Exact Mass: 255.0507104
Exact Mass Matches: 255.0507104
Found 479 metabolites which its exact mass value is equals to given mass value 255.0507104,
within given mass tolerance error 0.05 dalton. Try search metabolite list with more accurate mass tolerance error
0.01 dalton.
2-Amino-6-[(1R,2S)-1,2,3-trihydroxypropyl]-7,8-dihydro-3H-pteridin-4-one
7,8-Dihydroneopterin, an inflammation marker, induces cellular apoptosis in astrocytes and neurons via enhancement of nitric oxide synthase (iNOS) expression. 7,8-Dihydroneopterin can be used in the research of neurodegenerative diseases[1].
Ketorolac
Ketorolac is only found in individuals that have used or taken this drug. It is a pyrrolizine carboxylic acid derivative structurally related to indomethacin. It is an NSAID and is used principally for its analgesic activity (from Martindale The Extra Pharmacopoeia, 31st ed). Ketorolac is a nonsteroidal anti-inflammatory drug (NSAID) chemically related to indomethacin and tolmetin. Ketorolac tromethamine is a racemic mixture of [-]S- and [+]R-enantiomeric forms, with the S-form having analgesic activity. Its antiinflammatory effects are believed to be due to inhibition of both cylooxygenase-1 (COX-1) and cylooxygenase-2 (COX-2) which leads to the inhibition of prostaglandin synthesis leading to decreased formation of precursors of prostaglandins and thromboxanes from arachidonic acid. The resultant reduction in prostaglandin synthesis and activity may be at least partially responsible for many of the adverse, as well as the therapeutic, effects of these medications. Analgesia is probably produced via a peripheral action in which blockade of pain impulse generation results from decreased prostaglandin activity. However, inhibition of the synthesis or actions of other substances that sensitize pain receptors to mechanical or chemical stimulation may also contribute to the analgesic effect. In terms of the ophthalmic applications of ketorolac - ocular administration of ketorolac reduces prostaglandin E2 levels in aqueous humor, secondary to inhibition of prostaglandin biosynthesis. M - Musculo-skeletal system > M01 - Antiinflammatory and antirheumatic products > M01A - Antiinflammatory and antirheumatic products, non-steroids > M01AB - Acetic acid derivatives and related substances S - Sensory organs > S01 - Ophthalmologicals > S01B - Antiinflammatory agents > S01BC - Antiinflammatory agents, non-steroids D018501 - Antirheumatic Agents > D000894 - Anti-Inflammatory Agents, Non-Steroidal > D016861 - Cyclooxygenase Inhibitors C78272 - Agent Affecting Nervous System > C241 - Analgesic Agent > C2198 - Nonnarcotic Analgesic D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents D002491 - Central Nervous System Agents > D000700 - Analgesics C471 - Enzyme Inhibitor > C1323 - Cyclooxygenase Inhibitor D000893 - Anti-Inflammatory Agents D004791 - Enzyme Inhibitors
Sulfathiazole
C9H9N3O2S2 (255.01361740000002)
Sulfathiazole is only found in individuals that have used or taken this drug.It is a short-acting sulfa drug. It used to be a common oral and topical antimicrobial until less toxic alternatives were discovered. It is still occasionally used, sometimes in combination with sulfabenzamide and sulfacetamide. CONFIDENCE standard compound; INTERNAL_ID 1024; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 2323; ORIGINAL_PRECURSOR_SCAN_NO 2321 CONFIDENCE standard compound; INTERNAL_ID 1024; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 2327; ORIGINAL_PRECURSOR_SCAN_NO 2325 CONFIDENCE standard compound; INTERNAL_ID 1024; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7417; ORIGINAL_PRECURSOR_SCAN_NO 7415 CONFIDENCE standard compound; INTERNAL_ID 1024; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 2326; ORIGINAL_PRECURSOR_SCAN_NO 2324 CONFIDENCE standard compound; INTERNAL_ID 1024; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 2315; ORIGINAL_PRECURSOR_SCAN_NO 2312 CONFIDENCE standard compound; INTERNAL_ID 1024; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7355; ORIGINAL_PRECURSOR_SCAN_NO 7354 CONFIDENCE standard compound; INTERNAL_ID 1024; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7401; ORIGINAL_PRECURSOR_SCAN_NO 7397 CONFIDENCE standard compound; INTERNAL_ID 1024; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7346; ORIGINAL_PRECURSOR_SCAN_NO 7344 CONFIDENCE standard compound; INTERNAL_ID 1024; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 2323; ORIGINAL_PRECURSOR_SCAN_NO 2320 CONFIDENCE standard compound; INTERNAL_ID 1024; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 2314; ORIGINAL_PRECURSOR_SCAN_NO 2312 CONFIDENCE standard compound; INTERNAL_ID 1024; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7406; ORIGINAL_PRECURSOR_SCAN_NO 7404 CONFIDENCE standard compound; INTERNAL_ID 1024; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7390; ORIGINAL_PRECURSOR_SCAN_NO 7388 D - Dermatologicals > D06 - Antibiotics and chemotherapeutics for dermatological use > D06B - Chemotherapeutics for topical use > D06BA - Sulfonamides J - Antiinfectives for systemic use > J01 - Antibacterials for systemic use > J01E - Sulfonamides and trimethoprim > J01EB - Short-acting sulfonamides C254 - Anti-Infective Agent > C29739 - Sulfonamide Anti-Infective Agent D000890 - Anti-Infective Agents > D013432 - Sulfathiazoles D000890 - Anti-Infective Agents > D013424 - Sulfanilamides CONFIDENCE standard compound; EAWAG_UCHEM_ID 185 CONFIDENCE standard compound; INTERNAL_ID 2360 CONFIDENCE standard compound; INTERNAL_ID 1023 KEIO_ID S079; [MS2] KO009251 KEIO_ID S079
Phosfolan
ORIGINAL_ACQUISITION_NO 7370; CONFIDENCE standard compound; INTERNAL_ID 1078; DATASET 20200303_ENTACT_RP_MIX503; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_PRECURSOR_SCAN_NO 7368 CONFIDENCE standard compound; INTERNAL_ID 1078; DATASET 20200303_ENTACT_RP_MIX503; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7337; ORIGINAL_PRECURSOR_SCAN_NO 7335 CONFIDENCE standard compound; INTERNAL_ID 1078; DATASET 20200303_ENTACT_RP_MIX503; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7325; ORIGINAL_PRECURSOR_SCAN_NO 7323 CONFIDENCE standard compound; INTERNAL_ID 1078; DATASET 20200303_ENTACT_RP_MIX503; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7376; ORIGINAL_PRECURSOR_SCAN_NO 7374 CONFIDENCE standard compound; INTERNAL_ID 1078; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7406; ORIGINAL_PRECURSOR_SCAN_NO 7404 CONFIDENCE standard compound; INTERNAL_ID 1078; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7355; ORIGINAL_PRECURSOR_SCAN_NO 7354 CONFIDENCE standard compound; INTERNAL_ID 1078; DATASET 20200303_ENTACT_RP_MIX503; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7370; ORIGINAL_PRECURSOR_SCAN_NO 7368
