 1874872] - M I Morasso, J Chávez, M N Gai, A Arancibia. Influence of alcohol consumption on erythromycin ethylsuccinate kinetics.
International journal of clinical pharmacology, therapy, and toxicology.
1990 Oct; 28(10):426-9. doi:
NULL. [PMID: 2258252] - I A Vereshchagin, O D Zhuravleva. [Value of determining the spectrum of blood serum fatty acids in evaluating increasing the effectiveness of antibiotic therapy of dysentery in children with prodigiozan and ephedrine].
Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic].
1989 Mar; 34(3):218-23. doi:
NULL. [PMID: 2502081] - D Bérubé, D Kirouac, D Croteau, M G Bergeron, M Lebel. Plasma bactericidal activity after administration of erythromycin estolate and erythromycin ethylsuccinate to healthy volunteers.
Antimicrobial agents and chemotherapy.
1988 Aug; 32(8):1227-30. doi:
10.1128/aac.32.8.1227. [PMID: 3142349] - D Croteau, M G Bergeron, M LeBel. Pharmacokinetic advantages of erythromycin estolate over ethylsuccinate as determined by high-pressure liquid chromatography.
Antimicrobial agents and chemotherapy.
1988 Apr; 32(4):561-5. doi:
10.1128/aac.32.4.561. [PMID: 3259856] - I Sandström, I Kallings, B Melen. Neonatal chlamydial conjunctivitis. A long term follow-up study.
Acta paediatrica Scandinavica.
1988 Mar; 77(2):207-13. doi:
10.1111/j.1651-2227.1988.tb10631.x. [PMID: 3258462] - I Sandström, O Ringertz. Levels of erythromycin in tear fluid and serum in infants with conjunctivitis.
Scandinavian journal of infectious diseases.
1988; 20(4):429-33. doi:
10.3109/00365548809032481. [PMID: 3264085] - P Ottoila, J Taskinen. Quantitative determination of erythromycin 2'-ethylsuccinate in human plasma by fast atom bombardment mass spectrometry.
Biomedical & environmental mass spectrometry.
1987 Nov; 14(11):659-62. doi:
10.1002/bms.1200141116. [PMID: 2962674] - D Croteau, F Vallée, M G Bergeron, M LeBel. High-performance liquid chromatographic assay of erythromycin and its esters using electrochemical detection.
Journal of chromatography.
1987 Aug; 419(?):205-12. doi:
10.1016/0378-4347(87)80278-5. [PMID: 3499443] - A Kanfer, G Stamatakis, J C Torlotin, G Fredj, S Kenouch, J P Méry. Changes in erythromycin pharmacokinetics induced by renal failure.
Clinical nephrology.
1987 Mar; 27(3):147-50. doi:
NULL. [PMID: 3494560] - L Vaillant, G Lorette, J Loulergue, A Audurier. Erythromycin ethyl succinate: diffusion through interstitial dermal fluid.
European journal of clinical pharmacology.
1987; 33(5):529-30. doi:
10.1007/bf00544250. [PMID: 3501376] - E Salazar-Lindo, R B Sack, E Chea-Woo, B A Kay, Z A Piscoya, R Leon-Barua, A Yi. Early treatment with erythromycin of Campylobacter jejuni-associated dysentery in children.
The Journal of pediatrics.
1986 Aug; 109(2):355-60. doi:
10.1016/s0022-3476(86)80404-8. [PMID: 3488385] - M J Butel, Y Boussougant. [Effect of erythromycin on the fecal flora of infants less than 1-year old].
Pathologie-biologie.
1986 Jun; 34(5 Pt 2):591-5. doi:
NULL. [PMID: 3534749] - E M Gavrilov, S K Zhaugasheva, L V Shchepetkina. [Monomycin distribution in the tissues of animals of various ages].
Farmakologiia i toksikologiia.