Propyzamide
CONFIDENCE standard compound; INTERNAL_ID 1234; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4824; ORIGINAL_PRECURSOR_SCAN_NO 4823 CONFIDENCE standard compound; INTERNAL_ID 1234; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4820; ORIGINAL_PRECURSOR_SCAN_NO 4819 CONFIDENCE standard compound; INTERNAL_ID 1234; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9401; ORIGINAL_PRECURSOR_SCAN_NO 9399 CONFIDENCE standard compound; INTERNAL_ID 1234; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4852; ORIGINAL_PRECURSOR_SCAN_NO 4849 CONFIDENCE standard compound; INTERNAL_ID 1234; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9371; ORIGINAL_PRECURSOR_SCAN_NO 9366 CONFIDENCE standard compound; INTERNAL_ID 1234; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4851; ORIGINAL_PRECURSOR_SCAN_NO 4850 CONFIDENCE standard compound; INTERNAL_ID 1234; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4792; ORIGINAL_PRECURSOR_SCAN_NO 4790 CONFIDENCE standard compound; EAWAG_UCHEM_ID 3175 CONFIDENCE standard compound; INTERNAL_ID 2321 CONFIDENCE standard compound; INTERNAL_ID 8467
Imidacloprid
C9H10ClN5O2 (255.05229900000003)
Imidacloprid is an insecticide Imidacloprid is a neonicotinoid, which is a class of neuro-active insecticides modeled after nicotine. Imidacloprid is a patented chemical, Imidacloprid is manufactured by Bayer Cropscience (part of Bayer AG) and sold under trade names Kohinor, Admire, Advantage, Gaucho, Merit, Confidor, Hachikusan, Premise, Prothor, and Winner. It is marketed as pest control, seed treatment, an insecticide spray, termite control, flea control, and a systemic insecticide. CONFIDENCE standard compound; INTERNAL_ID 60; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 6493; ORIGINAL_PRECURSOR_SCAN_NO 6491 CONFIDENCE standard compound; INTERNAL_ID 60; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 6445; ORIGINAL_PRECURSOR_SCAN_NO 6444 CONFIDENCE standard compound; INTERNAL_ID 60; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3049; ORIGINAL_PRECURSOR_SCAN_NO 3048 CONFIDENCE standard compound; INTERNAL_ID 60; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3058; ORIGINAL_PRECURSOR_SCAN_NO 3055 CONFIDENCE standard compound; INTERNAL_ID 60; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 6460; ORIGINAL_PRECURSOR_SCAN_NO 6459 CONFIDENCE standard compound; INTERNAL_ID 60; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 6485; ORIGINAL_PRECURSOR_SCAN_NO 6481 CONFIDENCE standard compound; INTERNAL_ID 60; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3058; ORIGINAL_PRECURSOR_SCAN_NO 3056 CONFIDENCE standard compound; INTERNAL_ID 60; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 6489; ORIGINAL_PRECURSOR_SCAN_NO 6486 CONFIDENCE standard compound; INTERNAL_ID 60; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3125; ORIGINAL_PRECURSOR_SCAN_NO 3122 CONFIDENCE standard compound; INTERNAL_ID 60; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3059; ORIGINAL_PRECURSOR_SCAN_NO 3056 D010575 - Pesticides > D007306 - Insecticides > D000073943 - Neonicotinoids D018377 - Neurotransmitter Agents > D018678 - Cholinergic Agents CONFIDENCE standard compound; EAWAG_UCHEM_ID 2709 CONFIDENCE standard compound; INTERNAL_ID 3036 CONFIDENCE standard compound; INTERNAL_ID 2322 CONFIDENCE standard compound; INTERNAL_ID 8394 D016573 - Agrochemicals Insecticide
Ganciclovir
Ganciclovir is only found in individuals that have used or taken this drug. It is an acyclovir analog that is a potent inhibitor of the Herpesvirus family including cytomegalovirus. Ganciclovir is used to treat complications from AIDS-associated cytomegalovirus infections. [PubChem]Ganciclovirs antiviral activity inhibits virus replication. This inhibitory action is highly selective as the drug must be converted to the active form by a virus-encoded cellular enzyme, thymidine kinase (TK). TK catalyzes phosphorylation of ganciclovir to the monophosphate, which is then subsequently converted into the diphosphate by cellular guanylate kinase and into the triphosphate by a number of cellular enzymes. In vitro, ganciclovir triphosphate stops replication of herpes viral DNA. When used as a substrate for viral DNA polymerase, ganciclovir triphosphate competitively inhibits dATP leading to the formation of faulty DNA. This is where ganciclovir triphosphate is incorporated into the DNA strand replacing many of the adenosine bases. This results in the prevention of DNA synthesis, as phosphodiester bridges can longer to be built, destabilizing the strand. Ganciclovir inhibits viral DNA polymerases more effectively than it does cellular polymerase, and chain elongation resumes when ganciclovir is removed. J - Antiinfectives for systemic use > J05 - Antivirals for systemic use > J05A - Direct acting antivirals > J05AB - Nucleosides and nucleotides excl. reverse transcriptase inhibitors S - Sensory organs > S01 - Ophthalmologicals > S01A - Antiinfectives > S01AD - Antivirals D000890 - Anti-Infective Agents > D000998 - Antiviral Agents C471 - Enzyme Inhibitor > C29575 - DNA Polymerase Inhibitor C254 - Anti-Infective Agent > C281 - Antiviral Agent KEIO_ID G088; [MS2] KO008989 KEIO_ID G088 Ganciclovir (BW 759), a nucleoside analogue, is an orally active antiviral agent with activity against CMV. Ganciclovir also has activity in vitro against members of the herpes group and some other DNA viruses. Ganciclovir inhibits the in vitro replication of human herpes viruses (HSV 1 and 2, CMV) and adenovirus serotypes 1, 2, 4, 6, 8, 10, 19, 22 and 28. Ganciclovir has an IC50 of 5.2 μM for feline herpesvirus type-1 (FHV-1) and can diffuse into the brain[1][2][3].
Apigenidin
Apigenidin is a member of the class of compounds known as 7-hydroxyflavonoids. 7-hydroxyflavonoids are flavonoids that bear one hydroxyl group at the C-7 position of the flavonoid skeleton. Apigenidin is practically insoluble (in water) and a very weakly acidic compound (based on its pKa). Apigenidin can be found in corn, which makes apigenidin a potential biomarker for the consumption of this food product. Apigeninidin. CAS Common Chemistry. CAS, a division of the American Chemical Society, n.d. https://commonchemistry.cas.org/detail?cas_rn=1151-98-0 (retrieved 2024-09-18) (CAS RN: 1151-98-0). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).
Nicotinamide riboside
Nicotinamide riboside is involved in nicotinate and nicotinamide metabolism. Nicotinamide riboside was originally identified as a nutrient in milk. It is a useful compound for the elevation of NAD+ levels in humans. Nicotinamide riboside has recently been discovered to be an NAD(+) precursor that is converted into nicotinamide mononucleotide by specific nicotinamide riboside kinases, Nrk1 and Nrk2. It has been shown that exogenous nicotinamide riboside promotes Sir2-dependent repression of recombination, improves gene silencing, and extends the lifespan of certain animal models without calorie restriction (PMID: 17482543). Supplementation in mammalian cells and mouse tissues increases NAD(+) levels and activates SIRT1 and SIRT3, culminating in enhanced oxidative metabolism and protection against high-fat diet-induced metabolic abnormalities (PMID: 22682224). Recent data suggest that nicotinamide riboside may be the only vitamin precursor that supports neuronal NAD+ synthesis (PMID: 18429699). Nicotinamide riboside kinase has an essential role in the phosphorylation of nicotinamide riboside and the cancer drug tiazofurin (PMID: 15137942). Nicotinamide riboside is involved in nicotinate and nicotinamide metabolism. Nicotinamide riboside has been identified as a nutrient in milk. It is a useful compound for elevation of NAD+ levels in humans. Recent data suggest that nicotinamide riboside may be the only vitamin precursor that supports neuronal NAD+ synthesis (PMID: 18429699). Nicotinamide riboside kinase has an essential role for phosphorylation of nicotinamide riboside and the cancer drug tiazofurin (PMID 15137942). [HMDB] COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials, COVID-19 Disease Map C26170 - Protective Agent > C275 - Antioxidant Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS
3-Methoxy-8,9-methylenedioxy-3,4-dihydrophenanthridine
Sulbactam sodium
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D065093 - beta-Lactamase Inhibitors D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D047090 - beta-Lactams D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D010406 - Penicillins D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D007769 - Lactams C2140 - Adjuvant > C183118 - Beta-lactamase Inhibitor D004791 - Enzyme Inhibitors Same as: D02223
lamotrigine
D002492 - Central Nervous System Depressants > D014149 - Tranquilizing Agents > D014150 - Antipsychotic Agents D002491 - Central Nervous System Agents > D011619 - Psychotropic Drugs > D014149 - Tranquilizing Agents D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants C78272 - Agent Affecting Nervous System > C264 - Anticonvulsant Agent D002317 - Cardiovascular Agents > D002121 - Calcium Channel Blockers D002491 - Central Nervous System Agents > D000927 - Anticonvulsants D002317 - Cardiovascular Agents > D026941 - Sodium Channel Blockers N - Nervous system > N03 - Antiepileptics > N03A - Antiepileptics D000077264 - Calcium-Regulating Hormones and Agents D049990 - Membrane Transport Modulators CONFIDENCE standard compound; INTERNAL_ID 1528 CONFIDENCE Reference Standard (Level 1); INTERNAL_ID 86 CONFIDENCE standard compound; EAWAG_UCHEM_ID 2676
N-(3-Chloro-4-morpholinophenyl)-N-hydroxyformimidamide
7,8-Dihydroneopterin
7,8-Dihydroneopterin, also known as dihydroneopterin, belongs to the class of organic compounds known as biopterins and derivatives. These are coenzymes containing a 2-amino-pteridine-4-one derivative. They are synthesized in several parts of the body, including the pineal gland. 7,8-Dihydroneopterin is a strong basic compound (based on its pKa). Within humans, 7,8-dihydroneopterin participates in a number of enzymatic reactions. In particular, 7,8-dihydroneopterin can be biosynthesized from sepiapterin; which is catalyzed by the enzyme sepiapterin reductase or carbonyl reductase [NADPH] 1. In humans, 7,8-dihydroneopterin is involved in the metabolic disorder called hyperphenylalaninemia due to 6-pyruvoyltetrahydropterin synthase (PTPS) deficiency. 7,8-Dihydroneopterin is produced by human monocyte-derived macrophages upon stimulation with interferon-gamma. Increased amounts of 7,8-dihydroneopterin in human body fluids are found in many disorders, including viral infections and autoimmune diseases (PMID: 12804528). 7,8-dihydroneopterin, also known as npr, belongs to biopterins and derivatives class of compounds. Those are coenzymes containing a 2-amino-pteridine-4-one derivative. They are mainly synthesized in several parts of the body, including the pineal gland. 7,8-dihydroneopterin is slightly soluble (in water) and a very weakly acidic compound (based on its pKa). 7,8-dihydroneopterin can be found in a number of food items such as prickly pear, star anise, cocoa bean, and black salsify, which makes 7,8-dihydroneopterin a potential biomarker for the consumption of these food products. 7,8-dihydroneopterin exists in all living organisms, ranging from bacteria to humans. In humans, 7,8-dihydroneopterin is involved in the pterine biosynthesis. 7,8-dihydroneopterin is also involved in several metabolic disorders, some of which include hyperphenylalaninemia due to dhpr-deficiency, sepiapterin reductase deficiency, dopa-responsive dystonia, and hyperphenylalaniemia due to guanosine triphosphate cyclohydrolase deficiency. 7,8-Dihydroneopterin, an inflammation marker, induces cellular apoptosis in astrocytes and neurons via enhancement of nitric oxide synthase (iNOS) expression. 7,8-Dihydroneopterin can be used in the research of neurodegenerative diseases[1].
Lamotrigine
Lamotrigine is an anticonvulsant drug used in the treatment of epilepsy and bipolar disorder. For epilepsy it is used to treat partial seizures, primary and secondary tonic-clonic seizures, and seizures associated with Lennox-Gastaut syndrome. Lamotrigine also acts as a mood stabilizer. It is the first medication since lithium granted Food and Drug Administration (FDA) approval for the maintenance treatment of bipolar type I. Chemically unrelated to other anticonvulsants, lamotrigine has relatively few side-effects and does not require blood monitoring. The exact way lamotrigine works is unknown. [Wikipedia] D002492 - Central Nervous System Depressants > D014149 - Tranquilizing Agents > D014150 - Antipsychotic Agents D002491 - Central Nervous System Agents > D011619 - Psychotropic Drugs > D014149 - Tranquilizing Agents D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants C78272 - Agent Affecting Nervous System > C264 - Anticonvulsant Agent D002317 - Cardiovascular Agents > D002121 - Calcium Channel Blockers D002491 - Central Nervous System Agents > D000927 - Anticonvulsants D002317 - Cardiovascular Agents > D026941 - Sodium Channel Blockers N - Nervous system > N03 - Antiepileptics > N03A - Antiepileptics D000077264 - Calcium-Regulating Hormones and Agents D049990 - Membrane Transport Modulators
1-Hydroxy-3-methoxy-10-methylacridone
1-Hydroxy-3-methoxy-10-methylacridone is found in herbs and spices. 1-Hydroxy-3-methoxy-10-methylacridone is an alkaloid from the roots Ruta graveolens (rue
Clausine L
Clausine L is found in herbs and spices. Clausine L is an alkaloid from stem bark of Murraya koenigii (curryleaf tree
Methyl 6-methoxy-9H-carbazole-3-carboxylate
Methyl 6-methoxy-9H-carbazole-3-carboxylate is found in fruits. Methyl 6-methoxy-9H-carbazole-3-carboxylate is an alkaloid from the roots of Clausena lansium (wampee). Alkaloid from the roots of Clausena lansium (wampee). Methyl 6-methoxy-9H-carbazole-3-carboxylate is found in fruits.