1986 Jan; 49(1):69-71. doi:
NULL. [PMID: 3081365] - N M Israfilova, L T Dzhafarova, L T Tarkhanova, R G Ali-zade, G G Alekperova. [Monomycin-induced nephropathy in children].
Pediatriia.
1986 Jan; ?(1):56-7. doi:
NULL. [PMID: 3081872] - R M Victorino, V A Maria. Modifications of the lymphocyte transformation test in a case of drug-induced cholestatic hepatitis.
Diagnostic immunology.
1985; 3(4):177-81. doi:
. [PMID: 2935353] - G J Yakatan, C E Rasmussen, P J Feis, S Wallen. Bioinequivalence of erythromycin ethylsuccinate and enteric-coated erythromycin pellets following multiple oral doses.
Journal of clinical pharmacology.
1985 Jan; 25(1):36-42. doi:
10.1002/j.1552-4604.1985.tb02798.x. [PMID: 3871797] - D C Shanson, P Tidbury, W R McNabb, M Tadayon. The pharmacokinetics and tolerance of oral erythromycin stearate compared with erythromycin ethylsuccinate: implications for preventing endocarditis.
The Journal of antimicrobial chemotherapy.
1984 Aug; 14(2):157-63. doi:
10.1093/jac/14.2.157. [PMID: 6334070] - T B Tjandramaga, A Van Hecken, A Mullie, R Verbesselt, P J De Schepper, L Verbist, K Josefsson. Relative bioavailability of enteric coated pellets, stearate and ethylsuccinate formulations of erythromycin.
Pharmacology.
1984; 29(6):305-11. doi:
10.1159/000138029. [PMID: 6334320] - R A Walstad, K B Hellum. Penetration of erythromycin in respiratory tract infections.
Acta oto-laryngologica. Supplementum.
1984; 407(?):50-4. doi:
10.3109/00016488409124965. [PMID: 6333775] - C H Pai, F Gillis, E Tuomanen, M I Marks. Erythromycin in treatment of Campylobacter enteritis in children.
American journal of diseases of children (1960).
1983 Mar; 137(3):286-8. doi:
10.1001/archpedi.1983.02140290072019. [PMID: 6600579] - T Yoshida, T Watanabe, T Shomura, S Someya, R Okamoto, S Ishihara, K Miyauchi, Y Kazuno. Bacteriological evaluation of midecamycin acetate and its metabolites.
The Japanese journal of antibiotics.
1982 Jun; 35(6):1462-74. doi:
NULL. [PMID: 6982352] - L Sundberg, T Edén, S Ernstson. The penetration of erythromycin into Waldeyer's ring--tonsil and adenoid tissue.
Infection.
1982; 10 Suppl 2(?):S105-7. doi:
10.1007/bf01640866. [PMID: 6980840] - J G McGimpsey, C H Webb, P H McCrea. Comparison of serum erythromycin concentration following administration of 100 mg erythromycin ethyl succinate intramuscularly and 500 mg erythromycin stearate orally.
International journal of oral surgery.
1981; 10(Suppl 1):198-202. doi:
NULL. [PMID: 6807878] - N M Alykov. [Photometric determination of monomycin in biological materials].
Antibiotiki.
1980 Dec; 25(12):911-4. doi:
NULL. [PMID: 6781403] - P J Thompson, K R Burgess, G E Marlin. Influence of food on absorption of erythromycin ethyl succinate.
Antimicrobial agents and chemotherapy.
1980 Nov; 18(5):829-31. doi:
10.1128/aac.18.5.829. [PMID: 6969579] - I A Vereshchagin. [Treatment of dysentery in children with a combination of monomycin and Eleutherococcus].
Antibiotiki.
1978 Jul; 23(7):633-6. doi:
. [PMID: 354512] - I A Vershchagin, S S Ivanova, E R Bukhteeva, L I Mukhina, R D Golosnaia. [Use of tablet forms of monomycin in children with acute dysentery].
Antibiotiki.
1977 Nov; 22(11):1028-31. doi:
. [PMID: 339824] - I A Vereshchagin. [Free amino acid content in the blood and urine from the use of monomycin on children with dysentery].