1,6-Dimethoxy-9H-carbazole-3-carboxaldehyde
1,6-Dimethoxy-9H-carbazole-3-carboxaldehyde is found in fruits. 1,6-Dimethoxy-9H-carbazole-3-carboxaldehyde is an alkaloid from the roots of Clausena lansium (wampee). Alkaloid from the roots of Clausena lansium (wampee). 1,6-Dimethoxy-9H-carbazole-3-carboxaldehyde is found in fruits.
Mukonine
Mukonine is found in herbs and spices. Mukonine is an alkaloid from the stem bark of Murraya koenigii (curryleaf tree
Pranoprofen
S - Sensory organs > S01 - Ophthalmologicals > S01B - Antiinflammatory agents > S01BC - Antiinflammatory agents, non-steroids C78272 - Agent Affecting Nervous System > C241 - Analgesic Agent > C2198 - Nonnarcotic Analgesic Pranoprofen (INN) is a non-steroidal anti-inflammatory drug used in ophthalmology. D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents D002491 - Central Nervous System Agents > D000700 - Analgesics D018501 - Antirheumatic Agents > D006074 - Gout Suppressants D000893 - Anti-Inflammatory Agents
N-(3-Chloro-4-morpholinophenyl)-N'-hydroxyformimidamide
Alrestatin
D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents > D010276 - Parasympatholytics C471 - Enzyme Inhibitor > C72880 - Aldose Reductase Inhibitor D004791 - Enzyme Inhibitors
Amfenac
C78272 - Agent Affecting Nervous System > C241 - Analgesic Agent > C2198 - Nonnarcotic Analgesic
4-Methyl-2-oxo-2H-chromen-7-yl sulfamate
C10H9NO5S (255.02014239999997)
Flosequinoxan
C11H10FNO3S (255.03654020000002)
Irsogladine
C78276 - Agent Affecting Digestive System or Metabolism > C29701 - Anti-ulcer Agent D020011 - Protective Agents > D011837 - Radiation-Protective Agents D005765 - Gastrointestinal Agents > D000897 - Anti-Ulcer Agents D020011 - Protective Agents > D016588 - Anticarcinogenic Agents D000970 - Antineoplastic Agents Irsogladine is a PDE4 inhibitor and muscarinic acetylcholine receptor binder. Target: PDE4; mACHR Irsogladine treatment (300 and 500 mg/kg/day) resulted in a dose-dependent reduction of angiogenesis in wild-type mice by 21 and 45.3\% (P < 0.02, P < 0.001), in tPA-deficient mice by 42.6 and 46\% (P < 0.001, P < 0.001), and in uPA-deficient mice by 27.2 and 46\% (P < 0.05, p < 0.001), respectively. Irsogladine inhibits bFGF-induced angiogenesis in wild-type, tPA-knockout, and uPA-knockout mice [1]. Irsogladine up-regulates GJIC between PC cells via regulation of the PKA pathway. It also suggests a useful adjuvant of Irsogladine to pancreatic cancer therapy [2]. irsogladine produces the increase of intracellular cAMP content via non-selective inhibition of PDE isozymes, which may be a key mechanism involved in its gastroprotective actions [3].
N7-(2-((Hydroxyethyl)thio)ethyl)guanine
2-Amino-7-[(2R)-2,3-dihydroxypropanoyl]-5,6,7,8-tetrahydro-3H-pteridin-4-one
7,8-dihydromonapterin
7,8-dihydromonapterin, also known as dhm or h2-mpt, belongs to biopterins and derivatives class of compounds. Those are coenzymes containing a 2-amino-pteridine-4-one derivative. They are mainly synthesized in several parts of the body, including the pineal gland. 7,8-dihydromonapterin is slightly soluble (in water) and an extremely strong acidic compound (based on its pKa). 7,8-dihydromonapterin can be found in a number of food items such as mugwort, pineapple, eggplant, and japanese pumpkin, which makes 7,8-dihydromonapterin a potential biomarker for the consumption of these food products.
beta-D-ribosylnicotinate
C11H13NO6 (255.07428380000002)
beta-d-ribosylnicotinate is slightly soluble (in water) and a moderately acidic compound (based on its pKa). beta-d-ribosylnicotinate can be found in a number of food items such as turnip, chanterelle, garland chrysanthemum, and canola, which makes beta-d-ribosylnicotinate a potential biomarker for the consumption of these food products.
((2-(Aminocarbonyl)-5-ethoxyphenyl)thio)acetic acid
6-[2-(trifluoromethyl)phenyl]-1,3,5-triazine-2,4-diamine
C10H8F3N5 (255.07317640000002)
2-N-[3-(trifluoromethyl)phenyl]-1,3,5-triazine-2,4-diamine
C10H8F3N5 (255.07317640000002)
5-Phenyl-3-tetrahydro-1H-pyrrol-1-ylisothiazole-4-carbonitrile
2-(2-hydroxypropyl)benzo[de]isoquinoline-1,3-dione
Irsogladine
C78276 - Agent Affecting Digestive System or Metabolism > C29701 - Anti-ulcer Agent D020011 - Protective Agents > D011837 - Radiation-Protective Agents D005765 - Gastrointestinal Agents > D000897 - Anti-Ulcer Agents D020011 - Protective Agents > D016588 - Anticarcinogenic Agents D000970 - Antineoplastic Agents Irsogladine is a PDE4 inhibitor and muscarinic acetylcholine receptor binder. Target: PDE4; mACHR Irsogladine treatment (300 and 500 mg/kg/day) resulted in a dose-dependent reduction of angiogenesis in wild-type mice by 21 and 45.3\% (P < 0.02, P < 0.001), in tPA-deficient mice by 42.6 and 46\% (P < 0.001, P < 0.001), and in uPA-deficient mice by 27.2 and 46\% (P < 0.05, p < 0.001), respectively. Irsogladine inhibits bFGF-induced angiogenesis in wild-type, tPA-knockout, and uPA-knockout mice [1]. Irsogladine up-regulates GJIC between PC cells via regulation of the PKA pathway. It also suggests a useful adjuvant of Irsogladine to pancreatic cancer therapy [2]. irsogladine produces the increase of intracellular cAMP content via non-selective inhibition of PDE isozymes, which may be a key mechanism involved in its gastroprotective actions [3].
Amfenac
C78272 - Agent Affecting Nervous System > C241 - Analgesic Agent > C2198 - Nonnarcotic Analgesic
3,7-Dimethoxy-4-methyl-5H-indeno[1,2-b]pyridin-5-one
(2S) 1,4-dimethyl-2-O-(1H-pyrrole-2-carbonyloxy)-malate
C11H13NO6 (255.07428380000002)
6-<(Ethoxythio)carbonyl>pyridin-2-carbonsaeure-ethylester|6-<(ethoxythio)carbonyl>pyridin-2-carbonsaeureethylester|6-[(ethoxythio)carbonyl]pyridin-2-carbonsaeureethylester
nicotinate ribose
C11H13NO6 (255.07428380000002)
D-ribosylnicotinate is conjugate base of D-ribosylnicotinic acid. It has a role as a human metabolite. It is a conjugate base of a D-ribosylnicotinic acid. Nicotinic acid riboside is a natural product found in Vitis vinifera, Saccharomyces cerevisiae, and Homo sapiens with data available. Conjugate base of D-ribosylnicotinic acid. Nicotinic acid riboside is a NAD+ precursor in human cells. Nicotinic acid riboside is an authentic intermediate of human NAD+ metabolism[1][2].
ketorolac
M - Musculo-skeletal system > M01 - Antiinflammatory and antirheumatic products > M01A - Antiinflammatory and antirheumatic products, non-steroids > M01AB - Acetic acid derivatives and related substances S - Sensory organs > S01 - Ophthalmologicals > S01B - Antiinflammatory agents > S01BC - Antiinflammatory agents, non-steroids D018501 - Antirheumatic Agents > D000894 - Anti-Inflammatory Agents, Non-Steroidal > D016861 - Cyclooxygenase Inhibitors C78272 - Agent Affecting Nervous System > C241 - Analgesic Agent > C2198 - Nonnarcotic Analgesic D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents D002491 - Central Nervous System Agents > D000700 - Analgesics C471 - Enzyme Inhibitor > C1323 - Cyclooxygenase Inhibitor D000893 - Anti-Inflammatory Agents D004791 - Enzyme Inhibitors This spectrum was obtained at The Multidisciplinary Research Laboratory at Antenor Orrego Private University, Trujillo, La Libertad, Peru.The sample was obtained from a pharmacy.; The sample was dissolved in 1:1 acetonitrile:water and passed through a ACQUITY UPLC BEH C18 1.7um column at 0.6 mL/min in ramp of MPA: 0.1\\% Formic Acid in water; MPB: 0.1\\% Formic Acid in Acetonitrile; Contact us: http://www.upao.edu.pe/labinm/
Pranoprofen
S - Sensory organs > S01 - Ophthalmologicals > S01B - Antiinflammatory agents > S01BC - Antiinflammatory agents, non-steroids C78272 - Agent Affecting Nervous System > C241 - Analgesic Agent > C2198 - Nonnarcotic Analgesic D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents D002491 - Central Nervous System Agents > D000700 - Analgesics D018501 - Antirheumatic Agents > D006074 - Gout Suppressants D000893 - Anti-Inflammatory Agents
sulfathiazole
C9H9N3O2S2 (255.01361740000002)
D - Dermatologicals > D06 - Antibiotics and chemotherapeutics for dermatological use > D06B - Chemotherapeutics for topical use > D06BA - Sulfonamides J - Antiinfectives for systemic use > J01 - Antibacterials for systemic use > J01E - Sulfonamides and trimethoprim > J01EB - Short-acting sulfonamides C254 - Anti-Infective Agent > C29739 - Sulfonamide Anti-Infective Agent D000890 - Anti-Infective Agents > D013432 - Sulfathiazoles D000890 - Anti-Infective Agents > D013424 - Sulfanilamides
methyl 2-[(2,3-dihydroxybenzoyl)amino]-3-hydroxypropanoate
C11H13NO6 (255.07428380000002)
C15H13NO3_2(1H)-Quinolinone, 3,4-dihydro-3,4-dihydroxy-4-phenyl
methyl 2-[(2,3-dihydroxybenzoyl)amino]-3-hydroxypropanoate
C11H13NO6 (255.07428380000002)
Imidacloprid
C9H10ClN5O2 (255.05229900000003)
D010575 - Pesticides > D007306 - Insecticides > D000073943 - Neonicotinoids D018377 - Neurotransmitter Agents > D018678 - Cholinergic Agents D016573 - Agrochemicals
3-phenyl-2-sulfanylidene-1H-pyrido[2,3-d]pyrimidin-4-one
C13H9N3OS (255.04663039999997)
5-Chloro-1,3-dihydro-3-(phenylmethylene)-2H-indol-2-one
dimethyl 5-methyl-2,3-dihydropyrrolo[2,1-b][1,3]thiazole-6,7-dicarboxylate
3-[Cyano(2,4-Dichlorophenyl)Methylene]Carbazamidine
Methyl 4-Hydroxy-2H-1,2-benzothiazine-3-carboxylate 1,1-Dioxide
C10H9NO5S (255.02014239999997)
(+/-)-1-methoxy-1-(trifluoromethyl)phenylacetyl chloride
C10H11ClF3O2 (255.03996320000002)
1H-Indole-2-carboxamide,5-fluoro-N-2-pyridinyl-(9CI)
2,3,4,5-TETRAHYDRO-3-(TRIFLUOROACETYL)-1,5-METHANO-1H-3-BENZ AZEPINE
C13H12F3NO (255.08709379999996)
2,4-DIAMINO-6-[3-(TRIFLUOROMETHYL)PHENYL]-1,3,5-TRIAZINE
C10H8F3N5 (255.07317640000002)
N-(3-TRIFLUOROMETHYL-PHENYL)-[1,3,5]TRIAZINE-2,4-DIAMINE
C10H8F3N5 (255.07317640000002)
Methyl (R)-3-acetamido-3-(4-chlorophenyl)propanoate
ethyl 2-methoxy-4-(trifluoromethyl)-1,3-thiazole-5-carboxylate
4-[6-(1,2,4-oxadiazol-3-yl)pyrimidin-4-yl]oxyaniline
C12H9N5O2 (255.07562140000002)
METHYL 2-CHLORO-4-(1H-PYRAZOL-1-YL)BENZENECARBOXYLATE
ethyl 4,5-dimethoxy-2-nitrobenzoate
C11H13NO6 (255.07428380000002)
7-chloro-8-methylquinoline-2-carboximidamide,hydrochloride
6-chloro-8-methylquinoline-2-carboximidamide,hydrochloride
1,3,5-TRIAZINE-2,4-DIAMINE, 6-[4-(TRIFLUOROMETHYL)PHENYL]-
C10H8F3N5 (255.07317640000002)