Antibiotiki.
1976 Aug; 21(8):754-8. doi:
. [PMID: 793513] - L T Danielova. [Quantitative determination of bound antibiotic in biological substrates after their enzymatic hydrolysis].
Antibiotiki.
1974 Nov; 19(11):1032-8. doi:
NULL. [PMID: 4617559] - A F Zak, N E Klimova. [The influence of test-animal age on antibiotic toxicity indices].
Antibiotiki.
1974 May; 19(5):454-8. doi:
NULL. [PMID: 4618770] - N K Unich. [Sensitivity of the microbial flora isolated from ill young children with acute gastrointestinal diseases to antibiotics, chemical preparations and polyvalent proteus phage].
Antibiotiki.
1974 Feb; 19(2):181-5. doi:
NULL. [PMID: 4377086] - R I Privalova. [The lactic acid microflora of the intestine and the effects of antibiotics on it].
Antibiotiki.
1974 Feb; 19(2):172-6. doi:
NULL. [PMID: 4618755] - I I Zolotarev, E G Aslamazov. [Side effects and complications of antibiotic therapy].
Urologiia i nefrologiia.
1974 Jan; ?(1):51-63. doi:
NULL. [PMID: 4374782] - A A Astapov, Iu A Amvrosiev, I B Tsynkalovskii. [Clinico-epidemiologic significance of episomal resistance to antibiotics in shigellae].
Zhurnal mikrobiologii, epidemiologii i immunobiologii.
1974; 00(5):71-5. doi:
NULL. [PMID: 4616591] - L T Danielova. [A method of determining the concentration of monomycin and neomycin in organ and tissue homogenates].
Antibiotiki.
1973 Nov; 18(11):1020-3. doi:
NULL. [PMID: 4595623] - P E Linnett, J L Strominger. Additional antibiotic inhibitors of peptidoglycan synthesis.
Antimicrobial agents and chemotherapy.
1973 Sep; 4(3):231-6. doi:
10.1128/aac.4.3.231. [PMID: 4202341] - E I Gurevich, E P Efimtseva. [Effect of Proteus vulgaris cytoplasm on non-specific resistance and combined use of monomycin and Proteus cytoplasm on aminoferase activity of experimental animal tissues].
Antibiotiki.
1973 Aug; 18(8):742-6. doi:
NULL. [PMID: 4590911] - A A Navasarian. [Effect of monomycin and paratyphoid serum on the dynamics of blood serum proteins].
Zhurnal eksperimental'noi i klinicheskoi meditsiny.
1973; 13(6):29-32. doi:
NULL. [PMID: 4139846] - R S Bray. Leishmaniasis in the Old World.
British medical bulletin.
1972 Jan; 28(1):39-43. doi:
10.1093/oxfordjournals.bmb.a070891. [PMID: 4562679] - G A Shakarian, A A Navasardian, R O Sedrakian, L A Ambartsumian. [Study of some clinical and immunological indices in antibiotic and serum therapy of experimental paratyphoid].
Zhurnal eksperimental'noi i klinicheskoi meditsiny.
1972; 12(1):27-34. doi:
NULL. [PMID: 4196736] - I A Vereschagin, A I Dobrovitskaia. [Effect of monomycin and neomycin on total blood lipid levels in children].
Antibiotiki.
1971 Nov; 16(11):1043-5. doi:
". [PMID: 4947969] - N V Velikorussova, S I Eidel'shteĭn. [Antibiotics and hearing].
Antibiotiki.
1971 Feb; 16(2):180-4. doi:
NULL. [PMID: 4104223] - G Ia Kivman, I Ia Geĭtman. [Characteristics of the determination of streptomycin and neomycin in blood serum by the agar diffusion method].
Antibiotiki.
1971; 16(4):331-5. doi:
NULL. [PMID: 4998597] - G V Skurkovich, T A Vasina, L I Tolkacheva, V I Kilachitskaia. [Dynamics of the distribution of rifocin in patients with chronic tonsillitis at different methods of administration].
Antibiotiki.
1970 Dec; 15(12):1117-20. doi:
NULL. [PMID: 4925642] - G F Abkarovich. [Characteristic of the causative agents of acute pneumonia isolated from patients treated with antibiotics].
Antibiotiki.
1970 Jul; 15(7):654-7. doi:
NULL. [PMID: 4321235] - M C Goodall. Ion dependent conductance: switching in lipid bilayers.
Nature.
1970 Mar; 225(5239):1257-8. doi:
10.1038/2251257a0. [PMID: 4907851] - G P Kaptsova. [Adverse effects of monomycin in infants].
Pediatriia.
1969 Jun; 48(6):68-70. doi:
NULL. [PMID: 4897983] - I Ia Geĭtman. [Effect of blood proteins on the antimicrobial effect of monomycin].
Antibiotiki.
1969 May; 14(5):433-6. doi:
NULL. [PMID: 4182158] - L E Gol'dberg, I P Belova. [Functional and morphologic changes of dog kidneys during parenteral administration of desoxystreptamine-containing antibiotics and streptomycin].
Antibiotiki.
1968 Dec; 13(12):1076-82. doi:
NULL. [PMID: 4888534] - L Nuzzolo, S Sanguigni, L Pierangeli, M Longhi. [Study on serum and urine concentrations of erythromycin succinate of pyrrolidine-methyl-tetracycline].
Archivio per le scienze mediche.
1968 Sep; 125(9):403-5. doi:
NULL. [PMID: 17340794] - L E Gol'dberg. [Effect of monomycin on the functional condition of kidneys in dogs].
Antibiotiki.
1968 Jan; 13(1):57-65. doi:
NULL. [PMID: 4873976] - L T Danielova, T K Sevian. [Method of determination of monomycin concentration in tissues].
Antibiotiki.
1967 Dec; 12(12):1082-4. doi:
NULL. [PMID: 4877312] - L E Gol'dberg. [Effect of kanamycin on the functional conduction of kidneys in rats and dogs].
Antibiotiki.
1967 Aug; 12(8):690-8. doi:
NULL. [PMID: 4871878] - L M Iakobson, V M Grigor'eva, A F Zak. [Thermolabile properties of blood serum and their effect on the indices of the biological activity of antibiotics].
Antibiotiki.
1967 Jun; 12(6):503-6. doi:
NULL. [PMID: 4970557] - F G Uglov, I K Lagert, A M Margolin, M S Poliak. [The use of antibiotics in surgical practice].
Vestnik khirurgii imeni I. I. Grekova.
1967 Jan; 98(1):7-12. doi:
NULL. [PMID: 4304565] - L E Gol'dberg. [Distribution in the body of dogs of antibiotics of water soluble bases from Actinomycetes and indices of blood clearance of these antibiotics].
Antibiotiki.
1967 Jan; 12(1):27-33. doi:
NULL. [PMID: 4968831] - A F Red'ko. [Dynamics of the change of the composition of microflora and its sensitivity toward antibiotics in purulent inflammatory processes of lungs].
Antibiotiki.
1966 Sep; 11(9):844-6. doi:
NULL. [PMID: 4385185] - A L Libov, I A Vereshchagina, I V Ivanova, L K Poliakova. [Problem of monomycin nephrotoxicity in children].
Antibiotiki.
1966 Apr; 11(4):382-3. doi:
NULL. [PMID: 4863962] - G I Kharchenko. [The action of antibiotics on the electrokinetic properties of blood serum proteins].
Antibiotiki.
1966 Jan; 11(1):69-73. doi:
NULL. [PMID: 4291643] - V A SHORIN, L E GAL'DBERG, V E KREMER. [Study on the effect of colimycin and monomycin on the renal function].
Antibiotiki.
1961 Aug; 6(?):705-10. doi:
NULL. [PMID: 13912259]