3-methyl-4-(trifluoromethoxy)pyridine-2-carboximidamide,hydrochloride
4-(2,2,2-trifluoroethoxy)pyridine-2-carboximidamide,hydrochloride
METHYL 4-CYANO-3-FLUORO-[1,1-BIPHENYL]-3-CARBOXYLATE
C15H10FNO2 (255.06955320000003)
METHYL 2-CYANO-5-FLUORO-[1,1-BIPHENYL]-3-CARBOXYLATE
C15H10FNO2 (255.06955320000003)
METHYL 3-CYANO-5-FLUORO-[1,1-BIPHENYL]-3-CARBOXYLATE
C15H10FNO2 (255.06955320000003)
METHYL 4-CYANO-5-FLUORO-[1,1-BIPHENYL]-3-CARBOXYLATE
C15H10FNO2 (255.06955320000003)
METHYL 3-CYANO-3-FLUORO-[1,1-BIPHENYL]-4-CARBOXYLATE
C15H10FNO2 (255.06955320000003)
METHYL 4-CYANO-3-FLUORO-[1,1-BIPHENYL]-4-CARBOXYLATE
C15H10FNO2 (255.06955320000003)
METHYL 4-CYANO-4-FLUORO-[1,1-BIPHENYL]-3-CARBOXYLATE
C15H10FNO2 (255.06955320000003)
3-(METHYLCARBAMOYL)-[1,1-BIPHENYL]-2-CARBOXYLIC ACID
methyl 2-(isocyanatosulfonylmethyl)benzoate
C10H9NO5S (255.02014239999997)
5-chloro-8-methylquinoline-2-carboximidamide,hydrochloride
5-pyridin-2-ylthiophene-2-sulfonohydrazide
C9H9N3O2S2 (255.01361740000002)
3-(6-CHLORO-2H-1,4-BENZOXAZIN-3(4H)-ONE-4-YL)PROPIONICACID
2-(2,4-Difluorophenyl)-3-(1H-1,2,4-triazol-1-yl)-1,2-propanediol
2-(5-bromo-1,2,3,4-tetrahydroisoquinolin-4-yl)ethanol
Methyl 6-chloro-3-(Methylthio)-1H-indole-5-carboxylate
1-(5-Bromopyrimidin-2-yl)-4-piperidinone
C9H10BrN3O (255.00071899999998)
METHYL 6-CHLORO-4-METHYL-3-OXO-3,4-DIHYDRO-2H-BENZO[B][1,4]OXAZINE-8-CARBOXYLATE
5-((4-CHLORO-2-METHYLPHENOXY)METHYL)-4H-1,2,4-TRIAZOLE-3-THIOL
2-Methoxy-4-morpholinobenzenediazonium chloride zinc chloride double salt
4-fluoro-N-(2-furylmethyl)benzenesulfonamide
C11H10FNO3S (255.03654020000002)
2-AMINO-2-(3-(TRIFLUOROMETHYL)PHENYL)ACETIC ACID HYDROCHLORIDE
C9H9ClF3NO2 (255.02738800000003)
1,3-Dioxo-2-isoindolineethanesulfonic acid
C10H9NO5S (255.02014239999997)
1-(5-chloro-6-methylpyrazin-2-yl)piperidine-4-carboxylic acid
methyl 4-(4-fluoro-5-methyl-2-nitrophenyl)butanoate
C12H14FNO4 (255.09068159999998)
4-CHLORO-6-(METHOXYMETHYL)-2-(2-METHYL-1,3-THIAZOL-4-YL)PYRIMIDINE
1-((4-TRIFLUOROMETHYLPHENYL)METHYL)-1H-PYRROLE-2,5-DIONE
methyl 1-(6-chloropyridazin-3-yl)piperidine-4-carboxylate
1-(3,4,5-Trimethoxy-2-nitrophenyl)ethanone
C11H13NO6 (255.07428380000002)
6-Boc-4-chloro-6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidine
7-OXO-2-PHENYL-4,7-DIHYDROPYRAZOLO[1,5-A]PYRIMIDINE-6-CARBOXYLIC ACID
C13H9N3O3 (255.06438839999998)
1-[4-(trifluoromethoxy)phenyl]pyrrole-2-carbaldehyde
2-[4-[(5-NITRO-2-PYRIDYL)OXY]PHENYL]ACETONITRILE
C13H9N3O3 (255.06438839999998)
6-BROMO-2,4,4-TRIMETHYL-2,4-DIHYDRO-1H-BENZO[D][1,3]OXAZINE
ETHYL 3-AMINO-4-CHLOROBENZO[B!THIOPHEN-2-CARBOXYLATE
3,4-Dichloro-5-fluoro-[1,1-biphenyl]-2-amine
C12H8Cl2FN (255.00177999999997)
3-chloro-N-[4-(1,3-dioxolan-2-yl)phenyl]propanamide
CARBOXYMETHYL-(2,4-DIHYDROXYBENZYL)AMINO]ACETICACID
C11H13NO6 (255.07428380000002)
4-Thiazoleacetic acid, 2-phenyl-, hydrochloride (1:1)
2-ISOPROPOXY-5-(TRIFLUOROMETHYL)ANILINE HYDROCHLORIDE
C10H13ClF3NO (255.06377139999998)
3-(1,1,3-TRIOXO-1,3-DIHYDRO-1LAMBDA6-BENZO[D]ISOTHIAZOL-2-YL)-PROPIONIC ACID
C10H9NO5S (255.02014239999997)
p-(p-Nitroanilino)phenyl isocyanate
C13H9N3O3 (255.06438839999998)
1-naphthalen-1-yl-5-oxo-pyrrolidine-3-carboxylic acid
2-[[2-(AMINOCARBONYL)-5-ETHOXYPHENYL]THIO]ACETIC ACID
2-chloromethyl-3,4-dimethoxy pyridine hydrochloride
C9H9N3O2S2 (255.01361740000002)
N-(1,6-Dihydro-6-oxopurin-2-yl)-benzamide
C12H9N5O2 (255.07562140000002)
2-methyl-2-[(nitrooxy)methyl]propane-1,3-diyl dinitrate
1-[(2-FLUOROPHENYL)METHYL]-1H-INDOLE-2,3-DIONE
C15H10FNO2 (255.06955320000003)
METHYL 1-(6-CHLORO-3-PYRIDAZINYL)PIPERIDINE-3-CARBOXYLATE
3-Bromo-1-oxa-8-azaspiro[4.5]decane hydrochloride (1:1)
METHYL 2-CYANO-3-FLUORO-[1,1-BIPHENYL]-4-CARBOXYLATE
C15H10FNO2 (255.06955320000003)
3-(2-methyl-1,3-benzoxazol-3-ium-3-yl)-1-propanesulfonate
3-[(4-chlorophenoxy)methyl]-4-methyl-1H-1,2,4-triazole-5-thione
thiazosulfone
C9H9N3O2S2 (255.01361740000002)
C254 - Anti-Infective Agent > C849 - Sulfone Anti-Infective Agent
2,4-Pentanedione - manganese (2:1)
C10H16MnO4 (255.04289959999997)
1-Methyl-7-phenyl-1H-pyrimido[4,5-d][1,3]oxazine-2,4-dione
C13H9N3O3 (255.06438839999998)
7-chloro-6-methylquinoline-2-carboximidamide,hydrochloride
3-ethyl-2-(2-hydroxy-1-propenyl)benzothiazolium chloride
1-PHENYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE-4-CARBOXAMIDE
4-[3-(trifluoromethyl)phenyl]piperazine-1-carbonitrile
C12H12F3N3 (255.09832679999997)
4-(4-Fluorobenzoyl)-3-(hydroxymethyl)benzonitrile
C15H10FNO2 (255.06955320000003)
METHYL 2-[TERT-BUTOXYCARBONYLIMINO]-3,3,3-TRIFLUOROPROPIONATE
C9H12F3NO4 (255.07183879999997)
1-3-[3-(TRIFLUOROMETHYL)PHENYL]ISOXAZOL-5-YL-ETHAN-1-ONE
10H-Pyridazino[6,1-b]quinazoline-2-carboxylic acid, 7-methyl-10-oxo-
C13H9N3O3 (255.06438839999998)
2-AMINO-3-(5-CHLOROBENZOóB!THIOPHEN-3-YL)PROPANOIC ACID, TECH
1,1-DIOXO-4-PHENETHYLAMINO-TETRAHYDRO-1LAMBDA6-THIOPHEN-3-OL
(2Z)-2-[Cyano(2,3-dichlorophenyl)methylene]hydrazinecarboximidamide
3-(1,3-dioxopropan-2-yl)-4-nitrobenzoic acid,hydrate
5-[(1,3-DIOXO-1,3-DIYHDRO-2H-ISOINDOL-2-YL)METHYL]-2-FURALDEHYDE
(1R,2S,3R)-1-(2-(ISOXAZOL-3-YL)-1H-IMIDAZOL-5-YL)BUTANE-1,2,3,4-TETRAOL
2-(4-(trifluoromethyl)phenoxy)propan-1-amine
C10H13ClF3NO (255.06377139999998)
2-(6-bromo-1,2,3,4-tetrahydroisoquinolin-4-yl)ethanol
2-(7-bromo-1,2,3,4-tetrahydroisoquinolin-4-yl)ethanol
2-(8-bromo-1,2,3,4-tetrahydroisoquinolin-4-yl)ethanol
ethyl 1-(chlorosulfonyl)piperidine-3-carboxylate(SALTDATA: FREE)
2,3,4-Pyridinetricarboxylic acid,5-methoxy-6-methyl-
2-(2,3-Dichlorophenyl)-2-guanidinyliminoacetonitrile
Methyl 7-chloro-8-fluoro-4-hydroxyquinoline-2-carboxylate
Diroximel fumarate
C11H13NO6 (255.07428380000002)
L - Antineoplastic and immunomodulating agents > L04 - Immunosuppressants > L04A - Immunosuppressants C78272 - Agent Affecting Nervous System
(3-(N-cyclopropylsulfamoyl)-4-methylphenyl)boronic acid
1-(2-Chloro-6-methyl-pyrimidin-4-yl)-piperidine-3-carboxylic acid
2,3-Dicyano-1,4-dihydroxy-5-nitronaphthalene
C12H5N3O4 (255.02800499999998)
5-([(TERT-BUTOXY)CARBONYL]AMINO)-2-FLUOROBENZOIC ACID
C12H14FNO4 (255.09068159999998)
Diethyl,2-(3-fluoropyridin-2-yl)malonate
C12H14FNO4 (255.09068159999998)
1-(2,4-Dichlorobenzyl)-5-methyl-1H-pyrazol-3-amine
2-Azaspiro[3.3]heptane-6-carboxylic acid trifluoroacetate
C9H12F3NO4 (255.07183879999997)
4-BROMO-2,6-BIS(1-METHYLETHYL)BENZENAMINE
C12H18BrN (255.06225279999998)
(R)-2-(2,4-difluoro-phenyl)-3-[1H-1,2,4]triazoll-1-yl-propane-1,2-diol
methyl 2-(1,1,3-trioxo-1,2-benzothiazol-2-yl)acetate
C10H9NO5S (255.02014239999997)
(4-(TERT-BUTYLCARBAMOYL)-3-CHLOROPHENYL)BORONIC ACID
2-(2,4-DIFLUOROPHENYL)THIAZOLE-4-CARBOXAMIDOXIME
C10H7F2N3OS (255.02778759999998)
4-(2-MORPHOLIN-4-YL-ETHOXY)-BENZOIC ACID
C9H10BrN3O (255.00071899999998)
(4-(N-Cyclopropylsulfamoyl)-2-methylphenyl)boronic acid
Methyl (S)-3-acetamido-3-(4-chlorophenyl)propanoate
tert-Butyl 2-chloro-5H-pyrrolo[3,4-d]pyrimidine-6(7H)-carboxylate
4-(4-Chlorophenoxy)-3,5-difluoroaniline
C12H8ClF2NO (255.02624519999998)
2,4-DIMETHYL-5-PHENYLIMIDAZO[1,5-B]PYRIDAZINE-7-THIOL
sodium,2-chloro-4-[(4-oxocyclohexa-2,5-dien-1-ylidene)amino]phenolate
3-(2,4-dimethoxyphenyl)-1h-pyrazol-5-amine hydrochloride
6-AMINO-6-DEOXY-1,2-O-ISOPROPYLIDENE-α-D-GLUCOFURANOSE HYDROCHLORIDE
C9H18ClNO5 (255.08734479999998)
(3-(tert-Butylcarbamoyl)-4-chlorophenyl)boronic acid
[2-[2-methyl-5-(trifluoromethyl)pyrazol-3-yl]phenyl]methanamine
C12H12F3N3 (255.09832679999997)
(2-AMINO-5-TRIFLUOROMETHYL-3H-IMIDAZOL-4-YL)-PHENYL-METHANONE
3-(2-Chloro-6-fluorophenyl)-5-methylisoxazole-4-carboxylic acid
Methyl 1-(trifluoromethyl)isoquinoline-3-carboxylate
1-(4-[2-NITRO-4-(TRIFLUOROMETHYL)PHENYL]PIPERAZINO)-2-PYRIDINIUM-1-YLETHAN-1-ONECHLORIDE
Sparfosic acid
C274 - Antineoplastic Agent > C186664 - Cytotoxic Chemotherapeutic Agent > C272 - Antimetabolite D018377 - Neurotransmitter Agents > D018846 - Excitatory Amino Acids D000890 - Anti-Infective Agents > D000998 - Antiviral Agents D009676 - Noxae > D000963 - Antimetabolites D000970 - Antineoplastic Agents D004791 - Enzyme Inhibitors C471 - Enzyme Inhibitor
N-(Phosphonoacetyl)aspartic acid
D018377 - Neurotransmitter Agents > D018846 - Excitatory Amino Acids D000890 - Anti-Infective Agents > D000998 - Antiviral Agents D009676 - Noxae > D000963 - Antimetabolites D000970 - Antineoplastic Agents D004791 - Enzyme Inhibitors
2-Amino-4-thiophen-2-yl-5,6,7,8-tetrahydroquinoline-3-carbonitrile
2-[3-(2-Methylphenyl)-4-oxo-1,3-thiazolidin-2-ylidene]propanedinitrile
C13H9N3OS (255.04663039999997)
N-[(3-bromophenyl)methyl]-1-pentanamine
C12H18BrN (255.06225279999998)
N-(4-Hydroxy-3,5-dimethoxybenzoyl)glycine
C11H13NO6 (255.07428380000002)
Sulbactam sodium
C8H10NNaO5S (255.01773699999998)
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D065093 - beta-Lactamase Inhibitors D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D047090 - beta-Lactams D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D010406 - Penicillins D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D007769 - Lactams C2140 - Adjuvant > C183118 - Beta-lactamase Inhibitor D004791 - Enzyme Inhibitors
Alrestatin
D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents > D010276 - Parasympatholytics C471 - Enzyme Inhibitor > C72880 - Aldose Reductase Inhibitor D004791 - Enzyme Inhibitors
beta-D-ribosylnicotinate
C11H13NO6 (255.07428380000002)
beta-d-ribosylnicotinate is slightly soluble (in water) and a moderately acidic compound (based on its pKa). beta-d-ribosylnicotinate can be found in a number of food items such as turnip, chanterelle, garland chrysanthemum, and canola, which makes beta-d-ribosylnicotinate a potential biomarker for the consumption of these food products. β-d-ribosylnicotinate is slightly soluble (in water) and a moderately acidic compound (based on its pKa). β-d-ribosylnicotinate can be found in a number of food items such as turnip, chanterelle, garland chrysanthemum, and canola, which makes β-d-ribosylnicotinate a potential biomarker for the consumption of these food products.
(2S)-7-hydroxy-4-oxo-2-phenyl-2,3-dihydrochromen-5-olate
3,8-dihydroxy-6-methyl-9-oxo-10H-anthracen-1-olate
2-Amino-7-[(2R)-2,3-dihydroxypropanoyl]-5,6,7,8-tetrahydro-3H-pteridin-4-one
4-[3,4-Dihydroxy-2-(hydroxymethyl)thiolan-1-ium-1-yl]butane-1,2,3-triol
Isoliquiritigenin(1-)
A phenolate anion obtained by deprotonation of the hydroxy group located at the position ortho to the carbonyl group of isoliquiritigenin. It is the major microspecies at pH 7.3 (according to Marvin v 6.2.0.).
1-Butyl-3-[(E)-(3-methylthiophen-2-yl)methylideneamino]thiourea
2-methoxy-N-(5-thiophen-2-yl-1,3,4-thiadiazol-2-yl)acetamide
C9H9N3O2S2 (255.01361740000002)
2,4-Difluorobenzoic acid [2-(cyclopropylamino)-2-oxoethyl] ester
2-(2-Furanyl)-5-(2-furanylmethylamino)-4-oxazolecarbonitrile
C13H9N3O3 (255.06438839999998)
ganciclovir
An oxopurine that is guanine substituted by a [(1,3-dihydroxypropan-2-yl)oxy]methyl group at position 9. Ganciclovir is an antiviral drug used to treat or prevent AIDS-related cytomegalovirus infections. J - Antiinfectives for systemic use > J05 - Antivirals for systemic use > J05A - Direct acting antivirals > J05AB - Nucleosides and nucleotides excl. reverse transcriptase inhibitors S - Sensory organs > S01 - Ophthalmologicals > S01A - Antiinfectives > S01AD - Antivirals D000890 - Anti-Infective Agents > D000998 - Antiviral Agents C471 - Enzyme Inhibitor > C29575 - DNA Polymerase Inhibitor C254 - Anti-Infective Agent > C281 - Antiviral Agent Ganciclovir (BW 759), a nucleoside analogue, is an orally active antiviral agent with activity against CMV. Ganciclovir also has activity in vitro against members of the herpes group and some other DNA viruses. Ganciclovir inhibits the in vitro replication of human herpes viruses (HSV 1 and 2, CMV) and adenovirus serotypes 1, 2, 4, 6, 8, 10, 19, 22 and 28. Ganciclovir has an IC50 of 5.2 μM for feline herpesvirus type-1 (FHV-1) and can diffuse into the brain[1][2][3].
Nicotinamide riboside
COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials, COVID-19 Disease Map C26170 - Protective Agent > C275 - Antioxidant Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS
7,8-Dihydroneopterin
A neopterin where positions C-7 and C-8 have been hydrogenated. 7,8-Dihydroneopterin, an inflammation marker, induces cellular apoptosis in astrocytes and neurons via enhancement of nitric oxide synthase (iNOS) expression. 7,8-Dihydroneopterin can be used in the research of neurodegenerative diseases[1].
N-Ribosylnicotinamide
A pyridine nucleoside consisting of nicotinamide with a beta-D-ribofuranosyl moiety at the 1-position.
norbaeocystin(1-)
C10H12N2O4P (255.05346619999997)
An organophosphate oxoanion obtained by deprotonation of the phosphate and protonation of the amino group of norbaeocystin; major species at pH 7.3.
2'-Deoxy-5-formylcytidine
2'-Deoxy-5-formylcytidine is an effective internal triplet photosensitizer in DNA. 2'-Deoxy-5-formylcytidine could act as a new hot spot in DNA photodamage[1].
2'-O,4'-C-Methylenecytidine
2'-O,4'-C-Methylenecytidine (LNA-C(Bz)) is a bicyclic nucleoside analogue with fixed N-type conformation. 2'-O,4'-C-Methylenecytidine can be used to synthesize oligonucleotides. 2'-O,4'-C-Methylenecytidine forms duplexes with complementary DNA and RNA strands[1][2].
1-thiophen-2-yl-n-[2-(trifluoromethyl)phenyl]methanimine
2-(2-hydroxyphenyl)-1,3-benzoxazole-4-carboxylic acid
7-hydroxy-2-methoxy-6-methyl-9h-carbazole-1-carbaldehyde
6-amino-5-chloro-3-[(1s)-1,2-dihydroxyethyl]-4-imino-1h-indol-7-one
4-benzyl-3-oxo-1h,4h-pyrrolo[2,1-c][1,4]oxazine-6-carbaldehyde
1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-3-(c-hydroxycarbonimidoyl)-1λ⁵-pyridin-1-ylium
(1s,2r)-1-(4-hydroxy-2-imino-7,8-dihydro-1h-pteridin-6-yl)propane-1,2,3-triol
ethyl 6-[(ethoxysulfanyl)carbonyl]pyridine-2-carboxylate
2-amino-3-({[(2-carboxy-2-hydroxyethyl)sulfanyl]methyl}sulfanyl)propanoic acid
1,4-dimethyl (2s)-2-(1h-pyrrole-2-carbonyloxy)butanedioate
C11H13NO6 (255.07428380000002)